Drosophila melanogaster

83 known processes

morgue (Dmel_CG15437)

modifier of rpr and grim, ubiquitously expressed

(Aliases: CG15437,Dmel\CG15437,BcDNA:GH02435,Morgue)

morgue biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein ubiquitination GO:0016567 70 0.692
transcription from rna polymerase ii promoter GO:0006366 368 0.676
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.604
negative regulation of cell cycle process GO:0010948 109 0.604
protein modification by small protein conjugation or removal GO:0070647 106 0.552
positive regulation of rna metabolic process GO:0051254 271 0.532
negative regulation of cell cycle phase transition GO:1901988 103 0.460
positive regulation of cellular biosynthetic process GO:0031328 316 0.448
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.445
sensory organ morphogenesis GO:0090596 260 0.443
protein modification process GO:0036211 438 0.435
response to organic substance GO:0010033 284 0.424
positive regulation of transcription dna templated GO:0045893 266 0.375
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.347
chromatin modification GO:0016568 147 0.306
negative regulation of cell cycle GO:0045786 116 0.306
negative regulation of rna metabolic process GO:0051253 251 0.287
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.277
protein modification by small protein conjugation GO:0032446 79 0.266
regulation of cell cycle GO:0051726 291 0.236
negative regulation of programmed cell death GO:0043069 72 0.221
eye development GO:0001654 323 0.221
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.220
cellular protein modification process GO:0006464 438 0.218
neuron projection guidance GO:0097485 241 0.213
negative regulation of cellular metabolic process GO:0031324 382 0.209
positive regulation of nucleic acid templated transcription GO:1903508 266 0.208
eye morphogenesis GO:0048592 260 0.197
positive regulation of response to stimulus GO:0048584 323 0.192
chromatin organization GO:0006325 207 0.192
cellular response to dna damage stimulus GO:0006974 223 0.190
homeostatic process GO:0042592 199 0.172
negative regulation of mitotic cell cycle GO:0045930 109 0.161
negative regulation of signaling GO:0023057 219 0.161
axonogenesis GO:0007409 290 0.156
central nervous system development GO:0007417 201 0.155
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.152
dorsal ventral pattern formation GO:0009953 133 0.150
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.149
negative regulation of transcription dna templated GO:0045892 237 0.144
regulation of response to external stimulus GO:0032101 115 0.128
organelle fission GO:0048285 340 0.128
positive regulation of gene expression GO:0010628 290 0.124
negative regulation of rna biosynthetic process GO:1902679 240 0.118
peptidyl lysine methylation GO:0018022 16 0.118
negative regulation of biosynthetic process GO:0009890 277 0.110
organic substance catabolic process GO:1901575 308 0.109
negative regulation of response to stimulus GO:0048585 258 0.104
regulation of cellular catabolic process GO:0031329 157 0.104
dna metabolic process GO:0006259 227 0.103
dna integrity checkpoint GO:0031570 81 0.102
mitotic cell cycle checkpoint GO:0007093 88 0.100
cellular response to starvation GO:0009267 61 0.100
dna templated transcription elongation GO:0006354 18 0.098
response to oxygen containing compound GO:1901700 200 0.094
single organism catabolic process GO:0044712 228 0.091
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.088
determination of adult lifespan GO:0008340 137 0.087
regulation of multicellular organismal development GO:2000026 414 0.083
compound eye development GO:0048749 307 0.082
regulation of cellular response to stress GO:0080135 89 0.079
cell cycle checkpoint GO:0000075 95 0.077
cellular response to chemical stimulus GO:0070887 199 0.076
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.076
autophagy GO:0006914 108 0.075
regulation of mitotic cell cycle phase transition GO:1901990 130 0.073
positive regulation of rna biosynthetic process GO:1902680 266 0.073
regulation of protein catabolic process GO:0042176 55 0.072
axon guidance GO:0007411 233 0.071
negative regulation of nucleic acid templated transcription GO:1903507 240 0.071
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.068
organic substance transport GO:0071702 257 0.067
positive regulation of macromolecule metabolic process GO:0010604 405 0.067
response to extracellular stimulus GO:0009991 116 0.067
negative regulation of gene expression GO:0010629 387 0.066
cell maturation GO:0048469 144 0.066
mitotic dna damage checkpoint GO:0044773 74 0.065
taxis GO:0042330 304 0.060
cell proliferation GO:0008283 299 0.059
cellular catabolic process GO:0044248 372 0.059
cellular macromolecular complex assembly GO:0034622 153 0.058
establishment of localization in cell GO:0051649 402 0.058
positive regulation of signal transduction GO:0009967 223 0.058
dna damage checkpoint GO:0000077 78 0.058
growth GO:0040007 359 0.057
regulation of response to stress GO:0080134 200 0.056
cellular protein catabolic process GO:0044257 83 0.054
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.053
regulation of programmed cell death GO:0043067 152 0.053
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.052
cellular response to oxygen containing compound GO:1901701 79 0.050
defense response GO:0006952 300 0.048
regulation of cellular protein metabolic process GO:0032268 243 0.048
nitrogen compound transport GO:0071705 85 0.047
regulation of immune system process GO:0002682 176 0.046
response to starvation GO:0042594 97 0.046
retina development in camera type eye GO:0060041 4 0.045
positive regulation of molecular function GO:0044093 136 0.045
positive regulation of cellular amine metabolic process GO:0033240 0 0.044
multicellular organismal reproductive behavior GO:0033057 110 0.043
catabolic process GO:0009056 409 0.043
response to nutrient levels GO:0031667 114 0.042
positive regulation of biosynthetic process GO:0009891 316 0.041
protein acylation GO:0043543 42 0.041
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.040
chemotaxis GO:0006935 249 0.040
macromolecular complex assembly GO:0065003 256 0.040
negative regulation of signal transduction GO:0009968 206 0.039
mitotic spindle organization GO:0007052 220 0.039
camera type eye development GO:0043010 4 0.038
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.038
dendrite development GO:0016358 204 0.038
regulation of gene silencing GO:0060968 63 0.038
apoptotic signaling pathway GO:0097190 27 0.037
cellular nitrogen compound catabolic process GO:0044270 165 0.037
hemopoiesis GO:0030097 46 0.037
regulation of cysteine type endopeptidase activity GO:2000116 27 0.034
regulation of apoptotic process GO:0042981 130 0.034
cell death GO:0008219 279 0.034
nucleobase containing compound catabolic process GO:0034655 165 0.034
developmental programmed cell death GO:0010623 138 0.034
peptidyl amino acid modification GO:0018193 105 0.033
regulation of proteolysis GO:0030162 87 0.032
negative regulation of multicellular organismal process GO:0051241 142 0.032
embryonic organ development GO:0048568 50 0.031
positive regulation of cell communication GO:0010647 250 0.031
gene silencing GO:0016458 138 0.031
regulation of cell cycle phase transition GO:1901987 130 0.030
cell cycle phase transition GO:0044770 140 0.030
negative regulation of gene expression epigenetic GO:0045814 77 0.030
nucleus organization GO:0006997 45 0.030
nucleosome organization GO:0034728 59 0.030
regionalization GO:0003002 416 0.030
histone deacetylation GO:0016575 9 0.029
negative regulation of cellular protein metabolic process GO:0032269 85 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.029
single organism intracellular transport GO:1902582 207 0.028
glycosyl compound catabolic process GO:1901658 112 0.028
positive regulation of catalytic activity GO:0043085 118 0.028
regulation of cell differentiation GO:0045595 302 0.027
protein complex biogenesis GO:0070271 201 0.027
mitotic cell cycle phase transition GO:0044772 138 0.027
regulation of protein modification process GO:0031399 112 0.027
immune system process GO:0002376 347 0.027
oocyte construction GO:0007308 112 0.027
negative regulation of cell proliferation GO:0008285 69 0.027
protein modification by small protein removal GO:0070646 28 0.026
photoreceptor cell differentiation GO:0046530 170 0.026
dorsal ventral axis specification GO:0009950 66 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
cellular response to abiotic stimulus GO:0071214 58 0.026
embryo development ending in birth or egg hatching GO:0009792 152 0.026
stem cell proliferation GO:0072089 88 0.026
negative regulation of cell differentiation GO:0045596 143 0.025
regulation of catabolic process GO:0009894 170 0.025
cellular response to organic substance GO:0071310 132 0.025
regulation of molecular function GO:0065009 217 0.025
mitotic dna integrity checkpoint GO:0044774 75 0.025
negative regulation of apoptotic process GO:0043066 63 0.025
mitotic g2 dna damage checkpoint GO:0007095 69 0.024
multicellular organismal aging GO:0010259 140 0.024
negative regulation of cell communication GO:0010648 223 0.024
positive regulation of apoptotic signaling pathway GO:2001235 4 0.024
meiotic nuclear division GO:0007126 151 0.024
ubiquitin dependent protein catabolic process GO:0006511 78 0.024
axon development GO:0061564 297 0.024
feeding behavior GO:0007631 50 0.023
nucleoside triphosphate metabolic process GO:0009141 120 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
histone modification GO:0016570 106 0.023
regulation of cell proliferation GO:0042127 163 0.023
nuclear division GO:0000280 332 0.023
purine ribonucleotide catabolic process GO:0009154 109 0.022
secretion GO:0046903 109 0.022
regulation of intracellular signal transduction GO:1902531 236 0.022
stem cell differentiation GO:0048863 117 0.022
negative regulation of cell division GO:0051782 17 0.022
intracellular signal transduction GO:0035556 300 0.022
multi multicellular organism process GO:0044706 123 0.022
positive regulation of protein metabolic process GO:0051247 128 0.021
detection of stimulus GO:0051606 156 0.021
positive regulation of transport GO:0051050 92 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.020
axis specification GO:0009798 167 0.020
neuroblast proliferation GO:0007405 74 0.019
nucleocytoplasmic transport GO:0006913 72 0.019
positive regulation of proteolysis GO:0045862 52 0.019
regulation of autophagy GO:0010506 62 0.019
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.019
regulation of protein metabolic process GO:0051246 256 0.019
tissue death GO:0016271 102 0.019
trna transcription from rna polymerase iii promoter GO:0042797 1 0.019
endocytosis GO:0006897 310 0.018
proteolysis GO:0006508 192 0.018
carbohydrate metabolic process GO:0005975 82 0.018
vesicle mediated transport GO:0016192 381 0.018
digestive tract development GO:0048565 149 0.018
chromatin remodeling GO:0006338 72 0.018
oocyte dorsal ventral axis specification GO:0007310 34 0.018
regulation of localization GO:0032879 275 0.018
cytoplasmic transport GO:0016482 130 0.017
positive regulation of signaling GO:0023056 243 0.017
organic acid metabolic process GO:0006082 103 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
guanosine containing compound metabolic process GO:1901068 74 0.016
intracellular transport GO:0046907 228 0.016
regulation of protein ubiquitination GO:0031396 22 0.016
peptidyl lysine modification GO:0018205 57 0.016
protein acetylation GO:0006473 39 0.016
macromolecule catabolic process GO:0009057 161 0.016
dna replication GO:0006260 48 0.016
oocyte development GO:0048599 124 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.015
chromatin silencing GO:0006342 76 0.015
regulation of cell death GO:0010941 173 0.015
brain development GO:0007420 120 0.015
negative regulation of growth GO:0045926 84 0.015
muscle structure development GO:0061061 224 0.015
histone exchange GO:0043486 21 0.015
camera type eye morphogenesis GO:0048593 2 0.014
death GO:0016265 284 0.014
cell cycle arrest GO:0007050 4 0.014
branched chain amino acid transport GO:0015803 3 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
chromosome organization GO:0051276 360 0.014
cellular response to nutrient levels GO:0031669 62 0.014
meiotic cell cycle process GO:1903046 132 0.014
dna biosynthetic process GO:0071897 24 0.013
regulation of cell development GO:0060284 215 0.013
macromolecule deacylation GO:0098732 11 0.013
protein deacetylation GO:0006476 9 0.013
negative regulation of proteolysis GO:0045861 31 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
stem cell division GO:0017145 69 0.013
response to biotic stimulus GO:0009607 294 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
negative regulation of immune system process GO:0002683 50 0.012
immune response GO:0006955 246 0.012
regulation of immune response GO:0050776 118 0.012
cellular response to external stimulus GO:0071496 66 0.012
regulation of catalytic activity GO:0050790 185 0.012
dendrite morphogenesis GO:0048813 199 0.012
small molecule metabolic process GO:0044281 305 0.011
lateral inhibition GO:0046331 206 0.011
regulation of transport GO:0051049 181 0.011
response to other organism GO:0051707 293 0.011
mitotic g2 m transition checkpoint GO:0044818 70 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
negative regulation of notch signaling pathway GO:0045746 41 0.011
programmed cell death GO:0012501 257 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
leg disc development GO:0035218 92 0.011
regulation of growth GO:0040008 233 0.011
protein complex assembly GO:0006461 200 0.011
protein maturation GO:0051604 71 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
cellular response to extracellular stimulus GO:0031668 64 0.011
defense response to bacterium GO:0042742 178 0.010
response to temperature stimulus GO:0009266 106 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
regulation of protein deacetylation GO:0090311 2 0.010
protein dna complex subunit organization GO:0071824 86 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
locomotory behavior GO:0007626 176 0.010
regulation of protein stability GO:0031647 43 0.010
response to abiotic stimulus GO:0009628 341 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
positive regulation of growth GO:0045927 75 0.010
compound eye morphogenesis GO:0001745 249 0.010
aromatic compound catabolic process GO:0019439 166 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010

morgue disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.016