Drosophila melanogaster

97 known processes

geminin (Dmel_CG3183)

CG3183 gene product from transcript CG3183-RA

(Aliases: v(2)k09107,Dm Geminin,Dm geminin,anon-WO0257455.1,l(2)k14019,gem,Geminin,CG3183,Dmel\CG3183,Gem)

geminin biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex biogenesis GO:0070271 201 0.967
Mouse
spindle organization GO:0007051 253 0.958
mitotic spindle organization GO:0007052 220 0.777
positive regulation of transcription dna templated GO:0045893 266 0.766
organelle fission GO:0048285 340 0.702
neuronal stem cell division GO:0036445 35 0.678
mitotic sister chromatid separation GO:0051306 30 0.647
nuclear division GO:0000280 332 0.619
mitotic nuclear division GO:0007067 213 0.543
regulation of mitosis GO:0007088 56 0.528
meiotic nuclear division GO:0007126 151 0.526
transcription from rna polymerase ii promoter GO:0006366 368 0.522
cell division GO:0051301 248 0.519
phosphorylation GO:0016310 294 0.517
small molecule metabolic process GO:0044281 305 0.477
chromosome segregation GO:0007059 157 0.476
sex differentiation GO:0007548 81 0.377
positive regulation of rna metabolic process GO:0051254 271 0.369
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.343
positive regulation of cellular biosynthetic process GO:0031328 316 0.282
reproductive structure development GO:0048608 74 0.278
positive regulation of biosynthetic process GO:0009891 316 0.276
programmed cell death GO:0012501 257 0.273
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.262
development of primary sexual characteristics GO:0045137 50 0.255
genitalia development GO:0048806 26 0.254
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.254
regulation of mitotic cell cycle GO:0007346 190 0.230
cell cycle phase transition GO:0044770 140 0.221
reproductive system development GO:0061458 74 0.219
macromolecular complex assembly GO:0065003 256 0.217
Mouse
regulation of cell division GO:0051302 72 0.214
protein complex assembly GO:0006461 200 0.208
Mouse
compound eye development GO:0048749 307 0.205
regulation of cell cycle phase transition GO:1901987 130 0.199
mitotic cell cycle phase transition GO:0044772 138 0.195
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.192
positive regulation of nucleic acid templated transcription GO:1903508 266 0.185
spindle assembly involved in mitosis GO:0090307 50 0.185
chromosome organization GO:0051276 360 0.184
regulation of organelle organization GO:0033043 196 0.180
proteasomal protein catabolic process GO:0010498 59 0.178
cellular macromolecule catabolic process GO:0044265 136 0.174
regulation of cell cycle process GO:0010564 181 0.174
negative regulation of gene expression GO:0010629 387 0.173
Human Mouse
meiotic cell cycle process GO:1903046 132 0.173
spindle assembly GO:0051225 80 0.167
meiotic cell cycle GO:0051321 171 0.150
chromosome separation GO:0051304 42 0.148
positive regulation of macromolecule metabolic process GO:0010604 405 0.144
positive regulation of gene expression GO:0010628 290 0.143
regulation of programmed cell death GO:0043067 152 0.137
regulation of mitotic sister chromatid segregation GO:0033047 28 0.136
chromosome localization GO:0050000 20 0.133
neuroblast proliferation GO:0007405 74 0.132
modification dependent protein catabolic process GO:0019941 78 0.131
regulation of nuclear division GO:0051783 58 0.130
single organism biosynthetic process GO:0044711 206 0.130
regulation of gene silencing GO:0060968 63 0.130
regulation of mitotic cell cycle phase transition GO:1901990 130 0.126
neuroblast division GO:0055057 35 0.125
mitotic sister chromatid segregation GO:0000070 87 0.121
regulation of sister chromatid segregation GO:0033045 28 0.120
positive regulation of rna biosynthetic process GO:1902680 266 0.119
gonad development GO:0008406 50 0.116
translation GO:0006412 69 0.114
vesicle mediated transport GO:0016192 381 0.112
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.112
regulation of dna metabolic process GO:0051052 34 0.111
regulation of cell death GO:0010941 173 0.096
digestive system development GO:0055123 149 0.092
ubiquitin dependent protein catabolic process GO:0006511 78 0.091
catabolic process GO:0009056 409 0.090
regulation of mitotic sister chromatid separation GO:0010965 28 0.090
regulation of protein metabolic process GO:0051246 256 0.087
gene silencing by rna GO:0031047 57 0.086
regulation of chromosome segregation GO:0051983 32 0.086
sister chromatid segregation GO:0000819 92 0.086
enzyme linked receptor protein signaling pathway GO:0007167 179 0.083
regulation of cell cycle GO:0051726 291 0.079
regulation of meiosis GO:0040020 3 0.078
regulation of chromosome organization GO:0033044 64 0.078
cellular protein modification process GO:0006464 438 0.076
dendrite morphogenesis GO:0048813 199 0.074
establishment of localization in cell GO:0051649 402 0.072
negative regulation of phosphorus metabolic process GO:0010563 45 0.071
carboxylic acid metabolic process GO:0019752 92 0.067
negative regulation of cell cycle GO:0045786 116 0.067
Human Mouse
oocyte differentiation GO:0009994 145 0.067
negative regulation of cellular metabolic process GO:0031324 382 0.065
regulation of cellular protein metabolic process GO:0032268 243 0.065
intracellular signal transduction GO:0035556 300 0.062
modification dependent macromolecule catabolic process GO:0043632 79 0.059
negative regulation of phosphate metabolic process GO:0045936 45 0.059
positive regulation of phosphorylation GO:0042327 87 0.055
positive regulation of signal transduction GO:0009967 223 0.054
g2 m transition of mitotic cell cycle GO:0000086 19 0.054
posttranscriptional gene silencing GO:0016441 46 0.054
endocytosis GO:0006897 310 0.053
regulation of cellular catabolic process GO:0031329 157 0.053
positive regulation of cell communication GO:0010647 250 0.051
regulation of heterochromatin assembly GO:0031445 8 0.050
organic substance catabolic process GO:1901575 308 0.050
chromosome movement towards spindle pole GO:0051305 4 0.050
positive regulation of signaling GO:0023056 243 0.049
positive regulation of protein metabolic process GO:0051247 128 0.049
oxoacid metabolic process GO:0043436 103 0.047
cytoplasmic microtubule organization GO:0031122 22 0.044
organelle assembly GO:0070925 198 0.043
Zebrafish
posttranscriptional regulation of gene expression GO:0010608 145 0.040
negative regulation of organelle organization GO:0010639 56 0.039
negative regulation of mitotic cell cycle GO:0045930 109 0.039
stem cell division GO:0017145 69 0.037
stem cell proliferation GO:0072089 88 0.037
single organism catabolic process GO:0044712 228 0.037
small gtpase mediated signal transduction GO:0007264 88 0.036
metaphase anaphase transition of cell cycle GO:0044784 28 0.036
positive regulation of response to stimulus GO:0048584 323 0.036
body morphogenesis GO:0010171 2 0.035
protein catabolic process GO:0030163 101 0.035
regulation of apoptotic process GO:0042981 130 0.034
signal transduction by phosphorylation GO:0023014 107 0.034
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.034
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.033
organic acid metabolic process GO:0006082 103 0.033
posttranscriptional gene silencing by rna GO:0035194 45 0.032
proteolysis GO:0006508 192 0.032
regionalization GO:0003002 416 0.030
protein phosphorylation GO:0006468 169 0.030
establishment of chromosome localization GO:0051303 20 0.028
purine ribonucleotide catabolic process GO:0009154 109 0.027
morphogenesis of an epithelium GO:0002009 276 0.027
regulation of molecular function GO:0065009 217 0.026
positive regulation of cellular catabolic process GO:0031331 95 0.026
mitotic cell cycle checkpoint GO:0007093 88 0.026
response to abiotic stimulus GO:0009628 341 0.026
organelle localization GO:0051640 148 0.026
eye development GO:0001654 323 0.026
neural precursor cell proliferation GO:0061351 75 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.025
nucleus organization GO:0006997 45 0.025
regulation of gene expression epigenetic GO:0040029 128 0.025
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.025
microtubule organizing center organization GO:0031023 168 0.024
anatomical structure homeostasis GO:0060249 97 0.024
aromatic compound catabolic process GO:0019439 166 0.023
tube morphogenesis GO:0035239 191 0.023
macromolecule catabolic process GO:0009057 161 0.023
negative regulation of signaling GO:0023057 219 0.023
regulation of intracellular signal transduction GO:1902531 236 0.022
positive regulation of cell proliferation GO:0008284 47 0.022
endomitotic cell cycle GO:0007113 7 0.022
mitotic sister chromatid cohesion GO:0007064 6 0.022
regulation of phosphatase activity GO:0010921 3 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
cellular macromolecular complex assembly GO:0034622 153 0.022
regulation of catabolic process GO:0009894 170 0.022
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.021
cell death GO:0008219 279 0.021
organophosphate catabolic process GO:0046434 112 0.021
g1 s transition of mitotic cell cycle GO:0000082 31 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.021
regulation of phosphorylation GO:0042325 147 0.021
regulation of transport GO:0051049 181 0.020
oocyte development GO:0048599 124 0.020
negative regulation of apoptotic process GO:0043066 63 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.019
developmental programmed cell death GO:0010623 138 0.019
phagocytosis GO:0006909 215 0.019
positive regulation of lipid catabolic process GO:0050996 1 0.018
larval development GO:0002164 104 0.017
organophosphate metabolic process GO:0019637 195 0.017
response to biotic stimulus GO:0009607 294 0.017
gene silencing GO:0016458 138 0.017
regulation of cellular response to stress GO:0080135 89 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.017
dna metabolic process GO:0006259 227 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
regulation of cell cycle g1 s phase transition GO:1902806 23 0.016
mitotic spindle elongation GO:0000022 81 0.016
receptor mediated endocytosis GO:0006898 21 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
regulation of proteasomal protein catabolic process GO:0061136 39 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
regulation of localization GO:0032879 275 0.016
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.016
regulation of catalytic activity GO:0050790 185 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
negative regulation of transcription factor import into nucleus GO:0042992 4 0.015
death GO:0016265 284 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
gland development GO:0048732 191 0.014
Zebrafish
negative regulation of protein metabolic process GO:0051248 85 0.014
spindle elongation GO:0051231 83 0.014
nucleus localization GO:0051647 34 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
cell cycle dna replication GO:0044786 23 0.014
negative regulation of cell communication GO:0010648 223 0.014
organonitrogen compound metabolic process GO:1901564 318 0.013
intracellular transport GO:0046907 228 0.013
peptidyl amino acid modification GO:0018193 105 0.013
protein modification process GO:0036211 438 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
nitric oxide metabolic process GO:0046209 1 0.013
regulation of proteolysis GO:0030162 87 0.013
centrosome organization GO:0051297 163 0.013
reproductive behavior GO:0019098 122 0.013
dna hypermethylation GO:0044026 3 0.013
salivary gland development GO:0007431 162 0.013
reactive oxygen species biosynthetic process GO:1903409 0 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
cell cycle checkpoint GO:0000075 95 0.012
purine containing compound metabolic process GO:0072521 155 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
Human Mouse
regulation of syncytial blastoderm mitotic cell cycle GO:0007348 4 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
dna replication initiation GO:0006270 6 0.012
regulation of striated muscle contraction GO:0006942 2 0.012
covalent chromatin modification GO:0016569 106 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
positive regulation of cell death GO:0010942 69 0.012
positive regulation of catabolic process GO:0009896 105 0.012
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.012
cellular response to nutrient GO:0031670 1 0.012
epithelial tube morphogenesis GO:0060562 88 0.012
anterior posterior pattern specification GO:0009952 136 0.012
regulation of kinase activity GO:0043549 53 0.012
regulation of transferase activity GO:0051338 58 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
immune system development GO:0002520 57 0.012
positive regulation of binding GO:0051099 4 0.011
gene silencing by mirna GO:0035195 22 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
apoptotic process GO:0006915 159 0.011
negative regulation of cell death GO:0060548 81 0.011
cellular catabolic process GO:0044248 372 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
Human Mouse
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.011
mitochondrial membrane organization GO:0007006 3 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
meiotic cell cycle phase transition GO:0044771 4 0.011
demethylation GO:0070988 6 0.011
dendrite development GO:0016358 204 0.011
multi multicellular organism process GO:0044706 123 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
muscle cell differentiation GO:0042692 103 0.010
prostanoid biosynthetic process GO:0046457 1 0.010
nucleoside monophosphate metabolic process GO:0009123 52 0.010
negative regulation of gtp catabolic process GO:0033125 1 0.010
regulation of hydrolase activity GO:0051336 97 0.010
ovarian follicle cell development GO:0030707 248 0.010
cell proliferation GO:0008283 299 0.010

geminin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
syndrome DOID:225 0 0.014
brachydactyly DOID:0050581 0 0.011
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011
disease of anatomical entity DOID:7 0 0.011
dysostosis DOID:1934 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011