Drosophila melanogaster

0 known processes

alphaTry (Dmel_CG18444)

alphaTrypsin

(Aliases: DmAlphaTry,Try,Dmel\CG18444,CG18444,alpha,SP102)

alphaTry biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
innate immune response GO:0045087 144 0.626
phosphatidylethanolamine metabolic process GO:0046337 1 0.306
response to temperature stimulus GO:0009266 106 0.179
defense response to other organism GO:0098542 225 0.174
immune response GO:0006955 246 0.173
sterol homeostasis GO:0055092 4 0.131
homeostatic process GO:0042592 199 0.110
vesicle mediated transport GO:0016192 381 0.108
immune system process GO:0002376 347 0.105
response to cold GO:0009409 13 0.101
positive regulation of lipid storage GO:0010884 4 0.087
response to other organism GO:0051707 293 0.084
triglyceride biosynthetic process GO:0019432 2 0.082
salivary gland cell autophagic cell death GO:0035071 83 0.072
cholesterol transport GO:0030301 2 0.072
neutral lipid catabolic process GO:0046461 3 0.071
response to external biotic stimulus GO:0043207 293 0.069
regulation of immune response GO:0050776 118 0.069
response to abiotic stimulus GO:0009628 341 0.066
phosphatidic acid metabolic process GO:0046473 1 0.065
macromolecular complex assembly GO:0065003 256 0.064
regulation of immune system process GO:0002682 176 0.062
immune response activating signal transduction GO:0002757 2 0.058
positive regulation of multicellular organismal process GO:0051240 143 0.058
defense response GO:0006952 300 0.056
negative regulation of response to stimulus GO:0048585 258 0.052
endocytosis GO:0006897 310 0.052
neutral lipid biosynthetic process GO:0046460 2 0.051
regulation of transport GO:0051049 181 0.049
ethanolamine containing compound metabolic process GO:0042439 4 0.049
imaginal disc derived wing morphogenesis GO:0007476 337 0.048
positive regulation of signaling GO:0023056 243 0.046
gland development GO:0048732 191 0.045
regulation of defense response GO:0031347 102 0.045
lipid storage GO:0019915 38 0.044
defense response to gram negative bacterium GO:0050829 94 0.042
acylglycerol biosynthetic process GO:0046463 2 0.042
positive regulation of cell communication GO:0010647 250 0.041
negative regulation of immune system process GO:0002683 50 0.041
imaginal disc derived appendage development GO:0048737 399 0.041
phospholipid homeostasis GO:0055091 1 0.040
regulation of response to stress GO:0080134 200 0.039
immune effector process GO:0002252 98 0.039
cell proliferation GO:0008283 299 0.038
appendage morphogenesis GO:0035107 397 0.037
immune response regulating signaling pathway GO:0002764 2 0.037
fatty acid metabolic process GO:0006631 20 0.037
regulation of localization GO:0032879 275 0.037
negative regulation of cell communication GO:0010648 223 0.036
carboxylic acid metabolic process GO:0019752 92 0.035
positive regulation of sequestering of triglyceride GO:0010890 1 0.035
regulation of innate immune response GO:0045088 71 0.035
wing disc morphogenesis GO:0007472 344 0.035
small molecule metabolic process GO:0044281 305 0.034
cellular catabolic process GO:0044248 372 0.034
chemical homeostasis GO:0048878 92 0.034
sulfur compound biosynthetic process GO:0044272 16 0.034
positive regulation of signal transduction GO:0009967 223 0.034
regulation of cell cycle GO:0051726 291 0.033
intracellular signal transduction GO:0035556 300 0.032
response to biotic stimulus GO:0009607 294 0.031
regulation of multi organism process GO:0043900 131 0.031
response to fungus GO:0009620 50 0.030
acylglycerol catabolic process GO:0046464 3 0.030
innate immune response activating signal transduction GO:0002758 2 0.030
response to lipopolysaccharide GO:0032496 4 0.029
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.029
activation of innate immune response GO:0002218 4 0.029
response to virus GO:0009615 28 0.028
organic hydroxy compound metabolic process GO:1901615 83 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
negative regulation of signal transduction GO:0009968 206 0.027
maintenance of location GO:0051235 73 0.027
fatty acid biosynthetic process GO:0006633 6 0.027
positive regulation of response to stimulus GO:0048584 323 0.026
cell death GO:0008219 279 0.026
negative regulation of defense response GO:0031348 35 0.026
organophosphate catabolic process GO:0046434 112 0.026
protein complex biogenesis GO:0070271 201 0.025
catabolic process GO:0009056 409 0.025
cellular modified amino acid metabolic process GO:0006575 45 0.025
lipid biosynthetic process GO:0008610 46 0.025
cellular lipid metabolic process GO:0044255 83 0.025
small molecule biosynthetic process GO:0044283 37 0.024
negative regulation of signaling GO:0023057 219 0.024
anion homeostasis GO:0055081 3 0.024
regulation of intracellular signal transduction GO:1902531 236 0.023
ion homeostasis GO:0050801 55 0.023
carbohydrate derivative biosynthetic process GO:1901137 85 0.023
phagocytosis GO:0006909 215 0.022
pattern recognition receptor signaling pathway GO:0002221 2 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
cellular component assembly involved in morphogenesis GO:0010927 151 0.022
cellular amino acid metabolic process GO:0006520 61 0.021
single organism biosynthetic process GO:0044711 206 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
organic substance catabolic process GO:1901575 308 0.020
gland morphogenesis GO:0022612 145 0.020
cellular protein modification process GO:0006464 438 0.020
appendage development GO:0048736 401 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.020
body morphogenesis GO:0010171 2 0.020
regulation of lipid transport GO:0032368 3 0.019
response to organic substance GO:0010033 284 0.019
response to copper ion GO:0046688 4 0.018
developmental programmed cell death GO:0010623 138 0.018
cold acclimation GO:0009631 8 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
regulation of response to biotic stimulus GO:0002831 63 0.018
phosphatidylcholine metabolic process GO:0046470 3 0.018
heparan sulfate proteoglycan biosynthetic process GO:0015012 10 0.017
triglyceride catabolic process GO:0019433 3 0.017
organophosphate metabolic process GO:0019637 195 0.017
death GO:0016265 284 0.017
oxoacid metabolic process GO:0043436 103 0.017
regulation of lipid storage GO:0010883 22 0.017
lipid metabolic process GO:0006629 121 0.017
proteolysis GO:0006508 192 0.017
protein modification process GO:0036211 438 0.017
mitotic nuclear division GO:0007067 213 0.017
autophagic cell death GO:0048102 83 0.017
response to peptide hormone GO:0043434 29 0.017
negative regulation of intracellular signal transduction GO:1902532 57 0.017
circadian rhythm GO:0007623 105 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.016
exocrine system development GO:0035272 162 0.016
response to metal ion GO:0010038 23 0.016
amine metabolic process GO:0009308 12 0.016
alcohol metabolic process GO:0006066 25 0.016
ion transport GO:0006811 145 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
positive regulation of transport GO:0051050 92 0.015
developmental maturation GO:0021700 172 0.015
regulation of sterol transport GO:0032371 1 0.015
organic substance transport GO:0071702 257 0.015
defense response to bacterium GO:0042742 178 0.015
organic acid metabolic process GO:0006082 103 0.015
response to endogenous stimulus GO:0009719 119 0.014
developmental growth GO:0048589 280 0.014
regulation of catabolic process GO:0009894 170 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
regulation of defense response to virus GO:0050688 14 0.014
glycerolipid metabolic process GO:0046486 34 0.014
tissue death GO:0016271 102 0.014
cellular amine metabolic process GO:0044106 12 0.013
phosphorylation GO:0016310 294 0.013
proteoglycan metabolic process GO:0006029 10 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
mating GO:0007618 120 0.012
regulation of cholesterol transport GO:0032374 1 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
glycoprotein biosynthetic process GO:0009101 41 0.012
regulation of response to external stimulus GO:0032101 115 0.012
positive regulation of immune response GO:0050778 63 0.012
cellular biogenic amine metabolic process GO:0006576 9 0.012
protein complex assembly GO:0006461 200 0.012
lipid localization GO:0010876 54 0.012
growth GO:0040007 359 0.012
salivary gland histolysis GO:0035070 88 0.012
regulation of cell death GO:0010941 173 0.012
response to bacterium GO:0009617 198 0.012
salivary gland development GO:0007431 162 0.012
macromolecule catabolic process GO:0009057 161 0.012
regulation of cell development GO:0060284 215 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
actin cytoskeleton organization GO:0030036 206 0.011
response to calcium ion GO:0051592 1 0.011
response to oxygen levels GO:0070482 59 0.011
kidney development GO:0001822 3 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
cellular macromolecule localization GO:0070727 220 0.011
salivary gland morphogenesis GO:0007435 145 0.011
triglyceride metabolic process GO:0006641 12 0.011
response to organic cyclic compound GO:0014070 89 0.011
camera type eye development GO:0043010 4 0.011
regulation of molecular function GO:0065009 217 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
histolysis GO:0007559 102 0.011
carboxylic acid biosynthetic process GO:0046394 15 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
cell division GO:0051301 248 0.011
notch signaling pathway GO:0007219 120 0.011
rna processing GO:0006396 147 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
positive regulation of defense response GO:0031349 59 0.011
actin filament based process GO:0030029 220 0.010
alditol phosphate metabolic process GO:0052646 2 0.010
autophagy GO:0006914 108 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
negative regulation of rna biosynthetic process GO:1902679 240 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
synapse assembly GO:0007416 143 0.010
rho protein signal transduction GO:0007266 14 0.010

alphaTry disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.212
inherited metabolic disorder DOID:655 0 0.097
familial combined hyperlipidemia DOID:13809 0 0.097
familial hyperlipidemia DOID:1168 0 0.097
lipid metabolism disorder DOID:3146 0 0.097
disease of anatomical entity DOID:7 0 0.086
hair disease DOID:421 0 0.055
hypotrichosis DOID:4535 0 0.055
integumentary system disease DOID:16 0 0.055
acquired metabolic disease DOID:0060158 0 0.053
carbohydrate metabolism disease DOID:0050013 0 0.034
diabetes mellitus DOID:9351 0 0.034
glucose metabolism disease DOID:4194 0 0.034
type 2 diabetes mellitus DOID:9352 0 0.030
familial lipoprotein lipase deficiency DOID:14118 0 0.024
familial hypertriglyceridemia DOID:0050527 0 0.015