Drosophila melanogaster

50 known processes

Fer1HCH (Dmel_CG2216)

Ferritin 1 heavy chain homologue

(Aliases: Fer1,FerHCH,fer1hch,T9,l(3)00451,CG2216,FER1,Fer-L,FER1HCH,Dmel\CG2216,Fer1HC,T21,BEST:LD36673,1HCH,HCH,l(3)j10B4)

Fer1HCH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circadian rhythm GO:0007623 105 0.591
Fly
cell proliferation GO:0008283 299 0.439
cellular iron ion homeostasis GO:0006879 3 0.399
response to abiotic stimulus GO:0009628 341 0.360
determination of adult lifespan GO:0008340 137 0.304
aging GO:0007568 143 0.300
response to metal ion GO:0010038 23 0.284
locomotory behavior GO:0007626 176 0.279
Fly
regulation of protein metabolic process GO:0051246 256 0.271
cellular transition metal ion homeostasis GO:0046916 9 0.259
hormone metabolic process GO:0042445 33 0.247
metal ion homeostasis GO:0055065 44 0.246
regulation of intracellular signal transduction GO:1902531 236 0.222
innate immune response GO:0045087 144 0.215
Fly
immune response GO:0006955 246 0.186
Fly
iron ion homeostasis GO:0055072 5 0.180
nucleocytoplasmic transport GO:0006913 72 0.179
positive regulation of response to stimulus GO:0048584 323 0.165
multicellular organismal aging GO:0010259 140 0.163
developmental programmed cell death GO:0010623 138 0.154
eye development GO:0001654 323 0.153
defense response GO:0006952 300 0.148
Fly
muscle structure development GO:0061061 224 0.147
protein catabolic process GO:0030163 101 0.126
growth GO:0040007 359 0.125
protein localization GO:0008104 284 0.124
organic substance transport GO:0071702 257 0.116
wound healing GO:0042060 75 0.116
Fly
intracellular transport GO:0046907 228 0.110
response to transition metal nanoparticle GO:1990267 9 0.105
transition metal ion transport GO:0000041 16 0.105
response to wounding GO:0009611 94 0.104
Fly
single organism behavior GO:0044708 391 0.104
Fly
regulation of transport GO:0051049 181 0.103
regulation of secretion GO:0051046 44 0.099
death GO:0016265 284 0.096
cytoplasmic transport GO:0016482 130 0.095
establishment of localization in cell GO:0051649 402 0.094
cellular ion homeostasis GO:0006873 39 0.094
regulation of cellular localization GO:0060341 136 0.092
cellular component assembly involved in morphogenesis GO:0010927 151 0.091
morphogenesis of a polarized epithelium GO:0001738 93 0.090
intracellular signal transduction GO:0035556 300 0.088
post embryonic appendage morphogenesis GO:0035120 385 0.085
tissue death GO:0016271 102 0.084
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.083
regionalization GO:0003002 416 0.081
morphogenesis of an epithelium GO:0002009 276 0.078
secretion GO:0046903 109 0.077
secretion by cell GO:0032940 101 0.073
regulation of cell differentiation GO:0045595 302 0.073
response to organic substance GO:0010033 284 0.072
rna localization GO:0006403 115 0.071
establishment of protein localization GO:0045184 163 0.067
cellular metal ion homeostasis GO:0006875 31 0.067
ketone biosynthetic process GO:0042181 16 0.066
trna modification GO:0006400 2 0.065
single organism intracellular transport GO:1902582 207 0.065
wnt signaling pathway GO:0016055 98 0.064
nuclear transport GO:0051169 72 0.064
imaginal disc derived appendage development GO:0048737 399 0.063
homeostatic process GO:0042592 199 0.063
protein transport GO:0015031 155 0.062
single organism cellular localization GO:1902580 180 0.062
positive regulation of signaling GO:0023056 243 0.061
regulation of organelle organization GO:0033043 196 0.060
imaginal disc derived appendage morphogenesis GO:0035114 395 0.059
response to inorganic substance GO:0010035 44 0.058
positive regulation of signal transduction GO:0009967 223 0.057
circadian behavior GO:0048512 76 0.057
Fly
regulation of hormone levels GO:0010817 40 0.057
tissue morphogenesis GO:0048729 297 0.056
embryo development ending in birth or egg hatching GO:0009792 152 0.055
regulation of cell cycle GO:0051726 291 0.053
macromolecule catabolic process GO:0009057 161 0.053
meiotic nuclear division GO:0007126 151 0.053
establishment of tissue polarity GO:0007164 87 0.053
cell death GO:0008219 279 0.051
nitrogen compound transport GO:0071705 85 0.051
mapk cascade GO:0000165 107 0.050
organelle assembly GO:0070925 198 0.050
lipid metabolic process GO:0006629 121 0.050
chemical homeostasis GO:0048878 92 0.050
positive regulation of growth GO:0045927 75 0.050
ion homeostasis GO:0050801 55 0.049
positive regulation of cellular component organization GO:0051130 156 0.048
steroid biosynthetic process GO:0006694 16 0.047
regulation of body fluid levels GO:0050878 14 0.047
Fly
cation transport GO:0006812 110 0.047
regulation of catabolic process GO:0009894 170 0.047
humoral immune response GO:0006959 117 0.046
Fly
negative regulation of mitotic cell cycle GO:0045930 109 0.046
cellular homeostasis GO:0019725 80 0.045
cellular response to abiotic stimulus GO:0071214 58 0.045
regulation of cell proliferation GO:0042127 163 0.045
imaginal disc derived wing morphogenesis GO:0007476 337 0.044
protein complex biogenesis GO:0070271 201 0.044
steroid metabolic process GO:0008202 20 0.044
muscle organ development GO:0007517 127 0.043
salivary gland development GO:0007431 162 0.043
small molecule metabolic process GO:0044281 305 0.042
protein secretion GO:0009306 45 0.041
regulation of protein modification process GO:0031399 112 0.040
negative regulation of signal transduction GO:0009968 206 0.040
regulation of localization GO:0032879 275 0.040
kidney development GO:0001822 3 0.039
salivary gland cell autophagic cell death GO:0035071 83 0.038
positive regulation of developmental growth GO:0048639 62 0.038
wing disc morphogenesis GO:0007472 344 0.036
vesicle mediated transport GO:0016192 381 0.036
negative regulation of signaling GO:0023057 219 0.036
negative regulation of response to stimulus GO:0048585 258 0.035
cellular response to chemical stimulus GO:0070887 199 0.034
appendage morphogenesis GO:0035107 397 0.033
autophagy GO:0006914 108 0.033
cellular macromolecule localization GO:0070727 220 0.033
connective tissue development GO:0061448 3 0.032
substrate adhesion dependent cell spreading GO:0034446 2 0.032
histolysis GO:0007559 102 0.032
protein complex assembly GO:0006461 200 0.032
positive regulation of multicellular organismal process GO:0051240 143 0.032
positive regulation of cell communication GO:0010647 250 0.032
protein processing GO:0016485 68 0.032
regulation of molecular function GO:0065009 217 0.032
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
establishment of planar polarity GO:0001736 87 0.032
larval development GO:0002164 104 0.031
protein modification process GO:0036211 438 0.031
cellular chemical homeostasis GO:0055082 40 0.030
regulation of wnt signaling pathway GO:0030111 68 0.029
regulation of response to external stimulus GO:0032101 115 0.029
regulation of mapk cascade GO:0043408 92 0.029
regulation of developmental growth GO:0048638 174 0.029
coagulation GO:0050817 10 0.029
Fly
positive regulation of developmental process GO:0051094 143 0.028
protein k48 linked ubiquitination GO:0070936 3 0.028
positive regulation of gene expression GO:0010628 290 0.028
regulation of response to stress GO:0080134 200 0.027
gland development GO:0048732 191 0.027
sex differentiation GO:0007548 81 0.027
cellular catabolic process GO:0044248 372 0.026
regulation of neurogenesis GO:0050767 158 0.026
developmental growth GO:0048589 280 0.026
organic substance catabolic process GO:1901575 308 0.026
establishment or maintenance of cell polarity GO:0007163 167 0.025
lipid biosynthetic process GO:0008610 46 0.025
proteolysis GO:0006508 192 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.025
response to temperature stimulus GO:0009266 106 0.024
non sensory hair organization GO:0035316 47 0.024
regulation of catalytic activity GO:0050790 185 0.024
dorsal ventral pattern formation GO:0009953 133 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.024
response to oxygen containing compound GO:1901700 200 0.024
cellular protein catabolic process GO:0044257 83 0.024
negative regulation of cell communication GO:0010648 223 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
epithelial cell differentiation GO:0030855 322 0.023
regulation of anatomical structure size GO:0090066 163 0.023
gliogenesis GO:0042063 80 0.023
negative regulation of organelle organization GO:0010639 56 0.023
biological adhesion GO:0022610 138 0.022
positive regulation of protein kinase activity GO:0045860 25 0.022
molting cycle GO:0042303 56 0.022
neurological system process GO:0050877 358 0.022
camera type eye development GO:0043010 4 0.022
appendage development GO:0048736 401 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
multicellular organismal homeostasis GO:0048871 41 0.021
nuclear export GO:0051168 24 0.021
body morphogenesis GO:0010171 2 0.021
embryonic morphogenesis GO:0048598 206 0.021
tube morphogenesis GO:0035239 191 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
dendrite morphogenesis GO:0048813 199 0.021
glycosyl compound metabolic process GO:1901657 127 0.021
negative regulation of cell proliferation GO:0008285 69 0.021
localization of cell GO:0051674 257 0.020
spermatogenesis GO:0007283 200 0.020
regulation of phosphorylation GO:0042325 147 0.020
cation homeostasis GO:0055080 51 0.020
sensory perception of pain GO:0019233 4 0.020
protein maturation GO:0051604 71 0.020
cell cycle arrest GO:0007050 4 0.020
ncrna metabolic process GO:0034660 43 0.020
regulation of cell cycle process GO:0010564 181 0.020
defense response to bacterium GO:0042742 178 0.020
dna integrity checkpoint GO:0031570 81 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
establishment of organelle localization GO:0051656 122 0.019
gene silencing GO:0016458 138 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
negative regulation of cell cycle GO:0045786 116 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
regulation of cytoskeleton organization GO:0051493 89 0.019
mitotic spindle organization GO:0007052 220 0.018
protein ubiquitination GO:0016567 70 0.018
regulation of secretion by cell GO:1903530 39 0.018
negative regulation of gene expression GO:0010629 387 0.018
defense response to gram negative bacterium GO:0050829 94 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
negative regulation of cell cycle phase transition GO:1901988 103 0.018
catabolic process GO:0009056 409 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
nucleoside metabolic process GO:0009116 127 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
macroautophagy GO:0016236 42 0.017
regulation of cell division GO:0051302 72 0.017
response to hexose GO:0009746 3 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
reproductive system development GO:0061458 74 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
septate junction assembly GO:0019991 26 0.017
response to bacterium GO:0009617 198 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
central nervous system development GO:0007417 201 0.016
cell adhesion GO:0007155 136 0.016
regulation of proteolysis GO:0030162 87 0.016
circulatory system process GO:0003013 37 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
extracellular matrix organization GO:0030198 32 0.016
chromosome organization GO:0051276 360 0.016
exocrine system development GO:0035272 162 0.016
cell cycle phase transition GO:0044770 140 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
chromatin organization GO:0006325 207 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
rhythmic behavior GO:0007622 76 0.015
Fly
actin cytoskeleton organization GO:0030036 206 0.015
response to other organism GO:0051707 293 0.015
regulation of immune response GO:0050776 118 0.015
anterior posterior pattern specification GO:0009952 136 0.015
cellular response to radiation GO:0071478 52 0.015
salivary gland histolysis GO:0035070 88 0.015
response to external biotic stimulus GO:0043207 293 0.015
mitochondrion organization GO:0007005 65 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
circulatory system development GO:0072359 82 0.015
embryonic pattern specification GO:0009880 174 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
rna processing GO:0006396 147 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
positive regulation of mitochondrion organization GO:0010822 8 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
cellular cation homeostasis GO:0030003 38 0.014
autophagic vacuole assembly GO:0000045 2 0.014
striated muscle myosin thick filament assembly GO:0071688 3 0.014
organophosphate metabolic process GO:0019637 195 0.014
response to organic cyclic compound GO:0014070 89 0.014
actin filament based process GO:0030029 220 0.014
regulation of growth GO:0040008 233 0.014
negative regulation of molecular function GO:0044092 51 0.014
membrane organization GO:0061024 112 0.014
male gamete generation GO:0048232 201 0.014
regulation of nervous system development GO:0051960 248 0.013
response to biotic stimulus GO:0009607 294 0.013
hormone biosynthetic process GO:0042446 20 0.013
muscle tissue development GO:0060537 30 0.013
macromolecular complex assembly GO:0065003 256 0.013
cellular protein localization GO:0034613 160 0.013
protein localization to nucleus GO:0034504 55 0.013
nuclear division GO:0000280 332 0.013
autophagic cell death GO:0048102 83 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
brain development GO:0007420 120 0.013
chaeta development GO:0022416 97 0.013
Fly
multicellular organism growth GO:0035264 46 0.013
peptide hormone processing GO:0016486 2 0.013
negative regulation of stem cell proliferation GO:2000647 30 0.013
negative regulation of catalytic activity GO:0043086 42 0.013
wing disc pattern formation GO:0035222 66 0.013
organic acid metabolic process GO:0006082 103 0.013
epithelial cell development GO:0002064 274 0.013
positive regulation of catabolic process GO:0009896 105 0.013
protein targeting to nucleus GO:0044744 51 0.012
mrna metabolic process GO:0016071 124 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
defense response to other organism GO:0098542 225 0.012
instar larval development GO:0002168 55 0.012
regulation of programmed cell death GO:0043067 152 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
adult locomotory behavior GO:0008344 76 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
ion transport GO:0006811 145 0.012
response to high light intensity GO:0009644 1 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
gland morphogenesis GO:0022612 145 0.012
negative regulation of insulin secretion GO:0046676 1 0.012
blastoderm segmentation GO:0007350 159 0.012
deactivation of rhodopsin mediated signaling GO:0016059 17 0.012
eye morphogenesis GO:0048592 260 0.012
intracellular mrna localization GO:0008298 66 0.012
centrosome duplication GO:0051298 121 0.012
salivary gland morphogenesis GO:0007435 145 0.012
regulation of hydrolase activity GO:0051336 97 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
negative regulation of compound eye retinal cell programmed cell death GO:0046673 7 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
long term memory GO:0007616 62 0.011
single organism cell adhesion GO:0098602 47 0.011
dna metabolic process GO:0006259 227 0.011
response to copper ion GO:0046688 4 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
cellular protein modification process GO:0006464 438 0.011
response to oxygen levels GO:0070482 59 0.011
cellular response to hormone stimulus GO:0032870 44 0.011
regulation of intracellular transport GO:0032386 64 0.011
regulation of meiosis GO:0040020 3 0.011
cell cycle checkpoint GO:0000075 95 0.011
reproductive structure development GO:0048608 74 0.011
sterol metabolic process GO:0016125 12 0.011
negative regulation of autophagy GO:0010507 16 0.011
regulation of cytoplasmic transport GO:1903649 47 0.011
regulation of intracellular protein transport GO:0033157 46 0.011
lateral inhibition GO:0046331 206 0.011
neural precursor cell proliferation GO:0061351 75 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
regulation of immune system process GO:0002682 176 0.011
response to monosaccharide GO:0034284 4 0.011
regulation of cell death GO:0010941 173 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
positive regulation of lipid metabolic process GO:0045834 4 0.011
cell aging GO:0007569 2 0.010
immune system process GO:0002376 347 0.010
Fly
endomembrane system organization GO:0010256 119 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
cilium assembly GO:0042384 38 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.010
rna transport GO:0050658 46 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
positive regulation of biosynthetic process GO:0009891 316 0.010

Fer1HCH disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.074
disease of cellular proliferation DOID:14566 0 0.036
cancer DOID:162 0 0.022
organ system cancer DOID:0050686 0 0.022
immune system disease DOID:2914 0 0.014
anemia DOID:2355 0 0.014
hematopoietic system disease DOID:74 0 0.014
nervous system disease DOID:863 0 0.013
aplastic anemia DOID:12449 0 0.012
bone marrow disease DOID:4961 0 0.012