Drosophila melanogaster

40 known processes

mus205 (Dmel_CG1925)

mutagen-sensitive 205

(Aliases: Dmel\CG1925,AAF59191,CG1925,Dmpolzeta,DhRev3,mus 205,mus-205,DmREV3,154926_at,mus(2)205)

mus205 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 54 0.999
double strand break repair GO:0006302 26 0.999
dna recombination GO:0006310 32 0.999
double strand break repair via homologous recombination GO:0000724 13 0.998
cellular response to dna damage stimulus GO:0006974 223 0.998
double strand break repair via nonhomologous end joining GO:0006303 5 0.998
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.996
non recombinational repair GO:0000726 7 0.991
mitotic dna damage checkpoint GO:0044773 74 0.984
recombinational repair GO:0000725 13 0.982
dna damage checkpoint GO:0000077 78 0.981
mitotic dna integrity checkpoint GO:0044774 75 0.979
nucleotide excision repair GO:0006289 8 0.975
dna synthesis involved in dna repair GO:0000731 5 0.968
dna double strand break processing GO:0000729 3 0.866
mitotic cell cycle checkpoint GO:0007093 88 0.793
postreplication repair GO:0006301 2 0.744
mitotic cell cycle phase transition GO:0044772 138 0.741
negative regulation of cell cycle phase transition GO:1901988 103 0.731
mitotic g2 dna damage checkpoint GO:0007095 69 0.719
response to radiation GO:0009314 155 0.714
dna metabolic process GO:0006259 227 0.685
mitotic g2 m transition checkpoint GO:0044818 70 0.685
mitotic recombination GO:0006312 2 0.657
telomere maintenance via recombination GO:0000722 1 0.652
translesion synthesis GO:0019985 2 0.645
negative regulation of cell cycle process GO:0010948 109 0.589
dna integrity checkpoint GO:0031570 81 0.588
telomere maintenance GO:0000723 21 0.584
meiosis i GO:0007127 59 0.566
reciprocal meiotic recombination GO:0007131 19 0.564
response to uv GO:0009411 24 0.561
response to ionizing radiation GO:0010212 32 0.557
meiotic nuclear division GO:0007126 151 0.532
telomere organization GO:0032200 21 0.516
negative regulation of mitotic cell cycle GO:0045930 109 0.511
meiotic cell cycle process GO:1903046 132 0.508
cell cycle checkpoint GO:0000075 95 0.480
g2 dna damage checkpoint GO:0031572 69 0.480
meiotic chromosome segregation GO:0045132 59 0.473
regulation of cell cycle phase transition GO:1901987 130 0.470
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.454
chromosome organization GO:0051276 360 0.443
cellular response to radiation GO:0071478 52 0.421
negative regulation of cell cycle GO:0045786 116 0.392
regulation of cellular response to stress GO:0080135 89 0.372
regulation of dna recombination GO:0000018 4 0.369
regulation of dna repair GO:0006282 5 0.347
response to nitrogen compound GO:1901698 90 0.346
dna biosynthetic process GO:0071897 24 0.343
regulation of cell cycle process GO:0010564 181 0.342
response to alkaloid GO:0043279 26 0.322
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.306
purine containing compound metabolic process GO:0072521 155 0.289
response to organonitrogen compound GO:0010243 75 0.276
cell cycle phase transition GO:0044770 140 0.274
regulation of mitotic cell cycle phase transition GO:1901990 130 0.269
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.261
purine ribonucleoside metabolic process GO:0046128 127 0.258
response to light stimulus GO:0009416 124 0.238
purine nucleoside catabolic process GO:0006152 112 0.237
dna geometric change GO:0032392 16 0.228
regulation of response to dna damage stimulus GO:2001020 23 0.223
nucleoside triphosphate catabolic process GO:0009143 108 0.206
regulation of mitotic cell cycle GO:0007346 190 0.201
meiotic cell cycle GO:0051321 171 0.201
ribonucleoside metabolic process GO:0009119 127 0.199
ribonucleoside catabolic process GO:0042454 112 0.197
nucleoside triphosphate metabolic process GO:0009141 120 0.190
nucleobase containing compound catabolic process GO:0034655 165 0.176
organelle fission GO:0048285 340 0.172
aging GO:0007568 143 0.172
phosphorylation GO:0016310 294 0.171
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.171
response to organic substance GO:0010033 284 0.162
ribonucleoside triphosphate catabolic process GO:0009203 108 0.159
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.157
response to oxygen containing compound GO:1901700 200 0.155
response to abiotic stimulus GO:0009628 341 0.152
organophosphate metabolic process GO:0019637 195 0.146
glycosyl compound catabolic process GO:1901658 112 0.145
atp metabolic process GO:0046034 49 0.144
regulation of cell cycle GO:0051726 291 0.141
nucleoside metabolic process GO:0009116 127 0.140
cellular protein modification process GO:0006464 438 0.139
homeostatic process GO:0042592 199 0.138
reciprocal dna recombination GO:0035825 19 0.138
response to endogenous stimulus GO:0009719 119 0.137
regulation of double strand break repair GO:2000779 3 0.134
ribonucleotide catabolic process GO:0009261 109 0.132
multicellular organismal aging GO:0010259 140 0.131
purine nucleoside triphosphate catabolic process GO:0009146 108 0.129
organic cyclic compound catabolic process GO:1901361 168 0.128
cellular catabolic process GO:0044248 372 0.125
protein phosphorylation GO:0006468 169 0.123
cellular response to gamma radiation GO:0071480 10 0.123
purine nucleotide catabolic process GO:0006195 109 0.123
ribonucleotide metabolic process GO:0009259 145 0.123
purine nucleotide metabolic process GO:0006163 146 0.120
purine ribonucleotide catabolic process GO:0009154 109 0.118
purine nucleoside triphosphate metabolic process GO:0009144 119 0.116
death GO:0016265 284 0.116
purine containing compound catabolic process GO:0072523 112 0.115
chromatin organization GO:0006325 207 0.115
organonitrogen compound metabolic process GO:1901564 318 0.114
nucleobase containing small molecule metabolic process GO:0055086 174 0.111
growth GO:0040007 359 0.110
immune system process GO:0002376 347 0.109
nucleotide catabolic process GO:0009166 109 0.108
nucleoside phosphate catabolic process GO:1901292 110 0.106
chromosome segregation GO:0007059 157 0.105
glycosyl compound metabolic process GO:1901657 127 0.104
purine nucleoside metabolic process GO:0042278 127 0.103
ribonucleoside monophosphate metabolic process GO:0009161 51 0.101
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.100
response to x ray GO:0010165 8 0.098
positive regulation of rna biosynthetic process GO:1902680 266 0.096
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.095
carbohydrate derivative metabolic process GO:1901135 217 0.094
nucleoside phosphate metabolic process GO:0006753 162 0.092
small molecule metabolic process GO:0044281 305 0.090
signal transduction in response to dna damage GO:0042770 3 0.090
heterocycle catabolic process GO:0046700 166 0.089
carbohydrate derivative catabolic process GO:1901136 118 0.088
aromatic compound catabolic process GO:0019439 166 0.086
purine ribonucleotide metabolic process GO:0009150 145 0.085
nucleotide metabolic process GO:0009117 161 0.084
negative regulation of response to stimulus GO:0048585 258 0.083
organonitrogen compound catabolic process GO:1901565 128 0.082
ribonucleoside triphosphate metabolic process GO:0009199 119 0.081
anatomical structure homeostasis GO:0060249 97 0.080
catabolic process GO:0009056 409 0.080
response to caffeine GO:0031000 12 0.080
cell death GO:0008219 279 0.080
negative regulation of cell communication GO:0010648 223 0.078
organic substance catabolic process GO:1901575 308 0.077
nucleoside catabolic process GO:0009164 112 0.076
oocyte fate determination GO:0030716 27 0.075
cellular nitrogen compound catabolic process GO:0044270 165 0.075
regulation of programmed cell death GO:0043067 152 0.075
cellular response to chemical stimulus GO:0070887 199 0.074
regulation of cell differentiation GO:0045595 302 0.073
purine nucleoside monophosphate catabolic process GO:0009128 38 0.073
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.071
dna replication GO:0006260 48 0.070
regulation of response to stress GO:0080134 200 0.068
hemopoiesis GO:0030097 46 0.068
cellular response to organic substance GO:0071310 132 0.068
dna catabolic process GO:0006308 16 0.067
purine ribonucleoside catabolic process GO:0046130 112 0.067
regulation of cell cycle g1 s phase transition GO:1902806 23 0.066
female meiotic division GO:0007143 70 0.066
intrinsic apoptotic signaling pathway GO:0097193 16 0.065
organophosphate catabolic process GO:0046434 112 0.065
intracellular signal transduction GO:0035556 300 0.065
single organism catabolic process GO:0044712 228 0.064
regulation of dna metabolic process GO:0051052 34 0.063
cell aging GO:0007569 2 0.063
cellular macromolecule localization GO:0070727 220 0.061
cellular response to organonitrogen compound GO:0071417 36 0.060
cellular response to abiotic stimulus GO:0071214 58 0.060
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.059
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.059
apoptotic process GO:0006915 159 0.058
regulation of cellular protein metabolic process GO:0032268 243 0.057
developmental growth GO:0048589 280 0.057
cellular response to ionizing radiation GO:0071479 15 0.057
body morphogenesis GO:0010171 2 0.056
single organism biosynthetic process GO:0044711 206 0.056
nucleoside monophosphate metabolic process GO:0009123 52 0.056
cellular response to oxygen containing compound GO:1901701 79 0.055
positive regulation of nucleic acid templated transcription GO:1903508 266 0.054
regulation of cell death GO:0010941 173 0.054
purine nucleoside monophosphate metabolic process GO:0009126 50 0.053
protein modification process GO:0036211 438 0.051
positive regulation of cellular biosynthetic process GO:0031328 316 0.045
immune response GO:0006955 246 0.045
dna dependent dna replication GO:0006261 17 0.045
mitotic nuclear division GO:0007067 213 0.044
regulation of phosphorylation GO:0042325 147 0.044
programmed cell death GO:0012501 257 0.043
neurological system process GO:0050877 358 0.043
atp catabolic process GO:0006200 38 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
enzyme linked receptor protein signaling pathway GO:0007167 179 0.041
determination of adult lifespan GO:0008340 137 0.041
positive regulation of rna metabolic process GO:0051254 271 0.041
response to purine containing compound GO:0014074 12 0.040
regulation of system process GO:0044057 36 0.039
positive regulation of developmental process GO:0051094 143 0.038
regulation of multicellular organismal development GO:2000026 414 0.038
single organism intracellular transport GO:1902582 207 0.037
positive regulation of multicellular organismal process GO:0051240 143 0.036
polarity specification of dorsal ventral axis GO:0009951 6 0.035
immune system development GO:0002520 57 0.035
regulation of molecular function GO:0065009 217 0.034
positive regulation of transcription dna templated GO:0045893 266 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
eye development GO:0001654 323 0.034
dorsal ventral pattern formation GO:0009953 133 0.033
regulation of phosphorus metabolic process GO:0051174 210 0.033
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.033
positive regulation of signaling GO:0023056 243 0.033
meiotic chromosome separation GO:0051307 8 0.033
positive regulation of biosynthetic process GO:0009891 316 0.033
regionalization GO:0003002 416 0.032
cell proliferation GO:0008283 299 0.032
cell cycle g1 s phase transition GO:0044843 31 0.032
negative regulation of cell death GO:0060548 81 0.031
transmembrane transport GO:0055085 139 0.031
negative regulation of signal transduction GO:0009968 206 0.031
mrna splicing via spliceosome GO:0000398 73 0.031
regulation of cellular ketone metabolic process GO:0010565 3 0.030
regulation of protein metabolic process GO:0051246 256 0.030
cellular response to nitrogen compound GO:1901699 51 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
hematopoietic or lymphoid organ development GO:0048534 57 0.029
cellular amino acid metabolic process GO:0006520 61 0.029
regulation of protein modification process GO:0031399 112 0.029
ribose phosphate metabolic process GO:0019693 145 0.028
positive regulation of programmed cell death GO:0043068 62 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.028
nuclear division GO:0000280 332 0.028
photoreceptor cell development GO:0042461 96 0.028
cytoplasmic transport GO:0016482 130 0.028
establishment of localization in cell GO:0051649 402 0.028
regulation of developmental growth GO:0048638 174 0.027
regulation of rna splicing GO:0043484 69 0.027
histone modification GO:0016570 106 0.027
wing disc morphogenesis GO:0007472 344 0.027
carboxylic acid metabolic process GO:0019752 92 0.027
cellular macromolecule catabolic process GO:0044265 136 0.026
multicellular organismal homeostasis GO:0048871 41 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.026
embryo development ending in birth or egg hatching GO:0009792 152 0.025
germarium derived egg chamber formation GO:0007293 101 0.025
ribonucleoside monophosphate catabolic process GO:0009158 39 0.025
response to organic cyclic compound GO:0014070 89 0.025
cell motility GO:0048870 251 0.025
amine metabolic process GO:0009308 12 0.025
regulation of kinase activity GO:0043549 53 0.025
positive regulation of cell communication GO:0010647 250 0.024
organelle assembly GO:0070925 198 0.024
regulation of intracellular signal transduction GO:1902531 236 0.024
regulation of catalytic activity GO:0050790 185 0.024
response to camptothecin GO:1901563 2 0.023
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.022
nucleoside monophosphate catabolic process GO:0009125 39 0.022
compound eye development GO:0048749 307 0.021
cellular ketone metabolic process GO:0042180 24 0.021
anterior posterior pattern specification GO:0009952 136 0.021
regulation of synaptic transmission GO:0050804 69 0.021
negative regulation of signaling GO:0023057 219 0.021
covalent chromatin modification GO:0016569 106 0.021
mitotic dna replication checkpoint GO:0033314 5 0.021
alternative mrna splicing via spliceosome GO:0000380 60 0.020
positive regulation of signal transduction GO:0009967 223 0.020
axonogenesis GO:0007409 290 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
negative regulation of biosynthetic process GO:0009890 277 0.020
g1 s transition of mitotic cell cycle GO:0000082 31 0.020
karyosome formation GO:0030717 22 0.019
positive regulation of gene expression GO:0010628 290 0.019
mrna processing GO:0006397 104 0.019
intracellular transport GO:0046907 228 0.019
chromatin remodeling GO:0006338 72 0.019
cellular amine metabolic process GO:0044106 12 0.019
regulation of mrna splicing via spliceosome GO:0048024 64 0.019
regulation of protein phosphorylation GO:0001932 64 0.019
cell migration GO:0016477 238 0.019
positive regulation of peptidase activity GO:0010952 29 0.019
axis specification GO:0009798 167 0.018
cilium morphogenesis GO:0060271 39 0.018
regulation of growth GO:0040008 233 0.018
regulation of mapk cascade GO:0043408 92 0.018
negative regulation of dna metabolic process GO:0051053 12 0.018
ion transport GO:0006811 145 0.017
epidermis development GO:0008544 65 0.017
cell cycle arrest GO:0007050 4 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
rna splicing via transesterification reactions GO:0000375 73 0.017
dendrite development GO:0016358 204 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
vesicle mediated transport GO:0016192 381 0.016
regulation of anatomical structure size GO:0090066 163 0.016
oxoacid metabolic process GO:0043436 103 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
macromolecular complex assembly GO:0065003 256 0.016
regulation of endopeptidase activity GO:0052548 36 0.016
peptidyl amino acid modification GO:0018193 105 0.015
protein complex biogenesis GO:0070271 201 0.015
multi organism behavior GO:0051705 175 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
regulation of apoptotic process GO:0042981 130 0.015
regulation of neurogenesis GO:0050767 158 0.015
rna splicing GO:0008380 83 0.015
response to toxic substance GO:0009636 22 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
compound eye morphogenesis GO:0001745 249 0.014
germarium derived oocyte fate determination GO:0007294 26 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
apoptotic signaling pathway GO:0097190 27 0.014
regulation of mrna metabolic process GO:1903311 72 0.014
response to gamma radiation GO:0010332 17 0.014
response to organophosphorus GO:0046683 2 0.014
female meiosis chromosome segregation GO:0016321 33 0.014
macromolecule catabolic process GO:0009057 161 0.014
regulation of phosphatase activity GO:0010921 3 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
chromatin modification GO:0016568 147 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
positive regulation of molecular function GO:0044093 136 0.013
protein dna complex subunit organization GO:0071824 86 0.013
rna localization GO:0006403 115 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.013
male gamete generation GO:0048232 201 0.013
regulation of double strand break repair via homologous recombination GO:0010569 2 0.013
regulation of cell development GO:0060284 215 0.013
response to alcohol GO:0097305 95 0.012
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
gtp catabolic process GO:0006184 72 0.012
single organism cellular localization GO:1902580 180 0.012
wound healing GO:0042060 75 0.012
protein complex assembly GO:0006461 200 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
polarity specification of anterior posterior axis GO:0009949 5 0.012
cell type specific apoptotic process GO:0097285 38 0.012
proteolysis GO:0006508 192 0.012
cellular response to insulin stimulus GO:0032869 28 0.011
sensory perception GO:0007600 196 0.011
regulation of nervous system development GO:0051960 248 0.011
somatic cell dna recombination GO:0016444 1 0.011
organic acid metabolic process GO:0006082 103 0.011
dorsal ventral axis specification GO:0009950 66 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
anterior posterior axis specification GO:0009948 109 0.011
response to wounding GO:0009611 94 0.011
defense response to other organism GO:0098542 225 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
developmental programmed cell death GO:0010623 138 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
embryonic morphogenesis GO:0048598 206 0.010
thermotaxis GO:0043052 16 0.010
gtp metabolic process GO:0046039 72 0.010
larval development GO:0002164 104 0.010

mus205 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
thoracic cancer DOID:5093 0 0.078
cancer DOID:162 0 0.078
disease of cellular proliferation DOID:14566 0 0.078
organ system cancer DOID:0050686 0 0.078
disease of anatomical entity DOID:7 0 0.058
breast cancer DOID:1612 0 0.020
nervous system disease DOID:863 0 0.015