Drosophila melanogaster

91 known processes

Usp7 (Dmel_CG1490)

ubiquitin-specific protease 7

(Aliases: Dmel\CG1490,CG1490,USP7)

Usp7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.637
single organism behavior GO:0044708 391 0.514
transcription from rna polymerase ii promoter GO:0006366 368 0.451
adult behavior GO:0030534 137 0.417
protein complex assembly GO:0006461 200 0.412
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.295
posttranscriptional gene silencing by rna GO:0035194 45 0.287
positive regulation of rna biosynthetic process GO:1902680 266 0.255
regulation of gene expression epigenetic GO:0040029 128 0.254
mitotic spindle organization GO:0007052 220 0.246
positive regulation of biosynthetic process GO:0009891 316 0.234
regulation of cell cycle GO:0051726 291 0.226
negative regulation of response to stimulus GO:0048585 258 0.213
positive regulation of transcription dna templated GO:0045893 266 0.208
locomotory behavior GO:0007626 176 0.203
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.196
positive regulation of gene expression GO:0010628 290 0.188
establishment of organelle localization GO:0051656 122 0.160
meiotic nuclear division GO:0007126 151 0.156
establishment of localization in cell GO:0051649 402 0.152
taxis GO:0042330 304 0.146
negative regulation of signal transduction GO:0009968 206 0.145
intracellular transport GO:0046907 228 0.141
response to light stimulus GO:0009416 124 0.137
posttranscriptional regulation of gene expression GO:0010608 145 0.134
Rat
nucleocytoplasmic transport GO:0006913 72 0.129
positive regulation of macromolecule metabolic process GO:0010604 405 0.126
gene silencing by mirna GO:0035195 22 0.125
adult locomotory behavior GO:0008344 76 0.123
rna processing GO:0006396 147 0.122
regulation of mitotic cell cycle GO:0007346 190 0.120
cellular protein modification process GO:0006464 438 0.117
regulation of multicellular organismal development GO:2000026 414 0.114
negative regulation of cellular biosynthetic process GO:0031327 277 0.111
cellular response to dna damage stimulus GO:0006974 223 0.109
Human
organelle localization GO:0051640 148 0.107
single organism intracellular transport GO:1902582 207 0.105
chemotaxis GO:0006935 249 0.103
negative regulation of gene expression GO:0010629 387 0.101
protein modification process GO:0036211 438 0.101
dendrite development GO:0016358 204 0.097
regulation of protein metabolic process GO:0051246 256 0.097
ncrna processing GO:0034470 30 0.096
negative regulation of signaling GO:0023057 219 0.093
positive regulation of rna metabolic process GO:0051254 271 0.093
axonogenesis GO:0007409 290 0.092
response to organic substance GO:0010033 284 0.091
regulation of cell cycle process GO:0010564 181 0.089
determination of adult lifespan GO:0008340 137 0.087
protein modification by small protein conjugation GO:0032446 79 0.077
rrna processing GO:0006364 3 0.074
negative regulation of cell communication GO:0010648 223 0.072
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.072
neuron projection guidance GO:0097485 241 0.072
regulation of intracellular signal transduction GO:1902531 236 0.067
negative regulation of wnt signaling pathway GO:0030178 28 0.066
posttranscriptional gene silencing GO:0016441 46 0.066
cell cycle phase transition GO:0044770 140 0.066
protein localization to nucleus GO:0034504 55 0.066
response to radiation GO:0009314 155 0.065
axon guidance GO:0007411 233 0.064
tissue morphogenesis GO:0048729 297 0.060
regulation of cellular protein metabolic process GO:0032268 243 0.059
positive regulation of proteolysis GO:0045862 52 0.055
gene silencing by rna GO:0031047 57 0.054
vesicle mediated transport GO:0016192 381 0.054
regulation of cellular response to stress GO:0080135 89 0.053
wing disc morphogenesis GO:0007472 344 0.053
neuroblast proliferation GO:0007405 74 0.051
cellular response to chemical stimulus GO:0070887 199 0.051
rna 3 end processing GO:0031123 45 0.049
neurological system process GO:0050877 358 0.048
methylation GO:0032259 47 0.048
protein ubiquitination GO:0016567 70 0.048
histone modification GO:0016570 106 0.048
organic substance catabolic process GO:1901575 308 0.048
positive regulation of nucleic acid templated transcription GO:1903508 266 0.045
microtubule polymerization or depolymerization GO:0031109 39 0.044
endocytosis GO:0006897 310 0.044
microtubule organizing center organization GO:0031023 168 0.044
mitotic cell cycle phase transition GO:0044772 138 0.044
homeostatic process GO:0042592 199 0.044
macromolecular complex assembly GO:0065003 256 0.043
positive regulation of signal transduction GO:0009967 223 0.042
regulation of nervous system development GO:0051960 248 0.042
organic cyclic compound catabolic process GO:1901361 168 0.042
growth GO:0040007 359 0.042
negative regulation of gene expression epigenetic GO:0045814 77 0.041
mrna metabolic process GO:0016071 124 0.041
positive regulation of cell communication GO:0010647 250 0.040
cellular macromolecular complex assembly GO:0034622 153 0.040
regulation of wnt signaling pathway GO:0030111 68 0.040
positive regulation of protein metabolic process GO:0051247 128 0.039
regulation of organelle organization GO:0033043 196 0.039
cytoplasmic transport GO:0016482 130 0.039
developmental maturation GO:0021700 172 0.039
cellular homeostasis GO:0019725 80 0.039
anatomical structure homeostasis GO:0060249 97 0.038
regulation of cellular amino acid metabolic process GO:0006521 0 0.038
positive regulation of response to stimulus GO:0048584 323 0.038
protein complex biogenesis GO:0070271 201 0.038
ncrna metabolic process GO:0034660 43 0.038
negative regulation of cellular metabolic process GO:0031324 382 0.037
cellular macromolecule localization GO:0070727 220 0.037
protein modification by small protein conjugation or removal GO:0070647 106 0.036
regulation of microtubule based process GO:0032886 49 0.036
response to abiotic stimulus GO:0009628 341 0.036
developmental growth GO:0048589 280 0.036
phagocytosis GO:0006909 215 0.035
aging GO:0007568 143 0.035
protein complex disassembly GO:0043241 36 0.034
regulation of growth GO:0040008 233 0.034
cellular component disassembly GO:0022411 46 0.034
cellular nitrogen compound catabolic process GO:0044270 165 0.034
imaginal disc derived wing morphogenesis GO:0007476 337 0.033
organelle fission GO:0048285 340 0.033
dna alkylation GO:0006305 4 0.032
protein import into nucleus GO:0006606 51 0.031
cellular protein localization GO:0034613 160 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.030
nucleus organization GO:0006997 45 0.030
negative regulation of nucleic acid templated transcription GO:1903507 240 0.030
positive regulation of cellular component organization GO:0051130 156 0.029
response to organic cyclic compound GO:0014070 89 0.029
regulation of bmp signaling pathway GO:0030510 23 0.029
protein targeting to nucleus GO:0044744 51 0.029
positive regulation of multicellular organismal process GO:0051240 143 0.029
regulation of cytoskeleton organization GO:0051493 89 0.029
oxoacid metabolic process GO:0043436 103 0.028
dendrite morphogenesis GO:0048813 199 0.028
embryonic morphogenesis GO:0048598 206 0.028
chromatin modification GO:0016568 147 0.028
establishment of protein localization to organelle GO:0072594 62 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.026
cellular carbohydrate metabolic process GO:0044262 22 0.026
cellular response to organic substance GO:0071310 132 0.026
establishment of spindle localization GO:0051293 22 0.026
mitotic cell cycle checkpoint GO:0007093 88 0.026
imaginal disc growth GO:0007446 37 0.026
compound eye morphogenesis GO:0001745 249 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
response to oxygen levels GO:0070482 59 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
rna polyadenylation GO:0043631 12 0.024
cell division GO:0051301 248 0.024
regulation of endopeptidase activity GO:0052548 36 0.023
eggshell formation GO:0030703 105 0.023
fertilization GO:0009566 26 0.023
bmp signaling pathway GO:0030509 27 0.023
regulation of circadian rhythm GO:0042752 49 0.023
regulation of developmental growth GO:0048638 174 0.023
telencephalon development GO:0021537 2 0.022
spindle organization GO:0007051 253 0.022
regulation of organ growth GO:0046620 42 0.022
mitotic nuclear division GO:0007067 213 0.022
axon cargo transport GO:0008088 29 0.022
cellular ketone metabolic process GO:0042180 24 0.022
nuclear transport GO:0051169 72 0.022
multicellular organismal aging GO:0010259 140 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
organic acid metabolic process GO:0006082 103 0.021
modification dependent macromolecule catabolic process GO:0043632 79 0.021
cellular response to abiotic stimulus GO:0071214 58 0.021
intracellular receptor signaling pathway GO:0030522 19 0.021
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.020
smoothened signaling pathway GO:0007224 49 0.020
positive regulation of immune response GO:0050778 63 0.020
peptidyl tyrosine phosphorylation GO:0018108 24 0.020
eye development GO:0001654 323 0.020
mrna processing GO:0006397 104 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
organ growth GO:0035265 56 0.019
rhythmic process GO:0048511 106 0.019
positive regulation of growth GO:0045927 75 0.019
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.019
amine metabolic process GO:0009308 12 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.019
peptidyl amino acid modification GO:0018193 105 0.019
response to decreased oxygen levels GO:0036293 58 0.019
molting cycle GO:0042303 56 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.018
protein transport GO:0015031 155 0.018
macromolecule catabolic process GO:0009057 161 0.018
cellular response to organic cyclic compound GO:0071407 32 0.018
negative regulation of neuron death GO:1901215 18 0.018
negative regulation of rna metabolic process GO:0051253 251 0.017
cellular response to radiation GO:0071478 52 0.017
protein polymerization GO:0051258 42 0.017
detection of light stimulus GO:0009583 58 0.017
actin cytoskeleton organization GO:0030036 206 0.017
alternative mrna splicing via spliceosome GO:0000380 60 0.017
positive regulation of cellular component biogenesis GO:0044089 80 0.017
immune system process GO:0002376 347 0.017
cellular protein complex disassembly GO:0043624 35 0.017
organic substance transport GO:0071702 257 0.017
establishment of mitotic spindle localization GO:0040001 17 0.016
mitotic spindle checkpoint GO:0071174 11 0.016
cellular response to oxidative stress GO:0034599 28 0.016
peptidyl lysine modification GO:0018205 57 0.016
dna repair GO:0006281 54 0.016
Human
nuclear division GO:0000280 332 0.016
neuron death GO:0070997 27 0.016
gene silencing GO:0016458 138 0.016
protein acetylation GO:0006473 39 0.016
actin filament based process GO:0030029 220 0.016
protein import GO:0017038 55 0.016
forebrain development GO:0030900 2 0.015
chromosome localization GO:0050000 20 0.015
regulation of response to oxidative stress GO:1902882 4 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
regulation of protein modification process GO:0031399 112 0.015
mesenchymal cell development GO:0014031 1 0.015
camera type eye development GO:0043010 4 0.015
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.014
muscle structure development GO:0061061 224 0.014
protein localization to organelle GO:0033365 82 0.014
protein localization GO:0008104 284 0.014
microtubule based transport GO:0010970 42 0.014
ovarian follicle cell development GO:0030707 248 0.014
protein targeting GO:0006605 64 0.014
endosomal transport GO:0016197 44 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.014
regulation of phosphatase activity GO:0010921 3 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
chromatin remodeling GO:0006338 72 0.014
jak stat cascade GO:0007259 49 0.013
regulation of cellular response to oxidative stress GO:1900407 4 0.013
regulation of neurogenesis GO:0050767 158 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
protein alkylation GO:0008213 43 0.013
protein k48 linked ubiquitination GO:0070936 3 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
regulation of proteolysis GO:0030162 87 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
wnt signaling pathway GO:0016055 98 0.013
learning GO:0007612 75 0.013
detection of stimulus GO:0051606 156 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
cellular response to light stimulus GO:0071482 37 0.013
spermatogenesis GO:0007283 200 0.013
synapse assembly GO:0007416 143 0.012
ncrna 3 end processing GO:0043628 17 0.012
establishment of protein localization GO:0045184 163 0.012
translation GO:0006412 69 0.012
dna methylation or demethylation GO:0044728 4 0.012
defense response to other organism GO:0098542 225 0.012
dna methylation GO:0006306 4 0.012
nuclear import GO:0051170 51 0.012
chromosome organization GO:0051276 360 0.012
regulation of cysteine type endopeptidase activity GO:2000116 27 0.012
regulation of protein localization GO:0032880 76 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
positive regulation of developmental process GO:0051094 143 0.012
axon development GO:0061564 297 0.012
regulation of localization GO:0032879 275 0.012
mesoderm development GO:0007498 78 0.011
regulation of nfat protein import into nucleus GO:0051532 16 0.011
covalent chromatin modification GO:0016569 106 0.011
negative regulation of organelle organization GO:0010639 56 0.011
regulation of anatomical structure size GO:0090066 163 0.011
aromatic compound catabolic process GO:0019439 166 0.011
chorion containing eggshell formation GO:0007304 105 0.011
regulation of nucleocytoplasmic transport GO:0046822 35 0.011
chromosome segregation GO:0007059 157 0.011
peptidyl tyrosine modification GO:0018212 24 0.011
negative regulation of smoothened signaling pathway GO:0045879 16 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.011
single organism cellular localization GO:1902580 180 0.011
cellular catabolic process GO:0044248 372 0.011
cell death GO:0008219 279 0.011
Rat
chromatin organization GO:0006325 207 0.011
intracellular protein transport GO:0006886 104 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
regulation of protein localization to nucleus GO:1900180 29 0.011
cellular protein complex assembly GO:0043623 71 0.011
macromolecule methylation GO:0043414 45 0.010
regulation of transport GO:0051049 181 0.010
catabolic process GO:0009056 409 0.010
cellular response to sterol depletion GO:0071501 3 0.010
oocyte microtubule cytoskeleton organization GO:0016325 35 0.010
response to endogenous stimulus GO:0009719 119 0.010
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.010
chaeta morphogenesis GO:0008407 42 0.010
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.010
regulation of gene silencing GO:0060968 63 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
response to oxidative stress GO:0006979 86 0.010
rna splicing via transesterification reactions GO:0000375 73 0.010
imaginal disc derived wing vein specification GO:0007474 48 0.010

Usp7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
nervous system disease DOID:863 0 0.018