Drosophila melanogaster

4 known processes

Trap1 (Dmel_CG3152)

CG3152 gene product from transcript CG3152-RA

(Aliases: CG3152,trap1,TRAP1,TRAP1dr,dtrap-1,Dmel\CG3152)

Trap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to oxidative stress GO:0006979 86 0.272
response to heat GO:0009408 63 0.245
cellular response to heat GO:0034605 24 0.243
response to abiotic stimulus GO:0009628 341 0.197
organonitrogen compound metabolic process GO:1901564 318 0.183
response to temperature stimulus GO:0009266 106 0.140
catabolic process GO:0009056 409 0.125
positive regulation of macromolecule metabolic process GO:0010604 405 0.123
cellular macromolecule catabolic process GO:0044265 136 0.120
regulation of intracellular signal transduction GO:1902531 236 0.109
Rat
cellular catabolic process GO:0044248 372 0.107
intracellular signal transduction GO:0035556 300 0.107
Rat
positive regulation of gene expression GO:0010628 290 0.103
atp metabolic process GO:0046034 49 0.102
purine nucleoside metabolic process GO:0042278 127 0.100
purine nucleotide catabolic process GO:0006195 109 0.100
response to organic substance GO:0010033 284 0.098
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.096
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.095
regulation of immune system process GO:0002682 176 0.094
purine containing compound catabolic process GO:0072523 112 0.091
cellular nitrogen compound catabolic process GO:0044270 165 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.089
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.088
positive regulation of biosynthetic process GO:0009891 316 0.087
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.087
organophosphate metabolic process GO:0019637 195 0.085
negative regulation of cellular metabolic process GO:0031324 382 0.085
Human
immune response GO:0006955 246 0.081
response to oxygen containing compound GO:1901700 200 0.080
regulation of response to stress GO:0080134 200 0.079
Rat
nucleobase containing compound catabolic process GO:0034655 165 0.078
purine containing compound metabolic process GO:0072521 155 0.075
regulation of molecular function GO:0065009 217 0.075
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.074
nucleotide catabolic process GO:0009166 109 0.074
nucleoside phosphate metabolic process GO:0006753 162 0.073
single organism catabolic process GO:0044712 228 0.073
aromatic compound catabolic process GO:0019439 166 0.072
positive regulation of rna metabolic process GO:0051254 271 0.070
glycosyl compound catabolic process GO:1901658 112 0.070
nucleotide metabolic process GO:0009117 161 0.070
heterocycle catabolic process GO:0046700 166 0.066
small molecule metabolic process GO:0044281 305 0.066
ribonucleoside metabolic process GO:0009119 127 0.065
aging GO:0007568 143 0.064
ribonucleoside triphosphate metabolic process GO:0009199 119 0.062
protein localization GO:0008104 284 0.060
posttranscriptional regulation of gene expression GO:0010608 145 0.059
cellular protein modification process GO:0006464 438 0.058
purine nucleotide metabolic process GO:0006163 146 0.057
regulation of multicellular organismal development GO:2000026 414 0.057
homeostatic process GO:0042592 199 0.056
nucleobase containing small molecule metabolic process GO:0055086 174 0.056
regulation of defense response GO:0031347 102 0.055
organic substance transport GO:0071702 257 0.055
purine ribonucleoside metabolic process GO:0046128 127 0.055
regulation of immune response GO:0050776 118 0.055
positive regulation of transcription dna templated GO:0045893 266 0.054
glycosyl compound metabolic process GO:1901657 127 0.053
organic substance catabolic process GO:1901575 308 0.053
nucleoside phosphate catabolic process GO:1901292 110 0.052
regulation of protein metabolic process GO:0051246 256 0.052
positive regulation of nucleic acid templated transcription GO:1903508 266 0.051
purine nucleoside catabolic process GO:0006152 112 0.051
apoptotic process GO:0006915 159 0.051
Rat
cellular response to reactive oxygen species GO:0034614 14 0.050
nucleoside triphosphate metabolic process GO:0009141 120 0.050
purine ribonucleotide metabolic process GO:0009150 145 0.050
regulation of catalytic activity GO:0050790 185 0.050
ribose phosphate metabolic process GO:0019693 145 0.050
ribonucleotide metabolic process GO:0009259 145 0.049
purine nucleoside triphosphate metabolic process GO:0009144 119 0.049
single organism biosynthetic process GO:0044711 206 0.048
positive regulation of multicellular organismal process GO:0051240 143 0.048
regulation of cellular protein metabolic process GO:0032268 243 0.047
carbohydrate derivative catabolic process GO:1901136 118 0.047
locomotory behavior GO:0007626 176 0.046
positive regulation of cellular biosynthetic process GO:0031328 316 0.046
organonitrogen compound catabolic process GO:1901565 128 0.046
purine nucleoside monophosphate metabolic process GO:0009126 50 0.045
ribonucleotide catabolic process GO:0009261 109 0.044
nucleoside catabolic process GO:0009164 112 0.043
negative regulation of response to stimulus GO:0048585 258 0.042
Rat
purine nucleoside triphosphate catabolic process GO:0009146 108 0.041
defense response GO:0006952 300 0.041
response to oxygen radical GO:0000305 3 0.041
cellular response to oxidative stress GO:0034599 28 0.040
Rat
ribonucleoside monophosphate metabolic process GO:0009161 51 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.039
purine ribonucleoside catabolic process GO:0046130 112 0.039
negative regulation of cell communication GO:0010648 223 0.039
Rat
nucleoside metabolic process GO:0009116 127 0.038
response to bacterium GO:0009617 198 0.038
response to biotic stimulus GO:0009607 294 0.038
organic acid metabolic process GO:0006082 103 0.038
phosphorylation GO:0016310 294 0.037
positive regulation of response to stimulus GO:0048584 323 0.037
death GO:0016265 284 0.037
Rat
transcription from rna polymerase ii promoter GO:0006366 368 0.037
response to nitrogen compound GO:1901698 90 0.037
negative regulation of gene expression GO:0010629 387 0.037
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.036
oxidation reduction process GO:0055114 123 0.036
Human
response to extracellular stimulus GO:0009991 116 0.036
immune system process GO:0002376 347 0.036
ribonucleoside triphosphate catabolic process GO:0009203 108 0.035
regulation of cellular component biogenesis GO:0044087 201 0.035
defense response to other organism GO:0098542 225 0.035
intracellular protein transport GO:0006886 104 0.035
regulation of multi organism process GO:0043900 131 0.034
localization of cell GO:0051674 257 0.034
establishment of protein localization to organelle GO:0072594 62 0.034
determination of adult lifespan GO:0008340 137 0.034
ribonucleoside catabolic process GO:0042454 112 0.034
single organism cellular localization GO:1902580 180 0.033
cellular macromolecule localization GO:0070727 220 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
Rat
protein modification process GO:0036211 438 0.032
programmed cell death GO:0012501 257 0.032
Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.032
establishment of localization in cell GO:0051649 402 0.031
regulation of innate immune response GO:0045088 71 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.031
macromolecule catabolic process GO:0009057 161 0.031
oxoacid metabolic process GO:0043436 103 0.031
chromosome organization GO:0051276 360 0.031
response to other organism GO:0051707 293 0.031
nucleoside triphosphate catabolic process GO:0009143 108 0.030
positive regulation of apoptotic signaling pathway GO:2001235 4 0.030
positive regulation of molecular function GO:0044093 136 0.030
negative regulation of signal transduction GO:0009968 206 0.030
Rat
organophosphate catabolic process GO:0046434 112 0.030
defense response to bacterium GO:0042742 178 0.030
protein modification by small protein conjugation or removal GO:0070647 106 0.030
cytoplasmic transport GO:0016482 130 0.030
regulation of catabolic process GO:0009894 170 0.029
regulation of cell differentiation GO:0045595 302 0.029
regulation of dna metabolic process GO:0051052 34 0.028
cellular respiration GO:0045333 26 0.028
Human
intracellular transport GO:0046907 228 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.028
cell death GO:0008219 279 0.028
Rat
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.027
growth GO:0040007 359 0.027
regulation of cell cycle GO:0051726 291 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.026
protein transport GO:0015031 155 0.026
regulation of cellular response to oxidative stress GO:1900407 4 0.025
Rat
regulation of phosphate metabolic process GO:0019220 210 0.025
developmental growth GO:0048589 280 0.025
negative regulation of biosynthetic process GO:0009890 277 0.025
positive regulation of signaling GO:0023056 243 0.025
macromolecular complex assembly GO:0065003 256 0.025
response to organophosphorus GO:0046683 2 0.025
response to endogenous stimulus GO:0009719 119 0.025
regulation of growth GO:0040008 233 0.024
proteolysis GO:0006508 192 0.024
adult behavior GO:0030534 137 0.024
positive regulation of signal transduction GO:0009967 223 0.024
establishment of protein localization GO:0045184 163 0.024
regulation of transferase activity GO:0051338 58 0.024
response to reactive oxygen species GO:0000302 24 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
negative regulation of molecular function GO:0044092 51 0.023
negative regulation of protein metabolic process GO:0051248 85 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.023
nuclear division GO:0000280 332 0.023
regulation of apoptotic process GO:0042981 130 0.023
Rat
phagocytosis GO:0006909 215 0.023
response to superoxide GO:0000303 3 0.023
dna metabolic process GO:0006259 227 0.023
regulation of response to oxidative stress GO:1902882 4 0.023
Rat
positive regulation of cellular component organization GO:0051130 156 0.023
immune response regulating signaling pathway GO:0002764 2 0.023
cellular lipid metabolic process GO:0044255 83 0.023
innate immune response GO:0045087 144 0.022
energy derivation by oxidation of organic compounds GO:0015980 32 0.022
Human
cellular protein localization GO:0034613 160 0.022
ribonucleoside monophosphate catabolic process GO:0009158 39 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.022
response to hydrogen peroxide GO:0042542 11 0.022
cellular response to organic substance GO:0071310 132 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
regulation of hydrolase activity GO:0051336 97 0.021
transmembrane transport GO:0055085 139 0.021
negative regulation of catalytic activity GO:0043086 42 0.021
multicellular organismal aging GO:0010259 140 0.021
regulation of protein modification process GO:0031399 112 0.021
adult locomotory behavior GO:0008344 76 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
response to starvation GO:0042594 97 0.021
organelle fission GO:0048285 340 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
protein modification by small protein conjugation GO:0032446 79 0.020
vesicle mediated transport GO:0016192 381 0.020
cell maturation GO:0048469 144 0.020
protein maturation GO:0051604 71 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
lipid metabolic process GO:0006629 121 0.020
positive regulation of defense response GO:0031349 59 0.020
positive regulation of cellular catabolic process GO:0031331 95 0.020
nucleoside monophosphate metabolic process GO:0009123 52 0.020
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.020
positive regulation of immune response GO:0050778 63 0.020
positive regulation of protein metabolic process GO:0051247 128 0.020
purine ribonucleotide catabolic process GO:0009154 109 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.019
regulation of cell cycle process GO:0010564 181 0.019
negative regulation of immune system process GO:0002683 50 0.019
negative regulation of developmental process GO:0051093 201 0.019
developmental maturation GO:0021700 172 0.019
immune response activating signal transduction GO:0002757 2 0.019
positive regulation of hydrolase activity GO:0051345 78 0.019
generation of precursor metabolites and energy GO:0006091 42 0.019
Human
cell division GO:0051301 248 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
protein catabolic process GO:0030163 101 0.018
protein targeting GO:0006605 64 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.018
chromatin modification GO:0016568 147 0.018
mitochondrion organization GO:0007005 65 0.018
protein phosphorylation GO:0006468 169 0.018
neurological system process GO:0050877 358 0.018
negative regulation of phosphorus metabolic process GO:0010563 45 0.018
regulation of cell death GO:0010941 173 0.018
Rat
positive regulation of cell communication GO:0010647 250 0.018
ion transport GO:0006811 145 0.018
negative regulation of cell death GO:0060548 81 0.017
Rat
anion homeostasis GO:0055081 3 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
cell migration GO:0016477 238 0.017
negative regulation of cellular response to oxidative stress GO:1900408 1 0.017
Rat
inositol lipid mediated signaling GO:0048017 4 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
rna processing GO:0006396 147 0.017
spermatogenesis GO:0007283 200 0.017
negative regulation of signaling GO:0023057 219 0.017
Rat
response to external biotic stimulus GO:0043207 293 0.017
protein ubiquitination GO:0016567 70 0.017
metal ion homeostasis GO:0055065 44 0.016
adult chitin containing cuticle pigmentation GO:0048085 16 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.016
regulation of cell development GO:0060284 215 0.016
cell proliferation GO:0008283 299 0.016
regulation of phosphorylation GO:0042325 147 0.016
response to copper ion GO:0046688 4 0.016
regulation of programmed cell death GO:0043067 152 0.016
Rat
response to lipopolysaccharide GO:0032496 4 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
regulation of cellular catabolic process GO:0031329 157 0.015
regulation of nucleotide catabolic process GO:0030811 48 0.015
purine nucleoside monophosphate catabolic process GO:0009128 38 0.015
organophosphate biosynthetic process GO:0090407 46 0.015
positive regulation of immune system process GO:0002684 68 0.015
single organism behavior GO:0044708 391 0.015
epithelial cell differentiation GO:0030855 322 0.015
endocytosis GO:0006897 310 0.015
protein localization to organelle GO:0033365 82 0.015
forebrain development GO:0030900 2 0.015
gtp metabolic process GO:0046039 72 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
Rat
cellular response to dna damage stimulus GO:0006974 223 0.015
regulation of organelle organization GO:0033043 196 0.015
translation GO:0006412 69 0.015
regulation of anatomical structure size GO:0090066 163 0.015
cuticle development GO:0042335 86 0.015
appendage development GO:0048736 401 0.015
appendage morphogenesis GO:0035107 397 0.015
dendrite development GO:0016358 204 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
regulation of bmp signaling pathway GO:0030510 23 0.014
cation transport GO:0006812 110 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
ras protein signal transduction GO:0007265 88 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.014
mapk cascade GO:0000165 107 0.014
cellular protein catabolic process GO:0044257 83 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
molting cycle process GO:0022404 29 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
regulation of cellular response to stress GO:0080135 89 0.014
Rat
body morphogenesis GO:0010171 2 0.014
regulation of transport GO:0051049 181 0.014
nucleoside monophosphate catabolic process GO:0009125 39 0.014
kidney development GO:0001822 3 0.014
heart development GO:0007507 82 0.013
mitochondrial transport GO:0006839 8 0.013
vitamin biosynthetic process GO:0009110 1 0.013
metal ion transport GO:0030001 74 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
regionalization GO:0003002 416 0.013
intrinsic apoptotic signaling pathway GO:0097193 16 0.013
Rat
response to inorganic substance GO:0010035 44 0.013
intracellular protein transmembrane transport GO:0065002 4 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
cellular amine metabolic process GO:0044106 12 0.013
intracellular protein transmembrane import GO:0044743 4 0.013
amine metabolic process GO:0009308 12 0.013
regulation of developmental growth GO:0048638 174 0.013
protein targeting to nucleus GO:0044744 51 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
phosphatidylinositol mediated signaling GO:0048015 4 0.013
response to hypoxia GO:0001666 53 0.013
negative regulation of phosphate metabolic process GO:0045936 45 0.013
rna catabolic process GO:0006401 37 0.013
innate immune response activating signal transduction GO:0002758 2 0.013
sensory organ morphogenesis GO:0090596 260 0.013
hydrogen peroxide catabolic process GO:0042744 6 0.013
regulation of mapk cascade GO:0043408 92 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.012
regulation of protein kinase activity GO:0045859 51 0.012
protein transmembrane transport GO:0071806 4 0.012
atp synthesis coupled electron transport GO:0042773 8 0.012
chemical homeostasis GO:0048878 92 0.012
cell motility GO:0048870 251 0.012
cellular homeostasis GO:0019725 80 0.012
response to organonitrogen compound GO:0010243 75 0.012
positive regulation of endopeptidase activity GO:0010950 26 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
axis specification GO:0009798 167 0.012
regulation of developmental pigmentation GO:0048070 24 0.012
gene silencing GO:0016458 138 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
response to alcohol GO:0097305 95 0.012
xenobiotic catabolic process GO:0042178 1 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
regulation of proteolysis GO:0030162 87 0.012
oxidoreduction coenzyme metabolic process GO:0006733 2 0.012
atp catabolic process GO:0006200 38 0.012
reactive oxygen species metabolic process GO:0072593 22 0.012
cell aging GO:0007569 2 0.011
ion homeostasis GO:0050801 55 0.011
regulation of nucleoside metabolic process GO:0009118 50 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
single organism intracellular transport GO:1902582 207 0.011
response to radiation GO:0009314 155 0.011
oxidative phosphorylation GO:0006119 9 0.011
meiotic nuclear division GO:0007126 151 0.011
meiotic cell cycle process GO:1903046 132 0.011
chromatin organization GO:0006325 207 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
trna processing GO:0008033 3 0.011
circulatory system development GO:0072359 82 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
signal release GO:0023061 49 0.011
mitotic spindle organization GO:0007052 220 0.011
pyridine containing compound metabolic process GO:0072524 3 0.011
protein processing GO:0016485 68 0.011
regulation of neurogenesis GO:0050767 158 0.011
compound eye morphogenesis GO:0001745 249 0.011
positive regulation of cell motility GO:2000147 3 0.011
protein complex assembly GO:0006461 200 0.011
electron transport chain GO:0022900 14 0.011
blastoderm segmentation GO:0007350 159 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
response to decreased oxygen levels GO:0036293 58 0.010
ameboidal type cell migration GO:0001667 151 0.010
negative regulation of kinase activity GO:0033673 16 0.010
positive regulation of protein modification process GO:0031401 58 0.010
response to ethanol GO:0045471 59 0.010
response to nutrient levels GO:0031667 114 0.010
pyridine nucleotide metabolic process GO:0019362 2 0.010
regulation of peptidase activity GO:0052547 39 0.010
peptidyl amino acid modification GO:0018193 105 0.010
rna splicing GO:0008380 83 0.010
polyol biosynthetic process GO:0046173 3 0.010
pole plasm mrna localization GO:0019094 49 0.010
negative regulation of intracellular signal transduction GO:1902532 57 0.010
Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.010
mitotic nuclear division GO:0007067 213 0.010

Trap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.144
nervous system disease DOID:863 0 0.034
disease of metabolism DOID:0014667 0 0.023
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.017
cardiovascular system disease DOID:1287 0 0.013
acquired metabolic disease DOID:0060158 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.012
glucose metabolism disease DOID:4194 0 0.012
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
synucleinopathy DOID:0050890 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011