Drosophila melanogaster

67 known processes

HLHmbeta (Dmel_CG14548)

E(spl) region transcript mbeta

(Aliases: E(spl) mbeta,Mbeta,E(Spl) HLH-Mbeta,Dmel\CG14548,bHLHb34,Dm-mA,E(spl),E(spl)-Mbeta,HLH-mbeta,mbeta,CG14548,m-beta,E(Spl)mbeta,E(spl)beta,HLHmA,E(spl)mbeta,mA,E(spl)mA,E(spl)-mbeta,E(spl)Mbeta)

HLHmbeta biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ precursor cell fate determination GO:0016360 19 0.999
Fly
neuron fate determination GO:0048664 1 0.997
Mouse
sensory organ boundary specification GO:0008052 22 0.978
Fly
positive regulation of bmp signaling pathway GO:0030513 5 0.976
Mouse
regulation of timing of cell differentiation GO:0048505 1 0.975
Mouse
formation of anatomical boundary GO:0048859 37 0.956
Fly
regulation of mitosis GO:0007088 56 0.952
Fly
formation of organ boundary GO:0010160 30 0.934
Fly
organ formation GO:0048645 39 0.908
Fly
nephron epithelium morphogenesis GO:0072088 3 0.863
Mouse
cell fate commitment involved in pattern specification GO:0060581 31 0.861
Fly
organelle fission GO:0048285 340 0.860
Fly
stem cell maintenance GO:0019827 67 0.855
Human Mouse Rat
glial cell fate commitment GO:0021781 3 0.848
Mouse
regionalization GO:0003002 416 0.838
Zebrafish Mouse Worm Fly
cell fate determination involved in pattern specification GO:0060582 19 0.834
Fly
axon ensheathment in central nervous system GO:0032291 3 0.832
Mouse
open tracheal system development GO:0007424 204 0.829
Fly
nuclear division GO:0000280 332 0.825
Fly
r7 cell differentiation GO:0045466 43 0.801
Fly
neuroblast proliferation GO:0007405 74 0.797
Fly
telencephalon development GO:0021537 2 0.796
Mouse
epidermal cell differentiation GO:0009913 51 0.792
Mouse Worm
neural precursor cell proliferation GO:0061351 75 0.777
Fly
sex determination GO:0007530 18 0.775
Fly
primary sex determination soma GO:0007539 2 0.772
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.772
cell division GO:0051301 248 0.771
Fly
kidney morphogenesis GO:0060993 3 0.770
Mouse
salivary gland development GO:0007431 162 0.769
Fly
cell fate specification GO:0001708 71 0.767
Worm
connective tissue development GO:0061448 3 0.750
Human Mouse
forebrain development GO:0030900 2 0.748
Mouse Rat
regulation of glial cell differentiation GO:0045685 1 0.746
Mouse
rhythmic process GO:0048511 106 0.745
Mouse
regulation of neuron differentiation GO:0045664 103 0.732
Mouse Rat
regulation of notch signaling pathway GO:0008593 100 0.731
Mouse
r1 r6 cell differentiation GO:0048052 4 0.731
Fly
regulation of neurogenesis GO:0050767 158 0.728
Zebrafish Mouse Rat Fly
nephron morphogenesis GO:0072028 3 0.725
Mouse
axon development GO:0061564 297 0.723
Zebrafish
cell fate determination GO:0001709 91 0.720
Mouse Fly
eye photoreceptor cell differentiation GO:0001754 145 0.720
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.712
photoreceptor cell differentiation GO:0046530 170 0.710
Fly
negative regulation of transcription dna templated GO:0045892 237 0.705
dorsal ventral pattern formation GO:0009953 133 0.704
Fly
regulation of neuroblast proliferation GO:1902692 34 0.703
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.702
morphogenesis of embryonic epithelium GO:0016331 94 0.690
Mouse
tissue morphogenesis GO:0048729 297 0.683
Mouse
dendrite development GO:0016358 204 0.679
Fly
hindbrain development GO:0030902 2 0.677
Mouse
mesoderm development GO:0007498 78 0.668
Fly
gliogenesis GO:0042063 80 0.665
Zebrafish Mouse Rat
embryonic epithelial tube formation GO:0001838 6 0.665
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.661
peripheral nervous system development GO:0007422 52 0.659
Zebrafish
compound eye development GO:0048749 307 0.655
Fly
tube formation GO:0035148 21 0.654
Mouse
nerve development GO:0021675 6 0.642
Mouse
tyrosine phosphorylation of stat protein GO:0007260 1 0.638
Mouse
imaginal disc pattern formation GO:0007447 91 0.636
Fly
single organism behavior GO:0044708 391 0.626
Fly
nephron development GO:0072006 3 0.623
Mouse
axonogenesis GO:0007409 290 0.606
Zebrafish
central nervous system development GO:0007417 201 0.603
Zebrafish Mouse Rat Fly
positive regulation of transcription dna templated GO:0045893 266 0.601
Mouse
dendrite morphogenesis GO:0048813 199 0.599
Fly
respiratory system development GO:0060541 213 0.599
Fly
stem cell differentiation GO:0048863 117 0.594
Human Mouse Rat
embryonic morphogenesis GO:0048598 206 0.588
Zebrafish Mouse
tube development GO:0035295 244 0.587
Zebrafish Mouse Fly
regulation of organelle organization GO:0033043 196 0.586
Fly
regulation of gliogenesis GO:0014013 11 0.578
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.576
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.568
Zebrafish Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.564
tube morphogenesis GO:0035239 191 0.563
Mouse Fly
regulation of cell development GO:0060284 215 0.561
Zebrafish Mouse Rat Fly
regulation of cell cycle process GO:0010564 181 0.560
Fly
glial cell development GO:0021782 27 0.558
Mouse
regulation of cell cycle GO:0051726 291 0.558
Zebrafish Fly
regulation of mitotic cell cycle GO:0007346 190 0.556
Fly
eye development GO:0001654 323 0.554
Zebrafish Mouse Fly
neuronal stem cell maintenance GO:0097150 4 0.553
Human Mouse Rat
kidney epithelium development GO:0072073 3 0.547
Mouse
sensory organ morphogenesis GO:0090596 260 0.543
Fly
renal tubule morphogenesis GO:0061333 44 0.540
Mouse
nephron tubule development GO:0072080 3 0.539
Mouse
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.539
Mouse
positive regulation of signal transduction GO:0009967 223 0.538
Mouse
gland development GO:0048732 191 0.534
Fly
renal system development GO:0072001 72 0.527
Mouse
negative regulation of neurogenesis GO:0050768 53 0.527
Zebrafish Mouse Rat
urogenital system development GO:0001655 72 0.526
Mouse
somatic sex determination GO:0018993 2 0.525
Fly
regulation of nuclear division GO:0051783 58 0.508
Fly
nephron epithelium development GO:0072009 3 0.507
Mouse
nephron tubule morphogenesis GO:0072078 3 0.500
Mouse
malpighian tubule morphogenesis GO:0007443 44 0.499
hair cell differentiation GO:0035315 47 0.492
Mouse
epidermis development GO:0008544 65 0.491
Mouse Worm
sex determination establishment of x a ratio GO:0007540 1 0.489
Fly
positive regulation of nervous system development GO:0051962 69 0.488
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.488
positive regulation of multicellular organismal process GO:0051240 143 0.487
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.479
Mouse
eye morphogenesis GO:0048592 260 0.478
Fly
compound eye morphogenesis GO:0001745 249 0.477
Fly
negative regulation of biosynthetic process GO:0009890 277 0.477
transcription from rna polymerase ii promoter GO:0006366 368 0.469
negative regulation of rna biosynthetic process GO:1902679 240 0.460
negative regulation of rna metabolic process GO:0051253 251 0.457
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.456
Mouse
camera type eye development GO:0043010 4 0.456
Mouse
immune system process GO:0002376 347 0.455
Rat
positive regulation of rna biosynthetic process GO:1902680 266 0.453
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.453
Mouse
mitotic nuclear division GO:0007067 213 0.448
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.441
neuron projection guidance GO:0097485 241 0.441
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.441
Zebrafish
stem cell fate specification GO:0048866 2 0.439
neurological system process GO:0050877 358 0.434
Mouse Fly
dosage compensation GO:0007549 16 0.433
Fly
cell maturation GO:0048469 144 0.426
Mouse
positive regulation of response to stimulus GO:0048584 323 0.426
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.419
Mouse
morphogenesis of an epithelium GO:0002009 276 0.416
Mouse
regulation of bmp signaling pathway GO:0030510 23 0.413
Mouse
epithelial cell differentiation GO:0030855 322 0.412
Mouse Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.409
negative regulation of stem cell differentiation GO:2000737 8 0.407
Human
positive regulation of gene expression GO:0010628 290 0.405
Mouse
kidney development GO:0001822 3 0.403
Mouse
positive regulation of mitotic cell cycle GO:0045931 34 0.403
Fly
regulation of multicellular organismal development GO:2000026 414 0.402
Zebrafish Mouse Rat Fly
positive regulation of cellular component organization GO:0051130 156 0.397
Fly
neuroblast fate specification GO:0014018 2 0.397
renal tubule development GO:0061326 64 0.395
Mouse
neuron fate commitment GO:0048663 50 0.389
Mouse
head development GO:0060322 135 0.386
Zebrafish Mouse Rat Fly
segment specification GO:0007379 33 0.383
Zebrafish Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.380
epithelial tube morphogenesis GO:0060562 88 0.379
Mouse
skin development GO:0043588 65 0.371
Mouse Worm
regulation of nervous system development GO:0051960 248 0.371
Zebrafish Mouse Rat Fly
proximal distal pattern formation GO:0009954 15 0.369
Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.368
Fly
negative regulation of cell development GO:0010721 62 0.368
Zebrafish Mouse Rat
bmp signaling pathway GO:0030509 27 0.367
Mouse
regulation of stem cell proliferation GO:0072091 40 0.358
Fly
stem cell proliferation GO:0072089 88 0.357
Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.357
response to abiotic stimulus GO:0009628 341 0.351
Fly
negative regulation of nervous system development GO:0051961 92 0.349
Zebrafish Mouse Rat
embryonic hindgut morphogenesis GO:0048619 48 0.341
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.338
Rat
negative regulation of gene expression GO:0010629 387 0.336
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.332
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.329
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.328
cellular amine metabolic process GO:0044106 12 0.326
nephron tubule formation GO:0072079 3 0.324
Mouse
regulation of cell division GO:0051302 72 0.321
Fly
positive regulation of cell cycle GO:0045787 43 0.319
Zebrafish Fly
positive regulation of cell cycle process GO:0090068 28 0.318
Fly
central nervous system neuron differentiation GO:0021953 8 0.310
Rat
positive regulation of developmental process GO:0051094 143 0.310
Fly
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.308
peripheral nervous system neuron differentiation GO:0048934 8 0.303
Zebrafish
anterior posterior pattern specification GO:0009952 136 0.302
Zebrafish Mouse Worm
protein complex assembly GO:0006461 200 0.298
Mouse
humoral immune response GO:0006959 117 0.294
negative regulation of gliogenesis GO:0014014 6 0.285
Mouse
salivary gland morphogenesis GO:0007435 145 0.279
Fly
regulation of gene expression epigenetic GO:0040029 128 0.272
Fly
negative regulation of multicellular organismal process GO:0051241 142 0.271
Zebrafish Mouse Rat
segmentation GO:0035282 207 0.270
Zebrafish Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.269
Mouse
negative regulation of immune system process GO:0002683 50 0.268
Rat
startle response GO:0001964 16 0.262
Fly
regulation of cell morphogenesis GO:0022604 163 0.262
digestive tract morphogenesis GO:0048546 127 0.258
appendage development GO:0048736 401 0.258
negative regulation of cell differentiation GO:0045596 143 0.257
Human Zebrafish Mouse Rat
gland morphogenesis GO:0022612 145 0.250
Fly
cellular response to dna damage stimulus GO:0006974 223 0.247
Fly
embryonic organ development GO:0048568 50 0.244
Zebrafish
smoothened signaling pathway GO:0007224 49 0.239
Mouse
appendage morphogenesis GO:0035107 397 0.238
negative regulation of notch signaling pathway GO:0045746 41 0.237
enzyme linked receptor protein signaling pathway GO:0007167 179 0.232
Mouse
hindgut morphogenesis GO:0007442 58 0.228
regulation of immune system process GO:0002682 176 0.221
Rat
stem cell development GO:0048864 79 0.219
Human Mouse Rat
positive regulation of cell differentiation GO:0045597 64 0.219
Fly
axon guidance GO:0007411 233 0.219
regulation of membrane potential GO:0042391 35 0.218
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.213
Mouse
hematopoietic progenitor cell differentiation GO:0002244 1 0.213
Rat
cellular ketone metabolic process GO:0042180 24 0.211
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.207
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.206
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.204
Fly
larval locomotory behavior GO:0008345 27 0.202
Fly
positive regulation of neural precursor cell proliferation GO:2000179 8 0.202
Fly
spinal cord development GO:0021510 1 0.197
negative regulation of developmental process GO:0051093 201 0.195
Human Zebrafish Mouse Rat
antimicrobial humoral response GO:0019730 99 0.194
regulation of cellular amino acid metabolic process GO:0006521 0 0.194
notch signaling pathway GO:0007219 120 0.193
Human Zebrafish Mouse Fly
regulation of cell differentiation GO:0045595 302 0.191
Human Zebrafish Mouse Rat Fly
cranial nerve development GO:0021545 1 0.191
Mouse
positive regulation of protein metabolic process GO:0051247 128 0.188
Zebrafish Mouse
regulation of response to stress GO:0080134 200 0.188
Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.186
positive regulation of notch signaling pathway GO:0045747 34 0.180
Mouse
imaginal disc derived appendage development GO:0048737 399 0.180
positive regulation of cellular protein metabolic process GO:0032270 118 0.177
Zebrafish Mouse
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.173
embryonic organ morphogenesis GO:0048562 5 0.173
Zebrafish
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.173
Mouse
brain development GO:0007420 120 0.170
Zebrafish Mouse Rat Fly
peripheral nervous system neuron development GO:0048935 8 0.170
Zebrafish
adult behavior GO:0030534 137 0.169
Fly
locomotory behavior GO:0007626 176 0.169
Fly
wing disc pattern formation GO:0035222 66 0.168
Fly
glial cell differentiation GO:0010001 35 0.168
Mouse Rat
organic acid metabolic process GO:0006082 103 0.166
cell proliferation GO:0008283 299 0.165
Human Fly
axon ensheathment GO:0008366 10 0.164
Mouse
positive regulation of cell development GO:0010720 61 0.163
Fly
protein modification process GO:0036211 438 0.158
Zebrafish Mouse
positive regulation of rna metabolic process GO:0051254 271 0.157
Mouse
regulation of response to dna damage stimulus GO:2001020 23 0.152
Fly
positive regulation of molecular function GO:0044093 136 0.152
Zebrafish
developmental cell growth GO:0048588 52 0.151
regulation of neural precursor cell proliferation GO:2000177 35 0.150
Fly
neuroblast differentiation GO:0014016 29 0.146
regulation of cell proliferation GO:0042127 163 0.144
Human Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.143
neuromuscular process GO:0050905 21 0.142
Fly
positive regulation of signaling GO:0023056 243 0.138
Mouse
taxis GO:0042330 304 0.135
protein phosphorylation GO:0006468 169 0.134
Zebrafish Mouse
oxoacid metabolic process GO:0043436 103 0.133
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.128
localization of cell GO:0051674 257 0.127
positive regulation of cellular biosynthetic process GO:0031328 316 0.126
Mouse
regulation of protein modification process GO:0031399 112 0.126
Zebrafish Mouse
cell adhesion GO:0007155 136 0.125
Mouse
cellular protein modification process GO:0006464 438 0.123
Zebrafish Mouse
wing disc dorsal ventral pattern formation GO:0048190 47 0.122
Fly
ensheathment of neurons GO:0007272 10 0.122
Mouse
spinal cord patterning GO:0021511 1 0.121
eye photoreceptor cell fate commitment GO:0042706 37 0.120
adult locomotory behavior GO:0008344 76 0.120
Fly
stem cell fate commitment GO:0048865 25 0.119
peptidyl tyrosine phosphorylation GO:0018108 24 0.116
Mouse
wing disc morphogenesis GO:0007472 344 0.115
phosphorylation GO:0016310 294 0.114
Zebrafish Mouse
immune response GO:0006955 246 0.111
intracellular signal transduction GO:0035556 300 0.110
Mouse
regulation of cellular response to stress GO:0080135 89 0.110
Fly
exocrine system development GO:0035272 162 0.109
Fly
regulation of neuron projection development GO:0010975 69 0.109
peptidyl amino acid modification GO:0018193 105 0.108
Mouse
bolwig s organ development GO:0055034 8 0.108
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.106
Zebrafish
positive regulation of cell communication GO:0010647 250 0.106
Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.106
hindgut development GO:0061525 58 0.105
regulation of molecular function GO:0065009 217 0.103
Zebrafish
endoderm development GO:0007492 6 0.102
Zebrafish
multi organism behavior GO:0051705 175 0.101
compound eye photoreceptor fate commitment GO:0001752 36 0.101
positive regulation of intracellular signal transduction GO:1902533 116 0.101
Mouse
peptidyl tyrosine modification GO:0018212 24 0.100
Mouse
developmental maturation GO:0021700 172 0.097
Mouse
positive regulation of protein modification process GO:0031401 58 0.094
Zebrafish Mouse
regulation of intracellular signal transduction GO:1902531 236 0.094
Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.093
neuron projection extension GO:1990138 32 0.093
glandular epithelial cell differentiation GO:0002067 1 0.092
positive regulation of stem cell proliferation GO:2000648 8 0.092
Fly
body morphogenesis GO:0010171 2 0.092
response to biotic stimulus GO:0009607 294 0.091
regulation of epithelial cell differentiation GO:0030856 4 0.091
immune system development GO:0002520 57 0.089
Rat
biological adhesion GO:0022610 138 0.089
Mouse
jak stat cascade GO:0007259 49 0.088
Mouse
regulation of protein serine threonine kinase activity GO:0071900 25 0.088
Zebrafish
muscle organ development GO:0007517 127 0.085
regulation of protein metabolic process GO:0051246 256 0.084
Zebrafish Mouse
organonitrogen compound metabolic process GO:1901564 318 0.083
transmission of nerve impulse GO:0019226 12 0.082
Mouse
cell growth GO:0016049 108 0.082
spinal cord dorsal ventral patterning GO:0021513 1 0.081
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.080
Mouse
hemopoiesis GO:0030097 46 0.080
Rat
positive regulation of protein kinase activity GO:0045860 25 0.079
Zebrafish
apoptotic process involved in morphogenesis GO:0060561 3 0.079
neuroblast fate commitment GO:0014017 19 0.078
ommatidial rotation GO:0016318 20 0.077
gastrulation with mouth forming first GO:0001703 36 0.077
multicellular organismal signaling GO:0035637 12 0.076
Mouse
chaeta development GO:0022416 97 0.075
malpighian tubule tip cell differentiation GO:0061382 9 0.075
positive regulation of cell proliferation GO:0008284 47 0.074
Human Fly
regulation of phosphate metabolic process GO:0019220 210 0.074
Zebrafish Mouse
larval behavior GO:0030537 42 0.073
Fly
stem cell fate determination GO:0048867 15 0.073
negative regulation of cell cycle process GO:0010948 109 0.071
actin filament based process GO:0030029 220 0.070
neuron fate specification GO:0048665 12 0.069
gastrulation involving germ band extension GO:0010004 36 0.069
imaginal disc derived wing vein specification GO:0007474 48 0.069
positive regulation of catalytic activity GO:0043085 118 0.068
Zebrafish
cellular amino acid metabolic process GO:0006520 61 0.067
epithelial tube formation GO:0072175 7 0.067
Mouse
neuron recognition GO:0008038 101 0.066
regulation of catalytic activity GO:0050790 185 0.064
Zebrafish
gastrulation GO:0007369 70 0.064
central nervous system neuron development GO:0021954 8 0.063
regulation of anatomical structure size GO:0090066 163 0.062
positive regulation of cell division GO:0051781 16 0.061
Fly
regulation of kinase activity GO:0043549 53 0.061
Zebrafish
neuronal action potential GO:0019228 10 0.060
Mouse
regulation of cellular amide metabolic process GO:0034248 39 0.059
chaeta morphogenesis GO:0008407 42 0.059
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.059
negative regulation of glial cell proliferation GO:0060253 6 0.058
amine metabolic process GO:0009308 12 0.058
developmental growth GO:0048589 280 0.057
digestive tract development GO:0048565 149 0.057
regulation of antimicrobial peptide production GO:0002784 44 0.057
positive regulation of neurogenesis GO:0050769 41 0.057
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.057
neuroblast fate determination GO:0007400 12 0.057
regulation of protein kinase activity GO:0045859 51 0.056
Zebrafish
axon extension involved in axon guidance GO:0048846 10 0.056
medulla oblongata development GO:0021550 2 0.056
locomotor rhythm GO:0045475 56 0.056
muscle structure development GO:0061061 224 0.056
carboxylic acid metabolic process GO:0019752 92 0.056
regulation of immune response GO:0050776 118 0.055
small molecule metabolic process GO:0044281 305 0.055
apoptotic process GO:0006915 159 0.054
multi organism reproductive behavior GO:0044705 121 0.052
glial cell proliferation GO:0014009 13 0.052
positive regulation of phosphorus metabolic process GO:0010562 139 0.051
Zebrafish Mouse
protein complex biogenesis GO:0070271 201 0.051
Mouse
regulation of cell projection organization GO:0031344 92 0.051
regulation of cellular protein metabolic process GO:0032268 243 0.050
Zebrafish Mouse
response to other organism GO:0051707 293 0.049
macromolecular complex assembly GO:0065003 256 0.048
Mouse
action potential GO:0001508 13 0.048
Mouse
epithelial cell development GO:0002064 274 0.046
response to hypoxia GO:0001666 53 0.046
Fly
regulation of humoral immune response GO:0002920 51 0.046
positive regulation of kinase activity GO:0033674 25 0.045
Zebrafish
regulation of stem cell differentiation GO:2000736 14 0.045
Human
multi multicellular organism process GO:0044706 123 0.044
response to external biotic stimulus GO:0043207 293 0.044
regulation of immune effector process GO:0002697 52 0.044
regulation of protein phosphorylation GO:0001932 64 0.043
Zebrafish Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.043
Zebrafish Mouse
photoreceptor cell fate commitment GO:0046552 41 0.042
regeneration GO:0031099 16 0.042
response to oxygen levels GO:0070482 59 0.042
Fly
negative regulation of mitotic cell cycle GO:0045930 109 0.041
sensory perception of sound GO:0007605 56 0.041
response to decreased oxygen levels GO:0036293 58 0.040
Fly
response to organic substance GO:0010033 284 0.040
positive regulation of neuron differentiation GO:0045666 26 0.040
antimicrobial peptide biosynthetic process GO:0002777 38 0.040
regulation of axon extension GO:0030516 8 0.039
cell migration GO:0016477 238 0.038
regulation of axon extension involved in axon guidance GO:0048841 4 0.038
brain morphogenesis GO:0048854 16 0.038
Fly
regulation of response to biotic stimulus GO:0002831 63 0.038
negative regulation of programmed cell death GO:0043069 72 0.037
response to wounding GO:0009611 94 0.037
negative regulation of cell cycle GO:0045786 116 0.037
axon extension GO:0048675 32 0.037
hematopoietic or lymphoid organ development GO:0048534 57 0.037
Rat
positive regulation of transferase activity GO:0051347 26 0.037
Zebrafish
regulation of glial cell proliferation GO:0060251 11 0.036
negative regulation of cell division GO:0051782 17 0.036
regulation of production of molecular mediator of immune response GO:0002700 44 0.035
i kappab phosphorylation GO:0007252 3 0.035
neuroepithelial cell differentiation GO:0060563 6 0.034
negative regulation of neuron differentiation GO:0045665 16 0.034
Mouse Rat
regulation of localization GO:0032879 275 0.032
neuron migration GO:0001764 5 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
cell motility GO:0048870 251 0.031
regulation of phosphorylation GO:0042325 147 0.031
Zebrafish Mouse
negative regulation of response to stimulus GO:0048585 258 0.031
malpighian tubule development GO:0072002 64 0.031
antimicrobial peptide production GO:0002775 46 0.031
neural retina development GO:0003407 4 0.030
lateral inhibition GO:0046331 206 0.030
dedifferentiation GO:0043696 2 0.029
camera type eye morphogenesis GO:0048593 2 0.029
peptide metabolic process GO:0006518 80 0.029
positive regulation of organelle organization GO:0010638 65 0.029
Fly
regulation of reproductive process GO:2000241 54 0.027
reproductive behavior GO:0019098 122 0.027
negative regulation of cellular component organization GO:0051129 108 0.026
positive regulation of phosphorylation GO:0042327 87 0.026
Zebrafish Mouse
cell death GO:0008219 279 0.026
retina development in camera type eye GO:0060041 4 0.026
positive regulation of neuroblast proliferation GO:0002052 7 0.026
Fly
asymmetric cell division GO:0008356 37 0.025
defense response to other organism GO:0098542 225 0.025
neuroblast division GO:0055057 35 0.025
cellular amide metabolic process GO:0043603 80 0.024
regulation of histone deacetylation GO:0031063 2 0.024
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.024
cell recognition GO:0008037 102 0.024
bolwig s organ morphogenesis GO:0001746 8 0.024
chemotaxis GO:0006935 249 0.024
establishment of proximal distal cell polarity GO:0022606 4 0.024
programmed cell death GO:0012501 257 0.024
regulation of cell death GO:0010941 173 0.023
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.023
muscle cell development GO:0055001 50 0.022
dna metabolic process GO:0006259 227 0.022
production of molecular mediator of immune response GO:0002440 46 0.022
developmental growth involved in morphogenesis GO:0060560 65 0.022
regulation of transferase activity GO:0051338 58 0.022
Zebrafish
somatic stem cell maintenance GO:0035019 14 0.022
imaginal disc derived leg morphogenesis GO:0007480 80 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
Zebrafish Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
digestive system development GO:0055123 149 0.021
response to fungus GO:0009620 50 0.021
amide biosynthetic process GO:0043604 42 0.021
chromosome organization GO:0051276 360 0.021
growth GO:0040007 359 0.021
positive regulation of protein phosphorylation GO:0001934 34 0.020
Zebrafish Mouse
regulation of axonogenesis GO:0050770 32 0.020
circadian behavior GO:0048512 76 0.020
positive regulation of programmed cell death GO:0043068 62 0.020
limb morphogenesis GO:0035108 1 0.019
death GO:0016265 284 0.018
muscle tissue development GO:0060537 30 0.018
positive regulation of synapse assembly GO:0051965 29 0.018
negative regulation of organelle organization GO:0010639 56 0.018
regulation of response to external stimulus GO:0032101 115 0.018
oenocyte development GO:0007438 8 0.018
defense response GO:0006952 300 0.018
peptide biosynthetic process GO:0043043 42 0.018
establishment of planar polarity GO:0001736 87 0.017
striated muscle cell differentiation GO:0051146 90 0.017
cellular response to radiation GO:0071478 52 0.017
regulation of programmed cell death GO:0043067 152 0.017
regulation of dendrite development GO:0050773 37 0.016
regulation of multi organism process GO:0043900 131 0.016
sensory perception GO:0007600 196 0.016
ectodermal placode development GO:0071696 4 0.016
cell type specific apoptotic process GO:0097285 38 0.016
endocytosis GO:0006897 310 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
larval development GO:0002164 104 0.016
regulation of jak stat cascade GO:0046425 43 0.016
Mouse
macromolecule catabolic process GO:0009057 161 0.016
regulation of axon guidance GO:1902667 10 0.015
positive regulation of protein deacetylation GO:0090312 2 0.015
positive regulation of apoptotic process GO:0043065 47 0.015
wound healing GO:0042060 75 0.015
regulation of cellular component size GO:0032535 98 0.015
mitotic cell cycle checkpoint GO:0007093 88 0.014
regulation of growth GO:0040008 233 0.014
limb development GO:0060173 1 0.014
immune effector process GO:0002252 98 0.014
rhythmic behavior GO:0007622 76 0.014
establishment of ommatidial planar polarity GO:0042067 49 0.014
positive regulation of histone deacetylation GO:0031065 2 0.014
proteolysis GO:0006508 192 0.013
protein transport GO:0015031 155 0.013
regulation of oviposition GO:0046662 14 0.013
response to oxygen containing compound GO:1901700 200 0.013
meiotic cell cycle process GO:1903046 132 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
Mouse
leg disc morphogenesis GO:0007478 80 0.013
organelle localization GO:0051640 148 0.013
response to alcohol GO:0097305 95 0.013

HLHmbeta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.831
Human
bone disease DOID:0080001 0 0.831
Human
disease of anatomical entity DOID:7 0 0.831
Human
dysostosis DOID:1934 0 0.831
Human
musculoskeletal system disease DOID:17 0 0.831
Human
connective tissue disease DOID:65 0 0.831
Human
spondylocostal dysostosis DOID:0050568 0 0.717
Human
cardiovascular system disease DOID:1287 0 0.014