Drosophila melanogaster

27 known processes

5-HT1B (Dmel_CG15113)

Serotonin receptor 1B

(Aliases: DRO2B,5-HT[1B]Dro,CG15113,5HT1B,Dm5HTdro2B,5-HT1BDro,5-HT-dro2B,5HT-dro2B,5-HT[[1BDro]],Dmel\CG15113,5htdro2b,d5-HT1B,5HT-dro[[2B]],5HT-R2B,5-HT[[dro2B]])

5-HT1B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cyclic nucleotide biosynthetic process GO:0009190 25 0.354
regulation of camp biosynthetic process GO:0030817 12 0.343
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.271
purine containing compound biosynthetic process GO:0072522 30 0.224
negative regulation of cellular biosynthetic process GO:0031327 277 0.210
cyclic purine nucleotide metabolic process GO:0052652 25 0.208
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.197
ribose phosphate biosynthetic process GO:0046390 28 0.177
purine nucleotide metabolic process GO:0006163 146 0.167
camp metabolic process GO:0046058 19 0.163
negative regulation of cellular metabolic process GO:0031324 382 0.163
g protein coupled receptor signaling pathway GO:0007186 136 0.148
negative regulation of biosynthetic process GO:0009890 277 0.144
carbohydrate derivative biosynthetic process GO:1901137 85 0.142
nucleobase containing small molecule metabolic process GO:0055086 174 0.141
single organism behavior GO:0044708 391 0.136
Fly
establishment of localization in cell GO:0051649 402 0.128
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.125
organophosphate metabolic process GO:0019637 195 0.123
regulation of localization GO:0032879 275 0.120
regulation of phosphate metabolic process GO:0019220 210 0.120
regulation of cyclic nucleotide biosynthetic process GO:0030802 13 0.119
purine ribonucleotide biosynthetic process GO:0009152 28 0.116
cyclic nucleotide metabolic process GO:0009187 28 0.116
nucleoside phosphate biosynthetic process GO:1901293 34 0.113
nucleotide metabolic process GO:0009117 161 0.112
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.107
organonitrogen compound metabolic process GO:1901564 318 0.101
ribonucleotide metabolic process GO:0009259 145 0.101
negative regulation of cell communication GO:0010648 223 0.101
ribose phosphate metabolic process GO:0019693 145 0.100
negative regulation of signaling GO:0023057 219 0.098
purine containing compound metabolic process GO:0072521 155 0.097
regulation of catalytic activity GO:0050790 185 0.096
regulation of adenylate cyclase activity GO:0045761 12 0.093
regulation of phosphorus metabolic process GO:0051174 210 0.092
cellular protein modification process GO:0006464 438 0.088
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.088
negative regulation of rna metabolic process GO:0051253 251 0.085
organophosphate biosynthetic process GO:0090407 46 0.085
synaptic transmission GO:0007268 288 0.083
protein modification process GO:0036211 438 0.078
olfactory behavior GO:0042048 97 0.078
positive regulation of macromolecule metabolic process GO:0010604 405 0.078
camp biosynthetic process GO:0006171 17 0.077
negative regulation of gene expression GO:0010629 387 0.076
regulation of lyase activity GO:0051339 14 0.074
response to abiotic stimulus GO:0009628 341 0.073
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.073
organonitrogen compound biosynthetic process GO:1901566 117 0.072
regulation of camp metabolic process GO:0030814 12 0.070
carbohydrate derivative metabolic process GO:1901135 217 0.070
synaptic vesicle transport GO:0048489 50 0.068
regulation of nucleotide biosynthetic process GO:0030808 14 0.065
regulation of cell development GO:0060284 215 0.063
single organism biosynthetic process GO:0044711 206 0.062
ribonucleotide biosynthetic process GO:0009260 28 0.062
regulation of multicellular organismal development GO:2000026 414 0.062
regulation of molecular function GO:0065009 217 0.062
regulation of organelle organization GO:0033043 196 0.061
negative regulation of transcription dna templated GO:0045892 237 0.061
secretion GO:0046903 109 0.061
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.060
small molecule metabolic process GO:0044281 305 0.059
organelle fusion GO:0048284 46 0.059
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.058
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.058
eye morphogenesis GO:0048592 260 0.058
vesicle mediated transport GO:0016192 381 0.057
negative regulation of insulin secretion GO:0046676 1 0.057
eye development GO:0001654 323 0.056
positive regulation of rna metabolic process GO:0051254 271 0.056
regulation of transport GO:0051049 181 0.055
negative regulation of nucleic acid templated transcription GO:1903507 240 0.055
regulation of purine nucleotide metabolic process GO:1900542 62 0.055
positive regulation of phosphorus metabolic process GO:0010562 139 0.054
positive regulation of rna biosynthetic process GO:1902680 266 0.054
regulation of nucleotide metabolic process GO:0006140 62 0.054
regionalization GO:0003002 416 0.054
vesicle localization GO:0051648 55 0.054
regulation of mitotic cell cycle GO:0007346 190 0.054
negative regulation of rna biosynthetic process GO:1902679 240 0.053
regulation of cell cycle GO:0051726 291 0.053
catabolic process GO:0009056 409 0.053
tube development GO:0035295 244 0.053
membrane organization GO:0061024 112 0.052
positive regulation of nucleic acid templated transcription GO:1903508 266 0.051
regulation of cyclase activity GO:0031279 13 0.051
positive regulation of phosphate metabolic process GO:0045937 139 0.051
camera type eye development GO:0043010 4 0.050
single organism membrane organization GO:0044802 93 0.050
positive regulation of cellular biosynthetic process GO:0031328 316 0.049
transcription from rna polymerase ii promoter GO:0006366 368 0.049
purine ribonucleotide metabolic process GO:0009150 145 0.046
purine nucleotide biosynthetic process GO:0006164 29 0.046
regulation of cellular localization GO:0060341 136 0.045
cellular catabolic process GO:0044248 372 0.045
positive regulation of biosynthetic process GO:0009891 316 0.045
adult behavior GO:0030534 137 0.045
negative regulation of peptide secretion GO:0002792 1 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.045
intracellular signal transduction GO:0035556 300 0.044
nucleoside phosphate metabolic process GO:0006753 162 0.044
regulation of intracellular signal transduction GO:1902531 236 0.044
synaptic vesicle exocytosis GO:0016079 16 0.044
defense response GO:0006952 300 0.044
organelle fission GO:0048285 340 0.043
nucleotide biosynthetic process GO:0009165 34 0.043
phosphorylation GO:0016310 294 0.043
axonogenesis GO:0007409 290 0.042
positive regulation of signal transduction GO:0009967 223 0.042
vesicle organization GO:0016050 44 0.042
regulation of cell differentiation GO:0045595 302 0.042
appendage morphogenesis GO:0035107 397 0.042
lateral inhibition GO:0046331 206 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.042
establishment of vesicle localization GO:0051650 51 0.042
chemosensory behavior GO:0007635 106 0.041
neurotransmitter secretion GO:0007269 35 0.040
regulation of synaptic transmission GO:0050804 69 0.040
compound eye morphogenesis GO:0001745 249 0.039
regulation of protein metabolic process GO:0051246 256 0.039
regulation of cellular protein metabolic process GO:0032268 243 0.039
single organism catabolic process GO:0044712 228 0.038
neurotransmitter transport GO:0006836 37 0.038
establishment of organelle localization GO:0051656 122 0.038
establishment of synaptic vesicle localization GO:0097480 50 0.038
positive regulation of developmental process GO:0051094 143 0.038
positive regulation of catalytic activity GO:0043085 118 0.038
developmental maturation GO:0021700 172 0.038
tube morphogenesis GO:0035239 191 0.037
locomotory behavior GO:0007626 176 0.037
regulation of cell proliferation GO:0042127 163 0.037
body morphogenesis GO:0010171 2 0.037
ras protein signal transduction GO:0007265 88 0.037
chemotaxis GO:0006935 249 0.037
regulation of nervous system development GO:0051960 248 0.037
regulation of gene expression epigenetic GO:0040029 128 0.036
cell death GO:0008219 279 0.036
positive regulation of molecular function GO:0044093 136 0.036
taxis GO:0042330 304 0.035
organic substance catabolic process GO:1901575 308 0.035
regulation of catabolic process GO:0009894 170 0.035
positive regulation of nucleotide metabolic process GO:0045981 55 0.034
mitotic nuclear division GO:0007067 213 0.034
regulation of vesicle mediated transport GO:0060627 59 0.034
axon development GO:0061564 297 0.034
axon guidance GO:0007411 233 0.034
regulation of cell cycle process GO:0010564 181 0.034
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
regulation of cellular ketone metabolic process GO:0010565 3 0.033
protein localization GO:0008104 284 0.033
regulation of response to stress GO:0080134 200 0.033
organelle localization GO:0051640 148 0.033
endocytosis GO:0006897 310 0.033
positive regulation of transcription dna templated GO:0045893 266 0.033
compound eye development GO:0048749 307 0.033
appendage development GO:0048736 401 0.032
negative regulation of phosphate metabolic process GO:0045936 45 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
regulation of neurogenesis GO:0050767 158 0.032
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.031
dna metabolic process GO:0006259 227 0.031
notch signaling pathway GO:0007219 120 0.031
positive regulation of signaling GO:0023056 243 0.031
imaginal disc derived appendage morphogenesis GO:0035114 395 0.030
negative regulation of phosphorus metabolic process GO:0010563 45 0.030
response to other organism GO:0051707 293 0.030
organic cyclic compound catabolic process GO:1901361 168 0.029
positive regulation of gene expression GO:0010628 290 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
regulation of anatomical structure morphogenesis GO:0022603 242 0.029
cell migration GO:0016477 238 0.029
connective tissue development GO:0061448 3 0.029
homeostatic process GO:0042592 199 0.029
tissue morphogenesis GO:0048729 297 0.029
morphogenesis of an epithelium GO:0002009 276 0.029
positive regulation of protein metabolic process GO:0051247 128 0.029
imaginal disc derived appendage development GO:0048737 399 0.029
regulation of secretion GO:0051046 44 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
exocytosis GO:0006887 28 0.028
defense response to bacterium GO:0042742 178 0.028
programmed cell death GO:0012501 257 0.028
kidney development GO:0001822 3 0.028
regulation of circadian rhythm GO:0042752 49 0.028
negative regulation of multicellular organismal process GO:0051241 142 0.028
forebrain development GO:0030900 2 0.028
kidney epithelium development GO:0072073 3 0.028
regulation of cellular component biogenesis GO:0044087 201 0.028
telencephalon development GO:0021537 2 0.027
nucleobase containing compound catabolic process GO:0034655 165 0.027
ribonucleoside triphosphate metabolic process GO:0009199 119 0.027
cellular macromolecule localization GO:0070727 220 0.027
cell adhesion GO:0007155 136 0.027
neuroblast proliferation GO:0007405 74 0.027
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 3 0.027
wing disc morphogenesis GO:0007472 344 0.027
response to bacterium GO:0009617 198 0.027
glycosyl compound metabolic process GO:1901657 127 0.027
oocyte differentiation GO:0009994 145 0.027
regulation of phosphorylation GO:0042325 147 0.027
mapk cascade GO:0000165 107 0.027
nucleoside metabolic process GO:0009116 127 0.026
sensory organ morphogenesis GO:0090596 260 0.026
negative regulation of camp metabolic process GO:0030815 3 0.026
purine ribonucleoside metabolic process GO:0046128 127 0.026
negative regulation of cellular component organization GO:0051129 108 0.026
cell division GO:0051301 248 0.026
heterocycle catabolic process GO:0046700 166 0.026
organic substance transport GO:0071702 257 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.026
regulation of cellular catabolic process GO:0031329 157 0.026
purine nucleoside metabolic process GO:0042278 127 0.026
negative regulation of signal transduction GO:0009968 206 0.026
cell maturation GO:0048469 144 0.026
nuclear division GO:0000280 332 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.026
purine ribonucleoside catabolic process GO:0046130 112 0.026
cytoplasmic transport GO:0016482 130 0.026
positive regulation of cell communication GO:0010647 250 0.025
protein phosphorylation GO:0006468 169 0.025
small gtpase mediated signal transduction GO:0007264 88 0.025
phagocytosis GO:0006909 215 0.025
endomembrane system organization GO:0010256 119 0.025
purine ribonucleotide catabolic process GO:0009154 109 0.025
gland development GO:0048732 191 0.025
aromatic compound catabolic process GO:0019439 166 0.025
neuron projection guidance GO:0097485 241 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
intracellular transport GO:0046907 228 0.024
nucleoside triphosphate catabolic process GO:0009143 108 0.024
chromatin organization GO:0006325 207 0.024
anterior posterior axis specification GO:0009948 109 0.024
nitrogen compound transport GO:0071705 85 0.024
growth GO:0040007 359 0.024
stem cell proliferation GO:0072089 88 0.024
oocyte development GO:0048599 124 0.024
regulation of cell death GO:0010941 173 0.024
cell proliferation GO:0008283 299 0.024
death GO:0016265 284 0.024
regulation of hormone levels GO:0010817 40 0.023
cellular ketone metabolic process GO:0042180 24 0.023
sleep GO:0030431 49 0.023
Fly
positive regulation of cell development GO:0010720 61 0.023
positive regulation of cell motility GO:2000147 3 0.023
negative regulation of peptide hormone secretion GO:0090278 1 0.023
nucleotide catabolic process GO:0009166 109 0.023
regulation of cell cycle phase transition GO:1901987 130 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
ribonucleoside triphosphate catabolic process GO:0009203 108 0.023
response to biotic stimulus GO:0009607 294 0.023
regulation of epithelial cell proliferation GO:0050678 4 0.023
positive regulation of cellular component organization GO:0051130 156 0.023
adult locomotory behavior GO:0008344 76 0.023
anterior posterior pattern specification GO:0009952 136 0.023
immune response GO:0006955 246 0.022
negative regulation of molecular function GO:0044092 51 0.022
anterior posterior axis specification embryo GO:0008595 103 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.022
carbohydrate derivative catabolic process GO:1901136 118 0.022
camera type eye morphogenesis GO:0048593 2 0.022
actin cytoskeleton organization GO:0030036 206 0.022
immune system process GO:0002376 347 0.022
regulation of programmed cell death GO:0043067 152 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.022
ion transmembrane transport GO:0034220 122 0.022
digestive system development GO:0055123 149 0.022
salivary gland morphogenesis GO:0007435 145 0.022
rhythmic process GO:0048511 106 0.022
cell motility GO:0048870 251 0.022
cell recognition GO:0008037 102 0.022
purine nucleoside triphosphate metabolic process GO:0009144 119 0.022
biological adhesion GO:0022610 138 0.022
regulation of behavior GO:0050795 75 0.021
Fly
negative regulation of response to stimulus GO:0048585 258 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
imaginal disc pattern formation GO:0007447 91 0.021
localization of cell GO:0051674 257 0.021
salivary gland development GO:0007431 162 0.021
response to external biotic stimulus GO:0043207 293 0.021
response to organic substance GO:0010033 284 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
protein transport GO:0015031 155 0.021
multicellular organismal reproductive behavior GO:0033057 110 0.021
Fly
dendrite development GO:0016358 204 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.021
establishment of protein localization GO:0045184 163 0.021
purine nucleotide catabolic process GO:0006195 109 0.021
regulation of secretion by cell GO:1903530 39 0.021
mrna metabolic process GO:0016071 124 0.021
positive regulation of catabolic process GO:0009896 105 0.021
segmentation GO:0035282 207 0.021
nucleoside catabolic process GO:0009164 112 0.021
cell cycle phase transition GO:0044770 140 0.020
metal ion homeostasis GO:0055065 44 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
apoptotic process GO:0006915 159 0.020
cellular protein localization GO:0034613 160 0.020
nucleoside triphosphate metabolic process GO:0009141 120 0.020
positive regulation of nervous system development GO:0051962 69 0.020
response to light stimulus GO:0009416 124 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
gland morphogenesis GO:0022612 145 0.020
nephron development GO:0072006 3 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
exocrine system development GO:0035272 162 0.020
neural precursor cell proliferation GO:0061351 75 0.020
cellular response to dna damage stimulus GO:0006974 223 0.020
embryonic pattern specification GO:0009880 174 0.020
regulation of mapk cascade GO:0043408 92 0.020
actin filament based process GO:0030029 220 0.019
regulation of small gtpase mediated signal transduction GO:0051056 93 0.019
regulation of immune system process GO:0002682 176 0.019
response to starvation GO:0042594 97 0.019
secretion by cell GO:0032940 101 0.019
chromosome organization GO:0051276 360 0.019
single organism cellular localization GO:1902580 180 0.019
response to lipopolysaccharide GO:0032496 4 0.019
axis specification GO:0009798 167 0.019
tripartite regional subdivision GO:0007351 103 0.019
negative regulation of catalytic activity GO:0043086 42 0.019
positive regulation of lyase activity GO:0051349 10 0.019
negative regulation of organelle organization GO:0010639 56 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
negative regulation of developmental process GO:0051093 201 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
epithelial tube morphogenesis GO:0060562 88 0.019
retina development in camera type eye GO:0060041 4 0.019
kidney morphogenesis GO:0060993 3 0.019
chemical homeostasis GO:0048878 92 0.019
spindle organization GO:0007051 253 0.019
limb development GO:0060173 1 0.019
regulation of apoptotic process GO:0042981 130 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
positive regulation of cell migration GO:0030335 2 0.018
positive regulation of phosphorylation GO:0042327 87 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
neurological system process GO:0050877 358 0.018
Fly
organic acid metabolic process GO:0006082 103 0.018
regulation of neurotransmitter secretion GO:0046928 14 0.018
purine containing compound catabolic process GO:0072523 112 0.018
compound eye photoreceptor cell differentiation GO:0001751 140 0.018
positive regulation of nucleoside metabolic process GO:0045979 47 0.017
regulation of cellular response to stress GO:0080135 89 0.017
muscle structure development GO:0061061 224 0.017
embryonic axis specification GO:0000578 107 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
regulation of anatomical structure size GO:0090066 163 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
macromolecular complex assembly GO:0065003 256 0.017
regulation of neurotransmitter levels GO:0001505 38 0.017
wing disc pattern formation GO:0035222 66 0.017
transmembrane transport GO:0055085 139 0.017
regulation of steroid metabolic process GO:0019218 2 0.017
positive regulation of mapk cascade GO:0043410 63 0.017
cellular homeostasis GO:0019725 80 0.017
autophagy GO:0006914 108 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
response to monosaccharide GO:0034284 4 0.017
mesenchymal cell differentiation GO:0048762 1 0.017
regulation of synapse organization GO:0050807 110 0.017
oxoacid metabolic process GO:0043436 103 0.017
larval behavior GO:0030537 42 0.017
negative regulation of cell death GO:0060548 81 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
protein targeting GO:0006605 64 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
protein complex biogenesis GO:0070271 201 0.016
regulation of protein modification process GO:0031399 112 0.016
response to temperature stimulus GO:0009266 106 0.016
dendrite morphogenesis GO:0048813 199 0.016
single organism intracellular transport GO:1902582 207 0.016
endodermal cell differentiation GO:0035987 3 0.016
blastoderm segmentation GO:0007350 159 0.016
positive regulation of cell cycle GO:0045787 43 0.016
nephron morphogenesis GO:0072028 3 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
oocyte construction GO:0007308 112 0.016
peptidyl amino acid modification GO:0018193 105 0.016
regulation of developmental growth GO:0048638 174 0.016
mitotic spindle organization GO:0007052 220 0.016
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 9 0.016
cellular metal ion homeostasis GO:0006875 31 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
mrna processing GO:0006397 104 0.015
negative regulation of purine nucleotide biosynthetic process GO:1900372 3 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
circadian rhythm GO:0007623 105 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
regulation of synapse assembly GO:0051963 94 0.015
macromolecule catabolic process GO:0009057 161 0.015
positive regulation of axonogenesis GO:0050772 2 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
nephron epithelium morphogenesis GO:0072088 3 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
organophosphate catabolic process GO:0046434 112 0.015
positive regulation of nucleotide catabolic process GO:0030813 46 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
negative regulation of cell development GO:0010721 62 0.015
head development GO:0060322 135 0.015
extrinsic apoptotic signaling pathway GO:0097191 1 0.015
spermatogenesis GO:0007283 200 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
regulation of mitosis GO:0007088 56 0.015
detection of stimulus GO:0051606 156 0.015
response to organophosphorus GO:0046683 2 0.015
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.015
regulation of cell division GO:0051302 72 0.015
synaptic growth at neuromuscular junction GO:0051124 119 0.015
regulation of stem cell proliferation GO:0072091 40 0.015
hindbrain development GO:0030902 2 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
protein complex assembly GO:0006461 200 0.014
muscle organ development GO:0007517 127 0.014
negative regulation of nucleotide biosynthetic process GO:0030809 3 0.014
response to wounding GO:0009611 94 0.014
gtp catabolic process GO:0006184 72 0.014
stress activated mapk cascade GO:0051403 52 0.014
rna processing GO:0006396 147 0.014
regulation of embryonic development GO:0045995 68 0.014
neuron fate commitment GO:0048663 50 0.014
rna localization GO:0006403 115 0.014
regulation of reproductive process GO:2000241 54 0.014
gtp metabolic process GO:0046039 72 0.014
stress activated protein kinase signaling cascade GO:0031098 55 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
renal system development GO:0072001 72 0.014
regulation of organ morphogenesis GO:2000027 78 0.014
response to radiation GO:0009314 155 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
chromatin silencing GO:0006342 76 0.014
regulation of response to external stimulus GO:0032101 115 0.014
central nervous system development GO:0007417 201 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.014
urogenital system development GO:0001655 72 0.014
nephron tubule development GO:0072080 3 0.014
detection of stimulus involved in sensory perception GO:0050906 92 0.014
negative regulation of gene expression epigenetic GO:0045814 77 0.014
mesoderm development GO:0007498 78 0.014
myotube cell development GO:0014904 3 0.013
male gamete generation GO:0048232 201 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
mating GO:0007618 120 0.013
Fly
amine metabolic process GO:0009308 12 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
circadian sleep wake cycle GO:0042745 28 0.013
Fly
regulation of circadian sleep wake cycle GO:0042749 25 0.013
Fly
neuropeptide signaling pathway GO:0007218 45 0.013
olfactory learning GO:0008355 56 0.013
cation homeostasis GO:0055080 51 0.013
response to oxygen containing compound GO:1901700 200 0.013
single organism membrane fusion GO:0044801 42 0.013
gene silencing GO:0016458 138 0.013
eye antennal disc development GO:0035214 60 0.013
regulation of hydrolase activity GO:0051336 97 0.013
proteolysis GO:0006508 192 0.013
epithelial cell differentiation GO:0030855 322 0.013
regulation of multi organism process GO:0043900 131 0.013
digestive tract development GO:0048565 149 0.013
positive regulation of organelle organization GO:0010638 65 0.013
endoderm formation GO:0001706 3 0.013
innate immune response GO:0045087 144 0.013
maternal determination of anterior posterior axis embryo GO:0008358 74 0.013
developmental programmed cell death GO:0010623 138 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
positive regulation of cyclic nucleotide metabolic process GO:0030801 9 0.013
defense response to other organism GO:0098542 225 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
cardiovascular system development GO:0072358 82 0.013
multi organism reproductive behavior GO:0044705 121 0.013
Fly
defense response to gram negative bacterium GO:0050829 94 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
regulation of neurotransmitter transport GO:0051588 14 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
positive regulation of cell differentiation GO:0045597 64 0.013
mesenchymal cell development GO:0014031 1 0.012
protein localization to nucleus GO:0034504 55 0.012
regulation of gene silencing GO:0060968 63 0.012
carbohydrate metabolic process GO:0005975 82 0.012
cell cycle checkpoint GO:0000075 95 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012

5-HT1B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
nervous system disease DOID:863 0 0.028
cardiovascular system disease DOID:1287 0 0.018
musculoskeletal system disease DOID:17 0 0.015
vascular disease DOID:178 0 0.014
hypertension DOID:10763 0 0.014
artery disease DOID:0050828 0 0.014
disease of metabolism DOID:0014667 0 0.012