Drosophila melanogaster

34 known processes

unc-13 (Dmel_CG2999)

CG2999 gene product from transcript CG2999-RA

(Aliases: UNC-13-B,CG2999,l(4)ry16,UNC-13,Munc-13/UNC-13,Dunc13,Munc-13,Dunc-13,dUnc-13,Dmel\CG2999,dunc-13,drunc13,dUNC-13,Unc-13,DUNC-13)

unc-13 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
memory GO:0007613 94 0.942
establishment of synaptic vesicle localization GO:0097480 50 0.919
synaptic transmission GO:0007268 288 0.895
neurotransmitter secretion GO:0007269 35 0.816
establishment of localization in cell GO:0051649 402 0.814
chemotaxis GO:0006935 249 0.808
Worm
protein modification process GO:0036211 438 0.795
single organism behavior GO:0044708 391 0.777
positive regulation of multicellular organismal process GO:0051240 143 0.738
locomotory behavior GO:0007626 176 0.669
regulation of cell development GO:0060284 215 0.668
signal release GO:0023061 49 0.667
taxis GO:0042330 304 0.658
Worm
cellular protein modification process GO:0006464 438 0.604
cyclic nucleotide biosynthetic process GO:0009190 25 0.544
chemical homeostasis GO:0048878 92 0.522
golgi to plasma membrane transport GO:0006893 8 0.503
regulation of localization GO:0032879 275 0.495
Mouse Rat
regulation of behavior GO:0050795 75 0.483
Worm
synaptic vesicle transport GO:0048489 50 0.478
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.462
muscle structure development GO:0061061 224 0.437
developmental maturation GO:0021700 172 0.427
Mouse
vesicle mediated transport GO:0016192 381 0.425
establishment of organelle localization GO:0051656 122 0.413
regulation of cellular localization GO:0060341 136 0.411
Mouse Rat
positive regulation of cell migration GO:0030335 2 0.401
positive regulation of macromolecule metabolic process GO:0010604 405 0.386
neuromuscular synaptic transmission GO:0007274 67 0.384
secretion GO:0046903 109 0.371
immune system process GO:0002376 347 0.369
regulation of secretion by cell GO:1903530 39 0.363
Mouse Rat
regulation of neurogenesis GO:0050767 158 0.361
regulation of secretion GO:0051046 44 0.360
Mouse Rat
axon cargo transport GO:0008088 29 0.355
small molecule metabolic process GO:0044281 305 0.348
cellular component assembly involved in morphogenesis GO:0010927 151 0.344
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.339
negative regulation of cellular metabolic process GO:0031324 382 0.339
positive regulation of secretion GO:0051047 22 0.338
Mouse Rat
cell death GO:0008219 279 0.336
organonitrogen compound metabolic process GO:1901564 318 0.332
Mouse
microtubule based transport GO:0010970 42 0.330
regulation of hormone levels GO:0010817 40 0.319
regulation of response to external stimulus GO:0032101 115 0.316
neuron projection guidance GO:0097485 241 0.314
Worm
aging GO:0007568 143 0.313
positive regulation of signaling GO:0023056 243 0.309
Mouse Rat
positive regulation of gene expression GO:0010628 290 0.306
dna metabolic process GO:0006259 227 0.299
axon development GO:0061564 297 0.293
Worm
protein phosphorylation GO:0006468 169 0.292
defense response GO:0006952 300 0.271
circadian rhythm GO:0007623 105 0.269
regulation of immune system process GO:0002682 176 0.267
response to wounding GO:0009611 94 0.266
nucleoside phosphate metabolic process GO:0006753 162 0.260
regulation of endocytosis GO:0030100 37 0.249
organelle localization GO:0051640 148 0.243
regulation of multicellular organismal development GO:2000026 414 0.242
carbohydrate derivative metabolic process GO:1901135 217 0.237
regulation of membrane potential GO:0042391 35 0.235
Rat
regulation of cell differentiation GO:0045595 302 0.235
cell maturation GO:0048469 144 0.235
positive regulation of biosynthetic process GO:0009891 316 0.231
response to abiotic stimulus GO:0009628 341 0.231
positive regulation of cellular component organization GO:0051130 156 0.229
Rat
endocytosis GO:0006897 310 0.224
Mouse
regulation of cellular component movement GO:0051270 42 0.221
positive regulation of transcription dna templated GO:0045893 266 0.220
protein complex biogenesis GO:0070271 201 0.220
Mouse Rat
microtubule based movement GO:0007018 51 0.219
death GO:0016265 284 0.219
homeostatic process GO:0042592 199 0.215
synapse organization GO:0050808 196 0.214
Mouse
apoptotic process GO:0006915 159 0.211
purine ribonucleotide metabolic process GO:0009150 145 0.209
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.205
response to mechanical stimulus GO:0009612 28 0.199
positive regulation of programmed cell death GO:0043068 62 0.198
response to temperature stimulus GO:0009266 106 0.197
protein complex assembly GO:0006461 200 0.194
Mouse Rat
protein localization GO:0008104 284 0.194
regulation of organelle organization GO:0033043 196 0.192
positive regulation of cell motility GO:2000147 3 0.191
regulation of transport GO:0051049 181 0.189
Mouse Rat
negative regulation of response to stimulus GO:0048585 258 0.188
cell proliferation GO:0008283 299 0.187
synaptic vesicle localization GO:0097479 53 0.186
positive regulation of cellular component biogenesis GO:0044089 80 0.185
Rat
mating GO:0007618 120 0.179
negative regulation of biosynthetic process GO:0009890 277 0.175
growth GO:0040007 359 0.174
negative regulation of rna biosynthetic process GO:1902679 240 0.171
positive regulation of cell communication GO:0010647 250 0.168
Mouse Rat
forebrain development GO:0030900 2 0.167
cellular macromolecule localization GO:0070727 220 0.167
monovalent inorganic cation homeostasis GO:0055067 7 0.164
positive regulation of nucleic acid templated transcription GO:1903508 266 0.163
cellular macromolecular complex assembly GO:0034622 153 0.162
Mouse Rat
cellular response to abiotic stimulus GO:0071214 58 0.161
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.160
synaptic vesicle recycling GO:0036465 28 0.160
Mouse
neurotransmitter transport GO:0006836 37 0.158
metal ion homeostasis GO:0055065 44 0.150
chromosome organization GO:0051276 360 0.148
negative regulation of cellular biosynthetic process GO:0031327 277 0.148
single organism intracellular transport GO:1902582 207 0.147
regulation of cell projection organization GO:0031344 92 0.145
feeding behavior GO:0007631 50 0.145
Worm
axonogenesis GO:0007409 290 0.145
Worm
rhythmic process GO:0048511 106 0.144
secretion by cell GO:0032940 101 0.143
phosphorylation GO:0016310 294 0.142
regulation of vesicle mediated transport GO:0060627 59 0.141
Rat
organic cyclic compound catabolic process GO:1901361 168 0.140
nucleotide metabolic process GO:0009117 161 0.140
organic substance catabolic process GO:1901575 308 0.137
positive regulation of transport GO:0051050 92 0.136
Mouse Rat
heterocycle catabolic process GO:0046700 166 0.135
programmed cell death GO:0012501 257 0.132
regulation of phosphate metabolic process GO:0019220 210 0.131
localization of cell GO:0051674 257 0.128
macromolecular complex assembly GO:0065003 256 0.128
Mouse Rat
establishment of vesicle localization GO:0051650 51 0.127
negative regulation of gene expression GO:0010629 387 0.126
negative regulation of multicellular organismal process GO:0051241 142 0.126
response to light stimulus GO:0009416 124 0.126
cellular response to dna damage stimulus GO:0006974 223 0.126
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.126
nucleobase containing small molecule metabolic process GO:0055086 174 0.126
positive regulation of rna biosynthetic process GO:1902680 266 0.125
negative regulation of nucleic acid templated transcription GO:1903507 240 0.123
positive regulation of cellular biosynthetic process GO:0031328 316 0.121
regulation of molecular function GO:0065009 217 0.121
response to organic substance GO:0010033 284 0.121
carboxylic acid metabolic process GO:0019752 92 0.120
regulation of cell migration GO:0030334 22 0.117
regulation of gene expression epigenetic GO:0040029 128 0.117
regulation of locomotion GO:0040012 42 0.115
regulation of catalytic activity GO:0050790 185 0.115
regulation of programmed cell death GO:0043067 152 0.113
establishment of protein localization GO:0045184 163 0.113
positive regulation of cell death GO:0010942 69 0.111
regulation of nervous system development GO:0051960 248 0.110
purine nucleotide metabolic process GO:0006163 146 0.110
catabolic process GO:0009056 409 0.110
immune system development GO:0002520 57 0.109
sensory perception of smell GO:0007608 80 0.108
transcription from rna polymerase ii promoter GO:0006366 368 0.105
regulation of protein kinase activity GO:0045859 51 0.105
protein transport GO:0015031 155 0.104
positive regulation of response to stimulus GO:0048584 323 0.104
ribose phosphate metabolic process GO:0019693 145 0.104
regulation of neurotransmitter levels GO:0001505 38 0.103
regulation of establishment of protein localization GO:0070201 61 0.102
intracellular transport GO:0046907 228 0.101
synaptic vesicle endocytosis GO:0048488 28 0.100
Mouse
nuclear division GO:0000280 332 0.099
regulation of synaptic plasticity GO:0048167 14 0.099
Mouse
sensory perception of chemical stimulus GO:0007606 116 0.098
hemopoiesis GO:0030097 46 0.097
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.097
glycosyl compound catabolic process GO:1901658 112 0.095
response to organic cyclic compound GO:0014070 89 0.095
ion transport GO:0006811 145 0.095
cognition GO:0050890 141 0.094
lipid metabolic process GO:0006629 121 0.093
anatomical structure homeostasis GO:0060249 97 0.093
negative regulation of rna metabolic process GO:0051253 251 0.093
long term memory GO:0007616 62 0.092
regulation of cellular protein metabolic process GO:0032268 243 0.092
camp metabolic process GO:0046058 19 0.092
regulation of phosphorus metabolic process GO:0051174 210 0.090
ribonucleotide metabolic process GO:0009259 145 0.090
positive regulation of cell development GO:0010720 61 0.090
cell projection assembly GO:0030031 94 0.089
purine containing compound metabolic process GO:0072521 155 0.088
muscle cell differentiation GO:0042692 103 0.088
cellular response to organic substance GO:0071310 132 0.086
single organism cellular localization GO:1902580 180 0.086
oocyte axis specification GO:0007309 108 0.085
response to nutrient levels GO:0031667 114 0.085
regulation of response to stress GO:0080134 200 0.085
regulation of cell motility GO:2000145 23 0.084
actomyosin structure organization GO:0031032 56 0.084
positive regulation of secretion by cell GO:1903532 20 0.083
Mouse Rat
positive regulation of protein metabolic process GO:0051247 128 0.083
vesicle localization GO:0051648 55 0.081
dendrite development GO:0016358 204 0.081
biological adhesion GO:0022610 138 0.081
nucleobase containing compound catabolic process GO:0034655 165 0.080
purine containing compound catabolic process GO:0072523 112 0.080
skeletal muscle organ development GO:0060538 48 0.080
regulation of protein serine threonine kinase activity GO:0071900 25 0.079
positive regulation of rna metabolic process GO:0051254 271 0.079
cellular protein localization GO:0034613 160 0.078
regulation of cellular component biogenesis GO:0044087 201 0.076
Rat
ameboidal type cell migration GO:0001667 151 0.075
regulation of cell morphogenesis GO:0022604 163 0.073
neurological system process GO:0050877 358 0.073
neuron neuron synaptic transmission GO:0007270 14 0.072
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.070
cytoskeleton dependent intracellular transport GO:0030705 44 0.070
cellular protein complex disassembly GO:0043624 35 0.070
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.070
hematopoietic or lymphoid organ development GO:0048534 57 0.069
positive regulation of signal transduction GO:0009967 223 0.069
cell motility GO:0048870 251 0.068
oxoacid metabolic process GO:0043436 103 0.068
regulation of protein transport GO:0051223 57 0.068
tissue homeostasis GO:0001894 36 0.067
cell cycle checkpoint GO:0000075 95 0.067
regulation of peptide hormone secretion GO:0090276 5 0.067
regulation of reproductive process GO:2000241 54 0.067
Worm
regulation of synaptic transmission GO:0050804 69 0.066
Mouse Rat
regulation of neuronal synaptic plasticity GO:0048168 8 0.065
Mouse
camp biosynthetic process GO:0006171 17 0.065
regulation of cell cycle GO:0051726 291 0.065
response to oxidative stress GO:0006979 86 0.065
apoptotic signaling pathway GO:0097190 27 0.064
short term memory GO:0007614 19 0.064
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.063
ion homeostasis GO:0050801 55 0.063
synaptic vesicle exocytosis GO:0016079 16 0.062
cellular catabolic process GO:0044248 372 0.062
anterior posterior axis specification embryo GO:0008595 103 0.062
ribonucleoside triphosphate metabolic process GO:0009199 119 0.061
insemination GO:0007320 22 0.061
protein complex disassembly GO:0043241 36 0.061
organic hydroxy compound metabolic process GO:1901615 83 0.060
purine ribonucleoside metabolic process GO:0046128 127 0.060
imaginal disc derived appendage development GO:0048737 399 0.060
cyclic purine nucleotide metabolic process GO:0052652 25 0.060
positive regulation of immune system process GO:0002684 68 0.059
single organism biosynthetic process GO:0044711 206 0.059
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.059
organelle fission GO:0048285 340 0.058
positive regulation of molecular function GO:0044093 136 0.058
organonitrogen compound catabolic process GO:1901565 128 0.058
enzyme linked receptor protein signaling pathway GO:0007167 179 0.058
metal ion transport GO:0030001 74 0.057
phenol containing compound metabolic process GO:0018958 57 0.057
circadian behavior GO:0048512 76 0.057
regulation of protein localization GO:0032880 76 0.057
regulation of protein complex assembly GO:0043254 42 0.057
Rat
nitrogen compound transport GO:0071705 85 0.057
purine nucleoside triphosphate metabolic process GO:0009144 119 0.057
purine nucleoside triphosphate catabolic process GO:0009146 108 0.056
regulation of cell shape GO:0008360 113 0.056
embryo development ending in birth or egg hatching GO:0009792 152 0.056
mitotic nuclear division GO:0007067 213 0.056
epithelial cell development GO:0002064 274 0.056
peptidyl amino acid modification GO:0018193 105 0.056
photoreceptor cell maintenance GO:0045494 11 0.055
aromatic compound catabolic process GO:0019439 166 0.055
leg disc development GO:0035218 92 0.055
transmembrane transport GO:0055085 139 0.054
regulation of cell death GO:0010941 173 0.054
embryonic pattern specification GO:0009880 174 0.053
positive regulation of phosphorus metabolic process GO:0010562 139 0.053
response to oxygen containing compound GO:1901700 200 0.053
locomotor rhythm GO:0045475 56 0.052
mrna metabolic process GO:0016071 124 0.052
cation homeostasis GO:0055080 51 0.052
cell adhesion GO:0007155 136 0.052
intracellular protein transport GO:0006886 104 0.052
membrane organization GO:0061024 112 0.051
dopamine receptor signaling pathway GO:0007212 4 0.050
regulation of multi organism process GO:0043900 131 0.050
Worm
multi organism reproductive behavior GO:0044705 121 0.050
Worm
purine nucleoside metabolic process GO:0042278 127 0.050
organic substance transport GO:0071702 257 0.050
covalent chromatin modification GO:0016569 106 0.050
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.050
positive regulation of protein modification process GO:0031401 58 0.049
cellular ion homeostasis GO:0006873 39 0.049
regulation of protein phosphorylation GO:0001932 64 0.049
positive regulation of cell differentiation GO:0045597 64 0.048
purine nucleoside monophosphate metabolic process GO:0009126 50 0.048
developmental growth GO:0048589 280 0.048
regulation of peptide secretion GO:0002791 6 0.048
adult behavior GO:0030534 137 0.047
organophosphate catabolic process GO:0046434 112 0.047
rna localization GO:0006403 115 0.047
regulation of anatomical structure morphogenesis GO:0022603 242 0.047
organelle assembly GO:0070925 198 0.047
body morphogenesis GO:0010171 2 0.047
wound healing GO:0042060 75 0.047
regulation of neuron differentiation GO:0045664 103 0.046
positive regulation of organelle organization GO:0010638 65 0.046
cellular component disassembly GO:0022411 46 0.046
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.046
chorion containing eggshell formation GO:0007304 105 0.045
regulation of apoptotic process GO:0042981 130 0.045
cell migration GO:0016477 238 0.045
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.045
inorganic ion transmembrane transport GO:0098660 73 0.045
macromolecular complex disassembly GO:0032984 37 0.044
actin cytoskeleton organization GO:0030036 206 0.044
meiotic nuclear division GO:0007126 151 0.044
pigmentation GO:0043473 75 0.043
ribonucleoside metabolic process GO:0009119 127 0.043
positive regulation of synaptic transmission GO:0050806 15 0.043
Mouse Rat
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.043
hormone secretion GO:0046879 7 0.043
cellular protein complex assembly GO:0043623 71 0.043
Mouse Rat
negative regulation of transcription dna templated GO:0045892 237 0.043
exocytosis GO:0006887 28 0.042
cell division GO:0051301 248 0.042
response to alcohol GO:0097305 95 0.042
reproductive behavior GO:0019098 122 0.042
Worm
regulation of insulin secretion GO:0050796 5 0.041
regulation of synapse organization GO:0050807 110 0.041
macromolecule catabolic process GO:0009057 161 0.041
regulation of epithelial cell proliferation GO:0050678 4 0.040
positive regulation of protein phosphorylation GO:0001934 34 0.040
spinal cord development GO:0021510 1 0.039
segmentation GO:0035282 207 0.039
positive regulation of cgmp biosynthetic process GO:0030828 1 0.039
positive regulation of intracellular signal transduction GO:1902533 116 0.039
oocyte differentiation GO:0009994 145 0.039
cgmp biosynthetic process GO:0006182 8 0.039
amine metabolic process GO:0009308 12 0.038
response to heat GO:0009408 63 0.038
epithelial cell differentiation GO:0030855 322 0.038
regulation of cellular response to stress GO:0080135 89 0.037
positive regulation of developmental process GO:0051094 143 0.037
blastoderm segmentation GO:0007350 159 0.037
multicellular organismal homeostasis GO:0048871 41 0.037
heart process GO:0003015 37 0.037
response to radiation GO:0009314 155 0.036
organophosphate metabolic process GO:0019637 195 0.036
multi organism behavior GO:0051705 175 0.036
Worm
leg disc morphogenesis GO:0007478 80 0.036
nucleoside triphosphate metabolic process GO:0009141 120 0.036
tissue morphogenesis GO:0048729 297 0.036
cellular chemical homeostasis GO:0055082 40 0.036
purine ribonucleoside catabolic process GO:0046130 112 0.035
detection of chemical stimulus GO:0009593 93 0.035
negative regulation of molecular function GO:0044092 51 0.035
golgi to plasma membrane protein transport GO:0043001 8 0.035
cyclic nucleotide metabolic process GO:0009187 28 0.035
response to glucose GO:0009749 2 0.035
regulation of cell adhesion GO:0030155 27 0.035
regulation of protein complex disassembly GO:0043244 29 0.034
nucleoside monophosphate catabolic process GO:0009125 39 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.034
cytoplasmic transport GO:0016482 130 0.034
phagocytosis GO:0006909 215 0.034
spermatogenesis GO:0007283 200 0.034
nucleotide catabolic process GO:0009166 109 0.033
cell growth GO:0016049 108 0.033
intracellular signal transduction GO:0035556 300 0.033
carbohydrate metabolic process GO:0005975 82 0.033
regulation of intracellular signal transduction GO:1902531 236 0.033
negative regulation of nervous system development GO:0051961 92 0.033
regulation of pole plasm oskar mrna localization GO:0007317 27 0.033
regulation of nucleotide metabolic process GO:0006140 62 0.032
negative regulation of programmed cell death GO:0043069 72 0.032
eggshell formation GO:0030703 105 0.032
ribonucleoside triphosphate catabolic process GO:0009203 108 0.032
carbohydrate derivative catabolic process GO:1901136 118 0.032
chromatin modification GO:0016568 147 0.032
positive regulation of locomotion GO:0040017 8 0.032
regulation of hydrolase activity GO:0051336 97 0.032
tripartite regional subdivision GO:0007351 103 0.032
positive regulation of phosphate metabolic process GO:0045937 139 0.032
hindbrain development GO:0030902 2 0.032
dna damage checkpoint GO:0000077 78 0.032
response to reactive oxygen species GO:0000302 24 0.031
negative regulation of endopeptidase activity GO:0010951 11 0.031
positive regulation of cellular protein metabolic process GO:0032270 118 0.031
rna processing GO:0006396 147 0.031
actin filament based process GO:0030029 220 0.031
substrate adhesion dependent cell spreading GO:0034446 2 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.031
negative regulation of signaling GO:0023057 219 0.030
imaginal disc derived leg morphogenesis GO:0007480 80 0.030
glycosyl compound metabolic process GO:1901657 127 0.030
organic acid metabolic process GO:0006082 103 0.030
heart contraction GO:0060047 26 0.030
negative regulation of cell communication GO:0010648 223 0.030
carbohydrate derivative biosynthetic process GO:1901137 85 0.030
cellular lipid metabolic process GO:0044255 83 0.029
compound eye retinal cell programmed cell death GO:0046667 23 0.029
ribonucleotide catabolic process GO:0009261 109 0.029
regulation of system process GO:0044057 36 0.029
embryonic development via the syncytial blastoderm GO:0001700 148 0.029
myofibril assembly GO:0030239 36 0.029
nucleoside phosphate biosynthetic process GO:1901293 34 0.029
morphogenesis of an epithelium GO:0002009 276 0.029
purine ribonucleotide catabolic process GO:0009154 109 0.029
defense response to other organism GO:0098542 225 0.029
myotube cell development GO:0014904 3 0.029
wnt signaling pathway GO:0016055 98 0.029
sarcomere organization GO:0045214 26 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.028
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.028
neuron maturation GO:0042551 31 0.028
cellular response to oxidative stress GO:0034599 28 0.028
detection of light stimulus GO:0009583 58 0.028
regulation of growth GO:0040008 233 0.028
neuronal action potential GO:0019228 10 0.028
regulation of cytoplasmic transport GO:1903649 47 0.028
response to endogenous stimulus GO:0009719 119 0.028
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.028
oocyte anterior posterior axis specification GO:0007314 72 0.027
cellular response to external stimulus GO:0071496 66 0.027
negative regulation of cell development GO:0010721 62 0.027
regulation of meiosis GO:0040020 3 0.027
regionalization GO:0003002 416 0.027
histone modification GO:0016570 106 0.027
positive regulation of cellular component movement GO:0051272 11 0.027
purine nucleotide catabolic process GO:0006195 109 0.026
negative regulation of cell differentiation GO:0045596 143 0.026
regulation of protein metabolic process GO:0051246 256 0.026
intracellular mrna localization GO:0008298 66 0.026
cation transport GO:0006812 110 0.026
cellular amine metabolic process GO:0044106 12 0.026
anion transport GO:0006820 41 0.026
dna packaging GO:0006323 91 0.026
camera type eye development GO:0043010 4 0.026
anterior posterior axis specification GO:0009948 109 0.026
nucleoside phosphate catabolic process GO:1901292 110 0.026
positive regulation of catalytic activity GO:0043085 118 0.026
nucleoside metabolic process GO:0009116 127 0.026
regulation of cytoskeleton organization GO:0051493 89 0.026
regulation of bmp signaling pathway GO:0030510 23 0.025
peptide hormone secretion GO:0030072 5 0.025
nucleoside monophosphate metabolic process GO:0009123 52 0.025
negative regulation of cell death GO:0060548 81 0.025
single organism catabolic process GO:0044712 228 0.025
cellular nitrogen compound catabolic process GO:0044270 165 0.025
response to carbon dioxide GO:0010037 4 0.025
ribose phosphate biosynthetic process GO:0046390 28 0.025
response to starvation GO:0042594 97 0.025
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.025
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.025
determination of adult lifespan GO:0008340 137 0.025
positive regulation of protein transport GO:0051222 37 0.025
positive regulation of transferase activity GO:0051347 26 0.024
multi multicellular organism process GO:0044706 123 0.024
Worm
mitochondrion organization GO:0007005 65 0.024
positive regulation of protein kinase activity GO:0045860 25 0.024
peptidyl threonine phosphorylation GO:0018107 2 0.024
positive regulation of kinase activity GO:0033674 25 0.024
positive regulation of mapk cascade GO:0043410 63 0.024
negative regulation of cell cycle GO:0045786 116 0.024
cellular response to carbon dioxide GO:0071244 2 0.024
axis specification GO:0009798 167 0.024
fertilization GO:0009566 26 0.024
response to decreased oxygen levels GO:0036293 58 0.024
divalent inorganic cation transport GO:0072511 30 0.024
response to inorganic substance GO:0010035 44 0.024
positive regulation of protein complex assembly GO:0031334 22 0.023
Rat
positive regulation of intracellular protein transport GO:0090316 30 0.023
anterior posterior pattern specification GO:0009952 136 0.023
negative regulation of signal transduction GO:0009968 206 0.023
dna integrity checkpoint GO:0031570 81 0.023
purine containing compound biosynthetic process GO:0072522 30 0.023
regulation of intracellular protein transport GO:0033157 46 0.023
telencephalon development GO:0021537 2 0.022
regulation of dna metabolic process GO:0051052 34 0.022
single organismal cell cell adhesion GO:0016337 45 0.022
nucleoside catabolic process GO:0009164 112 0.022
epithelial cell migration GO:0010631 148 0.022
adult walking behavior GO:0007628 9 0.022
dna repair GO:0006281 54 0.022
vesicle organization GO:0016050 44 0.022
Mouse
axon guidance GO:0007411 233 0.021
Worm
tube development GO:0035295 244 0.021
regulation of cell substrate adhesion GO:0010810 2 0.021
protein targeting GO:0006605 64 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
immune response regulating signaling pathway GO:0002764 2 0.021
regulation of neurotransmitter secretion GO:0046928 14 0.021
Mouse Rat
positive regulation of gtp catabolic process GO:0033126 43 0.021
response to monosaccharide GO:0034284 4 0.021
central nervous system development GO:0007417 201 0.021
negative regulation of cellular component organization GO:0051129 108 0.021
regulation of rna splicing GO:0043484 69 0.021
positive regulation of phosphorylation GO:0042327 87 0.021
striated muscle cell differentiation GO:0051146 90 0.021
macroautophagy GO:0016236 42 0.020
dephosphorylation GO:0016311 51 0.020
ion transmembrane transport GO:0034220 122 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.020
embryonic axis specification GO:0000578 107 0.020
protein catabolic process GO:0030163 101 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
negative regulation of insulin receptor signaling pathway GO:0046627 11 0.020
male gamete generation GO:0048232 201 0.020
dna replication GO:0006260 48 0.020

unc-13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.146
cancer DOID:162 0 0.093
disease of cellular proliferation DOID:14566 0 0.093
organ system cancer DOID:0050686 0 0.048
nervous system disease DOID:863 0 0.041