Drosophila melanogaster

69 known processes

Roc1a (Dmel_CG16982)

CG16982 gene product from transcript CG16982-RB

(Aliases: dRoc1,CG16982,dRoc1a,dRbx1,Rbx1/Roc,Dmel\CG16982,BEST:CK01110,CK01110,ROC1,anon-EST:Posey65,Roc1alpha,EG:115C2.11,Rbx1)

Roc1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.343
positive regulation of transcription dna templated GO:0045893 266 0.208
response to organic substance GO:0010033 284 0.206
protein ubiquitination GO:0016567 70 0.192
catabolic process GO:0009056 409 0.140
Human Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.131
cellular protein modification process GO:0006464 438 0.128
positive regulation of macromolecule metabolic process GO:0010604 405 0.121
Fly
cell proliferation GO:0008283 299 0.113
mitotic spindle organization GO:0007052 220 0.106
embryo development ending in birth or egg hatching GO:0009792 152 0.105
positive regulation of cellular biosynthetic process GO:0031328 316 0.102
chromatin organization GO:0006325 207 0.099
aromatic compound catabolic process GO:0019439 166 0.098
positive regulation of rna metabolic process GO:0051254 271 0.093
positive regulation of gene expression GO:0010628 290 0.091
macromolecule catabolic process GO:0009057 161 0.089
Human Yeast
transcription from rna polymerase ii promoter GO:0006366 368 0.086
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.083
regulation of multicellular organismal development GO:2000026 414 0.081
positive regulation of rna biosynthetic process GO:1902680 266 0.078
negative regulation of response to stimulus GO:0048585 258 0.078
cellular response to chemical stimulus GO:0070887 199 0.078
vesicle mediated transport GO:0016192 381 0.075
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.073
muscle structure development GO:0061061 224 0.069
cellular macromolecule catabolic process GO:0044265 136 0.066
Human Yeast
single organism behavior GO:0044708 391 0.065
regulation of cell cycle GO:0051726 291 0.063
regulation of organelle organization GO:0033043 196 0.063
rna processing GO:0006396 147 0.062
aging GO:0007568 143 0.061
cellular response to organic substance GO:0071310 132 0.061
heterocycle catabolic process GO:0046700 166 0.057
reproductive structure development GO:0048608 74 0.056
multicellular organismal aging GO:0010259 140 0.056
regulation of cellular protein metabolic process GO:0032268 243 0.055
Fly
negative regulation of signaling GO:0023057 219 0.055
spindle organization GO:0007051 253 0.055
protein modification process GO:0036211 438 0.054
organelle fission GO:0048285 340 0.053
cellular catabolic process GO:0044248 372 0.052
Human Yeast
molting cycle GO:0042303 56 0.049
regulation of catabolic process GO:0009894 170 0.049
determination of adult lifespan GO:0008340 137 0.048
death GO:0016265 284 0.048
Fly
anterior posterior axis specification embryo GO:0008595 103 0.047
body morphogenesis GO:0010171 2 0.046
regulation of chromosome organization GO:0033044 64 0.046
epithelial cell differentiation GO:0030855 322 0.045
regulation of cell cycle process GO:0010564 181 0.045
negative regulation of signal transduction GO:0009968 206 0.045
regulation of cell development GO:0060284 215 0.044
regionalization GO:0003002 416 0.044
organic substance catabolic process GO:1901575 308 0.042
Human Yeast
positive regulation of protein metabolic process GO:0051247 128 0.042
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.041
cell death GO:0008219 279 0.041
Fly
endocytosis GO:0006897 310 0.040
regulation of cellular catabolic process GO:0031329 157 0.040
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.039
organophosphate metabolic process GO:0019637 195 0.039
organonitrogen compound metabolic process GO:1901564 318 0.039
organic cyclic compound catabolic process GO:1901361 168 0.039
nuclear division GO:0000280 332 0.037
positive regulation of biosynthetic process GO:0009891 316 0.037
modification dependent protein catabolic process GO:0019941 78 0.037
Human Yeast
response to other organism GO:0051707 293 0.037
rna splicing via transesterification reactions GO:0000375 73 0.037
regulation of anatomical structure morphogenesis GO:0022603 242 0.037
regulation of protein metabolic process GO:0051246 256 0.036
Fly
rna catabolic process GO:0006401 37 0.035
nucleobase containing compound catabolic process GO:0034655 165 0.035
regulation of cell differentiation GO:0045595 302 0.034
small molecule metabolic process GO:0044281 305 0.034
cell division GO:0051301 248 0.033
regulation of proteolysis GO:0030162 87 0.033
Fly
rna splicing GO:0008380 83 0.032
proteolysis GO:0006508 192 0.032
mitotic spindle elongation GO:0000022 81 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
enzyme linked receptor protein signaling pathway GO:0007167 179 0.032
mrna metabolic process GO:0016071 124 0.032
regulation of nuclear division GO:0051783 58 0.031
humoral immune response GO:0006959 117 0.030
positive regulation of cellular protein metabolic process GO:0032270 118 0.030
Fly
intracellular mrna localization GO:0008298 66 0.030
protein catabolic process GO:0030163 101 0.029
Human Yeast
salivary gland morphogenesis GO:0007435 145 0.029
negative regulation of gene expression GO:0010629 387 0.029
regulation of cell morphogenesis GO:0022604 163 0.029
embryonic pattern specification GO:0009880 174 0.029
gonad development GO:0008406 50 0.027
cell projection assembly GO:0030031 94 0.027
alternative mrna splicing via spliceosome GO:0000380 60 0.027
protein modification by small protein conjugation or removal GO:0070647 106 0.026
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.026
protein dna complex assembly GO:0065004 63 0.025
mrna processing GO:0006397 104 0.025
cellular protein catabolic process GO:0044257 83 0.025
Human Yeast
regulation of gene expression epigenetic GO:0040029 128 0.025
neurological system process GO:0050877 358 0.023
regulation of meiosis GO:0040020 3 0.023
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.023
ovarian follicle cell development GO:0030707 248 0.023
negative regulation of cell differentiation GO:0045596 143 0.023
secretion by cell GO:0032940 101 0.023
anterior posterior pattern specification GO:0009952 136 0.023
cellular nitrogen compound catabolic process GO:0044270 165 0.023
gene silencing GO:0016458 138 0.022
regulation of cell proliferation GO:0042127 163 0.022
mrna splicing via spliceosome GO:0000398 73 0.022
tissue morphogenesis GO:0048729 297 0.022
segmentation GO:0035282 207 0.021
chromatin modification GO:0016568 147 0.021
regulation of protein modification process GO:0031399 112 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
intracellular signal transduction GO:0035556 300 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
actin cytoskeleton organization GO:0030036 206 0.021
protein secretion GO:0009306 45 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
cellular amine metabolic process GO:0044106 12 0.020
embryonic axis specification GO:0000578 107 0.020
dendrite morphogenesis GO:0048813 199 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
muscle organ development GO:0007517 127 0.020
regulation of mrna metabolic process GO:1903311 72 0.020
actin filament based process GO:0030029 220 0.020
regulation of cell division GO:0051302 72 0.020
spindle elongation GO:0051231 83 0.019
secretion GO:0046903 109 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
development of primary sexual characteristics GO:0045137 50 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
small gtpase mediated signal transduction GO:0007264 88 0.018
cell motility GO:0048870 251 0.018
Fly
histone modification GO:0016570 106 0.018
gland morphogenesis GO:0022612 145 0.018
organic substance transport GO:0071702 257 0.018
protein complex biogenesis GO:0070271 201 0.017
regulation of catalytic activity GO:0050790 185 0.017
Fly
larval development GO:0002164 104 0.017
nitrogen compound transport GO:0071705 85 0.017
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
cytoplasm organization GO:0007028 64 0.017
ameboidal type cell migration GO:0001667 151 0.017
reproductive system development GO:0061458 74 0.017
morphogenesis of an epithelium GO:0002009 276 0.016
anterior posterior axis specification GO:0009948 109 0.016
cytoplasmic transport GO:0016482 130 0.016
establishment of localization in cell GO:0051649 402 0.016
tissue migration GO:0090130 155 0.016
positive regulation of catabolic process GO:0009896 105 0.016
regulation of programmed cell death GO:0043067 152 0.016
Fly
negative regulation of cell communication GO:0010648 223 0.016
cell maturation GO:0048469 144 0.016
exocrine system development GO:0035272 162 0.016
immune response GO:0006955 246 0.015
epithelium migration GO:0090132 148 0.015
phagocytosis GO:0006909 215 0.015
regulation of hydrolase activity GO:0051336 97 0.015
Fly
sex differentiation GO:0007548 81 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
regulation of cell death GO:0010941 173 0.015
Fly
adult behavior GO:0030534 137 0.015
tripartite regional subdivision GO:0007351 103 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
regulation of rna splicing GO:0043484 69 0.015
chemosensory behavior GO:0007635 106 0.014
positive regulation of signal transduction GO:0009967 223 0.014
developmental programmed cell death GO:0010623 138 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
Human Yeast
negative regulation of nervous system development GO:0051961 92 0.014
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.014
gene silencing by mirna GO:0035195 22 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
programmed cell death GO:0012501 257 0.014
Fly
autophagy GO:0006914 108 0.014
protein dna complex subunit organization GO:0071824 86 0.013
regulation of molecular function GO:0065009 217 0.013
Fly
regulation of phosphate metabolic process GO:0019220 210 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.013
dendrite development GO:0016358 204 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
positive regulation of protein modification process GO:0031401 58 0.013
protein acylation GO:0043543 42 0.013
covalent chromatin modification GO:0016569 106 0.013
purine containing compound metabolic process GO:0072521 155 0.013
amine metabolic process GO:0009308 12 0.013
protein localization GO:0008104 284 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
imaginal disc derived appendage morphogenesis GO:0035114 395 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.012
cation transport GO:0006812 110 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
response to biotic stimulus GO:0009607 294 0.012
mrna catabolic process GO:0006402 33 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
mrna cis splicing via spliceosome GO:0045292 1 0.011
axis specification GO:0009798 167 0.011
centrosome organization GO:0051297 163 0.011
salivary gland development GO:0007431 162 0.011
regulation of nervous system development GO:0051960 248 0.011
regulation of mrna processing GO:0050684 71 0.011
learning or memory GO:0007611 141 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
regulation of cell shape GO:0008360 113 0.011
response to heat GO:0009408 63 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.011
regulation of cell projection organization GO:0031344 92 0.011
cellularization GO:0007349 90 0.010
regulation of apoptotic process GO:0042981 130 0.010
Fly
regulation of neurogenesis GO:0050767 158 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
regulation of response to stress GO:0080134 200 0.010
modification dependent macromolecule catabolic process GO:0043632 79 0.010
Human Yeast
single organism catabolic process GO:0044712 228 0.010
apoptotic process GO:0006915 159 0.010
Fly
negative regulation of biosynthetic process GO:0009890 277 0.010
regulation of mitotic cell cycle GO:0007346 190 0.010

Roc1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038