Drosophila melanogaster

95 known processes

slp1 (Dmel_CG16738)

sloppy paired 1

(Aliases: CG16738,Dmel\CG16738,slp-2,Slp,FoxG,slp,slp-1,Slp1,Slp-1,FD6,SLP1,l(2)05965,Dmslp1,sko1)

slp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
head segmentation GO:0035287 13 0.998
negative regulation of transcription dna templated GO:0045892 237 0.992
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.992
transcription from rna polymerase ii promoter GO:0006366 368 0.985
tube development GO:0035295 244 0.984
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.982
mesoderm development GO:0007498 78 0.977
Fly
heart morphogenesis GO:0003007 32 0.976
renal tubule development GO:0061326 64 0.972
Fly
digestive system development GO:0055123 149 0.971
Fly
segmentation GO:0035282 207 0.962
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.960
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.955
tissue morphogenesis GO:0048729 297 0.952
Fly
head development GO:0060322 135 0.952
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.950
Worm Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.948
negative regulation of gene expression GO:0010629 387 0.947
stem cell differentiation GO:0048863 117 0.938
malpighian tubule morphogenesis GO:0007443 44 0.936
Fly
heart development GO:0007507 82 0.934
positive regulation of gene expression GO:0010628 290 0.931
Worm Fly
regionalization GO:0003002 416 0.929
negative regulation of rna metabolic process GO:0051253 251 0.928
renal system development GO:0072001 72 0.926
Fly
circulatory system development GO:0072359 82 0.925
tube morphogenesis GO:0035239 191 0.922
Fly
embryonic morphogenesis GO:0048598 206 0.921
Fly
gland morphogenesis GO:0022612 145 0.913
Fly
embryonic pattern specification GO:0009880 174 0.902
urogenital system development GO:0001655 72 0.900
Fly
gastrulation GO:0007369 70 0.885
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.877
Worm Fly
digestive tract development GO:0048565 149 0.861
Fly
cell migration GO:0016477 238 0.857
cell cycle dna replication GO:0044786 23 0.850
Fly
embryonic hindgut morphogenesis GO:0048619 48 0.844
Fly
regulation of cell differentiation GO:0045595 302 0.841
central nervous system development GO:0007417 201 0.840
hindgut development GO:0061525 58 0.839
Fly
positive regulation of rna metabolic process GO:0051254 271 0.839
Worm Fly
neuron projection guidance GO:0097485 241 0.835
negative regulation of nucleic acid templated transcription GO:1903507 240 0.826
blastoderm segmentation GO:0007350 159 0.817
dorsal ventral pattern formation GO:0009953 133 0.816
positive regulation of transcription dna templated GO:0045893 266 0.810
Worm Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.805
heart formation GO:0060914 6 0.799
negative regulation of rna biosynthetic process GO:1902679 240 0.797
brain development GO:0007420 120 0.795
localization of cell GO:0051674 257 0.794
growth GO:0040007 359 0.792
Fly
negative regulation of biosynthetic process GO:0009890 277 0.787
regulation of cell fate commitment GO:0010453 29 0.784
positive regulation of nucleic acid templated transcription GO:1903508 266 0.784
Worm Fly
hindgut morphogenesis GO:0007442 58 0.783
Fly
dna endoreduplication GO:0042023 22 0.776
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.776
Worm Fly
gland development GO:0048732 191 0.768
Fly
regulation of multicellular organismal development GO:2000026 414 0.767
salivary gland morphogenesis GO:0007435 145 0.759
Fly
neuron fate determination GO:0048664 1 0.750
eye development GO:0001654 323 0.749
negative regulation of cell differentiation GO:0045596 143 0.747
cardiovascular system development GO:0072358 82 0.747
negative regulation of cellular metabolic process GO:0031324 382 0.742
axonogenesis GO:0007409 290 0.740
positive regulation of biosynthetic process GO:0009891 316 0.733
Worm Fly
axon development GO:0061564 297 0.732
respiratory system development GO:0060541 213 0.729
segment specification GO:0007379 33 0.726
positive regulation of macromolecule metabolic process GO:0010604 405 0.726
Worm Fly
mesodermal cell fate commitment GO:0001710 7 0.719
Fly
cardiac cell fate commitment GO:0060911 17 0.703
epithelial tube morphogenesis GO:0060562 88 0.702
Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.693
Fly
nephron morphogenesis GO:0072028 3 0.689
exocrine system development GO:0035272 162 0.686
Fly
negative regulation of neurogenesis GO:0050768 53 0.684
embryonic organ development GO:0048568 50 0.675
cell motility GO:0048870 251 0.674
regulation of neuron differentiation GO:0045664 103 0.673
digestive tract morphogenesis GO:0048546 127 0.672
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.662
developmental growth GO:0048589 280 0.653
Fly
cell proliferation GO:0008283 299 0.647
periodic partitioning GO:0007365 29 0.640
lateral inhibition GO:0046331 206 0.604
regulation of neurogenesis GO:0050767 158 0.600
regulation of cell proliferation GO:0042127 163 0.597
negative regulation of developmental process GO:0051093 201 0.570
Fly
sensory organ morphogenesis GO:0090596 260 0.566
multicellular organism growth GO:0035264 46 0.566
Fly
camera type eye development GO:0043010 4 0.564
regulation of developmental growth GO:0048638 174 0.559
Fly
morphogenesis of an epithelium GO:0002009 276 0.559
Fly
renal tubule morphogenesis GO:0061333 44 0.557
Fly
camera type eye morphogenesis GO:0048593 2 0.546
positive regulation of multicellular organismal process GO:0051240 143 0.545
neuroblast development GO:0014019 13 0.538
mesenchymal cell differentiation GO:0048762 1 0.520
torso signaling pathway GO:0008293 21 0.519
anterior posterior pattern specification GO:0009952 136 0.512
salivary gland development GO:0007431 162 0.512
Fly
neuroblast fate commitment GO:0014017 19 0.509
positive regulation of neurogenesis GO:0050769 41 0.486
forebrain development GO:0030900 2 0.481
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.480
Worm Fly
response to ecdysone GO:0035075 34 0.474
Fly
regulation of stem cell proliferation GO:0072091 40 0.472
cell fate specification GO:0001708 71 0.460
Worm
regulation of cardiac cell fate specification GO:2000043 8 0.459
regulation of protein metabolic process GO:0051246 256 0.454
neuroblast differentiation GO:0014016 29 0.454
epithelial cell differentiation GO:0030855 322 0.446
Fly
body morphogenesis GO:0010171 2 0.444
syncytium formation GO:0006949 43 0.440
germ cell migration GO:0008354 43 0.425
response to organic substance GO:0010033 284 0.422
Fly
regulation of multicellular organism growth GO:0040014 40 0.416
Fly
gastrulation with mouth forming first GO:0001703 36 0.412
regulation of neuroblast proliferation GO:1902692 34 0.412
neuroepithelial cell differentiation GO:0060563 6 0.406
Fly
positive regulation of cell proliferation GO:0008284 47 0.385
axon midline choice point recognition GO:0016199 26 0.384
positive regulation of developmental process GO:0051094 143 0.382
cardioblast cell fate commitment GO:0042684 14 0.377
regulation of protein modification process GO:0031399 112 0.372
organic acid metabolic process GO:0006082 103 0.369
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.363
Fly
chemotaxis GO:0006935 249 0.362
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.361
Worm Fly
apoptotic process GO:0006915 159 0.352
Fly
mesoderm formation GO:0001707 21 0.345
Fly
negative regulation of response to stimulus GO:0048585 258 0.344
regulation of mitotic cell cycle GO:0007346 190 0.344
ameboidal type cell migration GO:0001667 151 0.342
nephron tubule morphogenesis GO:0072078 3 0.340
neuron fate commitment GO:0048663 50 0.340
Worm
chromosome organization GO:0051276 360 0.339
dendrite development GO:0016358 204 0.338
Worm
stem cell proliferation GO:0072089 88 0.324
mesoderm morphogenesis GO:0048332 22 0.315
Fly
regulation of programmed cell death GO:0043067 152 0.311
Fly
cellular response to chemical stimulus GO:0070887 199 0.311
cell death GO:0008219 279 0.311
Fly
muscle structure development GO:0061061 224 0.308
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.303
Worm Fly
regulation of organ morphogenesis GO:2000027 78 0.298
regulation of cell development GO:0060284 215 0.289
connective tissue development GO:0061448 3 0.282
cardioblast cell fate specification GO:0042685 9 0.276
telencephalon development GO:0021537 2 0.274
formation of primary germ layer GO:0001704 24 0.274
Fly
negative regulation of cell development GO:0010721 62 0.269
limb development GO:0060173 1 0.261
eye photoreceptor cell differentiation GO:0001754 145 0.260
motor neuron axon guidance GO:0008045 58 0.254
dna replication GO:0006260 48 0.253
Fly
cellular protein modification process GO:0006464 438 0.251
protein acetylation GO:0006473 39 0.251
retina development in camera type eye GO:0060041 4 0.248
cell maturation GO:0048469 144 0.244
negative regulation of nervous system development GO:0051961 92 0.244
ectodermal placode morphogenesis GO:0071697 4 0.243
death GO:0016265 284 0.240
Fly
axis specification GO:0009798 167 0.239
r7 cell differentiation GO:0045466 43 0.232
chromatin organization GO:0006325 207 0.231
stem cell development GO:0048864 79 0.223
stem cell fate commitment GO:0048865 25 0.218
sensory perception GO:0007600 196 0.217
cardiocyte differentiation GO:0035051 29 0.210
cell fate determination GO:0001709 91 0.205
regulation of neural precursor cell proliferation GO:2000177 35 0.204
cell cell signaling involved in cell fate commitment GO:0045168 210 0.204
chromatin remodeling GO:0006338 72 0.201
neuroblast proliferation GO:0007405 74 0.198
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.196
Fly
neural precursor cell proliferation GO:0061351 75 0.196
anterior posterior axis specification GO:0009948 109 0.193
positive regulation of protein metabolic process GO:0051247 128 0.192
histone modification GO:0016570 106 0.190
amine metabolic process GO:0009308 12 0.190
terminal region determination GO:0007362 25 0.190
axon guidance GO:0007411 233 0.189
compound eye photoreceptor cell differentiation GO:0001751 140 0.188
chromatin modification GO:0016568 147 0.185
eye morphogenesis GO:0048592 260 0.184
cardioblast cell fate determination GO:0007510 3 0.183
regulation of cell fate specification GO:0042659 27 0.180
stem cell maintenance GO:0019827 67 0.174
regulation of cellular ketone metabolic process GO:0010565 3 0.173
multi multicellular organism process GO:0044706 123 0.172
dna metabolic process GO:0006259 227 0.172
Fly
neuroblast fate specification GO:0014018 2 0.169
regulation of nervous system development GO:0051960 248 0.169
salivary gland histolysis GO:0035070 88 0.168
Fly
spinal cord development GO:0021510 1 0.165
tissue migration GO:0090130 155 0.164
programmed cell death GO:0012501 257 0.164
Fly
neuron fate specification GO:0048665 12 0.163
Worm
regulation of cellular protein metabolic process GO:0032268 243 0.161
cellular amino acid metabolic process GO:0006520 61 0.158
kidney development GO:0001822 3 0.157
malpighian tubule development GO:0072002 64 0.157
Fly
appendage morphogenesis GO:0035107 397 0.152
gastrulation involving germ band extension GO:0010004 36 0.152
reproductive behavior GO:0019098 122 0.151
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.151
autophagic cell death GO:0048102 83 0.150
Fly
negative regulation of multicellular organismal process GO:0051241 142 0.139
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.138
regulation of growth GO:0040008 233 0.137
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.136
gliogenesis GO:0042063 80 0.135
negative regulation of growth GO:0045926 84 0.134
Fly
regulation of organelle organization GO:0033043 196 0.134
muscle organ development GO:0007517 127 0.133
regulation of neuron projection development GO:0010975 69 0.131
regulation of epithelial cell proliferation GO:0050678 4 0.130
nephron development GO:0072006 3 0.129
segment polarity determination GO:0007367 25 0.128
oxoacid metabolic process GO:0043436 103 0.126
limb morphogenesis GO:0035108 1 0.126
response to alcohol GO:0097305 95 0.125
Fly
methylation GO:0032259 47 0.125
cellular amine metabolic process GO:0044106 12 0.125
cellular ketone metabolic process GO:0042180 24 0.123
carboxylic acid metabolic process GO:0019752 92 0.123
posterior head segmentation GO:0035289 6 0.123
outflow tract morphogenesis GO:0003151 4 0.122
leg disc development GO:0035218 92 0.121
regulation of heart morphogenesis GO:2000826 3 0.119
salivary gland cell autophagic cell death GO:0035071 83 0.119
Fly
hindbrain development GO:0030902 2 0.118
reproductive structure development GO:0048608 74 0.116
positive regulation of cellular amine metabolic process GO:0033240 0 0.116
post embryonic appendage morphogenesis GO:0035120 385 0.116
embryonic axis specification GO:0000578 107 0.114
digestive tract mesoderm development GO:0007502 5 0.113
central nervous system neuron differentiation GO:0021953 8 0.111
negative regulation of signal transduction GO:0009968 206 0.110
notch signaling pathway GO:0007219 120 0.107
eye photoreceptor cell fate commitment GO:0042706 37 0.107
dendrite morphogenesis GO:0048813 199 0.106
developmental maturation GO:0021700 172 0.105
response to oxygen containing compound GO:1901700 200 0.105
Fly
intracellular signal transduction GO:0035556 300 0.103
muscle organ morphogenesis GO:0048644 7 0.103
regulation of histone modification GO:0031056 20 0.102
retina morphogenesis in camera type eye GO:0060042 2 0.100
imaginal disc derived appendage morphogenesis GO:0035114 395 0.100
response to wounding GO:0009611 94 0.100
skin development GO:0043588 65 0.100
imaginal disc derived wing morphogenesis GO:0007476 337 0.100
anterior posterior axis specification embryo GO:0008595 103 0.099
regulation of cell cycle GO:0051726 291 0.099
nephron epithelium morphogenesis GO:0072088 3 0.099
development of primary sexual characteristics GO:0045137 50 0.098
imaginal disc pattern formation GO:0007447 91 0.098
neuron recognition GO:0008038 101 0.097
positive regulation of cell communication GO:0010647 250 0.096
regulation of embryonic development GO:0045995 68 0.095
embryonic heart tube development GO:0035050 22 0.095
cellular response to organic substance GO:0071310 132 0.095
ectodermal placode development GO:0071696 4 0.095
catabolic process GO:0009056 409 0.095
regulation of anatomical structure morphogenesis GO:0022603 242 0.094
hemopoiesis GO:0030097 46 0.094
internal protein amino acid acetylation GO:0006475 38 0.093
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.093
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.093
single organism catabolic process GO:0044712 228 0.092
embryonic hemopoiesis GO:0035162 26 0.092
response to ketone GO:1901654 34 0.091
Fly
nephrocyte differentiation GO:0061319 12 0.091
regulation of cell projection organization GO:0031344 92 0.091
wing disc pattern formation GO:0035222 66 0.091
positive regulation of signaling GO:0023056 243 0.089
enzyme linked receptor protein signaling pathway GO:0007167 179 0.089
organic substance catabolic process GO:1901575 308 0.089
cell recognition GO:0008037 102 0.089
bmp signaling pathway GO:0030509 27 0.089
regulation of cell death GO:0010941 173 0.089
Fly
small molecule metabolic process GO:0044281 305 0.087
positive regulation of response to stimulus GO:0048584 323 0.087
axon choice point recognition GO:0016198 26 0.087
protein modification process GO:0036211 438 0.087
compound eye photoreceptor development GO:0042051 78 0.085
negative regulation of programmed cell death GO:0043069 72 0.084
Fly
positive regulation of cell differentiation GO:0045597 64 0.084
positive regulation of nervous system development GO:0051962 69 0.084
neuroblast fate determination GO:0007400 12 0.083
hematopoietic or lymphoid organ development GO:0048534 57 0.082
regulation of oocyte development GO:0060281 27 0.080
negative regulation of signaling GO:0023057 219 0.080
negative regulation of cell cycle process GO:0010948 109 0.079
regulation of molecular function GO:0065009 217 0.079
embryo development ending in birth or egg hatching GO:0009792 152 0.079
Worm
negative regulation of cell death GO:0060548 81 0.079
Fly
peptidyl lysine modification GO:0018205 57 0.079
tripartite regional subdivision GO:0007351 103 0.078
response to lipid GO:0033993 38 0.078
Fly
mesenchymal cell development GO:0014031 1 0.077
negative regulation of cell communication GO:0010648 223 0.077
positive regulation of protein modification process GO:0031401 58 0.077
regulation of antimicrobial humoral response GO:0002759 50 0.076
oocyte differentiation GO:0009994 145 0.075
positive regulation of signal transduction GO:0009967 223 0.075
mesodermal cell migration GO:0008078 7 0.075
protein complex biogenesis GO:0070271 201 0.075
imaginal disc derived appendage development GO:0048737 399 0.075
positive regulation of cellular protein metabolic process GO:0032270 118 0.074
gonad development GO:0008406 50 0.074
glandular epithelial cell differentiation GO:0002067 1 0.074
cell division GO:0051301 248 0.073
embryonic development via the syncytial blastoderm GO:0001700 148 0.073
positive regulation of neuron differentiation GO:0045666 26 0.072
positive regulation of programmed cell death GO:0043068 62 0.072
Fly
neurological system process GO:0050877 358 0.072
negative regulation of cell fate commitment GO:0010454 17 0.072
positive regulation of neural precursor cell proliferation GO:2000179 8 0.070
embryonic organ morphogenesis GO:0048562 5 0.070
regulation of epithelial cell differentiation GO:0030856 4 0.069
regulation of cellular amine metabolic process GO:0033238 3 0.069
protein alkylation GO:0008213 43 0.069
positive regulation of cell development GO:0010720 61 0.069
compound eye development GO:0048749 307 0.068
apoptotic process involved in morphogenesis GO:0060561 3 0.067
axonal defasciculation GO:0007414 12 0.066
regulation of glial cell proliferation GO:0060251 11 0.066
regulation of reproductive process GO:2000241 54 0.066
nephron epithelium development GO:0072009 3 0.065
regulation of intracellular signal transduction GO:1902531 236 0.064
protein localization GO:0008104 284 0.063
single organism biosynthetic process GO:0044711 206 0.063
Fly
foregut morphogenesis GO:0007440 10 0.063
regulation of retinal cell programmed cell death GO:0046668 18 0.063
nuclear division GO:0000280 332 0.062
multicellular organismal reproductive behavior GO:0033057 110 0.062
negative regulation of neuron differentiation GO:0045665 16 0.062
pigmentation GO:0043473 75 0.062
regulation of cell cycle phase transition GO:1901987 130 0.062
organic substance transport GO:0071702 257 0.062
pericardial nephrocyte differentiation GO:0061320 9 0.062
covalent chromatin modification GO:0016569 106 0.061
organ formation GO:0048645 39 0.061
response to other organism GO:0051707 293 0.061
syncytium formation by plasma membrane fusion GO:0000768 43 0.061
peptidyl lysine acetylation GO:0018394 39 0.060
kidney epithelium development GO:0072073 3 0.060
response to external biotic stimulus GO:0043207 293 0.059
columnar cuboidal epithelial cell development GO:0002066 249 0.058
cardioblast differentiation GO:0010002 20 0.058
reproductive system development GO:0061458 74 0.057
muscle tissue morphogenesis GO:0060415 2 0.057
peptide metabolic process GO:0006518 80 0.056
regulation of organ formation GO:0003156 3 0.055
ectodermal placode formation GO:0060788 4 0.055
spermatogenesis GO:0007283 200 0.055
open tracheal system development GO:0007424 204 0.055
oocyte axis specification GO:0007309 108 0.054
humoral immune response GO:0006959 117 0.054
protein acylation GO:0043543 42 0.054
oocyte development GO:0048599 124 0.053
response to abiotic stimulus GO:0009628 341 0.053
sex differentiation GO:0007548 81 0.053
regulation of chromosome organization GO:0033044 64 0.053
myoblast proliferation GO:0051450 3 0.052
regulation of myotube differentiation GO:0010830 6 0.051
positive regulation of developmental growth GO:0048639 62 0.051
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.050
single organism behavior GO:0044708 391 0.050
phagocytosis GO:0006909 215 0.050
response to pain GO:0048265 3 0.050
cellular catabolic process GO:0044248 372 0.050
chromosome segregation GO:0007059 157 0.049
photoreceptor cell differentiation GO:0046530 170 0.049
regulation of multi organism process GO:0043900 131 0.049
cell junction assembly GO:0034329 42 0.048
dorsal ventral axis specification GO:0009950 66 0.047
epidermal cell differentiation GO:0009913 51 0.047
negative regulation of stem cell differentiation GO:2000737 8 0.047
mesodermal cell fate specification GO:0007501 2 0.047
wing disc morphogenesis GO:0007472 344 0.047
determination of ventral identity GO:0048264 1 0.047
developmental induction GO:0031128 3 0.047
muscle cell differentiation GO:0042692 103 0.046
locomotory behavior GO:0007626 176 0.046
immune system development GO:0002520 57 0.045
sterol homeostasis GO:0055092 4 0.045
multi organism behavior GO:0051705 175 0.044
regulation of cell cycle process GO:0010564 181 0.044
phosphorylation GO:0016310 294 0.043
positive regulation of cellular component organization GO:0051130 156 0.043
response to endogenous stimulus GO:0009719 119 0.042
synaptic target recognition GO:0008039 45 0.042
positive regulation of stem cell proliferation GO:2000648 8 0.042
macromolecular complex assembly GO:0065003 256 0.041
developmental programmed cell death GO:0010623 138 0.041
Fly
compound eye photoreceptor fate commitment GO:0001752 36 0.041
kidney morphogenesis GO:0060993 3 0.041
histone methylation GO:0016571 40 0.041
immune response GO:0006955 246 0.040
regulation of glial cell differentiation GO:0045685 1 0.040
cell junction organization GO:0034330 57 0.040
mesenchyme development GO:0060485 9 0.040
histone acetylation GO:0016573 38 0.039
nephron tubule formation GO:0072079 3 0.039
regulation of stem cell differentiation GO:2000736 14 0.039
positive regulation of cell cycle GO:0045787 43 0.038
anterior commissure morphogenesis GO:0021960 2 0.038
protein transport GO:0015031 155 0.038
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.038
compound eye morphogenesis GO:0001745 249 0.037
establishment of protein localization GO:0045184 163 0.037
post embryonic hemopoiesis GO:0035166 17 0.037
taxis GO:0042330 304 0.037
positive regulation of lipid metabolic process GO:0045834 4 0.037
epidermis development GO:0008544 65 0.037
neuron migration GO:0001764 5 0.037
endocytosis GO:0006897 310 0.037
regulation of transport GO:0051049 181 0.036
regulation of humoral immune response GO:0002920 51 0.036
morphogenesis of embryonic epithelium GO:0016331 94 0.036
genital disc development GO:0035215 44 0.036
negative regulation of wnt signaling pathway GO:0030178 28 0.036
induction of programmed cell death by ecdysone GO:0035078 12 0.036
Fly
positive regulation of retinal cell programmed cell death GO:0046670 9 0.036
phosphatidylinositol mediated signaling GO:0048015 4 0.036
detection of chemical stimulus GO:0009593 93 0.035
adult locomotory behavior GO:0008344 76 0.035
oviposition GO:0018991 19 0.035
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.035
glial cell migration GO:0008347 31 0.035
secretion by cell GO:0032940 101 0.035
eye antennal disc development GO:0035214 60 0.035
smoothened signaling pathway GO:0007224 49 0.035
regulation of protein acetylation GO:1901983 7 0.034
hematopoietic progenitor cell differentiation GO:0002244 1 0.034
somatic stem cell division GO:0048103 37 0.034
response to hypoxia GO:0001666 53 0.034
proximal distal pattern formation GO:0009954 15 0.034
cell growth GO:0016049 108 0.034
Fly
appendage development GO:0048736 401 0.034
photoreceptor cell fate commitment GO:0046552 41 0.034
male gamete generation GO:0048232 201 0.033
lamellipodium organization GO:0097581 21 0.033
multi organism reproductive behavior GO:0044705 121 0.033
synaptic transmission GO:0007268 288 0.033
regulation of notch signaling pathway GO:0008593 100 0.033
cardiac cell fate determination GO:0060913 3 0.033
regulation of chromatin organization GO:1902275 32 0.032
rhythmic process GO:0048511 106 0.032
regulation of cell morphogenesis GO:0022604 163 0.032
induction of programmed cell death GO:0012502 12 0.032
Fly
regulation of bmp signaling pathway GO:0030510 23 0.032
cellular macromolecule catabolic process GO:0044265 136 0.031
regulation of phosphorus metabolic process GO:0051174 210 0.031
negative regulation of immune system process GO:0002683 50 0.031
muscle tissue development GO:0060537 30 0.031
cellular macromolecular complex assembly GO:0034622 153 0.031
pharynx development GO:0060465 1 0.031
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.031
nephron tubule development GO:0072080 3 0.031
regulation of cellular response to stress GO:0080135 89 0.030
regulation of syncytium formation by plasma membrane fusion GO:0060142 6 0.030
chemosensory behavior GO:0007635 106 0.030
membrane fusion GO:0061025 42 0.030
glial cell proliferation GO:0014009 13 0.030
organonitrogen compound metabolic process GO:1901564 318 0.030
regulation of response to stress GO:0080134 200 0.029
cellular response to dna damage stimulus GO:0006974 223 0.029
regulation of synaptic activity GO:0060025 9 0.029
antimicrobial peptide biosynthetic process GO:0002777 38 0.029
regulation of muscle cell differentiation GO:0051147 8 0.029
fat soluble vitamin biosynthetic process GO:0042362 1 0.029
peptidyl amino acid modification GO:0018193 105 0.029
regulation of synapse structure and activity GO:0050803 128 0.028
signal transduction in response to dna damage GO:0042770 3 0.028
epithelial cell migration open tracheal system GO:0007427 32 0.028

slp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.324
disease of cellular proliferation DOID:14566 0 0.324
organ system cancer DOID:0050686 0 0.324
disease of anatomical entity DOID:7 0 0.275
waardenburg s syndrome DOID:9258 0 0.112
musculoskeletal system disease DOID:17 0 0.106
cardiovascular system disease DOID:1287 0 0.084
congenital heart disease DOID:1682 0 0.058
heart disease DOID:114 0 0.058
bone development disease DOID:0080006 0 0.058
bone disease DOID:0080001 0 0.058
connective tissue disease DOID:65 0 0.058
urinary system disease DOID:18 0 0.034