Drosophila melanogaster

39 known processes

RpII215 (Dmel_CG1554)

RNA polymerase II 215kD subunit

(Aliases: RNA Pol II,dRPB1,RNAPII0,Pol IIo[ser2],Pol II0[ser5],CTD,Pol-IIa,RNA pol IIo,RpII,pol II,RNA pol II,l(1)DF912,RPB1,RNApolII,RNAP,RNAP II,POL,RNA polII,5,Ubl,CG1554,PolII,Pol IIo,RNAP II LS,l(1)10Ca,Pol IIa,l(1)DC912,II,Rpll215,L5,RNAPII,Pol II CTD,l(1)G0040,Pol IIo[ser5],polII,Rpb1,8WG16,H5,RNA PolII,Dmel\CG1554,RNA Pol II CTD,l(1)L5,Pol II0[ser2],PolIIo,Pol II)

RpII215 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 405 0.851
Human
protein targeting to nucleus GO:0044744 51 0.849
negative regulation of cellular biosynthetic process GO:0031327 277 0.795
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.646
response to oxygen containing compound GO:1901700 200 0.610
response to organic substance GO:0010033 284 0.607
immune response GO:0006955 246 0.563
positive regulation of rna biosynthetic process GO:1902680 266 0.557
vesicle mediated transport GO:0016192 381 0.528
cellular response to dna damage stimulus GO:0006974 223 0.523
positive regulation of transcription dna templated GO:0045893 266 0.465
response to radiation GO:0009314 155 0.457
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.456
intracellular protein transport GO:0006886 104 0.442
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.438
response to other organism GO:0051707 293 0.437
negative regulation of biosynthetic process GO:0009890 277 0.414
transcription from rna polymerase ii promoter GO:0006366 368 0.413
Human Yeast Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.401
Worm
response to biotic stimulus GO:0009607 294 0.400
regulation of protein metabolic process GO:0051246 256 0.376
regulation of mrna 3 end processing GO:0031440 7 0.371
regulation of cellular protein metabolic process GO:0032268 243 0.355
response to abiotic stimulus GO:0009628 341 0.349
spermatogenesis GO:0007283 200 0.338
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.336
larval development GO:0002164 104 0.310
Worm
mitotic cell cycle phase transition GO:0044772 138 0.308
stem cell differentiation GO:0048863 117 0.306
negative regulation of rna biosynthetic process GO:1902679 240 0.303
nuclear transport GO:0051169 72 0.299
mrna metabolic process GO:0016071 124 0.294
regulation of phosphorus metabolic process GO:0051174 210 0.292
positive regulation of cellular biosynthetic process GO:0031328 316 0.278
negative regulation of nucleic acid templated transcription GO:1903507 240 0.269
defense response GO:0006952 300 0.269
organelle assembly GO:0070925 198 0.254
regulation of dna templated transcription elongation GO:0032784 17 0.246
positive regulation of biosynthetic process GO:0009891 316 0.244
negative regulation of cellular metabolic process GO:0031324 382 0.242
cellular macromolecule localization GO:0070727 220 0.218
nucleocytoplasmic transport GO:0006913 72 0.218
regulation of phosphate metabolic process GO:0019220 210 0.218
posttranscriptional regulation of gene expression GO:0010608 145 0.212
regulation of cell cycle phase transition GO:1901987 130 0.206
endocytosis GO:0006897 310 0.204
negative regulation of rna metabolic process GO:0051253 251 0.204
regionalization GO:0003002 416 0.201
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.200
mitotic spindle organization GO:0007052 220 0.193
Worm
muscle structure development GO:0061061 224 0.190
organic substance transport GO:0071702 257 0.183
establishment of localization in cell GO:0051649 402 0.182
regulation of protein modification process GO:0031399 112 0.178
spindle organization GO:0007051 253 0.176
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.176
protein import into nucleus GO:0006606 51 0.175
negative regulation of transcription dna templated GO:0045892 237 0.173
negative regulation of gene expression GO:0010629 387 0.170
regulation of gene expression epigenetic GO:0040029 128 0.164
regulation of response to stress GO:0080134 200 0.160
protein import GO:0017038 55 0.159
positive regulation of cellular protein metabolic process GO:0032270 118 0.159
male gamete generation GO:0048232 201 0.158
response to external biotic stimulus GO:0043207 293 0.157
positive regulation of protein metabolic process GO:0051247 128 0.156
regulation of mrna metabolic process GO:1903311 72 0.154
cell migration GO:0016477 238 0.151
positive regulation of nucleic acid templated transcription GO:1903508 266 0.150
nucleoside triphosphate catabolic process GO:0009143 108 0.143
small molecule metabolic process GO:0044281 305 0.141
regulation of nucleocytoplasmic transport GO:0046822 35 0.139
establishment of protein localization to organelle GO:0072594 62 0.134
skin development GO:0043588 65 0.134
stem cell development GO:0048864 79 0.132
response to light stimulus GO:0009416 124 0.131
regulation of transport GO:0051049 181 0.131
neurological system process GO:0050877 358 0.129
aromatic compound catabolic process GO:0019439 166 0.129
rna splicing GO:0008380 83 0.125
Human
regulation of mrna processing GO:0050684 71 0.122
chromosome organization GO:0051276 360 0.122
appendage development GO:0048736 401 0.122
cellular nitrogen compound catabolic process GO:0044270 165 0.120
cellular response to chemical stimulus GO:0070887 199 0.119
positive regulation of rna metabolic process GO:0051254 271 0.119
Human
positive regulation of gene expression GO:0010628 290 0.117
Human
cellular protein localization GO:0034613 160 0.117
regulation of defense response GO:0031347 102 0.117
response to heat GO:0009408 63 0.117
single organism intracellular transport GO:1902582 207 0.116
cellular response to oxygen containing compound GO:1901701 79 0.116
female germ line cyst formation GO:0048135 42 0.114
stem cell maintenance GO:0019827 67 0.110
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.108
Human
mrna transport GO:0051028 15 0.108
dna templated transcription elongation GO:0006354 18 0.107
nuclear import GO:0051170 51 0.107
regulation of cellular ketone metabolic process GO:0010565 3 0.106
multi organism behavior GO:0051705 175 0.105
protein localization GO:0008104 284 0.104
axis specification GO:0009798 167 0.104
spermatid differentiation GO:0048515 114 0.103
nuclear division GO:0000280 332 0.101
Worm
ribonucleoprotein complex assembly GO:0022618 23 0.101
chromatin organization GO:0006325 207 0.100
response to bacterium GO:0009617 198 0.099
regulation of microtubule cytoskeleton organization GO:0070507 41 0.096
innate immune response GO:0045087 144 0.095
mitotic nuclear division GO:0007067 213 0.095
Worm
cell maturation GO:0048469 144 0.095
protein localization to organelle GO:0033365 82 0.095
negative regulation of multicellular organismal process GO:0051241 142 0.095
positive regulation of molecular function GO:0044093 136 0.094
protein complex assembly GO:0006461 200 0.094
biological adhesion GO:0022610 138 0.093
germarium derived egg chamber formation GO:0007293 101 0.093
regulation of cellular component biogenesis GO:0044087 201 0.091
chromatin modification GO:0016568 147 0.090
growth GO:0040007 359 0.089
mrna processing GO:0006397 104 0.087
protein targeting GO:0006605 64 0.085
protein localization to nucleus GO:0034504 55 0.084
establishment of rna localization GO:0051236 47 0.083
ribonucleotide catabolic process GO:0009261 109 0.083
regulation of intracellular protein transport GO:0033157 46 0.083
response to organonitrogen compound GO:0010243 75 0.082
amine metabolic process GO:0009308 12 0.081
ribonucleoprotein complex subunit organization GO:0071826 28 0.080
cell cell junction organization GO:0045216 55 0.079
defense response to other organism GO:0098542 225 0.079
organophosphate metabolic process GO:0019637 195 0.079
nucleobase containing compound catabolic process GO:0034655 165 0.078
multicellular organismal reproductive behavior GO:0033057 110 0.077
negative regulation of protein metabolic process GO:0051248 85 0.073
nucleobase containing small molecule metabolic process GO:0055086 174 0.073
response to alcohol GO:0097305 95 0.072
cytoplasmic transport GO:0016482 130 0.072
single organism cellular localization GO:1902580 180 0.072
negative regulation of mitotic cell cycle GO:0045930 109 0.071
rna processing GO:0006396 147 0.071
Human
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.071
body morphogenesis GO:0010171 2 0.071
negative regulation of immune system process GO:0002683 50 0.071
organelle localization GO:0051640 148 0.071
central nervous system development GO:0007417 201 0.070
purine containing compound catabolic process GO:0072523 112 0.070
single organism nuclear import GO:1902593 51 0.070
heterocycle catabolic process GO:0046700 166 0.069
cell proliferation GO:0008283 299 0.069
regulation of localization GO:0032879 275 0.068
carbohydrate derivative catabolic process GO:1901136 118 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.067
Human
rna localization GO:0006403 115 0.066
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.065
organonitrogen compound catabolic process GO:1901565 128 0.064
oocyte development GO:0048599 124 0.063
imaginal disc derived appendage morphogenesis GO:0035114 395 0.063
cell division GO:0051301 248 0.063
Worm
organic cyclic compound catabolic process GO:1901361 168 0.062
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.062
regulation of mitotic cell cycle GO:0007346 190 0.061
adult behavior GO:0030534 137 0.061
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.059
dna repair GO:0006281 54 0.056
Yeast
rna polyadenylation GO:0043631 12 0.056
nitrogen compound transport GO:0071705 85 0.056
histone modification GO:0016570 106 0.055
nucleoside catabolic process GO:0009164 112 0.054
purine ribonucleotide catabolic process GO:0009154 109 0.054
covalent chromatin modification GO:0016569 106 0.054
heart development GO:0007507 82 0.054
regulation of organelle organization GO:0033043 196 0.053
regulation of cell differentiation GO:0045595 302 0.053
photoreceptor cell differentiation GO:0046530 170 0.053
nucleoside metabolic process GO:0009116 127 0.053
regulation of cellular amino acid metabolic process GO:0006521 0 0.052
single organism behavior GO:0044708 391 0.051
intracellular transport GO:0046907 228 0.051
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.051
purine nucleotide metabolic process GO:0006163 146 0.051
chromatin remodeling GO:0006338 72 0.050
regulation of intracellular transport GO:0032386 64 0.050
peptidyl amino acid modification GO:0018193 105 0.049
purine nucleotide catabolic process GO:0006195 109 0.049
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.049
macromolecular complex assembly GO:0065003 256 0.046
defense response to gram negative bacterium GO:0050829 94 0.045
pole plasm mrna localization GO:0019094 49 0.044
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.044
positive regulation of response to stimulus GO:0048584 323 0.044
response to nitrogen compound GO:1901698 90 0.043
response to endogenous stimulus GO:0009719 119 0.043
regulation of transferase activity GO:0051338 58 0.043
gliogenesis GO:0042063 80 0.043
regulation of protein phosphorylation GO:0001932 64 0.042
oocyte microtubule cytoskeleton organization GO:0016325 35 0.042
rna 3 end processing GO:0031123 45 0.041
maintenance of location GO:0051235 73 0.041
cellular amino acid metabolic process GO:0006520 61 0.041
regulation of protein import into nucleus GO:0042306 28 0.041
epidermis development GO:0008544 65 0.041
dna damage checkpoint GO:0000077 78 0.040
purine ribonucleoside metabolic process GO:0046128 127 0.040
germarium derived female germ line cyst formation GO:0030727 42 0.040
protein transport GO:0015031 155 0.040
regulation of innate immune response GO:0045088 71 0.040
mrna 3 end processing GO:0031124 28 0.040
positive regulation of intracellular transport GO:0032388 42 0.039
positive regulation of cell proliferation GO:0008284 47 0.038
segmentation GO:0035282 207 0.038
cell cell signaling involved in cell fate commitment GO:0045168 210 0.038
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.037
purine nucleoside triphosphate metabolic process GO:0009144 119 0.037
regulation of cytoplasmic transport GO:1903649 47 0.037
wing disc morphogenesis GO:0007472 344 0.036
cellular ketone metabolic process GO:0042180 24 0.036
regulation of cellular localization GO:0060341 136 0.036
mitotic dna damage checkpoint GO:0044773 74 0.036
nucleotide metabolic process GO:0009117 161 0.036
negative regulation of transcription factor import into nucleus GO:0042992 4 0.035
anterior posterior pattern specification GO:0009952 136 0.035
cell junction assembly GO:0034329 42 0.035
negative regulation of cellular protein metabolic process GO:0032269 85 0.034
epidermal cell differentiation GO:0009913 51 0.034
post embryonic appendage morphogenesis GO:0035120 385 0.034
cellular amine metabolic process GO:0044106 12 0.034
dendrite development GO:0016358 204 0.034
positive regulation of catabolic process GO:0009896 105 0.033
regulation of microtubule based process GO:0032886 49 0.033
reproductive system development GO:0061458 74 0.033
appendage morphogenesis GO:0035107 397 0.032
positive regulation of cell motility GO:2000147 3 0.032
defense response to bacterium GO:0042742 178 0.032
regulation of multi organism process GO:0043900 131 0.032
establishment of protein localization GO:0045184 163 0.031
lipid localization GO:0010876 54 0.031
nuclear export GO:0051168 24 0.031
purine nucleoside catabolic process GO:0006152 112 0.031
purine ribonucleotide metabolic process GO:0009150 145 0.030
ribonucleotide metabolic process GO:0009259 145 0.030
cellular response to abiotic stimulus GO:0071214 58 0.030
myofibril assembly GO:0030239 36 0.030
organonitrogen compound metabolic process GO:1901564 318 0.029
regulation of epidermal cell differentiation GO:0045604 3 0.029
regulation of molecular function GO:0065009 217 0.029
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.028
gonad development GO:0008406 50 0.028
regulation of protein localization to nucleus GO:1900180 29 0.028
regulation of immune system process GO:0002682 176 0.028
dendrite morphogenesis GO:0048813 199 0.027
positive regulation of defense response GO:0031349 59 0.027
phosphorylation GO:0016310 294 0.027
dorsal ventral pattern formation GO:0009953 133 0.027
positive regulation of developmental growth GO:0048639 62 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
positive regulation of cellular component organization GO:0051130 156 0.027
axon guidance GO:0007411 233 0.027
carboxylic acid metabolic process GO:0019752 92 0.026
nucleobase containing compound transport GO:0015931 56 0.026
cellular protein complex assembly GO:0043623 71 0.025
negative regulation of phosphorus metabolic process GO:0010563 45 0.025
lateral inhibition GO:0046331 206 0.025
cellular component assembly involved in morphogenesis GO:0010927 151 0.025
telencephalon development GO:0021537 2 0.024
developmental growth GO:0048589 280 0.024
g1 s transition of mitotic cell cycle GO:0000082 31 0.024
regulation of catalytic activity GO:0050790 185 0.024
protein complex disassembly GO:0043241 36 0.023
ribonucleoside triphosphate catabolic process GO:0009203 108 0.023
nucleoside phosphate catabolic process GO:1901292 110 0.023
aging GO:0007568 143 0.023
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.022
negative regulation of developmental process GO:0051093 201 0.022
positive regulation of mitotic cell cycle GO:0045931 34 0.022
response to lipopolysaccharide GO:0032496 4 0.022
hindbrain development GO:0030902 2 0.022
protein modification process GO:0036211 438 0.022
Worm
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
organic substance catabolic process GO:1901575 308 0.022
actomyosin structure organization GO:0031032 56 0.021
regulation of phosphorylation GO:0042325 147 0.021
axon development GO:0061564 297 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
axonogenesis GO:0007409 290 0.021
regulation of nucleobase containing compound transport GO:0032239 4 0.020
nucleoside triphosphate metabolic process GO:0009141 120 0.020
immune response activating signal transduction GO:0002757 2 0.020
ribonucleoside triphosphate metabolic process GO:0009199 119 0.020
regulation of cytoskeleton organization GO:0051493 89 0.020
regulation of protein stability GO:0031647 43 0.020
cell adhesion GO:0007155 136 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
protein complex biogenesis GO:0070271 201 0.020
regulation of protein polymerization GO:0032271 28 0.019
cognition GO:0050890 141 0.019
nitric oxide metabolic process GO:0046209 1 0.019
cell junction organization GO:0034330 57 0.019
sex differentiation GO:0007548 81 0.019
positive regulation of signaling GO:0023056 243 0.019
positive regulation of signal transduction GO:0009967 223 0.018
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
regulation of embryonic pattern specification GO:1902875 27 0.018
positive regulation of cell cycle GO:0045787 43 0.018
multicellular organismal aging GO:0010259 140 0.018
localization of cell GO:0051674 257 0.018
negative regulation of cell cycle GO:0045786 116 0.018
response to wounding GO:0009611 94 0.018
histone h3 acetylation GO:0043966 11 0.017
chromatin silencing GO:0006342 76 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
negative regulation of organelle organization GO:0010639 56 0.017
nucleic acid transport GO:0050657 46 0.017
cell cycle g1 s phase transition GO:0044843 31 0.017
mrna polyadenylation GO:0006378 11 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
prostaglandin biosynthetic process GO:0001516 1 0.017
organophosphate catabolic process GO:0046434 112 0.017
oxoacid metabolic process GO:0043436 103 0.017
intracellular signal transduction GO:0035556 300 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.016
cellular response to organic substance GO:0071310 132 0.016
homeostatic process GO:0042592 199 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
negative regulation of cell communication GO:0010648 223 0.016
protein phosphorylation GO:0006468 169 0.016
heart morphogenesis GO:0003007 32 0.016
muscle organ development GO:0007517 127 0.016
meiotic spindle organization GO:0000212 36 0.016
purine containing compound metabolic process GO:0072521 155 0.016
positive regulation of phosphorylation GO:0042327 87 0.016
positive regulation of immune response GO:0050778 63 0.015
regulation of cell death GO:0010941 173 0.015
regulation of pole plasm oskar mrna localization GO:0007317 27 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
histone methylation GO:0016571 40 0.015
positive regulation of protein modification process GO:0031401 58 0.015
lipid storage GO:0019915 38 0.015
meiotic cell cycle GO:0051321 171 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
rna catabolic process GO:0006401 37 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
multi multicellular organism process GO:0044706 123 0.014
positive regulation of dna templated transcription elongation GO:0032786 11 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.013
positive regulation of immune system process GO:0002684 68 0.013
macromolecule methylation GO:0043414 45 0.013
Worm
positive regulation of innate immune response GO:0045089 38 0.013
muscle cell development GO:0055001 50 0.013
mrna splicing via spliceosome GO:0000398 73 0.013
oocyte differentiation GO:0009994 145 0.013
germ line cyst formation GO:0048134 44 0.013
regulation of protein localization GO:0032880 76 0.013
alternative mrna splicing via spliceosome GO:0000380 60 0.013
protein methylation GO:0006479 43 0.013
Worm
regulation of notch signaling pathway GO:0008593 100 0.013
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.013
regulation of protein kinase activity GO:0045859 51 0.013
gene silencing GO:0016458 138 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
regulation of developmental growth GO:0048638 174 0.013
translation GO:0006412 69 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
defense response to virus GO:0051607 23 0.012
blastoderm segmentation GO:0007350 159 0.012
developmental maturation GO:0021700 172 0.012
mitochondrial membrane organization GO:0007006 3 0.012
circulatory system development GO:0072359 82 0.012
cell cycle phase transition GO:0044770 140 0.012
death GO:0016265 284 0.012
positive regulation of intracellular protein transport GO:0090316 30 0.012
positive regulation of protein phosphorylation GO:0001934 34 0.012
regulation of immune response GO:0050776 118 0.012
response to organic cyclic compound GO:0014070 89 0.012
negative regulation of immune response GO:0050777 39 0.012
regulation of cell cycle process GO:0010564 181 0.012
activation of innate immune response GO:0002218 4 0.011
meiotic cell cycle process GO:1903046 132 0.011
histone deubiquitination GO:0016578 8 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
regulation of protein transport GO:0051223 57 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
juvenile hormone mediated signaling pathway GO:0035626 3 0.011
histone lysine methylation GO:0034968 32 0.011
negative regulation of translation GO:0017148 28 0.011
regulation of cell proliferation GO:0042127 163 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
positive regulation of cell communication GO:0010647 250 0.011
regulation of response to dna damage stimulus GO:2001020 23 0.011
macromolecule catabolic process GO:0009057 161 0.011
intracellular receptor signaling pathway GO:0030522 19 0.011
mapk cascade GO:0000165 107 0.011
chromatin mediated maintenance of transcription GO:0048096 7 0.011
response to hypoxia GO:0001666 53 0.011
cell death GO:0008219 279 0.011
cellular response to organonitrogen compound GO:0071417 36 0.011
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.010
positive regulation of developmental process GO:0051094 143 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
posttranscriptional gene silencing by rna GO:0035194 45 0.010
male mating behavior GO:0060179 70 0.010
response to temperature stimulus GO:0009266 106 0.010
regulation of hydrolase activity GO:0051336 97 0.010
glycosyl compound metabolic process GO:1901657 127 0.010

RpII215 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015