Drosophila melanogaster

107 known processes

Sema-1a (Dmel_CG18405)

CG18405 gene product from transcript CG18405-RD

(Aliases: BcDNA:RE36155,Fas-IV,d-semaI,sema1a,SemaI,D-Sema-I,CG18405,D-SemaI,FasIV,sema-1a,sema-I,Sema 1a,Sema1A,D-semaI,D-Sema I,D-Sema 1a,CT26404,d-sema I,Sema-I,Dmel\CG18405,Dsema-I,Dsema 1a,sema 1a,Sema1a,sema,l(2)k13702)

Sema-1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axonogenesis GO:0007409 290 1.000
neuron projection guidance GO:0097485 241 1.000
axon development GO:0061564 297 1.000
taxis GO:0042330 304 1.000
motor neuron axon guidance GO:0008045 58 1.000
axon guidance GO:0007411 233 1.000
chemotaxis GO:0006935 249 1.000
dendrite guidance GO:0070983 21 0.999
Fly
photoreceptor cell axon guidance GO:0072499 23 0.993
regulation of cell development GO:0060284 215 0.978
positive regulation of nervous system development GO:0051962 69 0.977
Mouse
regulation of photoreceptor cell axon guidance GO:2000289 5 0.974
regulation of axon extension involved in axon guidance GO:0048841 4 0.969
dendrite development GO:0016358 204 0.969
regulation of cell differentiation GO:0045595 302 0.969
retinal ganglion cell axon guidance GO:0031290 12 0.967
olfactory bulb axon guidance GO:0071678 3 0.966
Fly
central nervous system development GO:0007417 201 0.957
dorsal ventral axon guidance GO:0033563 2 0.933
regulation of nervous system development GO:0051960 248 0.918
synapse assembly GO:0007416 143 0.906
regulation of axon guidance GO:1902667 10 0.900
dendrite morphogenesis GO:0048813 199 0.889
regulation of cellular component biogenesis GO:0044087 201 0.883
positive regulation of cell migration GO:0030335 2 0.873
Mouse
regulation of multicellular organismal development GO:2000026 414 0.864
regulation of behavior GO:0050795 75 0.853
synaptic growth at neuromuscular junction GO:0051124 119 0.843
axon midline choice point recognition GO:0016199 26 0.835
positive regulation of axonogenesis GO:0050772 2 0.827
regulation of neurogenesis GO:0050767 158 0.815
negative regulation of cell communication GO:0010648 223 0.809
axon extension involved in axon guidance GO:0048846 10 0.800
appendage development GO:0048736 401 0.793
axon target recognition GO:0007412 16 0.789
regulation of localization GO:0032879 275 0.783
cell migration GO:0016477 238 0.756
Mouse
axon choice point recognition GO:0016198 26 0.742
protein modification process GO:0036211 438 0.739
positive regulation of transport GO:0051050 92 0.727
embryonic morphogenesis GO:0048598 206 0.724
establishment of localization in cell GO:0051649 402 0.698
positive regulation of response to stimulus GO:0048584 323 0.690
regulation of neuron differentiation GO:0045664 103 0.683
organic substance catabolic process GO:1901575 308 0.682
neuron recognition GO:0008038 101 0.648
circulatory system development GO:0072359 82 0.633
axonal defasciculation GO:0007414 12 0.626
neuromuscular junction development GO:0007528 149 0.625
stem cell differentiation GO:0048863 117 0.623
positive regulation of neuron differentiation GO:0045666 26 0.622
neuron projection extension GO:1990138 32 0.621
growth GO:0040007 359 0.618
synapse organization GO:0050808 196 0.609
regulation of dendrite development GO:0050773 37 0.604
hindbrain development GO:0030902 2 0.581
developmental growth GO:0048589 280 0.577
negative regulation of multicellular organismal process GO:0051241 142 0.575
regulation of neuron projection development GO:0010975 69 0.522
cellular protein modification process GO:0006464 438 0.504
negative regulation of phosphorylation GO:0042326 35 0.504
negative regulation of response to stimulus GO:0048585 258 0.503
regulation of axonogenesis GO:0050770 32 0.498
protein phosphorylation GO:0006468 169 0.483
regulation of synapse organization GO:0050807 110 0.473
axon extension GO:0048675 32 0.470
localization of cell GO:0051674 257 0.464
Mouse
gastrulation GO:0007369 70 0.462
head development GO:0060322 135 0.460
heart development GO:0007507 82 0.457
regulation of chemotaxis GO:0050920 12 0.448
regulation of synapse structure and activity GO:0050803 128 0.445
anterior commissure morphogenesis GO:0021960 2 0.436
phosphorylation GO:0016310 294 0.433
regulation of cellular component movement GO:0051270 42 0.428
muscle structure development GO:0061061 224 0.428
positive regulation of neurogenesis GO:0050769 41 0.416
Mouse
regulation of phosphorylation GO:0042325 147 0.412
regulation of dendrite morphogenesis GO:0048814 28 0.411
regulation of transport GO:0051049 181 0.407
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.407
positive regulation of axon guidance GO:1902669 1 0.399
camera type eye development GO:0043010 4 0.392
brain development GO:0007420 120 0.388
regulation of response to external stimulus GO:0032101 115 0.386
eye morphogenesis GO:0048592 260 0.368
regulation of developmental growth GO:0048638 174 0.367
cell death GO:0008219 279 0.359
gliogenesis GO:0042063 80 0.351
locomotory behavior GO:0007626 176 0.348
regulation of phosphorus metabolic process GO:0051174 210 0.344
cardiovascular system development GO:0072358 82 0.343
ventral cord development GO:0007419 16 0.338
regulation of cell motility GO:2000145 23 0.335
Mouse
sensory organ morphogenesis GO:0090596 260 0.327
regulation of cellular localization GO:0060341 136 0.324
positive regulation of cell communication GO:0010647 250 0.324
stem cell development GO:0048864 79 0.322
circulatory system process GO:0003013 37 0.318
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.318
positive regulation of behavior GO:0048520 19 0.315
positive regulation of cellular component biogenesis GO:0044089 80 0.310
forebrain development GO:0030900 2 0.306
positive regulation of multicellular organismal process GO:0051240 143 0.304
Mouse
negative regulation of developmental process GO:0051093 201 0.302
telencephalon development GO:0021537 2 0.299
cell projection assembly GO:0030031 94 0.296
synaptic transmission GO:0007268 288 0.291
mapk cascade GO:0000165 107 0.288
spinal cord development GO:0021510 1 0.287
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.284
regulation of cell projection organization GO:0031344 92 0.284
regulation of molecular function GO:0065009 217 0.281
regulation of synapse assembly GO:0051963 94 0.278
positive regulation of cell development GO:0010720 61 0.276
Mouse
multi multicellular organism process GO:0044706 123 0.274
cell motility GO:0048870 251 0.264
Mouse
regulation of vesicle mediated transport GO:0060627 59 0.263
transcription from rna polymerase ii promoter GO:0006366 368 0.262
tube development GO:0035295 244 0.260
regulation of system process GO:0044057 36 0.257
regulation of growth GO:0040008 233 0.246
positive regulation of signal transduction GO:0009967 223 0.243
multi organism behavior GO:0051705 175 0.236
single organism catabolic process GO:0044712 228 0.235
regulation of secretion GO:0051046 44 0.231
epithelial cell development GO:0002064 274 0.230
gland development GO:0048732 191 0.229
Fly
filopodium assembly GO:0046847 33 0.228
positive regulation of developmental process GO:0051094 143 0.228
Mouse
glial cell differentiation GO:0010001 35 0.228
regulation of mapk cascade GO:0043408 92 0.227
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.226
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.225
regulation of anatomical structure size GO:0090066 163 0.215
morphogenesis of a branching structure GO:0001763 45 0.215
eye photoreceptor cell differentiation GO:0001754 145 0.212
positive regulation of transcription dna templated GO:0045893 266 0.212
positive regulation of secretion GO:0051047 22 0.209
regulation of synaptic transmission GO:0050804 69 0.209
negative regulation of phosphorus metabolic process GO:0010563 45 0.206
positive regulation of cell motility GO:2000147 3 0.206
Mouse
retrograde axon cargo transport GO:0008090 9 0.203
cellular macromolecular complex assembly GO:0034622 153 0.202
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.198
positive regulation of axon extension GO:0045773 2 0.190
regulation of phosphate metabolic process GO:0019220 210 0.184
regulation of cell migration GO:0030334 22 0.182
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.181
photoreceptor cell differentiation GO:0046530 170 0.179
regulation of neuronal synaptic plasticity GO:0048168 8 0.178
substrate dependent cell migration GO:0006929 3 0.178
regulation of protein phosphorylation GO:0001932 64 0.175
cell maturation GO:0048469 144 0.174
negative regulation of rna metabolic process GO:0051253 251 0.170
positive regulation of signaling GO:0023056 243 0.169
striated muscle cell development GO:0055002 50 0.168
regulation of cellular response to stress GO:0080135 89 0.167
negative regulation of synapse assembly GO:0051964 39 0.164
positive regulation of jun kinase activity GO:0043507 4 0.162
negative regulation of programmed cell death GO:0043069 72 0.161
developmental growth involved in morphogenesis GO:0060560 65 0.158
negative regulation of phosphate metabolic process GO:0045936 45 0.157
detection of external stimulus GO:0009581 66 0.157
neuron migration GO:0001764 5 0.157
Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.155
immune system development GO:0002520 57 0.153
secretion GO:0046903 109 0.151
positive regulation of synapse assembly GO:0051965 29 0.151
negative regulation of protein phosphorylation GO:0001933 17 0.150
developmental maturation GO:0021700 172 0.147
photoreceptor cell development GO:0042461 96 0.147
regulation of response to stress GO:0080134 200 0.145
single organism cellular localization GO:1902580 180 0.142
multicellular organismal reproductive behavior GO:0033057 110 0.141
death GO:0016265 284 0.140
regulation of cell death GO:0010941 173 0.140
compound eye photoreceptor development GO:0042051 78 0.138
regulation of immune system process GO:0002682 176 0.138
regulation of anatomical structure morphogenesis GO:0022603 242 0.137
adult locomotory behavior GO:0008344 76 0.137
Fly
negative regulation of gene expression GO:0010629 387 0.136
positive regulation of response to external stimulus GO:0032103 44 0.136
digestive system development GO:0055123 149 0.136
positive regulation of protein complex assembly GO:0031334 22 0.134
positive regulation of cellular biosynthetic process GO:0031328 316 0.132
extracellular matrix organization GO:0030198 32 0.131
positive regulation of rna biosynthetic process GO:1902680 266 0.131
regulation of intracellular signal transduction GO:1902531 236 0.131
regulation of ion transport GO:0043269 39 0.129
negative regulation of cell differentiation GO:0045596 143 0.128
cell activation GO:0001775 9 0.128
compound eye photoreceptor cell differentiation GO:0001751 140 0.127
organonitrogen compound metabolic process GO:1901564 318 0.127
catabolic process GO:0009056 409 0.126
single organism intracellular transport GO:1902582 207 0.125
signal release GO:0023061 49 0.125
glial cell migration GO:0008347 31 0.125
signal transduction by phosphorylation GO:0023014 107 0.124
renal system development GO:0072001 72 0.123
digestive tract development GO:0048565 149 0.123
intracellular signal transduction GO:0035556 300 0.123
regulation of cell proliferation GO:0042127 163 0.123
vesicle mediated transport GO:0016192 381 0.122
eye development GO:0001654 323 0.122
regulation of locomotion GO:0040012 42 0.121
oxoacid metabolic process GO:0043436 103 0.121
regulation of catalytic activity GO:0050790 185 0.120
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.118
dna recombination GO:0006310 32 0.117
activation of jun kinase activity GO:0007257 3 0.117
central nervous system projection neuron axonogenesis GO:0021952 6 0.113
protein localization GO:0008104 284 0.113
cell junction assembly GO:0034329 42 0.112
positive regulation of phosphorylation GO:0042327 87 0.111
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.110
learning or memory GO:0007611 141 0.110
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.109
positive regulation of biosynthetic process GO:0009891 316 0.108
erbb signaling pathway GO:0038127 58 0.108
blood circulation GO:0008015 26 0.103
establishment of protein localization GO:0045184 163 0.103
regulation of cytoskeleton organization GO:0051493 89 0.101
secretion by cell GO:0032940 101 0.100
positive regulation of neuron projection development GO:0010976 14 0.099
protein modification by small protein conjugation or removal GO:0070647 106 0.099
negative regulation of growth GO:0045926 84 0.099
regulation of programmed cell death GO:0043067 152 0.098
reproductive behavior GO:0019098 122 0.097
urogenital system development GO:0001655 72 0.096
glial cell development GO:0021782 27 0.096
positive regulation of macromolecule metabolic process GO:0010604 405 0.096
oocyte differentiation GO:0009994 145 0.095
regulation of axon extension GO:0030516 8 0.094
ras protein signal transduction GO:0007265 88 0.094
morphogenesis of an epithelium GO:0002009 276 0.093
cellular catabolic process GO:0044248 372 0.092
eye photoreceptor cell development GO:0042462 81 0.092
stem cell division GO:0017145 69 0.092
negative regulation of developmental growth GO:0048640 64 0.090
embryonic organ development GO:0048568 50 0.089
regulation of secretion by cell GO:1903530 39 0.088
membrane organization GO:0061024 112 0.088
positive regulation of secretion by cell GO:1903532 20 0.088
positive regulation of phosphorus metabolic process GO:0010562 139 0.088
response to wounding GO:0009611 94 0.087
regionalization GO:0003002 416 0.087
striated muscle cell differentiation GO:0051146 90 0.086
apoptotic process GO:0006915 159 0.085
immune response GO:0006955 246 0.085
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.084
dephosphorylation GO:0016311 51 0.084
neuron fate commitment GO:0048663 50 0.083
single organism carbohydrate metabolic process GO:0044723 72 0.083
organic acid metabolic process GO:0006082 103 0.081
cellular response to extracellular stimulus GO:0031668 64 0.080
enzyme linked receptor protein signaling pathway GO:0007167 179 0.079
negative regulation of cellular metabolic process GO:0031324 382 0.079
negative regulation of catalytic activity GO:0043086 42 0.079
tube morphogenesis GO:0035239 191 0.079
positive regulation of cell differentiation GO:0045597 64 0.078
Mouse
positive regulation of growth GO:0045927 75 0.077
positive regulation of nucleic acid templated transcription GO:1903508 266 0.075
negative regulation of epithelial cell proliferation GO:0050680 4 0.074
organic substance transport GO:0071702 257 0.074
r7 cell differentiation GO:0045466 43 0.074
protein complex biogenesis GO:0070271 201 0.074
regulation of apoptotic process GO:0042981 130 0.073
oviposition GO:0018991 19 0.073
cellular amino acid metabolic process GO:0006520 61 0.072
single organism membrane organization GO:0044802 93 0.072
collateral sprouting GO:0048668 3 0.072
kidney development GO:0001822 3 0.072
synaptic target recognition GO:0008039 45 0.071
immune system process GO:0002376 347 0.071
negative regulation of signaling GO:0023057 219 0.070
regulation of stress activated mapk cascade GO:0032872 41 0.070
macromolecule catabolic process GO:0009057 161 0.070
regulation of protein metabolic process GO:0051246 256 0.068
regulation of transferase activity GO:0051338 58 0.068
positive regulation of molecular function GO:0044093 136 0.068
regulation of map kinase activity GO:0043405 17 0.068
cell fate specification GO:0001708 71 0.068
mesenchymal cell development GO:0014031 1 0.067
muscle cell development GO:0055001 50 0.067
cell junction organization GO:0034330 57 0.067
extrinsic apoptotic signaling pathway GO:0097191 1 0.066
regulation of kinase activity GO:0043549 53 0.066
imaginal disc derived appendage development GO:0048737 399 0.064
tor signaling GO:0031929 32 0.064
programmed cell death GO:0012501 257 0.064
positive regulation of developmental growth GO:0048639 62 0.063
negative regulation of axon extension GO:0030517 3 0.063
positive regulation of exocytosis GO:0045921 4 0.063
inositol lipid mediated signaling GO:0048017 4 0.063
macromolecular complex assembly GO:0065003 256 0.062
protein complex assembly GO:0006461 200 0.060
regulation of bmp signaling pathway GO:0030510 23 0.060
regulation of multi organism process GO:0043900 131 0.060
semaphorin plexin signaling pathway GO:0071526 4 0.060
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.059
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.059
stress activated mapk cascade GO:0051403 52 0.059
cell cell adhesion GO:0098609 26 0.058
regulation of protein kinase activity GO:0045859 51 0.058
cell proliferation GO:0008283 299 0.058
appendage morphogenesis GO:0035107 397 0.058
intracellular transport GO:0046907 228 0.058
single organism behavior GO:0044708 391 0.058
Fly
neuromuscular synaptic transmission GO:0007274 67 0.058
protein catabolic process GO:0030163 101 0.057
jnk cascade GO:0007254 50 0.057
regulation of epithelial cell migration GO:0010632 12 0.056
regulation of cell size GO:0008361 63 0.056
stress activated protein kinase signaling cascade GO:0031098 55 0.056
negative regulation of signal transduction GO:0009968 206 0.055
neuron death GO:0070997 27 0.055
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.054
establishment of organelle localization GO:0051656 122 0.054
central complex development GO:0048036 9 0.054
mitotic cell cycle phase transition GO:0044772 138 0.054
cell adhesion GO:0007155 136 0.053
negative regulation of protein metabolic process GO:0051248 85 0.053
response to peptide hormone GO:0043434 29 0.053
central nervous system neuron differentiation GO:0021953 8 0.052
negative regulation of biosynthetic process GO:0009890 277 0.051
phenol containing compound metabolic process GO:0018958 57 0.051
regulation of cellular protein metabolic process GO:0032268 243 0.051
carboxylic acid metabolic process GO:0019752 92 0.051
regulation of sequestering of calcium ion GO:0051282 3 0.051
regulation of protein modification process GO:0031399 112 0.051
negative regulation of cellular biosynthetic process GO:0031327 277 0.050
regulation of blood circulation GO:1903522 21 0.050
developmental cell growth GO:0048588 52 0.050
epithelial cell migration GO:0010631 148 0.050
regulation of protein transport GO:0051223 57 0.050
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.049
regulation of protein complex assembly GO:0043254 42 0.049
rho protein signal transduction GO:0007266 14 0.049
regulation of immune response GO:0050776 118 0.049
regulation of intracellular transport GO:0032386 64 0.049
regulation of actin filament based process GO:0032970 42 0.048
response to abiotic stimulus GO:0009628 341 0.048
Fly
regulation of r7 cell differentiation GO:0045676 15 0.048
erk1 and erk2 cascade GO:0070371 39 0.047
positive regulation of bmp signaling pathway GO:0030513 5 0.047
protein transport GO:0015031 155 0.047
cellular macromolecule localization GO:0070727 220 0.047
meiotic nuclear division GO:0007126 151 0.047
epithelial cell differentiation GO:0030855 322 0.047
negative regulation of mapk cascade GO:0043409 23 0.047
negative regulation of cellular protein metabolic process GO:0032269 85 0.047
positive regulation of lipid metabolic process GO:0045834 4 0.046
positive regulation of cellular component organization GO:0051130 156 0.046
chemical homeostasis GO:0048878 92 0.046
response to oxygen containing compound GO:1901700 200 0.046
negative regulation of epithelial cell migration GO:0010633 1 0.046
negative regulation of neurogenesis GO:0050768 53 0.046
r7 cell development GO:0045467 14 0.046
endocytosis GO:0006897 310 0.045
kidney epithelium development GO:0072073 3 0.045
small molecule metabolic process GO:0044281 305 0.045
small gtpase mediated signal transduction GO:0007264 88 0.045
imaginal disc derived wing morphogenesis GO:0007476 337 0.045
cellular response to chemical stimulus GO:0070887 199 0.045
regulation of membrane potential GO:0042391 35 0.045
regulation of cell growth GO:0001558 43 0.044
bmp signaling pathway GO:0030509 27 0.044
cell division GO:0051301 248 0.044
oocyte axis specification GO:0007309 108 0.044
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.044
digestive tract morphogenesis GO:0048546 127 0.043
cell growth GO:0016049 108 0.043
embryo development ending in birth or egg hatching GO:0009792 152 0.042
Fly
negative regulation of neuron differentiation GO:0045665 16 0.042
microtubule based transport GO:0010970 42 0.042
embryonic development via the syncytial blastoderm GO:0001700 148 0.041
Fly
oocyte fate determination GO:0030716 27 0.041
negative regulation of neuromuscular synaptic transmission GO:1900074 7 0.041
cellular homeostasis GO:0019725 80 0.041
regulation of neuron apoptotic process GO:0043523 16 0.040
g protein coupled receptor signaling pathway GO:0007186 136 0.040
cardiocyte differentiation GO:0035051 29 0.040
negative regulation of kinase activity GO:0033673 16 0.040
learning GO:0007612 75 0.040
muscle organ development GO:0007517 127 0.040
positive regulation of immune response GO:0050778 63 0.039
neurological system process GO:0050877 358 0.039
cellular protein complex disassembly GO:0043624 35 0.039
regulation of hydrolase activity GO:0051336 97 0.038
regulation of jnk cascade GO:0046328 40 0.037
dorsal ventral pattern formation GO:0009953 133 0.037
regulation of synaptic plasticity GO:0048167 14 0.037
regulation of production of molecular mediator of immune response GO:0002700 44 0.037
dorsal ventral axis specification GO:0009950 66 0.037
response to radiation GO:0009314 155 0.037
Fly
positive regulation of nucleoside metabolic process GO:0045979 47 0.037
carbohydrate derivative metabolic process GO:1901135 217 0.036
peptidyl amino acid modification GO:0018193 105 0.036
glycoprotein metabolic process GO:0009100 41 0.036
germ cell migration GO:0008354 43 0.036
regulation of small gtpase mediated signal transduction GO:0051056 93 0.035
negative regulation of cellular component organization GO:0051129 108 0.035
adult chitin containing cuticle pigmentation GO:0048085 16 0.035
response to alcohol GO:0097305 95 0.035
peptidyl threonine phosphorylation GO:0018107 2 0.035
maintenance of presynaptic active zone structure GO:0048790 8 0.035
positive regulation of catalytic activity GO:0043085 118 0.034
microtubule based movement GO:0007018 51 0.034
neuron fate specification GO:0048665 12 0.034
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.033
cell chemotaxis GO:0060326 6 0.033
intracellular protein transport GO:0006886 104 0.033
response to organic substance GO:0010033 284 0.032
homeostatic process GO:0042592 199 0.032
hemopoiesis GO:0030097 46 0.032
regulation of protein secretion GO:0050708 13 0.032
response to nitrogen compound GO:1901698 90 0.032
cellular protein complex assembly GO:0043623 71 0.032
actin filament organization GO:0007015 126 0.032
amine metabolic process GO:0009308 12 0.031
metal ion transport GO:0030001 74 0.031
respiratory system development GO:0060541 213 0.031
extracellular structure organization GO:0043062 46 0.031
nephron epithelium development GO:0072009 3 0.031
adult behavior GO:0030534 137 0.031
Fly
renal filtration cell differentiation GO:0061318 12 0.031
epithelial tube morphogenesis GO:0060562 88 0.031
cytoplasmic transport GO:0016482 130 0.031
open tracheal system development GO:0007424 204 0.030
polysaccharide metabolic process GO:0005976 11 0.030
protein modification by small protein conjugation GO:0032446 79 0.030
regulation of embryonic pattern specification GO:1902875 27 0.030
response to organonitrogen compound GO:0010243 75 0.030
positive regulation of cellular component movement GO:0051272 11 0.030
Mouse
cognition GO:0050890 141 0.030
cell recognition GO:0008037 102 0.029
cell cell junction assembly GO:0007043 38 0.029
response to endogenous stimulus GO:0009719 119 0.029
positive regulation of apoptotic signaling pathway GO:2001235 4 0.029
negative regulation of protein modification process GO:0031400 29 0.029
axonal fasciculation GO:0007413 12 0.029
actin polymerization or depolymerization GO:0008154 31 0.029
positive regulation of rna metabolic process GO:0051254 271 0.029
positive regulation of cellular amine metabolic process GO:0033240 0 0.029
oocyte construction GO:0007308 112 0.029
signal transduction in response to dna damage GO:0042770 3 0.029
hematopoietic or lymphoid organ development GO:0048534 57 0.028
endomembrane system organization GO:0010256 119 0.028
actin filament based process GO:0030029 220 0.028
negative regulation of molecular function GO:0044092 51 0.028
response to insulin GO:0032868 29 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.028
organonitrogen compound biosynthetic process GO:1901566 117 0.028
protein complex disassembly GO:0043241 36 0.028
regulation of oocyte development GO:0060281 27 0.027
cellular protein localization GO:0034613 160 0.027
regulation of organelle organization GO:0033043 196 0.027
negative regulation of apoptotic process GO:0043066 63 0.027
determination of bilateral symmetry GO:0009855 13 0.027
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.027
neuron remodeling GO:0016322 29 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
proteolysis GO:0006508 192 0.027
detection of stimulus GO:0051606 156 0.027
myotube differentiation GO:0014902 46 0.027
cellular response to dna damage stimulus GO:0006974 223 0.027
protein maturation GO:0051604 71 0.027
negative regulation of transferase activity GO:0051348 18 0.027
larval development GO:0002164 104 0.026
negative regulation of cell death GO:0060548 81 0.026
oocyte development GO:0048599 124 0.026
protein kinase b signaling GO:0043491 1 0.026
compound eye morphogenesis GO:0001745 249 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
phosphatidylinositol mediated signaling GO:0048015 4 0.026
somatic muscle development GO:0007525 66 0.026
cytosolic calcium ion transport GO:0060401 2 0.026
regulation of actin cytoskeleton organization GO:0032956 42 0.026
regulation of cellular catabolic process GO:0031329 157 0.025
epidermal growth factor receptor signaling pathway GO:0007173 58 0.025
actomyosin structure organization GO:0031032 56 0.025
negative regulation of erbb signaling pathway GO:1901185 29 0.025
hematopoietic progenitor cell differentiation GO:0002244 1 0.025
wnt signaling pathway GO:0016055 98 0.025
carbohydrate metabolic process GO:0005975 82 0.025
regulation of epithelial cell proliferation GO:0050678 4 0.025
negative chemotaxis GO:0050919 15 0.025
Zebrafish Fly
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
positive regulation of cell projection organization GO:0031346 29 0.025
nitrogen compound transport GO:0071705 85 0.025

Sema-1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.303
cancer DOID:162 0 0.187
disease of cellular proliferation DOID:14566 0 0.187
organ system cancer DOID:0050686 0 0.187
nervous system disease DOID:863 0 0.096