Drosophila melanogaster

145 known processes

ey (Dmel_CG1464)

eyeless

(Aliases: eye,pax6,l(4)102CDr,Ey/Pax6,l(4)102CDh,Dmel\CG1464,Pax6,EY,Ey,Pax-6,DPax-6,CG1464,l(4)33,EYEL)

ey biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axon guidance GO:0007411 233 0.996
Mouse
central nervous system development GO:0007417 201 0.992
compound eye development GO:0048749 307 0.954
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.953
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.946
axonogenesis GO:0007409 290 0.941
Mouse
single organism behavior GO:0044708 391 0.922
negative regulation of cellular biosynthetic process GO:0031327 277 0.904
Mouse Fly
growth GO:0040007 359 0.896
transcription from rna polymerase ii promoter GO:0006366 368 0.894
photoreceptor cell fate commitment GO:0046552 41 0.889
brain development GO:0007420 120 0.882
camera type eye photoreceptor cell differentiation GO:0060219 2 0.878
Zebrafish
regulation of cell differentiation GO:0045595 302 0.874
Mouse Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.869
Mouse Fly
motor neuron axon guidance GO:0008045 58 0.865
embryonic organ development GO:0048568 50 0.864
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.845
positive regulation of rna metabolic process GO:0051254 271 0.844
negative regulation of cellular metabolic process GO:0031324 382 0.835
Mouse Fly
retinal cone cell differentiation GO:0042670 2 0.835
Zebrafish
negative regulation of rna metabolic process GO:0051253 251 0.833
Mouse Fly
appendage development GO:0048736 401 0.830
Fly
positive regulation of gene expression GO:0010628 290 0.820
imaginal disc derived appendage morphogenesis GO:0035114 395 0.820
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.807
mushroom body development GO:0016319 70 0.795
embryonic morphogenesis GO:0048598 206 0.777
Mouse
axon development GO:0061564 297 0.769
Mouse
dendrite guidance GO:0070983 21 0.767
positive regulation of developmental process GO:0051094 143 0.759
eye antennal disc development GO:0035214 60 0.743
Fly
neuron projection guidance GO:0097485 241 0.740
Mouse
antennal development GO:0007469 25 0.738
Fly
positive regulation of epithelial cell differentiation GO:0030858 1 0.734
Mouse
leg disc development GO:0035218 92 0.722
circadian rhythm GO:0007623 105 0.713
taxis GO:0042330 304 0.711
Mouse
appendage morphogenesis GO:0035107 397 0.688
Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.679
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.678
positive regulation of growth GO:0045927 75 0.672
head development GO:0060322 135 0.661
neuron fate specification GO:0048665 12 0.643
circadian behavior GO:0048512 76 0.640
imaginal disc derived wing morphogenesis GO:0007476 337 0.635
negative regulation of rna biosynthetic process GO:1902679 240 0.627
Mouse Fly
cell motility GO:0048870 251 0.625
positive regulation of macromolecule metabolic process GO:0010604 405 0.621
developmental growth GO:0048589 280 0.609
forebrain development GO:0030900 2 0.594
Zebrafish Mouse Rat
regulation of growth GO:0040008 233 0.582
retina morphogenesis in camera type eye GO:0060042 2 0.581
Zebrafish
regulation of r7 cell differentiation GO:0045676 15 0.565
regionalization GO:0003002 416 0.550
Zebrafish Mouse
photoreceptor cell fate specification GO:0043704 9 0.547
cell fate specification GO:0001708 71 0.544
chemotaxis GO:0006935 249 0.544
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.536
positive regulation of rna biosynthetic process GO:1902680 266 0.534
imaginal disc derived appendage development GO:0048737 399 0.526
Fly
photoreceptor cell differentiation GO:0046530 170 0.504
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.497
Mouse Fly
death GO:0016265 284 0.492
regulation of epithelial cell proliferation GO:0050678 4 0.489
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 27 0.465
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.457
negative regulation of signaling GO:0023057 219 0.452
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.449
Mouse Fly
regulation of organ morphogenesis GO:2000027 78 0.442
reproductive system development GO:0061458 74 0.436
positive regulation of nervous system development GO:0051962 69 0.432
Mouse Rat
negative regulation of biosynthetic process GO:0009890 277 0.428
Mouse Fly
cellular response to growth factor stimulus GO:0071363 30 0.419
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.418
multi multicellular organism process GO:0044706 123 0.418
digestive tract development GO:0048565 149 0.410
hair cell differentiation GO:0035315 47 0.406
kidney development GO:0001822 3 0.384
positive regulation of biosynthetic process GO:0009891 316 0.374
skin development GO:0043588 65 0.359
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.357
gastrulation GO:0007369 70 0.348
programmed cell death GO:0012501 257 0.345
photoreceptor cell axon guidance GO:0072499 23 0.341
cellular response to endogenous stimulus GO:0071495 80 0.324
Rat
regulation of cell fate commitment GO:0010453 29 0.315
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.311
Mouse Fly
positive regulation of developmental growth GO:0048639 62 0.309
regulation of programmed cell death GO:0043067 152 0.307
apoptotic process GO:0006915 159 0.306
rhythmic process GO:0048511 106 0.305
actin filament based process GO:0030029 220 0.304
localization of cell GO:0051674 257 0.301
cellular response to chemical stimulus GO:0070887 199 0.287
Rat
positive regulation of nucleic acid templated transcription GO:1903508 266 0.287
sensory organ morphogenesis GO:0090596 260 0.282
eye photoreceptor cell differentiation GO:0001754 145 0.278
Zebrafish Mouse
response to growth factor GO:0070848 31 0.273
Rat
regulation of neuron projection development GO:0010975 69 0.272
Rat
kidney epithelium development GO:0072073 3 0.271
developmental maturation GO:0021700 172 0.262
regulation of catalytic activity GO:0050790 185 0.260
camera type eye development GO:0043010 4 0.256
Human Zebrafish Mouse Rat
wing disc morphogenesis GO:0007472 344 0.256
developmental growth involved in morphogenesis GO:0060560 65 0.246
regulation of heart morphogenesis GO:2000826 3 0.245
segmentation GO:0035282 207 0.245
dendrite development GO:0016358 204 0.237
cellular response to organic substance GO:0071310 132 0.233
Rat
regulation of protein metabolic process GO:0051246 256 0.230
Mouse
chaeta morphogenesis GO:0008407 42 0.230
neural retina development GO:0003407 4 0.229
Zebrafish
sex differentiation GO:0007548 81 0.226
positive regulation of cell proliferation GO:0008284 47 0.217
Zebrafish Mouse
organic substance catabolic process GO:1901575 308 0.217
retina development in camera type eye GO:0060041 4 0.213
Zebrafish Mouse Rat
compound eye morphogenesis GO:0001745 249 0.212
reproductive behavior GO:0019098 122 0.212
negative regulation of neuron death GO:1901215 18 0.209
biological adhesion GO:0022610 138 0.207
regulation of neurogenesis GO:0050767 158 0.207
Mouse Rat
cellular response to oxygen containing compound GO:1901701 79 0.201
Rat
response to peptide hormone GO:0043434 29 0.201
Rat
camera type eye morphogenesis GO:0048593 2 0.194
Human Zebrafish Mouse
antennal morphogenesis GO:0048800 14 0.192
mesenchymal cell differentiation GO:0048762 1 0.191
Rat
cellular protein modification process GO:0006464 438 0.190
Mouse
regulation of photoreceptor cell differentiation GO:0046532 34 0.189
compound eye photoreceptor cell differentiation GO:0001751 140 0.189
kidney morphogenesis GO:0060993 3 0.183
epidermal cell differentiation GO:0009913 51 0.181
Mouse
establishment of localization in cell GO:0051649 402 0.181
Mouse Rat
regulation of nervous system development GO:0051960 248 0.180
Mouse Rat
regulation of developmental growth GO:0048638 174 0.180
retinal ganglion cell axon guidance GO:0031290 12 0.176
response to endogenous stimulus GO:0009719 119 0.173
Rat
locomotor rhythm GO:0045475 56 0.173
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.167
Mouse Fly
dendrite morphogenesis GO:0048813 199 0.162
morphogenesis of an epithelium GO:0002009 276 0.162
embryonic pattern specification GO:0009880 174 0.161
tissue morphogenesis GO:0048729 297 0.161
Zebrafish
regulation of multicellular organismal development GO:2000026 414 0.159
Mouse Rat
negative regulation of response to stimulus GO:0048585 258 0.159
regulation of proteolysis GO:0030162 87 0.155
central complex development GO:0048036 9 0.155
negative regulation of nucleic acid templated transcription GO:1903507 240 0.154
Mouse Fly
cell migration GO:0016477 238 0.149
positive regulation of protein metabolic process GO:0051247 128 0.149
positive regulation of endopeptidase activity GO:0010950 26 0.149
outflow tract morphogenesis GO:0003151 4 0.144
muscle organ development GO:0007517 127 0.141
neuron fate commitment GO:0048663 50 0.140
response to organic substance GO:0010033 284 0.138
Rat
immune system process GO:0002376 347 0.137
heart development GO:0007507 82 0.137
response to external biotic stimulus GO:0043207 293 0.134
eye photoreceptor cell development GO:0042462 81 0.134
Mouse
multi organism reproductive behavior GO:0044705 121 0.131
muscle structure development GO:0061061 224 0.130
torso signaling pathway GO:0008293 21 0.129
response to organic cyclic compound GO:0014070 89 0.128
regulation of cell projection organization GO:0031344 92 0.127
Rat
antennal joint development GO:0048098 5 0.126
embryonic development via the syncytial blastoderm GO:0001700 148 0.126
positive regulation of axonogenesis GO:0050772 2 0.126
cell death GO:0008219 279 0.126
response to lipid GO:0033993 38 0.125
Rat
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.122
female sex differentiation GO:0046660 20 0.122
nephron morphogenesis GO:0072028 3 0.120
positive regulation of axon guidance GO:1902669 1 0.119
negative regulation of multicellular organismal process GO:0051241 142 0.119
Mouse
protein modification process GO:0036211 438 0.118
Mouse
proteolysis GO:0006508 192 0.117
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.116
telencephalon development GO:0021537 2 0.115
Mouse Rat
imaginal disc derived leg segmentation GO:0036011 26 0.115
compound eye photoreceptor development GO:0042051 78 0.115
regulation of endopeptidase activity GO:0052548 36 0.115
cell adhesion GO:0007155 136 0.115
single organism intracellular transport GO:1902582 207 0.114
formation of organ boundary GO:0010160 30 0.114
embryo development ending in birth or egg hatching GO:0009792 152 0.105
Mouse
regulation of epithelial cell differentiation GO:0030856 4 0.105
Mouse
epithelial cell development GO:0002064 274 0.105
Human Mouse Rat
molting cycle GO:0042303 56 0.104
nephron tubule morphogenesis GO:0072078 3 0.104
molting cycle chitin based cuticle GO:0007591 56 0.103
positive regulation of multicellular organismal process GO:0051240 143 0.102
reproductive structure development GO:0048608 74 0.101
regulation of circadian rhythm GO:0042752 49 0.101
nephron tubule development GO:0072080 3 0.099
regulation of apoptotic process GO:0042981 130 0.098
eye development GO:0001654 323 0.097
r7 cell differentiation GO:0045466 43 0.097
phosphorylation GO:0016310 294 0.096
Mouse
cellular response to lipid GO:0071396 20 0.095
Rat
negative regulation of transcription dna templated GO:0045892 237 0.094
Mouse Fly
heart morphogenesis GO:0003007 32 0.094
secretion by cell GO:0032940 101 0.094
Rat
regulation of insulin like growth factor receptor signaling pathway GO:0043567 3 0.092
locomotory behavior GO:0007626 176 0.090
tube development GO:0035295 244 0.090
Mouse
regulation of axon extension involved in axon guidance GO:0048841 4 0.089
digestive system development GO:0055123 149 0.087
nephron epithelium development GO:0072009 3 0.086
mesoderm development GO:0007498 78 0.086
regulation of neuron differentiation GO:0045664 103 0.085
Mouse Rat
development of primary sexual characteristics GO:0045137 50 0.085
positive regulation of cell communication GO:0010647 250 0.084
Rat
organic substance transport GO:0071702 257 0.083
Rat
mesodermal cell fate specification GO:0007501 2 0.083
protein complex biogenesis GO:0070271 201 0.083
oxidation reduction process GO:0055114 123 0.080
leg disc morphogenesis GO:0007478 80 0.079
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.079
exocrine system development GO:0035272 162 0.078
Mouse
response to hormone GO:0009725 45 0.078
Rat
single organism cellular localization GO:1902580 180 0.077
Mouse
determination of imaginal disc primordium GO:0007445 11 0.077
response to peptide GO:1901652 29 0.077
Rat
rhythmic behavior GO:0007622 76 0.076
regulation of localization GO:0032879 275 0.075
Mouse Rat
multicellular organismal reproductive behavior GO:0033057 110 0.074
regulation of cell death GO:0010941 173 0.074
mesenchyme development GO:0060485 9 0.073
Rat
appendage segmentation GO:0035285 26 0.072
small molecule metabolic process GO:0044281 305 0.072
negative regulation of cell death GO:0060548 81 0.071
positive regulation of molecular function GO:0044093 136 0.070
regulation of cell development GO:0060284 215 0.067
Mouse Rat
specification of organ identity GO:0010092 3 0.066
synapse organization GO:0050808 196 0.066
response to reactive oxygen species GO:0000302 24 0.065
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.064
regulation of molecular function GO:0065009 217 0.063
regulation of intracellular signal transduction GO:1902531 236 0.063
genital disc development GO:0035215 44 0.063
regulation of catabolic process GO:0009894 170 0.062
spermatogenesis GO:0007283 200 0.062
crystal cell differentiation GO:0042688 7 0.061
cellular macromolecule localization GO:0070727 220 0.061
Mouse
regulation of dendrite morphogenesis GO:0048814 28 0.060
cellular macromolecular complex assembly GO:0034622 153 0.060
enzyme linked receptor protein signaling pathway GO:0007167 179 0.059
ion transport GO:0006811 145 0.059
mating GO:0007618 120 0.058
positive regulation of cellular catabolic process GO:0031331 95 0.058
cellular catabolic process GO:0044248 372 0.058
epidermis development GO:0008544 65 0.058
Mouse
positive regulation of cellular component organization GO:0051130 156 0.058
regulation of synapse assembly GO:0051963 94 0.056
optic placode formation GO:0001743 4 0.056
wing disc pattern formation GO:0035222 66 0.056
regulation of protein modification process GO:0031399 112 0.056
Mouse
connective tissue development GO:0061448 3 0.055
renal system development GO:0072001 72 0.055
neuron projection extension GO:1990138 32 0.055
protein modification by small protein conjugation or removal GO:0070647 106 0.055
immune response GO:0006955 246 0.054
positive regulation of hydrolase activity GO:0051345 78 0.054
positive regulation of peptidase activity GO:0010952 29 0.054
positive regulation of cell development GO:0010720 61 0.054
Mouse Rat
somatic muscle development GO:0007525 66 0.054
eye photoreceptor cell fate commitment GO:0042706 37 0.053
regulation of protein phosphorylation GO:0001932 64 0.053
Mouse
positive regulation of retinal cell programmed cell death GO:0046670 9 0.053
male courtship behavior veined wing extension GO:0048065 22 0.053
negative regulation of programmed cell death GO:0043069 72 0.053
nephron development GO:0072006 3 0.052
positive regulation of catabolic process GO:0009896 105 0.051
regulation of cellular component biogenesis GO:0044087 201 0.051
regulation of axon guidance GO:1902667 10 0.051
negative regulation of nervous system development GO:0051961 92 0.050
Mouse
ovarian follicle cell development GO:0030707 248 0.050
regulation of phosphorus metabolic process GO:0051174 210 0.050
Mouse
synaptic growth at neuromuscular junction GO:0051124 119 0.049
regulation of anatomical structure size GO:0090066 163 0.049
negative regulation of growth GO:0045926 84 0.048
regulation of hydrolase activity GO:0051336 97 0.048
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.046
gland development GO:0048732 191 0.046
Mouse
positive regulation of response to stimulus GO:0048584 323 0.046
positive regulation of cell death GO:0010942 69 0.046
cranial nerve development GO:0021545 1 0.046
protein maturation GO:0051604 71 0.046
eye morphogenesis GO:0048592 260 0.045
cell recognition GO:0008037 102 0.044
cardioblast differentiation GO:0010002 20 0.044
imaginal disc derived leg morphogenesis GO:0007480 80 0.044
convergent extension GO:0060026 2 0.044
anatomical structure homeostasis GO:0060249 97 0.043
positive regulation of response to external stimulus GO:0032103 44 0.043
response to oxidative stress GO:0006979 86 0.043
cell growth GO:0016049 108 0.043
stem cell development GO:0048864 79 0.042
Rat
protein processing GO:0016485 68 0.042
response to fibroblast growth factor GO:0071774 10 0.042
Rat
urogenital system development GO:0001655 72 0.041
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.041
intracellular protein transport GO:0006886 104 0.041
posterior head segmentation GO:0035289 6 0.040
regulation of cell proliferation GO:0042127 163 0.040
Zebrafish Mouse
development of primary female sexual characteristics GO:0046545 12 0.039
response to oxygen containing compound GO:1901700 200 0.039
Rat
formation of anatomical boundary GO:0048859 37 0.039
Mouse
body morphogenesis GO:0010171 2 0.039
axis specification GO:0009798 167 0.038
Mouse
muscle cell differentiation GO:0042692 103 0.038
negative regulation of developmental process GO:0051093 201 0.038
Mouse
muscle cell fate commitment GO:0042693 14 0.038
organ formation GO:0048645 39 0.038
genital disc sexually dimorphic development GO:0035263 4 0.037
male mating behavior GO:0060179 70 0.037
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.037
muscle organ morphogenesis GO:0048644 7 0.037
wnt signaling pathway GO:0016055 98 0.036
response to nitrogen compound GO:1901698 90 0.036
Rat
negative regulation of neuron apoptotic process GO:0043524 14 0.036
regulation of cellular catabolic process GO:0031329 157 0.036
positive regulation of multicellular organism growth GO:0040018 21 0.036
response to organonitrogen compound GO:0010243 75 0.036
Rat
carboxylic acid metabolic process GO:0019752 92 0.036
regulation of peptidase activity GO:0052547 39 0.036
protein ubiquitination GO:0016567 70 0.035
response to extracellular stimulus GO:0009991 116 0.035
regulation of cell size GO:0008361 63 0.035
negative regulation of gene expression GO:0010629 387 0.035
Mouse Fly
anterior posterior axis specification GO:0009948 109 0.034
hematopoietic progenitor cell differentiation GO:0002244 1 0.034
cellular response to organonitrogen compound GO:0071417 36 0.034
Rat
developmental cell growth GO:0048588 52 0.034
optic lobe placode development GO:0001748 10 0.034
positive regulation of phosphorus metabolic process GO:0010562 139 0.034
cellular response to monosaccharide stimulus GO:0071326 2 0.033
Rat
apoptotic signaling pathway GO:0097190 27 0.033
negative regulation of apoptotic process GO:0043066 63 0.032
regulation of axonogenesis GO:0050770 32 0.032
trunk segmentation GO:0035290 8 0.032
neuron recognition GO:0008038 101 0.031
heart formation GO:0060914 6 0.031
regulation of imaginal disc derived wing size GO:0044719 20 0.031
female gonad development GO:0008585 12 0.030
cellular response to oxidative stress GO:0034599 28 0.030
optic lobe placode formation GO:0001744 4 0.030
male courtship behavior GO:0008049 63 0.030
regulation of phosphorylation GO:0042325 147 0.030
Mouse
positive regulation of apoptotic process GO:0043065 47 0.030
negative regulation of cell communication GO:0010648 223 0.030
lipid metabolic process GO:0006629 121 0.029
actin cytoskeleton organization GO:0030036 206 0.029
response to insulin GO:0032868 29 0.029
Rat
eye antennal disc morphogenesis GO:0007455 34 0.029
cardioblast cell fate commitment GO:0042684 14 0.028
macromolecule catabolic process GO:0009057 161 0.028
cell type specific apoptotic process GO:0097285 38 0.028
intracellular receptor signaling pathway GO:0030522 19 0.028
single organismal cell cell adhesion GO:0016337 45 0.028
molting cycle process GO:0022404 29 0.028
axon extension GO:0048675 32 0.028
cardioblast cell fate specification GO:0042685 9 0.027
response to hydrogen peroxide GO:0042542 11 0.027
positive regulation of cell differentiation GO:0045597 64 0.027
Mouse Rat
salivary gland development GO:0007431 162 0.027
Mouse
positive regulation of axon extension GO:0045773 2 0.027
male gamete generation GO:0048232 201 0.027
endocrine system development GO:0035270 5 0.026
Human Zebrafish Mouse Rat
positive regulation of phosphate metabolic process GO:0045937 139 0.026
cellular response to acid chemical GO:0071229 8 0.026
Rat
cell proliferation GO:0008283 299 0.026
Zebrafish Mouse Rat
male genitalia development GO:0030539 19 0.026
developmental induction GO:0031128 3 0.026
hindbrain development GO:0030902 2 0.026
Zebrafish Rat
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.025
cellular respiration GO:0045333 26 0.025
photoreceptor cell development GO:0042461 96 0.025
Mouse
mating behavior GO:0007617 106 0.025
organ induction GO:0001759 3 0.025
stem cell division GO:0017145 69 0.025
positive regulation of signal transduction GO:0009967 223 0.025
regulation of cell growth GO:0001558 43 0.025
negative regulation of neurogenesis GO:0050768 53 0.024
Mouse
response to abiotic stimulus GO:0009628 341 0.024
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.024
anterior posterior pattern specification GO:0009952 136 0.023
Zebrafish Mouse
catabolic process GO:0009056 409 0.023
inter male aggressive behavior GO:0002121 60 0.023
negative regulation of phosphate metabolic process GO:0045936 45 0.023
Mouse
axon extension involved in axon guidance GO:0048846 10 0.023
leg disc proximal distal pattern formation GO:0007479 9 0.023
protein modification by small protein conjugation GO:0032446 79 0.023
positive regulation of cell motility GO:2000147 3 0.022
Rat
skeletal muscle organ development GO:0060538 48 0.022
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.022
protein localization to organelle GO:0033365 82 0.022
Mouse
negative regulation of signal transduction GO:0009968 206 0.022
response to acid chemical GO:0001101 25 0.021
Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.021
regulation of synapse structure and activity GO:0050803 128 0.021
multi organism behavior GO:0051705 175 0.021
intracellular signal transduction GO:0035556 300 0.021
adult walking behavior GO:0007628 9 0.021
genitalia development GO:0048806 26 0.021
digestive tract morphogenesis GO:0048546 127 0.021
positive regulation of neuron differentiation GO:0045666 26 0.020
anterior malpighian tubule development GO:0061327 12 0.020
spinal cord development GO:0021510 1 0.020
Mouse Rat
imaginal disc pattern formation GO:0007447 91 0.020
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.020
gland morphogenesis GO:0022612 145 0.020
Mouse
protein transport GO:0015031 155 0.020
synapse assembly GO:0007416 143 0.019
neurological system process GO:0050877 358 0.019
tissue migration GO:0090130 155 0.019
cellular response to extracellular stimulus GO:0031668 64 0.019
response to wounding GO:0009611 94 0.019
Human
central nervous system neuron differentiation GO:0021953 8 0.019
Mouse
leg disc pattern formation GO:0035223 11 0.019
cognition GO:0050890 141 0.019
positive regulation of programmed cell death GO:0043068 62 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
brain morphogenesis GO:0048854 16 0.018
germ band extension GO:0007377 11 0.018
cellular response to hormone stimulus GO:0032870 44 0.018
Rat
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.018
vesicle mediated transport GO:0016192 381 0.018
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.018
Rat
chaeta development GO:0022416 97 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
central nervous system projection neuron axonogenesis GO:0021952 6 0.017
tube morphogenesis GO:0035239 191 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
Mouse
positive regulation of phosphorylation GO:0042327 87 0.017
negative regulation of catalytic activity GO:0043086 42 0.017
response to nutrient levels GO:0031667 114 0.017
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
response to hypoxia GO:0001666 53 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
oxoacid metabolic process GO:0043436 103 0.016
regulation of hormone levels GO:0010817 40 0.016
Rat
apoptotic process involved in morphogenesis GO:0060561 3 0.016
single organism catabolic process GO:0044712 228 0.016
feeding behavior GO:0007631 50 0.016
axon target recognition GO:0007412 16 0.016
negative regulation of peptide hormone secretion GO:0090278 1 0.016
activation of cysteine type endopeptidase activity GO:0097202 17 0.016
clypeo labral disc development GO:0035213 7 0.016
cellular response to nitrogen compound GO:1901699 51 0.016
Rat
regulation of phosphatase activity GO:0010921 3 0.015
cell maturation GO:0048469 144 0.015
carbohydrate metabolic process GO:0005975 82 0.015
determination of dorsal ventral asymmetry GO:0048262 3 0.015
negative regulation of epithelial cell proliferation GO:0050680 4 0.015
Mouse
positive regulation of catalytic activity GO:0043085 118 0.015
regulation of dendrite development GO:0050773 37 0.015
regulation of protein ubiquitination GO:0031396 22 0.015
spermatid development GO:0007286 98 0.015
regulation of muscle organ development GO:0048634 13 0.015
larval somatic muscle development GO:0007526 19 0.015
homeostatic process GO:0042592 199 0.014
Human Rat
regulation of cellular ketone metabolic process GO:0010565 3 0.014
glial cell migration GO:0008347 31 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
bolwig s organ development GO:0055034 8 0.014
regulation of cellular component size GO:0032535 98 0.014
muscle tissue morphogenesis GO:0060415 2 0.014
cellular response to external stimulus GO:0071496 66 0.014
carboxylic acid transport GO:0046942 18 0.013
regulation of protein catabolic process GO:0042176 55 0.013
adult behavior GO:0030534 137 0.013
epithelium migration GO:0090132 148 0.013
bolwig s organ morphogenesis GO:0001746 8 0.013
nephron epithelium morphogenesis GO:0072088 3 0.013
central nervous system segmentation GO:0035283 5 0.012
endocytosis GO:0006897 310 0.012
response to starvation GO:0042594 97 0.012
determination of bilateral symmetry GO:0009855 13 0.012
regulation of stem cell proliferation GO:0072091 40 0.012
Mouse
nitrogen compound transport GO:0071705 85 0.012
Rat
regulation of steroid metabolic process GO:0019218 2 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
response to transforming growth factor beta GO:0071559 18 0.012
regulation of neuron death GO:1901214 26 0.012

ey disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.359
Human
nervous system disease DOID:863 0 0.258
Human
sensory system disease DOID:0050155 0 0.089
Human
eye and adnexa disease DOID:1492 0 0.089
Human
eye disease DOID:5614 0 0.089
Human
cancer DOID:162 0 0.051
disease of cellular proliferation DOID:14566 0 0.051
organ system cancer DOID:0050686 0 0.051
musculoskeletal system disease DOID:17 0 0.014
retinal disease DOID:5679 0 0.013