Drosophila melanogaster

80 known processes

fw (Dmel_CG1500)

furrowed

(Aliases: fw-like,Dmel\CG1500,CG1500,CT3745,wr)

fw biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of a polarized epithelium GO:0001738 93 0.938
establishment of planar polarity GO:0001736 87 0.887
developmental pigmentation GO:0048066 68 0.823
pigmentation GO:0043473 75 0.729
eye pigmentation GO:0048069 43 0.676
establishment of tissue polarity GO:0007164 87 0.621
epidermis development GO:0008544 65 0.521
cuticle development GO:0042335 86 0.521
regulation of multicellular organismal development GO:2000026 414 0.508
actin cytoskeleton organization GO:0030036 206 0.461
developmental maturation GO:0021700 172 0.450
epidermal cell differentiation GO:0009913 51 0.431
pigment biosynthetic process GO:0046148 36 0.420
ocellus pigment metabolic process GO:0046158 19 0.243
epithelial cell development GO:0002064 274 0.217
epithelial cell differentiation GO:0030855 322 0.206
regulation of cell differentiation GO:0045595 302 0.202
eye pigment biosynthetic process GO:0006726 32 0.168
negative regulation of response to stimulus GO:0048585 258 0.161
single organism biosynthetic process GO:0044711 206 0.161
regulation of organ morphogenesis GO:2000027 78 0.148
regulation of response to external stimulus GO:0032101 115 0.143
Mouse
cuticle pattern formation GO:0035017 27 0.141
imaginal disc derived wing hair organization GO:0035317 45 0.139
pigment metabolic process involved in pigmentation GO:0043474 33 0.136
hematopoietic or lymphoid organ development GO:0048534 57 0.133
ommochrome metabolic process GO:0046152 19 0.125
appendage development GO:0048736 401 0.123
secondary metabolite biosynthetic process GO:0044550 24 0.117
regionalization GO:0003002 416 0.114
tissue morphogenesis GO:0048729 297 0.107
response to wounding GO:0009611 94 0.107
Mouse
antennal morphogenesis GO:0048800 14 0.105
antennal development GO:0007469 25 0.101
positive regulation of cell death GO:0010942 69 0.101
hemopoiesis GO:0030097 46 0.096
hair cell differentiation GO:0035315 47 0.096
regulation of neuron projection development GO:0010975 69 0.091
growth GO:0040007 359 0.086
eye pigment metabolic process GO:0042441 33 0.085
columnar cuboidal epithelial cell development GO:0002066 249 0.085
regulation of cell morphogenesis GO:0022604 163 0.081
establishment or maintenance of cell polarity GO:0007163 167 0.080
regulation of molecular function GO:0065009 217 0.079
chaeta development GO:0022416 97 0.076
vesicle mediated transport GO:0016192 381 0.074
imaginal disc derived wing morphogenesis GO:0007476 337 0.071
cellular component assembly involved in morphogenesis GO:0010927 151 0.071
actin filament bundle assembly GO:0051017 26 0.069
open tracheal system development GO:0007424 204 0.067
pigment metabolic process GO:0042440 84 0.063
regulation of cell death GO:0010941 173 0.063
chaeta morphogenesis GO:0008407 42 0.062
cellular amino acid metabolic process GO:0006520 61 0.058
developmental growth GO:0048589 280 0.058
organic substance transport GO:0071702 257 0.056
protein localization GO:0008104 284 0.056
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.056
neural retina development GO:0003407 4 0.056
catabolic process GO:0009056 409 0.055
embryonic development via the syncytial blastoderm GO:0001700 148 0.055
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.055
kidney morphogenesis GO:0060993 3 0.055
establishment of localization in cell GO:0051649 402 0.055
death GO:0016265 284 0.054
regulation of anatomical structure morphogenesis GO:0022603 242 0.053
anterior posterior pattern specification GO:0009952 136 0.053
immune system process GO:0002376 347 0.051
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.050
regulation of programmed cell death GO:0043067 152 0.050
appendage segmentation GO:0035285 26 0.048
morphogenesis of an epithelium GO:0002009 276 0.047
developmental growth involved in morphogenesis GO:0060560 65 0.047
ommochrome biosynthetic process GO:0006727 19 0.047
organonitrogen compound metabolic process GO:1901564 318 0.046
wing disc morphogenesis GO:0007472 344 0.046
positive regulation of retinal cell programmed cell death GO:0046670 9 0.046
morphogenesis of embryonic epithelium GO:0016331 94 0.046
single organism intracellular transport GO:1902582 207 0.046
protein modification process GO:0036211 438 0.044
imaginal disc derived appendage development GO:0048737 399 0.044
regulation of establishment of planar polarity GO:0090175 22 0.043
regulation of phosphatase activity GO:0010921 3 0.043
cellular macromolecule localization GO:0070727 220 0.042
wound healing GO:0042060 75 0.041
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.040
nephron tubule formation GO:0072079 3 0.040
positive regulation of cell differentiation GO:0045597 64 0.040
imaginal disc derived appendage morphogenesis GO:0035114 395 0.040
cell death GO:0008219 279 0.040
synaptic transmission GO:0007268 288 0.039
regulation of response to stress GO:0080134 200 0.039
Mouse
spiracle morphogenesis open tracheal system GO:0035277 22 0.039
regulation of endopeptidase activity GO:0052548 36 0.039
chemotaxis GO:0006935 249 0.038
eye development GO:0001654 323 0.038
cellular response to chemical stimulus GO:0070887 199 0.038
positive regulation of developmental process GO:0051094 143 0.038
endocytosis GO:0006897 310 0.038
protein transport GO:0015031 155 0.037
regulation of cellular localization GO:0060341 136 0.037
eye antennal disc development GO:0035214 60 0.037
regulation of localization GO:0032879 275 0.037
actin filament bundle organization GO:0061572 28 0.037
regulation of anatomical structure size GO:0090066 163 0.037
kidney development GO:0001822 3 0.036
leg disc morphogenesis GO:0007478 80 0.036
post embryonic appendage morphogenesis GO:0035120 385 0.035
regulation of peptidase activity GO:0052547 39 0.035
negative regulation of signal transduction GO:0009968 206 0.034
sex differentiation GO:0007548 81 0.033
segmentation GO:0035282 207 0.031
establishment of ommatidial planar polarity GO:0042067 49 0.031
dorsal appendage formation GO:0046843 47 0.030
actin filament organization GO:0007015 126 0.029
protein complex assembly GO:0006461 200 0.029
genital disc development GO:0035215 44 0.029
ovarian follicle cell development GO:0030707 248 0.029
regulation of cellular component biogenesis GO:0044087 201 0.028
positive regulation of cell motility GO:2000147 3 0.028
embryonic epithelial tube formation GO:0001838 6 0.028
reproductive system development GO:0061458 74 0.028
nephron development GO:0072006 3 0.028
intracellular signal transduction GO:0035556 300 0.027
single organism cell adhesion GO:0098602 47 0.027
embryonic pattern specification GO:0009880 174 0.027
organic acid metabolic process GO:0006082 103 0.027
negative regulation of organelle organization GO:0010639 56 0.027
establishment of body hair or bristle planar orientation GO:0048104 6 0.027
nephron tubule development GO:0072080 3 0.027
compound eye morphogenesis GO:0001745 249 0.026
appendage morphogenesis GO:0035107 397 0.026
tube formation GO:0035148 21 0.026
embryo development ending in birth or egg hatching GO:0009792 152 0.026
organelle assembly GO:0070925 198 0.026
response to organic substance GO:0010033 284 0.025
positive regulation of signaling GO:0023056 243 0.025
amine metabolic process GO:0009308 12 0.025
negative regulation of cell communication GO:0010648 223 0.025
eye morphogenesis GO:0048592 260 0.025
leg disc development GO:0035218 92 0.025
notch receptor processing GO:0007220 13 0.025
carboxylic acid metabolic process GO:0019752 92 0.024
ocellus pigmentation GO:0033060 19 0.024
malpighian tubule bud morphogenesis GO:0061332 3 0.024
body morphogenesis GO:0010171 2 0.024
negative regulation of signaling GO:0023057 219 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.023
positive regulation of cell communication GO:0010647 250 0.023
eye photoreceptor cell differentiation GO:0001754 145 0.023
eye photoreceptor cell development GO:0042462 81 0.023
positive regulation of cell migration GO:0030335 2 0.022
kidney epithelium development GO:0072073 3 0.021
small molecule metabolic process GO:0044281 305 0.021
nephron tubule morphogenesis GO:0072078 3 0.021
cellular response to organic substance GO:0071310 132 0.021
protein localization to organelle GO:0033365 82 0.021
embryonic hemopoiesis GO:0035162 26 0.021
organic substance catabolic process GO:1901575 308 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
lipid metabolic process GO:0006629 121 0.020
cell proliferation GO:0008283 299 0.020
response to alcohol GO:0097305 95 0.020
axon guidance GO:0007411 233 0.020
embryonic hindgut morphogenesis GO:0048619 48 0.019
actin filament based process GO:0030029 220 0.019
cellular protein localization GO:0034613 160 0.019
synapse organization GO:0050808 196 0.019
morphogenesis of a branching structure GO:0001763 45 0.019
extracellular structure organization GO:0043062 46 0.019
respiratory system development GO:0060541 213 0.019
wnt signaling pathway GO:0016055 98 0.018
imaginal disc derived leg segmentation GO:0036011 26 0.018
hindgut morphogenesis GO:0007442 58 0.018
regulation of hydrolase activity GO:0051336 97 0.018
molting cycle GO:0042303 56 0.018
ocellus pigment biosynthetic process GO:0008055 19 0.017
nephron epithelium morphogenesis GO:0072088 3 0.017
cellular modified amino acid metabolic process GO:0006575 45 0.017
nephron morphogenesis GO:0072028 3 0.017
non sensory hair organization GO:0035316 47 0.016
camera type eye photoreceptor cell differentiation GO:0060219 2 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
photoreceptor cell development GO:0042461 96 0.016
larval development GO:0002164 104 0.016
biological adhesion GO:0022610 138 0.016
membrane organization GO:0061024 112 0.016
apoptotic process GO:0006915 159 0.016
regulation of proteolysis GO:0030162 87 0.016
malpighian tubule development GO:0072002 64 0.016
cellular response to extracellular stimulus GO:0031668 64 0.016
epithelial tube morphogenesis GO:0060562 88 0.015
female sex differentiation GO:0046660 20 0.015
imaginal disc derived leg morphogenesis GO:0007480 80 0.015
cellular protein complex assembly GO:0043623 71 0.015
negative regulation of dna endoreduplication GO:0032876 2 0.015
neuron death GO:0070997 27 0.015
regulation of cell development GO:0060284 215 0.015
developmental programmed cell death GO:0010623 138 0.015
positive regulation of molecular function GO:0044093 136 0.014
establishment of protein localization GO:0045184 163 0.014
digestive system development GO:0055123 149 0.014
regulation of embryonic development GO:0045995 68 0.014
branching morphogenesis of an epithelial tube GO:0048754 45 0.014
cellular response to external stimulus GO:0071496 66 0.014
intracellular transport GO:0046907 228 0.014
positive regulation of immune system process GO:0002684 68 0.014
Mouse
regulation of rac gtpase activity GO:0032314 1 0.014
wing and notum subfield formation GO:0035309 13 0.014
learning or memory GO:0007611 141 0.014
reproductive structure development GO:0048608 74 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
proteolysis GO:0006508 192 0.014
response to other organism GO:0051707 293 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
single organism membrane organization GO:0044802 93 0.013
morphogenesis of a branching epithelium GO:0061138 45 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
negative regulation of gene expression GO:0010629 387 0.013
programmed cell death GO:0012501 257 0.013
positive regulation of signal transduction GO:0009967 223 0.013
ras protein signal transduction GO:0007265 88 0.013
cellular protein modification process GO:0006464 438 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
cell maturation GO:0048469 144 0.013
eye antennal disc morphogenesis GO:0007455 34 0.013
synapse assembly GO:0007416 143 0.012
renal tubule morphogenesis GO:0061333 44 0.012
positive regulation of response to external stimulus GO:0032103 44 0.012
purine containing compound metabolic process GO:0072521 155 0.012
striated muscle cell development GO:0055002 50 0.012
nephron epithelium development GO:0072009 3 0.012
cell fate specification GO:0001708 71 0.012
macromolecular complex assembly GO:0065003 256 0.012
positive regulation of protein import into nucleus translocation GO:0033160 2 0.012
tube development GO:0035295 244 0.012
secretion GO:0046903 109 0.012
response to lipopolysaccharide GO:0032496 4 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
protein complex biogenesis GO:0070271 201 0.012
protein processing GO:0016485 68 0.012
Mouse
regulation of protein metabolic process GO:0051246 256 0.012
Mouse
regulation of developmental growth GO:0048638 174 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
regulation of growth GO:0040008 233 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
regulation of catalytic activity GO:0050790 185 0.012
positive regulation of mapk cascade GO:0043410 63 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
equator specification GO:0045317 4 0.011
regulation of neuron death GO:1901214 26 0.011
renal tubule development GO:0061326 64 0.011
mushroom body development GO:0016319 70 0.011
skin development GO:0043588 65 0.011
cellular catabolic process GO:0044248 372 0.011
cognition GO:0050890 141 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
taxis GO:0042330 304 0.011
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.011
formation of anatomical boundary GO:0048859 37 0.011
ribose phosphate metabolic process GO:0019693 145 0.010
synaptic growth at neuromuscular junction GO:0051124 119 0.010
cytoplasmic transport GO:0016482 130 0.010
male sex differentiation GO:0046661 25 0.010
filopodium assembly GO:0046847 33 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
response to growth factor GO:0070848 31 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
organophosphate metabolic process GO:0019637 195 0.010

fw disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
disease of cellular proliferation DOID:14566 0 0.016
nervous system disease DOID:863 0 0.012
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.010