Drosophila melanogaster

293 known processes

dsh (Dmel_CG18361)

dishevelled

(Aliases: Dvl,DSH,l(1)10Bd,Dmel\CG18361,l(1)G17,CG1720,l(1)dsh,l(1)G0267,Dsh,CG18361)

dsh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived wing hair organization GO:0035317 45 1.000
ovarian follicle cell development GO:0030707 248 1.000
r3 r4 cell fate commitment GO:0007464 10 1.000
establishment of imaginal disc derived wing hair orientation GO:0001737 24 1.000
morphogenesis of an epithelium GO:0002009 276 0.999
r3 r4 cell differentiation GO:0048056 12 0.999
morphogenesis of a polarized epithelium GO:0001738 93 0.999
cell motility GO:0048870 251 0.998
establishment or maintenance of cell polarity GO:0007163 167 0.998
post embryonic appendage morphogenesis GO:0035120 385 0.998
wing disc morphogenesis GO:0007472 344 0.997
sensory organ morphogenesis GO:0090596 260 0.997
establishment of planar polarity GO:0001736 87 0.996
regulation of cell differentiation GO:0045595 302 0.996
tissue morphogenesis GO:0048729 297 0.996
regulation of neuroblast proliferation GO:1902692 34 0.996
epithelial cell development GO:0002064 274 0.995
actin filament bundle assembly GO:0051017 26 0.994
stem cell development GO:0048864 79 0.994
regulation of cell morphogenesis GO:0022604 163 0.992
imaginal disc derived wing hair site selection GO:0035320 4 0.991
regulation of neuron projection development GO:0010975 69 0.990
Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.990
negative regulation of cell communication GO:0010648 223 0.989
establishment of tissue polarity GO:0007164 87 0.988
neuron projection extension GO:1990138 32 0.987
imaginal disc derived wing morphogenesis GO:0007476 337 0.987
eye photoreceptor cell differentiation GO:0001754 145 0.987
imaginal disc derived appendage development GO:0048737 399 0.986
digestive tract morphogenesis GO:0048546 127 0.985
Worm
hemocyte differentiation GO:0042386 38 0.983
epidermal cell differentiation GO:0009913 51 0.981
actin filament based process GO:0030029 220 0.981
respiratory system development GO:0060541 213 0.980
embryonic organ development GO:0048568 50 0.979
Mouse
stem cell proliferation GO:0072089 88 0.978
positive regulation of transcription dna templated GO:0045893 266 0.978
Human
establishment of proximal distal cell polarity GO:0022606 4 0.977
germarium derived egg chamber formation GO:0007293 101 0.977
regulation of anatomical structure morphogenesis GO:0022603 242 0.977
compound eye photoreceptor fate commitment GO:0001752 36 0.975
epithelium migration GO:0090132 148 0.974
appendage development GO:0048736 401 0.973
head development GO:0060322 135 0.973
Zebrafish
eye morphogenesis GO:0048592 260 0.971
retinal ganglion cell axon guidance GO:0031290 12 0.970
negative regulation of rna metabolic process GO:0051253 251 0.969
positive regulation of macromolecule metabolic process GO:0010604 405 0.968
Human Mouse
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.968
neuron fate commitment GO:0048663 50 0.964
localization of cell GO:0051674 257 0.961
regulation of dendrite morphogenesis GO:0048814 28 0.959
compound eye morphogenesis GO:0001745 249 0.959
regulation of multicellular organismal development GO:2000026 414 0.959
ameboidal type cell migration GO:0001667 151 0.958
establishment of ommatidial planar polarity GO:0042067 49 0.958
skin development GO:0043588 65 0.957
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.954
eye development GO:0001654 323 0.953
axonogenesis GO:0007409 290 0.951
regulation of neurogenesis GO:0050767 158 0.950
Mouse
connective tissue development GO:0061448 3 0.949
eggshell chorion assembly GO:0007306 66 0.949
stem cell differentiation GO:0048863 117 0.946
neuroblast proliferation GO:0007405 74 0.944
tissue migration GO:0090130 155 0.942
regulation of cellular component biogenesis GO:0044087 201 0.940
digestive tract development GO:0048565 149 0.940
Worm
cell fate specification GO:0001708 71 0.940
regulation of nervous system development GO:0051960 248 0.938
Mouse
negative regulation of signal transduction GO:0009968 206 0.936
cellular protein modification process GO:0006464 438 0.935
Human Mouse
chorion containing eggshell formation GO:0007304 105 0.932
photoreceptor cell differentiation GO:0046530 170 0.931
actin filament organization GO:0007015 126 0.931
cell division GO:0051301 248 0.929
Worm
mesoderm development GO:0007498 78 0.928
wnt signaling pathway involved in heart development GO:0003306 3 0.928
embryonic morphogenesis GO:0048598 206 0.928
border follicle cell migration GO:0007298 113 0.927
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.925
photoreceptor cell fate commitment GO:0046552 41 0.925
epithelial cell differentiation GO:0030855 322 0.923
eye photoreceptor cell fate commitment GO:0042706 37 0.918
compound eye photoreceptor cell differentiation GO:0001751 140 0.917
non sensory hair organization GO:0035316 47 0.913
appendage morphogenesis GO:0035107 397 0.912
actin filament bundle organization GO:0061572 28 0.908
cell migration GO:0016477 238 0.905
actin cytoskeleton organization GO:0030036 206 0.904
positive regulation of nucleic acid templated transcription GO:1903508 266 0.904
Human
positive regulation of nervous system development GO:0051962 69 0.901
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.897
Human
compound eye development GO:0048749 307 0.895
axon development GO:0061564 297 0.895
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.893
hair cell differentiation GO:0035315 47 0.890
segmentation GO:0035282 207 0.888
regulation of notch signaling pathway GO:0008593 100 0.888
eye antennal disc development GO:0035214 60 0.884
male gamete generation GO:0048232 201 0.881
regulation of cellular protein metabolic process GO:0032268 243 0.875
Human Mouse
digestive system development GO:0055123 149 0.873
Worm
cell proliferation GO:0008283 299 0.872
regulation of organelle organization GO:0033043 196 0.871
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.870
axon guidance GO:0007411 233 0.870
embryonic pattern specification GO:0009880 174 0.869
cuticle development GO:0042335 86 0.867
dendrite development GO:0016358 204 0.861
Mouse
positive regulation of gene expression GO:0010628 290 0.861
Human
ovarian follicle cell migration GO:0007297 121 0.859
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.854
positive regulation of protein kinase activity GO:0045860 25 0.852
Human Mouse
regulation of cell fate commitment GO:0010453 29 0.849
muscle structure development GO:0061061 224 0.848
columnar cuboidal epithelial cell development GO:0002066 249 0.846
positive regulation of multicellular organismal process GO:0051240 143 0.845
chromatin organization GO:0006325 207 0.841
brain development GO:0007420 120 0.837
Zebrafish
organ formation GO:0048645 39 0.834
cardiovascular system development GO:0072358 82 0.832
tube morphogenesis GO:0035239 191 0.827
Mouse Worm
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.825
central nervous system development GO:0007417 201 0.824
Zebrafish
epithelial cell migration GO:0010631 148 0.823
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.820
regulation of cell shape GO:0008360 113 0.813
chromosome organization GO:0051276 360 0.809
protein modification process GO:0036211 438 0.795
Human Mouse
regulation of axonogenesis GO:0050770 32 0.794
regulation of stem cell proliferation GO:0072091 40 0.791
epidermis development GO:0008544 65 0.788
negative regulation of cell development GO:0010721 62 0.785
regulation of neuron differentiation GO:0045664 103 0.781
Mouse
heart field specification GO:0003128 0 0.773
neuron projection guidance GO:0097485 241 0.772
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.771
blastoderm segmentation GO:0007350 159 0.766
cell cell signaling involved in cell fate commitment GO:0045168 210 0.761
negative regulation of wnt signaling pathway GO:0030178 28 0.757
negative regulation of response to stimulus GO:0048585 258 0.749
developmental growth GO:0048589 280 0.741
epithelial tube morphogenesis GO:0060562 88 0.741
Mouse
tracheal outgrowth open tracheal system GO:0007426 18 0.736
body morphogenesis GO:0010171 2 0.726
Worm
gland development GO:0048732 191 0.725
regionalization GO:0003002 416 0.723
formation of primary germ layer GO:0001704 24 0.721
Worm
dorsal appendage formation GO:0046843 47 0.718
segment polarity determination GO:0007367 25 0.713
positive regulation of biosynthetic process GO:0009891 316 0.712
Human
spermatid differentiation GO:0048515 114 0.703
specification of organ identity GO:0010092 3 0.695
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.695
Human Mouse Worm
cell growth GO:0016049 108 0.691
stem cell division GO:0017145 69 0.691
axon extension GO:0048675 32 0.684
positive regulation of cellular component biogenesis GO:0044089 80 0.679
protein phosphorylation GO:0006468 169 0.679
Human Mouse
non canonical wnt signaling pathway GO:0035567 8 0.658
Human Mouse Worm
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.653
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.648
Human
positive regulation of neurogenesis GO:0050769 41 0.631
Mouse
cuticle pattern formation GO:0035017 27 0.629
endodermal cell fate commitment GO:0001711 3 0.628
Worm
meiotic cell cycle GO:0051321 171 0.618
regulation of cell development GO:0060284 215 0.616
Mouse
organelle fission GO:0048285 340 0.614
negative regulation of rna biosynthetic process GO:1902679 240 0.614
anterior posterior pattern specification GO:0009952 136 0.611
negative regulation of cellular component organization GO:0051129 108 0.607
cell type specific apoptotic process GO:0097285 38 0.602
positive regulation of rna metabolic process GO:0051254 271 0.596
Human
regulation of programmed cell death GO:0043067 152 0.587
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.581
Human
tube development GO:0035295 244 0.577
Human Mouse Worm
mitotic nuclear division GO:0007067 213 0.573
growth GO:0040007 359 0.569
regulation of cell projection organization GO:0031344 92 0.559
Mouse
regulation of cell proliferation GO:0042127 163 0.558
Human
embryonic hemopoiesis GO:0035162 26 0.556
stem cell maintenance GO:0019827 67 0.550
response to organic substance GO:0010033 284 0.544
imaginal disc derived leg morphogenesis GO:0007480 80 0.535
wnt signaling pathway GO:0016055 98 0.535
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.531
establishment of spindle orientation GO:0051294 18 0.529
Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.525
hindgut morphogenesis GO:0007442 58 0.522
endodermal cell differentiation GO:0035987 3 0.516
Worm
skeletal muscle organ development GO:0060538 48 0.514
circulatory system development GO:0072359 82 0.513
renal system development GO:0072001 72 0.512
synaptic transmission GO:0007268 288 0.510
Mouse
morphogenesis of embryonic epithelium GO:0016331 94 0.508
dorsal closure GO:0007391 79 0.503
endocytosis GO:0006897 310 0.500
oocyte development GO:0048599 124 0.496
negative regulation of signaling GO:0023057 219 0.493
stress activated mapk cascade GO:0051403 52 0.490
Human Mouse
positive regulation of cell proliferation GO:0008284 47 0.487
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.479
regulation of protein kinase activity GO:0045859 51 0.476
Human Mouse
eggshell formation GO:0030703 105 0.473
regulation of cell death GO:0010941 173 0.471
positive regulation of wnt signaling pathway GO:0030177 25 0.467
Human Mouse
regulation of anatomical structure size GO:0090066 163 0.465
ommatidial rotation GO:0016318 20 0.464
spermatid development GO:0007286 98 0.454
regulation of cell cycle GO:0051726 291 0.445
Worm
regulation of dendrite development GO:0050773 37 0.441
dna metabolic process GO:0006259 227 0.440
positive regulation of protein modification process GO:0031401 58 0.438
Human Mouse
oocyte microtubule cytoskeleton organization GO:0016325 35 0.432
positive regulation of response to stimulus GO:0048584 323 0.431
Human Mouse
canonical wnt signaling pathway GO:0060070 21 0.429
regulation of protein serine threonine kinase activity GO:0071900 25 0.426
Human Mouse
macromolecular complex assembly GO:0065003 256 0.423
intracellular signal transduction GO:0035556 300 0.423
Human Mouse
aggressive behavior GO:0002118 63 0.421
regulation of organ growth GO:0046620 42 0.419
cell maturation GO:0048469 144 0.412
axis specification GO:0009798 167 0.407
negative regulation of apoptotic signaling pathway GO:2001234 5 0.406
negative regulation of stem cell differentiation GO:2000737 8 0.400
multi organism behavior GO:0051705 175 0.395
Mouse Worm
membrane organization GO:0061024 112 0.394
Mouse
regulation of protein metabolic process GO:0051246 256 0.389
Human Mouse
exocrine system development GO:0035272 162 0.389
determination of left right symmetry GO:0007368 9 0.386
lateral inhibition GO:0046331 206 0.385
determination of bilateral symmetry GO:0009855 13 0.382
positive regulation of developmental process GO:0051094 143 0.376
forebrain development GO:0030900 2 0.370
regulation of growth GO:0040008 233 0.370
regulation of cell fate specification GO:0042659 27 0.369
negative regulation of heart induction GO:1901320 3 0.365
positive regulation of cellular component organization GO:0051130 156 0.363
Mouse
regulation of apoptotic process GO:0042981 130 0.360
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.359
cardiac cell fate commitment GO:0060911 17 0.358
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.357
Human
positive regulation of neuroblast proliferation GO:0002052 7 0.355
regulation of neural precursor cell proliferation GO:2000177 35 0.354
embryonic hindgut morphogenesis GO:0048619 48 0.354
spermatogenesis GO:0007283 200 0.353
regulation of protein modification process GO:0031399 112 0.353
Human Mouse
regulation of response to stress GO:0080134 200 0.352
Human Mouse
negative regulation of biosynthetic process GO:0009890 277 0.352
embryonic development via the syncytial blastoderm GO:0001700 148 0.350
synapse organization GO:0050808 196 0.346
Mouse
malpighian tubule morphogenesis GO:0007443 44 0.344
cellular macromolecule localization GO:0070727 220 0.343
Human Mouse
regulation of canonical wnt signaling pathway GO:0060828 15 0.343
Mouse
regulation of establishment of planar polarity GO:0090175 22 0.342
Human Mouse Worm
apoptotic signaling pathway GO:0097190 27 0.342
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.339
gland morphogenesis GO:0022612 145 0.338
mesenchymal cell differentiation GO:0048762 1 0.337
death GO:0016265 284 0.337
kidney development GO:0001822 3 0.329
negative regulation of cell cell adhesion GO:0022408 8 0.323
negative regulation of gene expression GO:0010629 387 0.316
negative regulation of multicellular organismal process GO:0051241 142 0.311
spinal cord development GO:0021510 1 0.308
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.302
Human
urogenital system development GO:0001655 72 0.300
regulation of map kinase activity GO:0043405 17 0.298
Human Mouse
nephron development GO:0072006 3 0.295
muscle cell differentiation GO:0042692 103 0.294
protein localization GO:0008104 284 0.294
Human Mouse Worm
positive regulation of cell differentiation GO:0045597 64 0.293
Mouse
establishment of cell polarity GO:0030010 40 0.290
developmental growth involved in morphogenesis GO:0060560 65 0.287
proteolysis GO:0006508 192 0.282
Human
oocyte construction GO:0007308 112 0.275
apoptotic process GO:0006915 159 0.275
regulation of cell cycle process GO:0010564 181 0.267
Worm
negative regulation of nucleic acid templated transcription GO:1903507 240 0.266
regulation of actin filament bundle assembly GO:0032231 8 0.263
oocyte differentiation GO:0009994 145 0.262
regulation of protein phosphorylation GO:0001932 64 0.262
Human Mouse
specification of symmetry GO:0009799 13 0.259
gliogenesis GO:0042063 80 0.258
negative regulation of cell differentiation GO:0045596 143 0.256
nuclear division GO:0000280 332 0.255
leg disc morphogenesis GO:0007478 80 0.254
germ cell migration GO:0008354 43 0.253
regulation of sister chromatid cohesion GO:0007063 2 0.251
positive regulation of stem cell proliferation GO:2000648 8 0.250
neuron recognition GO:0008038 101 0.250
notch signaling pathway GO:0007219 120 0.247
actin polymerization or depolymerization GO:0008154 31 0.246
regulation of phosphate metabolic process GO:0019220 210 0.245
Human Mouse
positive regulation of organelle organization GO:0010638 65 0.241
branching morphogenesis of an epithelial tube GO:0048754 45 0.241
establishment of monopolar cell polarity GO:0061162 15 0.241
regulation of actin cytoskeleton organization GO:0032956 42 0.239
neural precursor cell proliferation GO:0061351 75 0.236
proteasomal protein catabolic process GO:0010498 59 0.235
Human
negative regulation of programmed cell death GO:0043069 72 0.234
cellular protein localization GO:0034613 160 0.234
Human Mouse
muscle organ development GO:0007517 127 0.233
sex differentiation GO:0007548 81 0.233
leg disc development GO:0035218 92 0.233
instar larval development GO:0002168 55 0.228
glial cell fate determination GO:0007403 3 0.226
muscle tissue development GO:0060537 30 0.226
dorsal closure elongation of leading edge cells GO:0007394 10 0.226
anterior posterior axis specification GO:0009948 109 0.224
germarium derived female germ line cyst formation GO:0030727 42 0.223
heart induction GO:0003129 3 0.223
chromosome segregation GO:0007059 157 0.222
regulation of organ morphogenesis GO:2000027 78 0.222
camera type eye morphogenesis GO:0048593 2 0.222
eye antennal disc morphogenesis GO:0007455 34 0.221
organic substance catabolic process GO:1901575 308 0.215
Human
dendrite morphogenesis GO:0048813 199 0.210
Mouse
phosphorylation GO:0016310 294 0.208
Human Mouse
protein catabolic process GO:0030163 101 0.208
Human
ovarian follicle cell stalk formation GO:0030713 17 0.205
organonitrogen compound metabolic process GO:1901564 318 0.205
programmed cell death GO:0012501 257 0.203
cellular protein complex assembly GO:0043623 71 0.203
biological adhesion GO:0022610 138 0.200
post embryonic hemopoiesis GO:0035166 17 0.199
regulation of phosphorylation GO:0042325 147 0.199
Human Mouse
jnk cascade GO:0007254 50 0.194
Human Mouse
dorsal ventral pattern formation GO:0009953 133 0.194
r7 cell differentiation GO:0045466 43 0.193
regulation of heart morphogenesis GO:2000826 3 0.193
macromolecule catabolic process GO:0009057 161 0.192
Human
negative regulation of mapk cascade GO:0043409 23 0.191
malpighian tubule tip cell differentiation GO:0061382 9 0.191
cell projection assembly GO:0030031 94 0.190
signal transduction by phosphorylation GO:0023014 107 0.190
Human Mouse
neuromuscular junction development GO:0007528 149 0.190
Mouse
negative regulation of notch signaling pathway GO:0045746 41 0.186
limb development GO:0060173 1 0.183
germ line cyst formation GO:0048134 44 0.183
negative regulation of cell proliferation GO:0008285 69 0.183
negative regulation of developmental process GO:0051093 201 0.183
negative regulation of cellular biosynthetic process GO:0031327 277 0.182
negative regulation of neurogenesis GO:0050768 53 0.182
regulation of cellular component size GO:0032535 98 0.181
regulation of actin filament based process GO:0032970 42 0.180
positive regulation of transferase activity GO:0051347 26 0.179
Human Mouse
open tracheal system development GO:0007424 204 0.178
morphogenesis of a branching epithelium GO:0061138 45 0.177
regulation of jnk cascade GO:0046328 40 0.177
Human Mouse
periodic partitioning GO:0007365 29 0.174
meiosis i GO:0007127 59 0.171
positive regulation of signaling GO:0023056 243 0.169
Human Mouse
establishment of epithelial cell apical basal polarity GO:0045198 10 0.168
ubiquitin dependent protein catabolic process GO:0006511 78 0.167
Human
regulation of neuron death GO:1901214 26 0.166
cardioblast differentiation GO:0010002 20 0.165
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.164
telencephalon development GO:0021537 2 0.163
cell junction organization GO:0034330 57 0.163
cell fate determination involved in pattern specification GO:0060582 19 0.162
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.160
negative regulation of cell death GO:0060548 81 0.160
regulation of stem cell differentiation GO:2000736 14 0.160
mitotic cytokinesis GO:0000281 50 0.159
positive regulation of cell communication GO:0010647 250 0.158
Human Mouse
cardiocyte differentiation GO:0035051 29 0.154
branching involved in open tracheal system development GO:0060446 45 0.152
covalent chromatin modification GO:0016569 106 0.152
regulation of intracellular signal transduction GO:1902531 236 0.150
Human Mouse
regulation of proteolysis GO:0030162 87 0.150
Human
histone modification GO:0016570 106 0.148
carbohydrate derivative metabolic process GO:1901135 217 0.148
cell adhesion GO:0007155 136 0.147
chaeta development GO:0022416 97 0.147
modification dependent protein catabolic process GO:0019941 78 0.145
Human
gonad development GO:0008406 50 0.145
multicellular organismal reproductive behavior GO:0033057 110 0.144
Worm
protein localization to organelle GO:0033365 82 0.143
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.143
Human
cuticle pigmentation GO:0048067 22 0.143
regulation of actin filament polymerization GO:0030833 25 0.143
embryonic organ morphogenesis GO:0048562 5 0.143
Mouse
muscle fiber development GO:0048747 12 0.141
embryonic digestive tract morphogenesis GO:0048557 4 0.141
regulation of dna metabolic process GO:0051052 34 0.141
positive regulation of rna biosynthetic process GO:1902680 266 0.140
Human
cell junction assembly GO:0034329 42 0.139
regulation of apoptotic signaling pathway GO:2001233 10 0.138
regulation of imaginal disc growth GO:0045570 26 0.137
embryo development ending in birth or egg hatching GO:0009792 152 0.137
regulation of cytoskeleton organization GO:0051493 89 0.137
mating behavior GO:0007617 106 0.136
positive regulation of hh target transcription factor activity GO:0007228 5 0.135
positive regulation of cell development GO:0010720 61 0.134
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.132
Human Mouse
developmental cell growth GO:0048588 52 0.131
limb morphogenesis GO:0035108 1 0.129
inter male aggressive behavior GO:0002121 60 0.128
chromatin modification GO:0016568 147 0.126
mesenchymal cell development GO:0014031 1 0.126
negative regulation of protein metabolic process GO:0051248 85 0.124
Human Mouse
positive regulation of map kinase activity GO:0043406 11 0.124
Human Mouse
homeostatic process GO:0042592 199 0.124
dendrite self avoidance GO:0070593 8 0.124
positive regulation of neuron differentiation GO:0045666 26 0.123
Mouse
protein complex biogenesis GO:0070271 201 0.122
regulation of wnt signaling pathway GO:0030111 68 0.121
Human Mouse
regulation of protein ubiquitination GO:0031396 22 0.121
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.120
neuroblast division GO:0055057 35 0.118
neuron death GO:0070997 27 0.118
convergent extension GO:0060026 2 0.117
Zebrafish Mouse
spindle organization GO:0007051 253 0.117
Worm
wound healing GO:0042060 75 0.116
establishment of organelle localization GO:0051656 122 0.114
Worm
vesicle mediated transport GO:0016192 381 0.113
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.113
Human
regulation of mapk cascade GO:0043408 92 0.113
Human Mouse
renal tubule development GO:0061326 64 0.113
negative regulation of cardioblast differentiation GO:0051892 7 0.112
hematopoietic or lymphoid organ development GO:0048534 57 0.111
asymmetric cell division GO:0008356 37 0.111
Worm
crystal cell differentiation GO:0042688 7 0.111
anatomical structure homeostasis GO:0060249 97 0.111
positive regulation of phosphorylation GO:0042327 87 0.111
Human Mouse
organelle localization GO:0051640 148 0.111
Worm
negative regulation of molecular function GO:0044092 51 0.109
Human
positive regulation of developmental growth GO:0048639 62 0.108
cilium morphogenesis GO:0060271 39 0.108
negative regulation of cellular catabolic process GO:0031330 34 0.108
protein maturation GO:0051604 71 0.105
response to wounding GO:0009611 94 0.105
striated muscle tissue development GO:0014706 27 0.104
regulation of mitosis GO:0007088 56 0.104
second mitotic wave involved in compound eye morphogenesis GO:0016330 7 0.104
compound eye photoreceptor development GO:0042051 78 0.104
mapk cascade GO:0000165 107 0.102
Human Mouse
protein transport GO:0015031 155 0.101
hemocyte migration GO:0035099 19 0.101
regulation of synapse structure and activity GO:0050803 128 0.100
initiation of dorsal closure GO:0007392 12 0.099
meiotic nuclear division GO:0007126 151 0.098
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.098
nucleoside metabolic process GO:0009116 127 0.097
somatic stem cell maintenance GO:0035019 14 0.097
compound eye retinal cell programmed cell death GO:0046667 23 0.095
sensory organ precursor cell fate determination GO:0016360 19 0.095
methylation GO:0032259 47 0.095
anterior posterior axis specification embryo GO:0008595 103 0.095
regulation of actin polymerization or depolymerization GO:0008064 27 0.094
axis elongation GO:0003401 3 0.094
Zebrafish
small molecule metabolic process GO:0044281 305 0.094
asymmetric neuroblast division resulting in ganglion mother cell formation GO:0055060 2 0.094
embryonic axis specification GO:0000578 107 0.093
establishment of mitotic spindle localization GO:0040001 17 0.093
Worm
organic substance transport GO:0071702 257 0.093
regulation of developmental growth GO:0048638 174 0.093
ras protein signal transduction GO:0007265 88 0.092
imaginal disc derived leg segmentation GO:0036011 26 0.092
camera type eye development GO:0043010 4 0.092
regulation of cardioblast cell fate specification GO:0042686 8 0.092
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.091
enzyme linked receptor protein signaling pathway GO:0007167 179 0.091
gastrulation GO:0007369 70 0.091
Worm
negative regulation of transcription dna templated GO:0045892 237 0.090
carbohydrate derivative biosynthetic process GO:1901137 85 0.090
signal transduction downstream of smoothened GO:0007227 5 0.089
extracellular structure organization GO:0043062 46 0.089
stress activated protein kinase signaling cascade GO:0031098 55 0.089
Human Mouse
negative regulation of gene expression epigenetic GO:0045814 77 0.088
protein modification by small protein conjugation GO:0032446 79 0.088
positive regulation of signal transduction GO:0009967 223 0.087
Human Mouse
regulation of gene expression epigenetic GO:0040029 128 0.086
positive regulation of cell cycle process GO:0090068 28 0.086
reproductive behavior GO:0019098 122 0.086
Worm
tripartite regional subdivision GO:0007351 103 0.085
positive regulation of cellular biosynthetic process GO:0031328 316 0.084
Human
negative regulation of protein processing GO:0010955 31 0.083
somatic stem cell division GO:0048103 37 0.083
morphogenesis of a branching structure GO:0001763 45 0.082
regulation of cell adhesion GO:0030155 27 0.081
establishment of mitotic spindle orientation GO:0000132 13 0.081
Worm
regulation of compound eye photoreceptor development GO:0045314 12 0.081
regulation of localization GO:0032879 275 0.080
Worm
cellular component assembly involved in morphogenesis GO:0010927 151 0.080
muscle tissue morphogenesis GO:0060415 2 0.080
response to growth factor GO:0070848 31 0.080
establishment of spindle localization GO:0051293 22 0.079
Worm

dsh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
familial meningioma DOID:4586 0 0.106
nervous system cancer DOID:3093 0 0.106
central nervous system cancer DOID:3620 0 0.106
cancer DOID:162 0 0.106
disease of cellular proliferation DOID:14566 0 0.106
organ system cancer DOID:0050686 0 0.106
meningioma DOID:3565 0 0.106
disease of anatomical entity DOID:7 0 0.096