Drosophila melanogaster

54 known processes

SdhB (Dmel_CG3283)

Succinate dehydrogenase B

(Aliases: sdhB,Ip,CG3283,SDH-Ip,Dmel\CG3283,SDHb,SDH,SDH-IP)

SdhB biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to oxidative stress GO:0006979 86 0.906
oxidative phosphorylation GO:0006119 9 0.831
oxidation reduction process GO:0055114 123 0.810
cellular respiration GO:0045333 26 0.761
generation of precursor metabolites and energy GO:0006091 42 0.581
nucleoside triphosphate metabolic process GO:0009141 120 0.572
purine nucleoside monophosphate metabolic process GO:0009126 50 0.511
nucleotide metabolic process GO:0009117 161 0.456
atp metabolic process GO:0046034 49 0.430
ribonucleoside monophosphate metabolic process GO:0009161 51 0.406
energy derivation by oxidation of organic compounds GO:0015980 32 0.342
respiratory electron transport chain GO:0022904 11 0.313
response to abiotic stimulus GO:0009628 341 0.290
purine ribonucleoside metabolic process GO:0046128 127 0.285
atp synthesis coupled electron transport GO:0042773 8 0.279
organonitrogen compound metabolic process GO:1901564 318 0.275
purine containing compound metabolic process GO:0072521 155 0.244
purine nucleoside metabolic process GO:0042278 127 0.233
nucleoside monophosphate metabolic process GO:0009123 52 0.222
embryo development ending in birth or egg hatching GO:0009792 152 0.221
immune response GO:0006955 246 0.215
response to oxygen radical GO:0000305 3 0.209
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.209
mitochondrion organization GO:0007005 65 0.204
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.195
programmed cell death GO:0012501 257 0.187
response to reactive oxygen species GO:0000302 24 0.183
defense response GO:0006952 300 0.176
aging GO:0007568 143 0.173
larval development GO:0002164 104 0.172
ribonucleoside triphosphate metabolic process GO:0009199 119 0.165
carbohydrate derivative metabolic process GO:1901135 217 0.155
ribose phosphate metabolic process GO:0019693 145 0.151
reactive oxygen species metabolic process GO:0072593 22 0.149
phosphorylation GO:0016310 294 0.145
glycosyl compound metabolic process GO:1901657 127 0.140
multicellular organismal aging GO:0010259 140 0.139
response to oxygen containing compound GO:1901700 200 0.128
purine ribonucleotide metabolic process GO:0009150 145 0.128
mitochondrial atp synthesis coupled electron transport GO:0042775 8 0.126
cellular response to reactive oxygen species GO:0034614 14 0.121
nucleoside phosphate metabolic process GO:0006753 162 0.119
determination of adult lifespan GO:0008340 137 0.117
electron transport chain GO:0022900 14 0.111
response to light stimulus GO:0009416 124 0.104
single organism biosynthetic process GO:0044711 206 0.104
response to other organism GO:0051707 293 0.102
response to hydrogen peroxide GO:0042542 11 0.101
response to nutrient levels GO:0031667 114 0.099
protein complex assembly GO:0006461 200 0.096
cellular response to chemical stimulus GO:0070887 199 0.095
protein complex biogenesis GO:0070271 201 0.092
nucleobase containing small molecule metabolic process GO:0055086 174 0.088
regulation of cell differentiation GO:0045595 302 0.083
cell death GO:0008219 279 0.083
adult locomotory behavior GO:0008344 76 0.082
purine nucleoside triphosphate metabolic process GO:0009144 119 0.079
neurological system process GO:0050877 358 0.077
ribonucleoside metabolic process GO:0009119 127 0.077
single organism behavior GO:0044708 391 0.072
anatomical structure homeostasis GO:0060249 97 0.067
apoptotic process GO:0006915 159 0.065
locomotory behavior GO:0007626 176 0.065
ribonucleotide metabolic process GO:0009259 145 0.064
death GO:0016265 284 0.062
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.061
vesicle mediated transport GO:0016192 381 0.061
endocytosis GO:0006897 310 0.060
growth GO:0040007 359 0.059
cation homeostasis GO:0055080 51 0.059
small molecule metabolic process GO:0044281 305 0.058
cellular response to oxidative stress GO:0034599 28 0.056
wound healing GO:0042060 75 0.055
response to external biotic stimulus GO:0043207 293 0.052
immune system process GO:0002376 347 0.051
cellular protein complex assembly GO:0043623 71 0.050
sperm mitochondrion organization GO:0030382 7 0.049
purine containing compound biosynthetic process GO:0072522 30 0.048
negative regulation of developmental process GO:0051093 201 0.048
regulation of multicellular organismal development GO:2000026 414 0.047
organophosphate metabolic process GO:0019637 195 0.047
homeostatic process GO:0042592 199 0.044
response to inorganic substance GO:0010035 44 0.042
response to radiation GO:0009314 155 0.041
ribonucleoside biosynthetic process GO:0042455 3 0.040
eye development GO:0001654 323 0.040
response to wounding GO:0009611 94 0.040
ribose phosphate biosynthetic process GO:0046390 28 0.039
atp biosynthetic process GO:0006754 2 0.038
regulation of response to oxidative stress GO:1902882 4 0.038
taxis GO:0042330 304 0.037
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.037
regulation of cell development GO:0060284 215 0.036
purine nucleotide metabolic process GO:0006163 146 0.035
regulation of cell death GO:0010941 173 0.035
membrane organization GO:0061024 112 0.035
nucleoside phosphate biosynthetic process GO:1901293 34 0.035
regulation of cellular amine metabolic process GO:0033238 3 0.033
negative regulation of response to stimulus GO:0048585 258 0.033
digestive system development GO:0055123 149 0.031
regulation of cellular response to oxidative stress GO:1900407 4 0.031
regulation of protein metabolic process GO:0051246 256 0.031
digestive tract morphogenesis GO:0048546 127 0.030
cellular macromolecular complex assembly GO:0034622 153 0.030
macromolecular complex assembly GO:0065003 256 0.029
single organism catabolic process GO:0044712 228 0.029
purine ribonucleoside biosynthetic process GO:0046129 3 0.029
purine ribonucleotide biosynthetic process GO:0009152 28 0.028
intracellular signal transduction GO:0035556 300 0.027
regulation of anatomical structure morphogenesis GO:0022603 242 0.027
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.026
response to organic substance GO:0010033 284 0.024
gland development GO:0048732 191 0.024
transmembrane transport GO:0055085 139 0.024
regulation of phosphate metabolic process GO:0019220 210 0.024
innate immune response GO:0045087 144 0.024
purine nucleoside biosynthetic process GO:0042451 3 0.024
negative regulation of response to oxidative stress GO:1902883 1 0.024
response to bacterium GO:0009617 198 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
negative regulation of programmed cell death GO:0043069 72 0.023
age dependent response to oxidative stress GO:0001306 3 0.023
regulation of mitochondrial membrane potential GO:0051881 2 0.022
nucleoside metabolic process GO:0009116 127 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
regulation of intracellular signal transduction GO:1902531 236 0.021
brain development GO:0007420 120 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
developmental programmed cell death GO:0010623 138 0.021
sensory perception GO:0007600 196 0.021
response to starvation GO:0042594 97 0.021
organic acid metabolic process GO:0006082 103 0.021
defense response to other organism GO:0098542 225 0.020
actin filament based process GO:0030029 220 0.020
cellular response to oxygen containing compound GO:1901701 79 0.020
response to biotic stimulus GO:0009607 294 0.019
positive regulation of cell communication GO:0010647 250 0.019
negative regulation of reactive oxygen species metabolic process GO:2000378 1 0.019
mitochondrion degradation GO:0000422 8 0.019
regulation of developmental growth GO:0048638 174 0.019
positive regulation of signal transduction GO:0009967 223 0.018
positive regulation of signaling GO:0023056 243 0.018
hematopoietic or lymphoid organ development GO:0048534 57 0.018
developmental growth GO:0048589 280 0.018
mitochondrial fusion GO:0008053 7 0.018
regulation of catalytic activity GO:0050790 185 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
response to organic cyclic compound GO:0014070 89 0.017
cation transport GO:0006812 110 0.017
positive regulation of developmental process GO:0051094 143 0.017
negative regulation of cell death GO:0060548 81 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
carbohydrate derivative biosynthetic process GO:1901137 85 0.017
negative regulation of cell proliferation GO:0008285 69 0.017
negative regulation of cellular response to oxidative stress GO:1900408 1 0.017
g protein coupled receptor signaling pathway GO:0007186 136 0.016
regulation of immune system process GO:0002682 176 0.016
negative regulation of signal transduction GO:0009968 206 0.016
hemopoiesis GO:0030097 46 0.016
digestive tract development GO:0048565 149 0.016
regulation of neurogenesis GO:0050767 158 0.016
central nervous system development GO:0007417 201 0.016
nucleoside triphosphate catabolic process GO:0009143 108 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
atp catabolic process GO:0006200 38 0.015
regulation of apoptotic process GO:0042981 130 0.015
salivary gland development GO:0007431 162 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
synaptic transmission GO:0007268 288 0.015
positive regulation of proteolysis GO:0045862 52 0.015
phagocytosis GO:0006909 215 0.015
somatic muscle development GO:0007525 66 0.015
glycosyl compound biosynthetic process GO:1901659 3 0.014
defense response to bacterium GO:0042742 178 0.014
camera type eye development GO:0043010 4 0.014
imaginal disc pattern formation GO:0007447 91 0.014
actin filament organization GO:0007015 126 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
regulation of molecular function GO:0065009 217 0.013
paracrine signaling GO:0038001 7 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
citrate metabolic process GO:0006101 0 0.013
nucleoside biosynthetic process GO:0009163 3 0.013
ribonucleotide biosynthetic process GO:0009260 28 0.013
purine nucleotide biosynthetic process GO:0006164 29 0.013
mitochondrion morphogenesis GO:0070584 8 0.013
regionalization GO:0003002 416 0.012
nicotinamide nucleotide metabolic process GO:0046496 2 0.012
regulation of cell proliferation GO:0042127 163 0.012
cellular homeostasis GO:0019725 80 0.012
chemical homeostasis GO:0048878 92 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
response to extracellular stimulus GO:0009991 116 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
oxoacid metabolic process GO:0043436 103 0.011
multicellular organism growth GO:0035264 46 0.011
chemotaxis GO:0006935 249 0.011
cytoplasmic microtubule organization GO:0031122 22 0.011
regulation of membrane potential GO:0042391 35 0.011
positive regulation of viral process GO:0048524 2 0.011
negative regulation of defense response GO:0031348 35 0.011
head development GO:0060322 135 0.011
negative regulation of signaling GO:0023057 219 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.011
organic substance catabolic process GO:1901575 308 0.010
metal ion homeostasis GO:0055065 44 0.010
positive regulation of molecular function GO:0044093 136 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010
dendrite development GO:0016358 204 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
negative regulation of cell communication GO:0010648 223 0.010

SdhB disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.031
Human
disease of anatomical entity DOID:7 0 0.025
cancer DOID:162 0 0.019
Human
organ system cancer DOID:0050686 0 0.019
Human
nervous system disease DOID:863 0 0.010
immune system disease DOID:2914 0 0.010