Drosophila melanogaster

26 known processes

Thd1 (Dmel_CG1981)

CG1981 gene product from transcript CG1981-RA

(Aliases: G/T-mismatch-specific-thymine-DNA-glycosylase,CG1981,Dmel\CG1981,1981)

Thd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic appendage morphogenesis GO:0035120 385 0.224
appendage development GO:0048736 401 0.211
imaginal disc derived appendage morphogenesis GO:0035114 395 0.196
epithelial cell differentiation GO:0030855 322 0.160
cell migration GO:0016477 238 0.137
appendage morphogenesis GO:0035107 397 0.118
response to organic substance GO:0010033 284 0.116
imaginal disc derived appendage development GO:0048737 399 0.113
negative regulation of cellular biosynthetic process GO:0031327 277 0.107
negative regulation of transcription dna templated GO:0045892 237 0.099
taxis GO:0042330 304 0.097
intracellular signal transduction GO:0035556 300 0.093
positive regulation of response to stimulus GO:0048584 323 0.090
wing disc morphogenesis GO:0007472 344 0.090
positive regulation of signal transduction GO:0009967 223 0.087
imaginal disc derived wing morphogenesis GO:0007476 337 0.085
regulation of anatomical structure morphogenesis GO:0022603 242 0.085
regulation of gene expression epigenetic GO:0040029 128 0.084
regulation of cell cycle process GO:0010564 181 0.084
axon development GO:0061564 297 0.082
gene silencing GO:0016458 138 0.080
epithelial cell development GO:0002064 274 0.078
positive regulation of signaling GO:0023056 243 0.076
chromatin silencing GO:0006342 76 0.074
organic substance transport GO:0071702 257 0.074
vesicle mediated transport GO:0016192 381 0.074
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.073
nucleoside metabolic process GO:0009116 127 0.072
regulation of phosphorylation GO:0042325 147 0.069
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.069
positive regulation of macromolecule metabolic process GO:0010604 405 0.066
response to wounding GO:0009611 94 0.065
regulation of response to stress GO:0080134 200 0.065
endocytosis GO:0006897 310 0.065
hindbrain development GO:0030902 2 0.064
negative regulation of cell communication GO:0010648 223 0.061
central nervous system development GO:0007417 201 0.060
negative regulation of gene expression epigenetic GO:0045814 77 0.059
response to nitrogen compound GO:1901698 90 0.058
response to oxygen containing compound GO:1901700 200 0.058
nucleotide metabolic process GO:0009117 161 0.057
ovarian follicle cell development GO:0030707 248 0.057
cell motility GO:0048870 251 0.057
nucleobase containing compound catabolic process GO:0034655 165 0.056
sensory organ morphogenesis GO:0090596 260 0.055
regulation of localization GO:0032879 275 0.054
organonitrogen compound metabolic process GO:1901564 318 0.054
body morphogenesis GO:0010171 2 0.053
response to endogenous stimulus GO:0009719 119 0.053
positive regulation of cell communication GO:0010647 250 0.053
negative regulation of response to stimulus GO:0048585 258 0.053
secretion by cell GO:0032940 101 0.052
carbohydrate derivative metabolic process GO:1901135 217 0.052
positive regulation of cellular component organization GO:0051130 156 0.051
glycosyl compound catabolic process GO:1901658 112 0.051
compound eye development GO:0048749 307 0.050
digestive system development GO:0055123 149 0.049
mitotic spindle organization GO:0007052 220 0.049
negative regulation of signaling GO:0023057 219 0.049
negative regulation of biosynthetic process GO:0009890 277 0.048
organic cyclic compound catabolic process GO:1901361 168 0.048
immune system process GO:0002376 347 0.048
negative regulation of signal transduction GO:0009968 206 0.048
cellular response to oxygen containing compound GO:1901701 79 0.046
regulation of phosphorus metabolic process GO:0051174 210 0.046
aromatic compound catabolic process GO:0019439 166 0.045
urogenital system development GO:0001655 72 0.045
cellular response to chemical stimulus GO:0070887 199 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.044
localization of cell GO:0051674 257 0.044
endomembrane system organization GO:0010256 119 0.044
nucleotide catabolic process GO:0009166 109 0.044
purine nucleotide catabolic process GO:0006195 109 0.043
ribonucleoside metabolic process GO:0009119 127 0.043
regulation of intracellular signal transduction GO:1902531 236 0.043
purine ribonucleotide catabolic process GO:0009154 109 0.042
ribonucleoside catabolic process GO:0042454 112 0.042
eye development GO:0001654 323 0.042
axon guidance GO:0007411 233 0.042
ameboidal type cell migration GO:0001667 151 0.042
positive regulation of cell migration GO:0030335 2 0.041
catabolic process GO:0009056 409 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.041
cellular response to organic substance GO:0071310 132 0.041
cilium assembly GO:0042384 38 0.040
positive regulation of phosphate metabolic process GO:0045937 139 0.040
phosphorylation GO:0016310 294 0.040
ras protein signal transduction GO:0007265 88 0.040
negative regulation of gene expression GO:0010629 387 0.039
compound eye morphogenesis GO:0001745 249 0.039
telencephalon development GO:0021537 2 0.039
negative regulation of developmental process GO:0051093 201 0.039
nucleoside phosphate metabolic process GO:0006753 162 0.038
regulation of multicellular organismal development GO:2000026 414 0.038
cellular catabolic process GO:0044248 372 0.038
cellular protein modification process GO:0006464 438 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
embryo development ending in birth or egg hatching GO:0009792 152 0.038
positive regulation of catabolic process GO:0009896 105 0.038
regulation of molecular function GO:0065009 217 0.038
regulation of catabolic process GO:0009894 170 0.037
ribonucleotide metabolic process GO:0009259 145 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
cellular response to endogenous stimulus GO:0071495 80 0.037
organic substance catabolic process GO:1901575 308 0.037
homeostatic process GO:0042592 199 0.037
cellular response to nitrogen compound GO:1901699 51 0.036
purine ribonucleoside catabolic process GO:0046130 112 0.036
neuron projection guidance GO:0097485 241 0.036
regulation of cellular catabolic process GO:0031329 157 0.036
negative regulation of nucleic acid templated transcription GO:1903507 240 0.036
negative regulation of cell differentiation GO:0045596 143 0.036
nucleoside triphosphate metabolic process GO:0009141 120 0.036
neurological system process GO:0050877 358 0.036
purine ribonucleoside metabolic process GO:0046128 127 0.036
cellular nitrogen compound catabolic process GO:0044270 165 0.036
cilium organization GO:0044782 41 0.035
positive regulation of intracellular signal transduction GO:1902533 116 0.035
establishment of localization in cell GO:0051649 402 0.035
regulation of organelle organization GO:0033043 196 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.035
compound eye photoreceptor cell differentiation GO:0001751 140 0.035
regulation of cell cycle GO:0051726 291 0.035
purine nucleotide metabolic process GO:0006163 146 0.035
gtp catabolic process GO:0006184 72 0.035
camera type eye development GO:0043010 4 0.035
single organism catabolic process GO:0044712 228 0.034
signal transduction by phosphorylation GO:0023014 107 0.034
protein localization GO:0008104 284 0.034
purine nucleoside metabolic process GO:0042278 127 0.034
ribonucleotide catabolic process GO:0009261 109 0.033
regulation of cellular ketone metabolic process GO:0010565 3 0.033
immune response GO:0006955 246 0.033
adult locomotory behavior GO:0008344 76 0.033
columnar cuboidal epithelial cell development GO:0002066 249 0.032
signal release GO:0023061 49 0.032
response to organonitrogen compound GO:0010243 75 0.032
phagocytosis GO:0006909 215 0.032
heterocycle catabolic process GO:0046700 166 0.032
small molecule metabolic process GO:0044281 305 0.032
regulation of mapk cascade GO:0043408 92 0.032
regulation of protein metabolic process GO:0051246 256 0.032
positive regulation of molecular function GO:0044093 136 0.032
embryonic morphogenesis GO:0048598 206 0.031
tissue morphogenesis GO:0048729 297 0.031
response to monosaccharide GO:0034284 4 0.031
regulation of phosphate metabolic process GO:0019220 210 0.031
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.031
organonitrogen compound catabolic process GO:1901565 128 0.031
purine containing compound metabolic process GO:0072521 155 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
protein transport GO:0015031 155 0.031
positive regulation of catalytic activity GO:0043085 118 0.030
regionalization GO:0003002 416 0.030
stem cell differentiation GO:0048863 117 0.030
single organism behavior GO:0044708 391 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.030
macromolecular complex assembly GO:0065003 256 0.029
secretion GO:0046903 109 0.029
regulation of cell development GO:0060284 215 0.029
muscle structure development GO:0061061 224 0.029
digestive tract morphogenesis GO:0048546 127 0.029
negative regulation of multicellular organismal process GO:0051241 142 0.029
photoreceptor cell differentiation GO:0046530 170 0.029
organelle assembly GO:0070925 198 0.029
negative regulation of rna biosynthetic process GO:1902679 240 0.029
developmental growth GO:0048589 280 0.028
cell division GO:0051301 248 0.028
neural precursor cell proliferation GO:0061351 75 0.028
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.027
chemotaxis GO:0006935 249 0.027
embryonic development via the syncytial blastoderm GO:0001700 148 0.027
organophosphate catabolic process GO:0046434 112 0.027
negative regulation of rna metabolic process GO:0051253 251 0.027
regulation of immune system process GO:0002682 176 0.027
cell projection assembly GO:0030031 94 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.027
positive regulation of cell motility GO:2000147 3 0.027
regulation of transport GO:0051049 181 0.027
regulation of nucleoside metabolic process GO:0009118 50 0.027
gland development GO:0048732 191 0.026
positive regulation of rna metabolic process GO:0051254 271 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.026
protein phosphorylation GO:0006468 169 0.026
purine containing compound catabolic process GO:0072523 112 0.026
response to biotic stimulus GO:0009607 294 0.026
cilium morphogenesis GO:0060271 39 0.026
negative regulation of intracellular signal transduction GO:1902532 57 0.026
eye morphogenesis GO:0048592 260 0.026
protein complex biogenesis GO:0070271 201 0.025
protein modification process GO:0036211 438 0.025
mapk cascade GO:0000165 107 0.025
nucleoside catabolic process GO:0009164 112 0.025
positive regulation of biosynthetic process GO:0009891 316 0.024
kidney development GO:0001822 3 0.024
purine nucleoside triphosphate metabolic process GO:0009144 119 0.024
growth GO:0040007 359 0.024
regulation of chromatin silencing GO:0031935 36 0.023
mitotic cell cycle phase transition GO:0044772 138 0.023
regulation of gene silencing GO:0060968 63 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
response to glucose GO:0009749 2 0.023
cellular protein localization GO:0034613 160 0.023
heart process GO:0003015 37 0.023
response to external biotic stimulus GO:0043207 293 0.023
cuticle development GO:0042335 86 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
regulation of nervous system development GO:0051960 248 0.023
spindle organization GO:0007051 253 0.023
jnk cascade GO:0007254 50 0.023
cell death GO:0008219 279 0.023
positive regulation of cellular component biogenesis GO:0044089 80 0.023
purine nucleoside catabolic process GO:0006152 112 0.023
intracellular transport GO:0046907 228 0.023
regulation of protein modification process GO:0031399 112 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
cell growth GO:0016049 108 0.022
regulation of cellular localization GO:0060341 136 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
regulation of catalytic activity GO:0050790 185 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
biological adhesion GO:0022610 138 0.022
nucleoside phosphate catabolic process GO:1901292 110 0.022
regulation of nucleotide catabolic process GO:0030811 48 0.022
positive regulation of nucleoside metabolic process GO:0045979 47 0.022
developmental maturation GO:0021700 172 0.021
regulation of cellular response to stress GO:0080135 89 0.021
brain development GO:0007420 120 0.021
stress activated mapk cascade GO:0051403 52 0.021
spinal cord development GO:0021510 1 0.021
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
glycosyl compound metabolic process GO:1901657 127 0.021
regulation of hydrolase activity GO:0051336 97 0.021
guanosine containing compound catabolic process GO:1901069 74 0.021
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
tube morphogenesis GO:0035239 191 0.021
gastrulation GO:0007369 70 0.020
eye photoreceptor cell differentiation GO:0001754 145 0.020
regulation of apoptotic process GO:0042981 130 0.020
regulation of programmed cell death GO:0043067 152 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
cell proliferation GO:0008283 299 0.020
meiotic cell cycle GO:0051321 171 0.020
regulation of gtpase activity GO:0043087 44 0.020
negative regulation of cell proliferation GO:0008285 69 0.020
axonogenesis GO:0007409 290 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
neuron recognition GO:0008038 101 0.019
regulation of membrane potential GO:0042391 35 0.019
response to abiotic stimulus GO:0009628 341 0.019
autophagy GO:0006914 108 0.019
cellular response to insulin stimulus GO:0032869 28 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
cell cycle phase transition GO:0044770 140 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
nucleoside triphosphate catabolic process GO:0009143 108 0.019
forebrain development GO:0030900 2 0.019
regulation of jnk cascade GO:0046328 40 0.019
cognition GO:0050890 141 0.019
programmed cell death GO:0012501 257 0.019
response to radiation GO:0009314 155 0.018
anatomical structure homeostasis GO:0060249 97 0.018
response to hexose GO:0009746 3 0.018
establishment of protein localization GO:0045184 163 0.018
anterior posterior pattern specification GO:0009952 136 0.018
chromosome organization GO:0051276 360 0.018
establishment of protein localization to organelle GO:0072594 62 0.018
cell fate determination GO:0001709 91 0.018
oxoacid metabolic process GO:0043436 103 0.018
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
positive regulation of nucleotide metabolic process GO:0045981 55 0.018
protein complex assembly GO:0006461 200 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
positive regulation of mapk cascade GO:0043410 63 0.017
regulation of developmental growth GO:0048638 174 0.017
innate immune response GO:0045087 144 0.017
negative regulation of cell development GO:0010721 62 0.017
regulation of cell proliferation GO:0042127 163 0.017
organelle fission GO:0048285 340 0.017
adult behavior GO:0030534 137 0.017
pigmentation GO:0043473 75 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
nuclear division GO:0000280 332 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
translation GO:0006412 69 0.017
locomotory behavior GO:0007626 176 0.017
regulation of locomotion GO:0040012 42 0.017
death GO:0016265 284 0.016
head development GO:0060322 135 0.016
gland morphogenesis GO:0022612 145 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
renal system development GO:0072001 72 0.016
positive regulation of hydrolase activity GO:0051345 78 0.016
tube development GO:0035295 244 0.016
regulation of multi organism process GO:0043900 131 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
positive regulation of growth GO:0045927 75 0.015
response to other organism GO:0051707 293 0.015
regulation of immune response GO:0050776 118 0.015
positive regulation of gtpase activity GO:0043547 43 0.015
regulation of cell migration GO:0030334 22 0.015
response to organic cyclic compound GO:0014070 89 0.015
positive regulation of nucleotide catabolic process GO:0030813 46 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.015
regulation of stress activated mapk cascade GO:0032872 41 0.015
cell adhesion GO:0007155 136 0.015
circulatory system process GO:0003013 37 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
regulation of actin cytoskeleton organization GO:0032956 42 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
tripartite regional subdivision GO:0007351 103 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
defense response GO:0006952 300 0.014
actin filament based process GO:0030029 220 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
response to reactive oxygen species GO:0000302 24 0.014
mitotic cytokinesis GO:0000281 50 0.014
leg disc development GO:0035218 92 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.014
cellular macromolecule localization GO:0070727 220 0.014
regulation of gtp catabolic process GO:0033124 44 0.014
cell recognition GO:0008037 102 0.014
chromosome segregation GO:0007059 157 0.014
single organism intracellular transport GO:1902582 207 0.014
intracellular protein transport GO:0006886 104 0.014
positive regulation of gene expression GO:0010628 290 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
response to lipopolysaccharide GO:0032496 4 0.013
regulation of secretion by cell GO:1903530 39 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
organic acid metabolic process GO:0006082 103 0.013
actin cytoskeleton organization GO:0030036 206 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
wnt signaling pathway GO:0016055 98 0.013
macromolecule catabolic process GO:0009057 161 0.013
axis specification GO:0009798 167 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
regulation of cell motility GO:2000145 23 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
regulation of cell differentiation GO:0045595 302 0.013
stress activated protein kinase signaling cascade GO:0031098 55 0.013
photoreceptor cell development GO:0042461 96 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
cell maturation GO:0048469 144 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.012
gtp metabolic process GO:0046039 72 0.012
regulation of embryonic development GO:0045995 68 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
mrna metabolic process GO:0016071 124 0.012
mrna processing GO:0006397 104 0.012
membrane organization GO:0061024 112 0.012
immune response activating signal transduction GO:0002757 2 0.012
positive regulation of developmental process GO:0051094 143 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
digestive tract development GO:0048565 149 0.012
regulation of organ morphogenesis GO:2000027 78 0.012
sex differentiation GO:0007548 81 0.012
cell cell junction organization GO:0045216 55 0.012
dephosphorylation GO:0016311 51 0.012
organelle localization GO:0051640 148 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
reproductive system development GO:0061458 74 0.012
negative regulation of organelle organization GO:0010639 56 0.011
synaptic transmission GO:0007268 288 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
learning or memory GO:0007611 141 0.011
cellular ketone metabolic process GO:0042180 24 0.011
response to bacterium GO:0009617 198 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
positive regulation of cell death GO:0010942 69 0.011
epithelium migration GO:0090132 148 0.011
rho protein signal transduction GO:0007266 14 0.011
regulation of neuron differentiation GO:0045664 103 0.011
cellular homeostasis GO:0019725 80 0.011
skin development GO:0043588 65 0.011
apoptotic process GO:0006915 159 0.011
spermatogenesis GO:0007283 200 0.011
heart development GO:0007507 82 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
regulation of cell death GO:0010941 173 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
organophosphate metabolic process GO:0019637 195 0.011
regulation of protein kinase activity GO:0045859 51 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
muscle organ development GO:0007517 127 0.010
cellular response to organonitrogen compound GO:0071417 36 0.010
regulation of neurogenesis GO:0050767 158 0.010
neuroblast proliferation GO:0007405 74 0.010
compound eye retinal cell programmed cell death GO:0046667 23 0.010
response to hormone GO:0009725 45 0.010
asymmetric protein localization GO:0008105 33 0.010
multi organism behavior GO:0051705 175 0.010
epithelial cell migration GO:0010631 148 0.010
cytokinesis GO:0000910 90 0.010
regulation of protein transport GO:0051223 57 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.010
mitotic nuclear division GO:0007067 213 0.010

Thd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.013