Drosophila melanogaster

49 known processes

unc (Dmel_CG1501)

uncoordinated

(Aliases: l(1)19Ef,CG1501,Dmel\CG1501,W5,l(1)6-3-212,3,UNC,5,4,lLV7)

unc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of mechanical stimulus GO:0050954 72 0.997
sensory perception of sound GO:0007605 56 0.993
cilium organization GO:0044782 41 0.988
cilium assembly GO:0042384 38 0.974
cilium morphogenesis GO:0060271 39 0.900
axoneme assembly GO:0035082 18 0.887
sensory perception GO:0007600 196 0.868
cell projection assembly GO:0030031 94 0.778
cellular component assembly involved in morphogenesis GO:0010927 151 0.639
spermatid differentiation GO:0048515 114 0.503
organelle assembly GO:0070925 198 0.380
single organism behavior GO:0044708 391 0.368
regulation of anatomical structure morphogenesis GO:0022603 242 0.341
neurological system process GO:0050877 358 0.315
epithelial cell differentiation GO:0030855 322 0.312
microtubule based movement GO:0007018 51 0.310
cell motility GO:0048870 251 0.299
sperm axoneme assembly GO:0007288 13 0.286
nonmotile primary cilium assembly GO:0035058 8 0.259
microtubule bundle formation GO:0001578 27 0.234
localization of cell GO:0051674 257 0.215
regulation of cell development GO:0060284 215 0.181
kidney development GO:0001822 3 0.171
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.151
regionalization GO:0003002 416 0.138
negative regulation of rna biosynthetic process GO:1902679 240 0.133
synaptic transmission GO:0007268 288 0.125
tube development GO:0035295 244 0.124
spermatid development GO:0007286 98 0.115
male courtship behavior veined wing generated song production GO:0045433 20 0.112
eye development GO:0001654 323 0.104
adult locomotory behavior GO:0008344 76 0.104
embryonic morphogenesis GO:0048598 206 0.097
eye morphogenesis GO:0048592 260 0.092
embryonic heart tube development GO:0035050 22 0.091
tissue morphogenesis GO:0048729 297 0.089
cellular amide metabolic process GO:0043603 80 0.087
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.086
regulation of cell differentiation GO:0045595 302 0.085
ras protein signal transduction GO:0007265 88 0.083
regulation of cell projection organization GO:0031344 92 0.082
inter male aggressive behavior GO:0002121 60 0.082
detection of external stimulus GO:0009581 66 0.073
dendrite morphogenesis GO:0048813 199 0.068
organonitrogen compound metabolic process GO:1901564 318 0.066
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.064
multi organism behavior GO:0051705 175 0.064
spermatogenesis GO:0007283 200 0.059
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.059
dorsal ventral pattern formation GO:0009953 133 0.056
regulation of embryonic development GO:0045995 68 0.054
response to nutrient levels GO:0031667 114 0.053
regulation of programmed cell death GO:0043067 152 0.053
negative regulation of cellular biosynthetic process GO:0031327 277 0.052
response to abiotic stimulus GO:0009628 341 0.051
locomotory behavior GO:0007626 176 0.051
behavioral response to pain GO:0048266 3 0.050
sperm motility GO:0030317 12 0.048
cell migration GO:0016477 238 0.048
regulation of neurogenesis GO:0050767 158 0.047
male gamete generation GO:0048232 201 0.047
sensory perception of salty taste GO:0050914 3 0.047
compound eye development GO:0048749 307 0.046
positive regulation of response to stimulus GO:0048584 323 0.045
microtubule based transport GO:0010970 42 0.045
regulation of epithelial cell proliferation GO:0050678 4 0.044
phagocytosis GO:0006909 215 0.043
morphogenesis of an epithelium GO:0002009 276 0.042
startle response GO:0001964 16 0.041
negative regulation of biosynthetic process GO:0009890 277 0.041
regulation of transport GO:0051049 181 0.041
regulation of organ morphogenesis GO:2000027 78 0.041
cell division GO:0051301 248 0.041
intracellular signal transduction GO:0035556 300 0.040
glycosyl compound metabolic process GO:1901657 127 0.040
enzyme linked receptor protein signaling pathway GO:0007167 179 0.040
sensory organ morphogenesis GO:0090596 260 0.040
sperm individualization GO:0007291 48 0.040
vesicle mediated transport GO:0016192 381 0.039
regulation of multicellular organismal development GO:2000026 414 0.039
organic acid metabolic process GO:0006082 103 0.039
wound healing GO:0042060 75 0.039
positive regulation of macromolecule metabolic process GO:0010604 405 0.039
digestive system development GO:0055123 149 0.038
regulation of response to external stimulus GO:0032101 115 0.038
antennal morphogenesis GO:0048800 14 0.037
open tracheal system development GO:0007424 204 0.036
establishment of localization in cell GO:0051649 402 0.036
cardiovascular system development GO:0072358 82 0.036
retina development in camera type eye GO:0060041 4 0.036
negative regulation of cellular metabolic process GO:0031324 382 0.035
regulation of multi organism process GO:0043900 131 0.035
cytoskeleton dependent intracellular transport GO:0030705 44 0.034
heart morphogenesis GO:0003007 32 0.034
cell death GO:0008219 279 0.034
segmentation GO:0035282 207 0.034
programmed cell death GO:0012501 257 0.033
phosphorylation GO:0016310 294 0.033
chaeta morphogenesis GO:0008407 42 0.033
negative regulation of gene expression GO:0010629 387 0.033
respiratory system development GO:0060541 213 0.033
macromolecule catabolic process GO:0009057 161 0.031
limb morphogenesis GO:0035108 1 0.031
apical constriction GO:0003383 18 0.031
immune effector process GO:0002252 98 0.031
carboxylic acid metabolic process GO:0019752 92 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.030
telencephalon development GO:0021537 2 0.030
response to oxygen containing compound GO:1901700 200 0.030
intracellular transport GO:0046907 228 0.030
negative regulation of cell differentiation GO:0045596 143 0.030
oxoacid metabolic process GO:0043436 103 0.030
hair cell differentiation GO:0035315 47 0.030
negative regulation of rna metabolic process GO:0051253 251 0.030
small gtpase mediated signal transduction GO:0007264 88 0.029
ion transmembrane transport GO:0034220 122 0.029
convergent extension GO:0060026 2 0.029
negative regulation of nucleic acid templated transcription GO:1903507 240 0.028
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.028
organic substance catabolic process GO:1901575 308 0.028
regulation of neuron differentiation GO:0045664 103 0.028
cellular amino acid metabolic process GO:0006520 61 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
negative regulation of programmed cell death GO:0043069 72 0.027
positive regulation of rna biosynthetic process GO:1902680 266 0.027
developmental programmed cell death GO:0010623 138 0.027
cellular protein modification process GO:0006464 438 0.027
purine nucleoside triphosphate metabolic process GO:0009144 119 0.027
eye antennal disc morphogenesis GO:0007455 34 0.026
epithelial tube morphogenesis GO:0060562 88 0.026
protein maturation GO:0051604 71 0.025
dendrite development GO:0016358 204 0.025
neuron recognition GO:0008038 101 0.025
renal system development GO:0072001 72 0.024
positive regulation of signaling GO:0023056 243 0.024
blastoderm segmentation GO:0007350 159 0.024
nucleus organization GO:0006997 45 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.024
regulation of nervous system development GO:0051960 248 0.024
regulation of epidermal cell differentiation GO:0045604 3 0.024
peptide metabolic process GO:0006518 80 0.024
digestive tract development GO:0048565 149 0.023
digestive tract morphogenesis GO:0048546 127 0.023
centriole assembly GO:0098534 24 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.023
small molecule metabolic process GO:0044281 305 0.023
catabolic process GO:0009056 409 0.023
tube morphogenesis GO:0035239 191 0.023
circulatory system development GO:0072359 82 0.023
adult behavior GO:0030534 137 0.023
regulation of response to stress GO:0080134 200 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
axon development GO:0061564 297 0.023
neuron neuron synaptic transmission GO:0007270 14 0.022
drinking behavior GO:0042756 2 0.022
epiboly involved in wound healing GO:0090505 2 0.022
spinal cord development GO:0021510 1 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
chemotaxis GO:0006935 249 0.022
regulation of apoptotic process GO:0042981 130 0.022
lateral inhibition GO:0046331 206 0.022
metal ion transport GO:0030001 74 0.021
death GO:0016265 284 0.021
detection of stimulus involved in sensory perception GO:0050906 92 0.021
endocytosis GO:0006897 310 0.021
detection of stimulus GO:0051606 156 0.021
imaginal disc derived wing hair organization GO:0035317 45 0.021
positive regulation of response to external stimulus GO:0032103 44 0.021
epidermis development GO:0008544 65 0.021
larval locomotory behavior GO:0008345 27 0.021
response to external biotic stimulus GO:0043207 293 0.021
cognition GO:0050890 141 0.021
embryonic organ development GO:0048568 50 0.020
regulation of cell cycle GO:0051726 291 0.020
smoothened signaling pathway GO:0007224 49 0.020
cell proliferation GO:0008283 299 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
imaginal disc derived leg morphogenesis GO:0007480 80 0.020
cellular catabolic process GO:0044248 372 0.020
biological adhesion GO:0022610 138 0.020
axonogenesis GO:0007409 290 0.020
regulation of immune response GO:0050776 118 0.020
regulation of cell morphogenesis GO:0022604 163 0.020
response to biotic stimulus GO:0009607 294 0.020
regulation of protein metabolic process GO:0051246 256 0.020
salivary gland morphogenesis GO:0007435 145 0.020
cell recognition GO:0008037 102 0.020
cytokinesis GO:0000910 90 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
protein modification process GO:0036211 438 0.019
organelle fusion GO:0048284 46 0.019
limb development GO:0060173 1 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
actin filament based process GO:0030029 220 0.019
response to lipopolysaccharide GO:0032496 4 0.019
apoptotic process GO:0006915 159 0.019
heart development GO:0007507 82 0.019
regulation of intracellular signal transduction GO:1902531 236 0.018
determination of left right symmetry GO:0007368 9 0.018
negative regulation of developmental process GO:0051093 201 0.018
appendage development GO:0048736 401 0.018
urogenital system development GO:0001655 72 0.018
neural retina development GO:0003407 4 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
regulation of cell death GO:0010941 173 0.018
intraciliary transport GO:0042073 8 0.018
regulation of cell cycle process GO:0010564 181 0.018
developmental maturation GO:0021700 172 0.018
response to pain GO:0048265 3 0.018
negative regulation of transcription dna templated GO:0045892 237 0.018
purine nucleoside monophosphate metabolic process GO:0009126 50 0.018
actin filament based movement GO:0030048 26 0.018
nitrogen compound transport GO:0071705 85 0.017
tissue migration GO:0090130 155 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
negative regulation of epithelial cell proliferation GO:0050680 4 0.017
embryonic pattern specification GO:0009880 174 0.017
larval behavior GO:0030537 42 0.017
aggressive behavior GO:0002118 63 0.017
wing disc morphogenesis GO:0007472 344 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
negative regulation of cell death GO:0060548 81 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
epithelial cell migration GO:0010631 148 0.017
actin mediated cell contraction GO:0070252 21 0.017
single organism intracellular transport GO:1902582 207 0.017
specification of symmetry GO:0009799 13 0.016
cellular macromolecule localization GO:0070727 220 0.016
regulation of cellular amide metabolic process GO:0034248 39 0.016
cytolysis GO:0019835 1 0.016
positive regulation of cell communication GO:0010647 250 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.016
regulation of response to nutrient levels GO:0032107 18 0.016
protein processing GO:0016485 68 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
single organism cell adhesion GO:0098602 47 0.016
positive regulation of gene expression GO:0010628 290 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regulation of localization GO:0032879 275 0.016
epithelium migration GO:0090132 148 0.016
regulation of ras protein signal transduction GO:0046578 93 0.015
leg disc development GO:0035218 92 0.015
muscle tissue development GO:0060537 30 0.015
antimicrobial peptide biosynthetic process GO:0002777 38 0.015
convergent extension involved in gastrulation GO:0060027 2 0.015
appendage morphogenesis GO:0035107 397 0.015
single organism catabolic process GO:0044712 228 0.015
centriole replication GO:0007099 24 0.015
spinal cord dorsal ventral patterning GO:0021513 1 0.015
gastrulation GO:0007369 70 0.015
eye antennal disc development GO:0035214 60 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
fluid transport GO:0042044 19 0.015
neuromuscular process GO:0050905 21 0.015
regulation of circadian rhythm GO:0042752 49 0.015
skin development GO:0043588 65 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
cellular response to radiation GO:0071478 52 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
regulation of humoral immune response GO:0002920 51 0.014
sensory perception of touch GO:0050975 11 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
compound eye retinal cell programmed cell death GO:0046667 23 0.014
positive regulation of multi organism process GO:0043902 40 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
anatomical structure homeostasis GO:0060249 97 0.014
anterior posterior pattern specification GO:0009952 136 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
antimicrobial humoral response GO:0019730 99 0.014
multi multicellular organism process GO:0044706 123 0.014
negative regulation of sequestering of calcium ion GO:0051283 2 0.014
ion transport GO:0006811 145 0.014
actin filament bundle assembly GO:0051017 26 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
regulation of mitotic cell cycle GO:0007346 190 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
chaeta development GO:0022416 97 0.013
positive regulation of antimicrobial humoral response GO:0002760 28 0.013
notch signaling pathway GO:0007219 120 0.013
positive regulation of signal transduction GO:0009967 223 0.013
imaginal disc pattern formation GO:0007447 91 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
salivary gland development GO:0007431 162 0.013
innate immune response GO:0045087 144 0.013
lipid metabolic process GO:0006629 121 0.013
regulation of retinal cell programmed cell death GO:0046668 18 0.013
cellular response to abiotic stimulus GO:0071214 58 0.013
learning GO:0007612 75 0.013
cellular ion homeostasis GO:0006873 39 0.013
neurotransmitter metabolic process GO:0042133 2 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
photoreceptor cell development GO:0042461 96 0.013
epithelial cell development GO:0002064 274 0.013
gland morphogenesis GO:0022612 145 0.013
regulation of production of molecular mediator of immune response GO:0002700 44 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
ribose phosphate metabolic process GO:0019693 145 0.012
histolysis GO:0007559 102 0.012
regulation of cellular localization GO:0060341 136 0.012
muscle tissue morphogenesis GO:0060415 2 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
regulation of smoothened signaling pathway GO:0008589 28 0.012
regulation of nucleotide catabolic process GO:0030811 48 0.012
positive regulation of response to biotic stimulus GO:0002833 31 0.012
regulation of immune system process GO:0002682 176 0.012
male courtship behavior veined wing extension GO:0048065 22 0.012
electron transport chain GO:0022900 14 0.012
hindbrain development GO:0030902 2 0.012
antimicrobial peptide production GO:0002775 46 0.012
regulation of catalytic activity GO:0050790 185 0.012
organophosphate metabolic process GO:0019637 195 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
amine metabolic process GO:0009308 12 0.012
response to glucose GO:0009749 2 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
intraspecies interaction between organisms GO:0051703 4 0.012
chemosensory behavior GO:0007635 106 0.012
determination of bilateral symmetry GO:0009855 13 0.012
peripheral nervous system development GO:0007422 52 0.012
negative regulation of signal transduction GO:0009968 206 0.012
aromatic compound catabolic process GO:0019439 166 0.012
forebrain development GO:0030900 2 0.012
regulation of cell proliferation GO:0042127 163 0.012
cellular response to water stimulus GO:0071462 2 0.012
response to radiation GO:0009314 155 0.011
organ formation GO:0048645 39 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
cranial nerve development GO:0021545 1 0.011
protein phosphorylation GO:0006468 169 0.011
retinal cell programmed cell death GO:0046666 25 0.011
nucleoside catabolic process GO:0009164 112 0.011
epithelial cell morphogenesis GO:0003382 25 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
response to extracellular stimulus GO:0009991 116 0.011
muscle structure development GO:0061061 224 0.011
organic substance transport GO:0071702 257 0.011
cardioblast differentiation GO:0010002 20 0.011
amino acid transport GO:0006865 12 0.011
spinal cord patterning GO:0021511 1 0.011
actin cytoskeleton organization GO:0030036 206 0.011
purine containing compound metabolic process GO:0072521 155 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
retina morphogenesis in camera type eye GO:0060042 2 0.010
positive regulation of cell differentiation GO:0045597 64 0.010
cellular ketone metabolic process GO:0042180 24 0.010
eye photoreceptor cell development GO:0042462 81 0.010
gland development GO:0048732 191 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
central nervous system development GO:0007417 201 0.010
learning or memory GO:0007611 141 0.010
organic hydroxy compound metabolic process GO:1901615 83 0.010
camera type eye development GO:0043010 4 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
carbohydrate metabolic process GO:0005975 82 0.010
cell fate specification GO:0001708 71 0.010
production of molecular mediator of immune response GO:0002440 46 0.010

unc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.127
urinary system disease DOID:18 0 0.127
respiratory system disease DOID:1579 0 0.036
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.020
auditory system disease DOID:2742 0 0.020
sensory system disease DOID:0050155 0 0.020
nervous system disease DOID:863 0 0.020
lower respiratory tract disease DOID:0050161 0 0.019
bronchial disease DOID:1176 0 0.019
nonsyndromic deafness DOID:0050563 0 0.014
bronchiectasis DOID:9563 0 0.013
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.012
renal tubular transport disease DOID:447 0 0.011
kidney disease DOID:557 0 0.011