Drosophila melanogaster

225 known processes

Rala (Dmel_CG2849)

Ras-related protein

(Aliases: l(1)G0501,anon-EST:fe1H4,Drala,DralA,Ral-a,D-RalA,Ral,dRal,ralA,l(1)G0373,ral,Dm RalA,CG2849,Dmel\CG2849,RalA,DRala,DRal,Dral,RALA,l(1)G0174)

Rala biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ovarian follicle cell migration GO:0007297 121 1.000
epithelial cell differentiation GO:0030855 322 1.000
epithelial cell migration GO:0010631 148 1.000
border follicle cell migration GO:0007298 113 1.000
columnar cuboidal epithelial cell differentiation GO:0002065 256 1.000
ovarian follicle cell development GO:0030707 248 0.999
columnar cuboidal epithelial cell development GO:0002066 249 0.999
tissue migration GO:0090130 155 0.998
actin filament based process GO:0030029 220 0.988
Human
ameboidal type cell migration GO:0001667 151 0.987
cell motility GO:0048870 251 0.987
actin filament organization GO:0007015 126 0.987
epithelial cell development GO:0002064 274 0.987
compound eye morphogenesis GO:0001745 249 0.983
eye photoreceptor cell differentiation GO:0001754 145 0.979
localization of cell GO:0051674 257 0.978
epithelium migration GO:0090132 148 0.972
tissue morphogenesis GO:0048729 297 0.941
rhabdomere development GO:0042052 38 0.908
cell migration GO:0016477 238 0.888
eye development GO:0001654 323 0.883
photoreceptor cell differentiation GO:0046530 170 0.881
establishment of ommatidial planar polarity GO:0042067 49 0.854
morphogenesis of an epithelium GO:0002009 276 0.850
actin filament bundle organization GO:0061572 28 0.848
embryo development ending in birth or egg hatching GO:0009792 152 0.835
tube morphogenesis GO:0035239 191 0.827
Fly
cellular component assembly involved in morphogenesis GO:0010927 151 0.826
actin cytoskeleton organization GO:0030036 206 0.823
Human
embryonic morphogenesis GO:0048598 206 0.813
Fly
establishment or maintenance of cell polarity GO:0007163 167 0.809
imaginal disc derived wing hair organization GO:0035317 45 0.789
compound eye development GO:0048749 307 0.750
regulation of protein tyrosine kinase activity GO:0061097 9 0.720
striated muscle cell differentiation GO:0051146 90 0.716
eggshell formation GO:0030703 105 0.716
Fly
actomyosin structure organization GO:0031032 56 0.716
compound eye photoreceptor cell differentiation GO:0001751 140 0.710
regulation of actin polymerization or depolymerization GO:0008064 27 0.709
sensory organ morphogenesis GO:0090596 260 0.706
regulation of actin filament polymerization GO:0030833 25 0.697
cell projection assembly GO:0030031 94 0.693
Human
developmental growth GO:0048589 280 0.673
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.660
dorsal closure GO:0007391 79 0.654
salivary gland development GO:0007431 162 0.650
non sensory hair organization GO:0035316 47 0.647
photoreceptor cell development GO:0042461 96 0.640
Fly
muscle cell differentiation GO:0042692 103 0.630
actin polymerization or depolymerization GO:0008154 31 0.618
muscle structure development GO:0061061 224 0.616
embryonic development via the syncytial blastoderm GO:0001700 148 0.603
initiation of dorsal closure GO:0007392 12 0.592
growth GO:0040007 359 0.584
Yeast Fly
tube development GO:0035295 244 0.578
Fly
negative regulation of cell communication GO:0010648 223 0.570
regulation of multicellular organismal development GO:2000026 414 0.564
Worm Fly
regulation of nervous system development GO:0051960 248 0.562
Fly
skin development GO:0043588 65 0.559
proteolysis GO:0006508 192 0.555
myoblast fusion GO:0007520 43 0.554
endocytosis GO:0006897 310 0.535
regulation of dendrite morphogenesis GO:0048814 28 0.530
regulation of actin filament length GO:0030832 27 0.530
gland development GO:0048732 191 0.527
compound eye photoreceptor fate commitment GO:0001752 36 0.525
actin filament bundle assembly GO:0051017 26 0.519
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.509
Yeast
regulation of cell morphogenesis GO:0022604 163 0.507
signal release GO:0023061 49 0.503
organelle localization GO:0051640 148 0.502
regulation of phosphate metabolic process GO:0019220 210 0.498
organelle assembly GO:0070925 198 0.491
positive regulation of response to stimulus GO:0048584 323 0.490
Fly
eye photoreceptor cell development GO:0042462 81 0.480
synaptic growth at neuromuscular junction GO:0051124 119 0.471
autophagy GO:0006914 108 0.470
Fly
hematopoietic or lymphoid organ development GO:0048534 57 0.465
Fly
regulation of actin cytoskeleton organization GO:0032956 42 0.450
hindgut morphogenesis GO:0007442 58 0.443
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.441
imaginal disc derived wing hair site selection GO:0035320 4 0.431
response to biotic stimulus GO:0009607 294 0.423
ommatidial rotation GO:0016318 20 0.414
respiratory system development GO:0060541 213 0.410
Fly
compound eye photoreceptor development GO:0042051 78 0.406
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.388
Fly
nuclear division GO:0000280 332 0.387
regulation of cell shape GO:0008360 113 0.387
catabolic process GO:0009056 409 0.370
dendrite morphogenesis GO:0048813 199 0.364
neuromuscular junction development GO:0007528 149 0.361
regulation of phosphorylation GO:0042325 147 0.356
cation transport GO:0006812 110 0.356
eye morphogenesis GO:0048592 260 0.354
endosomal transport GO:0016197 44 0.348
phosphorylation GO:0016310 294 0.344
open tracheal system development GO:0007424 204 0.343
Fly
response to osmotic stress GO:0006970 14 0.340
myotube differentiation GO:0014902 46 0.339
cellular catabolic process GO:0044248 372 0.339
appendage development GO:0048736 401 0.336
Fly
morphogenesis of a polarized epithelium GO:0001738 93 0.317
regulation of response to stress GO:0080134 200 0.317
actin filament polymerization GO:0030041 27 0.317
dendrite development GO:0016358 204 0.315
transcription from rna polymerase ii promoter GO:0006366 368 0.313
hemopoiesis GO:0030097 46 0.311
Fly
syncytium formation GO:0006949 43 0.311
morphogenesis of embryonic epithelium GO:0016331 94 0.310
larval development GO:0002164 104 0.298
Worm Fly
epithelial tube morphogenesis GO:0060562 88 0.294
epidermis development GO:0008544 65 0.294
negative regulation of signaling GO:0023057 219 0.288
regulation of actin filament based process GO:0032970 42 0.287
positive regulation of transcription dna templated GO:0045893 266 0.285
Yeast
germarium derived oocyte fate determination GO:0007294 26 0.283
gtp metabolic process GO:0046039 72 0.282
spermatogenesis GO:0007283 200 0.282
renal tubule development GO:0061326 64 0.280
Fly
rho protein signal transduction GO:0007266 14 0.272
filopodium assembly GO:0046847 33 0.270
Human
regulation of neurogenesis GO:0050767 158 0.269
Fly
regulation of cell differentiation GO:0045595 302 0.269
Fly
hemocyte migration GO:0035099 19 0.267
Fly
intracellular transport GO:0046907 228 0.262
Fly
negative regulation of developmental process GO:0051093 201 0.254
Fly
axonogenesis GO:0007409 290 0.253
r3 r4 cell differentiation GO:0048056 12 0.250
cellular response to extracellular stimulus GO:0031668 64 0.246
Yeast Fly
positive regulation of actin filament polymerization GO:0030838 11 0.243
regulation of proteolysis GO:0030162 87 0.237
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.236
cell junction assembly GO:0034329 42 0.236
syncytium formation by plasma membrane fusion GO:0000768 43 0.236
establishment of monopolar cell polarity GO:0061162 15 0.235
regulation of cell death GO:0010941 173 0.235
Fly
regulation of protein complex assembly GO:0043254 42 0.235
wing disc morphogenesis GO:0007472 344 0.234
Fly
establishment of spindle orientation GO:0051294 18 0.234
cell type specific apoptotic process GO:0097285 38 0.231
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.229
regulation of tube architecture open tracheal system GO:0035152 68 0.227
cuticle development GO:0042335 86 0.225
protein localization to plasma membrane GO:0072659 13 0.223
salivary gland morphogenesis GO:0007435 145 0.223
programmed cell death GO:0012501 257 0.223
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.222
nuclear migration GO:0007097 20 0.218
protein complex biogenesis GO:0070271 201 0.217
cell competition in a multicellular organism GO:0035212 10 0.217
regulation of establishment of planar polarity GO:0090175 22 0.215
branching involved in open tracheal system development GO:0060446 45 0.214
protein complex assembly GO:0006461 200 0.213
organonitrogen compound metabolic process GO:1901564 318 0.211
regulation of protein metabolic process GO:0051246 256 0.211
intracellular signal transduction GO:0035556 300 0.210
adherens junction organization GO:0034332 27 0.209
cortical actin cytoskeleton organization GO:0030866 24 0.209
dna metabolic process GO:0006259 227 0.209
guanosine containing compound metabolic process GO:1901068 74 0.205
exocrine system development GO:0035272 162 0.205
protein localization GO:0008104 284 0.204
Yeast Worm Fly
biological adhesion GO:0022610 138 0.204
macromolecular complex assembly GO:0065003 256 0.201
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.200
negative regulation of nucleic acid templated transcription GO:1903507 240 0.198
oocyte microtubule cytoskeleton organization GO:0016325 35 0.197
asymmetric protein localization GO:0008105 33 0.196
apoptotic process GO:0006915 159 0.195
Fly
regulation of stress activated mapk cascade GO:0032872 41 0.195
regulation of protein polymerization GO:0032271 28 0.195
cuticle pattern formation GO:0035017 27 0.193
spindle organization GO:0007051 253 0.192
single organism intracellular transport GO:1902582 207 0.191
Fly
guanosine containing compound catabolic process GO:1901069 74 0.190
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.190
digestive tract morphogenesis GO:0048546 127 0.189
Fly
establishment of spindle localization GO:0051293 22 0.189
small gtpase mediated signal transduction GO:0007264 88 0.189
regulation of organ morphogenesis GO:2000027 78 0.188
Fly
humoral immune response GO:0006959 117 0.188
regulation of programmed cell death GO:0043067 152 0.186
Fly
organelle fission GO:0048285 340 0.185
actin cytoskeleton reorganization GO:0031532 22 0.185
Human
establishment of body hair planar orientation GO:0048105 1 0.185
dorsal closure elongation of leading edge cells GO:0007394 10 0.183
positive regulation of protein tyrosine kinase activity GO:0061098 4 0.182
immune system process GO:0002376 347 0.180
dorsal closure spreading of leading edge cells GO:0007395 4 0.178
establishment of proximal distal cell polarity GO:0022606 4 0.178
dorsal closure amnioserosa morphology change GO:0046664 7 0.177
regulation of cytoskeleton organization GO:0051493 89 0.177
synapse assembly GO:0007416 143 0.175
regulation of organelle organization GO:0033043 196 0.173
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.170
glycosyl compound catabolic process GO:1901658 112 0.168
gland morphogenesis GO:0022612 145 0.167
negative regulation of rna biosynthetic process GO:1902679 240 0.165
cellular response to abiotic stimulus GO:0071214 58 0.163
meiotic cell cycle process GO:1903046 132 0.159
Yeast
regulation of developmental growth GO:0048638 174 0.159
Fly
epidermal cell differentiation GO:0009913 51 0.158
chorion containing eggshell formation GO:0007304 105 0.156
Fly
death GO:0016265 284 0.155
Fly
establishment of epithelial cell polarity GO:0090162 13 0.155
mitotic nuclear division GO:0007067 213 0.152
stress activated mapk cascade GO:0051403 52 0.151
regulation of response to external stimulus GO:0032101 115 0.151
Fly
ion transport GO:0006811 145 0.150
positive regulation of cell projection organization GO:0031346 29 0.149
Human
protein maturation GO:0051604 71 0.147
response to abiotic stimulus GO:0009628 341 0.145
pronuclear migration GO:0035046 4 0.144
single organism catabolic process GO:0044712 228 0.144
mapk cascade GO:0000165 107 0.142
gtp catabolic process GO:0006184 72 0.142
positive regulation of multi organism process GO:0043902 40 0.141
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.140
cell cell signaling involved in cell fate commitment GO:0045168 210 0.140
ras protein signal transduction GO:0007265 88 0.138
positive regulation of nucleic acid templated transcription GO:1903508 266 0.136
Yeast
response to organic cyclic compound GO:0014070 89 0.136
establishment of nucleus localization GO:0040023 26 0.135
organic substance catabolic process GO:1901575 308 0.132
negative regulation of biosynthetic process GO:0009890 277 0.132
regulation of cellular ketone metabolic process GO:0010565 3 0.131
immune response GO:0006955 246 0.130
regulation of localization GO:0032879 275 0.129
Human Yeast Mouse Worm
positive regulation of protein phosphorylation GO:0001934 34 0.128
carboxylic acid metabolic process GO:0019752 92 0.126
lamellipodium organization GO:0097581 21 0.125
hair cell differentiation GO:0035315 47 0.125
regulation of anatomical structure morphogenesis GO:0022603 242 0.124
positive regulation of phosphorus metabolic process GO:0010562 139 0.124
Yeast Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.123
Yeast
regulation of cellular component biogenesis GO:0044087 201 0.123
Human
striated muscle cell development GO:0055002 50 0.123
r7 cell differentiation GO:0045466 43 0.122
metal ion transport GO:0030001 74 0.121
regulation of neuron differentiation GO:0045664 103 0.121
Fly
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.120
establishment of localization in cell GO:0051649 402 0.120
Human Mouse Fly
regulation of lamellipodium organization GO:1902743 15 0.119
regulation of jnk cascade GO:0046328 40 0.119
regulation of cellular amine metabolic process GO:0033238 3 0.119
purine ribonucleoside metabolic process GO:0046128 127 0.119
cellular protein modification process GO:0006464 438 0.118
regulation of rho protein signal transduction GO:0035023 20 0.118
regulation of cell projection assembly GO:0060491 30 0.117
Human
cellular response to chemical stimulus GO:0070887 199 0.115
Yeast
protein polymerization GO:0051258 42 0.114
eggshell chorion assembly GO:0007306 66 0.112
regulation of intracellular signal transduction GO:1902531 236 0.112
response to bacterium GO:0009617 198 0.111
establishment of organelle localization GO:0051656 122 0.111
protein modification process GO:0036211 438 0.111
stem cell maintenance GO:0019827 67 0.109
purine ribonucleotide catabolic process GO:0009154 109 0.109
organic hydroxy compound metabolic process GO:1901615 83 0.109
lateral inhibition GO:0046331 206 0.108
regulation of synapse assembly GO:0051963 94 0.108
leg disc development GO:0035218 92 0.107
tor signaling GO:0031929 32 0.107
Fly
establishment of mitotic spindle localization GO:0040001 17 0.107
rna localization GO:0006403 115 0.106
cell death GO:0008219 279 0.106
Fly
positive regulation of rab gtpase activity GO:0032851 7 0.105
small molecule metabolic process GO:0044281 305 0.104
signal transduction by phosphorylation GO:0023014 107 0.102
positive regulation of axon extension GO:0045773 2 0.102
membrane protein ectodomain proteolysis GO:0006509 5 0.101
regulation of immune system process GO:0002682 176 0.101
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.101
endomembrane system organization GO:0010256 119 0.100
regulation of cell migration GO:0030334 22 0.100
regulation of cell projection organization GO:0031344 92 0.099
Human
morphogenesis of a branching structure GO:0001763 45 0.099
negative regulation of protein tyrosine kinase activity GO:0061099 5 0.099
oocyte fate determination GO:0030716 27 0.099
negative regulation of organ growth GO:0046621 15 0.098
regulation of dendrite development GO:0050773 37 0.098
jnk cascade GO:0007254 50 0.098
developmental maturation GO:0021700 172 0.098
Fly
negative regulation of gene expression GO:0010629 387 0.097
regulation of cellular protein metabolic process GO:0032268 243 0.096
microtubule based movement GO:0007018 51 0.096
regulation of cellular localization GO:0060341 136 0.094
Human Mouse Worm
regulation of r7 cell differentiation GO:0045676 15 0.093
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.093
skeletal muscle organ development GO:0060538 48 0.093
axon guidance GO:0007411 233 0.092
regulation of cellular component size GO:0032535 98 0.092
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.091
Fly
renal system process GO:0003014 12 0.091
regulation of molecular function GO:0065009 217 0.090
Yeast
regulation of lamellipodium assembly GO:0010591 15 0.090
positive regulation of cell development GO:0010720 61 0.090
Fly
striated muscle tissue development GO:0014706 27 0.090
regulation of endopeptidase activity GO:0052548 36 0.090
male gamete generation GO:0048232 201 0.090
neuron projection guidance GO:0097485 241 0.089
nucleoside phosphate metabolic process GO:0006753 162 0.089
negative regulation of cellular biosynthetic process GO:0031327 277 0.088
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.088
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.088
post embryonic appendage morphogenesis GO:0035120 385 0.087
Fly
positive regulation of cytoskeleton organization GO:0051495 21 0.087
nucleocytoplasmic transport GO:0006913 72 0.086
Fly
antimicrobial humoral response GO:0019730 99 0.086
spermatid development GO:0007286 98 0.086
regulation of photoreceptor cell differentiation GO:0046532 34 0.085
Fly
positive regulation of signaling GO:0023056 243 0.085
Fly
germarium derived egg chamber formation GO:0007293 101 0.084
regulation of locomotion GO:0040012 42 0.084
regulation of cell motility GO:2000145 23 0.084
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.083
cell growth GO:0016049 108 0.083
Yeast Fly
muscle cell development GO:0055001 50 0.082
regulation of synapse structure and activity GO:0050803 128 0.081
imaginal disc derived appendage morphogenesis GO:0035114 395 0.081
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.081
regulation of protein kinase activity GO:0045859 51 0.080
malpighian tubule development GO:0072002 64 0.080
Fly
peptidyl amino acid modification GO:0018193 105 0.080
morphogenesis of a branching epithelium GO:0061138 45 0.080
regulation of catalytic activity GO:0050790 185 0.080
Yeast
vesicle mediated transport GO:0016192 381 0.080
Human Mouse
negative regulation of programmed cell death GO:0043069 72 0.078
Fly
nucleus localization GO:0051647 34 0.078
positive regulation of intracellular signal transduction GO:1902533 116 0.078
Fly
purine nucleotide catabolic process GO:0006195 109 0.077
regulation of axonogenesis GO:0050770 32 0.077
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.077
regulation of neuron projection development GO:0010975 69 0.077
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.076
maintenance of apical basal cell polarity GO:0035090 8 0.076
positive regulation of filopodium assembly GO:0051491 15 0.076
Human
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.075
myofibril assembly GO:0030239 36 0.075
photoreceptor cell fate commitment GO:0046552 41 0.073
notch receptor processing GO:0007220 13 0.071
meiotic spindle organization GO:0000212 36 0.071
asymmetric stem cell division GO:0098722 49 0.071
positive regulation of nervous system development GO:0051962 69 0.071
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.070
regulation of apoptotic process GO:0042981 130 0.069
Fly
germarium derived oocyte differentiation GO:0030706 29 0.069
ion transmembrane transport GO:0034220 122 0.068
negative regulation of growth GO:0045926 84 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.068
Yeast
enzyme linked receptor protein signaling pathway GO:0007167 179 0.068
Worm
chaeta morphogenesis GO:0008407 42 0.068
positive regulation of cell communication GO:0010647 250 0.068
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.067
Yeast
epithelial cell proliferation GO:0050673 15 0.067
spindle assembly GO:0051225 80 0.067
negative regulation of imaginal disc growth GO:0045571 8 0.066
erbb signaling pathway GO:0038127 58 0.066
Worm
positive regulation of macromolecule metabolic process GO:0010604 405 0.066
Yeast
negative regulation of transcription dna templated GO:0045892 237 0.066
cellular macromolecular complex assembly GO:0034622 153 0.066
eye photoreceptor cell fate commitment GO:0042706 37 0.066
branching morphogenesis of an epithelial tube GO:0048754 45 0.066
salivary gland histolysis GO:0035070 88 0.065
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.065
intracellular protein transport GO:0006886 104 0.065
Fly
purine ribonucleoside catabolic process GO:0046130 112 0.064
response to inorganic substance GO:0010035 44 0.063
establishment of neuroblast polarity GO:0045200 2 0.063
microtubule based transport GO:0010970 42 0.063
positive regulation of cell migration GO:0030335 2 0.063
negative regulation of apoptotic process GO:0043066 63 0.063
Fly
immune system development GO:0002520 57 0.062
Fly
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.061
ribonucleoside catabolic process GO:0042454 112 0.060
chromosome organization GO:0051276 360 0.060
apoptotic cell clearance GO:0043277 14 0.059
cortical cytoskeleton organization GO:0030865 29 0.058
histolysis GO:0007559 102 0.058
regulation of nucleotide catabolic process GO:0030811 48 0.058
regulation of endocytosis GO:0030100 37 0.058
cellular protein catabolic process GO:0044257 83 0.057
cellular ketone metabolic process GO:0042180 24 0.057
cell division GO:0051301 248 0.057
Human
axon extension GO:0048675 32 0.057
establishment of cell polarity GO:0030010 40 0.056
transmembrane transport GO:0055085 139 0.056
regulation of epithelial cell proliferation GO:0050678 4 0.056
positive regulation of gene expression GO:0010628 290 0.056
Yeast
lipid metabolic process GO:0006629 121 0.056
positive regulation of phosphate metabolic process GO:0045937 139 0.056
Yeast Fly
regulation of purine nucleotide metabolic process GO:1900542 62 0.055
Yeast
regulation of synapse organization GO:0050807 110 0.055
dorsal appendage formation GO:0046843 47 0.055
cardiac cell fate specification GO:0060912 10 0.055
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.055
head involution GO:0008258 35 0.055
response to oxygen containing compound GO:1901700 200 0.054
synapse organization GO:0050808 196 0.054
protein phosphorylation GO:0006468 169 0.054
striated muscle myosin thick filament assembly GO:0071688 3 0.054
autophagic cell death GO:0048102 83 0.054
peptidyl tyrosine phosphorylation GO:0018108 24 0.054
regulation of filopodium assembly GO:0051489 24 0.053
Human
receptor mediated endocytosis GO:0006898 21 0.053
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.053
wnt signaling pathway GO:0016055 98 0.053
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.052
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.052
Fly
cellularization GO:0007349 90 0.052
induction of programmed cell death GO:0012502 12 0.052
developmental programmed cell death GO:0010623 138 0.052
Fly
germ line cyst formation GO:0048134 44 0.052
nucleoside triphosphate metabolic process GO:0009141 120 0.051
regulation of purine nucleotide catabolic process GO:0033121 48 0.051
imaginal disc derived leg morphogenesis GO:0007480 80 0.051
positive regulation of neuron differentiation GO:0045666 26 0.051
Fly
negative regulation of developmental growth GO:0048640 64 0.051
microtubule organizing center organization GO:0031023 168 0.051
stress activated protein kinase signaling cascade GO:0031098 55 0.051
regulation of cell cycle process GO:0010564 181 0.051
macroautophagy GO:0016236 42 0.051
Fly
positive regulation of protein kinase activity GO:0045860 25 0.051
neuroblast proliferation GO:0007405 74 0.050
peptidyl tyrosine modification GO:0018212 24 0.050
cellular lipid metabolic process GO:0044255 83 0.050
spindle localization GO:0051653 22 0.050
spermatid differentiation GO:0048515 114 0.050
aging GO:0007568 143 0.049
Yeast Worm
telencephalon development GO:0021537 2 0.049
regulation of ras gtpase activity GO:0032318 38 0.049
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.049
establishment of mitotic spindle orientation GO:0000132 13 0.049
response to metal ion GO:0010038 23 0.049
positive regulation of protein metabolic process GO:0051247 128 0.048
appendage morphogenesis GO:0035107 397 0.048
Fly
cellular response to external stimulus GO:0071496 66 0.048
Yeast Fly
amine metabolic process GO:0009308 12 0.048
positive regulation of cellular protein metabolic process GO:0032270 118 0.048
neural retina development GO:0003407 4 0.048
nucleobase containing small molecule metabolic process GO:0055086 174 0.048
camera type eye photoreceptor cell differentiation GO:0060219 2 0.048
hematopoietic progenitor cell differentiation GO:0002244 1 0.047
regulation of nucleotide metabolic process GO:0006140 62 0.047
Yeast
head development GO:0060322 135 0.047
digestive system development GO:0055123 149 0.047
Fly
cellular macromolecule localization GO:0070727 220 0.047
Yeast Worm Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.047
defense response GO:0006952 300 0.047
reproductive structure development GO:0048608 74 0.046
collateral sprouting GO:0048668 3 0.046
neuroblast division GO:0055057 35 0.046
positive regulation of jun kinase activity GO:0043507 4 0.045
apical protein localization GO:0045176 5 0.045
leg disc morphogenesis GO:0007478 80 0.045
regulation of cell division GO:0051302 72 0.045
regulation of cellular component movement GO:0051270 42 0.045
positive regulation of tor signaling GO:0032008 13 0.044
rac protein signal transduction GO:0016601 3 0.044
positive regulation of rna metabolic process GO:0051254 271 0.044
Yeast
somatic stem cell division GO:0048103 37 0.043
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.043
positive regulation of cell growth GO:0030307 19 0.043
positive regulation of cellular component organization GO:0051130 156 0.043
Human
heart development GO:0007507 82 0.043
axon extension involved in axon guidance GO:0048846 10 0.043
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.042
taxis GO:0042330 304 0.042
defense response to other organism GO:0098542 225 0.042
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.042
positive regulation of phosphorylation GO:0042327 87 0.042
Fly
regulation of mitotic cell cycle GO:0007346 190 0.042
positive regulation of developmental growth GO:0048639 62 0.042
synaptic transmission GO:0007268 288 0.042
positive regulation of signal transduction GO:0009967 223 0.042
Fly
myosin filament organization GO:0031033 5 0.042
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.042
positive regulation of protein localization to plasma membrane GO:1903078 3 0.042
asymmetric cell division GO:0008356 37 0.042
regulation of nucleoside metabolic process GO:0009118 50 0.042
negative regulation of rna metabolic process GO:0051253 251 0.041
positive regulation of cell motility GO:2000147 3 0.041
positive regulation of transport GO:0051050 92 0.041
golgi to plasma membrane protein transport GO:0043001 8 0.041
regulation of embryonic cell shape GO:0016476 30 0.041
regulation of defense response GO:0031347 102 0.040
purine nucleoside metabolic process GO:0042278 127 0.040
determination of adult lifespan GO:0008340 137 0.040
Worm

Rala disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
non syndromic intellectual disability DOID:0050889 0 0.049
disease of mental health DOID:150 0 0.049
developmental disorder of mental health DOID:0060037 0 0.049
specific developmental disorder DOID:0060038 0 0.049
intellectual disability DOID:1059 0 0.049
motor neuron disease DOID:231 0 0.048
central nervous system disease DOID:331 0 0.048
disease of anatomical entity DOID:7 0 0.048
neurodegenerative disease DOID:1289 0 0.048
nervous system disease DOID:863 0 0.048