Drosophila melanogaster

136 known processes

ik2 (Dmel_CG2615)

IkappaB kinase-like 2

(Aliases: IK2,Ik2/DmIKK,dIKK,l(2)38Ea,DmIKKepsilon,Dmel\CG2615,Dmik2,IKKepsilon,DmIKKepsilon/dIK2,APTX7,38D.31,CG2615,Ik2,IKK,dik2,Dik2,DIK2)

ik2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendrite development GO:0016358 204 1.000
dendrite morphogenesis GO:0048813 199 0.994
cell migration GO:0016477 238 0.991
epithelial cell migration GO:0010631 148 0.977
regulation of multicellular organismal development GO:2000026 414 0.969
cell maturation GO:0048469 144 0.949
ovarian follicle cell development GO:0030707 248 0.939
regulation of nervous system development GO:0051960 248 0.927
neuromuscular junction development GO:0007528 149 0.923
immune system process GO:0002376 347 0.923
Mouse Fly
response to other organism GO:0051707 293 0.920
Mouse Fly
small molecule metabolic process GO:0044281 305 0.890
axonogenesis GO:0007409 290 0.889
regulation of cell differentiation GO:0045595 302 0.882
columnar cuboidal epithelial cell development GO:0002066 249 0.873
purine ribonucleotide metabolic process GO:0009150 145 0.873
ribose phosphate metabolic process GO:0019693 145 0.864
regulation of neurogenesis GO:0050767 158 0.858
chorion containing eggshell formation GO:0007304 105 0.855
axon development GO:0061564 297 0.847
immune response GO:0006955 246 0.839
Mouse Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.827
regulation of cell morphogenesis GO:0022604 163 0.826
negative regulation of developmental process GO:0051093 201 0.813
cell motility GO:0048870 251 0.806
regulation of cell development GO:0060284 215 0.796
organophosphate metabolic process GO:0019637 195 0.783
epithelial cell development GO:0002064 274 0.776
eye morphogenesis GO:0048592 260 0.756
organonitrogen compound metabolic process GO:1901564 318 0.751
Fly
neuron maturation GO:0042551 31 0.748
chemotaxis GO:0006935 249 0.738
ribonucleotide catabolic process GO:0009261 109 0.716
purine nucleoside triphosphate metabolic process GO:0009144 119 0.701
male gamete generation GO:0048232 201 0.699
neuron projection guidance GO:0097485 241 0.696
ovarian follicle cell migration GO:0007297 121 0.672
ribonucleoside triphosphate metabolic process GO:0009199 119 0.662
compound eye development GO:0048749 307 0.641
actin filament based process GO:0030029 220 0.630
gland development GO:0048732 191 0.626
response to bacterium GO:0009617 198 0.625
Mouse Fly
regulation of programmed cell death GO:0043067 152 0.622
sensory organ morphogenesis GO:0090596 260 0.610
axon guidance GO:0007411 233 0.589
epithelium migration GO:0090132 148 0.583
branching involved in open tracheal system development GO:0060446 45 0.569
negative regulation of cell development GO:0010721 62 0.565
compound eye morphogenesis GO:0001745 249 0.530
regulation of cellular component biogenesis GO:0044087 201 0.527
embryo development ending in birth or egg hatching GO:0009792 152 0.524
purine nucleoside metabolic process GO:0042278 127 0.520
synapse assembly GO:0007416 143 0.515
death GO:0016265 284 0.514
purine ribonucleoside metabolic process GO:0046128 127 0.511
regulation of response to stress GO:0080134 200 0.507
Mouse Fly
organic acid metabolic process GO:0006082 103 0.492
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.483
nucleoside phosphate catabolic process GO:1901292 110 0.478
endocytosis GO:0006897 310 0.469
tissue morphogenesis GO:0048729 297 0.450
purine nucleoside triphosphate catabolic process GO:0009146 108 0.447
negative regulation of neuroblast proliferation GO:0007406 27 0.440
gastrulation involving germ band extension GO:0010004 36 0.434
synaptic growth at neuromuscular junction GO:0051124 119 0.433
nucleoside metabolic process GO:0009116 127 0.425
regulation of localization GO:0032879 275 0.421
regulation of immune system process GO:0002682 176 0.420
Mouse Fly
carbohydrate derivative catabolic process GO:1901136 118 0.410
neuron remodeling GO:0016322 29 0.408
branching morphogenesis of an epithelial tube GO:0048754 45 0.406
positive regulation of macromolecule metabolic process GO:0010604 405 0.404
ameboidal type cell migration GO:0001667 151 0.398
border follicle cell migration GO:0007298 113 0.394
epithelial cell differentiation GO:0030855 322 0.392
regulation of cell cycle phase transition GO:1901987 130 0.383
localization of cell GO:0051674 257 0.383
regulation of cell cycle GO:0051726 291 0.379
positive regulation of molecular function GO:0044093 136 0.378
response to external biotic stimulus GO:0043207 293 0.371
Mouse Fly
ribonucleoside metabolic process GO:0009119 127 0.362
positive regulation of cell development GO:0010720 61 0.354
regulation of synapse organization GO:0050807 110 0.350
programmed cell death GO:0012501 257 0.346
developmental programmed cell death GO:0010623 138 0.346
nucleobase containing small molecule metabolic process GO:0055086 174 0.342
taxis GO:0042330 304 0.330
vesicle mediated transport GO:0016192 381 0.322
digestive tract morphogenesis GO:0048546 127 0.321
mitotic cell cycle phase transition GO:0044772 138 0.314
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.308
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.303
Human Fly
regulation of molecular function GO:0065009 217 0.302
salivary gland morphogenesis GO:0007435 145 0.294
lateral inhibition GO:0046331 206 0.294
mesenchymal cell differentiation GO:0048762 1 0.292
synapse organization GO:0050808 196 0.289
developmental growth GO:0048589 280 0.289
dna repair GO:0006281 54 0.275
regulation of cytoskeleton organization GO:0051493 89 0.268
regulation of apoptotic process GO:0042981 130 0.265
regulation of catabolic process GO:0009894 170 0.264
exocrine system development GO:0035272 162 0.263
ribonucleoside triphosphate catabolic process GO:0009203 108 0.260
regulation of embryonic development GO:0045995 68 0.251
negative regulation of programmed cell death GO:0043069 72 0.249
nucleoside phosphate metabolic process GO:0006753 162 0.247
central nervous system development GO:0007417 201 0.246
cell type specific apoptotic process GO:0097285 38 0.245
regulation of cellular catabolic process GO:0031329 157 0.236
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.230
ribonucleoside catabolic process GO:0042454 112 0.228
innate immune response GO:0045087 144 0.227
Mouse Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.227
purine nucleotide catabolic process GO:0006195 109 0.217
jak stat cascade GO:0007259 49 0.216
regulation of cell cycle process GO:0010564 181 0.212
nucleotide metabolic process GO:0009117 161 0.211
cellular nitrogen compound catabolic process GO:0044270 165 0.208
negative regulation of nervous system development GO:0051961 92 0.206
carbohydrate derivative metabolic process GO:1901135 217 0.202
regulation of synapse assembly GO:0051963 94 0.202
regulation of dendrite morphogenesis GO:0048814 28 0.199
dna metabolic process GO:0006259 227 0.197
aromatic compound catabolic process GO:0019439 166 0.193
purine containing compound metabolic process GO:0072521 155 0.192
hematopoietic or lymphoid organ development GO:0048534 57 0.191
nucleoside triphosphate catabolic process GO:0009143 108 0.189
glycosyl compound catabolic process GO:1901658 112 0.186
spermatogenesis GO:0007283 200 0.184
morphogenesis of a branching epithelium GO:0061138 45 0.183
glycosyl compound metabolic process GO:1901657 127 0.180
gastrulation with mouth forming first GO:0001703 36 0.174
regulation of cellular response to stress GO:0080135 89 0.172
negative regulation of cell differentiation GO:0045596 143 0.170
chromosome organization GO:0051276 360 0.170
cell cell signaling involved in cell fate commitment GO:0045168 210 0.169
actin filament bundle organization GO:0061572 28 0.166
regulation of immune response GO:0050776 118 0.166
Mouse Fly
axis specification GO:0009798 167 0.164
eggshell chorion assembly GO:0007306 66 0.163
cellular response to dna damage stimulus GO:0006974 223 0.160
Human
eye photoreceptor cell development GO:0042462 81 0.159
protein complex biogenesis GO:0070271 201 0.155
negative regulation of cell communication GO:0010648 223 0.155
cell cycle phase transition GO:0044770 140 0.153
negative regulation of neurogenesis GO:0050768 53 0.152
regulation of axonogenesis GO:0050770 32 0.152
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.151
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.149
digestive tract development GO:0048565 149 0.149
cell death GO:0008219 279 0.148
regulation of cell proliferation GO:0042127 163 0.145
defense response to bacterium GO:0042742 178 0.145
Mouse Fly
gastrulation GO:0007369 70 0.144
cellular protein localization GO:0034613 160 0.144
negative regulation of apoptotic process GO:0043066 63 0.144
apoptotic process GO:0006915 159 0.139
purine nucleoside catabolic process GO:0006152 112 0.137
protein localization GO:0008104 284 0.136
regulation of mitotic cell cycle GO:0007346 190 0.135
digestive system development GO:0055123 149 0.135
muscle organ development GO:0007517 127 0.134
response to biotic stimulus GO:0009607 294 0.134
Mouse Fly
purine containing compound catabolic process GO:0072523 112 0.132
chaeta development GO:0022416 97 0.132
developmental maturation GO:0021700 172 0.131
dorsal appendage formation GO:0046843 47 0.130
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.129
Human
regulation of gliogenesis GO:0014013 11 0.128
regulation of cell death GO:0010941 173 0.127
embryonic morphogenesis GO:0048598 206 0.127
purine ribonucleotide catabolic process GO:0009154 109 0.124
defense response GO:0006952 300 0.123
Mouse Fly
actin cytoskeleton organization GO:0030036 206 0.122
cellular response to extracellular stimulus GO:0031668 64 0.122
positive regulation of developmental process GO:0051094 143 0.120
regulation of growth GO:0040008 233 0.118
larval development GO:0002164 104 0.118
negative regulation of cell cycle GO:0045786 116 0.116
syncytium formation GO:0006949 43 0.116
phosphorylation GO:0016310 294 0.113
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.113
Human
peptidyl tyrosine phosphorylation GO:0018108 24 0.113
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.111
Human
dorsal closure GO:0007391 79 0.111
gland morphogenesis GO:0022612 145 0.110
macromolecular complex assembly GO:0065003 256 0.109
defense response to other organism GO:0098542 225 0.109
Mouse Fly
salivary gland development GO:0007431 162 0.105
cell growth GO:0016049 108 0.104
cellular component assembly involved in morphogenesis GO:0010927 151 0.101
negative regulation of cellular component organization GO:0051129 108 0.100
regulation of innate immune response GO:0045088 71 0.100
Mouse Fly
endomembrane system organization GO:0010256 119 0.096
phagocytosis GO:0006909 215 0.095
regulation of gene expression epigenetic GO:0040029 128 0.095
anterior posterior axis specification embryo GO:0008595 103 0.093
neuroblast proliferation GO:0007405 74 0.093
organic cyclic compound catabolic process GO:1901361 168 0.091
regulation of stem cell proliferation GO:0072091 40 0.090
meiosis i GO:0007127 59 0.090
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.089
regulation of compound eye cone cell fate specification GO:0042682 4 0.089
negative regulation of cell death GO:0060548 81 0.088
mitotic spindle organization GO:0007052 220 0.088
gliogenesis GO:0042063 80 0.088
regulation of cellular localization GO:0060341 136 0.087
regulation of vesicle mediated transport GO:0060627 59 0.086
single organism catabolic process GO:0044712 228 0.086
antimicrobial humoral response GO:0019730 99 0.084
Fly
regulation of proteolysis GO:0030162 87 0.084
positive regulation of rna biosynthetic process GO:1902680 266 0.083
Human
intracellular signal transduction GO:0035556 300 0.083
Human Mouse
dorsal ventral axis specification GO:0009950 66 0.082
regulation of transport GO:0051049 181 0.081
regulation of neuron projection development GO:0010975 69 0.081
eye development GO:0001654 323 0.080
regulation of cellular protein metabolic process GO:0032268 243 0.080
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.076
peripheral nervous system neuron differentiation GO:0048934 8 0.076
dna recombination GO:0006310 32 0.076
compound eye photoreceptor cell differentiation GO:0001751 140 0.075
protein complex assembly GO:0006461 200 0.075
regulation of cellular amine metabolic process GO:0033238 3 0.074
embryonic development via the syncytial blastoderm GO:0001700 148 0.074
telencephalon development GO:0021537 2 0.074
negative regulation of mitotic cell cycle GO:0045930 109 0.074
positive regulation of phagocytosis engulfment GO:0060100 1 0.073
imaginal disc fusion GO:0046528 19 0.073
tracheal outgrowth open tracheal system GO:0007426 18 0.070
oocyte axis specification GO:0007309 108 0.069
nucleobase containing compound catabolic process GO:0034655 165 0.069
negative regulation of cell cycle process GO:0010948 109 0.068
morphogenesis of a branching structure GO:0001763 45 0.068
regulation of embryonic cell shape GO:0016476 30 0.068
carboxylic acid metabolic process GO:0019752 92 0.067
cellular macromolecule localization GO:0070727 220 0.067
anterior posterior pattern specification GO:0009952 136 0.067
cell cycle checkpoint GO:0000075 95 0.066
regulation of glial cell proliferation GO:0060251 11 0.066
purine nucleotide metabolic process GO:0006163 146 0.065
regulation of catalytic activity GO:0050790 185 0.065
organophosphate catabolic process GO:0046434 112 0.065
actin filament organization GO:0007015 126 0.065
regionalization GO:0003002 416 0.063
nucleotide catabolic process GO:0009166 109 0.063
protein polymerization GO:0051258 42 0.061
apical constriction GO:0003383 18 0.060
tube development GO:0035295 244 0.060
camera type eye development GO:0043010 4 0.060
organonitrogen compound catabolic process GO:1901565 128 0.060
proteolysis GO:0006508 192 0.060
cellular response to chemical stimulus GO:0070887 199 0.060
stem cell proliferation GO:0072089 88 0.060
morphogenesis of embryonic epithelium GO:0016331 94 0.059
immune system development GO:0002520 57 0.059
positive regulation of catabolic process GO:0009896 105 0.059
protein targeting to nucleus GO:0044744 51 0.059
skeletal muscle organ development GO:0060538 48 0.058
eye photoreceptor cell differentiation GO:0001754 145 0.058
regulation of cellular amino acid metabolic process GO:0006521 0 0.058
regulation of mitotic cell cycle phase transition GO:1901990 130 0.058
protein modification process GO:0036211 438 0.057
positive regulation of catalytic activity GO:0043085 118 0.056
rhabdomere development GO:0042052 38 0.056
guanosine containing compound catabolic process GO:1901069 74 0.056
cellular amino acid metabolic process GO:0006520 61 0.055
negative regulation of multicellular organismal process GO:0051241 142 0.054
body morphogenesis GO:0010171 2 0.054
spermatid differentiation GO:0048515 114 0.054
homeostatic process GO:0042592 199 0.054
humoral immune response GO:0006959 117 0.054
Fly
receptor mediated endocytosis GO:0006898 21 0.053
response to transforming growth factor beta GO:0071559 18 0.053
epithelial cell migration open tracheal system GO:0007427 32 0.053
tube morphogenesis GO:0035239 191 0.052
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.051
respiratory system development GO:0060541 213 0.051
response to abiotic stimulus GO:0009628 341 0.051
detection of stimulus GO:0051606 156 0.051
eggshell formation GO:0030703 105 0.051
amine metabolic process GO:0009308 12 0.050
regulation of actin filament length GO:0030832 27 0.049
oxoacid metabolic process GO:0043436 103 0.049
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.049
tissue death GO:0016271 102 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.048
limb development GO:0060173 1 0.047
histolysis GO:0007559 102 0.046
morphogenesis of an epithelium GO:0002009 276 0.046
regulation of execution phase of apoptosis GO:1900117 5 0.045
cellular ketone metabolic process GO:0042180 24 0.045
positive regulation of rna metabolic process GO:0051254 271 0.045
Human
developmental growth involved in morphogenesis GO:0060560 65 0.045
dna methylation or demethylation GO:0044728 4 0.045
regulation of retinal cell programmed cell death GO:0046668 18 0.044
tripartite regional subdivision GO:0007351 103 0.044
mitotic dna damage checkpoint GO:0044773 74 0.044
meiotic cell cycle process GO:1903046 132 0.043
positive regulation of cellular component biogenesis GO:0044089 80 0.043
mitotic cell cycle checkpoint GO:0007093 88 0.043
salivary gland cell autophagic cell death GO:0035071 83 0.043
protein palmitoylation GO:0018345 2 0.042
heterocycle catabolic process GO:0046700 166 0.042
regulation of cellular component size GO:0032535 98 0.041
organic substance transport GO:0071702 257 0.041
regulation of cell projection organization GO:0031344 92 0.040
golgi organization GO:0007030 66 0.040
germarium derived female germ line cyst encapsulation GO:0030708 8 0.040
lipid localization GO:0010876 54 0.039
purine ribonucleoside catabolic process GO:0046130 112 0.039
cytoplasmic transport GO:0016482 130 0.039
negative regulation of gene expression GO:0010629 387 0.039
Mouse
cell activation GO:0001775 9 0.039
Mouse
positive regulation of immune response GO:0050778 63 0.039
Mouse Fly
tricarboxylic acid metabolic process GO:0072350 1 0.039
growth GO:0040007 359 0.039
cell fate determination GO:0001709 91 0.038
gtp metabolic process GO:0046039 72 0.038
regulation of intracellular signal transduction GO:1902531 236 0.038
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.038
terminal branching open tracheal system GO:0007430 17 0.037
compound eye photoreceptor development GO:0042051 78 0.037
ribonucleotide metabolic process GO:0009259 145 0.037
regulation of neuron differentiation GO:0045664 103 0.036
response to lipopolysaccharide GO:0032496 4 0.036
head involution GO:0008258 35 0.036
regulation of rho protein signal transduction GO:0035023 20 0.036
tissue migration GO:0090130 155 0.036
regulation of cell shape GO:0008360 113 0.036
catabolic process GO:0009056 409 0.035
Fly
epithelial tube morphogenesis GO:0060562 88 0.035
nucleoside catabolic process GO:0009164 112 0.035
nuclear import GO:0051170 51 0.035
oocyte construction GO:0007308 112 0.035
positive regulation of intracellular signal transduction GO:1902533 116 0.035
Human
chaeta morphogenesis GO:0008407 42 0.035
regulation of actin filament polymerization GO:0030833 25 0.035
wound healing GO:0042060 75 0.034
inter male aggressive behavior GO:0002121 60 0.034
regulation of dendrite development GO:0050773 37 0.034
regulation of actin polymerization or depolymerization GO:0008064 27 0.034
response to decreased oxygen levels GO:0036293 58 0.034
gene silencing GO:0016458 138 0.033
cellular catabolic process GO:0044248 372 0.033
photoreceptor cell development GO:0042461 96 0.032
dna replication GO:0006260 48 0.032
secretion by cell GO:0032940 101 0.032
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.032
positive regulation of transcription dna templated GO:0045893 266 0.032
Human
organic substance catabolic process GO:1901575 308 0.032
Fly
photoreceptor cell differentiation GO:0046530 170 0.032
embryonic axis specification GO:0000578 107 0.031
purine nucleoside monophosphate catabolic process GO:0009128 38 0.031
cellular macromolecular complex assembly GO:0034622 153 0.031
cellular amine metabolic process GO:0044106 12 0.031
regulation of cell size GO:0008361 63 0.031
regulation of protein metabolic process GO:0051246 256 0.031
chromatin organization GO:0006325 207 0.031
positive regulation of signal transduction GO:0009967 223 0.030
Human
organelle localization GO:0051640 148 0.030
protein catabolic process GO:0030163 101 0.029
Fly
regulation of neuroblast proliferation GO:1902692 34 0.029
positive regulation of cellular component organization GO:0051130 156 0.029
positive regulation of proteolysis GO:0045862 52 0.029
germarium derived egg chamber formation GO:0007293 101 0.029
cell recognition GO:0008037 102 0.029
phagocytosis engulfment GO:0006911 11 0.029
regulation of anatomical structure size GO:0090066 163 0.029
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
Human
spermatid development GO:0007286 98 0.028
cell division GO:0051301 248 0.028
protein localization to nucleus GO:0034504 55 0.028
forebrain development GO:0030900 2 0.028
positive regulation of immune system process GO:0002684 68 0.027
Mouse Fly
positive regulation of cell migration GO:0030335 2 0.027
apoptotic signaling pathway GO:0097190 27 0.027
Human
cortical actin cytoskeleton organization GO:0030866 24 0.027
regulation of chromosome organization GO:0033044 64 0.026
negative regulation of stem cell proliferation GO:2000647 30 0.026
regulation of cell cycle g1 s phase transition GO:1902806 23 0.026
r7 cell differentiation GO:0045466 43 0.026
initiation of dorsal closure GO:0007392 12 0.026
embryonic digestive tract development GO:0048566 5 0.025
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.025
embryonic pattern specification GO:0009880 174 0.025
purine nucleoside monophosphate metabolic process GO:0009126 50 0.025
regulation of neural precursor cell proliferation GO:2000177 35 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
protein import into nucleus GO:0006606 51 0.025
brain development GO:0007420 120 0.024
hemocyte development GO:0007516 7 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
locomotory behavior GO:0007626 176 0.024
embryonic digestive tract morphogenesis GO:0048557 4 0.023
oocyte microtubule cytoskeleton organization GO:0016325 35 0.023
cortical cytoskeleton organization GO:0030865 29 0.023
developmental cell growth GO:0048588 52 0.023
regulation of synapse structure and activity GO:0050803 128 0.023
execution phase of apoptosis GO:0097194 7 0.023
regulation of actin filament based process GO:0032970 42 0.023
regulation of organ morphogenesis GO:2000027 78 0.023
positive regulation of multicellular organismal process GO:0051240 143 0.023
Human Mouse
muscle cell differentiation GO:0042692 103 0.022
sex differentiation GO:0007548 81 0.022
regulation of response to external stimulus GO:0032101 115 0.022
Fly
response to wounding GO:0009611 94 0.022
ion transport GO:0006811 145 0.022
muscle structure development GO:0061061 224 0.022
dna biosynthetic process GO:0071897 24 0.021
actin filament bundle assembly GO:0051017 26 0.021
response to ionizing radiation GO:0010212 32 0.021
positive regulation of cellular protein metabolic process GO:0032270 118 0.021
segmentation GO:0035282 207 0.021
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.020
cellular protein modification process GO:0006464 438 0.020
regulation of jak stat cascade GO:0046425 43 0.020
retinal cone cell differentiation GO:0042670 2 0.020
regulation of cell motility GO:2000145 23 0.020
gtp catabolic process GO:0006184 72 0.020
regulation of protein acetylation GO:1901983 7 0.020
establishment of protein localization GO:0045184 163 0.020
negative regulation of cell proliferation GO:0008285 69 0.020
organelle assembly GO:0070925 198 0.020
positive regulation of cell communication GO:0010647 250 0.020
Human
cellular protein complex assembly GO:0043623 71 0.020
positive regulation of dendrite morphogenesis GO:0050775 9 0.020
regulation of phosphate metabolic process GO:0019220 210 0.019
regulation of response to dna damage stimulus GO:2001020 23 0.019
chemical homeostasis GO:0048878 92 0.019
actin polymerization or depolymerization GO:0008154 31 0.019
dorsal ventral pattern formation GO:0009953 133 0.019
cellular response to organic substance GO:0071310 132 0.019
apical constriction involved in gastrulation GO:0003384 7 0.019
positive regulation of cell differentiation GO:0045597 64 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
Human Mouse Fly
regulation of axon extension GO:0030516 8 0.019
chromosome segregation GO:0007059 157 0.019
regulation of developmental growth GO:0048638 174 0.019
positive regulation of organelle organization GO:0010638 65 0.018
single organism nuclear import GO:1902593 51 0.018
regulation of protein localization GO:0032880 76 0.018
salivary gland histolysis GO:0035070 88 0.018
muscle attachment GO:0016203 36 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
g1 s transition of mitotic cell cycle GO:0000082 31 0.018
cellular homeostasis GO:0019725 80 0.018
regulation of protein polymerization GO:0032271 28 0.018
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.018
asymmetric cell division GO:0008356 37 0.018
regulation of multi organism process GO:0043900 131 0.018
Fly
epithelial cell morphogenesis GO:0003382 25 0.018
pupariation GO:0035073 14 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
retina development in camera type eye GO:0060041 4 0.017
mitotic cell cycle embryonic GO:0045448 38 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
glial cell differentiation GO:0010001 35 0.017
regulation of peptidyl lysine acetylation GO:2000756 7 0.017
meiotic nuclear division GO:0007126 151 0.017
gonad development GO:0008406 50 0.017
response to hypoxia GO:0001666 53 0.017
mesenchymal cell development GO:0014031 1 0.017
regulation of cysteine type endopeptidase activity GO:2000116 27 0.017
positive regulation of actin filament polymerization GO:0030838 11 0.017
actin filament polymerization GO:0030041 27 0.017
posttranscriptional gene silencing GO:0016441 46 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
Human Mouse Fly
regulation of locomotion GO:0040012 42 0.016
positive regulation of synapse assembly GO:0051965 29 0.016
protein acylation GO:0043543 42 0.016
establishment of protein localization to organelle GO:0072594 62 0.016
centrosome duplication GO:0051298 121 0.016
blastoderm segmentation GO:0007350 159 0.016
regulation of phosphatase activity GO:0010921 3 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
peripheral nervous system neuron development GO:0048935 8 0.016
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.016
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.015
regulation of secretion by cell GO:1903530 39 0.015
positive regulation of protein complex assembly GO:0031334 22 0.015
regulation of organelle organization GO:0033043 196 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
mesodermal cell migration GO:0008078 7 0.015
hematopoietic progenitor cell differentiation GO:0002244 1 0.015
actomyosin structure organization GO:0031032 56 0.015
cell proliferation GO:0008283 299 0.015
Mouse
unidimensional cell growth GO:0009826 15 0.015
stem cell development GO:0048864 79 0.015
syncytium formation by plasma membrane fusion GO:0000768 43 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
protein transport GO:0015031 155 0.015
atp metabolic process GO:0046034 49 0.015
muscle cell development GO:0055001 50 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
Fly
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.015
regulation of protein transport GO:0051223 57 0.015
chromatin silencing GO:0006342 76 0.015
meiotic cytokinesis GO:0033206 33 0.014

ik2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org