Drosophila melanogaster

70 known processes

trpl (Dmel_CG18345)

trp-like

(Aliases: trp-l,Dmel\CG18345,TRPL,TrpL,dTRPL,DmTRPL,CG18345,dTrpL,CG1694)

trpl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of visible light GO:0009584 38 1.000
phototransduction visible light GO:0007603 27 1.000
phototransduction GO:0007602 52 1.000
detection of light stimulus GO:0009583 58 1.000
rhodopsin mediated signaling pathway GO:0016056 21 1.000
Fly
deactivation of rhodopsin mediated signaling GO:0016059 17 1.000
sensory perception of sound GO:0007605 56 1.000
cellular response to light stimulus GO:0071482 37 1.000
Fly
light induced release of internally sequestered calcium ion GO:0008377 1 0.999
Fly
sensory perception GO:0007600 196 0.998
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.998
optomotor response GO:0071632 3 0.998
detection of stimulus GO:0051606 156 0.996
cellular response to radiation GO:0071478 52 0.995
Fly
detection of abiotic stimulus GO:0009582 66 0.995
thermotaxis GO:0043052 16 0.995
sensory perception of mechanical stimulus GO:0050954 72 0.994
response to light stimulus GO:0009416 124 0.989
detection of external stimulus GO:0009581 66 0.989
phototransduction uv GO:0007604 5 0.985
cellular response to uv GO:0034644 12 0.977
cellular response to abiotic stimulus GO:0071214 58 0.969
Fly
g protein coupled receptor signaling pathway GO:0007186 136 0.952
Fly
compound eye retinal cell programmed cell death GO:0046667 23 0.918
response to radiation GO:0009314 155 0.897
phospholipase c activating rhodopsin mediated signaling pathway GO:0030265 1 0.839
metal ion homeostasis GO:0055065 44 0.810
Human Fly
neurological system process GO:0050877 358 0.802
compound eye photoreceptor development GO:0042051 78 0.751
photoreceptor cell differentiation GO:0046530 170 0.730
response to abiotic stimulus GO:0009628 341 0.655
cellular divalent inorganic cation homeostasis GO:0072503 23 0.655
Human Fly
optokinetic behavior GO:0007634 3 0.640
cellular cation homeostasis GO:0030003 38 0.614
Human Fly
chemical homeostasis GO:0048878 92 0.612
Human Fly
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.601
response to uv GO:0009411 24 0.589
light absorption GO:0016037 2 0.583
absorption of uv light GO:0016039 1 0.579
cellular metal ion homeostasis GO:0006875 31 0.557
Human Fly
response to light intensity GO:0009642 6 0.552
homeostatic process GO:0042592 199 0.549
Human Fly
taxis GO:0042330 304 0.540
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.527
detection of stimulus involved in sensory perception GO:0050906 92 0.461
Fly
programmed cell death GO:0012501 257 0.435
ion homeostasis GO:0050801 55 0.425
Human Fly
regulation of cell death GO:0010941 173 0.424
regulation of localization GO:0032879 275 0.419
adult locomotory behavior GO:0008344 76 0.414
photoreceptor cell maintenance GO:0045494 11 0.401
negative regulation of homeostatic process GO:0032845 2 0.395
Human Fly
metarhodopsin inactivation GO:0016060 5 0.388
regulation of sequestering of calcium ion GO:0051282 3 0.365
Human Fly
negative regulation of retinal cell programmed cell death GO:0046671 7 0.355
adaptation of signaling pathway GO:0023058 3 0.350
eye morphogenesis GO:0048592 260 0.344
cell death GO:0008219 279 0.341
cell projection assembly GO:0030031 94 0.323
Zebrafish
purine ribonucleotide catabolic process GO:0009154 109 0.316
regulation of response to external stimulus GO:0032101 115 0.316
eye photoreceptor cell differentiation GO:0001754 145 0.313
transcription from rna polymerase ii promoter GO:0006366 368 0.312
locomotory behavior GO:0007626 176 0.309
calcium ion homeostasis GO:0055074 23 0.309
Human Fly
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.302
cellular calcium ion homeostasis GO:0006874 21 0.300
Human Fly
light adaption GO:0036367 3 0.299
regulation of anatomical structure morphogenesis GO:0022603 242 0.293
absorption of visible light GO:0016038 1 0.281
regulation of cell differentiation GO:0045595 302 0.281
maintenance of location GO:0051235 73 0.266
Fly
adaptation of rhodopsin mediated signaling GO:0016062 3 0.258
cellular chemical homeostasis GO:0055082 40 0.251
Human Fly
cation homeostasis GO:0055080 51 0.249
Human Fly
cellular ion homeostasis GO:0006873 39 0.243
Human Fly
divalent metal ion transport GO:0070838 26 0.230
regulation of multicellular organismal development GO:2000026 414 0.227
retinal cell programmed cell death GO:0046666 25 0.219
dopamine receptor signaling pathway GO:0007212 4 0.216
regulation of cell development GO:0060284 215 0.213
entrainment of circadian clock by photoperiod GO:0043153 9 0.211
sensory perception of light stimulus GO:0050953 12 0.209
Fly
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.204
metal ion transport GO:0030001 74 0.198
negative regulation of compound eye retinal cell programmed cell death GO:0046673 7 0.197
positive regulation of calcium ion transport GO:0051928 4 0.190
Human
death GO:0016265 284 0.185
regulation of retinal cell programmed cell death GO:0046668 18 0.180
cellular homeostasis GO:0019725 80 0.178
Human Fly
compound eye development GO:0048749 307 0.177
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.175
divalent inorganic cation transport GO:0072511 30 0.174
single organism behavior GO:0044708 391 0.173
Fly
developmental programmed cell death GO:0010623 138 0.172
divalent inorganic cation homeostasis GO:0072507 29 0.169
Human Fly
developmental pigmentation GO:0048066 68 0.166
regulation of ion homeostasis GO:2000021 5 0.165
Human Fly
eye development GO:0001654 323 0.159
sensory organ morphogenesis GO:0090596 260 0.153
cellular protein modification process GO:0006464 438 0.151
purine nucleoside triphosphate catabolic process GO:0009146 108 0.150
negative regulation of cell differentiation GO:0045596 143 0.148
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.148
compound eye photoreceptor cell differentiation GO:0001751 140 0.147
negative regulation of cell death GO:0060548 81 0.145
negative regulation of signal transduction GO:0009968 206 0.144
regulation of organ morphogenesis GO:2000027 78 0.144
entrainment of circadian clock GO:0009649 16 0.143
pigmentation GO:0043473 75 0.142
eye photoreceptor cell development GO:0042462 81 0.141
cell junction organization GO:0034330 57 0.140
positive regulation of molecular function GO:0044093 136 0.137
ion transport GO:0006811 145 0.136
establishment or maintenance of cell polarity GO:0007163 167 0.136
embryonic hindgut morphogenesis GO:0048619 48 0.135
learning GO:0007612 75 0.134
Fly
energy taxis GO:0009453 21 0.130
pigment metabolic process GO:0042440 84 0.126
compound eye morphogenesis GO:0001745 249 0.124
purine nucleoside metabolic process GO:0042278 127 0.122
rhabdomere development GO:0042052 38 0.122
cellular catabolic process GO:0044248 372 0.121
detection of light stimulus involved in sensory perception GO:0050962 9 0.117
Fly
morphogenesis of an epithelium GO:0002009 276 0.116
localization of cell GO:0051674 257 0.113
purine ribonucleoside metabolic process GO:0046128 127 0.111
circadian rhythm GO:0007623 105 0.111
bolwig s organ development GO:0055034 8 0.109
multicellular organismal homeostasis GO:0048871 41 0.108
cell cell junction organization GO:0045216 55 0.106
intracellular transport GO:0046907 228 0.106
Human
ameboidal type cell migration GO:0001667 151 0.106
negative regulation of developmental process GO:0051093 201 0.105
morphogenesis of a polarized epithelium GO:0001738 93 0.104
regulation of filopodium assembly GO:0051489 24 0.103
cation transport GO:0006812 110 0.101
negative regulation of transcription dna templated GO:0045892 237 0.100
positive regulation of response to stimulus GO:0048584 323 0.095
inorganic cation transmembrane transport GO:0098662 61 0.094
organonitrogen compound metabolic process GO:1901564 318 0.094
cellular ketone metabolic process GO:0042180 24 0.091
chromosome organization GO:0051276 360 0.089
sequestering of calcium ion GO:0051208 5 0.089
Fly
regulation of programmed cell death GO:0043067 152 0.088
negative regulation of cellular biosynthetic process GO:0031327 277 0.088
carbohydrate derivative metabolic process GO:1901135 217 0.087
regulation of transport GO:0051049 181 0.087
negative regulation of multicellular organismal process GO:0051241 142 0.086
calcium ion transport GO:0006816 24 0.085
chemotaxis GO:0006935 249 0.084
adult behavior GO:0030534 137 0.084
negative regulation of rna metabolic process GO:0051253 251 0.083
detection of uv GO:0009589 6 0.082
cell cell junction assembly GO:0007043 38 0.082
regulation of phosphate metabolic process GO:0019220 210 0.082
gtp metabolic process GO:0046039 72 0.082
ion transmembrane transport GO:0034220 122 0.081
negative regulation of sequestering of calcium ion GO:0051283 2 0.081
Human Fly
purine containing compound metabolic process GO:0072521 155 0.080
negative regulation of gene expression GO:0010629 387 0.079
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.079
small molecule metabolic process GO:0044281 305 0.079
regulation of body fluid levels GO:0050878 14 0.078
negative regulation of cellular metabolic process GO:0031324 382 0.078
cation transmembrane transport GO:0098655 88 0.076
response to temperature stimulus GO:0009266 106 0.075
neuroblast division GO:0055057 35 0.075
protein modification process GO:0036211 438 0.075
organophosphate catabolic process GO:0046434 112 0.074
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.073
photoperiodism GO:0009648 10 0.072
peptidyl tyrosine modification GO:0018212 24 0.071
nucleoside metabolic process GO:0009116 127 0.071
response to carbon dioxide GO:0010037 4 0.070
olfactory learning GO:0008355 56 0.068
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.068
negative regulation of response to stimulus GO:0048585 258 0.068
positive regulation of catalytic activity GO:0043085 118 0.068
cellular response to lipopolysaccharide GO:0071222 3 0.067
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.067
carbohydrate derivative catabolic process GO:1901136 118 0.067
vesicle mediated transport GO:0016192 381 0.064
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.063
regulation of circadian rhythm GO:0042752 49 0.062
nucleoside triphosphate catabolic process GO:0009143 108 0.060
peptidyl amino acid modification GO:0018193 105 0.060
purine nucleoside triphosphate metabolic process GO:0009144 119 0.060
cellular nitrogen compound catabolic process GO:0044270 165 0.059
cell adhesion GO:0007155 136 0.058
forebrain development GO:0030900 2 0.058
regulation of molecular function GO:0065009 217 0.058
organic substance transport GO:0071702 257 0.058
Mouse
proteolysis GO:0006508 192 0.057
axis specification GO:0009798 167 0.057
positive regulation of behavior GO:0048520 19 0.057
filopodium assembly GO:0046847 33 0.057
Zebrafish
protein localization GO:0008104 284 0.057
Fly
asymmetric neuroblast division GO:0055059 33 0.057
rhythmic process GO:0048511 106 0.057
immune response GO:0006955 246 0.057
retina homeostasis GO:0001895 13 0.056
dna metabolic process GO:0006259 227 0.056
negative regulation of programmed cell death GO:0043069 72 0.055
biological adhesion GO:0022610 138 0.055
ribonucleotide catabolic process GO:0009261 109 0.055
female gonad development GO:0008585 12 0.054
ribonucleoside catabolic process GO:0042454 112 0.054
cellular macromolecule catabolic process GO:0044265 136 0.054
regulation of phosphorus metabolic process GO:0051174 210 0.053
purine ribonucleoside catabolic process GO:0046130 112 0.052
asymmetric stem cell division GO:0098722 49 0.052
isoprenoid transport GO:0046864 2 0.052
long term memory GO:0007616 62 0.052
regulation of cellular amino acid metabolic process GO:0006521 0 0.051
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 10 0.051
phosphorylation GO:0016310 294 0.051
nucleoside phosphate metabolic process GO:0006753 162 0.051
phototaxis GO:0042331 21 0.051
olfactory behavior GO:0042048 97 0.050
Fly
regulation of intracellular signal transduction GO:1902531 236 0.050
epithelial cell migration GO:0010631 148 0.050
protein phosphorylation GO:0006468 169 0.050
pupal development GO:0035209 11 0.050
regulation of cellular amine metabolic process GO:0033238 3 0.050
negative regulation of phosphorus metabolic process GO:0010563 45 0.049
ubiquitin dependent protein catabolic process GO:0006511 78 0.048
tissue death GO:0016271 102 0.048
purine nucleotide metabolic process GO:0006163 146 0.047
nucleobase containing compound catabolic process GO:0034655 165 0.047
regulation of membrane potential GO:0042391 35 0.047
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.047
modification dependent macromolecule catabolic process GO:0043632 79 0.047
somatic stem cell division GO:0048103 37 0.046
regulation of catalytic activity GO:0050790 185 0.046
regionalization GO:0003002 416 0.046
purine nucleotide catabolic process GO:0006195 109 0.046
positive regulation of cellular component biogenesis GO:0044089 80 0.046
peptidyl threonine modification GO:0018210 3 0.045
cardiovascular system development GO:0072358 82 0.045
Zebrafish
tissue morphogenesis GO:0048729 297 0.045
photoreceptor cell development GO:0042461 96 0.045
digestive tract morphogenesis GO:0048546 127 0.044
covalent chromatin modification GO:0016569 106 0.044
establishment of tissue polarity GO:0007164 87 0.044
positive regulation of cell communication GO:0010647 250 0.044
aromatic compound catabolic process GO:0019439 166 0.044
negative regulation of biosynthetic process GO:0009890 277 0.043
nucleobase containing small molecule metabolic process GO:0055086 174 0.043
intracellular signal transduction GO:0035556 300 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.043
ribonucleotide metabolic process GO:0009259 145 0.043
negative regulation of cell communication GO:0010648 223 0.043
single organism intracellular transport GO:1902582 207 0.043
Human
exocrine system development GO:0035272 162 0.042
gland morphogenesis GO:0022612 145 0.042
response to bacterium GO:0009617 198 0.042
establishment of localization in cell GO:0051649 402 0.042
Human
negative regulation of catalytic activity GO:0043086 42 0.041
monocarboxylic acid transport GO:0015718 3 0.041
Mouse
ribonucleoside metabolic process GO:0009119 127 0.041
gliogenesis GO:0042063 80 0.041
Mouse
apoptotic process GO:0006915 159 0.041
regulation of mapk cascade GO:0043408 92 0.041
negative regulation of rna biosynthetic process GO:1902679 240 0.040
signal transduction by phosphorylation GO:0023014 107 0.040
positive regulation of signal transduction GO:0009967 223 0.040
negative regulation of cell development GO:0010721 62 0.040
mitochondrion organization GO:0007005 65 0.040
mapk cascade GO:0000165 107 0.039
cell division GO:0051301 248 0.039
regulation of protein modification process GO:0031399 112 0.039
epithelial cell differentiation GO:0030855 322 0.039
endocytosis GO:0006897 310 0.039
positive regulation of intracellular signal transduction GO:1902533 116 0.038
nucleoside catabolic process GO:0009164 112 0.038
regulation of microtubule based process GO:0032886 49 0.038
regulation of cellular catabolic process GO:0031329 157 0.038
neuroblast proliferation GO:0007405 74 0.037
catabolic process GO:0009056 409 0.037
regulation of cellular component movement GO:0051270 42 0.037
embryonic morphogenesis GO:0048598 206 0.037
amine metabolic process GO:0009308 12 0.036
ribonucleoside triphosphate metabolic process GO:0009199 119 0.036
organophosphate metabolic process GO:0019637 195 0.036
glycosyl compound catabolic process GO:1901658 112 0.036
lipid particle organization GO:0034389 7 0.036
response to wounding GO:0009611 94 0.035
single organism biosynthetic process GO:0044711 206 0.035
positive regulation of response to wounding GO:1903036 15 0.035
organic acid metabolic process GO:0006082 103 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.035
regulation of cytoplasmic transport GO:1903649 47 0.034
Human
negative regulation of phosphate metabolic process GO:0045936 45 0.034
nucleotide catabolic process GO:0009166 109 0.034
inorganic ion transmembrane transport GO:0098660 73 0.034
macromolecule catabolic process GO:0009057 161 0.034
tube morphogenesis GO:0035239 191 0.034
heterocycle catabolic process GO:0046700 166 0.034
regulation of apoptotic process GO:0042981 130 0.034
phagocytosis recognition GO:0006910 1 0.034
purine nucleoside catabolic process GO:0006152 112 0.034
regulation of hydrolase activity GO:0051336 97 0.034
neuron projection guidance GO:0097485 241 0.033
guanosine containing compound catabolic process GO:1901069 74 0.033
establishment of planar polarity GO:0001736 87 0.033
epithelium migration GO:0090132 148 0.033
chromatin modification GO:0016568 147 0.033
regulation of nervous system development GO:0051960 248 0.033
autophagic cell death GO:0048102 83 0.033
axon development GO:0061564 297 0.033
neuronal stem cell division GO:0036445 35 0.032
associative learning GO:0008306 65 0.032
Fly
axon guidance GO:0007411 233 0.032
regulation of purine nucleotide metabolic process GO:1900542 62 0.032
positive regulation of transport GO:0051050 92 0.032
Human
calcium ion transport into cytosol GO:0060402 2 0.032
Human
actin filament based process GO:0030029 220 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.031
positive regulation of cell death GO:0010942 69 0.031
dephosphorylation GO:0016311 51 0.031
peptidyl threonine phosphorylation GO:0018107 2 0.031
salivary gland morphogenesis GO:0007435 145 0.031
axonogenesis GO:0007409 290 0.031
purine ribonucleotide metabolic process GO:0009150 145 0.031
negative regulation of nucleic acid templated transcription GO:1903507 240 0.031
organic cyclic compound catabolic process GO:1901361 168 0.031
axon cargo transport GO:0008088 29 0.031
digestive tract development GO:0048565 149 0.031
negative regulation of protein phosphorylation GO:0001933 17 0.031
cellular response to carbohydrate stimulus GO:0071322 4 0.030
protein k48 linked ubiquitination GO:0070936 3 0.030
neural precursor cell proliferation GO:0061351 75 0.030
regulation of nucleotide catabolic process GO:0030811 48 0.030
dopamine biosynthetic process GO:0042416 3 0.030
phagocytosis GO:0006909 215 0.030
tissue migration GO:0090130 155 0.030
cellular response to oxygen containing compound GO:1901701 79 0.030
single organismal cell cell adhesion GO:0016337 45 0.030
regulation of intracellular transport GO:0032386 64 0.029
Human
regulation of behavior GO:0050795 75 0.029
regulation of cell projection organization GO:0031344 92 0.029
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.029
cellular amine metabolic process GO:0044106 12 0.029
single organism catabolic process GO:0044712 228 0.029
protein catabolic process GO:0030163 101 0.029
regulation of cell cycle GO:0051726 291 0.029
single organism cell adhesion GO:0098602 47 0.028
response to ecdysone GO:0035075 34 0.028
protein transport GO:0015031 155 0.028
synaptic growth at neuromuscular junction GO:0051124 119 0.028
transmembrane transport GO:0055085 139 0.028
protein modification by small protein conjugation GO:0032446 79 0.028
hematopoietic or lymphoid organ development GO:0048534 57 0.028
positive regulation of signaling GO:0023056 243 0.028
salivary gland histolysis GO:0035070 88 0.028
negative regulation of signaling GO:0023057 219 0.028
cellular component maintenance GO:0043954 23 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.028
positive regulation of intracellular transport GO:0032388 42 0.028
Human
nucleotide metabolic process GO:0009117 161 0.027
microtubule based movement GO:0007018 51 0.027
response to lipopolysaccharide GO:0032496 4 0.027
regulation of gtp catabolic process GO:0033124 44 0.027
protein modification by small protein conjugation or removal GO:0070647 106 0.027
histolysis GO:0007559 102 0.027
epithelial cell development GO:0002064 274 0.027
regulation of vesicle mediated transport GO:0060627 59 0.027
protein ubiquitination GO:0016567 70 0.026
negative regulation of cellular component organization GO:0051129 108 0.026
gland development GO:0048732 191 0.026
cellular macromolecule localization GO:0070727 220 0.026
cell motility GO:0048870 251 0.026
regulation of endocytosis GO:0030100 37 0.026
cytoskeleton dependent intracellular transport GO:0030705 44 0.026
eye pigment metabolic process GO:0042441 33 0.026
limb development GO:0060173 1 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.025
eye pigment biosynthetic process GO:0006726 32 0.025
glycosyl compound metabolic process GO:1901657 127 0.025
nitrogen compound transport GO:0071705 85 0.025
Mouse
cellular response to chemical stimulus GO:0070887 199 0.025
microtubule based transport GO:0010970 42 0.025
activation of protein kinase activity GO:0032147 12 0.025
cellular response to biotic stimulus GO:0071216 4 0.025
nucleoside phosphate catabolic process GO:1901292 110 0.025
cellular amino acid metabolic process GO:0006520 61 0.024
organic substance catabolic process GO:1901575 308 0.024
response to oxygen containing compound GO:1901700 200 0.024
purine containing compound catabolic process GO:0072523 112 0.024
gtp catabolic process GO:0006184 72 0.024
regulation of developmental growth GO:0048638 174 0.024
hemopoiesis GO:0030097 46 0.024
regulation of phosphorylation GO:0042325 147 0.024
negative regulation of apoptotic process GO:0043066 63 0.024
cytosolic calcium ion homeostasis GO:0051480 11 0.024
Human
immune response regulating signaling pathway GO:0002764 2 0.023
connective tissue development GO:0061448 3 0.023
insulin receptor signaling pathway GO:0008286 25 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
oxoacid metabolic process GO:0043436 103 0.023
macromolecular complex assembly GO:0065003 256 0.023
androgen metabolic process GO:0008209 1 0.023
regulation of dna metabolic process GO:0051052 34 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.022
regulation of homeostatic process GO:0032844 7 0.022
Human Fly
regulation of cysteine type endopeptidase activity GO:2000116 27 0.022
positive regulation of mapk cascade GO:0043410 63 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
rna transport GO:0050658 46 0.022
negative regulation of molecular function GO:0044092 51 0.022
regulation of response to wounding GO:1903034 19 0.022
positive regulation of cell differentiation GO:0045597 64 0.022
hindgut development GO:0061525 58 0.022
regulation of cell proliferation GO:0042127 163 0.022
positive regulation of mitotic cell cycle GO:0045931 34 0.021
ribonucleoside triphosphate catabolic process GO:0009203 108 0.021
acid secretion GO:0046717 1 0.021
Mouse
cellular response to carbon dioxide GO:0071244 2 0.021
endomembrane system organization GO:0010256 119 0.021
regulation of synapse assembly GO:0051963 94 0.021
cognition GO:0050890 141 0.020
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.020
response to external biotic stimulus GO:0043207 293 0.020
photoreceptor cell morphogenesis GO:0008594 18 0.020
salivary gland cell autophagic cell death GO:0035071 83 0.020
eye pigmentation GO:0048069 43 0.020
body morphogenesis GO:0010171 2 0.020
pigment biosynthetic process GO:0046148 36 0.020
limb morphogenesis GO:0035108 1 0.020
regulation of reproductive process GO:2000241 54 0.020
regulation of epithelial cell differentiation GO:0030856 4 0.020
cell recognition GO:0008037 102 0.020
modification dependent protein catabolic process GO:0019941 78 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
cellular protein catabolic process GO:0044257 83 0.020
blastoderm segmentation GO:0007350 159 0.020
cellular response to oxygen levels GO:0071453 30 0.020
regulation of protein phosphorylation GO:0001932 64 0.019
gonad development GO:0008406 50 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
regulation of protein metabolic process GO:0051246 256 0.019
convergent extension GO:0060026 2 0.019
retina development in camera type eye GO:0060041 4 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
response to sterol GO:0036314 34 0.019
protein maturation GO:0051604 71 0.019
anion transport GO:0006820 41 0.019
Mouse
positive regulation of response to external stimulus GO:0032103 44 0.018
protein dephosphorylation GO:0006470 27 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
stem cell proliferation GO:0072089 88 0.018
positive regulation of defense response GO:0031349 59 0.018
hindgut morphogenesis GO:0007442 58 0.018
salivary gland development GO:0007431 162 0.018
rna localization GO:0006403 115 0.018
histone modification GO:0016570 106 0.018
negative regulation of peptidase activity GO:0010466 11 0.018
chromatin organization GO:0006325 207 0.018
spindle organization GO:0007051 253 0.018
establishment of protein localization GO:0045184 163 0.018
ribose phosphate metabolic process GO:0019693 145 0.017
regulation of protein localization GO:0032880 76 0.017
response to organic cyclic compound GO:0014070 89 0.017
dendrite morphogenesis GO:0048813 199 0.017
developmental growth involved in morphogenesis GO:0060560 65 0.017
protein complex assembly GO:0006461 200 0.017
visual perception GO:0007601 9 0.017
Fly
brain development GO:0007420 120 0.017
developmental growth GO:0048589 280 0.017
malpighian tubule morphogenesis GO:0007443 44 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
cellular protein localization GO:0034613 160 0.017
regulation of microtubule based movement GO:0060632 9 0.017
malpighian tubule development GO:0072002 64 0.017
tissue homeostasis GO:0001894 36 0.016
pigment metabolic process involved in pigmentation GO:0043474 33 0.016
intercellular transport GO:0010496 2 0.016
glial cell differentiation GO:0010001 35 0.016
Mouse
dorsal ventral pattern formation GO:0009953 133 0.016
determination of imaginal disc primordium GO:0007445 11 0.016
camera type eye development GO:0043010 4 0.016
intracellular protein transport GO:0006886 104 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
sensory perception of smell GO:0007608 80 0.016
central nervous system development GO:0007417 201 0.016
Mouse
regulation of cellular localization GO:0060341 136 0.016
Human
myotube cell development GO:0014904 3 0.016

trpl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.094
disease of cellular proliferation DOID:14566 0 0.035
nervous system disease DOID:863 0 0.031
sensory system disease DOID:0050155 0 0.028
cancer DOID:162 0 0.022
eye and adnexa disease DOID:1492 0 0.020