Drosophila melanogaster

247 known processes

Tak1 (Dmel_CG18492)

TGF-beta activated kinase 1

(Aliases: dTAK-1,TAK1,DmTak1,DTAK1,CG18492,D10,tak,D-TAK,dTak1,dTak,Dmel\CG18492,TAK-1,D-tak,DTak1,Tak 1,DTak,dTAK1,tak1,CG1388,dTAK,TAK,Tak)

Tak1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 294 0.945
imaginal disc derived appendage development GO:0048737 399 0.925
regulation of defense response to virus by host GO:0050691 10 0.899
positive regulation of nucleic acid templated transcription GO:1903508 266 0.897
positive regulation of multicellular organismal process GO:0051240 143 0.896
Human
response to virus GO:0009615 28 0.889
intracellular signal transduction GO:0035556 300 0.856
programmed cell death GO:0012501 257 0.845
developmental programmed cell death GO:0010623 138 0.827
positive regulation of gene expression GO:0010628 290 0.806
defense response to other organism GO:0098542 225 0.774
regulation of multicellular organismal development GO:2000026 414 0.750
regulation of defense response to virus GO:0050688 14 0.750
post embryonic appendage morphogenesis GO:0035120 385 0.739
female meiotic division GO:0007143 70 0.737
imaginal disc derived wing morphogenesis GO:0007476 337 0.735
asymmetric protein localization GO:0008105 33 0.732
Worm
morphogenesis of an epithelium GO:0002009 276 0.724
transcription from rna polymerase ii promoter GO:0006366 368 0.722
apoptotic process GO:0006915 159 0.716
regulation of anatomical structure morphogenesis GO:0022603 242 0.715
positive regulation of macromolecule metabolic process GO:0010604 405 0.704
regulation of proteolysis GO:0030162 87 0.698
positive regulation of rna biosynthetic process GO:1902680 266 0.693
appendage morphogenesis GO:0035107 397 0.683
regulation of immune effector process GO:0002697 52 0.667
positive regulation of defense response to virus by host GO:0002230 10 0.653
immune response GO:0006955 246 0.643
macromolecule catabolic process GO:0009057 161 0.633
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.629
proteolysis GO:0006508 192 0.624
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.612
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.604
defense response to gram negative bacterium GO:0050829 94 0.581
phosphorylation GO:0016310 294 0.580
positive regulation of response to stimulus GO:0048584 323 0.562
embryonic morphogenesis GO:0048598 206 0.547
regulation of multicellular organism growth GO:0040014 40 0.544
response to other organism GO:0051707 293 0.543
immune system process GO:0002376 347 0.539
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.533
regulation of immune system process GO:0002682 176 0.524
regulation of cysteine type endopeptidase activity GO:2000116 27 0.523
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.502
positive regulation of cellular biosynthetic process GO:0031328 316 0.502
cell junction organization GO:0034330 57 0.501
response to external biotic stimulus GO:0043207 293 0.498
regulation of response to external stimulus GO:0032101 115 0.495
positive regulation of biosynthetic process GO:0009891 316 0.482
positive regulation of rna metabolic process GO:0051254 271 0.478
wnt signaling pathway GO:0016055 98 0.478
protein modification process GO:0036211 438 0.475
humoral immune response GO:0006959 117 0.473
activation of cysteine type endopeptidase activity GO:0097202 17 0.468
positive regulation of signal transduction GO:0009967 223 0.463
regulation of immune response GO:0050776 118 0.454
cell death GO:0008219 279 0.453
regulation of multi organism process GO:0043900 131 0.447
regulation of developmental growth GO:0048638 174 0.443
protein localization GO:0008104 284 0.430
Worm
aging GO:0007568 143 0.423
adherens junction organization GO:0034332 27 0.420
cell cell junction organization GO:0045216 55 0.411
protein catabolic process GO:0030163 101 0.409
protein maturation GO:0051604 71 0.403
positive regulation of proteolysis GO:0045862 52 0.401
catabolic process GO:0009056 409 0.400
cellular protein modification process GO:0006464 438 0.399
death GO:0016265 284 0.397
modification dependent protein catabolic process GO:0019941 78 0.395
negative regulation of cellular protein metabolic process GO:0032269 85 0.395
ion transport GO:0006811 145 0.394
response to organonitrogen compound GO:0010243 75 0.389
tube morphogenesis GO:0035239 191 0.382
Mouse Worm
negative regulation of cellular metabolic process GO:0031324 382 0.382
Mouse
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.381
imaginal disc derived appendage morphogenesis GO:0035114 395 0.373
peptide metabolic process GO:0006518 80 0.373
positive regulation of phosphate metabolic process GO:0045937 139 0.368
lateral inhibition GO:0046331 206 0.364
response to bacterium GO:0009617 198 0.357
regulation of hydrolase activity GO:0051336 97 0.356
positive regulation of transcription dna templated GO:0045893 266 0.350
growth GO:0040007 359 0.339
regulation of growth GO:0040008 233 0.336
gastrulation with mouth forming first GO:0001703 36 0.336
morphogenesis of embryonic epithelium GO:0016331 94 0.336
regulation of programmed cell death GO:0043067 152 0.332
Mouse
intracellular transport GO:0046907 228 0.331
cellular protein catabolic process GO:0044257 83 0.325
cell cell signaling involved in cell fate commitment GO:0045168 210 0.321
gland development GO:0048732 191 0.319
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.308
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.308
organic substance catabolic process GO:1901575 308 0.303
regulation of antimicrobial humoral response GO:0002759 50 0.303
modification dependent macromolecule catabolic process GO:0043632 79 0.303
deactivation of rhodopsin mediated signaling GO:0016059 17 0.302
positive regulation of immune response GO:0050778 63 0.292
regulation of phosphate metabolic process GO:0019220 210 0.289
cilium organization GO:0044782 41 0.286
multicellular organismal aging GO:0010259 140 0.285
regulation of wnt signaling pathway GO:0030111 68 0.281
digestive system development GO:0055123 149 0.279
Worm
regulation of anatomical structure size GO:0090066 163 0.277
antimicrobial humoral response GO:0019730 99 0.273
regulation of molecular function GO:0065009 217 0.272
transmembrane transport GO:0055085 139 0.271
defense response GO:0006952 300 0.266
protein processing GO:0016485 68 0.262
cellular response to oxygen containing compound GO:1901701 79 0.258
negative regulation of developmental process GO:0051093 201 0.253
positive regulation of catalytic activity GO:0043085 118 0.252
ubiquitin dependent protein catabolic process GO:0006511 78 0.246
body morphogenesis GO:0010171 2 0.240
larval development GO:0002164 104 0.240
carbohydrate derivative catabolic process GO:1901136 118 0.238
regulation of organ morphogenesis GO:2000027 78 0.236
epithelial cell development GO:0002064 274 0.236
antibacterial humoral response GO:0019731 44 0.236
appendage development GO:0048736 401 0.232
negative regulation of cell death GO:0060548 81 0.230
Mouse
dorsal closure GO:0007391 79 0.230
positive regulation of cell communication GO:0010647 250 0.229
negative regulation of programmed cell death GO:0043069 72 0.226
Mouse
regulation of cell differentiation GO:0045595 302 0.226
embryo development ending in birth or egg hatching GO:0009792 152 0.220
multicellular organism growth GO:0035264 46 0.217
regulation of phosphorylation GO:0042325 147 0.216
endocytosis GO:0006897 310 0.214
regulation of cellular protein metabolic process GO:0032268 243 0.212
wing disc morphogenesis GO:0007472 344 0.212
cellular catabolic process GO:0044248 372 0.209
compound eye retinal cell programmed cell death GO:0046667 23 0.205
immune effector process GO:0002252 98 0.204
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.203
protein phosphorylation GO:0006468 169 0.194
regionalization GO:0003002 416 0.193
regulation of protein metabolic process GO:0051246 256 0.191
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.189
positive regulation of protein transport GO:0051222 37 0.188
epithelial cell differentiation GO:0030855 322 0.187
cation transport GO:0006812 110 0.185
purine nucleotide metabolic process GO:0006163 146 0.185
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.180
epithelial cell migration GO:0010631 148 0.175
regulation of catalytic activity GO:0050790 185 0.174
positive regulation of growth GO:0045927 75 0.172
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.171
Human Mouse Rat
head involution GO:0008258 35 0.169
cell cycle phase transition GO:0044770 140 0.167
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.166
negative regulation of cell differentiation GO:0045596 143 0.165
regulation of response to biotic stimulus GO:0002831 63 0.161
regulation of peptidase activity GO:0052547 39 0.161
regulation of kinase activity GO:0043549 53 0.161
photoreceptor cell development GO:0042461 96 0.161
cell division GO:0051301 248 0.158
Worm
positive regulation of intracellular signal transduction GO:1902533 116 0.158
negative regulation of cellular biosynthetic process GO:0031327 277 0.158
positive regulation of multicellular organism growth GO:0040018 21 0.157
lipid metabolic process GO:0006629 121 0.157
chaeta development GO:0022416 97 0.157
ovarian follicle cell development GO:0030707 248 0.156
defense response to bacterium GO:0042742 178 0.155
organophosphate metabolic process GO:0019637 195 0.151
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.150
response to lipopolysaccharide GO:0032496 4 0.145
negative regulation of catalytic activity GO:0043086 42 0.143
cellular response to lipopolysaccharide GO:0071222 3 0.141
tube development GO:0035295 244 0.137
Mouse Worm
immune response activating signal transduction GO:0002757 2 0.136
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.130
defense response to virus GO:0051607 23 0.130
regulation of intracellular signal transduction GO:1902531 236 0.129
cell proliferation GO:0008283 299 0.128
cilium morphogenesis GO:0060271 39 0.127
purine nucleoside catabolic process GO:0006152 112 0.127
nucleotide metabolic process GO:0009117 161 0.125
establishment of localization in cell GO:0051649 402 0.124
purine ribonucleotide metabolic process GO:0009150 145 0.124
sensory organ morphogenesis GO:0090596 260 0.123
regulation of gtpase activity GO:0043087 44 0.119
regulation of canonical wnt signaling pathway GO:0060828 15 0.119
positive regulation of phosphorus metabolic process GO:0010562 139 0.118
developmental growth GO:0048589 280 0.116
retinal cell programmed cell death GO:0046666 25 0.115
purine ribonucleoside catabolic process GO:0046130 112 0.115
ion transmembrane transport GO:0034220 122 0.115
positive regulation of protein localization to nucleus GO:1900182 21 0.114
axon ensheathment GO:0008366 10 0.114
positive regulation of developmental process GO:0051094 143 0.113
cell recognition GO:0008037 102 0.113
cytoplasmic transport GO:0016482 130 0.112
nucleotide catabolic process GO:0009166 109 0.112
mitotic cell cycle phase transition GO:0044772 138 0.111
antimicrobial peptide production GO:0002775 46 0.111
regulation of catabolic process GO:0009894 170 0.109
organonitrogen compound biosynthetic process GO:1901566 117 0.109
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.109
cell motility GO:0048870 251 0.108
establishment of tissue polarity GO:0007164 87 0.107
regulation of cellular localization GO:0060341 136 0.107
cell adhesion GO:0007155 136 0.107
oocyte differentiation GO:0009994 145 0.105
vesicle mediated transport GO:0016192 381 0.103
negative regulation of compound eye retinal cell programmed cell death GO:0046673 7 0.102
regulation of cell death GO:0010941 173 0.100
Mouse
establishment of organelle localization GO:0051656 122 0.099
ribose phosphate metabolic process GO:0019693 145 0.099
regulation of defense response GO:0031347 102 0.099
regulation of ion transport GO:0043269 39 0.098
organic substance transport GO:0071702 257 0.097
regulation of vesicle mediated transport GO:0060627 59 0.095
regulation of endocytosis GO:0030100 37 0.094
response to nitrogen compound GO:1901698 90 0.092
negative regulation of multicellular organismal process GO:0051241 142 0.092
positive regulation of apoptotic process GO:0043065 47 0.092
regulation of endopeptidase activity GO:0052548 36 0.090
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.090
negative regulation of phosphorylation GO:0042326 35 0.090
phagocytosis GO:0006909 215 0.089
actin filament based movement GO:0030048 26 0.089
single organism nuclear import GO:1902593 51 0.088
negative regulation of signaling GO:0023057 219 0.087
Mouse
cognition GO:0050890 141 0.087
mitotic cytokinesis GO:0000281 50 0.086
developmental pigmentation GO:0048066 68 0.086
nucleobase containing small molecule metabolic process GO:0055086 174 0.085
positive regulation of histone deacetylation GO:0031065 2 0.084
ribonucleoside catabolic process GO:0042454 112 0.083
organelle fission GO:0048285 340 0.083
negative regulation of molecular function GO:0044092 51 0.082
positive regulation of cell death GO:0010942 69 0.082
regulation of cell development GO:0060284 215 0.082
response to organic substance GO:0010033 284 0.081
ensheathment of neurons GO:0007272 10 0.081
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.079
Worm
apical constriction GO:0003383 18 0.078
apical constriction involved in gastrulation GO:0003384 7 0.078
regulation of cell shape GO:0008360 113 0.077
positive regulation of developmental growth GO:0048639 62 0.077
embryonic development via the syncytial blastoderm GO:0001700 148 0.077
regulation of cellular component biogenesis GO:0044087 201 0.077
Mouse
nucleoside triphosphate catabolic process GO:0009143 108 0.076
asymmetric stem cell division GO:0098722 49 0.076
innate immune response GO:0045087 144 0.076
regulation of stress activated mapk cascade GO:0032872 41 0.076
digestive tract morphogenesis GO:0048546 127 0.076
Worm
olfactory learning GO:0008355 56 0.075
regulation of epidermal cell differentiation GO:0045604 3 0.075
cell projection assembly GO:0030031 94 0.074
transmission of nerve impulse GO:0019226 12 0.073
gtp catabolic process GO:0006184 72 0.073
mapk cascade GO:0000165 107 0.072
i kappab kinase nf kappab signaling GO:0007249 6 0.072
localization of cell GO:0051674 257 0.072
negative regulation of cell proliferation GO:0008285 69 0.072
respiratory system development GO:0060541 213 0.072
gastrulation involving germ band extension GO:0010004 36 0.071
regulation of nervous system development GO:0051960 248 0.071
response to osmotic stress GO:0006970 14 0.071
synaptic growth at neuromuscular junction GO:0051124 119 0.069
purine containing compound metabolic process GO:0072521 155 0.069
cellular protein localization GO:0034613 160 0.069
positive regulation of transport GO:0051050 92 0.069
negative regulation of mitotic cell cycle GO:0045930 109 0.068
immune response regulating signaling pathway GO:0002764 2 0.068
protein transport GO:0015031 155 0.068
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.067
small molecule metabolic process GO:0044281 305 0.067
protein localization to nucleus GO:0034504 55 0.066
proteasomal protein catabolic process GO:0010498 59 0.066
negative regulation of cell communication GO:0010648 223 0.065
Mouse
positive regulation of immune effector process GO:0002699 28 0.064
purine nucleoside triphosphate metabolic process GO:0009144 119 0.064
molting cycle GO:0042303 56 0.063
peripheral nervous system development GO:0007422 52 0.063
protein import into nucleus GO:0006606 51 0.062
regulation of histone deacetylation GO:0031063 2 0.062
negative regulation of proteolysis GO:0045861 31 0.062
actin mediated cell contraction GO:0070252 21 0.060
cellular macromolecule localization GO:0070727 220 0.060
negative regulation of phosphorus metabolic process GO:0010563 45 0.060
purine containing compound catabolic process GO:0072523 112 0.060
actin filament polymerization GO:0030041 27 0.059
epidermal cell differentiation GO:0009913 51 0.059
canonical wnt signaling pathway GO:0060070 21 0.059
regulation of embryonic cell shape GO:0016476 30 0.059
meiotic nuclear division GO:0007126 151 0.058
regulation of phosphorus metabolic process GO:0051174 210 0.058
protein localization to organelle GO:0033365 82 0.057
regulation of membrane potential GO:0042391 35 0.057
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.056
negative regulation of wnt signaling pathway GO:0030178 28 0.056
regulation of synapse organization GO:0050807 110 0.056
cellular macromolecule catabolic process GO:0044265 136 0.055
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.055
regulation of jnk cascade GO:0046328 40 0.055
negative regulation of rna metabolic process GO:0051253 251 0.055
regulation of transport GO:0051049 181 0.055
regulation of defense response to bacterium GO:1900424 30 0.054
regulation of humoral immune response GO:0002920 51 0.054
regulation of purine nucleotide catabolic process GO:0033121 48 0.054
regulation of localization GO:0032879 275 0.054
hair cell differentiation GO:0035315 47 0.054
cytoplasmic microtubule organization GO:0031122 22 0.054
apoptotic cell clearance GO:0043277 14 0.053
dephosphorylation GO:0016311 51 0.053
cellular response to biotic stimulus GO:0071216 4 0.052
regulation of imaginal disc growth GO:0045570 26 0.052
organonitrogen compound catabolic process GO:1901565 128 0.052
establishment of protein localization GO:0045184 163 0.052
neurological system process GO:0050877 358 0.052
exocytosis GO:0006887 28 0.051
regulation of cellular catabolic process GO:0031329 157 0.051
positive regulation of peptidase activity GO:0010952 29 0.051
organophosphate catabolic process GO:0046434 112 0.051
regulation of apoptotic process GO:0042981 130 0.050
Mouse
head development GO:0060322 135 0.049
regulation of retinal cell programmed cell death GO:0046668 18 0.049
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.049
protein modification by small protein conjugation or removal GO:0070647 106 0.048
oocyte axis specification GO:0007309 108 0.048
negative regulation of protein processing GO:0010955 31 0.048
regulation of nucleotide metabolic process GO:0006140 62 0.048
innate immune response activating signal transduction GO:0002758 2 0.048
actin filament based process GO:0030029 220 0.048
negative regulation of cell development GO:0010721 62 0.048
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.048
Human Mouse Rat
negative regulation of developmental growth GO:0048640 64 0.048
ribonucleoside triphosphate catabolic process GO:0009203 108 0.047
g protein coupled receptor signaling pathway GO:0007186 136 0.047
regulation of antibacterial peptide production GO:0002786 22 0.046
compound eye morphogenesis GO:0001745 249 0.046
positive regulation of multi organism process GO:0043902 40 0.046
regulation of response to stress GO:0080134 200 0.046
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.046
regulation of mitotic cell cycle phase transition GO:1901990 130 0.046
single organism biosynthetic process GO:0044711 206 0.046
single organism catabolic process GO:0044712 228 0.045
nucleocytoplasmic transport GO:0006913 72 0.045
metal ion transport GO:0030001 74 0.045
oocyte development GO:0048599 124 0.045
cellular response to cadmium ion GO:0071276 6 0.045
regulation of protein import into nucleus GO:0042306 28 0.044
protein ubiquitination GO:0016567 70 0.044
morphogenesis of a polarized epithelium GO:0001738 93 0.043
ribonucleoside metabolic process GO:0009119 127 0.043
dorsal closure spreading of leading edge cells GO:0007395 4 0.043
biological adhesion GO:0022610 138 0.043
positive regulation of hydrolase activity GO:0051345 78 0.043
positive regulation of catabolic process GO:0009896 105 0.042
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.042
negative regulation of cell cycle process GO:0010948 109 0.041
ribonucleotide metabolic process GO:0009259 145 0.041
gastrulation GO:0007369 70 0.041
Worm
development of primary sexual characteristics GO:0045137 50 0.041
regulation of protein kinase activity GO:0045859 51 0.041
regulation of cellular amide metabolic process GO:0034248 39 0.041
cell activation GO:0001775 9 0.041
heterocycle catabolic process GO:0046700 166 0.040
regulation of nucleoside metabolic process GO:0009118 50 0.040
jnk cascade GO:0007254 50 0.040
guanosine containing compound catabolic process GO:1901069 74 0.039
neuroblast proliferation GO:0007405 74 0.039
germ line stem cell maintenance GO:0030718 50 0.039
establishment of planar polarity GO:0001736 87 0.039
developmental maturation GO:0021700 172 0.039
regulation of mapk cascade GO:0043408 92 0.039
negative regulation of protein metabolic process GO:0051248 85 0.039
epithelial cell morphogenesis GO:0003382 25 0.038
positive regulation of immune system process GO:0002684 68 0.038
gliogenesis GO:0042063 80 0.038
negative regulation of cell cycle phase transition GO:1901988 103 0.038
regulation of intracellular protein transport GO:0033157 46 0.038
nucleobase containing compound catabolic process GO:0034655 165 0.038
regulation of locomotion GO:0040012 42 0.038
negative regulation of nucleic acid templated transcription GO:1903507 240 0.037
negative regulation of transcription dna templated GO:0045892 237 0.037
positive regulation of cell migration GO:0030335 2 0.037
tissue homeostasis GO:0001894 36 0.037
antibacterial peptide biosynthetic process GO:0002780 22 0.037
cellular component assembly involved in morphogenesis GO:0010927 151 0.037
neuromuscular junction development GO:0007528 149 0.037
regulation of production of molecular mediator of immune response GO:0002700 44 0.036
compound eye development GO:0048749 307 0.036
response to endoplasmic reticulum stress GO:0034976 28 0.036
telencephalon development GO:0021537 2 0.036
positive regulation of cell size GO:0045793 21 0.036
negative regulation of retinal cell programmed cell death GO:0046671 7 0.036
single organismal cell cell adhesion GO:0016337 45 0.036
regulation of system process GO:0044057 36 0.036
single organism cell adhesion GO:0098602 47 0.035
regulation of innate immune response GO:0045088 71 0.035
molting cycle chitin based cuticle GO:0007591 56 0.035
cytoskeleton dependent cytokinesis GO:0061640 81 0.035
mitotic dna damage checkpoint GO:0044773 74 0.035
regulation of cell cycle GO:0051726 291 0.035
protein autophosphorylation GO:0046777 15 0.035
Worm
extrinsic apoptotic signaling pathway GO:0097191 1 0.034
response to metal ion GO:0010038 23 0.034
meiotic cell cycle GO:0051321 171 0.034
regulation of protein processing GO:0070613 32 0.034
epithelium migration GO:0090132 148 0.034
response to oxygen containing compound GO:1901700 200 0.034
response to copper ion GO:0046688 4 0.034
skin development GO:0043588 65 0.034
axon guidance GO:0007411 233 0.034
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.034
regulation of protein phosphorylation GO:0001932 64 0.033
cellular response to chemical stimulus GO:0070887 199 0.033
activation of jun kinase activity GO:0007257 3 0.033
anion transport GO:0006820 41 0.033
ribonucleotide catabolic process GO:0009261 109 0.033
positive regulation of jun kinase activity GO:0043507 4 0.033
positive regulation of nucleoside metabolic process GO:0045979 47 0.033
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.033
columnar cuboidal epithelial cell development GO:0002066 249 0.032
non sensory hair organization GO:0035316 47 0.032
protein targeting GO:0006605 64 0.032
regulation of cell adhesion GO:0030155 27 0.032
protein targeting to nucleus GO:0044744 51 0.032
positive regulation of protein import into nucleus GO:0042307 21 0.032
positive regulation of protein metabolic process GO:0051247 128 0.032
regulation of nucleotide catabolic process GO:0030811 48 0.032
protein complex assembly GO:0006461 200 0.032
Mouse
regulation of cellular component size GO:0032535 98 0.031
regulation of purine nucleotide metabolic process GO:1900542 62 0.031
protein complex biogenesis GO:0070271 201 0.031
Mouse
synaptic transmission GO:0007268 288 0.031
neuronal action potential GO:0019228 10 0.031
regulation of protein transport GO:0051223 57 0.031
positive regulation of wnt signaling pathway GO:0030177 25 0.031
purine nucleoside metabolic process GO:0042278 127 0.031
positive regulation of response to biotic stimulus GO:0002833 31 0.030
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.030
regulation of epithelial cell proliferation GO:0050678 4 0.030
positive regulation of protein complex assembly GO:0031334 22 0.030
negative regulation of growth GO:0045926 84 0.030
collateral sprouting GO:0048668 3 0.030
regulation of cell cycle process GO:0010564 181 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.030
regulation of cytoskeleton organization GO:0051493 89 0.030
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.029
ectodermal placode development GO:0071696 4 0.029
non canonical wnt signaling pathway GO:0035567 8 0.029
nephron tubule development GO:0072080 3 0.029
cellular macromolecular complex assembly GO:0034622 153 0.029
cellular nitrogen compound catabolic process GO:0044270 165 0.029
regulation of antifungal peptide production GO:0002788 6 0.029
regulation of nucleocytoplasmic transport GO:0046822 35 0.029
skeletal muscle fiber development GO:0048741 3 0.029
forebrain development GO:0030900 2 0.029
cellular response to peptide hormone stimulus GO:0071375 28 0.029
axis elongation GO:0003401 3 0.028
aromatic compound catabolic process GO:0019439 166 0.028
mitotic spindle organization GO:0007052 220 0.028
learning or memory GO:0007611 141 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
positive regulation of cellular component organization GO:0051130 156 0.028
nucleoside metabolic process GO:0009116 127 0.028
cell junction assembly GO:0034329 42 0.028
olfactory behavior GO:0042048 97 0.028
cilium assembly GO:0042384 38 0.028
nephron development GO:0072006 3 0.028
negative regulation of signal transduction GO:0009968 206 0.028
Mouse
regulation of dna metabolic process GO:0051052 34 0.027
extracellular matrix organization GO:0030198 32 0.027
guanosine containing compound metabolic process GO:1901068 74 0.027
jak stat cascade GO:0007259 49 0.027
pattern recognition receptor signaling pathway GO:0002221 2 0.027
regulation of cell substrate adhesion GO:0010810 2 0.027
positive regulation of antimicrobial peptide production GO:0002225 28 0.027
eye photoreceptor cell differentiation GO:0001754 145 0.027
regulation of actin polymerization or depolymerization GO:0008064 27 0.026
positive regulation of mapk cascade GO:0043410 63 0.026
chromatin organization GO:0006325 207 0.026
Human
photoreceptor cell differentiation GO:0046530 170 0.026
myotube differentiation GO:0014902 46 0.026
establishment of protein localization to organelle GO:0072594 62 0.026
glycosyl compound metabolic process GO:1901657 127 0.026
photoreceptor cell maintenance GO:0045494 11 0.026
endomembrane system organization GO:0010256 119 0.026
regulation of protein localization to nucleus GO:1900180 29 0.026
nuclear division GO:0000280 332 0.025
intracellular protein transport GO:0006886 104 0.025
dna metabolic process GO:0006259 227 0.025
positive regulation of cell cycle g2 m phase transition GO:1902751 2 0.025
negative regulation of gene expression GO:0010629 387 0.025
activation of innate immune response GO:0002218 4 0.025
glial cell differentiation GO:0010001 35 0.025
regulation of cell projection organization GO:0031344 92 0.025
cellular response to nitrogen compound GO:1901699 51 0.025

Tak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
motor neuron disease DOID:231 0 0.059
central nervous system disease DOID:331 0 0.059
disease of anatomical entity DOID:7 0 0.059
neurodegenerative disease DOID:1289 0 0.059
nervous system disease DOID:863 0 0.059