Drosophila melanogaster

40 known processes

Pi4KIIalpha (Dmel_CG2929)

CG2929 gene product from transcript CG2929-RC

(Aliases: PI4KIIbeta,Dmel\CG2929,CG2929,PI4KII,PI4KIIalpha)

Pi4KIIalpha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.335
intracellular transport GO:0046907 228 0.217
regulation of localization GO:0032879 275 0.210
response to light stimulus GO:0009416 124 0.170
response to radiation GO:0009314 155 0.166
pigment biosynthetic process GO:0046148 36 0.155
pigment metabolic process GO:0042440 84 0.149
regulation of transport GO:0051049 181 0.143
lipid metabolic process GO:0006629 121 0.143
single organism membrane fusion GO:0044801 42 0.141
regulation of multicellular organismal development GO:2000026 414 0.113
protein transport GO:0015031 155 0.109
sphingolipid metabolic process GO:0006665 19 0.106
single organism intracellular transport GO:1902582 207 0.100
organonitrogen compound metabolic process GO:1901564 318 0.099
establishment of organelle localization GO:0051656 122 0.093
single organism biosynthetic process GO:0044711 206 0.093
cellular macromolecule localization GO:0070727 220 0.092
regulation of nervous system development GO:0051960 248 0.090
protein localization GO:0008104 284 0.089
gland morphogenesis GO:0022612 145 0.088
gland development GO:0048732 191 0.084
membrane organization GO:0061024 112 0.083
spermatid differentiation GO:0048515 114 0.083
negative regulation of cellular metabolic process GO:0031324 382 0.082
imaginal disc derived appendage morphogenesis GO:0035114 395 0.080
positive regulation of cellular component organization GO:0051130 156 0.080
regulation of cellular component size GO:0032535 98 0.079
organic substance catabolic process GO:1901575 308 0.079
cell motility GO:0048870 251 0.071
organic substance transport GO:0071702 257 0.071
small molecule metabolic process GO:0044281 305 0.070
single organism membrane organization GO:0044802 93 0.068
regulation of neuron differentiation GO:0045664 103 0.067
regulation of cellular localization GO:0060341 136 0.067
regulation of developmental growth GO:0048638 174 0.066
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.066
catabolic process GO:0009056 409 0.064
cellular catabolic process GO:0044248 372 0.063
regulation of synapse assembly GO:0051963 94 0.063
death GO:0016265 284 0.063
positive regulation of transport GO:0051050 92 0.062
chromatin organization GO:0006325 207 0.062
pigment metabolic process involved in pigmentation GO:0043474 33 0.058
epithelial cell differentiation GO:0030855 322 0.057
carboxylic acid metabolic process GO:0019752 92 0.057
tissue death GO:0016271 102 0.056
establishment of protein localization GO:0045184 163 0.055
positive regulation of response to stimulus GO:0048584 323 0.055
regulation of cellular component biogenesis GO:0044087 201 0.054
eye pigment biosynthetic process GO:0006726 32 0.053
eye morphogenesis GO:0048592 260 0.053
post embryonic appendage morphogenesis GO:0035120 385 0.053
histolysis GO:0007559 102 0.052
protein modification process GO:0036211 438 0.051
positive regulation of macromolecule metabolic process GO:0010604 405 0.051
intracellular protein transport GO:0006886 104 0.050
developmental programmed cell death GO:0010623 138 0.049
eye pigment metabolic process GO:0042441 33 0.048
cellular response to nutrient levels GO:0031669 62 0.045
oxoacid metabolic process GO:0043436 103 0.045
germ cell migration GO:0008354 43 0.044
regulation of protein metabolic process GO:0051246 256 0.043
membrane lipid metabolic process GO:0006643 22 0.042
negative regulation of cellular protein metabolic process GO:0032269 85 0.042
cellular protein complex disassembly GO:0043624 35 0.041
salivary gland development GO:0007431 162 0.041
negative regulation of cellular component organization GO:0051129 108 0.041
endocytosis GO:0006897 310 0.040
regulation of protein complex disassembly GO:0043244 29 0.040
single organism cellular localization GO:1902580 180 0.040
regulation of growth GO:0040008 233 0.040
vesicle localization GO:0051648 55 0.040
regulation of cell size GO:0008361 63 0.040
central nervous system development GO:0007417 201 0.040
salivary gland morphogenesis GO:0007435 145 0.040
chromosome organization GO:0051276 360 0.039
response to other organism GO:0051707 293 0.039
asymmetric cell division GO:0008356 37 0.039
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.039
intracellular signal transduction GO:0035556 300 0.039
organelle localization GO:0051640 148 0.039
positive regulation of signal transduction GO:0009967 223 0.039
endomembrane system organization GO:0010256 119 0.038
regulation of establishment of protein localization GO:0070201 61 0.038
lysosomal transport GO:0007041 13 0.038
cellular nitrogen compound catabolic process GO:0044270 165 0.038
male gamete generation GO:0048232 201 0.038
regulation of synapse structure and activity GO:0050803 128 0.037
regulation of synapse organization GO:0050807 110 0.037
vesicle mediated transport GO:0016192 381 0.037
axonogenesis GO:0007409 290 0.037
regulation of organelle organization GO:0033043 196 0.037
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.037
cell death GO:0008219 279 0.036
muscle structure development GO:0061061 224 0.036
positive regulation of signaling GO:0023056 243 0.036
cellularization GO:0007349 90 0.036
salivary gland cell autophagic cell death GO:0035071 83 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.036
cellular protein modification process GO:0006464 438 0.036
appendage development GO:0048736 401 0.036
synapse organization GO:0050808 196 0.036
developmental growth GO:0048589 280 0.035
spermatogenesis GO:0007283 200 0.035
positive regulation of multicellular organismal process GO:0051240 143 0.035
autophagic cell death GO:0048102 83 0.035
regulation of vesicle mediated transport GO:0060627 59 0.034
organic acid metabolic process GO:0006082 103 0.034
ovarian follicle cell development GO:0030707 248 0.033
response to abiotic stimulus GO:0009628 341 0.033
salivary gland histolysis GO:0035070 88 0.033
telencephalon development GO:0021537 2 0.032
macromolecular complex assembly GO:0065003 256 0.032
detection of stimulus GO:0051606 156 0.032
phosphorylation GO:0016310 294 0.032
programmed cell death GO:0012501 257 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.031
regulation of intracellular transport GO:0032386 64 0.031
regulation of catabolic process GO:0009894 170 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
synapse assembly GO:0007416 143 0.031
cellular protein localization GO:0034613 160 0.031
regulation of cellular ketone metabolic process GO:0010565 3 0.030
actin cytoskeleton organization GO:0030036 206 0.030
forebrain development GO:0030900 2 0.030
positive regulation of programmed cell death GO:0043068 62 0.030
regulation of cell development GO:0060284 215 0.029
positive regulation of cell communication GO:0010647 250 0.029
photoreceptor cell development GO:0042461 96 0.029
detection of external stimulus GO:0009581 66 0.029
organelle assembly GO:0070925 198 0.028
sensory organ morphogenesis GO:0090596 260 0.028
body morphogenesis GO:0010171 2 0.028
detection of light stimulus GO:0009583 58 0.028
regulation of cell death GO:0010941 173 0.028
response to extracellular stimulus GO:0009991 116 0.028
cell migration GO:0016477 238 0.028
epidermal cell differentiation GO:0009913 51 0.027
meiotic cell cycle process GO:1903046 132 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
regulation of protein transport GO:0051223 57 0.027
macromolecule catabolic process GO:0009057 161 0.027
wing disc morphogenesis GO:0007472 344 0.027
purine nucleoside metabolic process GO:0042278 127 0.027
cellular macromolecule catabolic process GO:0044265 136 0.026
heterocycle catabolic process GO:0046700 166 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.025
response to nutrient levels GO:0031667 114 0.025
neurological system process GO:0050877 358 0.025
anatomical structure homeostasis GO:0060249 97 0.025
regulation of response to extracellular stimulus GO:0032104 18 0.025
positive regulation of cellular biosynthetic process GO:0031328 316 0.025
regulation of cell differentiation GO:0045595 302 0.025
dorsal ventral pattern formation GO:0009953 133 0.025
single organism behavior GO:0044708 391 0.025
rna processing GO:0006396 147 0.025
detection of abiotic stimulus GO:0009582 66 0.025
organic hydroxy compound metabolic process GO:1901615 83 0.024
endosomal transport GO:0016197 44 0.024
proteolysis GO:0006508 192 0.024
regulation of cell cycle GO:0051726 291 0.024
single organism catabolic process GO:0044712 228 0.024
cell maturation GO:0048469 144 0.024
regionalization GO:0003002 416 0.024
cellular ketone metabolic process GO:0042180 24 0.024
eye pigmentation GO:0048069 43 0.023
cellular response to starvation GO:0009267 61 0.023
organelle fusion GO:0048284 46 0.023
response to external biotic stimulus GO:0043207 293 0.023
secretion GO:0046903 109 0.023
cytoplasmic transport GO:0016482 130 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
cellular amine metabolic process GO:0044106 12 0.023
protein modification by small protein removal GO:0070646 28 0.022
regulation of protein localization GO:0032880 76 0.022
regulation of cellular catabolic process GO:0031329 157 0.022
phagocytosis GO:0006909 215 0.022
positive regulation of gene expression GO:0010628 290 0.022
axon development GO:0061564 297 0.022
positive regulation of cell death GO:0010942 69 0.022
negative regulation of gene expression GO:0010629 387 0.022
cell proliferation GO:0008283 299 0.022
nucleotide metabolic process GO:0009117 161 0.022
regulation of notch signaling pathway GO:0008593 100 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
positive regulation of apoptotic process GO:0043065 47 0.021
response to biotic stimulus GO:0009607 294 0.021
protein targeting GO:0006605 64 0.021
spermatid development GO:0007286 98 0.021
purine containing compound metabolic process GO:0072521 155 0.021
nucleoside metabolic process GO:0009116 127 0.021
actin filament based process GO:0030029 220 0.021
response to starvation GO:0042594 97 0.021
regulation of cell morphogenesis GO:0022604 163 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
organelle fission GO:0048285 340 0.021
sperm individualization GO:0007291 48 0.021
ceramide metabolic process GO:0006672 7 0.021
ras protein signal transduction GO:0007265 88 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
golgi organization GO:0007030 66 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.020
negative regulation of protein metabolic process GO:0051248 85 0.020
respiratory system development GO:0060541 213 0.020
regulation of anatomical structure size GO:0090066 163 0.020
regulation of response to external stimulus GO:0032101 115 0.020
nuclear division GO:0000280 332 0.020
defense response to other organism GO:0098542 225 0.019
segmentation GO:0035282 207 0.019
regulation of wnt signaling pathway GO:0030111 68 0.019
cardiocyte differentiation GO:0035051 29 0.019
positive regulation of developmental growth GO:0048639 62 0.019
synaptic transmission GO:0007268 288 0.019
regulation of cytoplasmic transport GO:1903649 47 0.019
posttranscriptional gene silencing GO:0016441 46 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
cellular lipid metabolic process GO:0044255 83 0.019
regulation of neuron projection development GO:0010975 69 0.019
meiotic nuclear division GO:0007126 151 0.019
regulation of catalytic activity GO:0050790 185 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
intercellular bridge organization GO:0043063 14 0.018
regulation of endocytosis GO:0030100 37 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
epithelial cell development GO:0002064 274 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
chromatin modification GO:0016568 147 0.018
negative regulation of organelle organization GO:0010639 56 0.018
protein complex assembly GO:0006461 200 0.018
regulation of phosphorylation GO:0042325 147 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
peripheral nervous system development GO:0007422 52 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
aging GO:0007568 143 0.018
stem cell proliferation GO:0072089 88 0.017
phototransduction GO:0007602 52 0.017
nucleotide catabolic process GO:0009166 109 0.017
macroautophagy GO:0016236 42 0.017
epidermal growth factor receptor signaling pathway GO:0007173 58 0.017
autophagy GO:0006914 108 0.017
digestive system development GO:0055123 149 0.017
regulation of neurogenesis GO:0050767 158 0.017
germarium derived egg chamber formation GO:0007293 101 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
synaptic growth at neuromuscular junction GO:0051124 119 0.017
ion transport GO:0006811 145 0.017
negative regulation of growth GO:0045926 84 0.017
non sensory hair organization GO:0035316 47 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
lipid localization GO:0010876 54 0.017
adult behavior GO:0030534 137 0.016
peptidyl amino acid modification GO:0018193 105 0.016
epithelial cell migration GO:0010631 148 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
negative regulation of developmental growth GO:0048640 64 0.016
regulation of response to stress GO:0080134 200 0.016
response to oxygen containing compound GO:1901700 200 0.016
regulation of cellular response to stress GO:0080135 89 0.016
neurotransmitter transport GO:0006836 37 0.016
organelle membrane fusion GO:0090174 16 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
exocrine system development GO:0035272 162 0.016
regulation of apoptotic process GO:0042981 130 0.016
establishment of synaptic vesicle localization GO:0097480 50 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
positive regulation of lipid metabolic process GO:0045834 4 0.016
cation transport GO:0006812 110 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
regulation of molecular function GO:0065009 217 0.016
regulation of hydrolase activity GO:0051336 97 0.016
macromolecular complex disassembly GO:0032984 37 0.016
positive regulation of catabolic process GO:0009896 105 0.015
rna localization GO:0006403 115 0.015
eye photoreceptor cell differentiation GO:0001754 145 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
secretion by cell GO:0032940 101 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
aromatic compound catabolic process GO:0019439 166 0.015
negative regulation of nervous system development GO:0051961 92 0.015
dendrite development GO:0016358 204 0.015
positive regulation of apoptotic signaling pathway GO:2001235 4 0.015
eye photoreceptor cell development GO:0042462 81 0.015
eye pigment granule organization GO:0008057 12 0.015
chemotaxis GO:0006935 249 0.015
growth GO:0040007 359 0.015
covalent chromatin modification GO:0016569 106 0.015
apoptotic process GO:0006915 159 0.015
histone modification GO:0016570 106 0.015
multicellular organismal aging GO:0010259 140 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
immune system process GO:0002376 347 0.014
wnt signaling pathway GO:0016055 98 0.014
erbb signaling pathway GO:0038127 58 0.014
cellular response to abiotic stimulus GO:0071214 58 0.014
neurotransmitter secretion GO:0007269 35 0.014
imaginal disc derived leg morphogenesis GO:0007480 80 0.014
appendage morphogenesis GO:0035107 397 0.014
positive regulation of nervous system development GO:0051962 69 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
lipid biosynthetic process GO:0008610 46 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
autophagic vacuole fusion GO:0000046 15 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
protein complex disassembly GO:0043241 36 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
cellular modified amino acid metabolic process GO:0006575 45 0.014
protein acylation GO:0043543 42 0.014
taxis GO:0042330 304 0.014
defense response GO:0006952 300 0.013
open tracheal system development GO:0007424 204 0.013
positive regulation of intracellular protein transport GO:0090316 30 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
axon guidance GO:0007411 233 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
negative regulation of signal transduction GO:0009968 206 0.013
cytoskeleton dependent intracellular transport GO:0030705 44 0.013
regulation of proteolysis GO:0030162 87 0.013
hindbrain development GO:0030902 2 0.013
regulation of photoreceptor cell differentiation GO:0046532 34 0.013
immune effector process GO:0002252 98 0.013
regulation of programmed cell death GO:0043067 152 0.013
metal ion transport GO:0030001 74 0.013
response to glucose GO:0009749 2 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
protein phosphorylation GO:0006468 169 0.013
acid secretion GO:0046717 1 0.013
muscle cell differentiation GO:0042692 103 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
regulation of mapk cascade GO:0043408 92 0.013
homeostatic process GO:0042592 199 0.013
membrane fusion GO:0061025 42 0.013
establishment of planar polarity GO:0001736 87 0.013
regulation of organ morphogenesis GO:2000027 78 0.013
gliogenesis GO:0042063 80 0.013
male meiosis GO:0007140 52 0.013
secondary metabolic process GO:0019748 75 0.013
developmental pigmentation GO:0048066 68 0.012
brain development GO:0007420 120 0.012
protein targeting to nucleus GO:0044744 51 0.012
regulation of secretion GO:0051046 44 0.012
female meiosis chromosome segregation GO:0016321 33 0.012
muscle organ development GO:0007517 127 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
nitrogen compound transport GO:0071705 85 0.012
localization of cell GO:0051674 257 0.012
meiotic cell cycle GO:0051321 171 0.012
establishment of vesicle localization GO:0051650 51 0.012
response to hexose GO:0009746 3 0.012
cellular response to extracellular stimulus GO:0031668 64 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
positive regulation of developmental process GO:0051094 143 0.012
ommochrome biosynthetic process GO:0006727 19 0.012
endosome to lysosome transport GO:0008333 7 0.012
skin development GO:0043588 65 0.012
regulation of protein targeting GO:1903533 29 0.012
monovalent inorganic cation transport GO:0015672 40 0.012
response to organic substance GO:0010033 284 0.012
mitochondrion organization GO:0007005 65 0.012
cellular response to light stimulus GO:0071482 37 0.011
signal release GO:0023061 49 0.011
compound eye morphogenesis GO:0001745 249 0.011
negative regulation of erbb signaling pathway GO:1901185 29 0.011
positive regulation of synapse assembly GO:0051965 29 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
regulation of multi organism process GO:0043900 131 0.011
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.011
regulation of translation GO:0006417 56 0.011
response to organophosphorus GO:0046683 2 0.011
regulation of cell cycle process GO:0010564 181 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
digestive tract morphogenesis GO:0048546 127 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
amine metabolic process GO:0009308 12 0.011
mrna processing GO:0006397 104 0.011
negative regulation of molecular function GO:0044092 51 0.011
nucleoside catabolic process GO:0009164 112 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
regulation of cell division GO:0051302 72 0.011
pigmentation GO:0043473 75 0.011
germline ring canal formation GO:0030725 13 0.011
positive regulation of molecular function GO:0044093 136 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
regulation of gtpase activity GO:0043087 44 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
atp metabolic process GO:0046034 49 0.011
camera type eye morphogenesis GO:0048593 2 0.011
cell division GO:0051301 248 0.011
response to alcohol GO:0097305 95 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
epithelium migration GO:0090132 148 0.011
protein import GO:0017038 55 0.011
positive regulation of cell motility GO:2000147 3 0.010
regulation of neurotransmitter levels GO:0001505 38 0.010
positive regulation of neurogenesis GO:0050769 41 0.010
hair cell differentiation GO:0035315 47 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
organophosphate catabolic process GO:0046434 112 0.010
developmental maturation GO:0021700 172 0.010
carbohydrate metabolic process GO:0005975 82 0.010
rna transport GO:0050658 46 0.010
epidermis development GO:0008544 65 0.010
cell fate determination GO:0001709 91 0.010
positive regulation of ras gtpase activity GO:0032320 36 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.010
regulation of synaptic transmission GO:0050804 69 0.010
leg disc morphogenesis GO:0007478 80 0.010
potassium ion transport GO:0006813 20 0.010
golgi vesicle transport GO:0048193 27 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
histone h4 k16 acetylation GO:0043984 4 0.010

Pi4KIIalpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
sensory system disease DOID:0050155 0 0.022
nervous system disease DOID:863 0 0.022
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
urinary system disease DOID:18 0 0.012
disease of metabolism DOID:0014667 0 0.010