Drosophila melanogaster

4 known processes

IM1 (Dmel_CG18108)

Immune induced molecule 1

(Aliases: BcDNA:RH08745,IM2-like,DIM 1,Dmel\CG18108,CG18108,DIM-1)

IM1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
antibacterial humoral response GO:0019731 44 0.971
defense response GO:0006952 300 0.779
humoral immune response GO:0006959 117 0.776
activation of innate immune response GO:0002218 4 0.663
defense response to gram positive bacterium GO:0050830 41 0.566
response to external biotic stimulus GO:0043207 293 0.494
immune response GO:0006955 246 0.467
defense response to bacterium GO:0042742 178 0.442
defense response to other organism GO:0098542 225 0.436
defense response to fungus GO:0050832 48 0.341
innate immune response activating signal transduction GO:0002758 2 0.323
pattern recognition receptor signaling pathway GO:0002221 2 0.310
response to bacterium GO:0009617 198 0.310
positive regulation of histone h3 k9 methylation GO:0051574 3 0.288
immune system process GO:0002376 347 0.286
response to other organism GO:0051707 293 0.257
killing of cells of other organism GO:0031640 1 0.218
response to biotic stimulus GO:0009607 294 0.188
antimicrobial humoral response GO:0019730 99 0.165
regulation of defense response GO:0031347 102 0.161
positive regulation of defense response GO:0031349 59 0.117
negative regulation of gene expression GO:0010629 387 0.116
peptidoglycan metabolic process GO:0000270 3 0.111
positive regulation of macromolecule metabolic process GO:0010604 405 0.098
organonitrogen compound metabolic process GO:1901564 318 0.097
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.095
transcription from rna polymerase ii promoter GO:0006366 368 0.093
positive regulation of protein metabolic process GO:0051247 128 0.091
chromosome organization GO:0051276 360 0.087
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.079
protein modification process GO:0036211 438 0.079
negative regulation of cellular biosynthetic process GO:0031327 277 0.077
innate immune response GO:0045087 144 0.076
glycosaminoglycan metabolic process GO:0030203 11 0.076
negative regulation of nucleic acid templated transcription GO:1903507 240 0.074
chromatin modification GO:0016568 147 0.071
histone modification GO:0016570 106 0.066
regulation of cellular protein metabolic process GO:0032268 243 0.065
regulation of protein metabolic process GO:0051246 256 0.057
male gamete generation GO:0048232 201 0.057
regulation of growth GO:0040008 233 0.056
posttranscriptional regulation of gene expression GO:0010608 145 0.055
regulation of organelle organization GO:0033043 196 0.054
regulation of innate immune response GO:0045088 71 0.052
covalent chromatin modification GO:0016569 106 0.049
wing disc morphogenesis GO:0007472 344 0.046
regulation of response to stress GO:0080134 200 0.046
methylation GO:0032259 47 0.046
positive regulation of cellular component organization GO:0051130 156 0.045
protein localization to chromatin GO:0071168 3 0.044
immune response regulating signaling pathway GO:0002764 2 0.042
response to organic substance GO:0010033 284 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.040
muscle structure development GO:0061061 224 0.039
regulation of chromosome organization GO:0033044 64 0.038
carbohydrate derivative metabolic process GO:1901135 217 0.038
protein localization GO:0008104 284 0.037
organic substance catabolic process GO:1901575 308 0.037
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.036
cellular protein modification process GO:0006464 438 0.034
macromolecule catabolic process GO:0009057 161 0.034
immune response activating signal transduction GO:0002757 2 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.033
response to fungus GO:0009620 50 0.033
protein alkylation GO:0008213 43 0.033
catabolic process GO:0009056 409 0.033
positive regulation of response to stimulus GO:0048584 323 0.033
regulation of chromatin modification GO:1903308 28 0.033
appendage development GO:0048736 401 0.032
histone methylation GO:0016571 40 0.032
histone lysine methylation GO:0034968 32 0.032
regulation of chromatin organization GO:1902275 32 0.031
positive regulation of immune system process GO:0002684 68 0.029
antifungal humoral response GO:0019732 12 0.029
positive regulation of innate immune response GO:0045089 38 0.029
regulation of immune system process GO:0002682 176 0.029
cellular amino acid metabolic process GO:0006520 61 0.027
establishment of protein localization GO:0045184 163 0.026
axis specification GO:0009798 167 0.026
positive regulation of signaling GO:0023056 243 0.026
negative regulation of biosynthetic process GO:0009890 277 0.025
macromolecule methylation GO:0043414 45 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
imaginal disc derived appendage development GO:0048737 399 0.025
small molecule metabolic process GO:0044281 305 0.025
phosphorylation GO:0016310 294 0.024
regulation of cell growth GO:0001558 43 0.024
positive regulation of organelle organization GO:0010638 65 0.024
amine catabolic process GO:0009310 1 0.023
negative regulation of rna biosynthetic process GO:1902679 240 0.023
regionalization GO:0003002 416 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
oxoacid metabolic process GO:0043436 103 0.022
positive regulation of cell communication GO:0010647 250 0.022
organic acid metabolic process GO:0006082 103 0.022
positive regulation of signal transduction GO:0009967 223 0.021
positive regulation of protein modification process GO:0031401 58 0.021
response to lipopolysaccharide GO:0032496 4 0.021
single organism behavior GO:0044708 391 0.021
chromatin organization GO:0006325 207 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
appendage morphogenesis GO:0035107 397 0.020
steroid catabolic process GO:0006706 1 0.020
negative regulation of transcription dna templated GO:0045892 237 0.020
positive regulation of antimicrobial humoral response GO:0002760 28 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
establishment of protein localization to organelle GO:0072594 62 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
xenobiotic catabolic process GO:0042178 1 0.020
spermatogenesis GO:0007283 200 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
acetate ester metabolic process GO:1900619 2 0.019
positive regulation of immune response GO:0050778 63 0.019
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.019
neuron projection guidance GO:0097485 241 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
body morphogenesis GO:0010171 2 0.018
intracellular signal transduction GO:0035556 300 0.018
purine containing compound metabolic process GO:0072521 155 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
respiratory system development GO:0060541 213 0.018
cellular response to starvation GO:0009267 61 0.018
growth GO:0040007 359 0.018
nuclear division GO:0000280 332 0.018
regulation of cell cycle GO:0051726 291 0.018
cellular response to dna damage stimulus GO:0006974 223 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
regulation of defense response to bacterium GO:1900424 30 0.017
negative regulation of cell communication GO:0010648 223 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
epithelial cell differentiation GO:0030855 322 0.017
response to radiation GO:0009314 155 0.017
vesicle mediated transport GO:0016192 381 0.017
maintenance of location GO:0051235 73 0.017
response to abiotic stimulus GO:0009628 341 0.017
forebrain development GO:0030900 2 0.017
phagocytosis GO:0006909 215 0.017
organelle fission GO:0048285 340 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.016
positive regulation of cell migration GO:0030335 2 0.016
spindle organization GO:0007051 253 0.016
taxis GO:0042330 304 0.016
cellular response to nutrient levels GO:0031669 62 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
synaptic transmission GO:0007268 288 0.016
regulation of nervous system development GO:0051960 248 0.016
cellular catabolic process GO:0044248 372 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
positive regulation of gene expression GO:0010628 290 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
amine metabolic process GO:0009308 12 0.016
neurotransmitter catabolic process GO:0042135 1 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
ethanolamine containing compound metabolic process GO:0042439 4 0.016
defense response to gram negative bacterium GO:0050829 94 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
cellular macromolecule localization GO:0070727 220 0.015
positive regulation of cell motility GO:2000147 3 0.015
cellular amine metabolic process GO:0044106 12 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
detection of chemical stimulus GO:0009593 93 0.015
cell cycle phase transition GO:0044770 140 0.015
protein phosphorylation GO:0006468 169 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
response to glucose GO:0009749 2 0.015
rna processing GO:0006396 147 0.015
cellular ketone metabolic process GO:0042180 24 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
mitotic nuclear division GO:0007067 213 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
camera type eye development GO:0043010 4 0.014
regulation of molecular function GO:0065009 217 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
ameboidal type cell migration GO:0001667 151 0.014
chromosome segregation GO:0007059 157 0.014
regulation of catalytic activity GO:0050790 185 0.014
axonogenesis GO:0007409 290 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
negative regulation of signal transduction GO:0009968 206 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
death GO:0016265 284 0.013
protein methylation GO:0006479 43 0.013
axon development GO:0061564 297 0.013
programmed cell death GO:0012501 257 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
gene silencing GO:0016458 138 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
response to starvation GO:0042594 97 0.013
melanization defense response GO:0035006 45 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
heterocycle catabolic process GO:0046700 166 0.013
eye development GO:0001654 323 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
nucleoside metabolic process GO:0009116 127 0.013
chemosensory behavior GO:0007635 106 0.013
positive regulation of antibacterial peptide production GO:0002803 20 0.013
cellular protein localization GO:0034613 160 0.013
meiotic cell cycle process GO:1903046 132 0.013
dorsal ventral axis specification GO:0009950 66 0.013
neurotransmitter metabolic process GO:0042133 2 0.013
segmentation GO:0035282 207 0.013
axon guidance GO:0007411 233 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
limb development GO:0060173 1 0.013
hindbrain development GO:0030902 2 0.012
endocytosis GO:0006897 310 0.012
positive regulation of molecular function GO:0044093 136 0.012
cellular response to ethanol GO:0071361 4 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
regulation of cell differentiation GO:0045595 302 0.012
cell death GO:0008219 279 0.012
neurological system process GO:0050877 358 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
regulation of protein modification process GO:0031399 112 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
regulation of cell cycle process GO:0010564 181 0.012
regulation of immune response GO:0050776 118 0.012
acetylcholine metabolic process GO:0008291 2 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
chaeta development GO:0022416 97 0.012
meiotic nuclear division GO:0007126 151 0.012
response to hexose GO:0009746 3 0.012
sulfur compound metabolic process GO:0006790 59 0.012
polyol biosynthetic process GO:0046173 3 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
negative regulation of signaling GO:0023057 219 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
developmental maturation GO:0021700 172 0.012
cell motility GO:0048870 251 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
estrogen metabolic process GO:0008210 1 0.012
positive regulation of catalytic activity GO:0043085 118 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
organelle assembly GO:0070925 198 0.011
compound eye development GO:0048749 307 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
intracellular transport GO:0046907 228 0.011
response to oxygen containing compound GO:1901700 200 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
developmental growth GO:0048589 280 0.011
cell division GO:0051301 248 0.011
detection of stimulus GO:0051606 156 0.011
ras protein signal transduction GO:0007265 88 0.011
open tracheal system development GO:0007424 204 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
anterior posterior pattern specification GO:0009952 136 0.011
regulation of gene silencing GO:0060968 63 0.011
cell migration GO:0016477 238 0.011
chemical homeostasis GO:0048878 92 0.011
translation GO:0006412 69 0.011
border follicle cell migration GO:0007298 113 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
homeostatic process GO:0042592 199 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
muscle organ development GO:0007517 127 0.011
telencephalon development GO:0021537 2 0.011
cell junction organization GO:0034330 57 0.011
camera type eye morphogenesis GO:0048593 2 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.011
cell recognition GO:0008037 102 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
connective tissue development GO:0061448 3 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
autophagy GO:0006914 108 0.011
response to nutrient levels GO:0031667 114 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
wound healing GO:0042060 75 0.011
cell adhesion GO:0007155 136 0.010
neuron recognition GO:0008038 101 0.010
regulation of cell development GO:0060284 215 0.010
blastoderm segmentation GO:0007350 159 0.010
retina development in camera type eye GO:0060041 4 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
regulation of cell death GO:0010941 173 0.010
mitotic spindle organization GO:0007052 220 0.010
limb morphogenesis GO:0035108 1 0.010
antimicrobial peptide biosynthetic process GO:0002777 38 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
mesenchymal cell development GO:0014031 1 0.010
regulation of catabolic process GO:0009894 170 0.010
sterol homeostasis GO:0055092 4 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
rrna processing GO:0006364 3 0.010

IM1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
artery disease DOID:0050828 0 0.016
vascular disease DOID:178 0 0.016
cardiovascular system disease DOID:1287 0 0.016
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.010