Drosophila melanogaster

31 known processes

rod (Dmel_CG1569)

rough deal

(Aliases: EP3408,Rod,ROD,CG1569,Dmel\CG1569,pNB20A)

rod biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 340 0.947
spindle assembly involved in mitosis GO:0090307 50 0.825
centrosome organization GO:0051297 163 0.654
centrosome cycle GO:0007098 137 0.488
mitotic sister chromatid segregation GO:0000070 87 0.460
organelle assembly GO:0070925 198 0.379
negative regulation of cellular biosynthetic process GO:0031327 277 0.350
neural precursor cell proliferation GO:0061351 75 0.318
mitotic nuclear division GO:0007067 213 0.318
chromosome organization GO:0051276 360 0.312
asymmetric neuroblast division GO:0055059 33 0.287
regulation of neuron differentiation GO:0045664 103 0.284
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.276
cell cell signaling involved in cell fate commitment GO:0045168 210 0.268
negative regulation of cellular metabolic process GO:0031324 382 0.260
negative regulation of cell cycle process GO:0010948 109 0.239
Human
lateral inhibition GO:0046331 206 0.238
microtubule organizing center organization GO:0031023 168 0.238
negative regulation of gene expression GO:0010629 387 0.222
dna replication GO:0006260 48 0.218
nuclear dna replication GO:0033260 1 0.210
mitotic spindle organization GO:0007052 220 0.208
sister chromatid segregation GO:0000819 92 0.206
regulation of mitotic cell cycle GO:0007346 190 0.203
Human Worm
dna packaging GO:0006323 91 0.200
negative regulation of cell cycle GO:0045786 116 0.193
Human
nuclear division GO:0000280 332 0.185
cell proliferation GO:0008283 299 0.183
centriole replication GO:0007099 24 0.176
protein complex biogenesis GO:0070271 201 0.155
dna endoreduplication GO:0042023 22 0.154
cellular protein modification process GO:0006464 438 0.151
regulation of localization GO:0032879 275 0.150
Worm
cellular macromolecular complex assembly GO:0034622 153 0.147
chromosome segregation GO:0007059 157 0.146
regulation of cell development GO:0060284 215 0.142
protein phosphorylation GO:0006468 169 0.129
regulation of mitotic cell cycle phase transition GO:1901990 130 0.124
Human
centrosome separation GO:0051299 20 0.122
cell cycle phase transition GO:0044770 140 0.121
Human
negative regulation of biosynthetic process GO:0009890 277 0.121
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.120
ras protein signal transduction GO:0007265 88 0.119
regulation of chromatin silencing GO:0031935 36 0.117
protein complex assembly GO:0006461 200 0.116
negative regulation of mitotic cell cycle GO:0045930 109 0.109
Human
macromolecular complex assembly GO:0065003 256 0.108
regulation of phosphate metabolic process GO:0019220 210 0.106
protein dna complex assembly GO:0065004 63 0.103
negative regulation of rna metabolic process GO:0051253 251 0.097
regulation of molecular function GO:0065009 217 0.095
negative regulation of transcription dna templated GO:0045892 237 0.095
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.091
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.091
negative regulation of signal transduction GO:0009968 206 0.089
cell maturation GO:0048469 144 0.087
chromosome condensation GO:0030261 41 0.086
negative regulation of rna biosynthetic process GO:1902679 240 0.084
cellular macromolecule localization GO:0070727 220 0.084
regulation of nervous system development GO:0051960 248 0.080
regulation of neuron projection development GO:0010975 69 0.077
photoreceptor cell differentiation GO:0046530 170 0.076
phosphorylation GO:0016310 294 0.076
heterocycle catabolic process GO:0046700 166 0.073
dna conformation change GO:0071103 105 0.073
intracellular signal transduction GO:0035556 300 0.071
meiotic nuclear division GO:0007126 151 0.070
regulation of cell differentiation GO:0045595 302 0.067
germ line cyst formation GO:0048134 44 0.067
regulation of anatomical structure morphogenesis GO:0022603 242 0.067
negative regulation of cellular component organization GO:0051129 108 0.067
spindle organization GO:0007051 253 0.066
negative regulation of cellular protein metabolic process GO:0032269 85 0.061
response to abiotic stimulus GO:0009628 341 0.059
regulation of catalytic activity GO:0050790 185 0.057
metaphase anaphase transition of cell cycle GO:0044784 28 0.057
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.055
Worm
regulation of cellular ketone metabolic process GO:0010565 3 0.055
mitotic spindle stabilization GO:0043148 6 0.055
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.054
axonogenesis GO:0007409 290 0.051
mitotic sister chromatid separation GO:0051306 30 0.051
regulation of small gtpase mediated signal transduction GO:0051056 93 0.051
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.051
regulation of mitotic sister chromatid segregation GO:0033047 28 0.048
Worm
response to organic substance GO:0010033 284 0.048
axon development GO:0061564 297 0.046
cell division GO:0051301 248 0.046
Worm
small molecule metabolic process GO:0044281 305 0.045
regulation of ras protein signal transduction GO:0046578 93 0.045
regulation of chromosome segregation GO:0051983 32 0.044
Worm
mitotic chromosome condensation GO:0007076 22 0.044
regulation of neurogenesis GO:0050767 158 0.044
cell projection assembly GO:0030031 94 0.043
protein polymerization GO:0051258 42 0.043
purine ribonucleotide catabolic process GO:0009154 109 0.042
regulation of hydrolase activity GO:0051336 97 0.042
neuroblast proliferation GO:0007405 74 0.042
cellular catabolic process GO:0044248 372 0.041
centriole assembly GO:0098534 24 0.041
centriole centriole cohesion GO:0010457 5 0.041
dna amplification GO:0006277 11 0.041
eye photoreceptor cell differentiation GO:0001754 145 0.041
rho protein signal transduction GO:0007266 14 0.040
small gtpase mediated signal transduction GO:0007264 88 0.039
regulation of organelle organization GO:0033043 196 0.039
Worm
mitotic spindle elongation GO:0000022 81 0.039
endocytosis GO:0006897 310 0.039
regulation of mitotic spindle organization GO:0060236 9 0.039
regulation of cellular protein metabolic process GO:0032268 243 0.038
regulation of cell size GO:0008361 63 0.038
regulation of phosphorus metabolic process GO:0051174 210 0.038
actin filament organization GO:0007015 126 0.038
oxoacid metabolic process GO:0043436 103 0.038
cellular protein complex assembly GO:0043623 71 0.038
dna metabolic process GO:0006259 227 0.037
negative regulation of molecular function GO:0044092 51 0.037
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.036
amine metabolic process GO:0009308 12 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.036
regulation of cellular component size GO:0032535 98 0.036
mitotic sister chromatid cohesion GO:0007064 6 0.035
oocyte maturation GO:0001556 3 0.035
single organism biosynthetic process GO:0044711 206 0.034
single organism cellular localization GO:1902580 180 0.034
axon guidance GO:0007411 233 0.034
organophosphate metabolic process GO:0019637 195 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.033
negative regulation of organelle organization GO:0010639 56 0.033
regulation of cell morphogenesis GO:0022604 163 0.032
mitotic centrosome separation GO:0007100 8 0.031
regulation of cell cycle phase transition GO:1901987 130 0.031
Human
organic substance transport GO:0071702 257 0.031
response to ionizing radiation GO:0010212 32 0.031
muscle structure development GO:0061061 224 0.031
somatic stem cell division GO:0048103 37 0.031
purine nucleotide metabolic process GO:0006163 146 0.030
protein transport GO:0015031 155 0.030
organic substance catabolic process GO:1901575 308 0.030
negative regulation of gene expression epigenetic GO:0045814 77 0.030
eye morphogenesis GO:0048592 260 0.030
actin cytoskeleton organization GO:0030036 206 0.030
eye photoreceptor cell development GO:0042462 81 0.029
death GO:0016265 284 0.029
protein dna complex subunit organization GO:0071824 86 0.029
asymmetric stem cell division GO:0098722 49 0.029
regulation of cell projection organization GO:0031344 92 0.028
dna dependent dna replication GO:0006261 17 0.028
compound eye photoreceptor cell differentiation GO:0001751 140 0.028
regulation of developmental growth GO:0048638 174 0.028
negative regulation of ras protein signal transduction GO:0046580 13 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.027
vesicle mediated transport GO:0016192 381 0.027
cell cycle g1 s phase transition GO:0044843 31 0.027
male meiosis cytokinesis GO:0007112 26 0.026
negative regulation of catalytic activity GO:0043086 42 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
dna geometric change GO:0032392 16 0.026
cellular amine metabolic process GO:0044106 12 0.025
cellular protein localization GO:0034613 160 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
spindle assembly GO:0051225 80 0.025
nucleotide metabolic process GO:0009117 161 0.024
purine ribonucleoside catabolic process GO:0046130 112 0.024
regulation of proteolysis GO:0030162 87 0.024
organic acid metabolic process GO:0006082 103 0.024
negative regulation of microtubule depolymerization GO:0007026 21 0.024
negative regulation of cell communication GO:0010648 223 0.024
regulation of meiosis GO:0040020 3 0.024
positive regulation of nervous system development GO:0051962 69 0.023
developmental maturation GO:0021700 172 0.023
negative regulation of phosphate metabolic process GO:0045936 45 0.023
spindle assembly involved in meiosis GO:0090306 20 0.022
regulation of cellular catabolic process GO:0031329 157 0.022
regulation of gene expression epigenetic GO:0040029 128 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
germarium derived female germ line cyst formation GO:0030727 42 0.022
cell adhesion GO:0007155 136 0.022
mitotic cell cycle embryonic GO:0045448 38 0.021
muscle cell differentiation GO:0042692 103 0.021
regulation of mitosis GO:0007088 56 0.021
Worm
growth GO:0040007 359 0.021
regulation of cytoskeleton organization GO:0051493 89 0.021
Worm
establishment of localization in cell GO:0051649 402 0.021
response to other organism GO:0051707 293 0.021
protein modification process GO:0036211 438 0.020
cellular ketone metabolic process GO:0042180 24 0.020
regulation of catabolic process GO:0009894 170 0.020
dorsal ventral pattern formation GO:0009953 133 0.020
maintenance of protein location in cell GO:0032507 26 0.020
Worm
centrosome duplication GO:0051298 121 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
regulation of organ morphogenesis GO:2000027 78 0.019
sensory organ morphogenesis GO:0090596 260 0.019
nucleoside triphosphate catabolic process GO:0009143 108 0.019
regulation of microtubule cytoskeleton organization GO:0070507 41 0.019
Worm
positive regulation of r7 cell differentiation GO:0045678 7 0.018
stem cell division GO:0017145 69 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
dna replication initiation GO:0006270 6 0.018
nucleoside catabolic process GO:0009164 112 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
Human
single organism catabolic process GO:0044712 228 0.018
regulation of cell cycle process GO:0010564 181 0.018
Human Worm
peptidyl amino acid modification GO:0018193 105 0.018
mitotic spindle midzone assembly GO:0051256 1 0.018
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.018
cell death GO:0008219 279 0.018
response to heat GO:0009408 63 0.018
dna duplex unwinding GO:0032508 16 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
Human
cellular response to lipopolysaccharide GO:0071222 3 0.017
regulation of protein metabolic process GO:0051246 256 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
photoreceptor cell development GO:0042461 96 0.017
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.017
neuroblast division GO:0055057 35 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
positive regulation of response to stimulus GO:0048584 323 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
chemotaxis GO:0006935 249 0.016
regulation of dna metabolic process GO:0051052 34 0.016
regulation of mitotic sister chromatid separation GO:0010965 28 0.016
secretion GO:0046903 109 0.016
sister chromatid cohesion GO:0007062 18 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
regulation of cellular localization GO:0060341 136 0.016
Worm
cell cycle dna replication GO:0044786 23 0.016
negative regulation of phosphorus metabolic process GO:0010563 45 0.016
regulation of cell shape GO:0008360 113 0.016
salivary gland development GO:0007431 162 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
regulation of mitotic spindle elongation GO:0032888 1 0.015
epithelial tube morphogenesis GO:0060562 88 0.015
posttranscriptional gene silencing by rna GO:0035194 45 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
chromatin silencing GO:0006342 76 0.015
cardiovascular system development GO:0072358 82 0.015
aromatic compound catabolic process GO:0019439 166 0.015
programmed cell death GO:0012501 257 0.015
regulation of protein transport GO:0051223 57 0.015
establishment of protein localization GO:0045184 163 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
meiotic cytokinesis GO:0033206 33 0.014
wound healing GO:0042060 75 0.014
regulation of actin filament based process GO:0032970 42 0.014
response to organophosphorus GO:0046683 2 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
regulation of protein localization GO:0032880 76 0.014
Worm
regulation of microtubule depolymerization GO:0031114 24 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.014
compound eye morphogenesis GO:0001745 249 0.014
regulation of dna replication GO:0006275 13 0.013
protein localization GO:0008104 284 0.013
dephosphorylation GO:0016311 51 0.013
negative regulation of chromosome segregation GO:0051985 14 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
regulation of transcription by chromatin organization GO:0034401 3 0.013
cilium organization GO:0044782 41 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.013
neuron projection guidance GO:0097485 241 0.013
negative regulation of signaling GO:0023057 219 0.012
female meiotic division GO:0007143 70 0.012
endomembrane system organization GO:0010256 119 0.012
positive regulation of cell cycle process GO:0090068 28 0.012
camera type eye development GO:0043010 4 0.012
actin filament based process GO:0030029 220 0.012
mitochondrion organization GO:0007005 65 0.012
microtubule anchoring GO:0034453 11 0.012
Worm
regulation of intracellular signal transduction GO:1902531 236 0.012
phagocytosis GO:0006909 215 0.012
regulation of nucleoside metabolic process GO:0009118 50 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
protein localization to organelle GO:0033365 82 0.012
negative regulation of protein depolymerization GO:1901880 23 0.012
immune system process GO:0002376 347 0.012
atp metabolic process GO:0046034 49 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
regulation of phosphorylation GO:0042325 147 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
purine containing compound catabolic process GO:0072523 112 0.011
biological adhesion GO:0022610 138 0.011
neuronal stem cell division GO:0036445 35 0.011
developmental growth GO:0048589 280 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
Human
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.011
positive regulation of neurogenesis GO:0050769 41 0.011
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.011
regulation of behavior GO:0050795 75 0.011
defense response GO:0006952 300 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
protein processing GO:0016485 68 0.011
positive regulation of cell development GO:0010720 61 0.011
embryonic pattern specification GO:0009880 174 0.011
wnt signaling pathway GO:0016055 98 0.010
histone lysine methylation GO:0034968 32 0.010
regionalization GO:0003002 416 0.010
chromatin organization GO:0006325 207 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
body morphogenesis GO:0010171 2 0.010
nucleoside metabolic process GO:0009116 127 0.010
meiotic g2 mi transition GO:0008315 3 0.010
regulation of cellular protein catabolic process GO:1903362 44 0.010
negative regulation of protein maturation GO:1903318 31 0.010

rod disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018