Drosophila melanogaster

140 known processes

mof (Dmel_CG3025)

males absent on the first

(Aliases: dMOF,max,dmMOF,Mof,Dmel\CG3025,CG3025,MOF)

mof biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone h4 k16 acetylation GO:0043984 4 0.961
peptidyl lysine modification GO:0018205 57 0.898
chromatin modification GO:0016568 147 0.892
regulation of gene expression epigenetic GO:0040029 128 0.803
histone modification GO:0016570 106 0.797
chromosome organization GO:0051276 360 0.741
internal protein amino acid acetylation GO:0006475 38 0.721
protein acylation GO:0043543 42 0.705
organelle fission GO:0048285 340 0.702
negative regulation of gene expression GO:0010629 387 0.666
Human
covalent chromatin modification GO:0016569 106 0.662
cellular response to dna damage stimulus GO:0006974 223 0.655
peptidyl lysine acetylation GO:0018394 39 0.647
chromatin organization GO:0006325 207 0.635
protein acetylation GO:0006473 39 0.618
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.532
Human
response to organic substance GO:0010033 284 0.474
growth GO:0040007 359 0.472
gene silencing GO:0016458 138 0.442
negative regulation of cellular biosynthetic process GO:0031327 277 0.427
Human
nuclear division GO:0000280 332 0.397
regulation of chromatin modification GO:1903308 28 0.392
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.381
Human
chromatin silencing GO:0006342 76 0.366
negative regulation of cellular metabolic process GO:0031324 382 0.361
Human
protein modification process GO:0036211 438 0.348
histone h4 acetylation GO:0043967 13 0.330
negative regulation of nucleic acid templated transcription GO:1903507 240 0.323
Human
cellular protein modification process GO:0006464 438 0.315
dna repair GO:0006281 54 0.305
eye development GO:0001654 323 0.297
response to abiotic stimulus GO:0009628 341 0.292
protein modification by small protein conjugation GO:0032446 79 0.291
regulation of growth GO:0040008 233 0.285
chromatin assembly GO:0031497 48 0.276
meiotic nuclear division GO:0007126 151 0.238
peptidyl amino acid modification GO:0018193 105 0.228
protein modification by small protein conjugation or removal GO:0070647 106 0.223
response to extracellular stimulus GO:0009991 116 0.219
cellular response to extracellular stimulus GO:0031668 64 0.214
small molecule metabolic process GO:0044281 305 0.203
positive regulation of macromolecule metabolic process GO:0010604 405 0.200
Human
single organism biosynthetic process GO:0044711 206 0.191
lipid metabolic process GO:0006629 121 0.185
chromatin remodeling GO:0006338 72 0.175
Fly
aging GO:0007568 143 0.170
dna metabolic process GO:0006259 227 0.167
cellular response to chemical stimulus GO:0070887 199 0.164
negative regulation of biosynthetic process GO:0009890 277 0.151
Human
sensory perception GO:0007600 196 0.151
lipid biosynthetic process GO:0008610 46 0.150
regulation of chromosome organization GO:0033044 64 0.149
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.146
Human
negative regulation of response to oxidative stress GO:1902883 1 0.145
cell growth GO:0016049 108 0.142
reproductive system development GO:0061458 74 0.139
negative regulation of rna biosynthetic process GO:1902679 240 0.132
Human
organic acid metabolic process GO:0006082 103 0.129
heterochromatin organization GO:0070828 25 0.122
regionalization GO:0003002 416 0.122
regulation of mitotic cell cycle GO:0007346 190 0.119
response to radiation GO:0009314 155 0.117
negative regulation of gene expression epigenetic GO:0045814 77 0.114
chromatin assembly or disassembly GO:0006333 52 0.114
regulation of response to stress GO:0080134 200 0.113
determination of adult lifespan GO:0008340 137 0.113
protein ubiquitination GO:0016567 70 0.112
mitotic nuclear division GO:0007067 213 0.105
dna conformation change GO:0071103 105 0.097
negative regulation of chromatin silencing GO:0031936 9 0.096
positive regulation of nucleic acid templated transcription GO:1903508 266 0.096
Human
developmental growth GO:0048589 280 0.095
negative regulation of rna metabolic process GO:0051253 251 0.094
Human
pigmentation GO:0043473 75 0.093
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.091
Human
fertilization GO:0009566 26 0.090
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.090
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.087
Human
internal peptidyl lysine acetylation GO:0018393 38 0.085
cell cycle checkpoint GO:0000075 95 0.082
regulation of phosphate metabolic process GO:0019220 210 0.080
histone acetylation GO:0016573 38 0.080
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.079
multicellular organismal aging GO:0010259 140 0.075
amine metabolic process GO:0009308 12 0.074
enzyme linked receptor protein signaling pathway GO:0007167 179 0.074
regulation of dna metabolic process GO:0051052 34 0.073
neurological system process GO:0050877 358 0.073
regulation of protein modification process GO:0031399 112 0.072
regulation of cell cycle process GO:0010564 181 0.071
regulation of molecular function GO:0065009 217 0.071
maintenance of location GO:0051235 73 0.071
positive regulation of response to stimulus GO:0048584 323 0.070
regulation of cell proliferation GO:0042127 163 0.069
organelle localization GO:0051640 148 0.068
regulation of protein metabolic process GO:0051246 256 0.067
negative regulation of transcription dna templated GO:0045892 237 0.067
Human
negative regulation of growth GO:0045926 84 0.065
meiotic cell cycle process GO:1903046 132 0.065
developmental pigmentation GO:0048066 68 0.064
regulation of catabolic process GO:0009894 170 0.063
Human
chemical homeostasis GO:0048878 92 0.063
positive regulation of cellular component organization GO:0051130 156 0.062
response to organic cyclic compound GO:0014070 89 0.062
double strand break repair GO:0006302 26 0.062
multicellular organism growth GO:0035264 46 0.062
cell death GO:0008219 279 0.062
cellular lipid metabolic process GO:0044255 83 0.062
positive regulation of rna metabolic process GO:0051254 271 0.062
Human
response to oxygen containing compound GO:1901700 200 0.060
positive regulation of biosynthetic process GO:0009891 316 0.059
Human
meiotic cell cycle GO:0051321 171 0.058
cellular macromolecule localization GO:0070727 220 0.058
Worm
regulation of immune system process GO:0002682 176 0.058
compound eye development GO:0048749 307 0.057
organic substance catabolic process GO:1901575 308 0.056
cellular catabolic process GO:0044248 372 0.056
Human
catabolic process GO:0009056 409 0.056
Human
cellular response to external stimulus GO:0071496 66 0.055
positive regulation of signaling GO:0023056 243 0.055
respiratory system development GO:0060541 213 0.054
regulation of cellular amino acid metabolic process GO:0006521 0 0.054
negative regulation of cell cycle process GO:0010948 109 0.053
brain development GO:0007420 120 0.053
regulation of chromatin silencing GO:0031935 36 0.053
response to endogenous stimulus GO:0009719 119 0.053
ion homeostasis GO:0050801 55 0.052
positive regulation of transcription dna templated GO:0045893 266 0.052
Human
endocytosis GO:0006897 310 0.051
regulation of cellular amine metabolic process GO:0033238 3 0.050
sex differentiation GO:0007548 81 0.049
cell proliferation GO:0008283 299 0.049
dosage compensation GO:0007549 16 0.049
homeostatic process GO:0042592 199 0.049
regulation of cell death GO:0010941 173 0.048
cellular response to organic substance GO:0071310 132 0.048
lipid localization GO:0010876 54 0.048
eye pigment metabolic process GO:0042441 33 0.048
regulation of intracellular signal transduction GO:1902531 236 0.047
modification dependent macromolecule catabolic process GO:0043632 79 0.046
single organism catabolic process GO:0044712 228 0.046
vesicle mediated transport GO:0016192 381 0.045
embryonic organ development GO:0048568 50 0.045
epithelial tube morphogenesis GO:0060562 88 0.045
carboxylic acid metabolic process GO:0019752 92 0.044
ubiquitin dependent protein catabolic process GO:0006511 78 0.043
response to heat GO:0009408 63 0.043
regulation of chromatin organization GO:1902275 32 0.042
positive regulation of intracellular signal transduction GO:1902533 116 0.042
regulation of cellular response to stress GO:0080135 89 0.042
negative regulation of cellular response to oxidative stress GO:1900408 1 0.041
reproductive structure development GO:0048608 74 0.041
death GO:0016265 284 0.040
regulation of meiosis GO:0040020 3 0.040
heterocycle catabolic process GO:0046700 166 0.040
regulation of phosphorus metabolic process GO:0051174 210 0.040
regulation of transport GO:0051049 181 0.040
eye morphogenesis GO:0048592 260 0.039
establishment of localization in cell GO:0051649 402 0.039
response to nutrient levels GO:0031667 114 0.038
gliogenesis GO:0042063 80 0.038
mitotic cell cycle phase transition GO:0044772 138 0.037
columnar cuboidal epithelial cell development GO:0002066 249 0.037
immune system process GO:0002376 347 0.037
Human
spindle organization GO:0007051 253 0.037
appendage development GO:0048736 401 0.036
regulation of cellular catabolic process GO:0031329 157 0.036
Human
cellular ketone metabolic process GO:0042180 24 0.036
larval development GO:0002164 104 0.035
dna biosynthetic process GO:0071897 24 0.035
regulation of phosphorylation GO:0042325 147 0.034
gene silencing by rna GO:0031047 57 0.034
embryo development ending in birth or egg hatching GO:0009792 152 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.034
cell aging GO:0007569 2 0.034
regulation of gene silencing GO:0060968 63 0.034
positive regulation of cell communication GO:0010647 250 0.034
negative regulation of cell cycle phase transition GO:1901988 103 0.033
oxoacid metabolic process GO:0043436 103 0.033
regulation of cellular ketone metabolic process GO:0010565 3 0.033
defense response GO:0006952 300 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.032
Human
programmed cell death GO:0012501 257 0.032
response to nitrogen compound GO:1901698 90 0.031
mitotic sister chromatid segregation GO:0000070 87 0.031
positive regulation of cellular protein metabolic process GO:0032270 118 0.031
modification dependent protein catabolic process GO:0019941 78 0.031
intracellular protein transport GO:0006886 104 0.031
mitotic cytokinesis GO:0000281 50 0.030
cellular amine metabolic process GO:0044106 12 0.030
phosphorylation GO:0016310 294 0.029
regulation of nervous system development GO:0051960 248 0.028
response to organophosphorus GO:0046683 2 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
heterochromatin assembly GO:0031507 13 0.028
intracellular transport GO:0046907 228 0.027
connective tissue development GO:0061448 3 0.027
positive regulation of signal transduction GO:0009967 223 0.027
proteolysis GO:0006508 192 0.026
sister chromatid segregation GO:0000819 92 0.026
dna packaging GO:0006323 91 0.026
regulation of neuron differentiation GO:0045664 103 0.026
cell cycle phase transition GO:0044770 140 0.026
cellular protein catabolic process GO:0044257 83 0.026
smoothened signaling pathway GO:0007224 49 0.026
signal transduction in response to dna damage GO:0042770 3 0.026
response to wounding GO:0009611 94 0.025
tube development GO:0035295 244 0.025
cellular macromolecule catabolic process GO:0044265 136 0.025
regulation of localization GO:0032879 275 0.025
border follicle cell migration GO:0007298 113 0.025
regulation of behavior GO:0050795 75 0.025
positive regulation of transport GO:0051050 92 0.024
glial cell differentiation GO:0010001 35 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.024
gonad development GO:0008406 50 0.024
morphogenesis of a branching epithelium GO:0061138 45 0.023
negative regulation of protein metabolic process GO:0051248 85 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
glial cell development GO:0021782 27 0.023
regulation of response to dna damage stimulus GO:2001020 23 0.023
regulation of organelle organization GO:0033043 196 0.023
cell division GO:0051301 248 0.023
regulation of developmental growth GO:0048638 174 0.022
regulation of cell cycle phase transition GO:1901987 130 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
response to hexose GO:0009746 3 0.022
positive regulation of gene expression GO:0010628 290 0.022
Human
bmp signaling pathway GO:0030509 27 0.022
regulation of neurogenesis GO:0050767 158 0.022
regulation of response to oxidative stress GO:1902882 4 0.022
sensory organ morphogenesis GO:0090596 260 0.022
regulation of cell division GO:0051302 72 0.021
positive regulation of gene expression epigenetic GO:0045815 16 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.021
Human
protein phosphorylation GO:0006468 169 0.021
negative regulation of multicellular organismal process GO:0051241 142 0.021
cellular response to radiation GO:0071478 52 0.021
negative regulation of cell death GO:0060548 81 0.020
central nervous system development GO:0007417 201 0.020
organic substance transport GO:0071702 257 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.020
mitotic cell cycle checkpoint GO:0007093 88 0.020
negative regulation of mitotic cell cycle GO:0045930 109 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.020
cellular protein localization GO:0034613 160 0.019
Worm
regulation of nuclear division GO:0051783 58 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
positive regulation of molecular function GO:0044093 136 0.019
cellular response to peptide GO:1901653 28 0.019
negative regulation of nervous system development GO:0051961 92 0.018
single organism cellular localization GO:1902580 180 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
regulation of cell cycle GO:0051726 291 0.018
mitotic spindle organization GO:0007052 220 0.018
chemosensory behavior GO:0007635 106 0.018
protein localization GO:0008104 284 0.018
Worm
immune system development GO:0002520 57 0.018
Human
protein catabolic process GO:0030163 101 0.017
mitotic g2 m transition checkpoint GO:0044818 70 0.017
dna alkylation GO:0006305 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
ribonucleotide metabolic process GO:0009259 145 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
morphogenesis of a branching structure GO:0001763 45 0.016
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.016
single organism intracellular transport GO:1902582 207 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
positive regulation of phosphorylation GO:0042327 87 0.016
positive regulation of protein modification process GO:0031401 58 0.016
positive regulation of organelle organization GO:0010638 65 0.016
development of primary sexual characteristics GO:0045137 50 0.016
positive regulation of protein transport GO:0051222 37 0.016
taxis GO:0042330 304 0.016
negative regulation of cell cycle GO:0045786 116 0.016
chromosome segregation GO:0007059 157 0.016
carbohydrate homeostasis GO:0033500 12 0.015
macromolecule catabolic process GO:0009057 161 0.015
regulation of cellular response to oxidative stress GO:1900407 4 0.015
regulation of cell development GO:0060284 215 0.015
cellular response to starvation GO:0009267 61 0.015
regulation of autophagy GO:0010506 62 0.015
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.015
regulation of bmp signaling pathway GO:0030510 23 0.015
regulation of transferase activity GO:0051338 58 0.015
intracellular signal transduction GO:0035556 300 0.015
dna integrity checkpoint GO:0031570 81 0.015
nucleosome positioning GO:0016584 3 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
cellular homeostasis GO:0019725 80 0.015
heart development GO:0007507 82 0.015
pigment metabolic process involved in pigmentation GO:0043474 33 0.015
regulation of catalytic activity GO:0050790 185 0.015
regulation of hormone levels GO:0010817 40 0.015
negative regulation of phosphate metabolic process GO:0045936 45 0.014
nucleosome organization GO:0034728 59 0.014
Fly
response to alcohol GO:0097305 95 0.014
autophagy GO:0006914 108 0.014
Human
branching morphogenesis of an epithelial tube GO:0048754 45 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
anatomical structure homeostasis GO:0060249 97 0.014
response to temperature stimulus GO:0009266 106 0.014
regulation of cell growth GO:0001558 43 0.014
negative regulation of cell communication GO:0010648 223 0.014
mating behavior GO:0007617 106 0.014
regulation of response to external stimulus GO:0032101 115 0.014
regulation of chromatin assembly GO:0010847 9 0.014
chromosome separation GO:0051304 42 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
rna localization GO:0006403 115 0.013
aromatic compound catabolic process GO:0019439 166 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
regulation of kinase activity GO:0043549 53 0.013
notch signaling pathway GO:0007219 120 0.013
regulation of transcription by chromatin organization GO:0034401 3 0.013
cellular response to organic cyclic compound GO:0071407 32 0.013
positive regulation of growth GO:0045927 75 0.013
negative regulation of catalytic activity GO:0043086 42 0.013
single organism nuclear import GO:1902593 51 0.012
regulation of histone modification GO:0031056 20 0.012
cardiovascular system development GO:0072358 82 0.012
response to ionizing radiation GO:0010212 32 0.012
cellular response to oxidative stress GO:0034599 28 0.012
ovarian follicle cell development GO:0030707 248 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
macromolecular complex assembly GO:0065003 256 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
establishment of protein localization GO:0045184 163 0.012
pigment cell differentiation GO:0050931 3 0.012
reproductive behavior GO:0019098 122 0.012
regulation of protein kinase activity GO:0045859 51 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
compound eye morphogenesis GO:0001745 249 0.012
learning GO:0007612 75 0.012
response to hypoxia GO:0001666 53 0.011
mating GO:0007618 120 0.011
protein complex biogenesis GO:0070271 201 0.011
negative regulation of developmental process GO:0051093 201 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
stress activated protein kinase signaling cascade GO:0031098 55 0.011
regulation of intracellular protein transport GO:0033157 46 0.011
monocarboxylic acid metabolic process GO:0032787 29 0.011
dna damage checkpoint GO:0000077 78 0.011
body morphogenesis GO:0010171 2 0.011
positive regulation of catabolic process GO:0009896 105 0.011
leg disc morphogenesis GO:0007478 80 0.011
epithelial cell development GO:0002064 274 0.011
nucleosome mobilization GO:0042766 9 0.011
eye pigment biosynthetic process GO:0006726 32 0.011
developmental programmed cell death GO:0010623 138 0.011
fatty acid metabolic process GO:0006631 20 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
multi organism behavior GO:0051705 175 0.011
epidermis development GO:0008544 65 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
response to oxidative stress GO:0006979 86 0.010
limb development GO:0060173 1 0.010
regulation of cell differentiation GO:0045595 302 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
imaginal disc derived appendage development GO:0048737 399 0.010
head development GO:0060322 135 0.010
divalent inorganic cation homeostasis GO:0072507 29 0.010
negative regulation of bmp signaling pathway GO:0030514 12 0.010

mof disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024