Drosophila melanogaster

67 known processes

Ino80 (Dmel_CG31212)

CG31212 gene product from transcript CG31212-RA

(Aliases: CG3602,dINO80,CG18491,Dmel\CG31212,CG31212,CG14279)

Ino80 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.947
Human Yeast
regulation of microtubule cytoskeleton organization GO:0070507 41 0.656
small molecule metabolic process GO:0044281 305 0.492
Human Yeast
histone acetylation GO:0016573 38 0.407
positive regulation of protein metabolic process GO:0051247 128 0.376
regulation of organelle organization GO:0033043 196 0.349
regulation of anatomical structure morphogenesis GO:0022603 242 0.294
negative regulation of response to stimulus GO:0048585 258 0.283
regulation of mitotic cell cycle GO:0007346 190 0.276
Human
regulation of microtubule based process GO:0032886 49 0.275
endocytosis GO:0006897 310 0.266
regulation of cell death GO:0010941 173 0.265
regulation of cytoskeleton organization GO:0051493 89 0.243
establishment of localization in cell GO:0051649 402 0.195
cell migration GO:0016477 238 0.190
mitotic nuclear division GO:0007067 213 0.187
Human
appendage development GO:0048736 401 0.187
morphogenesis of an epithelium GO:0002009 276 0.186
taxis GO:0042330 304 0.173
organelle fission GO:0048285 340 0.173
Human
axon guidance GO:0007411 233 0.163
carboxylic acid metabolic process GO:0019752 92 0.161
chromosome segregation GO:0007059 157 0.157
Human Yeast
columnar cuboidal epithelial cell development GO:0002066 249 0.147
regulation of cellular amino acid metabolic process GO:0006521 0 0.145
internal protein amino acid acetylation GO:0006475 38 0.145
regulation of cellular ketone metabolic process GO:0010565 3 0.144
protein modification process GO:0036211 438 0.143
negative regulation of nucleic acid templated transcription GO:1903507 240 0.141
chemotaxis GO:0006935 249 0.138
eggshell formation GO:0030703 105 0.136
developmental programmed cell death GO:0010623 138 0.134
regulation of cell cycle GO:0051726 291 0.134
Human
cellular component assembly involved in morphogenesis GO:0010927 151 0.134
regulation of cell morphogenesis GO:0022604 163 0.134
regulation of chromosome organization GO:0033044 64 0.132
regulation of mitotic cell cycle phase transition GO:1901990 130 0.124
Human
protein acetylation GO:0006473 39 0.122
negative regulation of rna biosynthetic process GO:1902679 240 0.117
chromatin organization GO:0006325 207 0.114
Human Yeast
sister chromatid segregation GO:0000819 92 0.113
Human
oxoacid metabolic process GO:0043436 103 0.111
cellular ketone metabolic process GO:0042180 24 0.110
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.110
anterior posterior pattern specification GO:0009952 136 0.104
gene silencing GO:0016458 138 0.103
Yeast
positive regulation of cellular amine metabolic process GO:0033240 0 0.102
covalent chromatin modification GO:0016569 106 0.101
regulation of programmed cell death GO:0043067 152 0.099
cellular protein modification process GO:0006464 438 0.098
salivary gland morphogenesis GO:0007435 145 0.097
positive regulation of gene expression GO:0010628 290 0.097
Human Yeast
protein complex assembly GO:0006461 200 0.096
Human
positive regulation of cellular component organization GO:0051130 156 0.095
negative regulation of cell death GO:0060548 81 0.095
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.094
cell cycle phase transition GO:0044770 140 0.094
Human
imaginal disc derived appendage morphogenesis GO:0035114 395 0.094
negative regulation of cellular component organization GO:0051129 108 0.092
regulation of cell cycle process GO:0010564 181 0.089
Human
cellular amino acid metabolic process GO:0006520 61 0.086
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.086
mitotic spindle organization GO:0007052 220 0.085
muscle structure development GO:0061061 224 0.085
cellular amine metabolic process GO:0044106 12 0.081
embryonic development via the syncytial blastoderm GO:0001700 148 0.080
protein acylation GO:0043543 42 0.078
regulation of cell differentiation GO:0045595 302 0.078
segmentation GO:0035282 207 0.078
epithelial cell development GO:0002064 274 0.077
methylation GO:0032259 47 0.077
ovarian follicle cell development GO:0030707 248 0.076
negative regulation of cellular biosynthetic process GO:0031327 277 0.075
protein catabolic process GO:0030163 101 0.075
connective tissue development GO:0061448 3 0.074
negative regulation of rna metabolic process GO:0051253 251 0.074
axonogenesis GO:0007409 290 0.073
modification dependent protein catabolic process GO:0019941 78 0.072
nurse cell apoptotic process GO:0045476 17 0.071
proteolysis GO:0006508 192 0.068
imaginal disc derived appendage development GO:0048737 399 0.065
dendrite morphogenesis GO:0048813 199 0.064
blastoderm segmentation GO:0007350 159 0.062
regulation of cellular protein metabolic process GO:0032268 243 0.061
purine nucleotide catabolic process GO:0006195 109 0.061
Human Yeast
regulation of organ morphogenesis GO:2000027 78 0.060
regulation of protein modification process GO:0031399 112 0.059
negative regulation of gene expression epigenetic GO:0045814 77 0.059
Yeast
vesicle mediated transport GO:0016192 381 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.059
Human Yeast
gland development GO:0048732 191 0.059
cell adhesion GO:0007155 136 0.057
amine metabolic process GO:0009308 12 0.057
negative regulation of gene expression GO:0010629 387 0.056
regulation of cell projection organization GO:0031344 92 0.056
wing disc morphogenesis GO:0007472 344 0.055
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.054
peptidyl lysine acetylation GO:0018394 39 0.053
mitotic sister chromatid segregation GO:0000070 87 0.053
Human
negative regulation of cell cycle process GO:0010948 109 0.053
negative regulation of transcription dna templated GO:0045892 237 0.053
regulation of multicellular organismal development GO:2000026 414 0.053
regulation of cellular amine metabolic process GO:0033238 3 0.052
stem cell differentiation GO:0048863 117 0.052
post embryonic appendage morphogenesis GO:0035120 385 0.052
regulation of molecular function GO:0065009 217 0.050
positive regulation of cellular component biogenesis GO:0044089 80 0.049
dendrite development GO:0016358 204 0.048
nuclear division GO:0000280 332 0.048
Human
regulation of apoptotic process GO:0042981 130 0.046
cell death GO:0008219 279 0.046
chromatin remodeling GO:0006338 72 0.045
Human Yeast
modification dependent macromolecule catabolic process GO:0043632 79 0.045
regulation of cell development GO:0060284 215 0.045
somatic muscle development GO:0007525 66 0.044
negative regulation of organelle organization GO:0010639 56 0.044
regulation of gene expression epigenetic GO:0040029 128 0.044
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.043
respiratory system development GO:0060541 213 0.042
peptidyl amino acid modification GO:0018193 105 0.042
limb development GO:0060173 1 0.042
single organism catabolic process GO:0044712 228 0.042
Human Yeast
organic substance transport GO:0071702 257 0.042
positive regulation of cellular protein metabolic process GO:0032270 118 0.041
apoptotic process GO:0006915 159 0.041
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.041
organic substance catabolic process GO:1901575 308 0.041
Human Yeast
morphogenesis of a polarized epithelium GO:0001738 93 0.040
negative regulation of protein complex disassembly GO:0043242 23 0.040
intracellular signal transduction GO:0035556 300 0.040
ubiquitin dependent protein catabolic process GO:0006511 78 0.040
leg disc development GO:0035218 92 0.040
ribonucleoside catabolic process GO:0042454 112 0.039
Human Yeast
negative regulation of signaling GO:0023057 219 0.039
regulation of cellular component biogenesis GO:0044087 201 0.039
chromosome separation GO:0051304 42 0.038
negative regulation of cell differentiation GO:0045596 143 0.038
biological adhesion GO:0022610 138 0.038
negative regulation of signal transduction GO:0009968 206 0.038
cell proliferation GO:0008283 299 0.038
spermatogenesis GO:0007283 200 0.037
regulation of cell cycle phase transition GO:1901987 130 0.037
Human
wnt signaling pathway GO:0016055 98 0.037
regulation of nervous system development GO:0051960 248 0.037
mitotic sister chromatid separation GO:0051306 30 0.036
tube morphogenesis GO:0035239 191 0.035
macromolecule methylation GO:0043414 45 0.035
histolysis GO:0007559 102 0.035
cellular response to dna damage stimulus GO:0006974 223 0.035
Human Yeast
actin cytoskeleton organization GO:0030036 206 0.035
death GO:0016265 284 0.035
negative regulation of biosynthetic process GO:0009890 277 0.034
transcription from rna polymerase ii promoter GO:0006366 368 0.034
Human Yeast
organic acid metabolic process GO:0006082 103 0.034
gland morphogenesis GO:0022612 145 0.033
negative regulation of cell cycle GO:0045786 116 0.033
camera type eye morphogenesis GO:0048593 2 0.033
response to abiotic stimulus GO:0009628 341 0.033
Human
regulation of wnt signaling pathway GO:0030111 68 0.033
macromolecule catabolic process GO:0009057 161 0.033
positive regulation of transcription dna templated GO:0045893 266 0.033
Human Yeast
appendage morphogenesis GO:0035107 397 0.033
negative regulation of cellular response to oxidative stress GO:1900408 1 0.032
neuroblast differentiation GO:0014016 29 0.032
regulation of cell shape GO:0008360 113 0.032
regulation of cell proliferation GO:0042127 163 0.032
establishment of tissue polarity GO:0007164 87 0.032
apoptotic process involved in morphogenesis GO:0060561 3 0.032
exocrine system development GO:0035272 162 0.032
salivary gland histolysis GO:0035070 88 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.031
Human Yeast
organonitrogen compound metabolic process GO:1901564 318 0.031
Human Yeast
axis specification GO:0009798 167 0.031
periodic partitioning GO:0007365 29 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.031
Human Yeast
catabolic process GO:0009056 409 0.031
Human Yeast
imaginal disc derived wing hair organization GO:0035317 45 0.031
anterior posterior axis specification GO:0009948 109 0.030
regulation of catabolic process GO:0009894 170 0.030
spindle organization GO:0007051 253 0.030
Human
glycosyl compound catabolic process GO:1901658 112 0.030
Human Yeast
epithelial cell differentiation GO:0030855 322 0.030
regulation of chromatin organization GO:1902275 32 0.029
macromolecular complex assembly GO:0065003 256 0.029
Human Yeast
intracellular transport GO:0046907 228 0.029
mitotic cell cycle phase transition GO:0044772 138 0.029
Human
regulation of localization GO:0032879 275 0.029
mesenchymal cell development GO:0014031 1 0.029
chromatin modification GO:0016568 147 0.029
Human Yeast
neuron projection guidance GO:0097485 241 0.029
negative regulation of programmed cell death GO:0043069 72 0.028
leg disc morphogenesis GO:0007478 80 0.028
anatomical structure homeostasis GO:0060249 97 0.028
Yeast
organelle assembly GO:0070925 198 0.028
Human
cell recognition GO:0008037 102 0.028
programmed cell death GO:0012501 257 0.028
regulation of neurogenesis GO:0050767 158 0.028
heterocycle catabolic process GO:0046700 166 0.028
Human Yeast
peptidyl lysine modification GO:0018205 57 0.027
establishment or maintenance of cell polarity GO:0007163 167 0.027
regulation of cellular response to stress GO:0080135 89 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
regulation of chromatin modification GO:1903308 28 0.027
tissue death GO:0016271 102 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
Human Yeast
regulation of cellular localization GO:0060341 136 0.026
homeostatic process GO:0042592 199 0.026
Yeast
negative regulation of cell communication GO:0010648 223 0.026
regionalization GO:0003002 416 0.026
morphogenesis of embryonic epithelium GO:0016331 94 0.026
regulation of cell fate commitment GO:0010453 29 0.026
retina development in camera type eye GO:0060041 4 0.025
phagocytosis GO:0006909 215 0.025
regulation of embryonic development GO:0045995 68 0.025
non sensory hair organization GO:0035316 47 0.025
ribonucleotide catabolic process GO:0009261 109 0.025
Human Yeast
regulation of reproductive process GO:2000241 54 0.025
protein localization GO:0008104 284 0.025
negative regulation of mitotic cell cycle GO:0045930 109 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.024
proteasomal protein catabolic process GO:0010498 59 0.024
response to ecdysone GO:0035075 34 0.024
development of primary sexual characteristics GO:0045137 50 0.024
telencephalon development GO:0021537 2 0.024
response to organic cyclic compound GO:0014070 89 0.024
negative regulation of growth GO:0045926 84 0.024
protein alkylation GO:0008213 43 0.024
localization of cell GO:0051674 257 0.024
regulation of epithelial cell differentiation GO:0030856 4 0.023
positive regulation of programmed cell death GO:0043068 62 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.023
establishment of organelle localization GO:0051656 122 0.023
synapse assembly GO:0007416 143 0.022
regulation of gene silencing GO:0060968 63 0.022
secretion by cell GO:0032940 101 0.022
limb morphogenesis GO:0035108 1 0.022
positive regulation of cellular catabolic process GO:0031331 95 0.022
regulation of synaptic transmission GO:0050804 69 0.022
chromatin assembly GO:0031497 48 0.022
Yeast
regulation of neuron projection development GO:0010975 69 0.022
internal peptidyl lysine acetylation GO:0018393 38 0.022
response to oxygen containing compound GO:1901700 200 0.022
gastrulation GO:0007369 70 0.022
regulation of proteolysis GO:0030162 87 0.022
mitotic cell cycle checkpoint GO:0007093 88 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.021
gonad development GO:0008406 50 0.021
cellular protein complex assembly GO:0043623 71 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
Human Yeast
regulation of protein complex assembly GO:0043254 42 0.021
positive regulation of protein modification process GO:0031401 58 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.020
Human Yeast
positive regulation of cell development GO:0010720 61 0.020
cellular protein catabolic process GO:0044257 83 0.020
regulation of transport GO:0051049 181 0.020
tissue morphogenesis GO:0048729 297 0.020
histone methylation GO:0016571 40 0.020
eye photoreceptor cell development GO:0042462 81 0.020
mesenchymal cell differentiation GO:0048762 1 0.020
positive regulation of cell death GO:0010942 69 0.020
nucleotide metabolic process GO:0009117 161 0.020
Human Yeast
camera type eye development GO:0043010 4 0.019
dna methylation GO:0006306 4 0.019
nephron development GO:0072006 3 0.019
response to organic substance GO:0010033 284 0.019
dna metabolic process GO:0006259 227 0.019
Human Yeast
positive regulation of hydrolase activity GO:0051345 78 0.019
forebrain development GO:0030900 2 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.019
cellular catabolic process GO:0044248 372 0.019
Human Yeast
secretion GO:0046903 109 0.019
terminal region determination GO:0007362 25 0.019
dna biosynthetic process GO:0071897 24 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.018
negative regulation of cell development GO:0010721 62 0.018
histone modification GO:0016570 106 0.018
positive regulation of organelle organization GO:0010638 65 0.018
embryonic pattern specification GO:0009880 174 0.018
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
Human Yeast
growth GO:0040007 359 0.018
Human
open tracheal system development GO:0007424 204 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
Human Yeast
regulation of hydrolase activity GO:0051336 97 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
Human Yeast
cell motility GO:0048870 251 0.018
morphogenesis of a branching epithelium GO:0061138 45 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
chromatin silencing GO:0006342 76 0.018
Yeast
male pronucleus assembly GO:0035039 6 0.017
protein complex biogenesis GO:0070271 201 0.017
Human
compound eye retinal cell programmed cell death GO:0046667 23 0.017
positive regulation of cell migration GO:0030335 2 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
Human Yeast
tripartite regional subdivision GO:0007351 103 0.017
autophagic cell death GO:0048102 83 0.017
regulation of cell fate specification GO:0042659 27 0.017
epithelial tube morphogenesis GO:0060562 88 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
sex differentiation GO:0007548 81 0.017
positive regulation of cell proliferation GO:0008284 47 0.016
regulation of nuclear division GO:0051783 58 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
Human Yeast
response to temperature stimulus GO:0009266 106 0.016
nucleoside catabolic process GO:0009164 112 0.016
Human Yeast
regulation of cellular component size GO:0032535 98 0.016
signal release GO:0023061 49 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
Human Yeast
regulation of immune system process GO:0002682 176 0.016
regulation of cell division GO:0051302 72 0.016
dorsal closure GO:0007391 79 0.016
regulation of mitotic sister chromatid separation GO:0010965 28 0.016
response to biotic stimulus GO:0009607 294 0.015
anterior posterior axis specification embryo GO:0008595 103 0.015
branching morphogenesis of an epithelial tube GO:0048754 45 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
regulation of retinal cell programmed cell death GO:0046668 18 0.015
cell cycle checkpoint GO:0000075 95 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
Human Yeast
protein phosphorylation GO:0006468 169 0.015
response to bacterium GO:0009617 198 0.015
regulation of dna metabolic process GO:0051052 34 0.015
Human
embryo development ending in birth or egg hatching GO:0009792 152 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
Human Yeast
eye morphogenesis GO:0048592 260 0.015
cell division GO:0051301 248 0.015
molting cycle GO:0042303 56 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.014
posttranscriptional gene silencing by rna GO:0035194 45 0.014
regulation of neuron differentiation GO:0045664 103 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
Human Yeast
neuromuscular junction development GO:0007528 149 0.014
nitrogen compound transport GO:0071705 85 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
Human Yeast
r3 r4 cell differentiation GO:0048056 12 0.014
dna alkylation GO:0006305 4 0.014
positive regulation of cell communication GO:0010647 250 0.014
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.014
regulation of response to stress GO:0080134 200 0.014
syncytium formation by plasma membrane fusion GO:0000768 43 0.014
detection of stimulus GO:0051606 156 0.014
response to sterol GO:0036314 34 0.014
regulation of protein metabolic process GO:0051246 256 0.014
neuron recognition GO:0008038 101 0.014
nucleotide catabolic process GO:0009166 109 0.013
Human Yeast
imaginal disc derived wing vein specification GO:0007474 48 0.013
rna splicing via transesterification reactions GO:0000375 73 0.013
molting cycle chitin based cuticle GO:0007591 56 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
hair cell differentiation GO:0035315 47 0.013
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.013
muscle organ development GO:0007517 127 0.013
eye photoreceptor cell fate commitment GO:0042706 37 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
positive regulation of epithelial cell differentiation GO:0030858 1 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
compound eye photoreceptor development GO:0042051 78 0.013
rna localization GO:0006403 115 0.013
purine containing compound catabolic process GO:0072523 112 0.013
Human Yeast
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
photoreceptor cell development GO:0042461 96 0.013
cellular macromolecule localization GO:0070727 220 0.013
cell fate determination GO:0001709 91 0.013
regulation of tube size open tracheal system GO:0035151 43 0.012
morphogenesis of follicular epithelium GO:0016333 36 0.012
regulation of stem cell proliferation GO:0072091 40 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
Human Yeast
chitin based cuticle development GO:0040003 49 0.012
developmental maturation GO:0021700 172 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
cellular component disassembly GO:0022411 46 0.012
posttranscriptional gene silencing GO:0016441 46 0.012
regulation of catalytic activity GO:0050790 185 0.012
organelle localization GO:0051640 148 0.012
negative regulation of cytoskeleton organization GO:0051494 30 0.012
positive regulation of catabolic process GO:0009896 105 0.012
actin filament based process GO:0030029 220 0.012
negative regulation of developmental process GO:0051093 201 0.012
response to alcohol GO:0097305 95 0.012
positive regulation of protein complex assembly GO:0031334 22 0.011
microtubule polymerization or depolymerization GO:0031109 39 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
Human Yeast
axon development GO:0061564 297 0.011
telomere organization GO:0032200 21 0.011
Yeast
organonitrogen compound catabolic process GO:1901565 128 0.011
Human Yeast
embryonic axis specification GO:0000578 107 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
regulation of mitotic sister chromatid segregation GO:0033047 28 0.011
digestive tract morphogenesis GO:0048546 127 0.010
positive regulation of biosynthetic process GO:0009891 316 0.010
Human Yeast
positive regulation of response to stimulus GO:0048584 323 0.010
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.010
metaphase anaphase transition of cell cycle GO:0044784 28 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
central nervous system projection neuron axonogenesis GO:0021952 6 0.010
dna methylation or demethylation GO:0044728 4 0.010
induction of programmed cell death by hormones GO:0035081 12 0.010
central nervous system development GO:0007417 201 0.010
meiotic nuclear division GO:0007126 151 0.010
organophosphate metabolic process GO:0019637 195 0.010
Human Yeast
morphogenesis of a branching structure GO:0001763 45 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
Human Yeast

Ino80 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029