Drosophila melanogaster

40 known processes

sip3 (Dmel_CG1937)

septin interacting protein 3

(Aliases: CG1937,Hrd1,HRD1,dSyno,Dmel\CG1937)

sip3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
death GO:0016265 284 0.061
Mouse
catabolic process GO:0009056 409 0.054
Human
organic substance catabolic process GO:1901575 308 0.050
Human
vesicle mediated transport GO:0016192 381 0.050
defense response GO:0006952 300 0.045
response to other organism GO:0051707 293 0.042
organonitrogen compound metabolic process GO:1901564 318 0.042
cellular catabolic process GO:0044248 372 0.041
Human
regulation of protein metabolic process GO:0051246 256 0.040
endocytosis GO:0006897 310 0.039
regulation of cell death GO:0010941 173 0.038
Mouse
cellular protein modification process GO:0006464 438 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.034
regulation of cellular ketone metabolic process GO:0010565 3 0.032
small molecule metabolic process GO:0044281 305 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.031
response to biotic stimulus GO:0009607 294 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.031
regulation of catalytic activity GO:0050790 185 0.030
regulation of cellular protein metabolic process GO:0032268 243 0.029
cell death GO:0008219 279 0.029
Mouse
negative regulation of gene expression GO:0010629 387 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.028
dna metabolic process GO:0006259 227 0.028
immune system process GO:0002376 347 0.028
programmed cell death GO:0012501 257 0.028
Mouse
cellular amino acid metabolic process GO:0006520 61 0.028
regulation of immune system process GO:0002682 176 0.028
amine metabolic process GO:0009308 12 0.028
positive regulation of rna metabolic process GO:0051254 271 0.028
nucleobase containing compound catabolic process GO:0034655 165 0.028
proteolysis GO:0006508 192 0.027
Human
response to external biotic stimulus GO:0043207 293 0.027
regulation of molecular function GO:0065009 217 0.027
protein modification process GO:0036211 438 0.027
organophosphate metabolic process GO:0019637 195 0.026
protein phosphorylation GO:0006468 169 0.026
apoptotic process GO:0006915 159 0.025
Mouse
response to bacterium GO:0009617 198 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.025
protein modification by small protein conjugation or removal GO:0070647 106 0.025
gland development GO:0048732 191 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
oxoacid metabolic process GO:0043436 103 0.024
negative regulation of signaling GO:0023057 219 0.024
Mouse
positive regulation of response to stimulus GO:0048584 323 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
negative regulation of cellular protein metabolic process GO:0032269 85 0.024
positive regulation of signal transduction GO:0009967 223 0.024
positive regulation of biosynthetic process GO:0009891 316 0.024
regulation of intracellular signal transduction GO:1902531 236 0.024
Mouse
phosphorylation GO:0016310 294 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
posttranscriptional regulation of gene expression GO:0010608 145 0.023
tube development GO:0035295 244 0.023
negative regulation of signal transduction GO:0009968 206 0.023
Mouse
negative regulation of cell communication GO:0010648 223 0.023
Mouse
aromatic compound catabolic process GO:0019439 166 0.023
regulation of apoptotic process GO:0042981 130 0.023
Mouse
peptidyl amino acid modification GO:0018193 105 0.023
Human
immune response GO:0006955 246 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
cuticle development GO:0042335 86 0.022
negative regulation of developmental process GO:0051093 201 0.022
response to abiotic stimulus GO:0009628 341 0.022
organic acid metabolic process GO:0006082 103 0.022
nucleoside metabolic process GO:0009116 127 0.022
regulation of cell differentiation GO:0045595 302 0.022
regulation of organelle organization GO:0033043 196 0.022
heterocycle catabolic process GO:0046700 166 0.022
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
regulation of programmed cell death GO:0043067 152 0.021
Mouse
microtubule organizing center organization GO:0031023 168 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.021
positive regulation of proteolysis GO:0045862 52 0.021
regulation of proteolysis GO:0030162 87 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
organic cyclic compound catabolic process GO:1901361 168 0.020
regulation of catabolic process GO:0009894 170 0.020
notch signaling pathway GO:0007219 120 0.020
positive regulation of cell communication GO:0010647 250 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
single organism catabolic process GO:0044712 228 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
regulation of gene expression epigenetic GO:0040029 128 0.019
cellular ketone metabolic process GO:0042180 24 0.019
positive regulation of cellular component organization GO:0051130 156 0.019
protein maturation GO:0051604 71 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
defense response to bacterium GO:0042742 178 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
larval development GO:0002164 104 0.018
phagocytosis GO:0006909 215 0.018
embryonic development via the syncytial blastoderm GO:0001700 148 0.017
response to wounding GO:0009611 94 0.017
glycosyl compound metabolic process GO:1901657 127 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
single organism behavior GO:0044708 391 0.017
purine containing compound metabolic process GO:0072521 155 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
body morphogenesis GO:0010171 2 0.017
response to temperature stimulus GO:0009266 106 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
regulation of transport GO:0051049 181 0.016
gtp metabolic process GO:0046039 72 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
sensory perception of pain GO:0019233 4 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
cellular amine metabolic process GO:0044106 12 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
Mouse
negative regulation of organelle organization GO:0010639 56 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
regulation of endopeptidase activity GO:0052548 36 0.016
defense response to other organism GO:0098542 225 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
cellular macromolecule localization GO:0070727 220 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
regulation of phosphorylation GO:0042325 147 0.015
protein ubiquitination GO:0016567 70 0.015
nucleotide metabolic process GO:0009117 161 0.015
embryonic morphogenesis GO:0048598 206 0.015
detection of stimulus involved in sensory perception GO:0050906 92 0.015
g protein coupled receptor signaling pathway GO:0007186 136 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
regulation of localization GO:0032879 275 0.015
protein processing GO:0016485 68 0.015
regulation of peptidase activity GO:0052547 39 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
Human
appendage development GO:0048736 401 0.015
positive regulation of gene expression GO:0010628 290 0.015
salivary gland development GO:0007431 162 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
negative regulation of cell death GO:0060548 81 0.014
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
regulation of cell cycle GO:0051726 291 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
response to light stimulus GO:0009416 124 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.014
instar larval development GO:0002168 55 0.014
respiratory system development GO:0060541 213 0.014
appendage morphogenesis GO:0035107 397 0.014
intracellular signal transduction GO:0035556 300 0.014
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
protein modification by small protein conjugation GO:0032446 79 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
chemosensory behavior GO:0007635 106 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
anatomical structure homeostasis GO:0060249 97 0.014
positive regulation of molecular function GO:0044093 136 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
regulation of defense response GO:0031347 102 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
wing disc morphogenesis GO:0007472 344 0.013
regulation of nervous system development GO:0051960 248 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
positive regulation of signaling GO:0023056 243 0.013
nuclear division GO:0000280 332 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
organic substance transport GO:0071702 257 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
exocrine system development GO:0035272 162 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
positive regulation of protein modification process GO:0031401 58 0.012
spindle organization GO:0007051 253 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.012
centrosome organization GO:0051297 163 0.012
protein localization GO:0008104 284 0.012
positive regulation of transport GO:0051050 92 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
intracellular transport GO:0046907 228 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
organelle fission GO:0048285 340 0.012
establishment of localization in cell GO:0051649 402 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
nucleoside catabolic process GO:0009164 112 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.012
eye development GO:0001654 323 0.012
axon development GO:0061564 297 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
mitotic spindle organization GO:0007052 220 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
response to radiation GO:0009314 155 0.012
single organism cellular localization GO:1902580 180 0.012
regulation of gtp catabolic process GO:0033124 44 0.012
gene silencing GO:0016458 138 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
localization of cell GO:0051674 257 0.012
protein kinase b signaling GO:0043491 1 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
establishment of protein localization GO:0045184 163 0.012
positive regulation of cell death GO:0010942 69 0.012
negative regulation of transcription dna templated GO:0045892 237 0.011
response to lipopolysaccharide GO:0032496 4 0.011
head development GO:0060322 135 0.011
purine containing compound catabolic process GO:0072523 112 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
multicellular organismal aging GO:0010259 140 0.011
single organism intracellular transport GO:1902582 207 0.011
regulation of mitochondrion organization GO:0010821 12 0.011
positive regulation of calcium ion transport GO:0051928 4 0.011
negative regulation of cellular catabolic process GO:0031330 34 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.011
regulation of protein modification process GO:0031399 112 0.011
cell proliferation GO:0008283 299 0.011
regulation of transferase activity GO:0051338 58 0.011
lateral inhibition GO:0046331 206 0.011
epithelial cell differentiation GO:0030855 322 0.011
chromosome organization GO:0051276 360 0.011
axis specification GO:0009798 167 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
innate immune response GO:0045087 144 0.011
open tracheal system development GO:0007424 204 0.011
protein modification by small protein removal GO:0070646 28 0.011
single organism biosynthetic process GO:0044711 206 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
mrna metabolic process GO:0016071 124 0.010
central nervous system development GO:0007417 201 0.010
Fly
meiotic cell cycle GO:0051321 171 0.010
neurological system process GO:0050877 358 0.010
detection of stimulus GO:0051606 156 0.010
dendrite morphogenesis GO:0048813 199 0.010
cell migration GO:0016477 238 0.010
sterol homeostasis GO:0055092 4 0.010
cell division GO:0051301 248 0.010
salivary gland morphogenesis GO:0007435 145 0.010
regulation of protein kinase activity GO:0045859 51 0.010
regulation of kinase activity GO:0043549 53 0.010
growth GO:0040007 359 0.010
Fly
small gtpase mediated signal transduction GO:0007264 88 0.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.010
regulation of cysteine type endopeptidase activity GO:2000116 27 0.010
ras protein signal transduction GO:0007265 88 0.010
positive regulation of endopeptidase activity GO:0010950 26 0.010
chromosome segregation GO:0007059 157 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
regionalization GO:0003002 416 0.010
peptidyl tyrosine phosphorylation GO:0018108 24 0.010

sip3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
nervous system disease DOID:863 0 0.015
eye disease DOID:5614 0 0.015
disease of metabolism DOID:0014667 0 0.011