Drosophila melanogaster

29 known processes

obst-A (Dmel_CG17052)

obstructor-A

(Aliases: Dmel\CG17052,obst,CG17052)

obst-A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of tube length open tracheal system GO:0035159 24 0.840
chitin based cuticle development GO:0040003 49 0.669
regulation of tube architecture open tracheal system GO:0035152 68 0.523
regulation of tube size open tracheal system GO:0035151 43 0.360
developmental growth GO:0048589 280 0.351
open tracheal system development GO:0007424 204 0.269
respiratory system development GO:0060541 213 0.257
glucosamine containing compound metabolic process GO:1901071 9 0.203
extracellular matrix disassembly GO:0022617 4 0.203
chitin metabolic process GO:0006030 7 0.153
negative regulation of response to stimulus GO:0048585 258 0.144
regulation of tube size GO:0035150 46 0.138
growth GO:0040007 359 0.133
regulation of tube diameter open tracheal system GO:0035158 11 0.120
response to monosaccharide GO:0034284 4 0.118
cuticle development GO:0042335 86 0.118
intracellular signal transduction GO:0035556 300 0.118
terminal branching open tracheal system GO:0007430 17 0.103
indole containing compound biosynthetic process GO:0042435 4 0.102
negative regulation of gene expression GO:0010629 387 0.102
trachea development GO:0060438 29 0.099
extracellular structure organization GO:0043062 46 0.098
regulation of anatomical structure size GO:0090066 163 0.094
response to oxygen containing compound GO:1901700 200 0.092
positive regulation of signaling GO:0023056 243 0.090
positive regulation of response to stimulus GO:0048584 323 0.088
positive regulation of signal transduction GO:0009967 223 0.085
single organism behavior GO:0044708 391 0.080
regulation of extracellular matrix organization GO:1903053 4 0.077
epithelial cell migration open tracheal system GO:0007427 32 0.074
regulation of tube diameter GO:0035296 14 0.072
response to organic substance GO:0010033 284 0.069
trachea morphogenesis GO:0060439 22 0.068
cellular component disassembly GO:0022411 46 0.068
immune response GO:0006955 246 0.066
regulation of multicellular organismal development GO:2000026 414 0.064
g protein coupled receptor signaling pathway GO:0007186 136 0.064
amino sugar metabolic process GO:0006040 10 0.060
taxis GO:0042330 304 0.060
vesicle mediated transport GO:0016192 381 0.059
immune system process GO:0002376 347 0.058
response to glucose GO:0009749 2 0.056
compound eye morphogenesis GO:0001745 249 0.051
embryonic pattern specification GO:0009880 174 0.050
response to hydrogen peroxide GO:0042542 11 0.050
morphogenesis of an epithelium GO:0002009 276 0.048
regulation of behavior GO:0050795 75 0.048
negative regulation of cellular component organization GO:0051129 108 0.046
negative regulation of signal transduction GO:0009968 206 0.046
centrosome organization GO:0051297 163 0.045
organonitrogen compound metabolic process GO:1901564 318 0.044
immune response activating signal transduction GO:0002757 2 0.044
primary amino compound biosynthetic process GO:1901162 2 0.044
gliogenesis GO:0042063 80 0.044
regulation of immune system process GO:0002682 176 0.043
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.043
phagocytosis GO:0006909 215 0.042
activation of innate immune response GO:0002218 4 0.042
endocytosis GO:0006897 310 0.042
organonitrogen compound biosynthetic process GO:1901566 117 0.042
immune response regulating signaling pathway GO:0002764 2 0.041
amino sugar catabolic process GO:0046348 3 0.041
aminoglycan biosynthetic process GO:0006023 11 0.041
tyrosine metabolic process GO:0006570 1 0.040
response to other organism GO:0051707 293 0.040
regulation of intracellular signal transduction GO:1902531 236 0.039
defense response GO:0006952 300 0.038
response to radiation GO:0009314 155 0.036
camera type eye development GO:0043010 4 0.036
innate immune response GO:0045087 144 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.034
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.034
multi organism behavior GO:0051705 175 0.033
response to abiotic stimulus GO:0009628 341 0.033
single organism biosynthetic process GO:0044711 206 0.033
body morphogenesis GO:0010171 2 0.033
negative regulation of signaling GO:0023057 219 0.032
regulation of defense response GO:0031347 102 0.032
histolysis GO:0007559 102 0.032
negative regulation of cellular metabolic process GO:0031324 382 0.031
negative regulation of cell communication GO:0010648 223 0.031
oxoacid metabolic process GO:0043436 103 0.031
regulation of cell cycle GO:0051726 291 0.030
chitin based cuticle sclerotization GO:0007593 19 0.030
hippo signaling GO:0035329 20 0.030
extracellular matrix organization GO:0030198 32 0.030
multicellular organismal reproductive behavior GO:0033057 110 0.030
organic substance catabolic process GO:1901575 308 0.029
protein modification process GO:0036211 438 0.029
negative regulation of multicellular organismal process GO:0051241 142 0.028
negative regulation of cell development GO:0010721 62 0.028
courtship behavior GO:0007619 68 0.028
nuclear division GO:0000280 332 0.028
cuticle pigmentation GO:0048067 22 0.028
multi organism reproductive behavior GO:0044705 121 0.028
single organism catabolic process GO:0044712 228 0.027
cation transport GO:0006812 110 0.027
organic cyclic compound catabolic process GO:1901361 168 0.027
anatomical structure homeostasis GO:0060249 97 0.026
response to external biotic stimulus GO:0043207 293 0.026
regulation of catalytic activity GO:0050790 185 0.026
positive regulation of gene expression GO:0010628 290 0.026
programmed cell death GO:0012501 257 0.026
embryonic morphogenesis GO:0048598 206 0.026
positive regulation of developmental process GO:0051094 143 0.025
response to biotic stimulus GO:0009607 294 0.025
homeostatic process GO:0042592 199 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
response to reactive oxygen species GO:0000302 24 0.025
response to alcohol GO:0097305 95 0.024
cellular amide metabolic process GO:0043603 80 0.024
gland morphogenesis GO:0022612 145 0.024
branching involved in open tracheal system development GO:0060446 45 0.024
innate immune response activating signal transduction GO:0002758 2 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.023
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.023
neurological system process GO:0050877 358 0.023
axon development GO:0061564 297 0.023
organic acid metabolic process GO:0006082 103 0.023
maintenance of location GO:0051235 73 0.023
developmental programmed cell death GO:0010623 138 0.023
malpighian tubule morphogenesis GO:0007443 44 0.022
blastoderm segmentation GO:0007350 159 0.022
catecholamine biosynthetic process GO:0042423 3 0.022
response to hexose GO:0009746 3 0.022
negative regulation of cellular biosynthetic process GO:0031327 277 0.022
response to nitrogen compound GO:1901698 90 0.022
regulation of nervous system development GO:0051960 248 0.022
multi multicellular organism process GO:0044706 123 0.022
cellular protein modification process GO:0006464 438 0.021
spindle organization GO:0007051 253 0.021
central nervous system development GO:0007417 201 0.021
neural precursor cell proliferation GO:0061351 75 0.021
tissue death GO:0016271 102 0.021
neuron projection guidance GO:0097485 241 0.021
positive regulation of immune response GO:0050778 63 0.021
synapse assembly GO:0007416 143 0.021
aromatic amino acid family metabolic process GO:0009072 3 0.021
skin development GO:0043588 65 0.020
aminoglycan metabolic process GO:0006022 18 0.020
dorsal trunk growth open tracheal system GO:0035001 7 0.020
notch signaling pathway GO:0007219 120 0.020
cellular response to hormone stimulus GO:0032870 44 0.020
regulation of response to stress GO:0080134 200 0.020
forebrain development GO:0030900 2 0.020
salivary gland morphogenesis GO:0007435 145 0.020
response to organonitrogen compound GO:0010243 75 0.020
eye development GO:0001654 323 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
regulation of locomotion GO:0040012 42 0.019
organelle fission GO:0048285 340 0.019
phenol containing compound metabolic process GO:0018958 57 0.019
salivary gland histolysis GO:0035070 88 0.019
regulation of innate immune response GO:0045088 71 0.018
gene silencing GO:0016458 138 0.018
regionalization GO:0003002 416 0.018
memory GO:0007613 94 0.018
regulation of developmental growth GO:0048638 174 0.018
thermotaxis GO:0043052 16 0.018
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.018
connective tissue development GO:0061448 3 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
centrosome duplication GO:0051298 121 0.018
response to lipopolysaccharide GO:0032496 4 0.018
regulation of molecular function GO:0065009 217 0.018
positive regulation of cell death GO:0010942 69 0.018
cellular response to endogenous stimulus GO:0071495 80 0.018
negative regulation of homeostatic process GO:0032845 2 0.018
cellular response to nitrogen compound GO:1901699 51 0.017
cellular response to peptide hormone stimulus GO:0071375 28 0.017
salivary gland development GO:0007431 162 0.017
dorsal ventral axis specification GO:0009950 66 0.017
regulation of immune response GO:0050776 118 0.017
dna endoreduplication GO:0042023 22 0.017
tube morphogenesis GO:0035239 191 0.017
fluid transport GO:0042044 19 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
protein maturation GO:0051604 71 0.017
reproductive behavior GO:0019098 122 0.016
amino sugar biosynthetic process GO:0046349 5 0.016
antimicrobial humoral response GO:0019730 99 0.016
regulation of transferase activity GO:0051338 58 0.016
long term memory GO:0007616 62 0.016
phosphorylation GO:0016310 294 0.016
anterior posterior pattern specification GO:0009952 136 0.016
torso signaling pathway GO:0008293 21 0.016
ion transport GO:0006811 145 0.016
regulation of neurogenesis GO:0050767 158 0.016
hindbrain development GO:0030902 2 0.016
cellular response to organonitrogen compound GO:0071417 36 0.016
dopamine biosynthetic process from tyrosine GO:0006585 1 0.016
microtubule organizing center organization GO:0031023 168 0.016
protein phosphorylation GO:0006468 169 0.015
response to oxidative stress GO:0006979 86 0.015
segmentation GO:0035282 207 0.015
cellular response to insulin stimulus GO:0032869 28 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
rna processing GO:0006396 147 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
regulation of gene silencing GO:0060968 63 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
centrosome cycle GO:0007098 137 0.015
response to peptide hormone GO:0043434 29 0.015
spindle assembly GO:0051225 80 0.015
regulation of neural precursor cell proliferation GO:2000177 35 0.015
positive regulation of developmental growth GO:0048639 62 0.015
ion transmembrane transport GO:0034220 122 0.015
carbohydrate derivative biosynthetic process GO:1901137 85 0.015
small molecule metabolic process GO:0044281 305 0.015
heterocycle catabolic process GO:0046700 166 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
androgen metabolic process GO:0008209 1 0.014
transcription from rna polymerase ii promoter GO:0006366 368 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
positive regulation of cell communication GO:0010647 250 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
negative regulation of catalytic activity GO:0043086 42 0.014
cellular response to organic substance GO:0071310 132 0.014
instar larval development GO:0002168 55 0.014
response to wounding GO:0009611 94 0.014
metal ion transport GO:0030001 74 0.014
compound eye photoreceptor fate commitment GO:0001752 36 0.014
molting cycle chitin based cuticle GO:0007591 56 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
lipid storage GO:0019915 38 0.014
defense response to bacterium GO:0042742 178 0.014
response to organic cyclic compound GO:0014070 89 0.014
steroid catabolic process GO:0006706 1 0.014
response to organophosphorus GO:0046683 2 0.014
mitotic nuclear division GO:0007067 213 0.014
regulation of extracellular matrix disassembly GO:0010715 1 0.014
sensory organ morphogenesis GO:0090596 260 0.014
primary amino compound metabolic process GO:1901160 2 0.014
regulation of phosphorylation GO:0042325 147 0.014
regulation of developmental pigmentation GO:0048070 24 0.014
catechol containing compound biosynthetic process GO:0009713 3 0.013
response to calcium ion GO:0051592 1 0.013
catabolic process GO:0009056 409 0.013
protein processing GO:0016485 68 0.013
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.013
defense response to other organism GO:0098542 225 0.013
mitotic spindle organization GO:0007052 220 0.013
camera type eye morphogenesis GO:0048593 2 0.013
autophagic cell death GO:0048102 83 0.013
pattern recognition receptor signaling pathway GO:0002221 2 0.013
cognition GO:0050890 141 0.013
axonogenesis GO:0007409 290 0.013
developmental growth involved in morphogenesis GO:0060560 65 0.013
secondary metabolic process GO:0019748 75 0.013
hormone catabolic process GO:0042447 3 0.013
actin cytoskeleton organization GO:0030036 206 0.013
regulation of response to biotic stimulus GO:0002831 63 0.013
eye morphogenesis GO:0048592 260 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
organelle localization GO:0051640 148 0.013
response to bacterium GO:0009617 198 0.012
response to mechanical stimulus GO:0009612 28 0.012
cell migration GO:0016477 238 0.012
embryonic axis specification GO:0000578 107 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
protein transport GO:0015031 155 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
localization of cell GO:0051674 257 0.012
response to carbohydrate GO:0009743 15 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of protein modification process GO:0031399 112 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
molting cycle GO:0042303 56 0.012
retina development in camera type eye GO:0060041 4 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
epithelial cell migration GO:0010631 148 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
response to inorganic substance GO:0010035 44 0.012
wound healing spreading of epidermal cells GO:0035313 1 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
apoptotic process GO:0006915 159 0.012
glucosamine containing compound catabolic process GO:1901072 3 0.012
cell death GO:0008219 279 0.012
carbohydrate metabolic process GO:0005975 82 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
glial cell differentiation GO:0010001 35 0.011
establishment of protein localization GO:0045184 163 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
dopamine biosynthetic process GO:0042416 3 0.011
regulation of cuticle pigmentation GO:0048079 16 0.011
regulation of antimicrobial humoral response GO:0002759 50 0.011
response to temperature stimulus GO:0009266 106 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
detection of stimulus GO:0051606 156 0.011
negative regulation of notch signaling pathway GO:0045746 41 0.011
positive regulation of cell motility GO:2000147 3 0.011
response to light stimulus GO:0009416 124 0.011
indole containing compound metabolic process GO:0042430 5 0.011
cell division GO:0051301 248 0.011
negative regulation of behavior GO:0048521 8 0.011
regulation of hippo signaling GO:0035330 14 0.011
morphogenesis of a branching structure GO:0001763 45 0.011
response to metal ion GO:0010038 23 0.011
positive regulation of epithelial cell differentiation GO:0030858 1 0.011
negative regulation of defense response GO:0031348 35 0.011
cholesterol transport GO:0030301 2 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
synaptic transmission GO:0007268 288 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
cell proliferation GO:0008283 299 0.010
protein secretion GO:0009306 45 0.010
nucleotide metabolic process GO:0009117 161 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
neuronal action potential GO:0019228 10 0.010
death GO:0016265 284 0.010
response to insulin GO:0032868 29 0.010
rhythmic behavior GO:0007622 76 0.010
ras protein signal transduction GO:0007265 88 0.010
regulation of protein metabolic process GO:0051246 256 0.010
brain development GO:0007420 120 0.010
response to ketone GO:1901654 34 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
cellular response to peptide GO:1901653 28 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010

obst-A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
disease of anatomical entity DOID:7 0 0.020
organ system cancer DOID:0050686 0 0.018
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.011