Drosophila melanogaster

57 known processes

tra (Dmel_CG16724)

transformer

(Aliases: TRA,Dmtra,Dmel\CG16724,Tra,CG16724)

tra biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
male courtship behavior GO:0008049 63 0.987
male courtship behavior veined wing extension GO:0048065 22 0.934
courtship behavior GO:0007619 68 0.906
gene silencing GO:0016458 138 0.851
regulation of gene expression epigenetic GO:0040029 128 0.844
male courtship behavior veined wing generated song production GO:0045433 20 0.790
male mating behavior GO:0060179 70 0.731
negative regulation of gene expression GO:0010629 387 0.706
mating GO:0007618 120 0.687
male courtship behavior veined wing vibration GO:0016545 21 0.684
negative regulation of cellular metabolic process GO:0031324 382 0.547
mating behavior GO:0007617 106 0.517
single organism behavior GO:0044708 391 0.508
negative regulation of signal transduction GO:0009968 206 0.467
gene silencing by rna GO:0031047 57 0.466
negative regulation of signaling GO:0023057 219 0.448
rna interference GO:0016246 27 0.442
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.423
posttranscriptional gene silencing by rna GO:0035194 45 0.416
multi organism reproductive behavior GO:0044705 121 0.411
negative regulation of response to stimulus GO:0048585 258 0.368
axonogenesis GO:0007409 290 0.362
locomotory behavior GO:0007626 176 0.351
negative regulation of cellular biosynthetic process GO:0031327 277 0.309
establishment of localization in cell GO:0051649 402 0.299
mrna metabolic process GO:0016071 124 0.298
ribonucleotide metabolic process GO:0009259 145 0.294
g protein coupled receptor signaling pathway GO:0007186 136 0.291
adult behavior GO:0030534 137 0.282
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.280
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.276
negative regulation of transcription dna templated GO:0045892 237 0.272
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.270
multi organism behavior GO:0051705 175 0.256
kidney development GO:0001822 3 0.247
posttranscriptional regulation of gene expression GO:0010608 145 0.244
sensory perception GO:0007600 196 0.239
negative regulation of nucleic acid templated transcription GO:1903507 240 0.229
cell growth GO:0016049 108 0.228
negative regulation of cell communication GO:0010648 223 0.221
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.196
organic substance catabolic process GO:1901575 308 0.190
dendrite development GO:0016358 204 0.183
neurological system process GO:0050877 358 0.182
growth GO:0040007 359 0.172
regulation of catalytic activity GO:0050790 185 0.171
developmental growth GO:0048589 280 0.169
response to oxygen containing compound GO:1901700 200 0.162
nucleobase containing small molecule metabolic process GO:0055086 174 0.161
axon development GO:0061564 297 0.160
ribose phosphate metabolic process GO:0019693 145 0.153
dendrite morphogenesis GO:0048813 199 0.136
vesicle mediated transport GO:0016192 381 0.134
posttranscriptional gene silencing GO:0016441 46 0.130
positive regulation of transcription dna templated GO:0045893 266 0.126
negative regulation of biosynthetic process GO:0009890 277 0.125
mrna processing GO:0006397 104 0.124
regulation of localization GO:0032879 275 0.115
regulation of cellular component biogenesis GO:0044087 201 0.113
nephron tubule morphogenesis GO:0072078 3 0.104
carbohydrate derivative metabolic process GO:1901135 217 0.103
sex determination GO:0007530 18 0.100
response to light stimulus GO:0009416 124 0.100
localization of cell GO:0051674 257 0.098
regulation of nervous system development GO:0051960 248 0.097
cellular macromolecule catabolic process GO:0044265 136 0.096
nucleobase containing compound catabolic process GO:0034655 165 0.095
protein localization GO:0008104 284 0.093
cellular response to radiation GO:0071478 52 0.088
dna templated transcription initiation GO:0006352 25 0.086
organelle localization GO:0051640 148 0.081
negative regulation of rna biosynthetic process GO:1902679 240 0.080
multicellular organismal reproductive behavior GO:0033057 110 0.080
small molecule metabolic process GO:0044281 305 0.078
positive regulation of biosynthetic process GO:0009891 316 0.077
actin cytoskeleton organization GO:0030036 206 0.073
male gamete generation GO:0048232 201 0.071
proteolysis GO:0006508 192 0.070
regulation of molecular function GO:0065009 217 0.069
multi multicellular organism process GO:0044706 123 0.068
genital disc development GO:0035215 44 0.068
response to radiation GO:0009314 155 0.068
positive regulation of rna metabolic process GO:0051254 271 0.067
negative regulation of rna metabolic process GO:0051253 251 0.066
purine containing compound metabolic process GO:0072521 155 0.066
cell motility GO:0048870 251 0.065
actin filament based process GO:0030029 220 0.065
regulation of growth GO:0040008 233 0.065
regulation of cell development GO:0060284 215 0.065
chromosome organization GO:0051276 360 0.065
single organism biosynthetic process GO:0044711 206 0.065
reproductive behavior GO:0019098 122 0.064
cellular catabolic process GO:0044248 372 0.064
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.063
organophosphate metabolic process GO:0019637 195 0.063
response to organic substance GO:0010033 284 0.062
germarium derived egg chamber formation GO:0007293 101 0.061
positive regulation of cellular component biogenesis GO:0044089 80 0.059
cell death GO:0008219 279 0.057
protein complex assembly GO:0006461 200 0.057
nucleoside phosphate metabolic process GO:0006753 162 0.056
microtubule based transport GO:0010970 42 0.055
regulation of mrna metabolic process GO:1903311 72 0.055
detection of abiotic stimulus GO:0009582 66 0.055
nephron epithelium morphogenesis GO:0072088 3 0.054
positive regulation of cellular biosynthetic process GO:0031328 316 0.053
positive regulation of cellular component organization GO:0051130 156 0.053
sensory organ morphogenesis GO:0090596 260 0.052
regulation of cell death GO:0010941 173 0.051
positive regulation of cellular catabolic process GO:0031331 95 0.051
regulation of cell differentiation GO:0045595 302 0.050
regulation of anatomical structure size GO:0090066 163 0.050
secondary metabolic process GO:0019748 75 0.050
positive regulation of macromolecule metabolic process GO:0010604 405 0.050
death GO:0016265 284 0.050
covalent chromatin modification GO:0016569 106 0.048
endocytosis GO:0006897 310 0.047
programmed cell death GO:0012501 257 0.047
regulation of meiosis GO:0040020 3 0.046
negative regulation of cell differentiation GO:0045596 143 0.045
purine nucleotide metabolic process GO:0006163 146 0.045
positive regulation of rna biosynthetic process GO:1902680 266 0.045
regulation of programmed cell death GO:0043067 152 0.045
nucleotide metabolic process GO:0009117 161 0.045
negative regulation of phosphate metabolic process GO:0045936 45 0.044
regulation of neuron differentiation GO:0045664 103 0.043
germ cell migration GO:0008354 43 0.043
aromatic compound catabolic process GO:0019439 166 0.042
regulation of transport GO:0051049 181 0.042
central nervous system development GO:0007417 201 0.041
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.041
regulation of response to stress GO:0080134 200 0.041
meiotic cell cycle process GO:1903046 132 0.041
molting cycle chitin based cuticle GO:0007591 56 0.040
organic substance transport GO:0071702 257 0.040
nephron morphogenesis GO:0072028 3 0.040
response to abiotic stimulus GO:0009628 341 0.039
regulation of developmental growth GO:0048638 174 0.039
apoptotic process GO:0006915 159 0.038
macromolecular complex assembly GO:0065003 256 0.038
positive regulation of gene expression GO:0010628 290 0.038
detection of external stimulus GO:0009581 66 0.037
spindle organization GO:0007051 253 0.037
positive regulation of developmental process GO:0051094 143 0.037
neuronal stem cell division GO:0036445 35 0.037
axon guidance GO:0007411 233 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.036
regulation of cellular component size GO:0032535 98 0.036
cell proliferation GO:0008283 299 0.035
negative regulation of apoptotic process GO:0043066 63 0.035
positive regulation of multicellular organismal process GO:0051240 143 0.034
eye morphogenesis GO:0048592 260 0.034
cellular response to extracellular stimulus GO:0031668 64 0.034
cellular macromolecular complex assembly GO:0034622 153 0.034
heterocycle catabolic process GO:0046700 166 0.032
cellular nitrogen compound catabolic process GO:0044270 165 0.032
negative regulation of gene expression epigenetic GO:0045814 77 0.032
regulation of cell cycle GO:0051726 291 0.032
chemotaxis GO:0006935 249 0.032
imaginal disc derived appendage development GO:0048737 399 0.031
lipid biosynthetic process GO:0008610 46 0.031
negative regulation of neuron death GO:1901215 18 0.031
single organism cell adhesion GO:0098602 47 0.031
kidney epithelium development GO:0072073 3 0.031
sarcomere organization GO:0045214 26 0.030
regulation of vesicle mediated transport GO:0060627 59 0.029
positive regulation of nervous system development GO:0051962 69 0.029
mushroom body development GO:0016319 70 0.029
regulation of organelle organization GO:0033043 196 0.029
organic cyclic compound catabolic process GO:1901361 168 0.029
regulation of actin cytoskeleton organization GO:0032956 42 0.028
cell junction assembly GO:0034329 42 0.028
protein modification process GO:0036211 438 0.028
regulation of phosphate metabolic process GO:0019220 210 0.028
purine ribonucleoside metabolic process GO:0046128 127 0.028
cell cell junction organization GO:0045216 55 0.028
alternative mrna splicing via spliceosome GO:0000380 60 0.027
negative regulation of developmental process GO:0051093 201 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
sensory perception of mechanical stimulus GO:0050954 72 0.026
positive regulation of signal transduction GO:0009967 223 0.026
nucleoside metabolic process GO:0009116 127 0.026
ovarian fusome organization GO:0030723 11 0.025
protein transport GO:0015031 155 0.025
regulation of cell projection organization GO:0031344 92 0.025
regulation of mrna processing GO:0050684 71 0.025
embryonic hemopoiesis GO:0035162 26 0.024
chromatin silencing GO:0006342 76 0.024
transcription from rna polymerase ii promoter GO:0006366 368 0.024
rna splicing via transesterification reactions GO:0000375 73 0.024
imaginal disc fusion GO:0046528 19 0.024
actomyosin structure organization GO:0031032 56 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.024
reproductive structure development GO:0048608 74 0.024
neuron projection guidance GO:0097485 241 0.024
regulation of cellular localization GO:0060341 136 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.023
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.023
regulation of multicellular organismal development GO:2000026 414 0.022
macromolecule catabolic process GO:0009057 161 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
oocyte development GO:0048599 124 0.022
spermatogenesis GO:0007283 200 0.022
transposition GO:0032196 13 0.021
positive regulation of signaling GO:0023056 243 0.021
kidney morphogenesis GO:0060993 3 0.021
regulation of autophagy GO:0010506 62 0.021
positive regulation of molecular function GO:0044093 136 0.021
positive regulation of cell communication GO:0010647 250 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
reproductive system development GO:0061458 74 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
synapse assembly GO:0007416 143 0.020
neuromuscular junction development GO:0007528 149 0.020
adult locomotory behavior GO:0008344 76 0.020
eye antennal disc development GO:0035214 60 0.020
single organism intracellular transport GO:1902582 207 0.020
developmental growth involved in morphogenesis GO:0060560 65 0.020
multicellular organism growth GO:0035264 46 0.020
organonitrogen compound metabolic process GO:1901564 318 0.020
immune system process GO:0002376 347 0.020
cellular protein modification process GO:0006464 438 0.020
response to temperature stimulus GO:0009266 106 0.020
regulation of cellular response to oxidative stress GO:1900407 4 0.019
histone acetylation GO:0016573 38 0.019
morphogenesis of follicular epithelium GO:0016333 36 0.019
single organismal cell cell adhesion GO:0016337 45 0.019
secondary metabolite biosynthetic process GO:0044550 24 0.019
regulation of nucleotide metabolic process GO:0006140 62 0.019
response to x ray GO:0010165 8 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
rna splicing GO:0008380 83 0.018
mrna catabolic process GO:0006402 33 0.018
anterograde axon cargo transport GO:0008089 6 0.018
histone modification GO:0016570 106 0.018
protein complex biogenesis GO:0070271 201 0.018
establishment of protein localization GO:0045184 163 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.018
defense response GO:0006952 300 0.018
catabolic process GO:0009056 409 0.017
positive regulation of developmental growth GO:0048639 62 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
lipid homeostasis GO:0055088 33 0.017
mating behavior sex discrimination GO:0048047 7 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.016
peptidyl lysine acetylation GO:0018394 39 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.016
regulation of protein localization GO:0032880 76 0.016
regulation of hydrolase activity GO:0051336 97 0.016
female germ line cyst formation GO:0048135 42 0.016
cell division GO:0051301 248 0.016
male courtship behavior tapping to detect pheromone GO:0016544 1 0.016
glycosyl compound catabolic process GO:1901658 112 0.016
signal release GO:0023061 49 0.016
dna metabolic process GO:0006259 227 0.016
organ growth GO:0035265 56 0.016
salivary gland morphogenesis GO:0007435 145 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
regulation of purine nucleotide metabolic process GO:1900542 62 0.015
cortical actin cytoskeleton organization GO:0030866 24 0.015
negative regulation of response to oxidative stress GO:1902883 1 0.015
detection of stimulus GO:0051606 156 0.015
lipid storage GO:0019915 38 0.015
regulation of cellular response to stress GO:0080135 89 0.015
intracellular signal transduction GO:0035556 300 0.015
photoreceptor cell development GO:0042461 96 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
secretion by cell GO:0032940 101 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
sex differentiation GO:0007548 81 0.015
rna processing GO:0006396 147 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
histolysis GO:0007559 102 0.014
regulation of neuron projection development GO:0010975 69 0.014
spinal cord development GO:0021510 1 0.014
regulation of response to external stimulus GO:0032101 115 0.014
internal peptidyl lysine acetylation GO:0018393 38 0.014
rna catabolic process GO:0006401 37 0.014
lipid localization GO:0010876 54 0.014
regulation of synapse organization GO:0050807 110 0.014
regulation of synapse assembly GO:0051963 94 0.014
response to oxidative stress GO:0006979 86 0.014
nucleotide catabolic process GO:0009166 109 0.014
positive regulation of catabolic process GO:0009896 105 0.014
regulation of catabolic process GO:0009894 170 0.014
negative regulation of cellular response to oxidative stress GO:1900408 1 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.013
apoptotic signaling pathway GO:0097190 27 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.013
germ line stem cell maintenance GO:0030718 50 0.013
epithelial tube morphogenesis GO:0060562 88 0.013
nephron development GO:0072006 3 0.013
stem cell differentiation GO:0048863 117 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
negative regulation of cell death GO:0060548 81 0.013
camera type eye development GO:0043010 4 0.013
spermatocyte division GO:0048137 13 0.013
muscle system process GO:0003012 21 0.013
cellular ketone metabolic process GO:0042180 24 0.013
phagocytosis GO:0006909 215 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
positive regulation of cell differentiation GO:0045597 64 0.013
synaptic vesicle transport GO:0048489 50 0.012
vesicle localization GO:0051648 55 0.012
taxis GO:0042330 304 0.012
positive regulation of transport GO:0051050 92 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
cell adhesion GO:0007155 136 0.012
receptor mediated endocytosis GO:0006898 21 0.012
melanization defense response GO:0035006 45 0.012
chemical homeostasis GO:0048878 92 0.012
sister chromatid segregation GO:0000819 92 0.012
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
regulation of gene silencing GO:0060968 63 0.012
epithelial cell differentiation GO:0030855 322 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.011
regulation of phosphatase activity GO:0010921 3 0.011
wnt signaling pathway GO:0016055 98 0.011
imaginal disc derived female genitalia development GO:0007486 6 0.011
negative regulation of neuron apoptotic process GO:0043524 14 0.011
cell migration GO:0016477 238 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
protein localization to peroxisome GO:0072662 2 0.011
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.011
positive regulation of cell migration GO:0030335 2 0.011
appendage development GO:0048736 401 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of stem cell differentiation GO:2000736 14 0.011
gliogenesis GO:0042063 80 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
regulation of meiotic cell cycle GO:0051445 9 0.011
positive regulation of organelle organization GO:0010638 65 0.011
negative regulation of meiotic cell cycle GO:0051447 2 0.011
regulation of cytoskeleton organization GO:0051493 89 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
cytoskeleton dependent intracellular transport GO:0030705 44 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
negative regulation of cell proliferation GO:0008285 69 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
regulation of endocytosis GO:0030100 37 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
exocrine system development GO:0035272 162 0.010

tra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.015