Drosophila melanogaster

66 known processes

Sld5 (Dmel_CG14549)

CG14549 gene product from transcript CG14549-RA

(Aliases: CG14549,Dmel\CG14549,anon-WO0172774.61)

Sld5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna conformation change GO:0071103 105 0.612
negative regulation of cellular metabolic process GO:0031324 382 0.453
cell cell signaling involved in cell fate commitment GO:0045168 210 0.187
morphogenesis of an epithelium GO:0002009 276 0.153
microtubule organizing center organization GO:0031023 168 0.146
centrosome organization GO:0051297 163 0.145
homeostatic process GO:0042592 199 0.129
regulation of cell cycle process GO:0010564 181 0.107
dna packaging GO:0006323 91 0.104
single organism behavior GO:0044708 391 0.096
dna duplex unwinding GO:0032508 16 0.093
cell division GO:0051301 248 0.086
rrna processing GO:0006364 3 0.075
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.074
immune system process GO:0002376 347 0.068
regulation of cell cycle GO:0051726 291 0.063
chromosome condensation GO:0030261 41 0.062
growth GO:0040007 359 0.056
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.055
developmental growth GO:0048589 280 0.053
digestive system development GO:0055123 149 0.051
urogenital system development GO:0001655 72 0.051
nuclear division GO:0000280 332 0.048
dna metabolic process GO:0006259 227 0.048
lateral inhibition GO:0046331 206 0.047
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.046
positive regulation of cellular component organization GO:0051130 156 0.046
renal tubule development GO:0061326 64 0.046
cell fate determination GO:0001709 91 0.045
spindle organization GO:0007051 253 0.045
malpighian tubule development GO:0072002 64 0.044
centrosome duplication GO:0051298 121 0.044
stem cell division GO:0017145 69 0.043
defense response GO:0006952 300 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.042
body morphogenesis GO:0010171 2 0.041
dna repair GO:0006281 54 0.040
Yeast
positive regulation of intracellular protein transport GO:0090316 30 0.040
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.038
nucleoside triphosphate metabolic process GO:0009141 120 0.038
chromatin assembly or disassembly GO:0006333 52 0.038
cell cycle phase transition GO:0044770 140 0.038
neuron fate commitment GO:0048663 50 0.037
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
protein complex biogenesis GO:0070271 201 0.036
organelle fission GO:0048285 340 0.036
organonitrogen compound metabolic process GO:1901564 318 0.036
regulation of cell morphogenesis GO:0022604 163 0.036
organelle assembly GO:0070925 198 0.036
glycosyl compound catabolic process GO:1901658 112 0.036
nucleoside metabolic process GO:0009116 127 0.035
negative regulation of gene expression GO:0010629 387 0.034
meiotic nuclear division GO:0007126 151 0.034
stem cell development GO:0048864 79 0.034
positive regulation of rna biosynthetic process GO:1902680 266 0.033
positive regulation of rna metabolic process GO:0051254 271 0.032
regulation of proteasomal protein catabolic process GO:0061136 39 0.032
cytokinesis GO:0000910 90 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.032
single organism cellular localization GO:1902580 180 0.031
spindle assembly involved in mitosis GO:0090307 50 0.031
mitotic cell cycle phase transition GO:0044772 138 0.031
imaginal disc growth GO:0007446 37 0.031
intracellular signal transduction GO:0035556 300 0.031
response to abiotic stimulus GO:0009628 341 0.030
negative regulation of cellular catabolic process GO:0031330 34 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.030
negative regulation of cell death GO:0060548 81 0.030
positive regulation of nucleic acid templated transcription GO:1903508 266 0.030
organonitrogen compound catabolic process GO:1901565 128 0.030
regulation of phosphate metabolic process GO:0019220 210 0.029
organelle fusion GO:0048284 46 0.029
translational initiation GO:0006413 11 0.028
positive regulation of protein transport GO:0051222 37 0.028
dendrite morphogenesis GO:0048813 199 0.028
regulation of mitotic cell cycle phase transition GO:1901990 130 0.027
nucleoside phosphate catabolic process GO:1901292 110 0.027
compound eye photoreceptor cell differentiation GO:0001751 140 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.026
anterior posterior pattern specification GO:0009952 136 0.026
neuroblast proliferation GO:0007405 74 0.026
proteasomal protein catabolic process GO:0010498 59 0.026
negative regulation of chromosome segregation GO:0051985 14 0.026
renal system development GO:0072001 72 0.026
embryonic hindgut morphogenesis GO:0048619 48 0.026
gene silencing GO:0016458 138 0.025
regulation of cell cycle g1 s phase transition GO:1902806 23 0.024
organ growth GO:0035265 56 0.024
centrosome cycle GO:0007098 137 0.024
rhythmic behavior GO:0007622 76 0.024
positive regulation of cell cycle process GO:0090068 28 0.023
purine nucleoside triphosphate metabolic process GO:0009144 119 0.023
positive regulation of developmental growth GO:0048639 62 0.023
organic substance catabolic process GO:1901575 308 0.023
organophosphate metabolic process GO:0019637 195 0.022
purine containing compound metabolic process GO:0072521 155 0.022
chromosome organization GO:0051276 360 0.022
regulation of anatomical structure morphogenesis GO:0022603 242 0.021
gland development GO:0048732 191 0.021
positive regulation of growth GO:0045927 75 0.021
negative regulation of rna biosynthetic process GO:1902679 240 0.021
establishment or maintenance of cell polarity GO:0007163 167 0.021
mitotic nuclear division GO:0007067 213 0.021
regulation of growth GO:0040008 233 0.021
small gtpase mediated signal transduction GO:0007264 88 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
neural precursor cell proliferation GO:0061351 75 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.020
negative regulation of chromosome organization GO:2001251 19 0.020
negative regulation of catabolic process GO:0009895 36 0.020
purine nucleoside metabolic process GO:0042278 127 0.020
stem cell proliferation GO:0072089 88 0.020
regulation of establishment of protein localization GO:0070201 61 0.020
ribonucleoside catabolic process GO:0042454 112 0.019
compound eye development GO:0048749 307 0.019
regulation of organelle organization GO:0033043 196 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
reproductive behavior GO:0019098 122 0.019
female meiotic division GO:0007143 70 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
regulation of neuron projection development GO:0010975 69 0.019
phosphorylation GO:0016310 294 0.019
negative regulation of cellular component organization GO:0051129 108 0.018
asymmetric stem cell division GO:0098722 49 0.018
regulation of protein metabolic process GO:0051246 256 0.018
spindle assembly GO:0051225 80 0.018
catecholamine biosynthetic process GO:0042423 3 0.018
chemosensory behavior GO:0007635 106 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
renal tubule morphogenesis GO:0061333 44 0.018
dna dependent dna replication GO:0006261 17 0.017
Yeast
olfactory behavior GO:0042048 97 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
dna replication GO:0006260 48 0.017
Yeast
protein transport GO:0015031 155 0.017
circadian rhythm GO:0007623 105 0.016
molting cycle GO:0042303 56 0.016
negative regulation of nervous system development GO:0051961 92 0.016
g1 s transition of mitotic cell cycle GO:0000082 31 0.016
regulation of protein catabolic process GO:0042176 55 0.016
cell death GO:0008219 279 0.016
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.016
positive regulation of nervous system development GO:0051962 69 0.016
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.016
regulation of localization GO:0032879 275 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
response to monosaccharide GO:0034284 4 0.016
cell proliferation GO:0008283 299 0.016
regulation of cell shape GO:0008360 113 0.016
morphogenesis of embryonic epithelium GO:0016331 94 0.015
death GO:0016265 284 0.015
lymph gland development GO:0048542 28 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
muscle tissue morphogenesis GO:0060415 2 0.015
meiotic cell cycle GO:0051321 171 0.015
positive regulation of signaling GO:0023056 243 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
immune system development GO:0002520 57 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
muscle structure development GO:0061061 224 0.015
negative regulation of gene expression epigenetic GO:0045814 77 0.015
single organism biosynthetic process GO:0044711 206 0.014
epithelial cell differentiation GO:0030855 322 0.014
cellular macromolecule localization GO:0070727 220 0.014
ribonucleoside monophosphate metabolic process GO:0009161 51 0.014
chromatin silencing GO:0006342 76 0.014
organic acid metabolic process GO:0006082 103 0.014
cellular protein catabolic process GO:0044257 83 0.014
purine nucleoside monophosphate metabolic process GO:0009126 50 0.014
phenol containing compound biosynthetic process GO:0046189 6 0.014
developmental maturation GO:0021700 172 0.014
mitotic sister chromatid separation GO:0051306 30 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
multicellular organismal homeostasis GO:0048871 41 0.014
axis specification GO:0009798 167 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
establishment of protein localization GO:0045184 163 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.014
positive regulation of cell development GO:0010720 61 0.013
catechol containing compound biosynthetic process GO:0009713 3 0.013
mesenchymal cell development GO:0014031 1 0.013
asymmetric neuroblast division GO:0055059 33 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
single organism catabolic process GO:0044712 228 0.013
jak stat cascade GO:0007259 49 0.013
synaptic transmission GO:0007268 288 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
chromatin organization GO:0006325 207 0.013
mitotic spindle organization GO:0007052 220 0.013
meiotic spindle organization GO:0000212 36 0.013
regulation of behavior GO:0050795 75 0.013
protein dna complex assembly GO:0065004 63 0.013
hindgut morphogenesis GO:0007442 58 0.012
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.012
regulation of nervous system development GO:0051960 248 0.012
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.012
mitotic cell cycle embryonic GO:0045448 38 0.012
protein localization to organelle GO:0033365 82 0.012
protein catabolic process GO:0030163 101 0.012
anion transport GO:0006820 41 0.012
mating GO:0007618 120 0.012
purine nucleoside biosynthetic process GO:0042451 3 0.012
chemical homeostasis GO:0048878 92 0.012
regulation of catabolic process GO:0009894 170 0.012
positive regulation of cell communication GO:0010647 250 0.012
spindle checkpoint GO:0031577 11 0.012
stem cell differentiation GO:0048863 117 0.012
regulation of protein localization GO:0032880 76 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
positive regulation of transport GO:0051050 92 0.012
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.012
endomembrane system organization GO:0010256 119 0.011
cytoplasm organization GO:0007028 64 0.011
compound eye morphogenesis GO:0001745 249 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
tripartite regional subdivision GO:0007351 103 0.011
protein modification process GO:0036211 438 0.011
eye morphogenesis GO:0048592 260 0.011
mesoderm development GO:0007498 78 0.011
taxis GO:0042330 304 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
dendrite development GO:0016358 204 0.011
reproductive system development GO:0061458 74 0.011
cell growth GO:0016049 108 0.011
regulation of chromatin silencing GO:0031935 36 0.011
regulation of heart morphogenesis GO:2000826 3 0.011
regulation of immune system process GO:0002682 176 0.011
negative regulation of developmental process GO:0051093 201 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
regulation of mitotic sister chromatid segregation GO:0033047 28 0.011
larval behavior GO:0030537 42 0.010
somatic stem cell division GO:0048103 37 0.010
detection of external stimulus GO:0009581 66 0.010
embryonic axis specification GO:0000578 107 0.010
appendage development GO:0048736 401 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
nucleotide catabolic process GO:0009166 109 0.010
purine containing compound catabolic process GO:0072523 112 0.010
small molecule metabolic process GO:0044281 305 0.010
purine ribonucleoside biosynthetic process GO:0046129 3 0.010
centriole replication GO:0007099 24 0.010
cardiovascular system development GO:0072358 82 0.010
pharynx development GO:0060465 1 0.010
protein complex assembly GO:0006461 200 0.010

Sld5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.031
disease of anatomical entity DOID:7 0 0.031
sensory system disease DOID:0050155 0 0.019
nervous system disease DOID:863 0 0.019
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
cardiovascular system disease DOID:1287 0 0.012