Drosophila melanogaster

12 known processes

Spn (Dmel_CG16757)

Spinophilin

(Aliases: CG16757,EL62,c62E-5,Dmel\CG16757,BcDNA:GM16129,l(3)06911,spn,E62)

Spn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chemosensory behavior GO:0007635 106 0.980
single organism behavior GO:0044708 391 0.887
inter male aggressive behavior GO:0002121 60 0.877
olfactory behavior GO:0042048 97 0.791
negative regulation of cellular metabolic process GO:0031324 382 0.714
organic cyclic compound catabolic process GO:1901361 168 0.515
cellular response to dna damage stimulus GO:0006974 223 0.493
regulation of intracellular signal transduction GO:1902531 236 0.460
negative regulation of rna biosynthetic process GO:1902679 240 0.428
positive regulation of gene expression GO:0010628 290 0.356
response to oxygen containing compound GO:1901700 200 0.355
aggressive behavior GO:0002118 63 0.355
nucleobase containing compound catabolic process GO:0034655 165 0.328
response to nitrogen compound GO:1901698 90 0.305
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.289
negative regulation of developmental process GO:0051093 201 0.285
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.281
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.281
negative regulation of gene expression GO:0010629 387 0.269
carbohydrate derivative metabolic process GO:1901135 217 0.254
positive regulation of signaling GO:0023056 243 0.235
glycosyl compound catabolic process GO:1901658 112 0.229
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.222
regulation of cellular response to stress GO:0080135 89 0.217
multi organism behavior GO:0051705 175 0.208
regulation of protein metabolic process GO:0051246 256 0.207
macromolecular complex assembly GO:0065003 256 0.207
response to organonitrogen compound GO:0010243 75 0.202
imaginal disc derived wing morphogenesis GO:0007476 337 0.196
heterocycle catabolic process GO:0046700 166 0.192
regulation of localization GO:0032879 275 0.189
regulation of cytoskeleton organization GO:0051493 89 0.187
nucleotide metabolic process GO:0009117 161 0.181
cellular protein modification process GO:0006464 438 0.169
aromatic compound catabolic process GO:0019439 166 0.168
imaginal disc derived appendage morphogenesis GO:0035114 395 0.167
purine ribonucleotide metabolic process GO:0009150 145 0.167
protein modification process GO:0036211 438 0.167
negative regulation of cellular biosynthetic process GO:0031327 277 0.157
regulation of response to stress GO:0080134 200 0.139
response to abiotic stimulus GO:0009628 341 0.138
nucleotide catabolic process GO:0009166 109 0.132
wing disc morphogenesis GO:0007472 344 0.131
cellular catabolic process GO:0044248 372 0.129
intracellular signal transduction GO:0035556 300 0.129
adult behavior GO:0030534 137 0.125
chromosome organization GO:0051276 360 0.122
taxis GO:0042330 304 0.122
negative regulation of cell differentiation GO:0045596 143 0.121
single organism catabolic process GO:0044712 228 0.119
response to organic substance GO:0010033 284 0.115
organophosphate metabolic process GO:0019637 195 0.112
imaginal disc derived appendage development GO:0048737 399 0.112
head development GO:0060322 135 0.107
regulation of transport GO:0051049 181 0.107
response to organic cyclic compound GO:0014070 89 0.107
protein complex assembly GO:0006461 200 0.105
regulation of gene silencing GO:0060968 63 0.098
response to temperature stimulus GO:0009266 106 0.097
organonitrogen compound catabolic process GO:1901565 128 0.096
ribonucleoside metabolic process GO:0009119 127 0.094
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.094
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.094
appendage morphogenesis GO:0035107 397 0.091
negative regulation of transcription dna templated GO:0045892 237 0.090
translation GO:0006412 69 0.090
ribonucleotide catabolic process GO:0009261 109 0.088
actin cytoskeleton organization GO:0030036 206 0.088
purine nucleotide catabolic process GO:0006195 109 0.087
negative regulation of growth GO:0045926 84 0.086
regulation of cell morphogenesis GO:0022604 163 0.086
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.085
ribose phosphate metabolic process GO:0019693 145 0.084
purine ribonucleotide catabolic process GO:0009154 109 0.083
negative regulation of biosynthetic process GO:0009890 277 0.083
nucleoside phosphate metabolic process GO:0006753 162 0.083
cellular nitrogen compound catabolic process GO:0044270 165 0.083
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.082
positive regulation of developmental process GO:0051094 143 0.082
regulation of cellular protein metabolic process GO:0032268 243 0.081
regulation of nucleoside metabolic process GO:0009118 50 0.080
regulation of gene expression epigenetic GO:0040029 128 0.078
regulation of hydrolase activity GO:0051336 97 0.078
ribonucleoside catabolic process GO:0042454 112 0.074
regulation of gtp catabolic process GO:0033124 44 0.072
positive regulation of signal transduction GO:0009967 223 0.071
nucleobase containing small molecule metabolic process GO:0055086 174 0.071
regulation of cellular localization GO:0060341 136 0.071
purine ribonucleoside catabolic process GO:0046130 112 0.070
positive regulation of cellular catabolic process GO:0031331 95 0.070
organic substance catabolic process GO:1901575 308 0.069
nucleoside triphosphate metabolic process GO:0009141 120 0.069
purine containing compound metabolic process GO:0072521 155 0.069
cellular macromolecular complex assembly GO:0034622 153 0.068
nucleoside triphosphate catabolic process GO:0009143 108 0.067
purine nucleoside triphosphate metabolic process GO:0009144 119 0.067
purine nucleoside catabolic process GO:0006152 112 0.067
regulation of response to external stimulus GO:0032101 115 0.066
cell death GO:0008219 279 0.066
actin filament based process GO:0030029 220 0.064
regulation of catalytic activity GO:0050790 185 0.063
ribonucleoside triphosphate catabolic process GO:0009203 108 0.063
positive regulation of biosynthetic process GO:0009891 316 0.063
purine containing compound catabolic process GO:0072523 112 0.063
positive regulation of macromolecule metabolic process GO:0010604 405 0.062
regulation of nervous system development GO:0051960 248 0.062
cellular response to oxygen containing compound GO:1901701 79 0.061
regulation of organelle organization GO:0033043 196 0.061
purine ribonucleoside metabolic process GO:0046128 127 0.058
nucleoside metabolic process GO:0009116 127 0.058
positive regulation of cellular biosynthetic process GO:0031328 316 0.057
purine nucleoside triphosphate catabolic process GO:0009146 108 0.057
regulation of cell proliferation GO:0042127 163 0.057
response to oxidative stress GO:0006979 86 0.056
gtp metabolic process GO:0046039 72 0.056
protein phosphorylation GO:0006468 169 0.056
negative regulation of multicellular organismal process GO:0051241 142 0.055
positive regulation of cellular component organization GO:0051130 156 0.055
regulation of cell differentiation GO:0045595 302 0.055
organonitrogen compound metabolic process GO:1901564 318 0.054
positive regulation of transport GO:0051050 92 0.054
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.053
purine nucleoside metabolic process GO:0042278 127 0.052
response to extracellular stimulus GO:0009991 116 0.052
ribonucleotide metabolic process GO:0009259 145 0.052
embryonic development via the syncytial blastoderm GO:0001700 148 0.049
phosphorylation GO:0016310 294 0.049
positive regulation of response to stimulus GO:0048584 323 0.048
regulation of multicellular organismal development GO:2000026 414 0.048
catabolic process GO:0009056 409 0.047
circulatory system development GO:0072359 82 0.047
actin filament organization GO:0007015 126 0.046
single organism cellular localization GO:1902580 180 0.046
glycosyl compound metabolic process GO:1901657 127 0.046
appendage development GO:0048736 401 0.044
purine nucleoside monophosphate metabolic process GO:0009126 50 0.044
regulation of multi organism process GO:0043900 131 0.043
stem cell development GO:0048864 79 0.043
small molecule metabolic process GO:0044281 305 0.042
regulation of jnk cascade GO:0046328 40 0.042
regulation of cell development GO:0060284 215 0.042
mrna metabolic process GO:0016071 124 0.041
positive regulation of cell communication GO:0010647 250 0.041
response to endogenous stimulus GO:0009719 119 0.041
regulation of phosphate metabolic process GO:0019220 210 0.041
negative regulation of rna metabolic process GO:0051253 251 0.040
negative regulation of translation GO:0017148 28 0.040
immune system process GO:0002376 347 0.039
regulation of mapk cascade GO:0043408 92 0.039
positive regulation of molecular function GO:0044093 136 0.039
regulation of catabolic process GO:0009894 170 0.038
regulation of neuron differentiation GO:0045664 103 0.038
negative regulation of gene expression epigenetic GO:0045814 77 0.038
rna splicing GO:0008380 83 0.038
regulation of cellular catabolic process GO:0031329 157 0.038
ribonucleoside triphosphate metabolic process GO:0009199 119 0.037
positive regulation of rna metabolic process GO:0051254 271 0.037
embryonic morphogenesis GO:0048598 206 0.037
apoptotic process GO:0006915 159 0.036
muscle structure development GO:0061061 224 0.036
posttranscriptional regulation of gene expression GO:0010608 145 0.036
regulation of stress activated mapk cascade GO:0032872 41 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.036
organelle localization GO:0051640 148 0.035
response to alcohol GO:0097305 95 0.035
establishment of localization in cell GO:0051649 402 0.034
regulation of molecular function GO:0065009 217 0.033
covalent chromatin modification GO:0016569 106 0.033
regulation of protein modification process GO:0031399 112 0.033
cellular protein complex assembly GO:0043623 71 0.033
positive regulation of protein modification process GO:0031401 58 0.033
positive regulation of catabolic process GO:0009896 105 0.032
positive regulation of phosphate metabolic process GO:0045937 139 0.031
immune response GO:0006955 246 0.031
response to inorganic substance GO:0010035 44 0.031
cell migration GO:0016477 238 0.031
negative regulation of intracellular signal transduction GO:1902532 57 0.031
positive regulation of transcription dna templated GO:0045893 266 0.031
positive regulation of organelle organization GO:0010638 65 0.030
regulation of purine nucleotide catabolic process GO:0033121 48 0.030
regulation of nucleotide catabolic process GO:0030811 48 0.030
response to alkaloid GO:0043279 26 0.029
autophagy GO:0006914 108 0.029
negative regulation of nucleic acid templated transcription GO:1903507 240 0.029
protein complex biogenesis GO:0070271 201 0.029
regulation of immune system process GO:0002682 176 0.028
signal transduction by phosphorylation GO:0023014 107 0.028
positive regulation of nucleotide catabolic process GO:0030813 46 0.028
response to biotic stimulus GO:0009607 294 0.027
protein localization to organelle GO:0033365 82 0.027
histone modification GO:0016570 106 0.027
response to ethanol GO:0045471 59 0.027
dendrite development GO:0016358 204 0.027
regulation of cellular component biogenesis GO:0044087 201 0.026
positive regulation of secretion GO:0051047 22 0.026
endomembrane system organization GO:0010256 119 0.026
positive regulation of catalytic activity GO:0043085 118 0.026
response to nutrient levels GO:0031667 114 0.026
negative regulation of developmental growth GO:0048640 64 0.025
positive regulation of protein complex assembly GO:0031334 22 0.025
learning GO:0007612 75 0.025
mapk cascade GO:0000165 107 0.025
behavioral response to ethanol GO:0048149 49 0.025
stress activated protein kinase signaling cascade GO:0031098 55 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.024
regulation of cell death GO:0010941 173 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.024
adult locomotory behavior GO:0008344 76 0.024
biological adhesion GO:0022610 138 0.024
negative regulation of protein metabolic process GO:0051248 85 0.023
dna metabolic process GO:0006259 227 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
synaptic growth at neuromuscular junction GO:0051124 119 0.023
organophosphate catabolic process GO:0046434 112 0.023
chromatin organization GO:0006325 207 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
atp metabolic process GO:0046034 49 0.023
membrane organization GO:0061024 112 0.023
pole plasm mrna localization GO:0019094 49 0.023
positive regulation of hydrolase activity GO:0051345 78 0.023
body morphogenesis GO:0010171 2 0.023
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.023
embryo development ending in birth or egg hatching GO:0009792 152 0.023
response to external biotic stimulus GO:0043207 293 0.023
ras protein signal transduction GO:0007265 88 0.022
cellular macromolecule localization GO:0070727 220 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
imaginal disc derived leg morphogenesis GO:0007480 80 0.022
telencephalon development GO:0021537 2 0.022
chromatin modification GO:0016568 147 0.022
cell proliferation GO:0008283 299 0.021
cytoplasmic transport GO:0016482 130 0.021
negative regulation of cellular protein metabolic process GO:0032269 85 0.021
positive regulation of cellular protein metabolic process GO:0032270 118 0.021
negative regulation of nervous system development GO:0051961 92 0.021
sex differentiation GO:0007548 81 0.021
regulation of reproductive process GO:2000241 54 0.021
regulation of phosphorylation GO:0042325 147 0.021
programmed cell death GO:0012501 257 0.020
forebrain development GO:0030900 2 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
peptidyl amino acid modification GO:0018193 105 0.020
mrna splicing via spliceosome GO:0000398 73 0.020
brain development GO:0007420 120 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.019
startle response GO:0001964 16 0.019
regulation of cytoplasmic transport GO:1903649 47 0.019
regulation of programmed cell death GO:0043067 152 0.019
regulation of cell shape GO:0008360 113 0.018
stress activated mapk cascade GO:0051403 52 0.018
protein localization GO:0008104 284 0.018
regulation of histone deacetylation GO:0031063 2 0.018
guanosine containing compound metabolic process GO:1901068 74 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
chemotaxis GO:0006935 249 0.017
stem cell maintenance GO:0019827 67 0.017
secretion GO:0046903 109 0.017
long term memory GO:0007616 62 0.017
single organism intracellular transport GO:1902582 207 0.017
epithelial cell differentiation GO:0030855 322 0.016
rna splicing via transesterification reactions GO:0000375 73 0.016
positive regulation of ras gtpase activity GO:0032320 36 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
vesicle mediated transport GO:0016192 381 0.016
synaptic transmission GO:0007268 288 0.016
regulation of gtpase activity GO:0043087 44 0.016
nucleoside catabolic process GO:0009164 112 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
growth GO:0040007 359 0.016
regulation of protein phosphorylation GO:0001932 64 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.016
rna catabolic process GO:0006401 37 0.016
endocytosis GO:0006897 310 0.016
feeding behavior GO:0007631 50 0.015
regulation of embryonic development GO:0045995 68 0.015
larval development GO:0002164 104 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
multicellular organismal aging GO:0010259 140 0.015
amine metabolic process GO:0009308 12 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
ribonucleoprotein complex assembly GO:0022618 23 0.014
chromosome segregation GO:0007059 157 0.014
regulation of rna splicing GO:0043484 69 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
dendrite morphogenesis GO:0048813 199 0.014
purine nucleoside monophosphate catabolic process GO:0009128 38 0.014
response to lipopolysaccharide GO:0032496 4 0.014
ribonucleoside monophosphate metabolic process GO:0009161 51 0.014
intracellular transport GO:0046907 228 0.014
organic substance transport GO:0071702 257 0.014
positive regulation of protein phosphorylation GO:0001934 34 0.014
wnt signaling pathway GO:0016055 98 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
neurological system process GO:0050877 358 0.014
regulation of neurogenesis GO:0050767 158 0.014
axis specification GO:0009798 167 0.014
cellular protein localization GO:0034613 160 0.014
cell adhesion GO:0007155 136 0.014
methylation GO:0032259 47 0.014
response to gravity GO:0009629 26 0.013
jnk cascade GO:0007254 50 0.013
mrna processing GO:0006397 104 0.013
regulation of anatomical structure size GO:0090066 163 0.013
establishment of protein localization GO:0045184 163 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
carbohydrate metabolic process GO:0005975 82 0.013
activation of protein kinase activity GO:0032147 12 0.013
positive regulation of cell migration GO:0030335 2 0.013
associative learning GO:0008306 65 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
positive regulation of gtp catabolic process GO:0033126 43 0.013
locomotory behavior GO:0007626 176 0.013
negative regulation of neurogenesis GO:0050768 53 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
dorsal appendage formation GO:0046843 47 0.012
regulation of actin cytoskeleton organization GO:0032956 42 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.012
rna transport GO:0050658 46 0.012
regulation of vesicle mediated transport GO:0060627 59 0.012
intracellular protein transport GO:0006886 104 0.012
response to other organism GO:0051707 293 0.012
death GO:0016265 284 0.012
regulation of secretion GO:0051046 44 0.012
positive regulation of nucleotide metabolic process GO:0045981 55 0.012
regulation of tor signaling GO:0032006 21 0.012
response to peptide hormone GO:0043434 29 0.012
positive regulation of gtpase activity GO:0043547 43 0.011
negative regulation of phosphate metabolic process GO:0045936 45 0.011
mrna catabolic process GO:0006402 33 0.011
response to lipid GO:0033993 38 0.011
regulation of developmental growth GO:0048638 174 0.011
aging GO:0007568 143 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
secretion by cell GO:0032940 101 0.011
phenol containing compound metabolic process GO:0018958 57 0.011
establishment of organelle localization GO:0051656 122 0.011
axonogenesis GO:0007409 290 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
spindle organization GO:0007051 253 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
spermatogenesis GO:0007283 200 0.011
jak stat cascade GO:0007259 49 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
positive regulation of cytoskeleton organization GO:0051495 21 0.011
positive regulation of jnk cascade GO:0046330 16 0.011
regulation of growth GO:0040008 233 0.011
anterior posterior axis specification GO:0009948 109 0.011
developmental maturation GO:0021700 172 0.011
regulation of translation GO:0006417 56 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
response to ketone GO:1901654 34 0.010
establishment of protein localization to organelle GO:0072594 62 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010
regulation of protein complex assembly GO:0043254 42 0.010
reproductive system development GO:0061458 74 0.010
developmental growth GO:0048589 280 0.010
rna localization GO:0006403 115 0.010

Spn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.013
central nervous system disease DOID:331 0 0.010