|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.968
|
Human Mouse Fly |
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.903
|
Human Mouse Fly |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
332 |
0.894
|
Human Mouse Fly |
|
|
regulation of nervous system development
|
GO:0051960 |
248 |
0.887
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.880
|
Human Mouse Fly |
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.867
|
Human Mouse Fly |
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.844
|
Human Worm |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.802
|
Human Mouse Fly |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.797
|
Human Mouse Worm Fly |
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
1 |
0.788
|
Mouse |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.786
|
Human Mouse Worm Fly |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.781
|
Human Worm |
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.770
|
Human Mouse Fly |
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.752
|
Human Mouse Fly |
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
204 |
0.731
|
Human Mouse Fly |
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
256 |
0.687
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.680
|
Human Worm |
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
67 |
0.674
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.666
|
Human Mouse Worm Fly |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.654
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.643
|
Human Worm |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
4 |
0.626
|
|
|
|
stem cell maintenance
|
GO:0019827 |
67 |
0.601
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
3 |
0.581
|
Fly |
|
|
cellular response to chemical stimulus
|
GO:0070887 |
199 |
0.558
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
3 |
0.549
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
104 |
0.548
|
Mouse |
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
1 |
0.546
|
Mouse |
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.545
|
Human Mouse Fly |
|
|
synapse organization
|
GO:0050808 |
196 |
0.531
|
|
|
|
developmental growth
|
GO:0048589 |
280 |
0.529
|
|
|
|
determination of ventral identity
|
GO:0048264 |
1 |
0.517
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.486
|
Fly |
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.464
|
Human Worm |
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.453
|
Human Mouse Fly |
|
|
cell proliferation
|
GO:0008283 |
299 |
0.434
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
103 |
0.429
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
158 |
0.425
|
|
|
|
synapse assembly
|
GO:0007416 |
143 |
0.418
|
|
|
|
compound eye morphogenesis
|
GO:0001745 |
249 |
0.413
|
Fly |
|
|
response to gravity
|
GO:0009629 |
26 |
0.412
|
|
|
|
phosphorylation
|
GO:0016310 |
294 |
0.411
|
Mouse Fly |
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
139 |
0.401
|
Mouse |
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.400
|
Human Fly |
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
3 |
0.392
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.390
|
|
|
|
heart field specification
|
GO:0003128 |
0 |
0.380
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
9 |
0.379
|
Human Mouse |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.365
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
4 |
0.365
|
|
|
|
neurological system process
|
GO:0050877 |
358 |
0.359
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
174 |
0.356
|
Mouse Fly |
|
|
cellular response to organic substance
|
GO:0071310 |
132 |
0.351
|
|
|
|
epithelial cell development
|
GO:0002064 |
274 |
0.351
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.349
|
Mouse |
|
|
endoderm formation
|
GO:0001706 |
3 |
0.343
|
Fly |
|
|
regulation of defense response
|
GO:0031347 |
102 |
0.338
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
46 |
0.338
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
27 |
0.336
|
Human Fly |
|
|
ectodermal placode morphogenesis
|
GO:0071697 |
4 |
0.334
|
|
|
|
axonogenesis
|
GO:0007409 |
290 |
0.328
|
|
|
|
stem cell proliferation
|
GO:0072089 |
88 |
0.328
|
|
|
|
embryonic hindgut morphogenesis
|
GO:0048619 |
48 |
0.323
|
Fly |
|
|
immune effector process
|
GO:0002252 |
98 |
0.320
|
|
|
|
intracellular transport
|
GO:0046907 |
228 |
0.316
|
Mouse |
|
|
protein phosphorylation
|
GO:0006468 |
169 |
0.309
|
Mouse |
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
81 |
0.308
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
3 |
0.308
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.306
|
Human Worm |
|
|
mitotic cytokinesis
|
GO:0000281 |
50 |
0.304
|
|
|
|
cell motility
|
GO:0048870 |
251 |
0.302
|
Fly |
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
240 |
0.299
|
Human Worm |
|
|
mesoderm formation
|
GO:0001707 |
21 |
0.290
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
260 |
0.290
|
Fly |
|
|
connective tissue development
|
GO:0061448 |
3 |
0.289
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
1 |
0.289
|
|
|
|
germ line stem cell division
|
GO:0042078 |
25 |
0.286
|
|
|
|
imaginal disc derived wing vein morphogenesis
|
GO:0008586 |
44 |
0.284
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
69 |
0.282
|
Mouse |
|
|
imaginal disc pattern formation
|
GO:0007447 |
91 |
0.269
|
Fly |
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
1 |
0.261
|
Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
87 |
0.261
|
Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
64 |
0.259
|
Mouse |
|
|
regulation of cell proliferation involved in imaginal disc derived wing morphogenesis
|
GO:0090256 |
2 |
0.259
|
Fly |
|
|
neuroblast proliferation
|
GO:0007405 |
74 |
0.258
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
92 |
0.256
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
270 |
0.255
|
Human Worm |
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.254
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
92 |
0.251
|
|
|
|
compound eye photoreceptor cell differentiation
|
GO:0001751 |
140 |
0.251
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
89 |
0.250
|
|
|
|
axis specification
|
GO:0009798 |
167 |
0.250
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
220 |
0.250
|
Mouse |
|
|
defense response to fungus
|
GO:0050832 |
48 |
0.245
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.240
|
Human Mouse |
|
|
response to organic substance
|
GO:0010033 |
284 |
0.237
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.232
|
Human Worm Fly |
|
|
regulation of notch signaling pathway
|
GO:0008593 |
100 |
0.232
|
|
|
|
growth
|
GO:0040007 |
359 |
0.231
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.230
|
Fly |
|
|
protein complex biogenesis
|
GO:0070271 |
201 |
0.214
|
Human |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
4 |
0.213
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
210 |
0.210
|
Mouse Fly |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.208
|
Human Mouse |
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.205
|
Human Worm Fly |
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.204
|
Mouse Fly |
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.203
|
Human Mouse |
|
|
eye morphogenesis
|
GO:0048592 |
260 |
0.202
|
Fly |
|
|
kidney development
|
GO:0001822 |
3 |
0.201
|
Mouse |
|
|
regulation of transport
|
GO:0051049 |
181 |
0.199
|
Mouse |
|
|
protein modification process
|
GO:0036211 |
438 |
0.198
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
130 |
0.198
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.195
|
|
|
|
sensory perception
|
GO:0007600 |
196 |
0.193
|
|
|
|
central nervous system development
|
GO:0007417 |
201 |
0.189
|
Fly |
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.188
|
Fly |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.188
|
Fly |
|
|
regulation of developmental growth
|
GO:0048638 |
174 |
0.186
|
|
|
|
regulation of cell development
|
GO:0060284 |
215 |
0.185
|
Mouse |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
109 |
0.185
|
Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
119 |
0.184
|
Worm |
|
|
inter male aggressive behavior
|
GO:0002121 |
60 |
0.179
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
69 |
0.177
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
240 |
0.177
|
Human Worm |
|
|
regulation of blood circulation
|
GO:1903522 |
21 |
0.174
|
|
|
|
forebrain development
|
GO:0030900 |
2 |
0.171
|
|
|
|
muscle structure development
|
GO:0061061 |
224 |
0.165
|
Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
90 |
0.165
|
|
|
|
positive regulation of antifungal peptide biosynthetic process
|
GO:0006967 |
5 |
0.164
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
242 |
0.161
|
Mouse Fly |
|
|
regulation of protein phosphorylation
|
GO:0001932 |
64 |
0.160
|
Mouse |
|
|
ectodermal placode development
|
GO:0071696 |
4 |
0.160
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
89 |
0.159
|
|
|
|
dorsal ventral axis specification
|
GO:0009950 |
66 |
0.157
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
61 |
0.155
|
Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.153
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
69 |
0.153
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
112 |
0.151
|
Mouse |
|
|
male gamete generation
|
GO:0048232 |
201 |
0.151
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
195 |
0.150
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
107 |
0.147
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
97 |
0.147
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
44 |
0.143
|
|
|
|
mapk cascade
|
GO:0000165 |
107 |
0.142
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
133 |
0.140
|
|
|
|
camera type eye development
|
GO:0043010 |
4 |
0.138
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
99 |
0.137
|
|
|
|
kidney epithelium development
|
GO:0072073 |
3 |
0.137
|
Mouse |
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.137
|
|
|
|
hindbrain development
|
GO:0030902 |
2 |
0.136
|
|
|
|
response to fungus
|
GO:0009620 |
50 |
0.134
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.133
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
4 |
0.131
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.131
|
Human Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
143 |
0.130
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
5 |
0.130
|
Human |
|
|
negative regulation of cell cell adhesion
|
GO:0022408 |
8 |
0.130
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
201 |
0.129
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
199 |
0.128
|
|
|
|
heart development
|
GO:0007507 |
82 |
0.128
|
Mouse |
|
|
single organism intracellular transport
|
GO:1902582 |
207 |
0.127
|
Mouse |
|
|
cellular protein complex assembly
|
GO:0043623 |
71 |
0.127
|
Human |
|
|
protein transport
|
GO:0015031 |
155 |
0.126
|
Mouse |
|
|
cell proliferation involved in imaginal disc derived wing morphogenesis
|
GO:0090255 |
2 |
0.125
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.125
|
Fly |
|
|
muscle organ development
|
GO:0007517 |
127 |
0.125
|
Fly |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.124
|
Mouse |
|
|
sex differentiation
|
GO:0007548 |
81 |
0.123
|
Worm |
|
|
actin cytoskeleton organization
|
GO:0030036 |
206 |
0.122
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.122
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.122
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
47 |
0.121
|
Mouse |
|
|
immune response
|
GO:0006955 |
246 |
0.119
|
|
|
|
regulation of synapse structure and activity
|
GO:0050803 |
128 |
0.119
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
185 |
0.119
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
50 |
0.118
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
119 |
0.117
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
149 |
0.117
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
51 |
0.117
|
Mouse |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
276 |
0.117
|
Mouse Fly |
|
|
establishment of protein localization
|
GO:0045184 |
163 |
0.116
|
Mouse |
|
|
regulation of cellular localization
|
GO:0060341 |
136 |
0.116
|
Mouse |
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.115
|
|
|
|
gliogenesis
|
GO:0042063 |
80 |
0.115
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.114
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
14 |
0.112
|
|
|
|
immune system process
|
GO:0002376 |
347 |
0.111
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
22 |
0.111
|
|
|
|
dendrite development
|
GO:0016358 |
204 |
0.110
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
50 |
0.110
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
32 |
0.110
|
|
|
|
catabolic process
|
GO:0009056 |
409 |
0.109
|
Human Worm Fly |
|
|
organ formation
|
GO:0048645 |
39 |
0.107
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
80 |
0.106
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
127 |
0.106
|
Mouse Fly |
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
4 |
0.105
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
139 |
0.104
|
Mouse |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
41 |
0.104
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
55 |
0.102
|
Mouse |
|
|
oxoacid metabolic process
|
GO:0043436 |
103 |
0.101
|
|
|
|
gastrulation
|
GO:0007369 |
70 |
0.100
|
Mouse Fly |
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
0.100
|
|
|
|
glandular epithelial cell differentiation
|
GO:0002067 |
1 |
0.099
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
3 |
0.098
|
|
|
|
single organism cellular localization
|
GO:1902580 |
180 |
0.097
|
Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
80 |
0.097
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.097
|
Mouse Worm |
|
|
protein complex assembly
|
GO:0006461 |
200 |
0.096
|
Human |
|
|
positive regulation of immune effector process
|
GO:0002699 |
28 |
0.096
|
|
|
|
eye development
|
GO:0001654 |
323 |
0.095
|
Fly |
|
|
single organism catabolic process
|
GO:0044712 |
228 |
0.095
|
|
|
|
synaptic transmission
|
GO:0007268 |
288 |
0.095
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.094
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.092
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.092
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.092
|
Mouse Fly |
|
|
regulation of localization
|
GO:0032879 |
275 |
0.092
|
Mouse |
|
|
homeostatic process
|
GO:0042592 |
199 |
0.091
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
131 |
0.091
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
1 |
0.091
|
Mouse |
|
|
organic substance transport
|
GO:0071702 |
257 |
0.087
|
Mouse |
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.087
|
Mouse |
|
|
mushroom body development
|
GO:0016319 |
70 |
0.087
|
Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
63 |
0.086
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
3 |
0.086
|
|
|
|
oocyte differentiation
|
GO:0009994 |
145 |
0.085
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
213 |
0.085
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
51 |
0.083
|
|
|
|
response to monosaccharide
|
GO:0034284 |
4 |
0.083
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
249 |
0.082
|
|
|
|
immune system development
|
GO:0002520 |
57 |
0.081
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
3 |
0.081
|
Mouse |
|
|
wing disc morphogenesis
|
GO:0007472 |
344 |
0.081
|
|
|
|
axon guidance
|
GO:0007411 |
233 |
0.080
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
105 |
0.079
|
Worm |
|
|
segmentation
|
GO:0035282 |
207 |
0.079
|
Mouse Fly |
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
3 |
0.079
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
31 |
0.078
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
40 |
0.078
|
|
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.078
|
Fly |
|
|
regulation of synaptic transmission
|
GO:0050804 |
69 |
0.078
|
|
|
|
mesoderm development
|
GO:0007498 |
78 |
0.077
|
Mouse |
|
|
maintenance of location
|
GO:0051235 |
73 |
0.077
|
|
|
|
reproductive system development
|
GO:0061458 |
74 |
0.077
|
|
|
|
maintenance of gastrointestinal epithelium
|
GO:0030277 |
3 |
0.077
|
|
|
|
nuclear import
|
GO:0051170 |
51 |
0.076
|
Mouse |
|
|
cytokinesis
|
GO:0000910 |
90 |
0.076
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
27 |
0.075
|
|
|
|
signal release
|
GO:0023061 |
49 |
0.075
|
|
|
|
compound eye photoreceptor fate commitment
|
GO:0001752 |
36 |
0.074
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
3 |
0.074
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
163 |
0.073
|
Mouse Fly |
|
|
brain development
|
GO:0007420 |
120 |
0.073
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
92 |
0.073
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
65 |
0.073
|
|
|
|
embryonic development via the syncytial blastoderm
|
GO:0001700 |
148 |
0.072
|
|
|
|
cellular response to lipid
|
GO:0071396 |
20 |
0.072
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.072
|
Fly |
|
|
hindgut morphogenesis
|
GO:0007442 |
58 |
0.071
|
Fly |
|
|
oocyte axis specification
|
GO:0007309 |
108 |
0.069
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
83 |
0.069
|
|
|
|
cell fate determination
|
GO:0001709 |
91 |
0.068
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
112 |
0.068
|
|
|
|
imaginal disc derived leg morphogenesis
|
GO:0007480 |
80 |
0.067
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
137 |
0.067
|
Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
109 |
0.066
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
47 |
0.066
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
2 |
0.066
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
78 |
0.065
|
Mouse Fly |
|
|
regulation of synapse organization
|
GO:0050807 |
110 |
0.065
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
18 |
0.065
|
|
|
|
tricarboxylic acid metabolic process
|
GO:0072350 |
1 |
0.064
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.064
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
38 |
0.064
|
Human Mouse Fly |
|
|
regulation of system process
|
GO:0044057 |
36 |
0.064
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
43 |
0.064
|
|
|
|
innate immune response
|
GO:0045087 |
144 |
0.063
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
1 |
0.063
|
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.063
|
Mouse |
|
|
regulation of innate immune response
|
GO:0045088 |
71 |
0.062
|
|
|
|
positive regulation of growth
|
GO:0045927 |
75 |
0.061
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
2 |
0.061
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
237 |
0.061
|
Human Worm |
|
|
endoderm development
|
GO:0007492 |
6 |
0.061
|
Mouse Fly |
|
|
cardiocyte differentiation
|
GO:0035051 |
29 |
0.061
|
Mouse |
|
|
single organism behavior
|
GO:0044708 |
391 |
0.061
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
39 |
0.060
|
|
|
|
organelle fusion
|
GO:0048284 |
46 |
0.060
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
163 |
0.059
|
Mouse |
|
|
wing disc pattern formation
|
GO:0035222 |
66 |
0.059
|
Fly |
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.059
|
Human Mouse Worm |
|
|
head development
|
GO:0060322 |
135 |
0.059
|
Fly |
|
|
instar larval development
|
GO:0002168 |
55 |
0.058
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.058
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
12 |
0.058
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
68 |
0.058
|
|
|
|
lipid metabolic process
|
GO:0006629 |
121 |
0.058
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
52 |
0.058
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
157 |
0.056
|
Fly |
|
|
humoral immune response
|
GO:0006959 |
117 |
0.056
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
74 |
0.056
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
143 |
0.056
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
58 |
0.056
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
47 |
0.054
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
57 |
0.054
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
116 |
0.054
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
47 |
0.054
|
|
|
|
cell death
|
GO:0008219 |
279 |
0.054
|
Mouse |
|
|
nucleotide catabolic process
|
GO:0009166 |
109 |
0.053
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
46 |
0.053
|
Mouse |
|
|
death
|
GO:0016265 |
284 |
0.053
|
Mouse |
|
|
response to other organism
|
GO:0051707 |
293 |
0.053
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
136 |
0.053
|
|
|
|
response to hexose
|
GO:0009746 |
3 |
0.053
|
|
|
|
compound eye development
|
GO:0048749 |
307 |
0.053
|
Fly |
|
|
regulation of immune response
|
GO:0050776 |
118 |
0.052
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
256 |
0.052
|
Human |
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.051
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.050
|
Worm Fly |
|
|
organelle localization
|
GO:0051640 |
148 |
0.050
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
23 |
0.050
|
Human |
|
|
anatomical structure homeostasis
|
GO:0060249 |
97 |
0.050
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
61 |
0.050
|
Mouse |
|
|
epithelial cell migration open tracheal system
|
GO:0007427 |
32 |
0.050
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
31 |
0.049
|
Fly |
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
17 |
0.049
|
|
|
|
programmed cell death
|
GO:0012501 |
257 |
0.049
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
34 |
0.049
|
|
|
|
biological adhesion
|
GO:0022610 |
138 |
0.048
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
116 |
0.048
|
Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
297 |
0.048
|
Mouse Fly |
|
|
formation of primary germ layer
|
GO:0001704 |
24 |
0.048
|
Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
143 |
0.048
|
|
|
|
amine metabolic process
|
GO:0009308 |
12 |
0.047
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
15 |
0.047
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
23 |
0.047
|
Fly |
|
|
stem cell division
|
GO:0017145 |
69 |
0.047
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
152 |
0.046
|
Mouse |
|
|
notch signaling pathway
|
GO:0007219 |
120 |
0.046
|
|
|
|
single organism nuclear import
|
GO:1902593 |
51 |
0.046
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
119 |
0.046
|
|
|
|
embryonic axis specification
|
GO:0000578 |
107 |
0.046
|
Mouse |
|
|
leg disc development
|
GO:0035218 |
92 |
0.045
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
26 |
0.045
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
138 |
0.045
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
105 |
0.045
|
|
|
|
autophagy
|
GO:0006914 |
108 |
0.045
|
Fly |
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
2 |
0.044
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
40 |
0.044
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
53 |
0.044
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.043
|
|
|
|
defense response to bacterium
|
GO:0042742 |
178 |
0.043
|
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.043
|
|
|
|
respiratory system development
|
GO:0060541 |
213 |
0.043
|
|
|
|
cell maturation
|
GO:0048469 |
144 |
0.042
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.042
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
36 |
0.042
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
118 |
0.042
|
|
|
|
germarium derived egg chamber formation
|
GO:0007293 |
101 |
0.042
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
109 |
0.041
|
Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
79 |
0.041
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
2 |
0.041
|
|
|
|
dorsal closure
|
GO:0007391 |
79 |
0.041
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
117 |
0.041
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
75 |
0.041
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
119 |
0.041
|
|
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.041
|
Mouse Fly |
|
|
regulation of protein localization
|
GO:0032880 |
76 |
0.040
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
55 |
0.040
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
294 |
0.040
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
103 |
0.040
|
|
|
|
gtp catabolic process
|
GO:0006184 |
72 |
0.040
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
14 |
0.040
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
39 |
0.040
|
|
|
|
response to glucose
|
GO:0009749 |
2 |
0.039
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
58 |
0.039
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
83 |
0.039
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
2 |
0.039
|
|
|
|
establishment of epithelial cell apical basal polarity
|
GO:0045198 |
10 |
0.039
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
14 |
0.039
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
161 |
0.038
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
30 |
0.038
|
|
|
|
ovarian follicle cell development
|
GO:0030707 |
248 |
0.038
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
92 |
0.038
|
|
|
|
positive regulation of synapse assembly
|
GO:0051965 |
29 |
0.038
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
58 |
0.038
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
127 |
0.037
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
3 |
0.037
|
Mouse |
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
145 |
0.037
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
103 |
0.037
|
Fly |
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
34 |
0.037
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
217 |
0.037
|
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.036
|
|
|
|
cellular protein localization
|
GO:0034613 |
160 |
0.036
|
Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
109 |
0.036
|
|
|
|
regulation of organ formation
|
GO:0003156 |
3 |
0.036
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
38 |
0.036
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
151 |
0.036
|
|
|
|
organ growth
|
GO:0035265 |
56 |
0.036
|
Worm |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
103 |
0.036
|
Fly |
|
|
response to acid chemical
|
GO:0001101 |
25 |
0.036
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
38 |
0.036
|
|
|
|
ion transport
|
GO:0006811 |
145 |
0.035
|
|
|
|
formation of anatomical boundary
|
GO:0048859 |
37 |
0.035
|
Mouse |
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
63 |
0.035
|
|
|
|
defense response to other organism
|
GO:0098542 |
225 |
0.035
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
16 |
0.035
|
|
|
|
morphogenesis of larval imaginal disc epithelium
|
GO:0016335 |
5 |
0.034
|
Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.034
|
Human Worm |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.034
|
Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
89 |
0.034
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
72 |
0.034
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
140 |
0.034
|
Fly |
|
|
jnk cascade
|
GO:0007254 |
50 |
0.034
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
37 |
0.034
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
45 |
0.034
|
|
|
|
protein localization
|
GO:0008104 |
284 |
0.033
|
Mouse |
|
|
single organism biosynthetic process
|
GO:0044711 |
206 |
0.033
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
108 |
0.033
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
10 |
0.033
|
Fly |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
127 |
0.033
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
93 |
0.033
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
14 |
0.032
|
|
|
|
protein import
|
GO:0017038 |
55 |
0.032
|
Mouse |
|
|
anterior posterior pattern specification
|
GO:0009952 |
136 |
0.032
|
Mouse Fly |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
18 |
0.032
|
Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
46 |
0.032
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
9 |
0.032
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
44 |
0.032
|
|
|
|
oocyte development
|
GO:0048599 |
124 |
0.032
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.032
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
94 |
0.031
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
170 |
0.031
|
Human Worm Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
41 |
0.031
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
119 |
0.031
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
20 |
0.031
|
|
|
|
gtp metabolic process
|
GO:0046039 |
72 |
0.031
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
74 |
0.031
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
1 |
0.031
|
|
|
|
cellular transition metal ion homeostasis
|
GO:0046916 |
9 |
0.031
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
45 |
0.030
|
|
|
|
cell migration
|
GO:0016477 |
238 |
0.030
|
Fly |
|
|
regulation of steroid metabolic process
|
GO:0019218 |
2 |
0.030
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
78 |
0.030
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
57 |
0.030
|
|
|
|
actin filament based process
|
GO:0030029 |
220 |
0.030
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
153 |
0.030
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
55 |
0.030
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
63 |
0.030
|
|
|
|
stem cell development
|
GO:0048864 |
79 |
0.030
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
45 |
0.030
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
55 |
0.029
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
34 |
0.029
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
29 |
0.029
|
|
|
|
genital disc development
|
GO:0035215 |
44 |
0.029
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
42 |
0.029
|
|
|
|
renal system development
|
GO:0072001 |
72 |
0.029
|
Mouse Fly |
|
|
peptide transport
|
GO:0015833 |
10 |
0.029
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.029
|
Fly |
|
|
response to mechanical stimulus
|
GO:0009612 |
28 |
0.029
|
|
|
|
secretion by cell
|
GO:0032940 |
101 |
0.029
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
4 |
0.029
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
95 |
0.029
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
40 |
0.028
|
|
|
|
dna metabolic process
|
GO:0006259 |
227 |
0.028
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
83 |
0.028
|
|
|
|
protein targeting
|
GO:0006605 |
64 |
0.028
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
112 |
0.028
|
|
|
|
response to drug
|
GO:0042493 |
17 |
0.028
|
|
|
|
epithelial cell migration
|
GO:0010631 |
148 |
0.028
|
|
|
|
histone modification
|
GO:0016570 |
106 |
0.028
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
322 |
0.028
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
94 |
0.028
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
27 |
0.028
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
58 |
0.027
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
116 |
0.027
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
90 |
0.027
|
|
|
|
proteolysis
|
GO:0006508 |
192 |
0.027
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
18 |
0.027
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
26 |
0.027
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
19 |
0.027
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
88 |
0.027
|
|
|
|
chromosome condensation
|
GO:0030261 |
41 |
0.027
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
13 |
0.027
|
Fly |
|
|
regulation of protein catabolic process
|
GO:0042176 |
55 |
0.027
|
Human Worm |
|
|
protein localization to organelle
|
GO:0033365 |
82 |
0.027
|
Mouse |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
57 |
0.027
|
|
|
|
regulation of cuticle pigmentation
|
GO:0048079 |
16 |
0.027
|
|
|
|
oocyte construction
|
GO:0007308 |
112 |
0.026
|
|
|
|
open tracheal system development
|
GO:0007424 |
204 |
0.026
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
159 |
0.026
|
Fly |
|
|
jak stat cascade
|
GO:0007259 |
49 |
0.025
|
|
