Drosophila melanogaster

191 known processes

ci (Dmel_CG2125)

cubitus interruptus

(Aliases: Gli,CI,Ci[D],Ci155,CID,l(4)102ABc,ci155,CiD,ci-D,Ci,Ce,l(4)17,ciD,ci[D],Ci/Gli,CG2125,Ci/GLI,l(4)13,Dmel\CG2125,Siah)

ci biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 378 1.000
regionalization GO:0003002 416 1.000
positive regulation of transcription dna templated GO:0045893 266 1.000
positive regulation of rna metabolic process GO:0051254 271 1.000
muscle structure development GO:0061061 224 0.999
Zebrafish Fly
negative regulation of developmental process GO:0051093 201 0.999
Mouse
renal system development GO:0072001 72 0.999
Zebrafish Mouse
respiratory system development GO:0060541 213 0.999
tube morphogenesis GO:0035239 191 0.999
Zebrafish Mouse
epithelial cell differentiation GO:0030855 322 0.999
nephron tubule morphogenesis GO:0072078 3 0.999
Mouse
nephron development GO:0072006 3 0.998
Zebrafish Mouse
central nervous system development GO:0007417 201 0.998
Zebrafish Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.998
positive regulation of rna biosynthetic process GO:1902680 266 0.998
negative regulation of nucleic acid templated transcription GO:1903507 240 0.998
Human Mouse Worm
tube development GO:0035295 244 0.998
Zebrafish Mouse
organ formation GO:0048645 39 0.998
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.998
regulation of epithelial cell proliferation GO:0050678 4 0.997
positive regulation of gene expression GO:0010628 290 0.997
cell death GO:0008219 279 0.996
Mouse Worm
negative regulation of cell differentiation GO:0045596 143 0.996
Mouse
nephron epithelium morphogenesis GO:0072088 3 0.996
Mouse
blastoderm segmentation GO:0007350 159 0.996
imaginal disc pattern formation GO:0007447 91 0.995
stem cell differentiation GO:0048863 117 0.995
positive regulation of biosynthetic process GO:0009891 316 0.995
nephron epithelium development GO:0072009 3 0.994
Mouse
nephron morphogenesis GO:0072028 3 0.994
Mouse
digestive system development GO:0055123 149 0.994
Zebrafish Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.994
morphogenesis of embryonic epithelium GO:0016331 94 0.994
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.993
post embryonic appendage morphogenesis GO:0035120 385 0.993
positive regulation of cell proliferation GO:0008284 47 0.992
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.992
Human Mouse Worm
digestive tract morphogenesis GO:0048546 127 0.992
Zebrafish Mouse
digestive tract development GO:0048565 149 0.992
Zebrafish Mouse
stem cell development GO:0048864 79 0.991
regulation of cell differentiation GO:0045595 302 0.991
open tracheal system development GO:0007424 204 0.991
heart morphogenesis GO:0003007 32 0.990
transcription from rna polymerase ii promoter GO:0006366 368 0.990
epithelial cell development GO:0002064 274 0.989
embryonic organ development GO:0048568 50 0.988
Zebrafish Mouse
muscle tissue development GO:0060537 30 0.988
Fly
negative regulation of transcription dna templated GO:0045892 237 0.988
Human Mouse Worm
urogenital system development GO:0001655 72 0.987
Zebrafish Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.986
Human Mouse Worm
wing disc pattern formation GO:0035222 66 0.985
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.984
Mouse
stem cell maintenance GO:0019827 67 0.983
embryonic morphogenesis GO:0048598 206 0.983
Zebrafish Mouse
kidney morphogenesis GO:0060993 3 0.982
Mouse
cardiovascular system development GO:0072358 82 0.982
negative regulation of programmed cell death GO:0043069 72 0.981
Mouse
epithelial tube formation GO:0072175 7 0.981
kidney epithelium development GO:0072073 3 0.980
Mouse
kidney development GO:0001822 3 0.979
Zebrafish Mouse
epithelial tube morphogenesis GO:0060562 88 0.978
Mouse
regulation of muscle organ development GO:0048634 13 0.978
programmed cell death GO:0012501 257 0.978
Mouse Worm
ovarian follicle cell development GO:0030707 248 0.977
dorsal ventral pattern formation GO:0009953 133 0.976
Zebrafish Mouse
neurological system process GO:0050877 358 0.975
regulation of phosphate metabolic process GO:0019220 210 0.975
negative regulation of biosynthetic process GO:0009890 277 0.974
Human Mouse Worm
death GO:0016265 284 0.971
Mouse Worm
forebrain development GO:0030900 2 0.967
Zebrafish Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.966
signal transduction downstream of smoothened GO:0007227 5 0.966
leg disc development GO:0035218 92 0.966
anterior posterior pattern specification GO:0009952 136 0.962
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.961
Human Mouse Worm
muscle organ development GO:0007517 127 0.961
Zebrafish Fly
stem cell proliferation GO:0072089 88 0.959
Mouse
camera type eye development GO:0043010 4 0.956
Mouse
dorsal closure GO:0007391 79 0.956
appendage morphogenesis GO:0035107 397 0.956
Human Mouse
apoptotic process involved in morphogenesis GO:0060561 3 0.955
eye morphogenesis GO:0048592 260 0.954
embryonic digestive tract morphogenesis GO:0048557 4 0.954
Zebrafish Mouse
smoothened signaling pathway GO:0007224 49 0.953
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.952
regulation of apoptotic process GO:0042981 130 0.951
Mouse Worm
eggshell chorion assembly GO:0007306 66 0.950
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.950
compound eye morphogenesis GO:0001745 249 0.949
sensory organ morphogenesis GO:0090596 260 0.945
positive regulation of macromolecule metabolic process GO:0010604 405 0.944
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.943
Human Mouse Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.943
Human Mouse Worm
glial cell differentiation GO:0010001 35 0.942
Mouse
tissue morphogenesis GO:0048729 297 0.941
Zebrafish Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.941
Human Mouse Worm
embryonic digestive tract development GO:0048566 5 0.940
Zebrafish Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.940
embryo development ending in birth or egg hatching GO:0009792 152 0.938
Zebrafish Mouse Worm
negative regulation of cell communication GO:0010648 223 0.938
Human Mouse
epithelial cell proliferation GO:0050673 15 0.937
imaginal disc derived leg morphogenesis GO:0007480 80 0.937
regulation of cell death GO:0010941 173 0.936
Mouse Worm
mesenchymal cell differentiation GO:0048762 1 0.935
cardiocyte differentiation GO:0035051 29 0.935
negative regulation of cell death GO:0060548 81 0.934
Mouse
regulation of cell proliferation GO:0042127 163 0.931
Human Mouse
apoptotic process GO:0006915 159 0.931
Mouse Worm
morphogenesis of an epithelium GO:0002009 276 0.929
Mouse
muscle cell development GO:0055001 50 0.928
Zebrafish
heart development GO:0007507 82 0.927
regulation of striated muscle tissue development GO:0016202 5 0.927
positive regulation of cellular biosynthetic process GO:0031328 316 0.926
response to organic substance GO:0010033 284 0.926
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.925
Human Mouse Worm
synapse organization GO:0050808 196 0.923
gland development GO:0048732 191 0.921
Zebrafish Mouse
growth GO:0040007 359 0.918
Mouse
phosphorylation GO:0016310 294 0.918
formation of primary germ layer GO:0001704 24 0.917
connective tissue development GO:0061448 3 0.912
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.912
germarium derived egg chamber formation GO:0007293 101 0.912
spinal cord dorsal ventral patterning GO:0021513 1 0.910
Zebrafish Mouse
eggshell formation GO:0030703 105 0.909
endocrine system development GO:0035270 5 0.907
Zebrafish Mouse
segmentation GO:0035282 207 0.906
negative regulation of signal transduction GO:0009968 206 0.903
Human Mouse
mesoderm development GO:0007498 78 0.901
dendrite development GO:0016358 204 0.896
regulation of programmed cell death GO:0043067 152 0.894
Mouse Worm
hindbrain development GO:0030902 2 0.893
Zebrafish Mouse
imaginal disc derived appendage development GO:0048737 399 0.891
circulatory system development GO:0072359 82 0.890
retinal ganglion cell axon guidance GO:0031290 12 0.890
Zebrafish
positive regulation of hh target transcription factor activity GO:0007228 5 0.889
imaginal disc derived wing morphogenesis GO:0007476 337 0.888
ameboidal type cell migration GO:0001667 151 0.888
immune system process GO:0002376 347 0.878
Mouse
anterior posterior pattern specification imaginal disc GO:0007448 16 0.878
hemopoiesis GO:0030097 46 0.876
Mouse
axis specification GO:0009798 167 0.874
regulation of organ formation GO:0003156 3 0.870
limb morphogenesis GO:0035108 1 0.869
Human Mouse
regulation of heart morphogenesis GO:2000826 3 0.869
male gamete generation GO:0048232 201 0.869
Mouse Worm
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.864
negative regulation of signaling GO:0023057 219 0.860
Human Mouse
developmental programmed cell death GO:0010623 138 0.859
skeletal muscle tissue development GO:0007519 13 0.857
Fly
bmp signaling pathway GO:0030509 27 0.857
renal tubule morphogenesis GO:0061333 44 0.856
Mouse
neuron projection guidance GO:0097485 241 0.856
Zebrafish Mouse
gastrulation GO:0007369 70 0.852
skeletal muscle organ development GO:0060538 48 0.851
Fly
striated muscle tissue development GO:0014706 27 0.850
Fly
ventral midline development GO:0007418 9 0.849
Zebrafish Mouse
response to external biotic stimulus GO:0043207 293 0.849
Human
eye development GO:0001654 323 0.846
extracellular structure organization GO:0043062 46 0.843
axon guidance GO:0007411 233 0.839
Zebrafish Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.837
Human Mouse Worm
salivary gland morphogenesis GO:0007435 145 0.836
wing disc morphogenesis GO:0007472 344 0.836
cellular macromolecule localization GO:0070727 220 0.836
Mouse
regulation of cell cycle GO:0051726 291 0.834
chromosome organization GO:0051276 360 0.834
gland morphogenesis GO:0022612 145 0.833
Zebrafish Mouse
eye antennal disc development GO:0035214 60 0.832
formation of anatomical boundary GO:0048859 37 0.831
renal tubule development GO:0061326 64 0.830
Mouse
negative regulation of response to stimulus GO:0048585 258 0.823
Human Mouse
regulation of growth GO:0040008 233 0.822
genital disc development GO:0035215 44 0.817
embryonic heart tube development GO:0035050 22 0.816
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.814
negative regulation of apoptotic process GO:0043066 63 0.808
Mouse
head development GO:0060322 135 0.807
Zebrafish Mouse
chorion containing eggshell formation GO:0007304 105 0.806
negative regulation of nervous system development GO:0051961 92 0.805
Mouse
response to nutrient levels GO:0031667 114 0.804
nephron tubule development GO:0072080 3 0.802
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.799
imaginal disc derived leg segmentation GO:0036011 26 0.797
negative regulation of wnt signaling pathway GO:0030178 28 0.796
Human
organic acid metabolic process GO:0006082 103 0.795
apoptotic process involved in development GO:1902742 20 0.795
cell fate specification GO:0001708 71 0.795
Zebrafish Mouse
protein localization GO:0008104 284 0.793
Mouse
anterior posterior axis specification GO:0009948 109 0.792
regulation of bmp signaling pathway GO:0030510 23 0.787
cellular response to organic substance GO:0071310 132 0.784
Mouse
negative regulation of gene expression GO:0010629 387 0.783
Human Mouse Worm
mesodermal cell fate specification GO:0007501 2 0.782
cellular component assembly involved in morphogenesis GO:0010927 151 0.780
negative regulation of cell development GO:0010721 62 0.777
Mouse
sensory perception GO:0007600 196 0.777
retina development in camera type eye GO:0060041 4 0.773
taxis GO:0042330 304 0.764
Zebrafish Mouse
sulfur compound metabolic process GO:0006790 59 0.761
intracellular transport GO:0046907 228 0.761
Mouse
regulation of stem cell differentiation GO:2000736 14 0.759
exocrine system development GO:0035272 162 0.751
embryonic organ morphogenesis GO:0048562 5 0.745
Zebrafish Mouse
cellular protein modification process GO:0006464 438 0.742
regulation of synapse structure and activity GO:0050803 128 0.739
compound eye development GO:0048749 307 0.732
regulation of anatomical structure morphogenesis GO:0022603 242 0.730
labial disc development GO:0035217 4 0.727
developmental growth GO:0048589 280 0.727
Mouse
epithelial cell migration GO:0010631 148 0.725
regulation of cell fate specification GO:0042659 27 0.724
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.724
cellular ketone metabolic process GO:0042180 24 0.722
cell fate determination GO:0001709 91 0.715
synapse assembly GO:0007416 143 0.714
spinal cord development GO:0021510 1 0.713
Zebrafish Mouse
telencephalon development GO:0021537 2 0.712
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.704
Mouse
larval development GO:0002164 104 0.701
epidermal cell differentiation GO:0009913 51 0.699
Human
appendage development GO:0048736 401 0.695
Human Mouse
muscle cell differentiation GO:0042692 103 0.695
Zebrafish Fly
oxoacid metabolic process GO:0043436 103 0.694
regulation of muscle tissue development GO:1901861 5 0.693
negative regulation of neurogenesis GO:0050768 53 0.692
Mouse
circadian rhythm GO:0007623 105 0.689
cell motility GO:0048870 251 0.688
Mouse Worm
negative regulation of rna biosynthetic process GO:1902679 240 0.688
Human Mouse Worm
malpighian tubule development GO:0072002 64 0.686
cell proliferation GO:0008283 299 0.682
Human Mouse
regulation of synapse organization GO:0050807 110 0.680
cardioblast differentiation GO:0010002 20 0.673
chemotaxis GO:0006935 249 0.670
Zebrafish Mouse
enteroendocrine cell differentiation GO:0035883 1 0.667
regulation of protein metabolic process GO:0051246 256 0.658
camera type eye morphogenesis GO:0048593 2 0.657
Mouse
segment polarity determination GO:0007367 25 0.655
embryonic epithelial tube formation GO:0001838 6 0.650
tube formation GO:0035148 21 0.645
regulation of wnt signaling pathway GO:0030111 68 0.643
Human
single organism biosynthetic process GO:0044711 206 0.643
regulation of mitotic cell cycle GO:0007346 190 0.638
regulation of cell fate commitment GO:0010453 29 0.633
aminoglycan metabolic process GO:0006022 18 0.631
response to abiotic stimulus GO:0009628 341 0.631
glial cell migration GO:0008347 31 0.628
protein targeting to nucleus GO:0044744 51 0.625
Mouse
positive regulation of signaling GO:0023056 243 0.625
Human Zebrafish
cellular response to endogenous stimulus GO:0071495 80 0.624
mesodermal cell differentiation GO:0048333 7 0.624
notch signaling pathway GO:0007219 120 0.612
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.609
macromolecule catabolic process GO:0009057 161 0.607
imaginal disc derived wing hair organization GO:0035317 45 0.606
embryonic development via the syncytial blastoderm GO:0001700 148 0.602
meiotic nuclear division GO:0007126 151 0.601
Worm
positive regulation of muscle organ development GO:0048636 6 0.599
malpighian tubule morphogenesis GO:0007443 44 0.599
genital disc pattern formation GO:0035221 8 0.595
vesicle mediated transport GO:0016192 381 0.593
Worm
specification of organ identity GO:0010092 3 0.591
Mouse
regulation of immune system process GO:0002682 176 0.591
Mouse
salivary gland development GO:0007431 162 0.589
regulation of reproductive process GO:2000241 54 0.585
mesoderm morphogenesis GO:0048332 22 0.582
regulation of developmental growth GO:0048638 174 0.576
gliogenesis GO:0042063 80 0.574
Mouse
negative regulation of cell cycle GO:0045786 116 0.570
protein localization to nucleus GO:0034504 55 0.559
Mouse
glial cell development GO:0021782 27 0.554
reproductive structure development GO:0048608 74 0.551
Mouse Worm
nucleocytoplasmic transport GO:0006913 72 0.550
Mouse
striated muscle cell differentiation GO:0051146 90 0.549
Zebrafish Fly
leg disc morphogenesis GO:0007478 80 0.539
cellular amino acid metabolic process GO:0006520 61 0.533
imaginal disc derived wing vein specification GO:0007474 48 0.532
endodermal cell fate commitment GO:0001711 3 0.531
myotube cell development GO:0014904 3 0.528
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.527
organelle localization GO:0051640 148 0.524
compound eye photoreceptor cell differentiation GO:0001751 140 0.520
negative regulation of immune system process GO:0002683 50 0.520
Mouse
eye photoreceptor cell differentiation GO:0001754 145 0.516
spinal cord patterning GO:0021511 1 0.516
Zebrafish Mouse
germ cell migration GO:0008354 43 0.506
endodermal cell differentiation GO:0035987 3 0.505
dna metabolic process GO:0006259 227 0.501
Human
cellular protein localization GO:0034613 160 0.499
Mouse
single organism cellular localization GO:1902580 180 0.498
Mouse
response to hormone GO:0009725 45 0.496
dendrite morphogenesis GO:0048813 199 0.495
mesoderm formation GO:0001707 21 0.489
homeostatic process GO:0042592 199 0.483
skeletal muscle fiber development GO:0048741 3 0.481
anatomical structure homeostasis GO:0060249 97 0.480
blood circulation GO:0008015 26 0.480
Zebrafish
organ growth GO:0035265 56 0.477
response to other organism GO:0051707 293 0.469
Human
cellular response to lipid GO:0071396 20 0.468
protein modification by small protein conjugation GO:0032446 79 0.468
skin development GO:0043588 65 0.467
morphogenesis of a branching epithelium GO:0061138 45 0.465
Mouse
spiracle morphogenesis open tracheal system GO:0035277 22 0.463
positive regulation of protein metabolic process GO:0051247 128 0.462
multicellular organismal homeostasis GO:0048871 41 0.460
central nervous system projection neuron axonogenesis GO:0021952 6 0.459
Mouse
response to endogenous stimulus GO:0009719 119 0.458
synaptic growth at neuromuscular junction GO:0051124 119 0.457
sex differentiation GO:0007548 81 0.457
Worm
regulation of cellular ketone metabolic process GO:0010565 3 0.448
regulation of proteolysis GO:0030162 87 0.447
limb development GO:0060173 1 0.447
Human Mouse
wnt signaling pathway GO:0016055 98 0.444
Human
hair cell differentiation GO:0035315 47 0.444
somatic muscle development GO:0007525 66 0.442
Fly
response to lipid GO:0033993 38 0.438
regulation of gliogenesis GO:0014013 11 0.437
positive regulation of bmp signaling pathway GO:0030513 5 0.436
cuticle pattern formation GO:0035017 27 0.436
outflow tract morphogenesis GO:0003151 4 0.433
regulation of molecular function GO:0065009 217 0.430
response to organic cyclic compound GO:0014070 89 0.430
Mouse
regulation of smoothened signaling pathway GO:0008589 28 0.429
Human Zebrafish Mouse
regulation of protein transport GO:0051223 57 0.429
Mouse
amine metabolic process GO:0009308 12 0.427
male gonad development GO:0008584 9 0.426
mitotic spindle organization GO:0007052 220 0.424
Worm
heart formation GO:0060914 6 0.422
cellular response to external stimulus GO:0071496 66 0.421
regulation of imaginal disc growth GO:0045570 26 0.419
spermatogenesis GO:0007283 200 0.416
Mouse Worm
muscle cell fate commitment GO:0042693 14 0.414
Zebrafish
oocyte differentiation GO:0009994 145 0.409
embryonic pattern specification GO:0009880 174 0.408
segment specification GO:0007379 33 0.404
positive regulation of nervous system development GO:0051962 69 0.400
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 13 0.396
tissue migration GO:0090130 155 0.394
intracellular signal transduction GO:0035556 300 0.394
cellular response to chemical stimulus GO:0070887 199 0.394
Mouse
embryonic hindgut morphogenesis GO:0048619 48 0.393
regulation of cardioblast differentiation GO:0051890 9 0.391
body morphogenesis GO:0010171 2 0.389
mesodermal cell fate commitment GO:0001710 7 0.388
nephron tubule formation GO:0072079 3 0.382
circulatory system process GO:0003013 37 0.378
Zebrafish
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.376
organ induction GO:0001759 3 0.373
somatic stem cell maintenance GO:0035019 14 0.373
negative regulation of cell proliferation GO:0008285 69 0.372
Mouse
catabolic process GO:0009056 409 0.371
positive regulation of programmed cell death GO:0043068 62 0.368
Worm
establishment of protein localization to organelle GO:0072594 62 0.361
Mouse
cellular response to growth factor stimulus GO:0071363 30 0.361
carboxylic acid metabolic process GO:0019752 92 0.359
hindgut morphogenesis GO:0007442 58 0.358
Mouse
neural retina development GO:0003407 4 0.356
regulation of cytoplasmic transport GO:1903649 47 0.355
Mouse
positive regulation of molecular function GO:0044093 136 0.353
regulation of localization GO:0032879 275 0.353
Mouse
positive regulation of signal transduction GO:0009967 223 0.352
Human Zebrafish
regulation of cellular protein metabolic process GO:0032268 243 0.352
regulation of neuroblast proliferation GO:1902692 34 0.350
Mouse
neuromuscular junction development GO:0007528 149 0.349
regulation of cellular localization GO:0060341 136 0.347
Mouse
regulation of phosphorylation GO:0042325 147 0.345
brain development GO:0007420 120 0.344
Zebrafish Mouse
axon development GO:0061564 297 0.344
Zebrafish Mouse
single organism nuclear import GO:1902593 51 0.343
Mouse
cell type specific apoptotic process GO:0097285 38 0.339
Mouse Worm
response to metal ion GO:0010038 23 0.328
response to biotic stimulus GO:0009607 294 0.324
Human
small molecule metabolic process GO:0044281 305 0.322
embryonic axis specification GO:0000578 107 0.320
mesenchyme development GO:0060485 9 0.318
regulation of hemocyte differentiation GO:0045610 22 0.318
regulation of multicellular organism growth GO:0040014 40 0.313
retina morphogenesis in camera type eye GO:0060042 2 0.311
regulation of neurogenesis GO:0050767 158 0.308
Zebrafish Mouse
regulation of glial cell differentiation GO:0045685 1 0.307
protein localization to organelle GO:0033365 82 0.307
Mouse
protein ubiquitination GO:0016567 70 0.305
mesenchymal cell development GO:0014031 1 0.305
cellular amine metabolic process GO:0044106 12 0.304
adipose tissue development GO:0060612 2 0.300
proximal distal pattern formation GO:0009954 15 0.298
Mouse
maintenance of protein location in cell GO:0032507 26 0.298
regulation of stem cell proliferation GO:0072091 40 0.295
Mouse
immune system development GO:0002520 57 0.294
Mouse
imaginal disc growth GO:0007446 37 0.294
response to growth factor GO:0070848 31 0.293
non sensory hair organization GO:0035316 47 0.293
cell fate specification involved in pattern specification GO:0060573 8 0.292
Zebrafish Mouse
eye antennal disc morphogenesis GO:0007455 34 0.290
fusion cell fate specification GO:0035156 4 0.290
chaeta development GO:0022416 97 0.290
morphogenesis of an epithelial bud GO:0060572 3 0.287
Mouse
nuclear division GO:0000280 332 0.285
Worm
regulation of intracellular protein transport GO:0033157 46 0.281
Mouse
hematopoietic or lymphoid organ development GO:0048534 57 0.281
Mouse
protein import into nucleus GO:0006606 51 0.279
Mouse
bolwig s organ development GO:0055034 8 0.278
cell cycle phase transition GO:0044770 140 0.277
intracellular protein transport GO:0006886 104 0.276
Mouse
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.276
protein phosphorylation GO:0006468 169 0.276
regulation of synapse assembly GO:0051963 94 0.274
response to starvation GO:0042594 97 0.273
cell maturation GO:0048469 144 0.269
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.269
organonitrogen compound metabolic process GO:1901564 318 0.268
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.267
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 9 0.267
positive regulation of cellular protein metabolic process GO:0032270 118 0.265
canonical wnt signaling pathway GO:0060070 21 0.265
Human
cellular response to organic cyclic compound GO:0071407 32 0.265
Mouse
neuron fate specification GO:0048665 12 0.263
Zebrafish Mouse
posttranscriptional regulation of gene expression GO:0010608 145 0.259
Zebrafish
tissue homeostasis GO:0001894 36 0.257
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.255
regulation of membrane potential GO:0042391 35 0.255
cell division GO:0051301 248 0.252
determination of bilateral symmetry GO:0009855 13 0.251
regulation of canonical wnt signaling pathway GO:0060828 15 0.247
Human
genital disc anterior posterior pattern formation GO:0035224 8 0.244
chromatin organization GO:0006325 207 0.243
regulation of multicellular organismal development GO:2000026 414 0.240
multicellular organism growth GO:0035264 46 0.230
establishment of localization in cell GO:0051649 402 0.228
Mouse
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.227
negative regulation of growth GO:0045926 84 0.226
establishment or maintenance of cell polarity GO:0007163 167 0.226
cell cycle g1 s phase transition GO:0044843 31 0.225
single organism intracellular transport GO:1902582 207 0.224
Mouse
establishment of cell polarity GO:0030010 40 0.219
regulation of cellular component biogenesis GO:0044087 201 0.219
female sex differentiation GO:0046660 20 0.217
positive regulation of response to stimulus GO:0048584 323 0.215
Human Zebrafish
reproductive system development GO:0061458 74 0.215
Mouse Worm
imaginal disc derived leg joint morphogenesis GO:0016348 15 0.215
regulation of embryonic development GO:0045995 68 0.214
negative regulation of cell cycle process GO:0010948 109 0.213
periodic partitioning GO:0007365 29 0.213
neuron recognition GO:0008038 101 0.213
tripartite regional subdivision GO:0007351 103 0.211
positive regulation of cell communication GO:0010647 250 0.209
Human Zebrafish
autophagy GO:0006914 108 0.207
localization of cell GO:0051674 257 0.207
Mouse Worm
nuclear transport GO:0051169 72 0.206
Mouse
haltere disc development GO:0035216 10 0.206
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.206
genital disc sexually dimorphic development GO:0035263 4 0.204
regulation of tube architecture open tracheal system GO:0035152 68 0.201
cell adhesion GO:0007155 136 0.199
positive regulation of catabolic process GO:0009896 105 0.199
epidermis development GO:0008544 65 0.198
regulation of transport GO:0051049 181 0.198
Mouse
organelle assembly GO:0070925 198 0.195
pericardium morphogenesis GO:0003344 2 0.193
protein modification by small protein conjugation or removal GO:0070647 106 0.192
regulation of cellular amino acid metabolic process GO:0006521 0 0.192
signal release GO:0023061 49 0.191
rhythmic process GO:0048511 106 0.189
oocyte development GO:0048599 124 0.188
regulation of cellular amine metabolic process GO:0033238 3 0.187
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.186
negative regulation of stem cell differentiation GO:2000737 8 0.185
nuclear import GO:0051170 51 0.184
Mouse
determination of ventral identity GO:0048264 1 0.184
embryonic hemopoiesis GO:0035162 26 0.183
regulation of catabolic process GO:0009894 170 0.183
epithelium migration GO:0090132 148 0.183
proteoglycan biosynthetic process GO:0030166 10 0.179
cellular response to dna damage stimulus GO:0006974 223 0.177
maintenance of protein location GO:0045185 28 0.177
metal ion homeostasis GO:0055065 44 0.176
cardiac cell fate commitment GO:0060911 17 0.176
negative regulation of mitotic cell cycle GO:0045930 109 0.175
post embryonic hemopoiesis GO:0035166 17 0.175
positive regulation of phosphorylation GO:0042327 87 0.172
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.172
cellular response to hormone stimulus GO:0032870 44 0.171
determination of dorsal ventral asymmetry GO:0048262 3 0.171
regulation of notch signaling pathway GO:0008593 100 0.169
defense response GO:0006952 300 0.169
positive regulation of cell death GO:0010942 69 0.168
Worm
ectodermal placode development GO:0071696 4 0.168
negative regulation of developmental growth GO:0048640 64 0.168
hindgut development GO:0061525 58 0.167
Mouse
cellular response to oxygen containing compound GO:1901701 79 0.166
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.166

ci disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.539
Human
cardiovascular system disease DOID:1287 0 0.539
auditory system disease DOID:2742 0 0.272
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.272
nonsyndromic deafness DOID:0050563 0 0.272
sensory system disease DOID:0050155 0 0.272
nervous system disease DOID:863 0 0.272