Drosophila melanogaster

40 known processes

hdm (Dmel_CG15329)

hold'em

(Aliases: Dmel\CG15329,CG15329)

hdm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle process GO:1903046 132 0.489
reciprocal meiotic recombination GO:0007131 19 0.466
reciprocal dna recombination GO:0035825 19 0.303
meiosis i GO:0007127 59 0.297
dna recombination GO:0006310 32 0.290
meiotic nuclear division GO:0007126 151 0.273
meiotic cell cycle GO:0051321 171 0.233
nuclear division GO:0000280 332 0.232
organelle fission GO:0048285 340 0.191
male meiosis GO:0007140 52 0.113
dna metabolic process GO:0006259 227 0.088
meiotic chromosome segregation GO:0045132 59 0.085
cellular catabolic process GO:0044248 372 0.083
organonitrogen compound metabolic process GO:1901564 318 0.082
single organism catabolic process GO:0044712 228 0.075
response to abiotic stimulus GO:0009628 341 0.065
catabolic process GO:0009056 409 0.062
heterocycle catabolic process GO:0046700 166 0.061
nucleobase containing compound catabolic process GO:0034655 165 0.059
single organism behavior GO:0044708 391 0.055
chromosome segregation GO:0007059 157 0.049
small molecule metabolic process GO:0044281 305 0.047
regionalization GO:0003002 416 0.043
neurological system process GO:0050877 358 0.042
response to temperature stimulus GO:0009266 106 0.041
localization of cell GO:0051674 257 0.041
organic substance catabolic process GO:1901575 308 0.041
male gamete generation GO:0048232 201 0.040
cellular nitrogen compound catabolic process GO:0044270 165 0.040
macromolecular complex assembly GO:0065003 256 0.038
vesicle mediated transport GO:0016192 381 0.037
purine containing compound metabolic process GO:0072521 155 0.037
regulation of mitotic cell cycle phase transition GO:1901990 130 0.036
nucleobase containing small molecule metabolic process GO:0055086 174 0.036
endocytosis GO:0006897 310 0.035
cellular component assembly involved in morphogenesis GO:0010927 151 0.035
aromatic compound catabolic process GO:0019439 166 0.034
cellular response to dna damage stimulus GO:0006974 223 0.034
transcription from rna polymerase ii promoter GO:0006366 368 0.034
female meiotic division GO:0007143 70 0.034
axis specification GO:0009798 167 0.033
epithelial cell development GO:0002064 274 0.033
organic cyclic compound catabolic process GO:1901361 168 0.032
recombinational repair GO:0000725 13 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.031
carboxylic acid metabolic process GO:0019752 92 0.031
detection of stimulus GO:0051606 156 0.031
purine ribonucleotide metabolic process GO:0009150 145 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.030
spermatogenesis GO:0007283 200 0.030
dna repair GO:0006281 54 0.030
organophosphate metabolic process GO:0019637 195 0.030
response to nutrient levels GO:0031667 114 0.030
oxoacid metabolic process GO:0043436 103 0.030
positive regulation of gene expression GO:0010628 290 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.029
positive regulation of transcription dna templated GO:0045893 266 0.029
hormone catabolic process GO:0042447 3 0.029
sensory perception GO:0007600 196 0.029
dorsal ventral pattern formation GO:0009953 133 0.029
macromolecule catabolic process GO:0009057 161 0.029
purine nucleoside catabolic process GO:0006152 112 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
regulation of organelle organization GO:0033043 196 0.028
inter male aggressive behavior GO:0002121 60 0.028
response to organic substance GO:0010033 284 0.028
protein modification process GO:0036211 438 0.028
phagocytosis GO:0006909 215 0.028
sensory perception of smell GO:0007608 80 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
negative regulation of developmental process GO:0051093 201 0.026
cellular protein modification process GO:0006464 438 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
dorsal ventral axis specification GO:0009950 66 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
purine ribonucleoside catabolic process GO:0046130 112 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.025
anterior posterior pattern specification GO:0009952 136 0.025
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.025
purine ribonucleoside metabolic process GO:0046128 127 0.025
cell fate determination GO:0001709 91 0.025
protein maturation GO:0051604 71 0.025
proteolysis GO:0006508 192 0.024
positive regulation of rna metabolic process GO:0051254 271 0.024
sensory perception of chemical stimulus GO:0007606 116 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
developmental growth GO:0048589 280 0.024
dorsal appendage formation GO:0046843 47 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.023
epithelial cell differentiation GO:0030855 322 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
nucleoside triphosphate metabolic process GO:0009141 120 0.023
cellular macromolecular complex assembly GO:0034622 153 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
taxis GO:0042330 304 0.023
organelle assembly GO:0070925 198 0.022
protein dna complex subunit organization GO:0071824 86 0.022
nucleoside metabolic process GO:0009116 127 0.022
nucleoside catabolic process GO:0009164 112 0.022
purine containing compound catabolic process GO:0072523 112 0.022
cell cycle phase transition GO:0044770 140 0.022
response to oxygen containing compound GO:1901700 200 0.021
ribose phosphate metabolic process GO:0019693 145 0.021
response to light stimulus GO:0009416 124 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
purine nucleoside metabolic process GO:0042278 127 0.021
nucleotide metabolic process GO:0009117 161 0.021
ribonucleoside catabolic process GO:0042454 112 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
chromosome organization GO:0051276 360 0.021
developmental maturation GO:0021700 172 0.021
intracellular signal transduction GO:0035556 300 0.021
mitochondrion organization GO:0007005 65 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
glycosyl compound catabolic process GO:1901658 112 0.020
ribonucleoside metabolic process GO:0009119 127 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
xenobiotic catabolic process GO:0042178 1 0.020
regulation of cell cycle GO:0051726 291 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.020
regulation of molecular function GO:0065009 217 0.020
chaeta development GO:0022416 97 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
regulation of cell differentiation GO:0045595 302 0.020
organic acid metabolic process GO:0006082 103 0.019
compound eye development GO:0048749 307 0.019
protein complex assembly GO:0006461 200 0.019
regulation of developmental growth GO:0048638 174 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
negative regulation of gene expression GO:0010629 387 0.019
organophosphate catabolic process GO:0046434 112 0.019
cell maturation GO:0048469 144 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
phosphorylation GO:0016310 294 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
stem cell differentiation GO:0048863 117 0.018
wing disc morphogenesis GO:0007472 344 0.018
response to biotic stimulus GO:0009607 294 0.018
multi organism behavior GO:0051705 175 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
synaptic transmission GO:0007268 288 0.018
cholesterol homeostasis GO:0042632 3 0.018
positive regulation of cell communication GO:0010647 250 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
camera type eye development GO:0043010 4 0.018
body morphogenesis GO:0010171 2 0.018
cellular macromolecule localization GO:0070727 220 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.017
detection of stimulus involved in sensory perception GO:0050906 92 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
single organism intracellular transport GO:1902582 207 0.017
protein phosphorylation GO:0006468 169 0.017
eye morphogenesis GO:0048592 260 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
appendage development GO:0048736 401 0.017
double strand break repair GO:0006302 26 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
mitotic dna integrity checkpoint GO:0044774 75 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
organic substance transport GO:0071702 257 0.016
locomotory behavior GO:0007626 176 0.016
response to other organism GO:0051707 293 0.016
cell division GO:0051301 248 0.016
protein localization GO:0008104 284 0.016
cellular amine metabolic process GO:0044106 12 0.016
transmembrane transport GO:0055085 139 0.016
nucleoside triphosphate catabolic process GO:0009143 108 0.016
response to extracellular stimulus GO:0009991 116 0.016
positive regulation of signal transduction GO:0009967 223 0.016
steroid catabolic process GO:0006706 1 0.016
regulation of protein metabolic process GO:0051246 256 0.016
nucleotide catabolic process GO:0009166 109 0.016
single organism biosynthetic process GO:0044711 206 0.015
cell proliferation GO:0008283 299 0.015
mitotic g2 m transition checkpoint GO:0044818 70 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
actin filament based process GO:0030029 220 0.015
cellular response to ethanol GO:0071361 4 0.015
amine metabolic process GO:0009308 12 0.015
sterol homeostasis GO:0055092 4 0.015
regulation of proteolysis GO:0030162 87 0.015
positive regulation of signaling GO:0023056 243 0.015
regulation of cell development GO:0060284 215 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
negative regulation of cell communication GO:0010648 223 0.015
negative regulation of cell cycle GO:0045786 116 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
positive regulation of molecular function GO:0044093 136 0.015
regulation of mapk cascade GO:0043408 92 0.015
actin cytoskeleton organization GO:0030036 206 0.015
rna localization GO:0006403 115 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
response to organophosphorus GO:0046683 2 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
ion transport GO:0006811 145 0.014
appendage morphogenesis GO:0035107 397 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
forebrain development GO:0030900 2 0.014
growth GO:0040007 359 0.014
chemosensory behavior GO:0007635 106 0.014
regulation of catalytic activity GO:0050790 185 0.014
chromatin remodeling GO:0006338 72 0.014
exocrine system development GO:0035272 162 0.014
telencephalon development GO:0021537 2 0.014
response to radiation GO:0009314 155 0.014
double strand break repair via homologous recombination GO:0000724 13 0.014
carbohydrate metabolic process GO:0005975 82 0.014
protein complex biogenesis GO:0070271 201 0.014
anterior posterior axis specification GO:0009948 109 0.014
behavioral response to pain GO:0048266 3 0.014
benzene containing compound metabolic process GO:0042537 3 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
kidney development GO:0001822 3 0.014
regulation of anatomical structure size GO:0090066 163 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
ovarian follicle cell development GO:0030707 248 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.014
protein processing GO:0016485 68 0.013
intracellular protein transmembrane transport GO:0065002 4 0.013
establishment of localization in cell GO:0051649 402 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
spindle organization GO:0007051 253 0.013
estrogen metabolic process GO:0008210 1 0.013
stem cell development GO:0048864 79 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
regulation of behavior GO:0050795 75 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
central nervous system development GO:0007417 201 0.013
regulation of response to stress GO:0080134 200 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
ion transmembrane transport GO:0034220 122 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
cell motility GO:0048870 251 0.013
regulation of growth GO:0040008 233 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
compound eye morphogenesis GO:0001745 249 0.013
chromosome separation GO:0051304 42 0.013
single organism membrane organization GO:0044802 93 0.013
aggressive behavior GO:0002118 63 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
defense response to other organism GO:0098542 225 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
response to external biotic stimulus GO:0043207 293 0.012
regulation of nervous system development GO:0051960 248 0.012
actin filament organization GO:0007015 126 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
protein transport GO:0015031 155 0.012
regulation of cell shape GO:0008360 113 0.012
stem cell division GO:0017145 69 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
eggshell chorion assembly GO:0007306 66 0.012
homeostatic process GO:0042592 199 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
sister chromatid segregation GO:0000819 92 0.012
response to lipopolysaccharide GO:0032496 4 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
segmentation GO:0035282 207 0.012
regulation of multi organism process GO:0043900 131 0.012
respiratory system development GO:0060541 213 0.012
regulation of catabolic process GO:0009894 170 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
chorion containing eggshell formation GO:0007304 105 0.012
pigmentation GO:0043473 75 0.012
cellular protein localization GO:0034613 160 0.012
regulation of neurogenesis GO:0050767 158 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
mapk cascade GO:0000165 107 0.012
defense response to bacterium GO:0042742 178 0.012
negative regulation of nervous system development GO:0051961 92 0.012
regulation of localization GO:0032879 275 0.011
protein heterooligomerization GO:0051291 4 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
l glutamate import GO:0051938 1 0.011
positive regulation of cell migration GO:0030335 2 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
protein transmembrane transport GO:0071806 4 0.011
cell cycle checkpoint GO:0000075 95 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
open tracheal system development GO:0007424 204 0.011
eye development GO:0001654 323 0.011
cellular ketone metabolic process GO:0042180 24 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
response to bacterium GO:0009617 198 0.011
synapse organization GO:0050808 196 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
detection of chemical stimulus GO:0009593 93 0.011
negative regulation of signaling GO:0023057 219 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
polyol biosynthetic process GO:0046173 3 0.011
salivary gland morphogenesis GO:0007435 145 0.011
single organism cellular localization GO:1902580 180 0.011
membrane organization GO:0061024 112 0.011
detection of chemical stimulus involved in sensory perception of smell GO:0050911 50 0.011
ras protein signal transduction GO:0007265 88 0.011
olfactory behavior GO:0042048 97 0.011
response to organic cyclic compound GO:0014070 89 0.011
dendrite development GO:0016358 204 0.011
cell death GO:0008219 279 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
sensory organ morphogenesis GO:0090596 260 0.011
connective tissue development GO:0061448 3 0.011
tissue morphogenesis GO:0048729 297 0.011
gland development GO:0048732 191 0.011
response to endogenous stimulus GO:0009719 119 0.011
establishment of protein localization GO:0045184 163 0.011
pigment metabolic process GO:0042440 84 0.011
cytoplasmic transport GO:0016482 130 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
regulation of cell cycle process GO:0010564 181 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
response to pain GO:0048265 3 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
death GO:0016265 284 0.010
regulation of cellular component size GO:0032535 98 0.010
androgen metabolic process GO:0008209 1 0.010
cytokinesis GO:0000910 90 0.010
learning or memory GO:0007611 141 0.010
imaginal disc pattern formation GO:0007447 91 0.010
camera type eye morphogenesis GO:0048593 2 0.010
autophagy GO:0006914 108 0.010
g protein coupled receptor signaling pathway GO:0007186 136 0.010
intracellular protein transmembrane import GO:0044743 4 0.010
endomembrane system organization GO:0010256 119 0.010
positive regulation of cellular component biogenesis GO:0044089 80 0.010
positive regulation of cell motility GO:2000147 3 0.010
mitotic nuclear division GO:0007067 213 0.010
female meiosis chromosome segregation GO:0016321 33 0.010
retina development in camera type eye GO:0060041 4 0.010
detection of external stimulus GO:0009581 66 0.010
response to starvation GO:0042594 97 0.010
long term memory GO:0007616 62 0.010
ribonucleoside monophosphate catabolic process GO:0009158 39 0.010
programmed cell death GO:0012501 257 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
male courtship behavior GO:0008049 63 0.010
cellular response to organic substance GO:0071310 132 0.010

hdm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
disease of metabolism DOID:0014667 0 0.027
inherited metabolic disorder DOID:655 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
cardiovascular system disease DOID:1287 0 0.013
vascular disease DOID:178 0 0.011
nervous system disease DOID:863 0 0.010
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010