Drosophila melanogaster

5 known processes

aralar1 (Dmel_CG2139)

CG2139 gene product from transcript CG2139-RC

(Aliases: aralar,BcDNA:GH07418,Dmel\CG2139,DmAralar,CG2139)

aralar1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of gene expression GO:0010629 387 0.171
small molecule metabolic process GO:0044281 305 0.164
Human
organic substance catabolic process GO:1901575 308 0.115
negative regulation of biosynthetic process GO:0009890 277 0.106
secondary metabolic process GO:0019748 75 0.105
organonitrogen compound metabolic process GO:1901564 318 0.104
Human
response to oxygen containing compound GO:1901700 200 0.102
organic substance transport GO:0071702 257 0.102
Human Yeast Mouse
steroid catabolic process GO:0006706 1 0.095
carboxylic acid metabolic process GO:0019752 92 0.093
single organism catabolic process GO:0044712 228 0.092
synaptic transmission GO:0007268 288 0.089
oxoacid metabolic process GO:0043436 103 0.088
cellular aldehyde metabolic process GO:0006081 10 0.083
response to organic substance GO:0010033 284 0.082
thioester metabolic process GO:0035383 3 0.072
catabolic process GO:0009056 409 0.068
negative regulation of cellular metabolic process GO:0031324 382 0.064
response to nutrient levels GO:0031667 114 0.063
ion transport GO:0006811 145 0.062
Human Yeast Mouse
single organism intracellular transport GO:1902582 207 0.059
Human Mouse
protein localization GO:0008104 284 0.057
negative regulation of rna metabolic process GO:0051253 251 0.055
cellular catabolic process GO:0044248 372 0.054
single organism biosynthetic process GO:0044711 206 0.052
Human
negative regulation of cellular biosynthetic process GO:0031327 277 0.052
cellular response to starvation GO:0009267 61 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.049
response to organophosphorus GO:0046683 2 0.049
cell death GO:0008219 279 0.049
sulfur compound biosynthetic process GO:0044272 16 0.047
monocarboxylic acid transport GO:0015718 3 0.046
establishment of localization in cell GO:0051649 402 0.046
Human Mouse
oxidation reduction process GO:0055114 123 0.046
Human Mouse
response to alcohol GO:0097305 95 0.045
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.045
organonitrogen compound biosynthetic process GO:1901566 117 0.045
Human
nucleotide metabolic process GO:0009117 161 0.044
Human
negative regulation of nucleic acid templated transcription GO:1903507 240 0.044
organic hydroxy compound metabolic process GO:1901615 83 0.044
cellular response to nutrient levels GO:0031669 62 0.043
regulation of cell death GO:0010941 173 0.042
nucleoside phosphate metabolic process GO:0006753 162 0.042
Human
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.041
negative regulation of rna biosynthetic process GO:1902679 240 0.041
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.040
intracellular transport GO:0046907 228 0.040
Human Mouse
macromolecule catabolic process GO:0009057 161 0.039
protein transport GO:0015031 155 0.039
single organism behavior GO:0044708 391 0.039
response to abiotic stimulus GO:0009628 341 0.038
organophosphate metabolic process GO:0019637 195 0.038
Human
carboxylic acid transport GO:0046942 18 0.035
Human Yeast Mouse
pyridine containing compound metabolic process GO:0072524 3 0.035
death GO:0016265 284 0.034
organic cyclic compound catabolic process GO:1901361 168 0.034
androgen metabolic process GO:0008209 1 0.034
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.034
nicotinamide nucleotide metabolic process GO:0046496 2 0.034
defense response GO:0006952 300 0.034
nucleoside metabolic process GO:0009116 127 0.033
Human
organic acid metabolic process GO:0006082 103 0.033
rna splicing GO:0008380 83 0.031
response to extracellular stimulus GO:0009991 116 0.031
regulation of mrna processing GO:0050684 71 0.031
telencephalon development GO:0021537 2 0.031
purine containing compound metabolic process GO:0072521 155 0.029
Human
monocarboxylic acid metabolic process GO:0032787 29 0.029
dephosphorylation GO:0016311 51 0.028
ocellus pigment biosynthetic process GO:0008055 19 0.028
glycosyl compound metabolic process GO:1901657 127 0.028
Human
regulation of cellular protein metabolic process GO:0032268 243 0.027
lipid metabolic process GO:0006629 121 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.027
regulation of programmed cell death GO:0043067 152 0.027
nucleoside monophosphate metabolic process GO:0009123 52 0.026
Human
regulation of mrna metabolic process GO:1903311 72 0.026
response to ethanol GO:0045471 59 0.026
mrna metabolic process GO:0016071 124 0.026
forebrain development GO:0030900 2 0.026
cell type specific apoptotic process GO:0097285 38 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
establishment of protein localization GO:0045184 163 0.025
regulation of molecular function GO:0065009 217 0.025
response to organic cyclic compound GO:0014070 89 0.025
central nervous system development GO:0007417 201 0.024
intracellular protein transport GO:0006886 104 0.024
heterocycle catabolic process GO:0046700 166 0.024
protein modification process GO:0036211 438 0.024
aromatic compound catabolic process GO:0019439 166 0.024
cellular response to organic substance GO:0071310 132 0.024
head development GO:0060322 135 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
positive regulation of cell communication GO:0010647 250 0.023
anion transport GO:0006820 41 0.023
Human Yeast Mouse
negative regulation of transcription dna templated GO:0045892 237 0.023
regulation of response to stress GO:0080134 200 0.023
regulation of apoptotic process GO:0042981 130 0.023
cellular macromolecule localization GO:0070727 220 0.023
intracellular signal transduction GO:0035556 300 0.022
body morphogenesis GO:0010171 2 0.022
developmental growth GO:0048589 280 0.022
defense response to other organism GO:0098542 225 0.022
ribose phosphate metabolic process GO:0019693 145 0.022
Human
carbohydrate derivative metabolic process GO:1901135 217 0.022
Human
protein targeting GO:0006605 64 0.022
cytoplasmic transport GO:0016482 130 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
Human
cellular nitrogen compound catabolic process GO:0044270 165 0.022
mrna processing GO:0006397 104 0.022
mrna splicing via spliceosome GO:0000398 73 0.021
response to endogenous stimulus GO:0009719 119 0.021
organelle fission GO:0048285 340 0.021
regulation of cell cycle GO:0051726 291 0.021
adult behavior GO:0030534 137 0.021
cellular protein modification process GO:0006464 438 0.021
regulation of proteolysis GO:0030162 87 0.021
positive regulation of signaling GO:0023056 243 0.021
meiotic nuclear division GO:0007126 151 0.020
regulation of growth GO:0040008 233 0.020
single organism carbohydrate metabolic process GO:0044723 72 0.020
chromosome organization GO:0051276 360 0.020
ocellus pigmentation GO:0033060 19 0.019
nuclear division GO:0000280 332 0.019
programmed cell death GO:0012501 257 0.019
epithelial cell differentiation GO:0030855 322 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
macromolecular complex assembly GO:0065003 256 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
synapse organization GO:0050808 196 0.019
regulation of rna splicing GO:0043484 69 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
Human
apoptotic process GO:0006915 159 0.018
cellular amine metabolic process GO:0044106 12 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
rna processing GO:0006396 147 0.018
pigment biosynthetic process GO:0046148 36 0.018
cellular protein localization GO:0034613 160 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
Human
appendage development GO:0048736 401 0.017
ommochrome metabolic process GO:0046152 19 0.017
neurological system process GO:0050877 358 0.016
lipid modification GO:0030258 24 0.016
lipid localization GO:0010876 54 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
response to starvation GO:0042594 97 0.016
regulation of immune system process GO:0002682 176 0.016
mitochondrion organization GO:0007005 65 0.016
lipid storage GO:0019915 38 0.016
regulation of multicellular organismal development GO:2000026 414 0.016
wing disc morphogenesis GO:0007472 344 0.016
regulation of catabolic process GO:0009894 170 0.016
regulation of defense response GO:0031347 102 0.016
pigmentation GO:0043473 75 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
lipid catabolic process GO:0016042 21 0.016
proteolysis GO:0006508 192 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
very long chain fatty acid metabolic process GO:0000038 4 0.016
imaginal disc derived appendage development GO:0048737 399 0.015
regulation of protein metabolic process GO:0051246 256 0.015
organic acid transport GO:0015849 18 0.015
Human Yeast Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
secretion by cell GO:0032940 101 0.015
response to light stimulus GO:0009416 124 0.015
ommochrome biosynthetic process GO:0006727 19 0.015
nuclear transport GO:0051169 72 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
regulation of mrna splicing via spliceosome GO:0048024 64 0.015
organic anion transport GO:0015711 28 0.015
Human Yeast Mouse
connective tissue development GO:0061448 3 0.015
sensory perception GO:0007600 196 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
cellular response to chemical stimulus GO:0070887 199 0.014
acyl coa metabolic process GO:0006637 3 0.014
single organism cellular localization GO:1902580 180 0.014
positive regulation of gene expression GO:0010628 290 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
endocytosis GO:0006897 310 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
Human
kidney development GO:0001822 3 0.014
vesicle mediated transport GO:0016192 381 0.014
organic hydroxy compound catabolic process GO:1901616 4 0.014
immune response GO:0006955 246 0.014
carbohydrate metabolic process GO:0005975 82 0.014
regulation of immune response GO:0050776 118 0.014
epithelium migration GO:0090132 148 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
cellular response to extracellular stimulus GO:0031668 64 0.014
regionalization GO:0003002 416 0.014
response to biotic stimulus GO:0009607 294 0.014
cell motility GO:0048870 251 0.014
negative regulation of cell communication GO:0010648 223 0.014
phagocytosis GO:0006909 215 0.014
developmental pigmentation GO:0048066 68 0.014
pigment metabolic process GO:0042440 84 0.014
response to hexose GO:0009746 3 0.013
appendage morphogenesis GO:0035107 397 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
spindle organization GO:0007051 253 0.013
camera type eye development GO:0043010 4 0.013
brain development GO:0007420 120 0.013
energy derivation by oxidation of organic compounds GO:0015980 32 0.013
Human Mouse
negative regulation of protein metabolic process GO:0051248 85 0.013
response to lipopolysaccharide GO:0032496 4 0.013
organophosphate catabolic process GO:0046434 112 0.013
cell proliferation GO:0008283 299 0.013
chromatin organization GO:0006325 207 0.013
meiotic cell cycle GO:0051321 171 0.013
response to lipid GO:0033993 38 0.013
mushroom body development GO:0016319 70 0.013
cellular lipid metabolic process GO:0044255 83 0.013
response to external biotic stimulus GO:0043207 293 0.013
pyridine nucleotide metabolic process GO:0019362 2 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
Human
positive regulation of catabolic process GO:0009896 105 0.013
positive regulation of cell motility GO:2000147 3 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
Human
ocellus pigment metabolic process GO:0046158 19 0.013
purine nucleoside metabolic process GO:0042278 127 0.012
Human
sex differentiation GO:0007548 81 0.012
cellular response to external stimulus GO:0071496 66 0.012
protein localization to organelle GO:0033365 82 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
protein catabolic process GO:0030163 101 0.012
response to monosaccharide GO:0034284 4 0.012
organelle assembly GO:0070925 198 0.012
positive regulation of cell proliferation GO:0008284 47 0.012
generation of precursor metabolites and energy GO:0006091 42 0.012
Human Mouse
homeostatic process GO:0042592 199 0.012
synapse assembly GO:0007416 143 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
Human
regulation of gene expression epigenetic GO:0040029 128 0.012
regulation of cell cycle process GO:0010564 181 0.012
regulation of localization GO:0032879 275 0.012
response to other organism GO:0051707 293 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
regulation of innate immune response GO:0045088 71 0.012
cellular response to organic cyclic compound GO:0071407 32 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
nucleoside catabolic process GO:0009164 112 0.012
cellular protein complex assembly GO:0043623 71 0.012
positive regulation of cell death GO:0010942 69 0.012
negative regulation of signal transduction GO:0009968 206 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
reproductive system development GO:0061458 74 0.011
inorganic cation transmembrane transport GO:0098662 61 0.011
detection of stimulus GO:0051606 156 0.011
cellular homeostasis GO:0019725 80 0.011
cell division GO:0051301 248 0.011
positive regulation of signal transduction GO:0009967 223 0.011
oxidoreduction coenzyme metabolic process GO:0006733 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
Human
vitamin metabolic process GO:0006766 2 0.011
cell adhesion GO:0007155 136 0.011
gene silencing GO:0016458 138 0.011
chromatin modification GO:0016568 147 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
monocarboxylic acid biosynthetic process GO:0072330 7 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
regulation of hormone levels GO:0010817 40 0.011
spermatogenesis GO:0007283 200 0.011
compound eye development GO:0048749 307 0.011
regulation of cell proliferation GO:0042127 163 0.011
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.010
Human
response to radiation GO:0009314 155 0.010
negative regulation of signaling GO:0023057 219 0.010
cellular response to hexose stimulus GO:0071331 1 0.010
fatty acid metabolic process GO:0006631 20 0.010
cation transport GO:0006812 110 0.010
cellular ketone metabolic process GO:0042180 24 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
purine nucleoside catabolic process GO:0006152 112 0.010
regulation of transport GO:0051049 181 0.010
antimicrobial humoral response GO:0019730 99 0.010
ribonucleoside monophosphate metabolic process GO:0009161 51 0.010
Human
nephron development GO:0072006 3 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
response to nitrogen compound GO:1901698 90 0.010

aralar1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.039
Human
inherited metabolic disorder DOID:655 0 0.031
Human
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013