Drosophila melanogaster

0 known processes

Cyp4e1 (Dmel_CG2062)

Cytochrome P450-4e1

(Aliases: P-450,CG2062,Dmel\CG2062,4e1,CYP4E1,P450)

Cyp4e1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
steroid catabolic process GO:0006706 1 0.106
anion homeostasis GO:0055081 3 0.090
fat soluble vitamin metabolic process GO:0006775 1 0.080
hormone catabolic process GO:0042447 3 0.068
vesicle mediated transport GO:0016192 381 0.063
catabolic process GO:0009056 409 0.062
insecticide metabolic process GO:0017143 2 0.057
xenobiotic catabolic process GO:0042178 1 0.056
oxoacid metabolic process GO:0043436 103 0.055
response to abiotic stimulus GO:0009628 341 0.054
endocytosis GO:0006897 310 0.053
lateral inhibition GO:0046331 206 0.050
defense response GO:0006952 300 0.050
organic substance catabolic process GO:1901575 308 0.047
response to other organism GO:0051707 293 0.047
cellular catabolic process GO:0044248 372 0.047
single organism catabolic process GO:0044712 228 0.047
response to external biotic stimulus GO:0043207 293 0.046
response to biotic stimulus GO:0009607 294 0.045
lipid metabolic process GO:0006629 121 0.045
cell cell signaling involved in cell fate commitment GO:0045168 210 0.044
sensory perception of chemical stimulus GO:0007606 116 0.043
response to bacterium GO:0009617 198 0.043
small molecule metabolic process GO:0044281 305 0.042
single organism behavior GO:0044708 391 0.038
phagocytosis GO:0006909 215 0.038
medium chain fatty acid metabolic process GO:0051791 1 0.038
neurological system process GO:0050877 358 0.037
carboxylic acid metabolic process GO:0019752 92 0.037
vitamin biosynthetic process GO:0009110 1 0.037
response to organic substance GO:0010033 284 0.036
organic substance transport GO:0071702 257 0.035
response to lipopolysaccharide GO:0032496 4 0.035
androgen metabolic process GO:0008209 1 0.035
toxin metabolic process GO:0009404 2 0.034
l amino acid import GO:0043092 2 0.034
defense response to bacterium GO:0042742 178 0.034
cellular ketone metabolic process GO:0042180 24 0.034
cellular protein modification process GO:0006464 438 0.033
organic cyclic compound catabolic process GO:1901361 168 0.032
protein modification process GO:0036211 438 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
regulation of multicellular organismal development GO:2000026 414 0.031
sensory perception GO:0007600 196 0.031
vitamin metabolic process GO:0006766 2 0.030
lauric acid metabolic process GO:0048252 1 0.030
immune response GO:0006955 246 0.030
response to mercury ion GO:0046689 3 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
response to nutrient levels GO:0031667 114 0.028
developmental growth GO:0048589 280 0.028
response to oxygen containing compound GO:1901700 200 0.028
regulation of localization GO:0032879 275 0.028
gland development GO:0048732 191 0.028
sensory perception of smell GO:0007608 80 0.028
single organism biosynthetic process GO:0044711 206 0.027
defense response to other organism GO:0098542 225 0.027
organonitrogen compound metabolic process GO:1901564 318 0.026
fat soluble vitamin biosynthetic process GO:0042362 1 0.026
growth GO:0040007 359 0.026
body morphogenesis GO:0010171 2 0.026
toxin catabolic process GO:0009407 1 0.026
cellular nitrogen compound catabolic process GO:0044270 165 0.026
response to organophosphorus GO:0046683 2 0.025
taxis GO:0042330 304 0.025
aromatic compound catabolic process GO:0019439 166 0.025
regulation of developmental growth GO:0048638 174 0.025
immune system process GO:0002376 347 0.025
positive regulation of gene expression GO:0010628 290 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
post embryonic appendage morphogenesis GO:0035120 385 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
positive regulation of cell communication GO:0010647 250 0.023
organic acid metabolic process GO:0006082 103 0.023
benzene containing compound metabolic process GO:0042537 3 0.023
detection of stimulus GO:0051606 156 0.023
cellular hormone metabolic process GO:0034754 23 0.023
nuclear division GO:0000280 332 0.022
salivary gland morphogenesis GO:0007435 145 0.022
kidney development GO:0001822 3 0.022
phosphate ion transport GO:0006817 4 0.022
cellular amino acid metabolic process GO:0006520 61 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
regulation of cell cycle GO:0051726 291 0.022
cellular response to ethanol GO:0071361 4 0.022
response to temperature stimulus GO:0009266 106 0.022
acylglycerol catabolic process GO:0046464 3 0.021
chaeta development GO:0022416 97 0.021
death GO:0016265 284 0.021
appendage morphogenesis GO:0035107 397 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
appendage development GO:0048736 401 0.021
organelle fission GO:0048285 340 0.021
heterocycle catabolic process GO:0046700 166 0.021
salivary gland development GO:0007431 162 0.020
cell death GO:0008219 279 0.020
regulation of catalytic activity GO:0050790 185 0.020
regulation of transport GO:0051049 181 0.020
positive regulation of multicellular organismal process GO:0051240 143 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
cell proliferation GO:0008283 299 0.020
regionalization GO:0003002 416 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
regulation of molecular function GO:0065009 217 0.020
establishment of localization in cell GO:0051649 402 0.020
polyol biosynthetic process GO:0046173 3 0.020
intracellular signal transduction GO:0035556 300 0.020
secondary metabolite catabolic process GO:0090487 1 0.020
cellular amine metabolic process GO:0044106 12 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
wing disc morphogenesis GO:0007472 344 0.020
exocrine system development GO:0035272 162 0.019
response to radiation GO:0009314 155 0.019
positive regulation of signaling GO:0023056 243 0.019
negative regulation of gene expression GO:0010629 387 0.019
homeostatic process GO:0042592 199 0.019
sterol homeostasis GO:0055092 4 0.019
response to endogenous stimulus GO:0009719 119 0.019
gland morphogenesis GO:0022612 145 0.019
positive regulation of signal transduction GO:0009967 223 0.019
multi organism behavior GO:0051705 175 0.019
multicellular organismal aging GO:0010259 140 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
cellular response to organic substance GO:0071310 132 0.018
regulation of anatomical structure size GO:0090066 163 0.018
positive regulation of lipid storage GO:0010884 4 0.018
phosphorylation GO:0016310 294 0.018
cellular response to radiation GO:0071478 52 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
proteolysis GO:0006508 192 0.018
camera type eye development GO:0043010 4 0.018
connective tissue development GO:0061448 3 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
organophosphate metabolic process GO:0019637 195 0.017
positive regulation of cell migration GO:0030335 2 0.017
regulation of response to stress GO:0080134 200 0.017
macromolecular complex assembly GO:0065003 256 0.017
aging GO:0007568 143 0.017
response to extracellular stimulus GO:0009991 116 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
negative regulation of cell communication GO:0010648 223 0.017
response to nitrogen compound GO:1901698 90 0.017
response to glucose GO:0009749 2 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
intracellular transport GO:0046907 228 0.016
l glutamate import GO:0051938 1 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
innate immune response GO:0045087 144 0.016
insecticide catabolic process GO:0046701 1 0.016
transmembrane transport GO:0055085 139 0.016
programmed cell death GO:0012501 257 0.016
response to hexose GO:0009746 3 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
cell motility GO:0048870 251 0.016
compound eye development GO:0048749 307 0.016
amine metabolic process GO:0009308 12 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
forebrain development GO:0030900 2 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
rna processing GO:0006396 147 0.016
protein localization GO:0008104 284 0.016
positive regulation of molecular function GO:0044093 136 0.016
single organism intracellular transport GO:1902582 207 0.016
response to monosaccharide GO:0034284 4 0.016
cellular macromolecule localization GO:0070727 220 0.016
estrogen metabolic process GO:0008210 1 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
cholesterol transport GO:0030301 2 0.016
positive regulation of cell motility GO:2000147 3 0.016
pigmentation GO:0043473 75 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.015
spindle organization GO:0007051 253 0.015
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
localization of cell GO:0051674 257 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
regulation of protein metabolic process GO:0051246 256 0.015
macromolecule catabolic process GO:0009057 161 0.015
regulation of growth GO:0040008 233 0.015
rhythmic process GO:0048511 106 0.015
cellular response to abiotic stimulus GO:0071214 58 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
steroid metabolic process GO:0008202 20 0.015
negative regulation of signaling GO:0023057 219 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
chemotaxis GO:0006935 249 0.015
protein phosphorylation GO:0006468 169 0.014
cellular lipid metabolic process GO:0044255 83 0.014
regulation of cell differentiation GO:0045595 302 0.014
regulation of cell death GO:0010941 173 0.014
organelle assembly GO:0070925 198 0.014
regulation of catabolic process GO:0009894 170 0.014
regulation of hormone levels GO:0010817 40 0.014
nucleotide catabolic process GO:0009166 109 0.014
organophosphate catabolic process GO:0046434 112 0.014
triglyceride catabolic process GO:0019433 3 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
negative regulation of signal transduction GO:0009968 206 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
open tracheal system development GO:0007424 204 0.014
pigment biosynthetic process GO:0046148 36 0.014
nucleotide metabolic process GO:0009117 161 0.014
protein complex biogenesis GO:0070271 201 0.014
ethanolamine containing compound metabolic process GO:0042439 4 0.014
developmental pigmentation GO:0048066 68 0.014
very long chain fatty acid metabolic process GO:0000038 4 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
tissue morphogenesis GO:0048729 297 0.014
respiratory system development GO:0060541 213 0.014
inter male aggressive behavior GO:0002121 60 0.014
phosphatidylethanolamine metabolic process GO:0046337 1 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
neutral lipid biosynthetic process GO:0046460 2 0.014
carbohydrate metabolic process GO:0005975 82 0.013
segmentation GO:0035282 207 0.013
steroid biosynthetic process GO:0006694 16 0.013
endomembrane system organization GO:0010256 119 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
regulation of cell proliferation GO:0042127 163 0.013
axis specification GO:0009798 167 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
cellular homeostasis GO:0019725 80 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
mating GO:0007618 120 0.013
protein transport GO:0015031 155 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
immune response activating signal transduction GO:0002757 2 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
cell cycle phase transition GO:0044770 140 0.013
epithelial cell development GO:0002064 274 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
ras protein signal transduction GO:0007265 88 0.013
regulation of immune system process GO:0002682 176 0.013
maintenance of location GO:0051235 73 0.013
aggressive behavior GO:0002118 63 0.013
sodium dependent phosphate transport GO:0044341 2 0.013
response to starvation GO:0042594 97 0.013
nitrogen compound transport GO:0071705 85 0.013
cell migration GO:0016477 238 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
cellularization GO:0007349 90 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
humoral immune response GO:0006959 117 0.012
regulation of lipid transport GO:0032368 3 0.012
nucleoside catabolic process GO:0009164 112 0.012
triglyceride biosynthetic process GO:0019432 2 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
compound eye morphogenesis GO:0001745 249 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
autophagic cell death GO:0048102 83 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
cell division GO:0051301 248 0.012
response to organic cyclic compound GO:0014070 89 0.012
antimicrobial humoral response GO:0019730 99 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
biological adhesion GO:0022610 138 0.012
ion transport GO:0006811 145 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
monocarboxylic acid transport GO:0015718 3 0.012
regulation of sequestering of triglyceride GO:0010889 3 0.012
neuron projection guidance GO:0097485 241 0.012
cholesterol homeostasis GO:0042632 3 0.012
telencephalon development GO:0021537 2 0.012
response to alcohol GO:0097305 95 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
axon guidance GO:0007411 233 0.012
negative regulation of developmental process GO:0051093 201 0.012
eye development GO:0001654 323 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
regulation of multi organism process GO:0043900 131 0.012
eye morphogenesis GO:0048592 260 0.012
cell adhesion GO:0007155 136 0.012
purine containing compound catabolic process GO:0072523 112 0.012
secondary metabolic process GO:0019748 75 0.012
central nervous system development GO:0007417 201 0.012
developmental maturation GO:0021700 172 0.012
developmental programmed cell death GO:0010623 138 0.012
cuticle development GO:0042335 86 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
actin filament based process GO:0030029 220 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
tissue death GO:0016271 102 0.012
cytoplasmic transport GO:0016482 130 0.012
regulation of apoptotic process GO:0042981 130 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
glycerolipid catabolic process GO:0046503 3 0.012
cation transport GO:0006812 110 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
neutral lipid catabolic process GO:0046461 3 0.011
histolysis GO:0007559 102 0.011
nucleoside metabolic process GO:0009116 127 0.011
regulation of cell development GO:0060284 215 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
pigment metabolic process involved in pigmentation GO:0043474 33 0.011
establishment of protein localization GO:0045184 163 0.011
ion transmembrane transport GO:0034220 122 0.011
male gamete generation GO:0048232 201 0.011
regulation of response to external stimulus GO:0032101 115 0.011
regulation of immune response GO:0050776 118 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
positive regulation of catabolic process GO:0009896 105 0.011
chromosome organization GO:0051276 360 0.011
protein complex assembly GO:0006461 200 0.011
synaptic transmission GO:0007268 288 0.011
salivary gland histolysis GO:0035070 88 0.011
oligosaccharide transport GO:0015772 2 0.011
purine containing compound metabolic process GO:0072521 155 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
small molecule biosynthetic process GO:0044283 37 0.011
regulation of nervous system development GO:0051960 248 0.011
synapse assembly GO:0007416 143 0.011
determination of adult lifespan GO:0008340 137 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
mitotic nuclear division GO:0007067 213 0.011
courtship behavior GO:0007619 68 0.011
embryonic pattern specification GO:0009880 174 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
tube development GO:0035295 244 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
alditol phosphate metabolic process GO:0052646 2 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
synapse organization GO:0050808 196 0.011
response to copper ion GO:0046688 4 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
response to ethanol GO:0045471 59 0.011
single organism cellular localization GO:1902580 180 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
regulation of programmed cell death GO:0043067 152 0.011
cell recognition GO:0008037 102 0.011
drinking behavior GO:0042756 2 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
gene silencing GO:0016458 138 0.011
secretion GO:0046903 109 0.011
regulation of phosphorylation GO:0042325 147 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
locomotory behavior GO:0007626 176 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
regulation of hydrolase activity GO:0051336 97 0.010
axon development GO:0061564 297 0.010
sensory organ morphogenesis GO:0090596 260 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
sensory perception of pain GO:0019233 4 0.010
hormone metabolic process GO:0042445 33 0.010
anterior posterior pattern specification GO:0009952 136 0.010
response to organonitrogen compound GO:0010243 75 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010
cellular response to dna damage stimulus GO:0006974 223 0.010
hindbrain development GO:0030902 2 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
organic hydroxy compound metabolic process GO:1901615 83 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
tube morphogenesis GO:0035239 191 0.010
phosphatidic acid metabolic process GO:0046473 1 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
negative regulation of rna biosynthetic process GO:1902679 240 0.010
peptidyl amino acid modification GO:0018193 105 0.010
spermatogenesis GO:0007283 200 0.010
response to light stimulus GO:0009416 124 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
retina development in camera type eye GO:0060041 4 0.010
mesenchymal cell development GO:0014031 1 0.010
regulation of proteolysis GO:0030162 87 0.010
axonogenesis GO:0007409 290 0.010
detection of external stimulus GO:0009581 66 0.010
cation transmembrane transport GO:0098655 88 0.010
purine nucleoside catabolic process GO:0006152 112 0.010
response to lipid GO:0033993 38 0.010

Cyp4e1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
hypertension DOID:10763 0 0.027
artery disease DOID:0050828 0 0.027
vascular disease DOID:178 0 0.027
cardiovascular system disease DOID:1287 0 0.027
essential hypertension DOID:10825 0 0.021
disease of metabolism DOID:0014667 0 0.020
nervous system disease DOID:863 0 0.019
inherited metabolic disorder DOID:655 0 0.017
carbohydrate metabolism disease DOID:0050013 0 0.014
glucose metabolism disease DOID:4194 0 0.014
acquired metabolic disease DOID:0060158 0 0.014
diabetes mellitus DOID:9351 0 0.013
type 2 diabetes mellitus DOID:9352 0 0.013
musculoskeletal system disease DOID:17 0 0.012
renal tubular transport disease DOID:447 0 0.011
kidney disease DOID:557 0 0.011
urinary system disease DOID:18 0 0.011
sensory system disease DOID:0050155 0 0.010
familial hyperlipidemia DOID:1168 0 0.010
lipid metabolism disorder DOID:3146 0 0.010
familial combined hyperlipidemia DOID:13809 0 0.010