Drosophila melanogaster

149 known processes

G9a (Dmel_CG2995)

CG2995 gene product from transcript CG2995-RA

(Aliases: cab65850 G9a Dm,EG:BACR37P7.2,CG2995,Dmel\CG2995,dG9a)

G9a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of gene expression epigenetic GO:0040029 128 0.835
Mouse
chromatin silencing GO:0006342 76 0.812
gene silencing GO:0016458 138 0.773
negative regulation of cellular metabolic process GO:0031324 382 0.690
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.689
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.686
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.646
Mouse
negative regulation of gene expression GO:0010629 387 0.644
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.624
Mouse
regulation of cell differentiation GO:0045595 302 0.614
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.589
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.488
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.475
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.470
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.420
positive regulation of rna metabolic process GO:0051254 271 0.386
transcription from rna polymerase ii promoter GO:0006366 368 0.355
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.331
regulation of growth GO:0040008 233 0.319
positive regulation of macromolecule metabolic process GO:0010604 405 0.311
organic acid metabolic process GO:0006082 103 0.304
negative regulation of transcription dna templated GO:0045892 237 0.282
Mouse
regulation of catabolic process GO:0009894 170 0.266
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.264
Mouse
growth GO:0040007 359 0.261
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.257
chromatin organization GO:0006325 207 0.248
negative regulation of cellular biosynthetic process GO:0031327 277 0.243
Mouse
brain development GO:0007420 120 0.221
negative regulation of biosynthetic process GO:0009890 277 0.214
Mouse
negative regulation of gene expression epigenetic GO:0045814 77 0.214
protein modification process GO:0036211 438 0.209
negative regulation of developmental process GO:0051093 201 0.203
embryonic development via the syncytial blastoderm GO:0001700 148 0.201
positive regulation of protein metabolic process GO:0051247 128 0.190
developmental growth GO:0048589 280 0.189
cellular response to organic substance GO:0071310 132 0.185
methylation GO:0032259 47 0.177
embryo development ending in birth or egg hatching GO:0009792 152 0.176
oxoacid metabolic process GO:0043436 103 0.175
negative regulation of immune system process GO:0002683 50 0.165
positive regulation of biosynthetic process GO:0009891 316 0.163
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.161
cellular protein modification process GO:0006464 438 0.160
neuromuscular junction development GO:0007528 149 0.151
negative regulation of cellular component organization GO:0051129 108 0.149
eye morphogenesis GO:0048592 260 0.140
synaptic growth at neuromuscular junction GO:0051124 119 0.137
amine metabolic process GO:0009308 12 0.134
positive regulation of nucleic acid templated transcription GO:1903508 266 0.134
dorsal closure GO:0007391 79 0.132
regulation of cellular amino acid metabolic process GO:0006521 0 0.131
regulation of developmental growth GO:0048638 174 0.128
positive regulation of cellular component organization GO:0051130 156 0.120
regulation of multicellular organismal development GO:2000026 414 0.117
negative regulation of cell differentiation GO:0045596 143 0.112
cellular amino acid metabolic process GO:0006520 61 0.111
regulation of cellular protein metabolic process GO:0032268 243 0.109
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.107
learning or memory GO:0007611 141 0.105
cell proliferation GO:0008283 299 0.104
detection of visible light GO:0009584 38 0.099
morphogenesis of an epithelium GO:0002009 276 0.098
regulation of cellular amine metabolic process GO:0033238 3 0.095
homeostatic process GO:0042592 199 0.091
regulation of chromosome organization GO:0033044 64 0.090
positive regulation of ras gtpase activity GO:0032320 36 0.087
protein localization GO:0008104 284 0.087
cellular protein localization GO:0034613 160 0.087
eye development GO:0001654 323 0.087
developmental maturation GO:0021700 172 0.082
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.080
Mouse
neuron projection guidance GO:0097485 241 0.080
chromosome organization GO:0051276 360 0.078
positive regulation of gene expression GO:0010628 290 0.078
regulation of protein modification process GO:0031399 112 0.076
compound eye development GO:0048749 307 0.076
cellular response to dna damage stimulus GO:0006974 223 0.072
positive regulation of cellular protein metabolic process GO:0032270 118 0.072
ubiquitin dependent protein catabolic process GO:0006511 78 0.070
peptidyl tyrosine phosphorylation GO:0018108 24 0.069
negative regulation of multicellular organismal process GO:0051241 142 0.068
cellular amine metabolic process GO:0044106 12 0.067
regulation of phosphorus metabolic process GO:0051174 210 0.067
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.067
single organism behavior GO:0044708 391 0.066
carboxylic acid metabolic process GO:0019752 92 0.065
response to organic cyclic compound GO:0014070 89 0.065
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.065
reproductive behavior GO:0019098 122 0.064
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.062
response to organic substance GO:0010033 284 0.061
intracellular signal transduction GO:0035556 300 0.061
regulation of cellular component biogenesis GO:0044087 201 0.060
regulation of cellular catabolic process GO:0031329 157 0.059
chromosome separation GO:0051304 42 0.059
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.058
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.058
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.058
regulation of response to stress GO:0080134 200 0.057
histone methylation GO:0016571 40 0.056
cell cycle phase transition GO:0044770 140 0.055
neurological system process GO:0050877 358 0.054
chromatin remodeling GO:0006338 72 0.054
cellular response to chemical stimulus GO:0070887 199 0.054
dna metabolic process GO:0006259 227 0.054
Human Mouse
protein alkylation GO:0008213 43 0.053
establishment of localization in cell GO:0051649 402 0.053
post embryonic hemopoiesis GO:0035166 17 0.052
negative regulation of organelle organization GO:0010639 56 0.052
response to lipid GO:0033993 38 0.052
cellular ketone metabolic process GO:0042180 24 0.051
regulation of epithelial cell differentiation GO:0030856 4 0.050
positive regulation of molecular function GO:0044093 136 0.050
establishment or maintenance of cell polarity GO:0007163 167 0.049
catabolic process GO:0009056 409 0.049
regulation of defense response GO:0031347 102 0.048
regulation of cell development GO:0060284 215 0.048
telencephalon development GO:0021537 2 0.047
compound eye morphogenesis GO:0001745 249 0.047
histone lysine methylation GO:0034968 32 0.046
protein catabolic process GO:0030163 101 0.046
chaeta development GO:0022416 97 0.045
immune system process GO:0002376 347 0.045
morphogenesis of embryonic epithelium GO:0016331 94 0.045
regulation of cellular ketone metabolic process GO:0010565 3 0.044
response to oxygen containing compound GO:1901700 200 0.044
positive regulation of catalytic activity GO:0043085 118 0.043
myotube cell development GO:0014904 3 0.043
negative regulation of response to stimulus GO:0048585 258 0.043
response to abiotic stimulus GO:0009628 341 0.042
gland development GO:0048732 191 0.042
positive regulation of protein modification process GO:0031401 58 0.042
regulation of protein metabolic process GO:0051246 256 0.041
positive regulation of protein phosphorylation GO:0001934 34 0.041
protein transport GO:0015031 155 0.041
organic substance catabolic process GO:1901575 308 0.040
cellular catabolic process GO:0044248 372 0.040
regulation of cellular protein catabolic process GO:1903362 44 0.040
positive regulation of cell communication GO:0010647 250 0.040
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.039
regulation of protein catabolic process GO:0042176 55 0.037
cell cycle checkpoint GO:0000075 95 0.037
regulation of immune system process GO:0002682 176 0.037
organonitrogen compound metabolic process GO:1901564 318 0.036
positive regulation of catabolic process GO:0009896 105 0.036
positive regulation of phosphorus metabolic process GO:0010562 139 0.036
regulation of molecular function GO:0065009 217 0.036
regulation of nervous system development GO:0051960 248 0.036
skeletal muscle fiber development GO:0048741 3 0.035
regulation of synapse assembly GO:0051963 94 0.034
synapse assembly GO:0007416 143 0.033
secretion GO:0046903 109 0.033
ion transport GO:0006811 145 0.033
negative regulation of signal transduction GO:0009968 206 0.033
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.033
negative regulation of nervous system development GO:0051961 92 0.033
small molecule metabolic process GO:0044281 305 0.033
sensory organ morphogenesis GO:0090596 260 0.032
response to alcohol GO:0097305 95 0.032
negative regulation of cell communication GO:0010648 223 0.032
epithelial cell development GO:0002064 274 0.031
positive regulation of signaling GO:0023056 243 0.031
muscle cell differentiation GO:0042692 103 0.031
negative regulation of cellular protein metabolic process GO:0032269 85 0.031
columnar cuboidal epithelial cell development GO:0002066 249 0.031
forebrain development GO:0030900 2 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.031
Mouse
regulation of localization GO:0032879 275 0.031
regulation of intracellular transport GO:0032386 64 0.030
cellular protein catabolic process GO:0044257 83 0.030
tissue death GO:0016271 102 0.030
histone h3 k9 acetylation GO:0043970 3 0.030
taxis GO:0042330 304 0.029
negative regulation of defense response GO:0031348 35 0.029
negative regulation of synapse assembly GO:0051964 39 0.029
regulation of ras gtpase activity GO:0032318 38 0.028
hemopoiesis GO:0030097 46 0.028
regulation of phosphorylation GO:0042325 147 0.028
hematopoietic or lymphoid organ development GO:0048534 57 0.027
positive regulation of developmental growth GO:0048639 62 0.027
jak stat cascade GO:0007259 49 0.027
multi organism behavior GO:0051705 175 0.027
peptidyl amino acid modification GO:0018193 105 0.026
macromolecule methylation GO:0043414 45 0.026
organelle fission GO:0048285 340 0.026
Mouse
regulation of purine nucleotide metabolic process GO:1900542 62 0.026
chromatin modification GO:0016568 147 0.026
lateral inhibition GO:0046331 206 0.025
multi organism reproductive behavior GO:0044705 121 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
positive regulation of phosphate metabolic process GO:0045937 139 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.024
endocytosis GO:0006897 310 0.023
mitotic dna damage checkpoint GO:0044773 74 0.023
regulation of catalytic activity GO:0050790 185 0.023
regulation of gtp catabolic process GO:0033124 44 0.023
negative regulation of signaling GO:0023057 219 0.023
nucleoside triphosphate metabolic process GO:0009141 120 0.023
regulation of organelle organization GO:0033043 196 0.022
regulation of proteasomal protein catabolic process GO:0061136 39 0.022
imaginal disc growth GO:0007446 37 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.022
regulation of small gtpase mediated signal transduction GO:0051056 93 0.022
chemical homeostasis GO:0048878 92 0.022
mitotic spindle organization GO:0007052 220 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
imaginal disc derived appendage development GO:0048737 399 0.021
cuticle development GO:0042335 86 0.021
positive regulation of cellular component biogenesis GO:0044089 80 0.021
dna damage checkpoint GO:0000077 78 0.021
autophagy GO:0006914 108 0.021
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
multicellular organismal aging GO:0010259 140 0.020
protein phosphorylation GO:0006468 169 0.020
muscle structure development GO:0061061 224 0.020
ras protein signal transduction GO:0007265 88 0.019
chromatin mediated maintenance of transcription GO:0048096 7 0.019
positive regulation of nucleotide metabolic process GO:0045981 55 0.019
gene silencing by rna GO:0031047 57 0.019
cranial nerve development GO:0021545 1 0.019
regulation of protein localization GO:0032880 76 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
anterior posterior pattern specification GO:0009952 136 0.019
activation of ras gtpase activity GO:0032856 6 0.019
dna packaging GO:0006323 91 0.019
positive regulation of protein catabolic process GO:0045732 34 0.019
regulation of nucleoside metabolic process GO:0009118 50 0.019
cell migration GO:0016477 238 0.019
nucleosome positioning GO:0016584 3 0.019
localization of cell GO:0051674 257 0.018
regulation of protein phosphorylation GO:0001932 64 0.018
nucleosome mobilization GO:0042766 9 0.018
innate immune response GO:0045087 144 0.018
epithelial cell differentiation GO:0030855 322 0.018
regulation of phosphatase activity GO:0010921 3 0.018
segmentation GO:0035282 207 0.018
intracellular transport GO:0046907 228 0.018
peptidyl lysine modification GO:0018205 57 0.018
regulation of response to external stimulus GO:0032101 115 0.018
proteasomal protein catabolic process GO:0010498 59 0.018
cellular response to endogenous stimulus GO:0071495 80 0.017
mitotic sister chromatid segregation GO:0000070 87 0.017
sister chromatid segregation GO:0000819 92 0.017
organ growth GO:0035265 56 0.017
Mouse
regulation of actin cytoskeleton organization GO:0032956 42 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
vesicle mediated transport GO:0016192 381 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
response to ketone GO:1901654 34 0.017
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.017
organic substance transport GO:0071702 257 0.017
cellular macromolecule catabolic process GO:0044265 136 0.017
negative regulation of developmental growth GO:0048640 64 0.017
regulation of proteolysis GO:0030162 87 0.017
actin filament based process GO:0030029 220 0.017
positive regulation of developmental process GO:0051094 143 0.017
regulation of cellular component size GO:0032535 98 0.016
spindle organization GO:0007051 253 0.016
ion transmembrane transport GO:0034220 122 0.016
mitotic nuclear division GO:0007067 213 0.016
regulation of innate immune response GO:0045088 71 0.016
regionalization GO:0003002 416 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
regulation of multicellular organism growth GO:0040014 40 0.016
regulation of synapse structure and activity GO:0050803 128 0.016
positive regulation of growth GO:0045927 75 0.016
ncrna metabolic process GO:0034660 43 0.015
immune system development GO:0002520 57 0.015
dendrite development GO:0016358 204 0.015
negative regulation of notch signaling pathway GO:0045746 41 0.015
positive regulation of multicellular organism growth GO:0040018 21 0.015
negative regulation of neurogenesis GO:0050768 53 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
nuclear division GO:0000280 332 0.015
Mouse
regulation of cytoskeleton organization GO:0051493 89 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
nucleosome organization GO:0034728 59 0.015
cellular response to lipid GO:0071396 20 0.015
covalent chromatin modification GO:0016569 106 0.015
response to acid chemical GO:0001101 25 0.015
cellular response to organic cyclic compound GO:0071407 32 0.015
exocrine system development GO:0035272 162 0.015
chemosensory behavior GO:0007635 106 0.014
regulation of transport GO:0051049 181 0.014
regulation of gene silencing GO:0060968 63 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.014
posttranscriptional gene silencing GO:0016441 46 0.014
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.014
establishment of protein localization GO:0045184 163 0.014
immune response GO:0006955 246 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
positive regulation of nucleoside metabolic process GO:0045979 47 0.014
fatty acid homeostasis GO:0055089 2 0.013
cellular response to ketone GO:1901655 17 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.013
phagocytosis GO:0006909 215 0.013
nucleotide metabolic process GO:0009117 161 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
salivary gland morphogenesis GO:0007435 145 0.013
single organism biosynthetic process GO:0044711 206 0.013
regulation of cell proliferation GO:0042127 163 0.013
pigment metabolic process GO:0042440 84 0.013
protein polymerization GO:0051258 42 0.013
actin cytoskeleton organization GO:0030036 206 0.013
single organism catabolic process GO:0044712 228 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
cellular lipid metabolic process GO:0044255 83 0.013
regulation of cellular response to stress GO:0080135 89 0.013
regulation of cytoplasmic transport GO:1903649 47 0.013
cellular response to hormone stimulus GO:0032870 44 0.013
developmental growth involved in morphogenesis GO:0060560 65 0.013
apoptotic process GO:0006915 159 0.013
cognition GO:0050890 141 0.013
protein ubiquitination GO:0016567 70 0.013
regulation of vesicle mediated transport GO:0060627 59 0.012
mitotic sister chromatid separation GO:0051306 30 0.012
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.012
regulation of hydrolase activity GO:0051336 97 0.012
camera type eye morphogenesis GO:0048593 2 0.012
pigmentation GO:0043473 75 0.012
regulation of cell cycle GO:0051726 291 0.012
larval lymph gland hemopoiesis GO:0035167 17 0.012
defense response GO:0006952 300 0.012
cellular protein complex assembly GO:0043623 71 0.012
axon development GO:0061564 297 0.012
regulation of stem cell proliferation GO:0072091 40 0.012
digestive system development GO:0055123 149 0.012
phosphorylation GO:0016310 294 0.012
regulation of cell cycle g1 s phase transition GO:1902806 23 0.012
regulation of protein polymerization GO:0032271 28 0.012
regulation of cellular localization GO:0060341 136 0.011
macromolecule catabolic process GO:0009057 161 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
single organism intracellular transport GO:1902582 207 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
regulation of gtpase activity GO:0043087 44 0.011
anatomical structure homeostasis GO:0060249 97 0.011
striated muscle cell development GO:0055002 50 0.011
response to wounding GO:0009611 94 0.011
regulation of mitotic sister chromatid segregation GO:0033047 28 0.011
chromatin assembly or disassembly GO:0006333 52 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.011
immune effector process GO:0002252 98 0.011
regulation of glial cell differentiation GO:0045685 1 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.011
positive regulation of transport GO:0051050 92 0.011
developmental programmed cell death GO:0010623 138 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
oviposition GO:0018991 19 0.011
positive regulation of rab gtpase activity GO:0032851 7 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
regulation of epidermal cell differentiation GO:0045604 3 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
macromolecular complex assembly GO:0065003 256 0.010
tor signaling GO:0031929 32 0.010
response to lipopolysaccharide GO:0032496 4 0.010
appendage development GO:0048736 401 0.010

G9a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.077
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
nervous system disease DOID:863 0 0.016