Drosophila melanogaster

132 known processes

twf (Dmel_CG3172)

twinfilin

(Aliases: Dmel\CG3172,CG3172,Twf,A6)

twf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mushroom body development GO:0016319 70 0.928
regulation of actin filament length GO:0030832 27 0.826
vesicle mediated transport GO:0016192 381 0.794
regulation of actin polymerization or depolymerization GO:0008064 27 0.777
epithelial cell migration GO:0010631 148 0.687
regulation of actin filament polymerization GO:0030833 25 0.633
regulation of cellular component size GO:0032535 98 0.595
ameboidal type cell migration GO:0001667 151 0.504
cell proliferation GO:0008283 299 0.488
actin polymerization or depolymerization GO:0008154 31 0.427
small molecule metabolic process GO:0044281 305 0.390
actin cytoskeleton organization GO:0030036 206 0.381
endocytosis GO:0006897 310 0.371
epithelium migration GO:0090132 148 0.340
regulation of anatomical structure size GO:0090066 163 0.334
actin filament polymerization GO:0030041 27 0.301
regulation of protein polymerization GO:0032271 28 0.300
cellular macromolecule localization GO:0070727 220 0.291
actin filament organization GO:0007015 126 0.290
regulation of actin cytoskeleton organization GO:0032956 42 0.280
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.246
actin filament based process GO:0030029 220 0.243
regulation of cytoskeleton organization GO:0051493 89 0.225
neuromuscular junction development GO:0007528 149 0.220
nucleoside phosphate metabolic process GO:0006753 162 0.187
protein complex assembly GO:0006461 200 0.186
positive regulation of cellular component organization GO:0051130 156 0.179
organophosphate metabolic process GO:0019637 195 0.172
epithelial cell differentiation GO:0030855 322 0.168
glycosyl compound metabolic process GO:1901657 127 0.166
ovarian follicle cell migration GO:0007297 121 0.165
positive regulation of protein polymerization GO:0032273 14 0.157
tissue migration GO:0090130 155 0.157
columnar cuboidal epithelial cell development GO:0002066 249 0.153
nucleoside phosphate catabolic process GO:1901292 110 0.142
nucleobase containing small molecule metabolic process GO:0055086 174 0.140
camera type eye development GO:0043010 4 0.138
protein localization GO:0008104 284 0.138
Yeast Mouse
border follicle cell migration GO:0007298 113 0.137
synaptic growth at neuromuscular junction GO:0051124 119 0.136
cell migration GO:0016477 238 0.134
organelle fission GO:0048285 340 0.132
developmental growth GO:0048589 280 0.131
cellular macromolecular complex assembly GO:0034622 153 0.131
regulation of endocytosis GO:0030100 37 0.131
ribonucleoside catabolic process GO:0042454 112 0.130
growth GO:0040007 359 0.130
organonitrogen compound metabolic process GO:1901564 318 0.128
regulation of protein complex assembly GO:0043254 42 0.127
epithelial cell development GO:0002064 274 0.127
head development GO:0060322 135 0.119
negative regulation of signaling GO:0023057 219 0.114
cell motility GO:0048870 251 0.114
cytokinesis GO:0000910 90 0.110
single organism cellular localization GO:1902580 180 0.109
positive regulation of actin filament polymerization GO:0030838 11 0.109
positive regulation of cell projection organization GO:0031346 29 0.107
positive regulation of cellular component biogenesis GO:0044089 80 0.105
establishment of localization in cell GO:0051649 402 0.105
dendrite development GO:0016358 204 0.104
ovarian follicle cell development GO:0030707 248 0.104
ribonucleoside triphosphate catabolic process GO:0009203 108 0.103
cellular response to chemical stimulus GO:0070887 199 0.103
single organism catabolic process GO:0044712 228 0.102
purine nucleoside triphosphate metabolic process GO:0009144 119 0.101
nucleoside catabolic process GO:0009164 112 0.101
morphogenesis of an epithelium GO:0002009 276 0.097
regulation of lamellipodium assembly GO:0010591 15 0.097
appendage development GO:0048736 401 0.096
protein complex biogenesis GO:0070271 201 0.091
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.091
regulation of cell projection organization GO:0031344 92 0.091
regulation of anatomical structure morphogenesis GO:0022603 242 0.086
male gamete generation GO:0048232 201 0.085
regulation of notch signaling pathway GO:0008593 100 0.085
meiotic cell cycle process GO:1903046 132 0.085
purine ribonucleotide metabolic process GO:0009150 145 0.085
ribonucleoside metabolic process GO:0009119 127 0.084
phosphorylation GO:0016310 294 0.083
Human Mouse
appendage morphogenesis GO:0035107 397 0.083
regulation of cell cycle process GO:0010564 181 0.083
actin nucleation GO:0045010 8 0.082
glycosyl compound catabolic process GO:1901658 112 0.080
carbohydrate derivative metabolic process GO:1901135 217 0.080
regulation of vesicle mediated transport GO:0060627 59 0.079
regulation of organelle organization GO:0033043 196 0.079
nucleoside metabolic process GO:0009116 127 0.079
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.079
regulation of phosphorus metabolic process GO:0051174 210 0.078
Human
regulation of cellular component biogenesis GO:0044087 201 0.078
positive regulation of cellular amine metabolic process GO:0033240 0 0.076
regulation of actin filament based process GO:0032970 42 0.075
phagocytosis GO:0006909 215 0.074
ribose phosphate metabolic process GO:0019693 145 0.071
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.071
regulation of lamellipodium organization GO:1902743 15 0.069
purine nucleotide metabolic process GO:0006163 146 0.068
axon guidance GO:0007411 233 0.067
meiotic cytokinesis GO:0033206 33 0.067
positive regulation of signal transduction GO:0009967 223 0.067
cellular amine metabolic process GO:0044106 12 0.067
regulation of developmental growth GO:0048638 174 0.066
cellular protein localization GO:0034613 160 0.066
positive regulation of signaling GO:0023056 243 0.066
nucleoside triphosphate metabolic process GO:0009141 120 0.065
protein depolymerization GO:0051261 31 0.065
carboxylic acid metabolic process GO:0019752 92 0.065
positive regulation of cell communication GO:0010647 250 0.065
imaginal disc derived appendage morphogenesis GO:0035114 395 0.064
cellular lipid metabolic process GO:0044255 83 0.064
purine ribonucleoside metabolic process GO:0046128 127 0.064
ribonucleoside triphosphate metabolic process GO:0009199 119 0.063
macromolecular complex assembly GO:0065003 256 0.063
purine containing compound metabolic process GO:0072521 155 0.062
post embryonic appendage morphogenesis GO:0035120 385 0.062
synapse organization GO:0050808 196 0.061
nucleotide metabolic process GO:0009117 161 0.060
purine nucleotide catabolic process GO:0006195 109 0.059
purine nucleoside catabolic process GO:0006152 112 0.059
cell projection assembly GO:0030031 94 0.059
purine nucleoside metabolic process GO:0042278 127 0.059
intracellular signal transduction GO:0035556 300 0.058
nuclear division GO:0000280 332 0.058
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.057
organic substance catabolic process GO:1901575 308 0.056
organonitrogen compound catabolic process GO:1901565 128 0.056
organic substance transport GO:0071702 257 0.056
spermatogenesis GO:0007283 200 0.054
secretion by cell GO:0032940 101 0.054
protein transport GO:0015031 155 0.053
proteolysis GO:0006508 192 0.053
protein modification process GO:0036211 438 0.052
Human Mouse
regulation of growth GO:0040008 233 0.051
organelle localization GO:0051640 148 0.051
single organism intracellular transport GO:1902582 207 0.049
regulation of cellular ketone metabolic process GO:0010565 3 0.048
regulation of actin filament depolymerization GO:0030834 3 0.048
Mouse
ribonucleotide metabolic process GO:0009259 145 0.047
purine nucleoside triphosphate catabolic process GO:0009146 108 0.046
cellular catabolic process GO:0044248 372 0.045
positive regulation of phosphorus metabolic process GO:0010562 139 0.045
lamellipodium assembly GO:0030032 21 0.045
cellular protein complex disassembly GO:0043624 35 0.045
purine ribonucleotide catabolic process GO:0009154 109 0.045
adult locomotory behavior GO:0008344 76 0.044
positive regulation of response to stimulus GO:0048584 323 0.044
positive regulation of cytoskeleton organization GO:0051495 21 0.043
regulation of phosphate metabolic process GO:0019220 210 0.042
Human
locomotory behavior GO:0007626 176 0.042
endomembrane system organization GO:0010256 119 0.042
imaginal disc derived appendage development GO:0048737 399 0.042
regulation of programmed cell death GO:0043067 152 0.041
cellular component assembly involved in morphogenesis GO:0010927 151 0.040
response to organic substance GO:0010033 284 0.040
organelle assembly GO:0070925 198 0.040
positive regulation of nucleotide metabolic process GO:0045981 55 0.039
cell death GO:0008219 279 0.039
response to alcohol GO:0097305 95 0.038
negative regulation of cellular catabolic process GO:0031330 34 0.038
chemotaxis GO:0006935 249 0.038
positive regulation of phosphate metabolic process GO:0045937 139 0.037
response to endogenous stimulus GO:0009719 119 0.037
protein phosphorylation GO:0006468 169 0.037
Human Mouse
cellular ketone metabolic process GO:0042180 24 0.037
positive regulation of notch signaling pathway GO:0045747 34 0.036
single organism behavior GO:0044708 391 0.036
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.035
regionalization GO:0003002 416 0.035
ribonucleotide catabolic process GO:0009261 109 0.034
cortical actin cytoskeleton organization GO:0030866 24 0.034
death GO:0016265 284 0.034
nucleoside triphosphate catabolic process GO:0009143 108 0.034
wing disc morphogenesis GO:0007472 344 0.034
cellular response to organic substance GO:0071310 132 0.034
positive regulation of lipid metabolic process GO:0045834 4 0.033
regulation of phosphorylation GO:0042325 147 0.033
Human
protein polymerization GO:0051258 42 0.033
regulation of cellular amine metabolic process GO:0033238 3 0.033
taxis GO:0042330 304 0.032
positive regulation of response to external stimulus GO:0032103 44 0.032
purine ribonucleoside catabolic process GO:0046130 112 0.031
purine containing compound catabolic process GO:0072523 112 0.030
programmed cell death GO:0012501 257 0.030
single organism carbohydrate metabolic process GO:0044723 72 0.030
carbohydrate derivative catabolic process GO:1901136 118 0.030
membrane budding GO:0006900 4 0.030
tissue morphogenesis GO:0048729 297 0.030
establishment of proximal distal cell polarity GO:0022606 4 0.030
intracellular transport GO:0046907 228 0.029
regulation of cell shape GO:0008360 113 0.029
establishment of nucleus localization GO:0040023 26 0.029
guanosine containing compound catabolic process GO:1901069 74 0.028
homeostatic process GO:0042592 199 0.028
regulation of cell morphogenesis GO:0022604 163 0.028
membrane organization GO:0061024 112 0.027
negative regulation of signal transduction GO:0009968 206 0.027
single fertilization GO:0007338 24 0.027
positive regulation of protein complex assembly GO:0031334 22 0.027
cytoskeleton dependent cytokinesis GO:0061640 81 0.027
atp metabolic process GO:0046034 49 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.026
regulation of apoptotic process GO:0042981 130 0.026
enzyme linked receptor protein signaling pathway GO:0007167 179 0.026
organic acid metabolic process GO:0006082 103 0.026
regulation of cell development GO:0060284 215 0.026
nucleotide catabolic process GO:0009166 109 0.026
endosomal transport GO:0016197 44 0.026
mapk cascade GO:0000165 107 0.026
regulation of synapse organization GO:0050807 110 0.025
central nervous system development GO:0007417 201 0.025
cytoplasmic transport GO:0016482 130 0.025
apoptotic process GO:0006915 159 0.024
biological adhesion GO:0022610 138 0.024
cell adhesion GO:0007155 136 0.024
cellular protein modification process GO:0006464 438 0.024
Human Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.023
sphingolipid metabolic process GO:0006665 19 0.023
regulation of filopodium assembly GO:0051489 24 0.023
localization of cell GO:0051674 257 0.023
golgi organization GO:0007030 66 0.023
reproductive structure development GO:0048608 74 0.022
cellular amino acid metabolic process GO:0006520 61 0.022
positive regulation of organelle organization GO:0010638 65 0.021
intracellular protein transport GO:0006886 104 0.021
cellular protein complex assembly GO:0043623 71 0.021
negative regulation of proteolysis GO:0045861 31 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
guanosine containing compound metabolic process GO:1901068 74 0.020
positive regulation of gtpase activity GO:0043547 43 0.020
maintenance of protein location in cell GO:0032507 26 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
regulation of proteolysis GO:0030162 87 0.019
body morphogenesis GO:0010171 2 0.019
negative regulation of cell communication GO:0010648 223 0.019
negative regulation of gene expression GO:0010629 387 0.019
negative regulation of apoptotic process GO:0043066 63 0.019
establishment of protein localization GO:0045184 163 0.019
small gtpase mediated signal transduction GO:0007264 88 0.019
positive regulation of cell motility GO:2000147 3 0.019
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.018
amine metabolic process GO:0009308 12 0.018
regulation of cell death GO:0010941 173 0.018
lamellipodium organization GO:0097581 21 0.018
female meiotic division GO:0007143 70 0.018
instar larval development GO:0002168 55 0.018
stem cell proliferation GO:0072089 88 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
cell recognition GO:0008037 102 0.017
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.017
positive regulation of lamellipodium organization GO:1902745 7 0.017
regulation of stress activated mapk cascade GO:0032872 41 0.017
ribonucleoside monophosphate catabolic process GO:0009158 39 0.017
regulation of hydrolase activity GO:0051336 97 0.017
establishment of organelle localization GO:0051656 122 0.017
negative regulation of cytoskeleton organization GO:0051494 30 0.017
Yeast Mouse
neuron projection extension GO:1990138 32 0.017
regulation of cell projection assembly GO:0060491 30 0.017
negative regulation of cell cycle GO:0045786 116 0.016
regulation of cell substrate adhesion GO:0010810 2 0.016
establishment of monopolar cell polarity GO:0061162 15 0.016
cilium assembly GO:0042384 38 0.016
arp2 3 complex mediated actin nucleation GO:0034314 3 0.016
cation transport GO:0006812 110 0.016
mitotic nuclear division GO:0007067 213 0.016
regulation of phosphatase activity GO:0010921 3 0.016
chromosome organization GO:0051276 360 0.016
response to oxygen containing compound GO:1901700 200 0.015
regulation of nervous system development GO:0051960 248 0.015
positive regulation of cell proliferation GO:0008284 47 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
positive regulation of protein secretion GO:0050714 9 0.015
meiotic cell cycle GO:0051321 171 0.015
synapse assembly GO:0007416 143 0.015
cellular component disassembly GO:0022411 46 0.015
retrograde transport endosome to golgi GO:0042147 3 0.015
carbohydrate metabolic process GO:0005975 82 0.015
neural precursor cell proliferation GO:0061351 75 0.014
secretion GO:0046903 109 0.014
cellular response to oxygen containing compound GO:1901701 79 0.014
regulation of cell cycle GO:0051726 291 0.014
response to abiotic stimulus GO:0009628 341 0.014
positive regulation of nucleotide catabolic process GO:0030813 46 0.014
regulation of protein processing GO:0070613 32 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
regulation of molecular function GO:0065009 217 0.014
aromatic compound catabolic process GO:0019439 166 0.014
regulation of protein depolymerization GO:1901879 27 0.014
Mouse
imaginal disc derived wing hair site selection GO:0035320 4 0.014
spermatid differentiation GO:0048515 114 0.014
regulation of catalytic activity GO:0050790 185 0.014
ceramide metabolic process GO:0006672 7 0.013
establishment of mitochondrion localization GO:0051654 7 0.013
larval development GO:0002164 104 0.013
catabolic process GO:0009056 409 0.013
anatomical structure homeostasis GO:0060249 97 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
exocytosis GO:0006887 28 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
sex differentiation GO:0007548 81 0.013
peptidyl tyrosine modification GO:0018212 24 0.012
Mouse
cell division GO:0051301 248 0.012
glycoprotein biosynthetic process GO:0009101 41 0.012
actin filament bundle assembly GO:0051017 26 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
spermatid development GO:0007286 98 0.012
lipid biosynthetic process GO:0008610 46 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
notch signaling pathway GO:0007219 120 0.012
regulation of cell division GO:0051302 72 0.012
cytoplasmic microtubule organization GO:0031122 22 0.012
protein kinase b signaling GO:0043491 1 0.012
membrane depolarization GO:0051899 4 0.012
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.012
nucleus localization GO:0051647 34 0.012
regulation of peptidase activity GO:0052547 39 0.011
lipid metabolic process GO:0006629 121 0.011
axonogenesis GO:0007409 290 0.011
regulation of protein kinase activity GO:0045859 51 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.011
protein targeting GO:0006605 64 0.011
regulation of protein maturation GO:1903317 32 0.011
positive regulation of developmental process GO:0051094 143 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
regulation of nucleoside metabolic process GO:0009118 50 0.011
macromolecular complex disassembly GO:0032984 37 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
secondary metabolic process GO:0019748 75 0.011
eggshell formation GO:0030703 105 0.011
spindle assembly GO:0051225 80 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.011
regulation of embryonic development GO:0045995 68 0.011
organophosphate catabolic process GO:0046434 112 0.011
actomyosin contractile ring assembly GO:0000915 10 0.011
neuron projection guidance GO:0097485 241 0.010
pronuclear migration GO:0035046 4 0.010
brain development GO:0007420 120 0.010
protein processing GO:0016485 68 0.010
protein localization to organelle GO:0033365 82 0.010
muscle cell differentiation GO:0042692 103 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
non sensory hair organization GO:0035316 47 0.010
gtp metabolic process GO:0046039 72 0.010
positive regulation of filopodium assembly GO:0051491 15 0.010
spindle assembly involved in mitosis GO:0090307 50 0.010

twf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.010