Drosophila melanogaster

15 known processes

pfk (Dmel_CG15812)

piefke

(Aliases: CG15812,Dmel\CG15812)

pfk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myoblast fusion GO:0007520 43 0.991
syncytium formation by plasma membrane fusion GO:0000768 43 0.970
syncytium formation GO:0006949 43 0.968
myotube differentiation GO:0014902 46 0.914
striated muscle cell differentiation GO:0051146 90 0.834
muscle structure development GO:0061061 224 0.689
muscle cell differentiation GO:0042692 103 0.505
somatic muscle development GO:0007525 66 0.187
muscle attachment GO:0016203 36 0.174
lateral inhibition GO:0046331 206 0.144
skeletal muscle organ development GO:0060538 48 0.101
imaginal disc derived wing morphogenesis GO:0007476 337 0.084
defense response GO:0006952 300 0.084
muscle organ development GO:0007517 127 0.076
cell cell signaling involved in cell fate commitment GO:0045168 210 0.072
imaginal disc derived appendage morphogenesis GO:0035114 395 0.067
wing disc morphogenesis GO:0007472 344 0.066
eye development GO:0001654 323 0.061
actin filament based process GO:0030029 220 0.054
negative regulation of gene expression GO:0010629 387 0.053
actin filament organization GO:0007015 126 0.052
positive regulation of macromolecule metabolic process GO:0010604 405 0.051
appendage development GO:0048736 401 0.050
immune system process GO:0002376 347 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.048
post embryonic appendage morphogenesis GO:0035120 385 0.048
response to monosaccharide GO:0034284 4 0.047
compound eye morphogenesis GO:0001745 249 0.046
immune response GO:0006955 246 0.046
imaginal disc derived appendage development GO:0048737 399 0.045
defense response to bacterium GO:0042742 178 0.045
response to external biotic stimulus GO:0043207 293 0.042
positive regulation of response to stimulus GO:0048584 323 0.040
appendage morphogenesis GO:0035107 397 0.040
regulation of immune system process GO:0002682 176 0.040
larval visceral muscle development GO:0007523 9 0.039
cellular protein modification process GO:0006464 438 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.038
nicotinamide nucleotide metabolic process GO:0046496 2 0.037
nucleotide metabolic process GO:0009117 161 0.037
protein modification process GO:0036211 438 0.037
vesicle mediated transport GO:0016192 381 0.036
regulation of myoblast fusion GO:1901739 6 0.036
dna packaging GO:0006323 91 0.036
embryonic development via the syncytial blastoderm GO:0001700 148 0.034
sensory organ morphogenesis GO:0090596 260 0.034
regionalization GO:0003002 416 0.034
nucleobase containing compound catabolic process GO:0034655 165 0.033
nad metabolic process GO:0019674 1 0.033
male gamete generation GO:0048232 201 0.033
cellular component assembly involved in morphogenesis GO:0010927 151 0.032
positive regulation of biosynthetic process GO:0009891 316 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
purine nucleoside metabolic process GO:0042278 127 0.032
cellular catabolic process GO:0044248 372 0.032
negative regulation of cellular biosynthetic process GO:0031327 277 0.032
response to biotic stimulus GO:0009607 294 0.032
response to other organism GO:0051707 293 0.031
dendrite development GO:0016358 204 0.031
endocytosis GO:0006897 310 0.031
negative regulation of biosynthetic process GO:0009890 277 0.031
posttranscriptional regulation of gene expression GO:0010608 145 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.030
cell death GO:0008219 279 0.030
embryonic pattern specification GO:0009880 174 0.030
positive regulation of nucleic acid templated transcription GO:1903508 266 0.029
negative regulation of nucleic acid templated transcription GO:1903507 240 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
actin cytoskeleton organization GO:0030036 206 0.029
response to nutrient levels GO:0031667 114 0.029
protein localization GO:0008104 284 0.028
macromolecular complex assembly GO:0065003 256 0.028
purine ribonucleoside metabolic process GO:0046128 127 0.028
cuticle development GO:0042335 86 0.028
organophosphate metabolic process GO:0019637 195 0.028
cellular macromolecular complex assembly GO:0034622 153 0.028
heterocycle catabolic process GO:0046700 166 0.027
negative regulation of response to stimulus GO:0048585 258 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.027
oxidoreduction coenzyme metabolic process GO:0006733 2 0.027
ovarian follicle cell development GO:0030707 248 0.027
regulation of notch signaling pathway GO:0008593 100 0.027
defense response to other organism GO:0098542 225 0.026
columnar cuboidal epithelial cell development GO:0002066 249 0.026
regulation of cell shape GO:0008360 113 0.026
negative regulation of rna biosynthetic process GO:1902679 240 0.025
response to glucose GO:0009749 2 0.025
organic substance catabolic process GO:1901575 308 0.025
small molecule metabolic process GO:0044281 305 0.025
body morphogenesis GO:0010171 2 0.025
regulation of mitotic cell cycle phase transition GO:1901990 130 0.024
catabolic process GO:0009056 409 0.024
compound eye development GO:0048749 307 0.024
positive regulation of gene expression GO:0010628 290 0.024
gene silencing GO:0016458 138 0.024
neuron projection guidance GO:0097485 241 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.023
single organism catabolic process GO:0044712 228 0.023
protein complex biogenesis GO:0070271 201 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
organelle assembly GO:0070925 198 0.023
forebrain development GO:0030900 2 0.023
nuclear division GO:0000280 332 0.022
regulation of anatomical structure size GO:0090066 163 0.022
positive regulation of transcription dna templated GO:0045893 266 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
eggshell formation GO:0030703 105 0.022
chromosome organization GO:0051276 360 0.022
gland morphogenesis GO:0022612 145 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.022
growth GO:0040007 359 0.022
regulation of cell differentiation GO:0045595 302 0.022
regulation of syncytium formation by plasma membrane fusion GO:0060142 6 0.022
intracellular signal transduction GO:0035556 300 0.021
regulation of cellular component size GO:0032535 98 0.021
eye morphogenesis GO:0048592 260 0.021
integrin mediated signaling pathway GO:0007229 3 0.021
phagocytosis GO:0006909 215 0.021
guanosine containing compound catabolic process GO:1901069 74 0.021
regulation of catalytic activity GO:0050790 185 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
aromatic compound catabolic process GO:0019439 166 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.021
regulation of cell cycle GO:0051726 291 0.021
response to bacterium GO:0009617 198 0.020
purine nucleoside triphosphate metabolic process GO:0009144 119 0.020
myotube cell development GO:0014904 3 0.020
nucleoside triphosphate metabolic process GO:0009141 120 0.020
regulation of phosphorylation GO:0042325 147 0.020
organic acid metabolic process GO:0006082 103 0.020
phosphorylation GO:0016310 294 0.020
organelle fission GO:0048285 340 0.020
positive regulation of cellular protein metabolic process GO:0032270 118 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
negative regulation of signal transduction GO:0009968 206 0.019
response to abiotic stimulus GO:0009628 341 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
segmentation GO:0035282 207 0.019
antimicrobial humoral response GO:0019730 99 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
response to hexose GO:0009746 3 0.019
response to heat GO:0009408 63 0.019
rna processing GO:0006396 147 0.019
humoral immune response GO:0006959 117 0.019
response to organophosphorus GO:0046683 2 0.019
regulation of translation GO:0006417 56 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
rho protein signal transduction GO:0007266 14 0.019
dorsal appendage formation GO:0046843 47 0.018
positive regulation of cellular component organization GO:0051130 156 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
axonogenesis GO:0007409 290 0.018
dendrite morphogenesis GO:0048813 199 0.018
spermatogenesis GO:0007283 200 0.018
chorion containing eggshell formation GO:0007304 105 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
cell cycle phase transition GO:0044770 140 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
centrosome organization GO:0051297 163 0.018
regulation of gene expression epigenetic GO:0040029 128 0.018
regulation of catabolic process GO:0009894 170 0.018
regulation of molecular function GO:0065009 217 0.018
negative regulation of rna metabolic process GO:0051253 251 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
cell fate determination GO:0001709 91 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
negative regulation of signaling GO:0023057 219 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
regulation of organelle organization GO:0033043 196 0.017
nucleoside metabolic process GO:0009116 127 0.017
translation GO:0006412 69 0.017
connective tissue development GO:0061448 3 0.017
purine containing compound metabolic process GO:0072521 155 0.017
mitotic nuclear division GO:0007067 213 0.017
response to organic substance GO:0010033 284 0.017
striated muscle cell development GO:0055002 50 0.017
multi organism reproductive behavior GO:0044705 121 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
ras protein signal transduction GO:0007265 88 0.017
wing disc pattern formation GO:0035222 66 0.017
membrane organization GO:0061024 112 0.017
chemotaxis GO:0006935 249 0.017
eggshell chorion assembly GO:0007306 66 0.016
notch signaling pathway GO:0007219 120 0.016
axon development GO:0061564 297 0.016
positive regulation of mapk cascade GO:0043410 63 0.016
lipid localization GO:0010876 54 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
endomembrane system organization GO:0010256 119 0.016
synapse organization GO:0050808 196 0.016
respiratory system development GO:0060541 213 0.016
epithelial cell development GO:0002064 274 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
oxoacid metabolic process GO:0043436 103 0.016
open tracheal system development GO:0007424 204 0.016
regulation of protein metabolic process GO:0051246 256 0.016
positive regulation of signal transduction GO:0009967 223 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
visceral muscle development GO:0007522 14 0.016
sterol homeostasis GO:0055092 4 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.015
larval somatic muscle development GO:0007526 19 0.015
developmental growth GO:0048589 280 0.015
response to nitrogen compound GO:1901698 90 0.015
regulation of transport GO:0051049 181 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
mesenchymal cell differentiation GO:0048762 1 0.015
rna splicing GO:0008380 83 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
locomotory behavior GO:0007626 176 0.015
homeostatic process GO:0042592 199 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
positive regulation of lipid metabolic process GO:0045834 4 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
nucleoside catabolic process GO:0009164 112 0.014
regulation of nucleotide catabolic process GO:0030811 48 0.014
meiotic cell cycle GO:0051321 171 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
innate immune response GO:0045087 144 0.014
regulation of localization GO:0032879 275 0.014
chromatin silencing GO:0006342 76 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
synapse assembly GO:0007416 143 0.014
regulation of cell cycle process GO:0010564 181 0.014
gtp catabolic process GO:0006184 72 0.014
positive regulation of immune system process GO:0002684 68 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
anatomical structure homeostasis GO:0060249 97 0.014
axon guidance GO:0007411 233 0.013
camera type eye development GO:0043010 4 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
actin filament polymerization GO:0030041 27 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
organophosphate catabolic process GO:0046434 112 0.013
gtp metabolic process GO:0046039 72 0.013
regulation of actin polymerization or depolymerization GO:0008064 27 0.013
salivary gland morphogenesis GO:0007435 145 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
regulation of ras gtpase activity GO:0032318 38 0.013
gland development GO:0048732 191 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
cell motility GO:0048870 251 0.013
response to lipopolysaccharide GO:0032496 4 0.013
protein phosphorylation GO:0006468 169 0.013
macromolecule catabolic process GO:0009057 161 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
single organism membrane fusion GO:0044801 42 0.013
lipid storage GO:0019915 38 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
positive regulation of molecular function GO:0044093 136 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
negative regulation of cell communication GO:0010648 223 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
chromatin organization GO:0006325 207 0.012
positive regulation of developmental process GO:0051094 143 0.012
organic substance transport GO:0071702 257 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
substrate adhesion dependent cell spreading GO:0034446 2 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of response to stress GO:0080134 200 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
negative regulation of translation GO:0017148 28 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
positive regulation of signaling GO:0023056 243 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
dna conformation change GO:0071103 105 0.012
biological adhesion GO:0022610 138 0.012
regulation of growth GO:0040008 233 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
regulation of rna splicing GO:0043484 69 0.012
activation of ras gtpase activity GO:0032856 6 0.012
regulation of mrna processing GO:0050684 71 0.012
cell aging GO:0007569 2 0.012
single organism behavior GO:0044708 391 0.012
regulation of programmed cell death GO:0043067 152 0.012
skeletal muscle fiber development GO:0048741 3 0.012
single organism intracellular transport GO:1902582 207 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
regulation of cell fate specification GO:0042659 27 0.012
programmed cell death GO:0012501 257 0.012
imaginal disc pattern formation GO:0007447 91 0.012
leg disc morphogenesis GO:0007478 80 0.011
chromatin assembly GO:0031497 48 0.011
response to mercury ion GO:0046689 3 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.011
anterior posterior pattern specification GO:0009952 136 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
chaeta development GO:0022416 97 0.011
cell migration GO:0016477 238 0.011
blastoderm segmentation GO:0007350 159 0.011
histone modification GO:0016570 106 0.011
single organism membrane organization GO:0044802 93 0.011
protein heterooligomerization GO:0051291 4 0.011
determination of muscle attachment site GO:0016204 7 0.011
death GO:0016265 284 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
regulation of hydrolase activity GO:0051336 97 0.011
anion homeostasis GO:0055081 3 0.011
establishment of protein localization GO:0045184 163 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
carbohydrate metabolic process GO:0005975 82 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
cellular macromolecule localization GO:0070727 220 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
cuticle pattern formation GO:0035017 27 0.011
positive regulation of gtp catabolic process GO:0033126 43 0.011
spermatid differentiation GO:0048515 114 0.011
leg disc development GO:0035218 92 0.011
actin polymerization or depolymerization GO:0008154 31 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.011
regulation of striated muscle tissue development GO:0016202 5 0.010
positive regulation of cell communication GO:0010647 250 0.010
mrna processing GO:0006397 104 0.010
nucleotide catabolic process GO:0009166 109 0.010
chromosome condensation GO:0030261 41 0.010
positive regulation of cell motility GO:2000147 3 0.010
myofibril assembly GO:0030239 36 0.010
positive regulation of cell migration GO:0030335 2 0.010
lamellipodium assembly GO:0030032 21 0.010
mapk cascade GO:0000165 107 0.010
cell adhesion GO:0007155 136 0.010
regulation of cell size GO:0008361 63 0.010
response to starvation GO:0042594 97 0.010

pfk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
nervous system disease DOID:863 0 0.011
cardiovascular system disease DOID:1287 0 0.010
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010