Drosophila melanogaster

457 known processes

Rac1 (Dmel_CG2248)

CG2248 gene product from transcript CG2248-RA

(Aliases: DRac1,Rac GTPase,rac,Dmel\CG2248,GTPase Rac1,DRac,CG2248,Drac1,rac1,D-Rac1,Rac-1,DmRAC,2248,Drac,RAC1,Dmrac1,D-Rac 1,Drac1a,dRac1,Rac,DmRAC1,DracA,Dm Rac1,D-Rac,DRacA,dRac,RacA)

Rac1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
columnar cuboidal epithelial cell development GO:0002066 249 1.000
ovarian follicle cell migration GO:0007297 121 1.000
epithelial cell migration GO:0010631 148 1.000
initiation of dorsal closure GO:0007392 12 1.000
ovarian follicle cell development GO:0030707 248 1.000
cell migration GO:0016477 238 1.000
border follicle cell migration GO:0007298 113 1.000
tissue migration GO:0090130 155 1.000
columnar cuboidal epithelial cell differentiation GO:0002065 256 1.000
tissue morphogenesis GO:0048729 297 1.000
ameboidal type cell migration GO:0001667 151 1.000
axonogenesis GO:0007409 290 1.000
taxis GO:0042330 304 1.000
chorion containing eggshell formation GO:0007304 105 1.000
dendrite development GO:0016358 204 1.000
morphogenesis of an epithelium GO:0002009 276 1.000
imaginal disc derived appendage morphogenesis GO:0035114 395 1.000
axon development GO:0061564 297 1.000
dorsal appendage formation GO:0046843 47 1.000
eggshell formation GO:0030703 105 0.999
striated muscle cell differentiation GO:0051146 90 0.999
muscle structure development GO:0061061 224 0.999
post embryonic appendage morphogenesis GO:0035120 385 0.999
dendrite morphogenesis GO:0048813 199 0.999
neuron projection guidance GO:0097485 241 0.999
axon guidance GO:0007411 233 0.999
encapsulation of foreign target GO:0035010 38 0.999
epithelial cell development GO:0002064 274 0.999
embryonic morphogenesis GO:0048598 206 0.999
epithelial cell differentiation GO:0030855 322 0.999
epithelium migration GO:0090132 148 0.999
dorsal closure GO:0007391 79 0.999
regulation of anatomical structure morphogenesis GO:0022603 242 0.999
localization of cell GO:0051674 257 0.999
syncytium formation by plasma membrane fusion GO:0000768 43 0.998
cell motility GO:0048870 251 0.998
axon midline choice point recognition GO:0016199 26 0.998
establishment of planar polarity GO:0001736 87 0.997
chemotaxis GO:0006935 249 0.996
tube development GO:0035295 244 0.996
compound eye morphogenesis GO:0001745 249 0.996
digestive tract morphogenesis GO:0048546 127 0.995
neurological system process GO:0050877 358 0.994
regulation of developmental growth GO:0048638 174 0.994
Fly
appendage development GO:0048736 401 0.994
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.993
regulation of cell differentiation GO:0045595 302 0.993
gastrulation GO:0007369 70 0.993
embryonic development via the syncytial blastoderm GO:0001700 148 0.992
hemocyte differentiation GO:0042386 38 0.992
guanosine containing compound catabolic process GO:1901069 74 0.990
cell projection assembly GO:0030031 94 0.988
cortical actin cytoskeleton organization GO:0030866 24 0.987
homeostatic process GO:0042592 199 0.987
Zebrafish Rat
reproductive behavior GO:0019098 122 0.986
Fly
axon extension GO:0048675 32 0.986
regulation of localization GO:0032879 275 0.986
Human Zebrafish Mouse Worm Fly
eggshell chorion assembly GO:0007306 66 0.986
positive regulation of transcription dna templated GO:0045893 266 0.986
regulation of neuron projection development GO:0010975 69 0.985
photoreceptor cell differentiation GO:0046530 170 0.984
morphogenesis of embryonic epithelium GO:0016331 94 0.984
actin cytoskeleton organization GO:0030036 206 0.983
positive regulation of molecular function GO:0044093 136 0.983
secretion GO:0046903 109 0.983
multi organism reproductive behavior GO:0044705 121 0.982
Fly
phenol containing compound metabolic process GO:0018958 57 0.980
positive regulation of cell motility GO:2000147 3 0.980
Human Zebrafish Mouse
establishment or maintenance of cell polarity GO:0007163 167 0.980
immune system process GO:0002376 347 0.980
spermatogenesis GO:0007283 200 0.979
Fly
rhabdomere development GO:0042052 38 0.978
developmental growth GO:0048589 280 0.977
head development GO:0060322 135 0.977
Mouse
oocyte development GO:0048599 124 0.977
Fly
myoblast fusion GO:0007520 43 0.977
muscle cell differentiation GO:0042692 103 0.976
central nervous system development GO:0007417 201 0.976
positive regulation of macromolecule metabolic process GO:0010604 405 0.975
regulation of cell morphogenesis GO:0022604 163 0.975
positive regulation of cell projection organization GO:0031346 29 0.975
cell growth GO:0016049 108 0.973
mushroom body development GO:0016319 70 0.973
oocyte differentiation GO:0009994 145 0.971
Fly
compound eye development GO:0048749 307 0.970
tube morphogenesis GO:0035239 191 0.969
regulation of embryonic cell shape GO:0016476 30 0.969
wing disc morphogenesis GO:0007472 344 0.969
synaptic growth at neuromuscular junction GO:0051124 119 0.968
Fly
cognition GO:0050890 141 0.968
response to external biotic stimulus GO:0043207 293 0.965
Fly
melanotic encapsulation of foreign target GO:0035011 30 0.963
open tracheal system development GO:0007424 204 0.963
multi organism behavior GO:0051705 175 0.962
Fly
muscle organ development GO:0007517 127 0.962
eye morphogenesis GO:0048592 260 0.961
salivary gland morphogenesis GO:0007435 145 0.960
regulation of organ morphogenesis GO:2000027 78 0.960
Mouse
hematopoietic or lymphoid organ development GO:0048534 57 0.959
unidimensional cell growth GO:0009826 15 0.957
dorsal closure amnioserosa morphology change GO:0046664 7 0.956
determination of digestive tract left right asymmetry GO:0071907 6 0.954
digestive system development GO:0055123 149 0.953
regulation of multicellular organismal development GO:2000026 414 0.952
imaginal disc derived wing morphogenesis GO:0007476 337 0.951
heart process GO:0003015 37 0.951
nucleotide catabolic process GO:0009166 109 0.950
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.950
cellular response to organic substance GO:0071310 132 0.949
dorsal closure spreading of leading edge cells GO:0007395 4 0.944
memory GO:0007613 94 0.944
eye development GO:0001654 323 0.943
organic hydroxy compound metabolic process GO:1901615 83 0.939
cell maturation GO:0048469 144 0.939
Fly
appendage morphogenesis GO:0035107 397 0.938
guanosine containing compound metabolic process GO:1901068 74 0.937
positive regulation of lamellipodium organization GO:1902745 7 0.936
Human Mouse Fly
developmental growth involved in morphogenesis GO:0060560 65 0.935
organophosphate metabolic process GO:0019637 195 0.933
melanin metabolic process GO:0006582 47 0.933
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.932
response to biotic stimulus GO:0009607 294 0.932
Fly
small molecule metabolic process GO:0044281 305 0.930
exocrine system development GO:0035272 162 0.929
regulation of actin filament polymerization GO:0030833 25 0.928
Mouse Fly
circulatory system development GO:0072359 82 0.926
regulation of cell projection organization GO:0031344 92 0.926
embryonic hemopoiesis GO:0035162 26 0.925
response to metal ion GO:0010038 23 0.924
neuroblast division GO:0055057 35 0.923
Fly
pigment metabolic process GO:0042440 84 0.923
male mating behavior GO:0060179 70 0.923
regulation of anatomical structure size GO:0090066 163 0.919
Mouse Fly
cortical cytoskeleton organization GO:0030865 29 0.919
regulation of tube architecture open tracheal system GO:0035152 68 0.919
heterocycle catabolic process GO:0046700 166 0.915
enzyme linked receptor protein signaling pathway GO:0007167 179 0.911
gland morphogenesis GO:0022612 145 0.910
actin filament based process GO:0030029 220 0.909
hemocyte development GO:0007516 7 0.909
negative regulation of growth GO:0045926 84 0.909
hemopoiesis GO:0030097 46 0.905
embryonic organ development GO:0048568 50 0.905
establishment of tissue polarity GO:0007164 87 0.903
striated muscle cell development GO:0055002 50 0.903
positive regulation of cellular component organization GO:0051130 156 0.900
head involution GO:0008258 35 0.900
heart development GO:0007507 82 0.897
ribose phosphate metabolic process GO:0019693 145 0.896
regulation of protein metabolic process GO:0051246 256 0.894
erbb signaling pathway GO:0038127 58 0.884
morphogenesis of a polarized epithelium GO:0001738 93 0.883
respiratory system development GO:0060541 213 0.879
tracheal outgrowth open tracheal system GO:0007426 18 0.878
fusome organization GO:0045478 13 0.878
regulation of actin filament based process GO:0032970 42 0.877
Human Mouse Fly
maintenance of cell polarity GO:0030011 18 0.873
Fly
purine ribonucleoside metabolic process GO:0046128 127 0.872
regulation of catalytic activity GO:0050790 185 0.870
carbohydrate derivative metabolic process GO:1901135 217 0.868
intracellular signal transduction GO:0035556 300 0.868
compound eye photoreceptor development GO:0042051 78 0.866
regulation of hemocyte differentiation GO:0045610 22 0.863
learning or memory GO:0007611 141 0.862
oocyte anterior posterior axis specification GO:0007314 72 0.862
Fly
cellular component assembly involved in morphogenesis GO:0010927 151 0.860
carbohydrate derivative catabolic process GO:1901136 118 0.855
malpighian tubule development GO:0072002 64 0.853
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.851
Fly
negative regulation of developmental growth GO:0048640 64 0.847
cell division GO:0051301 248 0.847
Fly
axon choice point recognition GO:0016198 26 0.847
regulation of cell shape GO:0008360 113 0.846
actin filament bundle organization GO:0061572 28 0.845
cellular response to reactive oxygen species GO:0034614 14 0.844
endocytosis GO:0006897 310 0.843
positive regulation of locomotion GO:0040017 8 0.842
Human Zebrafish Mouse
metal ion homeostasis GO:0055065 44 0.840
imaginal disc derived appendage development GO:0048737 399 0.840
positive regulation of cell migration GO:0030335 2 0.838
Human Zebrafish Mouse
filopodium assembly GO:0046847 33 0.838
oocyte axis specification GO:0007309 108 0.833
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.831
Rat
stem cell division GO:0017145 69 0.831
Fly
regulation of tube size GO:0035150 46 0.818
spermatid differentiation GO:0048515 114 0.818
Fly
positive regulation of gene expression GO:0010628 290 0.818
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.814
Rat
nucleoside metabolic process GO:0009116 127 0.813
defense response GO:0006952 300 0.810
syncytium formation GO:0006949 43 0.801
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.801
photoreceptor cell development GO:0042461 96 0.797
regulation of secretion GO:0051046 44 0.796
gliogenesis GO:0042063 80 0.795
actin polymerization or depolymerization GO:0008154 31 0.795
Mouse Fly
secretion by cell GO:0032940 101 0.788
positive regulation of catalytic activity GO:0043085 118 0.786
stem cell proliferation GO:0072089 88 0.786
Fly
growth GO:0040007 359 0.783
organic acid metabolic process GO:0006082 103 0.780
germ band extension GO:0007377 11 0.780
specification of symmetry GO:0009799 13 0.774
digestive tract development GO:0048565 149 0.773
establishment of localization in cell GO:0051649 402 0.772
ion homeostasis GO:0050801 55 0.771
positive regulation of programmed cell death GO:0043068 62 0.769
synapse assembly GO:0007416 143 0.766
regulation of protein modification process GO:0031399 112 0.766
embryonic pattern specification GO:0009880 174 0.765
Fly
positive regulation of developmental process GO:0051094 143 0.764
Human Worm
regulation of actin cytoskeleton organization GO:0032956 42 0.761
Human Mouse Fly
regulation of locomotion GO:0040012 42 0.758
Human Zebrafish Mouse Worm
death GO:0016265 284 0.755
meiotic cell cycle GO:0051321 171 0.753
protein modification process GO:0036211 438 0.753
regulation of cell development GO:0060284 215 0.750
membrane organization GO:0061024 112 0.750
Mouse Worm
oocyte construction GO:0007308 112 0.748
Fly
regulation of apoptotic process GO:0042981 130 0.747
regulation of cellular protein metabolic process GO:0032268 243 0.747
cell type specific apoptotic process GO:0097285 38 0.739
positive regulation of actin filament polymerization GO:0030838 11 0.734
Mouse
neuromuscular junction development GO:0007528 149 0.731
Fly
epithelial cell cell adhesion GO:0090136 6 0.731
blastoderm segmentation GO:0007350 159 0.729
Fly
regulation of dendrite morphogenesis GO:0048814 28 0.727
single organism cell adhesion GO:0098602 47 0.725
Human Mouse
motor neuron axon guidance GO:0008045 58 0.724
protein localization GO:0008104 284 0.723
Mouse Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.721
imaginal disc derived wing hair organization GO:0035317 45 0.720
purine ribonucleoside catabolic process GO:0046130 112 0.717
regulation of dendrite development GO:0050773 37 0.715
regulation of axonogenesis GO:0050770 32 0.713
cell recognition GO:0008037 102 0.712
positive regulation of axon extension GO:0045773 2 0.710
gtp metabolic process GO:0046039 72 0.710
purine containing compound catabolic process GO:0072523 112 0.703
positive regulation of lamellipodium assembly GO:0010592 7 0.702
Human Mouse Fly
synaptic transmission GO:0007268 288 0.702
meiotic cell cycle process GO:1903046 132 0.693
ras protein signal transduction GO:0007265 88 0.691
Fly
purine nucleoside catabolic process GO:0006152 112 0.684
aggressive behavior GO:0002118 63 0.682
Fly
regulation of intracellular signal transduction GO:1902531 236 0.679
regulation of actin filament length GO:0030832 27 0.676
Mouse Fly
developmental maturation GO:0021700 172 0.675
Fly
dorsal closure elongation of leading edge cells GO:0007394 10 0.674
cellular protein localization GO:0034613 160 0.673
Mouse
regulation of programmed cell death GO:0043067 152 0.673
actin filament polymerization GO:0030041 27 0.670
Mouse Fly
epidermis development GO:0008544 65 0.663
larval development GO:0002164 104 0.655
Worm
regulation of lamellipodium assembly GO:0010591 15 0.652
epidermal cell differentiation GO:0009913 51 0.652
transcription from rna polymerase ii promoter GO:0006366 368 0.652
myofibril assembly GO:0030239 36 0.651
sex differentiation GO:0007548 81 0.650
Worm
genital disc development GO:0035215 44 0.649
carboxylic acid metabolic process GO:0019752 92 0.646
positive regulation of axonogenesis GO:0050772 2 0.646
single organism behavior GO:0044708 391 0.636
regulation of filopodium assembly GO:0051489 24 0.634
mating behavior GO:0007617 106 0.632
Fly
nucleoside phosphate metabolic process GO:0006753 162 0.632
embryonic ectodermal digestive tract development GO:0048611 4 0.631
multicellular organism growth GO:0035264 46 0.630
regulation of cell adhesion GO:0030155 27 0.625
Human
anterior midgut ectodermal morphogenesis GO:0007441 4 0.623
cellular response to hormone stimulus GO:0032870 44 0.620
actin cytoskeleton reorganization GO:0031532 22 0.618
catabolic process GO:0009056 409 0.617
cell migration involved in gastrulation GO:0042074 9 0.617
tripartite regional subdivision GO:0007351 103 0.617
Fly
determination of bilateral symmetry GO:0009855 13 0.615
gonad development GO:0008406 50 0.614
Worm
regulation of tube size open tracheal system GO:0035151 43 0.614
sensory organ morphogenesis GO:0090596 260 0.612
positive regulation of cell death GO:0010942 69 0.611
glial cell migration GO:0008347 31 0.610
regulation of heart morphogenesis GO:2000826 3 0.607
regulation of cellular component movement GO:0051270 42 0.606
Human Zebrafish Mouse Worm
glycosyl compound catabolic process GO:1901658 112 0.604
secondary metabolic process GO:0019748 75 0.603
heart morphogenesis GO:0003007 32 0.602
regulation of cell cell adhesion GO:0022407 21 0.595
purine nucleotide catabolic process GO:0006195 109 0.592
chromatin organization GO:0006325 207 0.591
segmentation GO:0035282 207 0.588
Fly
cardiac muscle tissue development GO:0048738 9 0.588
asymmetric neuroblast division GO:0055059 33 0.587
Fly
cardiovascular system development GO:0072358 82 0.580
single organism cellular localization GO:1902580 180 0.579
Mouse Fly
immune response GO:0006955 246 0.579
non sensory hair organization GO:0035316 47 0.577
epithelial tube morphogenesis GO:0060562 88 0.577
Fly
melanization defense response GO:0035006 45 0.576
positive regulation of cellular protein metabolic process GO:0032270 118 0.571
dendrite self avoidance GO:0070593 8 0.570
positive regulation of rna biosynthetic process GO:1902680 266 0.569
organonitrogen compound catabolic process GO:1901565 128 0.567
salivary gland development GO:0007431 162 0.565
regulation of neurogenesis GO:0050767 158 0.562
purine ribonucleotide metabolic process GO:0009150 145 0.559
positive regulation of growth GO:0045927 75 0.558
positive regulation of phosphorus metabolic process GO:0010562 139 0.557
regulation of actin polymerization or depolymerization GO:0008064 27 0.557
Mouse Fly
response to radiation GO:0009314 155 0.555
positive regulation of secretion by cell GO:1903532 20 0.548
response to inorganic substance GO:0010035 44 0.547
hindgut development GO:0061525 58 0.545
aging GO:0007568 143 0.544
chromatin silencing GO:0006342 76 0.543
actomyosin structure organization GO:0031032 56 0.543
Human
oxoacid metabolic process GO:0043436 103 0.541
positive regulation of apoptotic process GO:0043065 47 0.538
nucleotide metabolic process GO:0009117 161 0.538
regulation of secretion by cell GO:1903530 39 0.534
lamellipodium assembly GO:0030032 21 0.522
ribonucleoside metabolic process GO:0009119 127 0.521
lipid storage GO:0019915 38 0.520
Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.517
cell cell junction organization GO:0045216 55 0.516
regulation of cellular localization GO:0060341 136 0.516
apoptotic process GO:0006915 159 0.511
cellular macromolecule localization GO:0070727 220 0.507
Mouse Fly
regulation of hydrolase activity GO:0051336 97 0.506
tissue homeostasis GO:0001894 36 0.506
Rat
positive regulation of cellular catabolic process GO:0031331 95 0.503
muscle tissue development GO:0060537 30 0.498
regulation of neuron differentiation GO:0045664 103 0.497
gland development GO:0048732 191 0.496
compound eye photoreceptor cell differentiation GO:0001751 140 0.495
g protein coupled receptor signaling pathway GO:0007186 136 0.488
Mouse
regulation of cell migration GO:0030334 22 0.487
Human Zebrafish Mouse Worm
cellular catabolic process GO:0044248 372 0.486
muscle cell development GO:0055001 50 0.486
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.483
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.481
regulation of lamellipodium organization GO:1902743 15 0.481
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.477
Human
apoptotic cell clearance GO:0043277 14 0.476
Mouse Worm
phosphorylation GO:0016310 294 0.475
response to bacterium GO:0009617 198 0.473
Fly
actin filament organization GO:0007015 126 0.473
immune system development GO:0002520 57 0.472
positive regulation of nucleic acid templated transcription GO:1903508 266 0.471
single organism catabolic process GO:0044712 228 0.469
organic substance catabolic process GO:1901575 308 0.468
proteolysis GO:0006508 192 0.466
cellular ion homeostasis GO:0006873 39 0.466
pole plasm oskar mrna localization GO:0045451 46 0.464
Fly
compound eye retinal cell programmed cell death GO:0046667 23 0.464
locomotory behavior GO:0007626 176 0.463
cellular response to chemical stimulus GO:0070887 199 0.459
Human Mouse Rat
regulation of cytoskeleton organization GO:0051493 89 0.459
Human Mouse Fly
cellular protein modification process GO:0006464 438 0.459
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.451
establishment of ommatidial planar polarity GO:0042067 49 0.451
Fly
endodermal cell differentiation GO:0035987 3 0.449
programmed cell death GO:0012501 257 0.449
purine nucleoside metabolic process GO:0042278 127 0.447
hemocyte migration GO:0035099 19 0.439
female sex differentiation GO:0046660 20 0.438
dna replication GO:0006260 48 0.438
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.436
eye photoreceptor cell differentiation GO:0001754 145 0.436
single organism intracellular transport GO:1902582 207 0.430
neuronal stem cell division GO:0036445 35 0.428
Fly
positive regulation of cell proliferation GO:0008284 47 0.426
Mouse
ovarian nurse cell to oocyte transport GO:0007300 27 0.425
lipid localization GO:0010876 54 0.424
Fly
positive regulation of endopeptidase activity GO:0010950 26 0.423
muscle system process GO:0003012 21 0.422
response to starvation GO:0042594 97 0.419
response to transforming growth factor beta GO:0071559 18 0.419
establishment of protein localization GO:0045184 163 0.416
dorsal ventral axon guidance GO:0033563 2 0.409
Worm
purine nucleoside triphosphate catabolic process GO:0009146 108 0.406
collateral sprouting GO:0048668 3 0.405
protein transport GO:0015031 155 0.404
neuron maturation GO:0042551 31 0.398
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.395
multicellular organismal reproductive behavior GO:0033057 110 0.391
regulation of response to wounding GO:1903034 19 0.390
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.386
Rat
muscle fiber development GO:0048747 12 0.384
germ band shortening GO:0007390 19 0.382
positive regulation of wound healing GO:0090303 12 0.382
innate immune response GO:0045087 144 0.382
axonal fasciculation GO:0007413 12 0.380
renal tubule development GO:0061326 64 0.378
single organism membrane organization GO:0044802 93 0.378
Mouse
positive regulation of cell growth GO:0030307 19 0.377
regulation of protein kinase activity GO:0045859 51 0.377
embryonic hindgut morphogenesis GO:0048619 48 0.371
cation homeostasis GO:0055080 51 0.371
response to wounding GO:0009611 94 0.371
positive regulation of protein localization to plasma membrane GO:1903078 3 0.367
negative regulation of signaling GO:0023057 219 0.365
positive regulation of peptidase activity GO:0010952 29 0.365
axon regeneration GO:0031103 8 0.362
Worm
regulation of mitotic cell cycle GO:0007346 190 0.361
cell cycle phase transition GO:0044770 140 0.359
neuron projection extension GO:1990138 32 0.358
regulation of cellular catabolic process GO:0031329 157 0.358
multi multicellular organism process GO:0044706 123 0.356
negative regulation of signal transduction GO:0009968 206 0.355
positive regulation of cell differentiation GO:0045597 64 0.350
Human
extracellular structure organization GO:0043062 46 0.350
regulation of retinal cell programmed cell death GO:0046668 18 0.349
response to temperature stimulus GO:0009266 106 0.347
calcium ion homeostasis GO:0055074 23 0.346
synapse organization GO:0050808 196 0.346
cellular response to growth factor stimulus GO:0071363 30 0.346
positive regulation of cell development GO:0010720 61 0.346
Human
protein complex biogenesis GO:0070271 201 0.344
Mouse Fly
regulation of multi organism process GO:0043900 131 0.342
mitotic cell cycle phase transition GO:0044772 138 0.341
positive regulation of hydrolase activity GO:0051345 78 0.340
organic substance transport GO:0071702 257 0.337
compound eye photoreceptor fate commitment GO:0001752 36 0.337
regulation of cell proliferation GO:0042127 163 0.334
Mouse
brain development GO:0007420 120 0.332
Mouse
pole plasm rna localization GO:0007316 52 0.327
Fly
positive regulation of secretion GO:0051047 22 0.327
regulation of wound healing GO:0061041 13 0.327
adherens junction organization GO:0034332 27 0.325
formation of anatomical boundary GO:0048859 37 0.323
ribonucleotide metabolic process GO:0009259 145 0.322
organophosphate catabolic process GO:0046434 112 0.321
small gtpase mediated signal transduction GO:0007264 88 0.318
Mouse Worm Fly
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.313
response to toxic substance GO:0009636 22 0.313
ribonucleoside catabolic process GO:0042454 112 0.313
embryonic axis specification GO:0000578 107 0.313
Fly
ribonucleoside triphosphate metabolic process GO:0009199 119 0.312
organelle localization GO:0051640 148 0.310
axis specification GO:0009798 167 0.309
Fly
male genitalia development GO:0030539 19 0.305
cell junction assembly GO:0034329 42 0.304
Human
aromatic compound catabolic process GO:0019439 166 0.301
meiotic chromosome segregation GO:0045132 59 0.300
cytoplasm organization GO:0007028 64 0.299
Fly
exocytosis GO:0006887 28 0.298
response to insulin GO:0032868 29 0.296
chromosome organization GO:0051276 360 0.294
actin filament bundle assembly GO:0051017 26 0.289
peptidyl amino acid modification GO:0018193 105 0.289
adherens junction maintenance GO:0034334 9 0.288
genitalia morphogenesis GO:0035112 16 0.288
single organismal cell cell adhesion GO:0016337 45 0.286
Human
positive regulation of protein kinase activity GO:0045860 25 0.285
purine containing compound metabolic process GO:0072521 155 0.285
asymmetric stem cell division GO:0098722 49 0.284
Fly
positive regulation of phosphate metabolic process GO:0045937 139 0.282
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.278
Rat
cellular nitrogen compound catabolic process GO:0044270 165 0.277
positive regulation of neuron differentiation GO:0045666 26 0.273
intracellular transport GO:0046907 228 0.270
epithelial cell migration open tracheal system GO:0007427 32 0.270
hindgut morphogenesis GO:0007442 58 0.269
reproductive structure development GO:0048608 74 0.269
Worm
substrate dependent cell migration GO:0006929 3 0.268
developmental programmed cell death GO:0010623 138 0.267
ovarian fusome organization GO:0030723 11 0.266
cell proliferation GO:0008283 299 0.266
purine ribonucleotide catabolic process GO:0009154 109 0.265
anterior posterior axis specification embryo GO:0008595 103 0.263
Fly
cellular amino acid metabolic process GO:0006520 61 0.263
anterior posterior axis specification GO:0009948 109 0.263
Fly
apoptotic process involved in development GO:1902742 20 0.262
cell cell signaling involved in cell fate commitment GO:0045168 210 0.260
Fly
endomembrane system organization GO:0010256 119 0.260
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.258
renal tubule morphogenesis GO:0061333 44 0.258
establishment of spindle orientation GO:0051294 18 0.256
response to heat GO:0009408 63 0.253
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.252
Fly
glycosyl compound metabolic process GO:1901657 127 0.248
ribonucleoside triphosphate catabolic process GO:0009203 108 0.247
positive regulation of cytoskeleton organization GO:0051495 21 0.245
Human Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.244
response to peptide hormone GO:0043434 29 0.243
positive regulation of organelle organization GO:0010638 65 0.243
Human Mouse
micropyle formation GO:0046844 4 0.243
response to oxidative stress GO:0006979 86 0.241
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.238
regulation of neuron death GO:1901214 26 0.238
anterior posterior pattern specification GO:0009952 136 0.235
Fly
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.234
nucleoside phosphate catabolic process GO:1901292 110 0.232
response to growth factor GO:0070848 31 0.232
reproductive system development GO:0061458 74 0.226
Worm
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.221
Fly
body morphogenesis GO:0010171 2 0.221
Worm
regulation of organelle organization GO:0033043 196 0.219
Human Mouse Fly

Rac1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.353