Drosophila melanogaster

5 known processes

Tif-IA (Dmel_CG3278)

CG3278 gene product from transcript CG3278-RA

(Aliases: TifIA,CG3278,dTIF-IA,Dmel\CG3278,TIF-1A,Tif-1A,TIF-IA,CG16938,CG5951)

Tif-IA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 302 0.749
positive regulation of biosynthetic process GO:0009891 316 0.490
Mouse
protein localization GO:0008104 284 0.473
cellular macromolecule localization GO:0070727 220 0.424
single organism cellular localization GO:1902580 180 0.402
cardiovascular system development GO:0072358 82 0.372
establishment of localization in cell GO:0051649 402 0.273
protein transport GO:0015031 155 0.258
protein complex biogenesis GO:0070271 201 0.239
Mouse
nuclear transport GO:0051169 72 0.216
positive regulation of rna biosynthetic process GO:1902680 266 0.198
Mouse
protein targeting GO:0006605 64 0.181
positive regulation of macromolecule metabolic process GO:0010604 405 0.179
Mouse
establishment of protein localization GO:0045184 163 0.156
intracellular transport GO:0046907 228 0.152
positive regulation of rna metabolic process GO:0051254 271 0.140
Mouse
cellular protein localization GO:0034613 160 0.137
single organism intracellular transport GO:1902582 207 0.132
positive regulation of cellular protein metabolic process GO:0032270 118 0.121
organic substance transport GO:0071702 257 0.118
eye development GO:0001654 323 0.113
cytoplasmic transport GO:0016482 130 0.111
cytoplasm organization GO:0007028 64 0.108
Mouse
muscle cell differentiation GO:0042692 103 0.106
positive regulation of nucleic acid templated transcription GO:1903508 266 0.106
Mouse
eye morphogenesis GO:0048592 260 0.089
cellular protein complex assembly GO:0043623 71 0.085
compound eye morphogenesis GO:0001745 249 0.080
nuclear export GO:0051168 24 0.079
multicellular organism growth GO:0035264 46 0.073
macromolecular complex assembly GO:0065003 256 0.073
Mouse
nucleocytoplasmic transport GO:0006913 72 0.067
larval development GO:0002164 104 0.066
single organism membrane organization GO:0044802 93 0.065
protein complex assembly GO:0006461 200 0.061
Mouse
establishment of protein localization to organelle GO:0072594 62 0.061
cell death GO:0008219 279 0.059
Mouse
hemopoiesis GO:0030097 46 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.058
Mouse
death GO:0016265 284 0.055
Mouse
programmed cell death GO:0012501 257 0.055
Mouse
mitochondrion organization GO:0007005 65 0.054
positive regulation of cellular biosynthetic process GO:0031328 316 0.052
Mouse
protein localization to organelle GO:0033365 82 0.052
developmental growth GO:0048589 280 0.052
apoptotic process GO:0006915 159 0.050
Mouse
gland development GO:0048732 191 0.050
regulation of multicellular organismal development GO:2000026 414 0.049
translation GO:0006412 69 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.047
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.046
Mouse
regulation of cell proliferation GO:0042127 163 0.046
regulation of nervous system development GO:0051960 248 0.043
regulation of programmed cell death GO:0043067 152 0.043
Mouse
regulation of apoptotic process GO:0042981 130 0.042
Mouse
stem cell maintenance GO:0019827 67 0.042
embryo development ending in birth or egg hatching GO:0009792 152 0.040
Mouse
positive regulation of protein metabolic process GO:0051247 128 0.038
hematopoietic or lymphoid organ development GO:0048534 57 0.037
phagocytosis GO:0006909 215 0.036
exocrine system development GO:0035272 162 0.035
regulation of cellular protein metabolic process GO:0032268 243 0.034
compound eye development GO:0048749 307 0.034
immune system process GO:0002376 347 0.033
regulation of localization GO:0032879 275 0.033
vesicle mediated transport GO:0016192 381 0.033
gland morphogenesis GO:0022612 145 0.033
rrna processing GO:0006364 3 0.032
sensory organ morphogenesis GO:0090596 260 0.031
positive regulation of gene expression GO:0010628 290 0.029
Mouse
morphogenesis of an epithelium GO:0002009 276 0.029
nuclear import GO:0051170 51 0.029
cellular component disassembly GO:0022411 46 0.028
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.028
Mouse
stem cell division GO:0017145 69 0.028
membrane organization GO:0061024 112 0.027
stem cell development GO:0048864 79 0.027
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.027
Mouse
ribonucleoprotein complex disassembly GO:0032988 1 0.026
protein modification process GO:0036211 438 0.026
cellular macromolecular complex assembly GO:0034622 153 0.026
g2 dna damage checkpoint GO:0031572 69 0.024
regulation of meiosis GO:0040020 3 0.024
positive regulation of cell growth GO:0030307 19 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
reproductive behavior GO:0019098 122 0.023
growth GO:0040007 359 0.023
regulation of immune system process GO:0002682 176 0.023
chromatin modification GO:0016568 147 0.023
proteolysis GO:0006508 192 0.022
ribonucleoprotein complex biogenesis GO:0022613 31 0.022
regulation of growth GO:0040008 233 0.021
body morphogenesis GO:0010171 2 0.021
positive regulation of translation GO:0045727 12 0.021
salivary gland morphogenesis GO:0007435 145 0.021
asymmetric stem cell division GO:0098722 49 0.021
positive regulation of developmental growth GO:0048639 62 0.021
multicellular organismal aging GO:0010259 140 0.020
rna processing GO:0006396 147 0.020
actin filament organization GO:0007015 126 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
intracellular protein transport GO:0006886 104 0.020
protein ubiquitination GO:0016567 70 0.019
regulation of organelle organization GO:0033043 196 0.019
regulation of protein metabolic process GO:0051246 256 0.019
neural retina development GO:0003407 4 0.018
regulation of hemocyte proliferation GO:0035206 37 0.018
circulatory system development GO:0072359 82 0.017
single organism nuclear import GO:1902593 51 0.017
regulation of oocyte development GO:0060281 27 0.017
cellular protein modification process GO:0006464 438 0.016
rna catabolic process GO:0006401 37 0.016
gene silencing by mirna GO:0035195 22 0.016
intermediate filament based process GO:0045103 1 0.016
response to external biotic stimulus GO:0043207 293 0.016
salivary gland development GO:0007431 162 0.015
salivary gland histolysis GO:0035070 88 0.015
regulation of developmental growth GO:0048638 174 0.015
negative regulation of gene expression GO:0010629 387 0.015
cellular amine metabolic process GO:0044106 12 0.014
negative regulation of developmental process GO:0051093 201 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
protein import GO:0017038 55 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
regulation of cell cycle process GO:0010564 181 0.014
regulation of translation GO:0006417 56 0.013
translational termination GO:0006415 2 0.013
intermediate filament cytoskeleton organization GO:0045104 1 0.013
nuclear division GO:0000280 332 0.013
immune system development GO:0002520 57 0.013
mrna metabolic process GO:0016071 124 0.013
negative regulation of phosphatase activity GO:0010923 3 0.013
regulation of histone methylation GO:0031060 10 0.012
protein export from nucleus GO:0006611 10 0.012
cellular catabolic process GO:0044248 372 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
homeostatic process GO:0042592 199 0.011
Mouse
mrna polyadenylation GO:0006378 11 0.011
establishment of organelle localization GO:0051656 122 0.011
locomotory behavior GO:0007626 176 0.011
protein targeting to nucleus GO:0044744 51 0.011
macromolecule catabolic process GO:0009057 161 0.011
regulation of protein modification process GO:0031399 112 0.011
phosphorylation GO:0016310 294 0.011
negative regulation of growth GO:0045926 84 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
organelle localization GO:0051640 148 0.011
regulation of signal transduction by p53 class mediator GO:1901796 1 0.010
Mouse
multi organism reproductive behavior GO:0044705 121 0.010
pole plasm oskar mrna localization GO:0045451 46 0.010
positive regulation of molecular function GO:0044093 136 0.010
positive regulation of viral process GO:0048524 2 0.010

Tif-IA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
osteogenesis imperfecta DOID:12347 0 0.023
disease of anatomical entity DOID:7 0 0.023
bone disease DOID:0080001 0 0.023
musculoskeletal system disease DOID:17 0 0.023
bone development disease DOID:0080006 0 0.023
connective tissue disease DOID:65 0 0.023
osteochondrodysplasia DOID:2256 0 0.023
syndrome DOID:225 0 0.013
benign neoplasm DOID:0060072 0 0.010
disease of cellular proliferation DOID:14566 0 0.010