Drosophila melanogaster

62 known processes

Pp2A-29B (Dmel_CG17291)

Protein phosphatase 2A at 29B

(Aliases: Dmel\CG17291,CG13383,dPP2A A,A/PR65,Pp2A,PP2A,CG33297,PR65,PP2A-A,DPR65,CG17291,PP2A-29B)

Pp2A-29B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of organelle localization GO:0051656 122 0.982
mitotic cell cycle checkpoint GO:0007093 88 0.872
cellular response to dna damage stimulus GO:0006974 223 0.740
dna damage checkpoint GO:0000077 78 0.738
nuclear division GO:0000280 332 0.731
organelle fission GO:0048285 340 0.724
cell division GO:0051301 248 0.712
cell cycle checkpoint GO:0000075 95 0.711
embryo development ending in birth or egg hatching GO:0009792 152 0.703
synaptic transmission GO:0007268 288 0.698
negative regulation of cell cycle process GO:0010948 109 0.674
single organism cellular localization GO:1902580 180 0.653
establishment of localization in cell GO:0051649 402 0.531
protein localization GO:0008104 284 0.530
cellular protein localization GO:0034613 160 0.525
mitotic nuclear division GO:0007067 213 0.487
regulation of cell cycle GO:0051726 291 0.478
protein complex biogenesis GO:0070271 201 0.463
negative regulation of cell cycle phase transition GO:1901988 103 0.457
cellular macromolecular complex assembly GO:0034622 153 0.448
macromolecular complex assembly GO:0065003 256 0.414
dna integrity checkpoint GO:0031570 81 0.412
establishment of vesicle localization GO:0051650 51 0.394
regulation of receptor mediated endocytosis GO:0048259 9 0.393
mitotic g2 dna damage checkpoint GO:0007095 69 0.376
cytoskeleton dependent cytokinesis GO:0061640 81 0.375
mitotic dna integrity checkpoint GO:0044774 75 0.360
meiotic cell cycle GO:0051321 171 0.359
spindle assembly GO:0051225 80 0.355
cullin deneddylation GO:0010388 3 0.327
regulation of mitotic cell cycle phase transition GO:1901990 130 0.313
gliogenesis GO:0042063 80 0.303
cellular macromolecule localization GO:0070727 220 0.291
regulation of mitotic cell cycle GO:0007346 190 0.286
protein complex assembly GO:0006461 200 0.281
ion transport GO:0006811 145 0.266
regulation of cell cycle process GO:0010564 181 0.261
regulation of cell cycle phase transition GO:1901987 130 0.251
organic substance catabolic process GO:1901575 308 0.241
intracellular transport GO:0046907 228 0.241
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.235
mitotic spindle organization GO:0007052 220 0.231
death GO:0016265 284 0.227
mitotic cell cycle phase transition GO:0044772 138 0.226
spindle organization GO:0007051 253 0.222
dendrite development GO:0016358 204 0.219
axon development GO:0061564 297 0.214
cellular protein complex assembly GO:0043623 71 0.211
multicellular organismal aging GO:0010259 140 0.201
g2 dna damage checkpoint GO:0031572 69 0.201
mitotic g2 m transition checkpoint GO:0044818 70 0.200
axonogenesis GO:0007409 290 0.197
mitochondrion organization GO:0007005 65 0.197
maintenance of location GO:0051235 73 0.192
regulation of cellular component biogenesis GO:0044087 201 0.192
regulation of cellular localization GO:0060341 136 0.189
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.187
axon guidance GO:0007411 233 0.179
morphogenesis of embryonic epithelium GO:0016331 94 0.176
regulation of localization GO:0032879 275 0.176
synaptic vesicle transport GO:0048489 50 0.175
mitotic dna damage checkpoint GO:0044773 74 0.175
intracellular protein transport GO:0006886 104 0.172
vesicle localization GO:0051648 55 0.167
regulation of meiosis GO:0040020 3 0.166
maintenance of protein location in cell GO:0032507 26 0.163
protein localization to organelle GO:0033365 82 0.160
cell cycle phase transition GO:0044770 140 0.151
synaptic vesicle localization GO:0097479 53 0.148
establishment of synaptic vesicle localization GO:0097480 50 0.146
protein polymerization GO:0051258 42 0.146
programmed cell death GO:0012501 257 0.144
cell death GO:0008219 279 0.143
multicellular organismal reproductive behavior GO:0033057 110 0.141
cytoplasmic transport GO:0016482 130 0.137
lipid localization GO:0010876 54 0.136
regulation of transmembrane transport GO:0034762 27 0.133
asymmetric neuroblast division GO:0055059 33 0.131
aging GO:0007568 143 0.130
maintenance of protein location GO:0045185 28 0.130
single organism catabolic process GO:0044712 228 0.129
negative regulation of mitotic cell cycle GO:0045930 109 0.122
mitotic spindle checkpoint GO:0071174 11 0.119
determination of adult lifespan GO:0008340 137 0.118
proteolysis GO:0006508 192 0.116
glycosyl compound catabolic process GO:1901658 112 0.116
growth GO:0040007 359 0.115
protein modification process GO:0036211 438 0.113
positive regulation of macromolecule metabolic process GO:0010604 405 0.110
cellular catabolic process GO:0044248 372 0.108
embryonic development via the syncytial blastoderm GO:0001700 148 0.107
organic substance transport GO:0071702 257 0.106
positive regulation of developmental process GO:0051094 143 0.106
neuron recognition GO:0008038 101 0.105
brain development GO:0007420 120 0.100
neuroblast proliferation GO:0007405 74 0.098
dna repair GO:0006281 54 0.097
lateral inhibition GO:0046331 206 0.096
maintenance of location in cell GO:0051651 28 0.094
ribonucleoside catabolic process GO:0042454 112 0.093
chemical homeostasis GO:0048878 92 0.089
metal ion transport GO:0030001 74 0.087
establishment of mitotic spindle localization GO:0040001 17 0.085
membrane organization GO:0061024 112 0.085
establishment of protein localization to organelle GO:0072594 62 0.083
cell cell signaling involved in cell fate commitment GO:0045168 210 0.078
taxis GO:0042330 304 0.078
posttranscriptional regulation of gene expression GO:0010608 145 0.077
regulation of neurogenesis GO:0050767 158 0.076
regulation of protein catabolic process GO:0042176 55 0.076
protein phosphorylation GO:0006468 169 0.074
larval development GO:0002164 104 0.073
regulation of growth GO:0040008 233 0.073
organelle localization GO:0051640 148 0.071
reproductive system development GO:0061458 74 0.071
signal transduction by phosphorylation GO:0023014 107 0.071
negative regulation of phosphorus metabolic process GO:0010563 45 0.070
endocytosis GO:0006897 310 0.070
regulation of protein metabolic process GO:0051246 256 0.068
imaginal disc growth GO:0007446 37 0.068
actin filament based process GO:0030029 220 0.066
regulation of cell division GO:0051302 72 0.066
positive regulation of gene expression GO:0010628 290 0.065
ubiquitin dependent protein catabolic process GO:0006511 78 0.065
heterocycle catabolic process GO:0046700 166 0.065
positive regulation of cell communication GO:0010647 250 0.065
nucleoside catabolic process GO:0009164 112 0.063
protein import GO:0017038 55 0.062
vesicle mediated transport GO:0016192 381 0.062
establishment of protein localization GO:0045184 163 0.062
neuromuscular junction development GO:0007528 149 0.061
purine nucleotide catabolic process GO:0006195 109 0.058
response to bacterium GO:0009617 198 0.058
carbohydrate derivative catabolic process GO:1901136 118 0.055
regulation of catabolic process GO:0009894 170 0.054
cytokinesis GO:0000910 90 0.053
meiotic chromosome segregation GO:0045132 59 0.051
neuron projection extension GO:1990138 32 0.051
negative regulation of cell cycle GO:0045786 116 0.048
regulation of synapse organization GO:0050807 110 0.047
meiotic cytokinesis GO:0033206 33 0.046
intracellular protein transmembrane transport GO:0065002 4 0.045
response to light stimulus GO:0009416 124 0.045
sex differentiation GO:0007548 81 0.045
neuromuscular synaptic transmission GO:0007274 67 0.044
protein import into nucleus GO:0006606 51 0.043
meiotic nuclear division GO:0007126 151 0.042
positive regulation of transport GO:0051050 92 0.042
protein targeting GO:0006605 64 0.041
dendrite morphogenesis GO:0048813 199 0.041
regulation of neuron projection development GO:0010975 69 0.041
glycosyl compound metabolic process GO:1901657 127 0.041
developmental cell growth GO:0048588 52 0.041
regulation of nuclear division GO:0051783 58 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.040
nucleoside phosphate catabolic process GO:1901292 110 0.040
male gamete generation GO:0048232 201 0.039
positive regulation of lipid biosynthetic process GO:0046889 3 0.039
regulation of protein modification process GO:0031399 112 0.039
nucleobase containing compound transport GO:0015931 56 0.038
protein localization to nucleus GO:0034504 55 0.038
developmental growth GO:0048589 280 0.037
protein deneddylation GO:0000338 8 0.037
single organism nuclear import GO:1902593 51 0.037
neural precursor cell proliferation GO:0061351 75 0.037
protein transport GO:0015031 155 0.037
mitochondrion distribution GO:0048311 10 0.037
apoptotic process GO:0006915 159 0.037
organic cyclic compound catabolic process GO:1901361 168 0.036
aromatic compound catabolic process GO:0019439 166 0.036
regulation of protein localization to plasma membrane GO:1903076 7 0.035
regulation of neuron differentiation GO:0045664 103 0.035
dorsal closure GO:0007391 79 0.035
regulation of cellular response to stress GO:0080135 89 0.035
regulation of protein complex assembly GO:0043254 42 0.034
organophosphate catabolic process GO:0046434 112 0.034
transmembrane transport GO:0055085 139 0.034
synapse assembly GO:0007416 143 0.034
regulation of synapse structure and activity GO:0050803 128 0.034
single organism intracellular transport GO:1902582 207 0.034
single organism membrane organization GO:0044802 93 0.033
macromolecule catabolic process GO:0009057 161 0.033
protein modification by small protein conjugation or removal GO:0070647 106 0.033
nucleotide catabolic process GO:0009166 109 0.033
spindle localization GO:0051653 22 0.033
ribonucleoside metabolic process GO:0009119 127 0.032
regulation of hemocyte proliferation GO:0035206 37 0.032
regulation of developmental growth GO:0048638 174 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.032
regulation of protein stability GO:0031647 43 0.032
purine containing compound catabolic process GO:0072523 112 0.032
nucleoside triphosphate catabolic process GO:0009143 108 0.031
neuron projection guidance GO:0097485 241 0.031
nitrogen compound transport GO:0071705 85 0.031
regulation of cell death GO:0010941 173 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
positive regulation of multicellular organismal process GO:0051240 143 0.030
regulation of cytoplasmic transport GO:1903649 47 0.030
spermatid differentiation GO:0048515 114 0.029
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.029
regulation of multicellular organismal development GO:2000026 414 0.029
epithelial cell differentiation GO:0030855 322 0.029
negative regulation of phosphate metabolic process GO:0045936 45 0.029
establishment of rna localization GO:0051236 47 0.029
salivary gland development GO:0007431 162 0.028
rna processing GO:0006396 147 0.028
head development GO:0060322 135 0.028
peptidyl threonine modification GO:0018210 3 0.027
establishment of spindle localization GO:0051293 22 0.027
regulation of synaptic plasticity GO:0048167 14 0.027
posttranscriptional gene silencing GO:0016441 46 0.027
catabolic process GO:0009056 409 0.027
modification dependent protein catabolic process GO:0019941 78 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.026
ribonucleoside monophosphate catabolic process GO:0009158 39 0.026
purine nucleoside catabolic process GO:0006152 112 0.025
positive regulation of intracellular transport GO:0032388 42 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
phosphorylation GO:0016310 294 0.025
autophagy GO:0006914 108 0.024
lipid storage GO:0019915 38 0.024
synaptic growth at neuromuscular junction GO:0051124 119 0.024
mesenchymal cell development GO:0014031 1 0.024
mapk cascade GO:0000165 107 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
response to other organism GO:0051707 293 0.024
regulation of transport GO:0051049 181 0.024
regulation of notch signaling pathway GO:0008593 100 0.023
translation GO:0006412 69 0.023
plasma membrane organization GO:0007009 26 0.023
nucleotide metabolic process GO:0009117 161 0.023
rna transport GO:0050658 46 0.023
oocyte differentiation GO:0009994 145 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
fertilization GO:0009566 26 0.023
purine containing compound metabolic process GO:0072521 155 0.023
cellular protein modification process GO:0006464 438 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
protein modification by small protein removal GO:0070646 28 0.022
synapse organization GO:0050808 196 0.022
gland morphogenesis GO:0022612 145 0.021
salivary gland morphogenesis GO:0007435 145 0.021
negative regulation of neuron death GO:1901215 18 0.021
protein targeting to nucleus GO:0044744 51 0.021
cell projection assembly GO:0030031 94 0.021
cation transport GO:0006812 110 0.021
cell motility GO:0048870 251 0.021
compound eye photoreceptor cell differentiation GO:0001751 140 0.020
spindle assembly involved in mitosis GO:0090307 50 0.020
regulation of anatomical structure size GO:0090066 163 0.020
nucleocytoplasmic transport GO:0006913 72 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
central nervous system development GO:0007417 201 0.019
regulation of molecular function GO:0065009 217 0.019
positive regulation of signaling GO:0023056 243 0.019
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.019
actin cytoskeleton organization GO:0030036 206 0.019
proteasomal protein catabolic process GO:0010498 59 0.019
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.019
signal release GO:0023061 49 0.019
cilium assembly GO:0042384 38 0.019
forebrain development GO:0030900 2 0.018
atp catabolic process GO:0006200 38 0.018
establishment of nucleus localization GO:0040023 26 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
neurological system process GO:0050877 358 0.018
regulation of intracellular transport GO:0032386 64 0.018
developmental growth involved in morphogenesis GO:0060560 65 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.017
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.017
regulation of mitosis GO:0007088 56 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.017
rna localization GO:0006403 115 0.017
cilium organization GO:0044782 41 0.017
reproductive behavior GO:0019098 122 0.017
terminal button organization GO:0072553 19 0.017
exocytosis GO:0006887 28 0.017
synaptic vesicle recycling GO:0036465 28 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
cell recognition GO:0008037 102 0.017
stress activated mapk cascade GO:0051403 52 0.016
response to growth factor GO:0070848 31 0.016
cell maturation GO:0048469 144 0.016
organophosphate metabolic process GO:0019637 195 0.016
organonitrogen compound metabolic process GO:1901564 318 0.016
stress activated protein kinase signaling cascade GO:0031098 55 0.016
negative regulation of catabolic process GO:0009895 36 0.016
notch signaling pathway GO:0007219 120 0.016
spermatogenesis GO:0007283 200 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
positive regulation of endocytosis GO:0045807 22 0.016
development of primary sexual characteristics GO:0045137 50 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
tube development GO:0035295 244 0.016
locomotory behavior GO:0007626 176 0.015
cell proliferation GO:0008283 299 0.015
chromosome segregation GO:0007059 157 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
nuclear import GO:0051170 51 0.015
nucleoside metabolic process GO:0009116 127 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
receptor mediated endocytosis GO:0006898 21 0.015
developmental programmed cell death GO:0010623 138 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
establishment of cell polarity GO:0030010 40 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
nuclear transport GO:0051169 72 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
regulation of microtubule based process GO:0032886 49 0.014
microtubule anchoring GO:0034453 11 0.014
regulation of cellular protein catabolic process GO:1903362 44 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
cellular response to chemical stimulus GO:0070887 199 0.013
positive regulation of neurogenesis GO:0050769 41 0.013
response to starvation GO:0042594 97 0.013
energy derivation by oxidation of organic compounds GO:0015980 32 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
lipid transport GO:0006869 18 0.013
positive regulation of chromatin modification GO:1903310 17 0.013
germarium derived egg chamber formation GO:0007293 101 0.013
epithelial cell development GO:0002064 274 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
response to radiation GO:0009314 155 0.013
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.013
organelle fusion GO:0048284 46 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
ovarian follicle cell migration GO:0007297 121 0.012
regulation of protein targeting GO:1903533 29 0.012
regulation of protein localization GO:0032880 76 0.012
protein catabolic process GO:0030163 101 0.012
eye development GO:0001654 323 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
body morphogenesis GO:0010171 2 0.012
dna dependent dna replication maintenance of fidelity GO:0045005 0 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
regulation of intracellular protein transport GO:0033157 46 0.012
protein processing GO:0016485 68 0.012
gonad development GO:0008406 50 0.012
negative regulation of catalytic activity GO:0043086 42 0.012
regulation of nucleocytoplasmic transport GO:0046822 35 0.012
positive regulation of nervous system development GO:0051962 69 0.012
genitalia development GO:0048806 26 0.012
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.011
regulation of neuronal synaptic plasticity GO:0048168 8 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
mitochondrial fission GO:0000266 8 0.011
hair cell differentiation GO:0035315 47 0.011
oxoacid metabolic process GO:0043436 103 0.011
meiotic cell cycle process GO:1903046 132 0.011
sister chromatid segregation GO:0000819 92 0.011
response to extracellular stimulus GO:0009991 116 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
response to biotic stimulus GO:0009607 294 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
regulation of microtubule cytoskeleton organization GO:0070507 41 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
trna modification GO:0006400 2 0.011
nucleic acid transport GO:0050657 46 0.010
r7 cell differentiation GO:0045466 43 0.010
negative regulation of neurogenesis GO:0050768 53 0.010
regulation of catalytic activity GO:0050790 185 0.010
regulation of cell development GO:0060284 215 0.010
embryonic morphogenesis GO:0048598 206 0.010
regulation of mitotic sister chromatid segregation GO:0033047 28 0.010
protein localization to plasma membrane GO:0072659 13 0.010
regulation of mapk cascade GO:0043408 92 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010

Pp2A-29B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
central nervous system disease DOID:331 0 0.014
neurodegenerative disease DOID:1289 0 0.014