Drosophila melanogaster

187 known processes

spen (Dmel_CG18497)

split ends

(Aliases: l(2)k06805,rno,EY2-7,BcDNA:GM01870,yip1,CG18497,136/24,l(2)k07612,E(Sev-CycE)2A,E(E2F)2A,poc,l(2)03350,l(2)k08102,spe,EK2-9,En(yan[ACT])2-7,E(Raf)2A,Dmel\CG18497,Splitends)

spen biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 1.000
eye morphogenesis GO:0048592 260 0.985
regionalization GO:0003002 416 0.985
negative regulation of nucleic acid templated transcription GO:1903507 240 0.982
Human Mouse
sensory organ morphogenesis GO:0090596 260 0.981
compound eye development GO:0048749 307 0.970
axis specification GO:0009798 167 0.967
hindbrain development GO:0030902 2 0.939
axon guidance GO:0007411 233 0.921
negative regulation of biosynthetic process GO:0009890 277 0.918
Human Mouse
negative regulation of rna metabolic process GO:0051253 251 0.912
Human Mouse
axon development GO:0061564 297 0.911
eye photoreceptor cell differentiation GO:0001754 145 0.901
compound eye morphogenesis GO:0001745 249 0.896
dorsal ventral pattern formation GO:0009953 133 0.892
transcription from rna polymerase ii promoter GO:0006366 368 0.892
Human
regulation of multicellular organismal development GO:2000026 414 0.886
Human
cognition GO:0050890 141 0.873
axonogenesis GO:0007409 290 0.850
chemotaxis GO:0006935 249 0.845
oocyte microtubule cytoskeleton organization GO:0016325 35 0.839
eye photoreceptor cell development GO:0042462 81 0.831
regulation of embryonic development GO:0045995 68 0.815
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.803
Human
epithelial cell differentiation GO:0030855 322 0.801
anterior posterior pattern specification GO:0009952 136 0.798
positive regulation of transcription dna templated GO:0045893 266 0.796
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.793
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.788
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.783
Human Mouse
digestive tract morphogenesis GO:0048546 127 0.773
negative regulation of transcription dna templated GO:0045892 237 0.766
Human Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.766
positive regulation of nucleic acid templated transcription GO:1903508 266 0.759
Mouse
regulation of cell development GO:0060284 215 0.757
Human
r7 cell differentiation GO:0045466 43 0.751
positive regulation of gene expression GO:0010628 290 0.741
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.731
Human Mouse
oocyte axis specification GO:0007309 108 0.730
gastrulation GO:0007369 70 0.726
compound eye photoreceptor development GO:0042051 78 0.725
cell fate determination GO:0001709 91 0.694
rhythmic process GO:0048511 106 0.676
locomotory behavior GO:0007626 176 0.676
learning or memory GO:0007611 141 0.674
negative regulation of multicellular organismal process GO:0051241 142 0.671
forebrain development GO:0030900 2 0.671
response to biotic stimulus GO:0009607 294 0.668
segmentation GO:0035282 207 0.666
photoreceptor cell differentiation GO:0046530 170 0.653
regulation of anatomical structure morphogenesis GO:0022603 242 0.626
regulation of nervous system development GO:0051960 248 0.626
Human
enzyme linked receptor protein signaling pathway GO:0007167 179 0.622
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.617
Mouse
motor neuron axon guidance GO:0008045 58 0.609
oocyte development GO:0048599 124 0.607
positive regulation of biosynthetic process GO:0009891 316 0.588
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.586
tripartite regional subdivision GO:0007351 103 0.585
negative regulation of cell differentiation GO:0045596 143 0.581
photoreceptor cell development GO:0042461 96 0.579
epithelial cell development GO:0002064 274 0.578
muscle structure development GO:0061061 224 0.571
anterior posterior axis specification embryo GO:0008595 103 0.563
imaginal disc pattern formation GO:0007447 91 0.556
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.525
regulation of cell size GO:0008361 63 0.525
regulation of multi organism process GO:0043900 131 0.518
homeostatic process GO:0042592 199 0.516
lateral inhibition GO:0046331 206 0.514
positive regulation of rna metabolic process GO:0051254 271 0.513
Mouse
embryonic morphogenesis GO:0048598 206 0.512
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.498
developmental maturation GO:0021700 172 0.462
head development GO:0060322 135 0.454
neuron projection guidance GO:0097485 241 0.454
detection of stimulus GO:0051606 156 0.453
negative regulation of response to stimulus GO:0048585 258 0.447
negative regulation of gene expression GO:0010629 387 0.443
Human Mouse
anterior posterior axis specification GO:0009948 109 0.435
establishment of localization in cell GO:0051649 402 0.425
cell fate specification GO:0001708 71 0.423
regulation of localization GO:0032879 275 0.422
synapse assembly GO:0007416 143 0.418
regulation of phosphate metabolic process GO:0019220 210 0.412
taxis GO:0042330 304 0.410
regulation of neurogenesis GO:0050767 158 0.405
Human
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.405
Human Mouse
cell proliferation GO:0008283 299 0.394
retinal ganglion cell axon guidance GO:0031290 12 0.393
oocyte differentiation GO:0009994 145 0.387
maternal determination of anterior posterior axis embryo GO:0008358 74 0.387
developmental growth GO:0048589 280 0.386
negative regulation of signaling GO:0023057 219 0.384
cell maturation GO:0048469 144 0.382
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.380
regulation of programmed cell death GO:0043067 152 0.368
regulation of cellular localization GO:0060341 136 0.364
synaptic growth at neuromuscular junction GO:0051124 119 0.357
stem cell differentiation GO:0048863 117 0.337
regulation of growth GO:0040008 233 0.333
cellular catabolic process GO:0044248 372 0.331
protein modification process GO:0036211 438 0.331
regulation of photoreceptor cell differentiation GO:0046532 34 0.331
regulation of dendrite morphogenesis GO:0048814 28 0.330
regulation of r7 cell differentiation GO:0045676 15 0.329
oocyte construction GO:0007308 112 0.328
regulation of secretion by cell GO:1903530 39 0.327
detection of external stimulus GO:0009581 66 0.325
regulation of organ morphogenesis GO:2000027 78 0.323
organic substance transport GO:0071702 257 0.317
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.315
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.315
Mouse
negative regulation of developmental process GO:0051093 201 0.314
cell division GO:0051301 248 0.313
dendrite development GO:0016358 204 0.302
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.302
Human Mouse
cell migration GO:0016477 238 0.301
death GO:0016265 284 0.301
regulation of intracellular signal transduction GO:1902531 236 0.293
vesicle mediated transport GO:0016192 381 0.289
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.288
cellular response to growth factor stimulus GO:0071363 30 0.287
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.286
morphogenesis of a polarized epithelium GO:0001738 93 0.280
central nervous system development GO:0007417 201 0.279
memory GO:0007613 94 0.278
positive regulation of multicellular organismal process GO:0051240 143 0.275
Human
oocyte anterior posterior axis specification GO:0007314 72 0.271
telencephalon development GO:0021537 2 0.266
wing disc morphogenesis GO:0007472 344 0.266
epithelial cell migration GO:0010631 148 0.266
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.265
Human Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.262
Human Mouse
establishment or maintenance of cell polarity GO:0007163 167 0.259
regulation of cell proliferation GO:0042127 163 0.259
skin development GO:0043588 65 0.254
regulation of cellular component size GO:0032535 98 0.251
regulation of circadian rhythm GO:0042752 49 0.248
response to other organism GO:0051707 293 0.248
embryonic pattern specification GO:0009880 174 0.247
negative regulation of cell communication GO:0010648 223 0.243
localization of cell GO:0051674 257 0.241
aromatic compound catabolic process GO:0019439 166 0.240
columnar cuboidal epithelial cell development GO:0002066 249 0.237
regulation of mapk cascade GO:0043408 92 0.236
regulation of cell death GO:0010941 173 0.235
negative regulation of epithelial cell proliferation GO:0050680 4 0.234
response to wounding GO:0009611 94 0.230
single organism cellular localization GO:1902580 180 0.227
response to external biotic stimulus GO:0043207 293 0.227
r7 cell fate commitment GO:0007465 12 0.226
cellular macromolecule localization GO:0070727 220 0.223
dorsal ventral axon guidance GO:0033563 2 0.220
regulation of cell migration GO:0030334 22 0.218
dorsal ventral axis specification GO:0009950 66 0.217
cell cell signaling involved in cell fate commitment GO:0045168 210 0.216
digestive system development GO:0055123 149 0.214
eye photoreceptor cell fate commitment GO:0042706 37 0.213
positive regulation of signal transduction GO:0009967 223 0.208
protein localization GO:0008104 284 0.198
imaginal disc derived appendage development GO:0048737 399 0.192
embryonic development via the syncytial blastoderm GO:0001700 148 0.186
regulation of epithelial cell proliferation GO:0050678 4 0.185
regulation of cell differentiation GO:0045595 302 0.182
Human
positive regulation of molecular function GO:0044093 136 0.180
neurological system process GO:0050877 358 0.178
regulation of developmental growth GO:0048638 174 0.177
blastoderm segmentation GO:0007350 159 0.175
dendrite morphogenesis GO:0048813 199 0.168
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.167
Mouse
response to organic substance GO:0010033 284 0.166
small molecule metabolic process GO:0044281 305 0.164
long term memory GO:0007616 62 0.163
cell death GO:0008219 279 0.163
defense response to other organism GO:0098542 225 0.162
regulation of circadian sleep wake cycle GO:0042749 25 0.162
positive regulation of neurogenesis GO:0050769 41 0.160
Human
apoptotic process GO:0006915 159 0.158
epithelium migration GO:0090132 148 0.157
kidney development GO:0001822 3 0.156
learning GO:0007612 75 0.156
periodic partitioning GO:0007365 29 0.152
spinal cord development GO:0021510 1 0.150
chemical homeostasis GO:0048878 92 0.144
circadian rhythm GO:0007623 105 0.143
dendrite guidance GO:0070983 21 0.143
purine nucleoside triphosphate metabolic process GO:0009144 119 0.143
tube development GO:0035295 244 0.142
epidermis development GO:0008544 65 0.140
positive regulation of cell migration GO:0030335 2 0.140
immune system process GO:0002376 347 0.140
embryo development ending in birth or egg hatching GO:0009792 152 0.136
response to temperature stimulus GO:0009266 106 0.136
cellular protein modification process GO:0006464 438 0.136
cell cycle phase transition GO:0044770 140 0.135
brain development GO:0007420 120 0.134
stress activated protein kinase signaling cascade GO:0031098 55 0.133
embryonic axis specification GO:0000578 107 0.133
synaptic target recognition GO:0008039 45 0.132
regulation of neuron differentiation GO:0045664 103 0.132
reproductive behavior GO:0019098 122 0.130
negative regulation of stem cell proliferation GO:2000647 30 0.129
catabolic process GO:0009056 409 0.129
aminoglycan biosynthetic process GO:0006023 11 0.129
organophosphate catabolic process GO:0046434 112 0.125
regulation of photoreceptor cell axon guidance GO:2000289 5 0.125
nucleobase containing compound catabolic process GO:0034655 165 0.123
neuron fate commitment GO:0048663 50 0.121
mitotic cell cycle phase transition GO:0044772 138 0.118
morphogenesis of an epithelium GO:0002009 276 0.113
cellular macromolecule catabolic process GO:0044265 136 0.111
regulation of apoptotic process GO:0042981 130 0.110
tissue morphogenesis GO:0048729 297 0.110
wing disc dorsal ventral pattern formation GO:0048190 47 0.109
heart development GO:0007507 82 0.109
regulation of transport GO:0051049 181 0.108
appendage morphogenesis GO:0035107 397 0.107
intracellular transport GO:0046907 228 0.107
endocytosis GO:0006897 310 0.106
notch signaling pathway GO:0007219 120 0.105
regulation of axonogenesis GO:0050770 32 0.104
rna processing GO:0006396 147 0.102
establishment of protein localization GO:0045184 163 0.100
positive regulation of intracellular signal transduction GO:1902533 116 0.099
positive regulation of cell proliferation GO:0008284 47 0.098
ribonucleoside triphosphate catabolic process GO:0009203 108 0.098
positive regulation of cellular biosynthetic process GO:0031328 316 0.097
Mouse
actin filament organization GO:0007015 126 0.097
ras protein signal transduction GO:0007265 88 0.096
negative regulation of neural precursor cell proliferation GO:2000178 27 0.095
negative regulation of cell death GO:0060548 81 0.095
regulation of phosphorus metabolic process GO:0051174 210 0.095
nucleus localization GO:0051647 34 0.094
regulation of phosphorylation GO:0042325 147 0.094
regulation of epithelial cell differentiation GO:0030856 4 0.091
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.091
protein targeting GO:0006605 64 0.090
positive regulation of r7 cell differentiation GO:0045678 7 0.090
cellular response to chemical stimulus GO:0070887 199 0.089
hematopoietic or lymphoid organ development GO:0048534 57 0.089
intracellular protein transport GO:0006886 104 0.088
neuron recognition GO:0008038 101 0.087
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.085
developmental programmed cell death GO:0010623 138 0.085
response to bacterium GO:0009617 198 0.084
detection of light stimulus GO:0009583 58 0.083
single organism behavior GO:0044708 391 0.081
regulation of epithelial cell migration GO:0010632 12 0.080
cellular response to endogenous stimulus GO:0071495 80 0.080
negative regulation of cell cycle GO:0045786 116 0.080
regulation of protein localization GO:0032880 76 0.080
regulation of body fluid levels GO:0050878 14 0.080
phosphorylation GO:0016310 294 0.079
organic substance catabolic process GO:1901575 308 0.077
ovarian follicle cell development GO:0030707 248 0.077
detection of abiotic stimulus GO:0009582 66 0.076
regulation of protein metabolic process GO:0051246 256 0.075
head involution GO:0008258 35 0.075
secretion by cell GO:0032940 101 0.074
cellular nitrogen compound catabolic process GO:0044270 165 0.073
defense response GO:0006952 300 0.072
adipose tissue development GO:0060612 2 0.072
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.070
tissue migration GO:0090130 155 0.070
negative regulation of developmental growth GO:0048640 64 0.069
signal transduction by phosphorylation GO:0023014 107 0.069
germarium derived egg chamber formation GO:0007293 101 0.069
g1 s transition of mitotic cell cycle GO:0000082 31 0.069
regulation of cellular response to stress GO:0080135 89 0.069
photoreceptor cell fate commitment GO:0046552 41 0.069
positive regulation of developmental process GO:0051094 143 0.069
Human
neuroblast fate commitment GO:0014017 19 0.069
immune system development GO:0002520 57 0.069
proteolysis GO:0006508 192 0.068
phagocytosis GO:0006909 215 0.068
digestive tract development GO:0048565 149 0.068
embryonic hemopoiesis GO:0035162 26 0.067
nucleoside phosphate catabolic process GO:1901292 110 0.066
regulation of response to stress GO:0080134 200 0.066
single organism nuclear import GO:1902593 51 0.065
macromolecule catabolic process GO:0009057 161 0.065
intracellular signal transduction GO:0035556 300 0.063
organic cyclic compound catabolic process GO:1901361 168 0.063
male gamete generation GO:0048232 201 0.062
purine nucleotide catabolic process GO:0006195 109 0.062
cell motility GO:0048870 251 0.061
organ growth GO:0035265 56 0.061
circulatory system development GO:0072359 82 0.061
regulation of cell cycle phase transition GO:1901987 130 0.060
camera type eye development GO:0043010 4 0.060
regulation of neuroblast proliferation GO:1902692 34 0.060
negative regulation of cellular metabolic process GO:0031324 382 0.060
Human Mouse
synaptic transmission GO:0007268 288 0.058
protein transport GO:0015031 155 0.057
heart morphogenesis GO:0003007 32 0.057
heterocycle catabolic process GO:0046700 166 0.057
hemocyte differentiation GO:0042386 38 0.055
small gtpase mediated signal transduction GO:0007264 88 0.055
regulation of cell projection organization GO:0031344 92 0.055
positive regulation of nervous system development GO:0051962 69 0.054
Human
defense response to bacterium GO:0042742 178 0.053
cytoplasm organization GO:0007028 64 0.053
olfactory bulb axon guidance GO:0071678 3 0.053
eggshell formation GO:0030703 105 0.053
cellular response to organic substance GO:0071310 132 0.052
establishment of protein localization to organelle GO:0072594 62 0.052
positive regulation of cell development GO:0010720 61 0.052
Human
water homeostasis GO:0030104 3 0.051
regulation of immune system process GO:0002682 176 0.050
regulation of actin filament length GO:0030832 27 0.050
nephron tubule development GO:0072080 3 0.050
defense response to fungus GO:0050832 48 0.050
cardiac cell fate commitment GO:0060911 17 0.050
retina development in camera type eye GO:0060041 4 0.049
cytoplasmic transport GO:0016482 130 0.048
renal system development GO:0072001 72 0.048
maintenance of gastrointestinal epithelium GO:0030277 3 0.048
compound eye photoreceptor fate commitment GO:0001752 36 0.047
connective tissue development GO:0061448 3 0.047
positive regulation of cell projection organization GO:0031346 29 0.046
ameboidal type cell migration GO:0001667 151 0.046
organelle assembly GO:0070925 198 0.046
extrinsic apoptotic signaling pathway GO:0097191 1 0.046
negative regulation of signal transduction GO:0009968 206 0.046
hippo signaling GO:0035329 20 0.045
epidermal growth factor receptor signaling pathway GO:0007173 58 0.045
carbohydrate derivative metabolic process GO:1901135 217 0.045
morphogenesis of embryonic epithelium GO:0016331 94 0.045
camera type eye morphogenesis GO:0048593 2 0.045
mesoderm development GO:0007498 78 0.044
regulation of neural precursor cell proliferation GO:2000177 35 0.044
epithelial cell proliferation GO:0050673 15 0.044
pole plasm oskar mrna localization GO:0045451 46 0.044
establishment of nucleus localization GO:0040023 26 0.043
detection of stimulus involved in sensory perception GO:0050906 92 0.043
myoblast fusion GO:0007520 43 0.043
stem cell fate commitment GO:0048865 25 0.043
actin polymerization or depolymerization GO:0008154 31 0.043
erbb signaling pathway GO:0038127 58 0.043
stem cell maintenance GO:0019827 67 0.042
renal filtration cell differentiation GO:0061318 12 0.042
semaphorin plexin signaling pathway GO:0071526 4 0.042
regulation of cell division GO:0051302 72 0.042
response to nitrogen compound GO:1901698 90 0.042
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.042
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.042
response to oxygen containing compound GO:1901700 200 0.042
organonitrogen compound metabolic process GO:1901564 318 0.042
negative regulation of cell development GO:0010721 62 0.041
protein phosphorylation GO:0006468 169 0.041
positive regulation of signaling GO:0023056 243 0.040
peptidyl amino acid modification GO:0018193 105 0.040
imaginal disc derived leg morphogenesis GO:0007480 80 0.040
regulation of multicellular organism growth GO:0040014 40 0.040
negative regulation of gene expression epigenetic GO:0045814 77 0.040
secretion GO:0046903 109 0.039
positive regulation of cell motility GO:2000147 3 0.039
regulation of molecular function GO:0065009 217 0.039
posttranscriptional regulation of gene expression GO:0010608 145 0.039
multicellular organismal homeostasis GO:0048871 41 0.039
positive regulation of cell communication GO:0010647 250 0.039
regulation of cell cycle GO:0051726 291 0.039
regulation of malpighian tubule diameter GO:0035297 3 0.039
neuromuscular junction development GO:0007528 149 0.038
negative regulation of neurogenesis GO:0050768 53 0.038
response to growth factor GO:0070848 31 0.038
negative regulation of programmed cell death GO:0043069 72 0.037
response to lipopolysaccharide GO:0032496 4 0.037
olfactory learning GO:0008355 56 0.037
protein ubiquitination GO:0016567 70 0.037
axon extension involved in axon guidance GO:0048846 10 0.036
regulation of eye photoreceptor cell development GO:0042478 13 0.036
cellular protein localization GO:0034613 160 0.036
regulation of nurse cell apoptotic process GO:0045477 9 0.036
cellular chemical homeostasis GO:0055082 40 0.036
regulation of mitotic cell cycle GO:0007346 190 0.035
regulation of protein import into nucleus GO:0042306 28 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.035
cell type specific apoptotic process GO:0097285 38 0.034
positive regulation of epithelial cell differentiation GO:0030858 1 0.034
positive regulation of developmental growth GO:0048639 62 0.034
embryonic organ morphogenesis GO:0048562 5 0.034
positive regulation of axon extension GO:0045773 2 0.034
multi multicellular organism process GO:0044706 123 0.034
regulation of cell motility GO:2000145 23 0.033
nucleoside catabolic process GO:0009164 112 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.033
actin filament polymerization GO:0030041 27 0.033
regulation of catabolic process GO:0009894 170 0.033
regulation of cellular component biogenesis GO:0044087 201 0.033
ribonucleoside triphosphate metabolic process GO:0009199 119 0.033
regulation of compound eye photoreceptor development GO:0045314 12 0.033
multi organism behavior GO:0051705 175 0.033
mitotic nuclear division GO:0007067 213 0.033
stem cell proliferation GO:0072089 88 0.033
axonal fasciculation GO:0007413 12 0.032
nucleocytoplasmic transport GO:0006913 72 0.032
programmed cell death GO:0012501 257 0.032
regulation of protein localization to nucleus GO:1900180 29 0.032
peripheral nervous system development GO:0007422 52 0.032
regulation of cell cycle process GO:0010564 181 0.032
chaeta development GO:0022416 97 0.031
wound healing GO:0042060 75 0.031
regulation of hydrolase activity GO:0051336 97 0.031
synapse organization GO:0050808 196 0.031
instar larval development GO:0002168 55 0.031
positive regulation of immune response GO:0050778 63 0.031
regulation of cellular component movement GO:0051270 42 0.031
regulation of neuron projection development GO:0010975 69 0.030
axon extension GO:0048675 32 0.030
regulation of establishment of protein localization GO:0070201 61 0.030
pole plasm mrna localization GO:0019094 49 0.030
chromosome segregation GO:0007059 157 0.030
positive regulation of axonogenesis GO:0050772 2 0.030
imaginal disc derived wing morphogenesis GO:0007476 337 0.030
negative regulation of nervous system development GO:0051961 92 0.030
body morphogenesis GO:0010171 2 0.030
regulation of actin polymerization or depolymerization GO:0008064 27 0.029
germ band shortening GO:0007390 19 0.029
purine nucleoside catabolic process GO:0006152 112 0.029
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.029
response to abiotic stimulus GO:0009628 341 0.029
regulation of ras protein signal transduction GO:0046578 93 0.029
regulation of notch signaling pathway GO:0008593 100 0.028
nucleotide catabolic process GO:0009166 109 0.027
regulation of erbb signaling pathway GO:1901184 42 0.027
negative regulation of neuroblast proliferation GO:0007406 27 0.027
regulation of dendrite development GO:0050773 37 0.027
growth GO:0040007 359 0.027
imaginal disc growth GO:0007446 37 0.027
nephron epithelium morphogenesis GO:0072088 3 0.027
negative regulation of cell cycle phase transition GO:1901988 103 0.026
regulation of gtp catabolic process GO:0033124 44 0.026
organelle localization GO:0051640 148 0.026
regulation of system process GO:0044057 36 0.026
substrate dependent cell migration cell extension GO:0006930 3 0.026
purine nucleotide metabolic process GO:0006163 146 0.026
tube morphogenesis GO:0035239 191 0.026
regulation of cell fate specification GO:0042659 27 0.025
single organism catabolic process GO:0044712 228 0.025
i kappab phosphorylation GO:0007252 3 0.025
regulation of anatomical structure size GO:0090066 163 0.025
cellular response to biotic stimulus GO:0071216 4 0.025
regulation of response to external stimulus GO:0032101 115 0.025
apoptotic signaling pathway GO:0097190 27 0.025
protein localization to nucleus GO:0034504 55 0.025
positive regulation of programmed cell death GO:0043068 62 0.025
protein import into nucleus GO:0006606 51 0.025
g protein coupled receptor signaling pathway GO:0007186 136 0.024
polarized epithelial cell differentiation GO:0030859 10 0.024
pole plasm assembly GO:0007315 61 0.024
regulation of small gtpase mediated signal transduction GO:0051056 93 0.024
microtubule based movement GO:0007018 51 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.024
ion transmembrane transport GO:0034220 122 0.024
cellular response to dna damage stimulus GO:0006974 223 0.024
organonitrogen compound catabolic process GO:1901565 128 0.024
blood circulation GO:0008015 26 0.024
ribonucleotide catabolic process GO:0009261 109 0.024
cell cycle g1 s phase transition GO:0044843 31 0.024
regulation of cytoskeleton organization GO:0051493 89 0.024
atp catabolic process GO:0006200 38 0.024
nephron tubule morphogenesis GO:0072078 3 0.024
exocytosis GO:0006887 28 0.024
r3 r4 cell fate commitment GO:0007464 10 0.023
purine ribonucleoside catabolic process GO:0046130 112 0.023
meiotic cell cycle GO:0051321 171 0.023
regulation of stem cell proliferation GO:0072091 40 0.023
macromolecular complex assembly GO:0065003 256 0.023
actin filament based process GO:0030029 220 0.023
positive regulation of defense response GO:0031349 59 0.023
protein localization to organelle GO:0033365 82 0.023
meiotic cell cycle process GO:1903046 132 0.023
regulation of axon extension involved in axon guidance GO:0048841 4 0.023
cellular response to abiotic stimulus GO:0071214 58 0.022
single organism carbohydrate metabolic process GO:0044723 72 0.022
epithelial cell migration open tracheal system GO:0007427 32 0.022
guanosine containing compound catabolic process GO:1901069 74 0.022
oocyte fate determination GO:0030716 27 0.022
dna metabolic process GO:0006259 227 0.022
establishment of ommatidial planar polarity GO:0042067 49 0.022
regulation of cell substrate adhesion GO:0010810 2 0.022
response to light stimulus GO:0009416 124 0.022
regulation of organ growth GO:0046620 42 0.022
purine containing compound catabolic process GO:0072523 112 0.021
purine ribonucleotide catabolic process GO:0009154 109 0.021
positive regulation of response to stimulus GO:0048584 323 0.021
positive regulation of growth GO:0045927 75 0.021
positive regulation of multi organism process GO:0043902 40 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
ribonucleoside monophosphate metabolic process GO:0009161 51 0.021
positive regulation of cellular component biogenesis GO:0044089 80 0.021
positive regulation of immune system process GO:0002684 68 0.021
neural retina development GO:0003407 4 0.021

spen disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
sensory system disease DOID:0050155 0 0.046
eye and adnexa disease DOID:1492 0 0.046
nervous system disease DOID:863 0 0.046