Drosophila melanogaster

113 known processes

Rop (Dmel_CG15811)

Ras opposite

(Aliases: l(3)SH16,Dmel\CG15811,SEC1,CG15811,ras2,l(3)64Ah,rop,rop(Sec1),ROP,cs1)

Rop biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oocyte differentiation GO:0009994 145 0.892
oocyte development GO:0048599 124 0.711
oocyte construction GO:0007308 112 0.584
regionalization GO:0003002 416 0.485
pole plasm oskar mrna localization GO:0045451 46 0.470
pole plasm rna localization GO:0007316 52 0.325
eye development GO:0001654 323 0.325
developmental growth GO:0048589 280 0.321
single organism membrane fusion GO:0044801 42 0.316
cytoskeleton dependent cytokinesis GO:0061640 81 0.294
vesicle fusion GO:0006906 19 0.291
cytokinesis GO:0000910 90 0.275
rna localization GO:0006403 115 0.271
regulation of localization GO:0032879 275 0.266
cytoplasm organization GO:0007028 64 0.227
negative regulation of cell communication GO:0010648 223 0.226
Mouse
establishment of organelle localization GO:0051656 122 0.225
Mouse Rat Worm
pole plasm assembly GO:0007315 61 0.221
establishment of localization in cell GO:0051649 402 0.218
regulation of transport GO:0051049 181 0.218
Mouse Rat Worm
organelle localization GO:0051640 148 0.212
Mouse Rat Worm
germarium derived egg chamber formation GO:0007293 101 0.209
cellular catabolic process GO:0044248 372 0.206
oocyte axis specification GO:0007309 108 0.204
enzyme linked receptor protein signaling pathway GO:0007167 179 0.204
embryo development ending in birth or egg hatching GO:0009792 152 0.201
synaptic vesicle localization GO:0097479 53 0.194
Mouse Rat Worm
vesicle localization GO:0051648 55 0.191
Mouse Rat Worm
homeostatic process GO:0042592 199 0.184
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.179
anterior posterior axis specification GO:0009948 109 0.177
synaptic transmission GO:0007268 288 0.177
single organism intracellular transport GO:1902582 207 0.176
inorganic cation transmembrane transport GO:0098662 61 0.175
developmental maturation GO:0021700 172 0.171
establishment of vesicle localization GO:0051650 51 0.170
Mouse Rat Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.170
tissue migration GO:0090130 155 0.169
response to light stimulus GO:0009416 124 0.160
organelle fission GO:0048285 340 0.153
single organism cellular localization GO:1902580 180 0.152
organelle fusion GO:0048284 46 0.138
cellular macromolecule localization GO:0070727 220 0.136
cell proliferation GO:0008283 299 0.136
regulation of tube size GO:0035150 46 0.136
single organism membrane organization GO:0044802 93 0.135
axis specification GO:0009798 167 0.134
segmentation GO:0035282 207 0.131
positive regulation of cell communication GO:0010647 250 0.130
Worm
regulation of multi organism process GO:0043900 131 0.130
vesicle mediated transport GO:0016192 381 0.128
Mouse Rat Worm
aging GO:0007568 143 0.123
secretion by cell GO:0032940 101 0.115
cell division GO:0051301 248 0.108
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.107
establishment or maintenance of cell polarity GO:0007163 167 0.104
cell maturation GO:0048469 144 0.104
epithelial cell differentiation GO:0030855 322 0.104
negative regulation of response to stimulus GO:0048585 258 0.100
blastoderm segmentation GO:0007350 159 0.099
axon guidance GO:0007411 233 0.099
axon development GO:0061564 297 0.099
Mouse
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.096
embryonic axis specification GO:0000578 107 0.091
maternal determination of anterior posterior axis embryo GO:0008358 74 0.091
exocytosis GO:0006887 28 0.090
Mouse Rat Worm
anterior posterior axis specification embryo GO:0008595 103 0.089
secretion GO:0046903 109 0.088
regulation of developmental growth GO:0048638 174 0.088
monovalent inorganic cation transport GO:0015672 40 0.086
mitotic nuclear division GO:0007067 213 0.084
muscle structure development GO:0061061 224 0.083
cation transmembrane transport GO:0098655 88 0.082
tripartite regional subdivision GO:0007351 103 0.081
single fertilization GO:0007338 24 0.080
appendage morphogenesis GO:0035107 397 0.079
pole plasm mrna localization GO:0019094 49 0.079
compound eye development GO:0048749 307 0.078
oocyte microtubule cytoskeleton organization GO:0016325 35 0.077
nuclear division GO:0000280 332 0.075
negative regulation of cellular metabolic process GO:0031324 382 0.075
cell growth GO:0016049 108 0.074
phosphorylation GO:0016310 294 0.072
membrane fusion GO:0061025 42 0.070
imaginal disc derived appendage development GO:0048737 399 0.070
organic substance transport GO:0071702 257 0.070
cellular protein modification process GO:0006464 438 0.069
fertilization GO:0009566 26 0.068
sensory organ morphogenesis GO:0090596 260 0.067
intracellular mrna localization GO:0008298 66 0.067
molting cycle GO:0042303 56 0.066
post embryonic appendage morphogenesis GO:0035120 385 0.066
eye morphogenesis GO:0048592 260 0.064
positive regulation of signaling GO:0023056 243 0.064
Worm
epidermal growth factor receptor signaling pathway GO:0007173 58 0.063
regulation of multicellular organismal development GO:2000026 414 0.062
multicellular organismal aging GO:0010259 140 0.061
proteolysis GO:0006508 192 0.060
negative regulation of gene expression GO:0010629 387 0.059
determination of adult lifespan GO:0008340 137 0.059
regulation of secretion GO:0051046 44 0.058
Mouse Rat Worm
morphogenesis of an epithelium GO:0002009 276 0.058
regulation of anatomical structure size GO:0090066 163 0.057
response to abiotic stimulus GO:0009628 341 0.057
establishment of synaptic vesicle localization GO:0097480 50 0.057
Mouse Rat Worm
tube development GO:0035295 244 0.057
cellular response to chemical stimulus GO:0070887 199 0.057
response to organic substance GO:0010033 284 0.055
central nervous system development GO:0007417 201 0.054
defense response GO:0006952 300 0.054
rna splicing GO:0008380 83 0.053
regulation of cell cycle process GO:0010564 181 0.053
imaginal disc derived appendage morphogenesis GO:0035114 395 0.053
mitotic spindle organization GO:0007052 220 0.052
growth GO:0040007 359 0.052
open tracheal system development GO:0007424 204 0.051
actin cytoskeleton organization GO:0030036 206 0.050
ovarian follicle cell migration GO:0007297 121 0.050
positive regulation of secretion GO:0051047 22 0.050
Mouse Rat Worm
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.049
response to external biotic stimulus GO:0043207 293 0.049
regulation of actin filament based process GO:0032970 42 0.048
positive regulation of transport GO:0051050 92 0.048
Mouse Rat Worm
detection of abiotic stimulus GO:0009582 66 0.047
embryonic morphogenesis GO:0048598 206 0.046
negative regulation of signal transduction GO:0009968 206 0.046
cell cell junction assembly GO:0007043 38 0.045
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.045
germarium derived female germ line cyst formation GO:0030727 42 0.045
protein complex assembly GO:0006461 200 0.044
Rat
epithelial cell development GO:0002064 274 0.044
regulation of protein metabolic process GO:0051246 256 0.044
macromolecule catabolic process GO:0009057 161 0.043
protein catabolic process GO:0030163 101 0.043
ion transmembrane transport GO:0034220 122 0.042
regulation of cellular protein metabolic process GO:0032268 243 0.042
organic substance catabolic process GO:1901575 308 0.042
tissue morphogenesis GO:0048729 297 0.042
protein modification process GO:0036211 438 0.042
golgi vesicle transport GO:0048193 27 0.042
positive regulation of multicellular organismal process GO:0051240 143 0.042
neuromuscular synaptic transmission GO:0007274 67 0.041
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.041
regulation of synaptic transmission GO:0050804 69 0.040
Mouse Rat Worm
regulation of catabolic process GO:0009894 170 0.040
regulation of mitotic cell cycle GO:0007346 190 0.040
intracellular transport GO:0046907 228 0.039
germ line cyst formation GO:0048134 44 0.039
regulation of cell cycle GO:0051726 291 0.039
respiratory system development GO:0060541 213 0.039
programmed cell death GO:0012501 257 0.039
Mouse
anterior posterior pattern specification GO:0009952 136 0.039
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.038
purine nucleoside triphosphate metabolic process GO:0009144 119 0.037
appendage development GO:0048736 401 0.037
ion transport GO:0006811 145 0.037
cell motility GO:0048870 251 0.037
chromosome segregation GO:0007059 157 0.036
gliogenesis GO:0042063 80 0.036
ovarian follicle cell development GO:0030707 248 0.036
ameboidal type cell migration GO:0001667 151 0.036
cell migration GO:0016477 238 0.036
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.035
molting cycle chitin based cuticle GO:0007591 56 0.035
positive regulation of developmental process GO:0051094 143 0.035
apoptotic process GO:0006915 159 0.035
Mouse
neurotransmitter secretion GO:0007269 35 0.035
modification dependent protein catabolic process GO:0019941 78 0.035
regulation of proteasomal protein catabolic process GO:0061136 39 0.035
regulation of cellular component movement GO:0051270 42 0.034
response to wounding GO:0009611 94 0.034
embryonic pattern specification GO:0009880 174 0.034
meiotic nuclear division GO:0007126 151 0.033
negative regulation of signaling GO:0023057 219 0.033
Mouse
positive regulation of cellular component organization GO:0051130 156 0.033
detection of light stimulus GO:0009583 58 0.032
neuron projection guidance GO:0097485 241 0.032
skeletal muscle organ development GO:0060538 48 0.031
dorsal ventral pattern formation GO:0009953 133 0.031
regulation of response to external stimulus GO:0032101 115 0.031
cellular macromolecule catabolic process GO:0044265 136 0.031
synaptic vesicle recycling GO:0036465 28 0.031
Mouse
metal ion transport GO:0030001 74 0.031
protein localization GO:0008104 284 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
modification dependent macromolecule catabolic process GO:0043632 79 0.030
female germ line cyst formation GO:0048135 42 0.030
cation transport GO:0006812 110 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
columnar cuboidal epithelial cell development GO:0002066 249 0.029
catabolic process GO:0009056 409 0.029
regulation of epithelial cell proliferation GO:0050678 4 0.028
regulation of cellular localization GO:0060341 136 0.028
cellular response to organic substance GO:0071310 132 0.028
negative regulation of protein metabolic process GO:0051248 85 0.027
cuticle development GO:0042335 86 0.027
regulation of reproductive process GO:2000241 54 0.027
glial cell development GO:0021782 27 0.027
nucleus localization GO:0051647 34 0.027
synaptic vesicle transport GO:0048489 50 0.027
Mouse Rat Worm
phototransduction GO:0007602 52 0.027
axonogenesis GO:0007409 290 0.026
Mouse
atp metabolic process GO:0046034 49 0.026
cellular response to heat GO:0034605 24 0.026
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.026
establishment of blood brain barrier GO:0060856 16 0.026
tube morphogenesis GO:0035239 191 0.026
epithelium migration GO:0090132 148 0.026
chitin based cuticle development GO:0040003 49 0.026
cytoskeleton dependent intracellular transport GO:0030705 44 0.025
membrane organization GO:0061024 112 0.025
cell cell junction organization GO:0045216 55 0.025
regulation of dendrite morphogenesis GO:0048814 28 0.025
intracellular protein transport GO:0006886 104 0.025
actin filament based process GO:0030029 220 0.025
positive regulation of secretion by cell GO:1903532 20 0.025
Mouse Rat Worm
erbb signaling pathway GO:0038127 58 0.025
wing disc morphogenesis GO:0007472 344 0.024
localization of cell GO:0051674 257 0.024
lipid modification GO:0030258 24 0.024
cell fate determination GO:0001709 91 0.024
spindle assembly GO:0051225 80 0.024
ubiquitin dependent protein catabolic process GO:0006511 78 0.024
actin filament based movement GO:0030048 26 0.024
mitotic cytokinesis GO:0000281 50 0.024
protein transport GO:0015031 155 0.024
regulation of cell cycle phase transition GO:1901987 130 0.023
digestive system development GO:0055123 149 0.023
organonitrogen compound metabolic process GO:1901564 318 0.023
dephosphorylation GO:0016311 51 0.023
regulation of cell division GO:0051302 72 0.023
regulation of cell differentiation GO:0045595 302 0.023
pronuclear migration GO:0035046 4 0.023
establishment of protein localization GO:0045184 163 0.022
nitrogen compound transport GO:0071705 85 0.022
intracellular signal transduction GO:0035556 300 0.022
death GO:0016265 284 0.022
Mouse
response to biotic stimulus GO:0009607 294 0.022
morphogenesis of follicular epithelium GO:0016333 36 0.021
inorganic ion transmembrane transport GO:0098660 73 0.021
response to starvation GO:0042594 97 0.021
microtubule based transport GO:0010970 42 0.021
protein complex biogenesis GO:0070271 201 0.021
Rat
response to organophosphorus GO:0046683 2 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
purine nucleoside monophosphate metabolic process GO:0009126 50 0.020
protein phosphorylation GO:0006468 169 0.020
response to other organism GO:0051707 293 0.020
autophagy GO:0006914 108 0.020
chemotaxis GO:0006935 249 0.020
neurotransmitter transport GO:0006836 37 0.020
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.020
establishment of nucleus localization GO:0040023 26 0.020
cell death GO:0008219 279 0.019
Mouse
immune system process GO:0002376 347 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.019
regulation of transmembrane transport GO:0034762 27 0.019
regulation of growth GO:0040008 233 0.019
developmental cell growth GO:0048588 52 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
regulation of neuron differentiation GO:0045664 103 0.019
purine containing compound catabolic process GO:0072523 112 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
atp catabolic process GO:0006200 38 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
signal transduction by phosphorylation GO:0023014 107 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
endomembrane system organization GO:0010256 119 0.018
organelle assembly GO:0070925 198 0.018
phagocytosis GO:0006909 215 0.018
nuclear migration GO:0007097 20 0.018
protein processing GO:0016485 68 0.018
protein maturation GO:0051604 71 0.018
forebrain development GO:0030900 2 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
digestive tract morphogenesis GO:0048546 127 0.017
positive regulation of signal transduction GO:0009967 223 0.017
branching involved in open tracheal system development GO:0060446 45 0.017
proteasomal protein catabolic process GO:0010498 59 0.017
actin mediated cell contraction GO:0070252 21 0.017
synaptic vesicle priming GO:0016082 1 0.017
Rat
signal release GO:0023061 49 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
single organism catabolic process GO:0044712 228 0.017
ribonucleoside monophosphate metabolic process GO:0009161 51 0.017
nucleobase containing compound transport GO:0015931 56 0.017
mrna processing GO:0006397 104 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
regulation of molecular function GO:0065009 217 0.017
autophagic vacuole assembly GO:0000045 2 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
epithelial cell migration GO:0010631 148 0.016
regulation of synaptic plasticity GO:0048167 14 0.016
Mouse
negative regulation of cell cycle GO:0045786 116 0.016
defense response to other organism GO:0098542 225 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
larval development GO:0002164 104 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
maintenance of location GO:0051235 73 0.016
cellular protein localization GO:0034613 160 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
macromolecular complex assembly GO:0065003 256 0.016
Rat
cell cycle phase transition GO:0044770 140 0.016
cellular protein complex assembly GO:0043623 71 0.016
Rat
spermatogenesis GO:0007283 200 0.016
wnt signaling pathway GO:0016055 98 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
telencephalon development GO:0021537 2 0.015
actin filament organization GO:0007015 126 0.015
negative regulation of phosphorus metabolic process GO:0010563 45 0.015
pigmentation GO:0043473 75 0.015
chemical homeostasis GO:0048878 92 0.015
compound eye morphogenesis GO:0001745 249 0.015
action potential GO:0001508 13 0.015
cellular protein catabolic process GO:0044257 83 0.015
regulation of programmed cell death GO:0043067 152 0.015
Mouse
response to oxygen containing compound GO:1901700 200 0.015
neuromuscular junction development GO:0007528 149 0.015
epidermis development GO:0008544 65 0.015
neurological system process GO:0050877 358 0.015
neuronal action potential GO:0019228 10 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.014
endocytosis GO:0006897 310 0.014
Mouse
regulation of neuron projection development GO:0010975 69 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
regulation of rna splicing GO:0043484 69 0.014
nucleoside monophosphate metabolic process GO:0009123 52 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
potassium ion transport GO:0006813 20 0.014
neuron recognition GO:0008038 101 0.014
regulation of wnt signaling pathway GO:0030111 68 0.014
kidney development GO:0001822 3 0.013
oxoacid metabolic process GO:0043436 103 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
monocarboxylic acid transport GO:0015718 3 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
Rat
developmental pigmentation GO:0048066 68 0.013
regulation of phosphorylation GO:0042325 147 0.013
meiotic cell cycle process GO:1903046 132 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
mapk cascade GO:0000165 107 0.013
epithelial cell proliferation GO:0050673 15 0.013
regulation of cellular component size GO:0032535 98 0.013
border follicle cell migration GO:0007298 113 0.013
circulatory system process GO:0003013 37 0.013
protein targeting GO:0006605 64 0.013
positive regulation of cell cycle GO:0045787 43 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
oocyte dorsal ventral axis specification GO:0007310 34 0.013
regulation of blood circulation GO:1903522 21 0.013
anatomical structure homeostasis GO:0060249 97 0.013
small molecule metabolic process GO:0044281 305 0.013
single organism biosynthetic process GO:0044711 206 0.013
regulation of mrna metabolic process GO:1903311 72 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
regulation of response to stress GO:0080134 200 0.012
regulation of oocyte development GO:0060281 27 0.012
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.012
skeletal muscle fiber development GO:0048741 3 0.012
regulation of pole plasm oskar mrna localization GO:0007317 27 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
regulation of catalytic activity GO:0050790 185 0.012
negative regulation of organelle organization GO:0010639 56 0.012
meiotic cell cycle GO:0051321 171 0.012
regulation of nervous system development GO:0051960 248 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
purine nucleoside monophosphate catabolic process GO:0009128 38 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
regulation of cell death GO:0010941 173 0.012
Mouse
regulation of cell projection organization GO:0031344 92 0.012
meiotic chromosome segregation GO:0045132 59 0.012
spinal cord development GO:0021510 1 0.012
lipid metabolic process GO:0006629 121 0.011
ribonucleoside monophosphate catabolic process GO:0009158 39 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
regulation of neurogenesis GO:0050767 158 0.011
detection of stimulus GO:0051606 156 0.011
cell junction organization GO:0034330 57 0.011
transmembrane transport GO:0055085 139 0.011
dendrite morphogenesis GO:0048813 199 0.011
regulation of necrotic cell death GO:0010939 1 0.011
oxidation reduction process GO:0055114 123 0.011
apical junction assembly GO:0043297 32 0.011
regulation of system process GO:0044057 36 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
camera type eye development GO:0043010 4 0.011
positive regulation of gene expression GO:0010628 290 0.011
positive regulation of growth GO:0045927 75 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
mrna metabolic process GO:0016071 124 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
positive regulation of cell proliferation GO:0008284 47 0.011
purine nucleoside biosynthetic process GO:0042451 3 0.011
striated muscle cell differentiation GO:0051146 90 0.011
regulation of protein transport GO:0051223 57 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
regulation of immune system process GO:0002682 176 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
cell recognition GO:0008037 102 0.010
regulation of cellular response to growth factor stimulus GO:0090287 13 0.010
endoplasmic reticulum organization GO:0007029 13 0.010
necrotic cell death GO:0070265 1 0.010
regulation of organelle organization GO:0033043 196 0.010
regulation of membrane potential GO:0042391 35 0.010
axon cargo transport GO:0008088 29 0.010

Rop disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.065
musculoskeletal system disease DOID:17 0 0.021