Drosophila melanogaster

19 known processes

Pglym78 (Dmel_CG1721)

Phosphoglyceromutase

(Aliases: Pglym,Dmel\CG1721,PGAM,PGLYM,CG1721)

Pglym78 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myoblast fusion GO:0007520 43 0.999
syncytium formation GO:0006949 43 0.998
syncytium formation by plasma membrane fusion GO:0000768 43 0.983
somatic muscle development GO:0007525 66 0.941
myotube differentiation GO:0014902 46 0.918
muscle structure development GO:0061061 224 0.807
muscle cell differentiation GO:0042692 103 0.780
striated muscle cell differentiation GO:0051146 90 0.523
determination of adult lifespan GO:0008340 137 0.473
purine nucleoside metabolic process GO:0042278 127 0.330
nad metabolic process GO:0019674 1 0.314
oxoacid metabolic process GO:0043436 103 0.237
Human Yeast Mouse
negative regulation of gene expression GO:0010629 387 0.209
nucleoside metabolic process GO:0009116 127 0.198
ribonucleoside triphosphate metabolic process GO:0009199 119 0.189
larval development GO:0002164 104 0.188
organic substance catabolic process GO:1901575 308 0.183
Human Yeast Mouse
catabolic process GO:0009056 409 0.182
Human Yeast Mouse
actin filament based process GO:0030029 220 0.181
small molecule metabolic process GO:0044281 305 0.180
Human Yeast Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.175
single organism catabolic process GO:0044712 228 0.161
Human Yeast Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.155
ribose phosphate metabolic process GO:0019693 145 0.154
glycosyl compound metabolic process GO:1901657 127 0.150
atp biosynthetic process GO:0006754 2 0.149
nucleotide metabolic process GO:0009117 161 0.147
ribonucleoside biosynthetic process GO:0042455 3 0.145
purine nucleoside triphosphate metabolic process GO:0009144 119 0.130
carboxylic acid metabolic process GO:0019752 92 0.128
Human Yeast Mouse
glycolytic process GO:0006096 6 0.120
Human Yeast Mouse
cellular component assembly involved in morphogenesis GO:0010927 151 0.120
organonitrogen compound metabolic process GO:1901564 318 0.119
regulation of anatomical structure morphogenesis GO:0022603 242 0.118
endocytosis GO:0006897 310 0.118
developmental growth GO:0048589 280 0.116
regulation of growth GO:0040008 233 0.111
negative regulation of cellular metabolic process GO:0031324 382 0.105
cell cell signaling involved in cell fate commitment GO:0045168 210 0.104
pyruvate metabolic process GO:0006090 7 0.101
Human Yeast Mouse
response to oxidative stress GO:0006979 86 0.099
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.098
spermatogenesis GO:0007283 200 0.098
Rat
male gamete generation GO:0048232 201 0.096
Rat
nucleobase containing small molecule metabolic process GO:0055086 174 0.095
regulation of programmed cell death GO:0043067 152 0.094
ribose phosphate biosynthetic process GO:0046390 28 0.085
purine ribonucleoside metabolic process GO:0046128 127 0.084
purine nucleotide metabolic process GO:0006163 146 0.083
nucleoside phosphate biosynthetic process GO:1901293 34 0.081
ribonucleoside metabolic process GO:0009119 127 0.081
negative regulation of response to stimulus GO:0048585 258 0.081
posttranscriptional regulation of gene expression GO:0010608 145 0.080
cellular response to chemical stimulus GO:0070887 199 0.078
growth GO:0040007 359 0.076
aging GO:0007568 143 0.074
carbohydrate catabolic process GO:0016052 7 0.072
Human Yeast Mouse
lipid storage GO:0019915 38 0.071
organophosphate metabolic process GO:0019637 195 0.071
regulation of syncytium formation by plasma membrane fusion GO:0060142 6 0.071
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.070
nucleoside triphosphate metabolic process GO:0009141 120 0.067
multicellular organismal aging GO:0010259 140 0.067
ribonucleotide metabolic process GO:0009259 145 0.066
regulation of multicellular organismal development GO:2000026 414 0.064
purine ribonucleotide metabolic process GO:0009150 145 0.063
immune response GO:0006955 246 0.063
lipid localization GO:0010876 54 0.062
positive regulation of growth GO:0045927 75 0.061
nucleoside biosynthetic process GO:0009163 3 0.061
regulation of cell development GO:0060284 215 0.061
negative regulation of biosynthetic process GO:0009890 277 0.061
carbohydrate derivative metabolic process GO:1901135 217 0.058
negative regulation of developmental process GO:0051093 201 0.057
negative regulation of translation GO:0017148 28 0.057
purine nucleoside biosynthetic process GO:0042451 3 0.056
regulation of apoptotic process GO:0042981 130 0.055
atp metabolic process GO:0046034 49 0.054
cell death GO:0008219 279 0.054
regulation of myotube differentiation GO:0010830 6 0.053
cellular modified amino acid metabolic process GO:0006575 45 0.053
anatomical structure homeostasis GO:0060249 97 0.052
purine containing compound metabolic process GO:0072521 155 0.051
regulation of cell proliferation GO:0042127 163 0.051
regulation of cell differentiation GO:0045595 302 0.050
cell motility GO:0048870 251 0.050
multi multicellular organism process GO:0044706 123 0.050
innate immune response GO:0045087 144 0.048
embryo development ending in birth or egg hatching GO:0009792 152 0.047
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.047
generation of precursor metabolites and energy GO:0006091 42 0.046
Human Yeast Mouse
organophosphate biosynthetic process GO:0090407 46 0.046
lateral inhibition GO:0046331 206 0.044
spermatid differentiation GO:0048515 114 0.044
cell aging GO:0007569 2 0.043
localization of cell GO:0051674 257 0.043
regulation of cell morphogenesis GO:0022604 163 0.042
regulation of developmental growth GO:0048638 174 0.042
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.042
regulation of cell shape GO:0008360 113 0.041
imaginal disc derived wing morphogenesis GO:0007476 337 0.040
response to organophosphorus GO:0046683 2 0.039
organic acid metabolic process GO:0006082 103 0.039
Human Yeast Mouse
regulation of nervous system development GO:0051960 248 0.038
striated muscle cell development GO:0055002 50 0.038
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.038
programmed cell death GO:0012501 257 0.038
regulation of cell death GO:0010941 173 0.038
cellular ketone metabolic process GO:0042180 24 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.037
substrate adhesion dependent cell spreading GO:0034446 2 0.037
gland development GO:0048732 191 0.037
response to hypoxia GO:0001666 53 0.036
nucleoside phosphate metabolic process GO:0006753 162 0.036
response to temperature stimulus GO:0009266 106 0.036
negative regulation of multicellular organismal process GO:0051241 142 0.036
spermatid development GO:0007286 98 0.035
response to abiotic stimulus GO:0009628 341 0.035
actin filament organization GO:0007015 126 0.035
cellular protein complex assembly GO:0043623 71 0.034
defense response GO:0006952 300 0.034
striated muscle myosin thick filament assembly GO:0071688 3 0.034
appendage development GO:0048736 401 0.033
multi organism behavior GO:0051705 175 0.033
biological adhesion GO:0022610 138 0.033
negative regulation of cellular component organization GO:0051129 108 0.033
regulation of intracellular signal transduction GO:1902531 236 0.032
single organism intracellular transport GO:1902582 207 0.032
cellular catabolic process GO:0044248 372 0.032
ribonucleoside catabolic process GO:0042454 112 0.031
organonitrogen compound biosynthetic process GO:1901566 117 0.031
response to heat GO:0009408 63 0.030
response to organic substance GO:0010033 284 0.030
organophosphate catabolic process GO:0046434 112 0.030
reactive oxygen species metabolic process GO:0072593 22 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.029
protein complex biogenesis GO:0070271 201 0.029
positive regulation of cell death GO:0010942 69 0.029
negative regulation of cell differentiation GO:0045596 143 0.029
nucleoside catabolic process GO:0009164 112 0.028
actin cytoskeleton organization GO:0030036 206 0.028
purine ribonucleotide catabolic process GO:0009154 109 0.028
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.028
regulation of response to stress GO:0080134 200 0.028
tricarboxylic acid metabolic process GO:0072350 1 0.028
death GO:0016265 284 0.028
regulation of imaginal disc derived wing size GO:0044719 20 0.028
negative regulation of cellular protein metabolic process GO:0032269 85 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
ribonucleotide biosynthetic process GO:0009260 28 0.027
positive regulation of developmental process GO:0051094 143 0.027
regulation of protein metabolic process GO:0051246 256 0.027
regulation of organ morphogenesis GO:2000027 78 0.026
regulation of cellular protein metabolic process GO:0032268 243 0.026
response to external biotic stimulus GO:0043207 293 0.026
maintenance of location GO:0051235 73 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
purine nucleotide catabolic process GO:0006195 109 0.026
nucleoside monophosphate biosynthetic process GO:0009124 4 0.026
phosphorylation GO:0016310 294 0.025
carbohydrate derivative catabolic process GO:1901136 118 0.025
mesoderm development GO:0007498 78 0.025
reproductive structure development GO:0048608 74 0.025
cellular protein modification process GO:0006464 438 0.024
response to monosaccharide GO:0034284 4 0.024
stem cell differentiation GO:0048863 117 0.024
myofibril assembly GO:0030239 36 0.024
response to endogenous stimulus GO:0009719 119 0.024
nucleotide catabolic process GO:0009166 109 0.023
single organism carbohydrate catabolic process GO:0044724 7 0.023
Human Yeast Mouse
sex differentiation GO:0007548 81 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
proteolysis GO:0006508 192 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
response to nitrogen compound GO:1901698 90 0.022
regulation of catabolic process GO:0009894 170 0.022
heterocycle catabolic process GO:0046700 166 0.022
intracellular signal transduction GO:0035556 300 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
positive regulation of signal transduction GO:0009967 223 0.021
purine ribonucleoside catabolic process GO:0046130 112 0.021
regulation of cellular catabolic process GO:0031329 157 0.021
organic substance transport GO:0071702 257 0.021
reproductive system development GO:0061458 74 0.021
response to oxygen containing compound GO:1901700 200 0.020
oxidation reduction process GO:0055114 123 0.020
regulation of neurogenesis GO:0050767 158 0.020
single organism biosynthetic process GO:0044711 206 0.020
Yeast Rat
response to inorganic substance GO:0010035 44 0.020
Rat
response to decreased oxygen levels GO:0036293 58 0.020
immune system process GO:0002376 347 0.020
positive regulation of molecular function GO:0044093 136 0.020
response to glucose GO:0009749 2 0.020
phagocytosis GO:0006909 215 0.019
reproductive behavior GO:0019098 122 0.019
response to oxygen levels GO:0070482 59 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
response to reactive oxygen species GO:0000302 24 0.019
cell migration GO:0016477 238 0.019
cellular carbohydrate catabolic process GO:0044275 2 0.019
regulation of catalytic activity GO:0050790 185 0.019
positive regulation of programmed cell death GO:0043068 62 0.019
defense response to bacterium GO:0042742 178 0.019
response to wounding GO:0009611 94 0.018
response to lithium ion GO:0010226 1 0.018
actomyosin structure organization GO:0031032 56 0.018
response to nutrient levels GO:0031667 114 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
positive regulation of developmental growth GO:0048639 62 0.018
cellular amino acid metabolic process GO:0006520 61 0.017
wound healing GO:0042060 75 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
thioester metabolic process GO:0035383 3 0.017
body morphogenesis GO:0010171 2 0.017
macromolecule catabolic process GO:0009057 161 0.017
small molecule biosynthetic process GO:0044283 37 0.017
immune response regulating signaling pathway GO:0002764 2 0.017
g protein coupled receptor signaling pathway GO:0007186 136 0.017
single organism carbohydrate metabolic process GO:0044723 72 0.017
Human Yeast Mouse Rat
nucleoside phosphate catabolic process GO:1901292 110 0.017
regulation of anatomical structure size GO:0090066 163 0.017
negative regulation of nervous system development GO:0051961 92 0.017
negative regulation of cell cycle GO:0045786 116 0.017
carbohydrate derivative biosynthetic process GO:1901137 85 0.017
purine nucleoside monophosphate metabolic process GO:0009126 50 0.017
vesicle mediated transport GO:0016192 381 0.017
nucleoside monophosphate metabolic process GO:0009123 52 0.017
monocarboxylic acid metabolic process GO:0032787 29 0.017
Human Yeast Mouse
glycosyl compound catabolic process GO:1901658 112 0.016
nucleotide biosynthetic process GO:0009165 34 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
negative regulation of signaling GO:0023057 219 0.016
cellular macromolecule localization GO:0070727 220 0.016
negative regulation of organelle organization GO:0010639 56 0.016
regulation of cell cycle GO:0051726 291 0.016
regulation of organelle organization GO:0033043 196 0.016
development of primary sexual characteristics GO:0045137 50 0.016
single organism behavior GO:0044708 391 0.016
negative regulation of cell communication GO:0010648 223 0.016
chromosome organization GO:0051276 360 0.016
cell adhesion GO:0007155 136 0.016
carbohydrate metabolic process GO:0005975 82 0.016
Human Yeast Mouse Rat
intracellular transport GO:0046907 228 0.016
salivary gland development GO:0007431 162 0.016
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.015
exocrine system development GO:0035272 162 0.015
central nervous system development GO:0007417 201 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
cell proliferation GO:0008283 299 0.015
purine ribonucleotide biosynthetic process GO:0009152 28 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
tube development GO:0035295 244 0.015
forebrain development GO:0030900 2 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
regulation of cellular component size GO:0032535 98 0.014
negative regulation of signal transduction GO:0009968 206 0.014
regulation of hydrolase activity GO:0051336 97 0.014
cardiocyte differentiation GO:0035051 29 0.014
taxis GO:0042330 304 0.014
appendage morphogenesis GO:0035107 397 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
peptidyl amino acid modification GO:0018193 105 0.014
cellular response to endogenous stimulus GO:0071495 80 0.013
cellular response to extracellular stimulus GO:0031668 64 0.013
chemotaxis GO:0006935 249 0.013
brain development GO:0007420 120 0.013
macromolecular complex assembly GO:0065003 256 0.013
positive regulation of apoptotic process GO:0043065 47 0.013
chaeta development GO:0022416 97 0.013
regulation of mrna processing GO:0050684 71 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
purine containing compound catabolic process GO:0072523 112 0.013
negative regulation of immune system process GO:0002683 50 0.013
response to organonitrogen compound GO:0010243 75 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
positive regulation of cell communication GO:0010647 250 0.013
larval somatic muscle development GO:0007526 19 0.013
regulation of notch signaling pathway GO:0008593 100 0.012
apoptotic process GO:0006915 159 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
negative regulation of immune response GO:0050777 39 0.012
protein maturation GO:0051604 71 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
spinal cord development GO:0021510 1 0.012
regulation of immune response GO:0050776 118 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
tube morphogenesis GO:0035239 191 0.012
aromatic compound catabolic process GO:0019439 166 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
glycosyl compound biosynthetic process GO:1901659 3 0.012
nucleoside triphosphate biosynthetic process GO:0009142 2 0.012
protein targeting to nucleus GO:0044744 51 0.011
purine nucleotide biosynthetic process GO:0006164 29 0.011
axonogenesis GO:0007409 290 0.011
multi organism reproductive behavior GO:0044705 121 0.011
protein modification process GO:0036211 438 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
ion transport GO:0006811 145 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
muscle cell migration GO:0014812 3 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
locomotory behavior GO:0007626 176 0.011
multicellular organism growth GO:0035264 46 0.011
camera type eye development GO:0043010 4 0.011
muscle cell development GO:0055001 50 0.011
epithelial cell differentiation GO:0030855 322 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
compound eye development GO:0048749 307 0.011
positive regulation of cell proliferation GO:0008284 47 0.010
regulation of myoblast fusion GO:1901739 6 0.010
regulation of localization GO:0032879 275 0.010
regionalization GO:0003002 416 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
regulation of purine nucleotide catabolic process GO:0033121 48 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
protein catabolic process GO:0030163 101 0.010
response to purine containing compound GO:0014074 12 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.010
axon development GO:0061564 297 0.010
organelle assembly GO:0070925 198 0.010
gtp metabolic process GO:0046039 72 0.010
atp catabolic process GO:0006200 38 0.010

Pglym78 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.026
disease of anatomical entity DOID:7 0 0.021
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.018