Drosophila melanogaster

105 known processes

Su(var)3-3 (Dmel_CG17149)

Suppressor of variegation 3-3

(Aliases: Lsd1,SU(VAR)3-3,dLsd1,Dmel\LSD1,Dmel/HDM,Su-var(3)3,CG17149,Dmel\CG17149,Dmel/LSD1,Hdm,Suvar(3)3)

Su(var)3-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 147 0.990
dna conformation change GO:0071103 105 0.922
histone modification GO:0016570 106 0.897
mrna metabolic process GO:0016071 124 0.833
chromosome organization GO:0051276 360 0.818
spermatogenesis GO:0007283 200 0.806
positive regulation of macromolecule metabolic process GO:0010604 405 0.751
dna packaging GO:0006323 91 0.727
regulation of cell differentiation GO:0045595 302 0.718
negative regulation of gene expression GO:0010629 387 0.686
positive regulation of cellular biosynthetic process GO:0031328 316 0.651
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.643
covalent chromatin modification GO:0016569 106 0.638
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.634
ovarian follicle cell development GO:0030707 248 0.616
chromatin organization GO:0006325 207 0.601
negative regulation of rna biosynthetic process GO:1902679 240 0.594
mrna processing GO:0006397 104 0.588
regionalization GO:0003002 416 0.570
methylation GO:0032259 47 0.555
protein acetylation GO:0006473 39 0.551
negative regulation of nucleic acid templated transcription GO:1903507 240 0.536
negative regulation of cellular biosynthetic process GO:0031327 277 0.532
positive regulation of biosynthetic process GO:0009891 316 0.528
internal protein amino acid acetylation GO:0006475 38 0.511
negative regulation of cellular metabolic process GO:0031324 382 0.510
rna splicing GO:0008380 83 0.506
positive regulation of rna metabolic process GO:0051254 271 0.475
chromatin assembly or disassembly GO:0006333 52 0.460
transcription from rna polymerase ii promoter GO:0006366 368 0.439
germ line stem cell maintenance GO:0030718 50 0.419
male gamete generation GO:0048232 201 0.417
stem cell development GO:0048864 79 0.407
gene silencing GO:0016458 138 0.391
chromosome condensation GO:0030261 41 0.384
cellular protein modification process GO:0006464 438 0.366
peptidyl lysine modification GO:0018205 57 0.356
positive regulation of cellular protein metabolic process GO:0032270 118 0.349
peptidyl lysine acetylation GO:0018394 39 0.346
heterochromatin organization GO:0070828 25 0.342
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.332
regulation of gene expression epigenetic GO:0040029 128 0.327
internal peptidyl lysine acetylation GO:0018393 38 0.324
negative regulation of chromatin silencing GO:0031936 9 0.321
cell motility GO:0048870 251 0.312
positive regulation of gene expression GO:0010628 290 0.293
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.291
histone acetylation GO:0016573 38 0.289
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.265
negative regulation of gene expression epigenetic GO:0045814 77 0.264
epithelial cell development GO:0002064 274 0.262
positive regulation of transcription dna templated GO:0045893 266 0.258
reproductive structure development GO:0048608 74 0.252
protein acylation GO:0043543 42 0.245
peptidyl amino acid modification GO:0018193 105 0.237
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.226
eggshell formation GO:0030703 105 0.219
regulation of protein metabolic process GO:0051246 256 0.218
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.216
regulation of gene silencing GO:0060968 63 0.214
negative regulation of biosynthetic process GO:0009890 277 0.211
stem cell differentiation GO:0048863 117 0.210
epithelium migration GO:0090132 148 0.201
cell proliferation GO:0008283 299 0.198
regulation of cell proliferation GO:0042127 163 0.197
positive regulation of nucleic acid templated transcription GO:1903508 266 0.197
dna metabolic process GO:0006259 227 0.187
positive regulation of rna biosynthetic process GO:1902680 266 0.185
chromatin silencing GO:0006342 76 0.183
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.178
protein modification process GO:0036211 438 0.173
cellular macromolecular complex assembly GO:0034622 153 0.166
cell migration GO:0016477 238 0.158
axon development GO:0061564 297 0.158
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.146
epithelial cell differentiation GO:0030855 322 0.141
appendage morphogenesis GO:0035107 397 0.137
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.131
embryo development ending in birth or egg hatching GO:0009792 152 0.131
tissue migration GO:0090130 155 0.131
reproductive system development GO:0061458 74 0.129
columnar cuboidal epithelial cell development GO:0002066 249 0.119
endocytosis GO:0006897 310 0.119
regulation of chromatin silencing GO:0031935 36 0.117
gonad development GO:0008406 50 0.116
histone h4 k16 acetylation GO:0043984 4 0.112
protein dna complex subunit organization GO:0071824 86 0.107
defense response to other organism GO:0098542 225 0.107
dna alkylation GO:0006305 4 0.105
stem cell maintenance GO:0019827 67 0.100
negative regulation of cell differentiation GO:0045596 143 0.093
anterior posterior pattern specification GO:0009952 136 0.093
negative regulation of rna metabolic process GO:0051253 251 0.090
anterior posterior axis specification GO:0009948 109 0.089
nuclear envelope organization GO:0006998 7 0.087
eggshell chorion assembly GO:0007306 66 0.085
macromolecular complex assembly GO:0065003 256 0.085
nucleocytoplasmic transport GO:0006913 72 0.081
post embryonic appendage morphogenesis GO:0035120 385 0.081
regulation of transcription by chromatin organization GO:0034401 3 0.080
regulation of cellular localization GO:0060341 136 0.078
rna processing GO:0006396 147 0.078
defense response GO:0006952 300 0.077
epithelial cell migration GO:0010631 148 0.077
spermatid differentiation GO:0048515 114 0.076
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.074
dna methylation GO:0006306 4 0.073
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.073
negative regulation of developmental process GO:0051093 201 0.072
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.072
regulation of cellular protein metabolic process GO:0032268 243 0.070
larval development GO:0002164 104 0.070
regulation of cellular component biogenesis GO:0044087 201 0.070
embryonic development via the syncytial blastoderm GO:0001700 148 0.067
regulation of rna splicing GO:0043484 69 0.065
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.063
regulation of mrna metabolic process GO:1903311 72 0.063
stem cell division GO:0017145 69 0.063
regulation of mrna processing GO:0050684 71 0.063
germarium derived egg chamber formation GO:0007293 101 0.062
dorsal appendage formation GO:0046843 47 0.061
dna methylation or demethylation GO:0044728 4 0.061
vesicle mediated transport GO:0016192 381 0.060
oocyte differentiation GO:0009994 145 0.059
histone h4 acetylation GO:0043967 13 0.057
embryonic axis specification GO:0000578 107 0.057
rna splicing via transesterification reactions GO:0000375 73 0.054
regulation of cell development GO:0060284 215 0.054
cell cell signaling involved in cell fate commitment GO:0045168 210 0.053
regulation of neurogenesis GO:0050767 158 0.052
cell death GO:0008219 279 0.052
protein alkylation GO:0008213 43 0.051
regulation of translation GO:0006417 56 0.050
regulation of chromatin organization GO:1902275 32 0.050
imaginal disc derived appendage development GO:0048737 399 0.048
cell fate specification GO:0001708 71 0.047
mrna splicing via spliceosome GO:0000398 73 0.046
regulation of chromatin modification GO:1903308 28 0.046
alternative mrna splicing via spliceosome GO:0000380 60 0.045
positive regulation of response to stimulus GO:0048584 323 0.044
appendage development GO:0048736 401 0.043
translation GO:0006412 69 0.043
negative regulation of signaling GO:0023057 219 0.043
regulation of growth GO:0040008 233 0.042
growth GO:0040007 359 0.041
blastoderm segmentation GO:0007350 159 0.039
response to biotic stimulus GO:0009607 294 0.039
chorion containing eggshell formation GO:0007304 105 0.039
immune system process GO:0002376 347 0.037
cellular amine metabolic process GO:0044106 12 0.037
genitalia development GO:0048806 26 0.034
compound eye cone cell fate commitment GO:0042676 5 0.034
asymmetric stem cell division GO:0098722 49 0.034
negative regulation of response to stimulus GO:0048585 258 0.034
positive regulation of signal transduction GO:0009967 223 0.033
cellular response to dna damage stimulus GO:0006974 223 0.033
mitotic nuclear division GO:0007067 213 0.033
regulation of multicellular organismal development GO:2000026 414 0.032
developmental growth GO:0048589 280 0.031
chromatin remodeling GO:0006338 72 0.031
dna templated transcription initiation GO:0006352 25 0.030
axis specification GO:0009798 167 0.030
lateral inhibition GO:0046331 206 0.030
oocyte maturation GO:0001556 3 0.030
cellular component assembly involved in morphogenesis GO:0010927 151 0.030
axon guidance GO:0007411 233 0.029
rna localization GO:0006403 115 0.029
regulation of cellular ketone metabolic process GO:0010565 3 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
response to external biotic stimulus GO:0043207 293 0.028
female germ line cyst formation GO:0048135 42 0.028
germ line stem cell division GO:0042078 25 0.027
compound eye development GO:0048749 307 0.027
regulation of meiosis GO:0040020 3 0.027
wing disc morphogenesis GO:0007472 344 0.027
mitotic chromosome condensation GO:0007076 22 0.027
histone methylation GO:0016571 40 0.027
open tracheal system development GO:0007424 204 0.026
regulation of nervous system development GO:0051960 248 0.025
anterior posterior axis specification embryo GO:0008595 103 0.025
defense response to bacterium GO:0042742 178 0.025
negative regulation of signal transduction GO:0009968 206 0.025
posttranscriptional regulation of gene expression GO:0010608 145 0.025
positive regulation of translation GO:0045727 12 0.024
organic substance transport GO:0071702 257 0.024
development of primary sexual characteristics GO:0045137 50 0.024
taxis GO:0042330 304 0.024
positive regulation of protein metabolic process GO:0051247 128 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.023
nucleosome organization GO:0034728 59 0.022
regulation of neuron differentiation GO:0045664 103 0.022
cognition GO:0050890 141 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
cellular macromolecule localization GO:0070727 220 0.022
positive regulation of cell communication GO:0010647 250 0.021
neuron projection guidance GO:0097485 241 0.021
macromolecule catabolic process GO:0009057 161 0.021
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.020
localization of cell GO:0051674 257 0.020
positive regulation of gene expression epigenetic GO:0045815 16 0.020
imaginal disc derived wing vein specification GO:0007474 48 0.019
developmental maturation GO:0021700 172 0.019
dsrna fragmentation GO:0031050 15 0.019
intracellular signal transduction GO:0035556 300 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
embryonic pattern specification GO:0009880 174 0.018
multicellular organismal aging GO:0010259 140 0.018
negative regulation of cell communication GO:0010648 223 0.018
heterocycle catabolic process GO:0046700 166 0.017
pole plasm mrna localization GO:0019094 49 0.017
protein complex biogenesis GO:0070271 201 0.017
posttranscriptional gene silencing GO:0016441 46 0.017
macromolecule methylation GO:0043414 45 0.017
immune system development GO:0002520 57 0.017
oocyte development GO:0048599 124 0.016
amine metabolic process GO:0009308 12 0.016
response to other organism GO:0051707 293 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
regulation of mrna splicing via spliceosome GO:0048024 64 0.016
tissue morphogenesis GO:0048729 297 0.015
centrosome cycle GO:0007098 137 0.015
ribonucleoprotein complex assembly GO:0022618 23 0.015
positive regulation of signaling GO:0023056 243 0.015
apoptotic process GO:0006915 159 0.015
organic substance catabolic process GO:1901575 308 0.014
cellular ketone metabolic process GO:0042180 24 0.014
regulation of apoptotic process GO:0042981 130 0.014
nucleus organization GO:0006997 45 0.014
negative regulation of neurotransmitter secretion GO:0046929 2 0.014
protein ubiquitination GO:0016567 70 0.013
protein dna complex assembly GO:0065004 63 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
cellular response to organic cyclic compound GO:0071407 32 0.013
dendrite development GO:0016358 204 0.013
sex differentiation GO:0007548 81 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
regulation of response to external stimulus GO:0032101 115 0.013
regulation of developmental growth GO:0048638 174 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
dna integrity checkpoint GO:0031570 81 0.012
body morphogenesis GO:0010171 2 0.012
germarium derived female germ line cyst formation GO:0030727 42 0.012
single organism catabolic process GO:0044712 228 0.012
oocyte axis specification GO:0007309 108 0.012
protein methylation GO:0006479 43 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
regulation of cell death GO:0010941 173 0.012
histone mrna metabolic process GO:0008334 8 0.012
germ line cyst formation GO:0048134 44 0.012
nuclear transport GO:0051169 72 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
negative regulation of cell death GO:0060548 81 0.012
regulation of cell cycle GO:0051726 291 0.012
segmentation GO:0035282 207 0.011
regulation of transport GO:0051049 181 0.011
tripartite regional subdivision GO:0007351 103 0.011
regulation of protein modification process GO:0031399 112 0.011
histone lysine methylation GO:0034968 32 0.011
phosphorylation GO:0016310 294 0.011
production of sirna involved in rna interference GO:0030422 11 0.011
nuclear import GO:0051170 51 0.011
cytoplasm organization GO:0007028 64 0.011
cell maturation GO:0048469 144 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
morphogenesis of follicular epithelium GO:0016333 36 0.011
salivary gland development GO:0007431 162 0.010
regulation of apoptotic signaling pathway GO:2001233 10 0.010
determination of adult lifespan GO:0008340 137 0.010
dna modification GO:0006304 5 0.010
negative regulation of transcription factor import into nucleus GO:0042992 4 0.010
regulation of histone modification GO:0031056 20 0.010
ribonucleoprotein complex biogenesis GO:0022613 31 0.010
eye development GO:0001654 323 0.010

Su(var)3-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020