Drosophila melanogaster

25 known processes

inaE (Dmel_CG33174)

inactivation no afterpotential E

(Aliases: CG15761,EP(X)1101,CG33174,CG11096,CG11104,CG32630,CG11102,Dmel\CG33174)

inaE biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 137 0.364
g protein coupled receptor signaling pathway GO:0007186 136 0.341
photoreceptor cell differentiation GO:0046530 170 0.317
sensory organ morphogenesis GO:0090596 260 0.281
response to radiation GO:0009314 155 0.252
eye morphogenesis GO:0048592 260 0.220
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.218
death GO:0016265 284 0.211
compound eye morphogenesis GO:0001745 249 0.199
aging GO:0007568 143 0.184
response to light stimulus GO:0009416 124 0.181
eye development GO:0001654 323 0.164
compound eye development GO:0048749 307 0.163
epithelial cell differentiation GO:0030855 322 0.160
negative regulation of multicellular organismal process GO:0051241 142 0.155
compound eye photoreceptor development GO:0042051 78 0.153
multicellular organismal aging GO:0010259 140 0.152
response to oxidative stress GO:0006979 86 0.145
regulation of cell development GO:0060284 215 0.139
intracellular signal transduction GO:0035556 300 0.118
post embryonic appendage morphogenesis GO:0035120 385 0.115
response to abiotic stimulus GO:0009628 341 0.109
compound eye photoreceptor cell differentiation GO:0001751 140 0.107
programmed cell death GO:0012501 257 0.105
wing disc morphogenesis GO:0007472 344 0.099
photoreceptor cell development GO:0042461 96 0.098
embryonic morphogenesis GO:0048598 206 0.095
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.093
eye photoreceptor cell differentiation GO:0001754 145 0.088
positive regulation of biosynthetic process GO:0009891 316 0.087
signal transduction by phosphorylation GO:0023014 107 0.083
cytoplasmic transport GO:0016482 130 0.083
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.080
positive regulation of cell death GO:0010942 69 0.080
neuron death GO:0070997 27 0.080
purine containing compound biosynthetic process GO:0072522 30 0.079
negative regulation of developmental process GO:0051093 201 0.077
epithelial cell development GO:0002064 274 0.076
intracellular transport GO:0046907 228 0.075
negative regulation of cell communication GO:0010648 223 0.074
appendage development GO:0048736 401 0.073
positive regulation of cellular biosynthetic process GO:0031328 316 0.073
imaginal disc derived appendage morphogenesis GO:0035114 395 0.072
tissue morphogenesis GO:0048729 297 0.072
regulation of cell death GO:0010941 173 0.071
phosphorylation GO:0016310 294 0.070
establishment of localization in cell GO:0051649 402 0.067
cellular response to light stimulus GO:0071482 37 0.065
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.060
chorion containing eggshell formation GO:0007304 105 0.059
nucleoside phosphate biosynthetic process GO:1901293 34 0.057
regulation of anatomical structure size GO:0090066 163 0.057
regulation of multicellular organismal development GO:2000026 414 0.056
immune system process GO:0002376 347 0.056
single organism intracellular transport GO:1902582 207 0.056
regionalization GO:0003002 416 0.055
organonitrogen compound biosynthetic process GO:1901566 117 0.055
regulation of nervous system development GO:0051960 248 0.054
regulation of apoptotic process GO:0042981 130 0.054
cell death GO:0008219 279 0.052
positive regulation of cell communication GO:0010647 250 0.051
cell growth GO:0016049 108 0.049
phototransduction visible light GO:0007603 27 0.049
protein transport GO:0015031 155 0.049
forebrain development GO:0030900 2 0.048
organic substance transport GO:0071702 257 0.048
ovarian follicle cell development GO:0030707 248 0.048
growth GO:0040007 359 0.047
homeostatic process GO:0042592 199 0.045
regulation of response to external stimulus GO:0032101 115 0.045
transposition rna mediated GO:0032197 3 0.044
single organism behavior GO:0044708 391 0.043
jnk cascade GO:0007254 50 0.043
regulation of intracellular signal transduction GO:1902531 236 0.041
regulation of neuron death GO:1901214 26 0.041
stress activated mapk cascade GO:0051403 52 0.041
columnar cuboidal epithelial cell development GO:0002066 249 0.041
carbohydrate derivative biosynthetic process GO:1901137 85 0.040
ribose phosphate biosynthetic process GO:0046390 28 0.039
small gtpase mediated signal transduction GO:0007264 88 0.038
apoptotic process GO:0006915 159 0.038
response to biotic stimulus GO:0009607 294 0.038
eggshell chorion assembly GO:0007306 66 0.038
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.038
ameboidal type cell migration GO:0001667 151 0.038
cell proliferation GO:0008283 299 0.037
detection of abiotic stimulus GO:0009582 66 0.037
mapk cascade GO:0000165 107 0.037
regulation of mapk cascade GO:0043408 92 0.037
camera type eye development GO:0043010 4 0.036
establishment or maintenance of cell polarity GO:0007163 167 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.036
regulation of protein transport GO:0051223 57 0.036
ras protein signal transduction GO:0007265 88 0.035
imaginal disc derived appendage development GO:0048737 399 0.035
dephosphorylation GO:0016311 51 0.034
response to uv GO:0009411 24 0.034
protein import into nucleus GO:0006606 51 0.034
morphogenesis of a polarized epithelium GO:0001738 93 0.033
negative regulation of signaling GO:0023057 219 0.033
synaptic transmission GO:0007268 288 0.032
regulation of cellular response to stress GO:0080135 89 0.032
phototransduction GO:0007602 52 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
regulation of cell differentiation GO:0045595 302 0.031
head development GO:0060322 135 0.030
regulation of programmed cell death GO:0043067 152 0.030
detection of external stimulus GO:0009581 66 0.030
tissue migration GO:0090130 155 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
regulation of response to stress GO:0080134 200 0.030
regulation of jnk cascade GO:0046328 40 0.030
ribonucleotide biosynthetic process GO:0009260 28 0.029
regulation of behavior GO:0050795 75 0.029
nuclear body organization GO:0030575 6 0.029
regulation of growth GO:0040008 233 0.029
actin filament based process GO:0030029 220 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
purine nucleotide biosynthetic process GO:0006164 29 0.028
epithelial cell migration GO:0010631 148 0.027
positive regulation of programmed cell death GO:0043068 62 0.027
regulation of cell size GO:0008361 63 0.027
eye photoreceptor cell development GO:0042462 81 0.026
nucleotide metabolic process GO:0009117 161 0.026
learning or memory GO:0007611 141 0.026
regulation of stress activated mapk cascade GO:0032872 41 0.026
imaginal disc derived wing morphogenesis GO:0007476 337 0.026
positive regulation of rna metabolic process GO:0051254 271 0.025
positive regulation of transcription dna templated GO:0045893 266 0.025
single organism biosynthetic process GO:0044711 206 0.025
nucleotide biosynthetic process GO:0009165 34 0.024
regulation of neurogenesis GO:0050767 158 0.024
retina development in camera type eye GO:0060041 4 0.024
positive regulation of cell migration GO:0030335 2 0.024
cyclic purine nucleotide metabolic process GO:0052652 25 0.024
purine ribonucleotide biosynthetic process GO:0009152 28 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
positive regulation of signaling GO:0023056 243 0.023
intracellular protein transport GO:0006886 104 0.023
regulation of localization GO:0032879 275 0.023
d amino acid transport GO:0042940 1 0.023
cell aging GO:0007569 2 0.023
positive regulation of rna biosynthetic process GO:1902680 266 0.023
r7 cell differentiation GO:0045466 43 0.023
phagocytosis GO:0006909 215 0.023
response to insulin GO:0032868 29 0.023
positive regulation of gene expression GO:0010628 290 0.022
cellular response to abiotic stimulus GO:0071214 58 0.022
olfactory learning GO:0008355 56 0.022
cellular protein modification process GO:0006464 438 0.022
regulation of immune response GO:0050776 118 0.022
detection of visible light GO:0009584 38 0.022
response to oxygen radical GO:0000305 3 0.022
cellular macromolecule localization GO:0070727 220 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
cell migration GO:0016477 238 0.021
open tracheal system development GO:0007424 204 0.021
response to superoxide GO:0000303 3 0.021
cellular response to oxidative stress GO:0034599 28 0.021
eggshell formation GO:0030703 105 0.021
single organism cellular localization GO:1902580 180 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
ion transmembrane transport GO:0034220 122 0.021
response to reactive oxygen species GO:0000302 24 0.021
response to other organism GO:0051707 293 0.021
localization of cell GO:0051674 257 0.021
regulation of protein metabolic process GO:0051246 256 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.020
terminal region determination GO:0007362 25 0.020
protein modification process GO:0036211 438 0.020
neuron fate commitment GO:0048663 50 0.020
skeletal muscle organ development GO:0060538 48 0.020
morphogenesis of an epithelium GO:0002009 276 0.020
negative regulation of intracellular signal transduction GO:1902532 57 0.020
regulation of cellular component size GO:0032535 98 0.020
regulation of cellular response to insulin stimulus GO:1900076 17 0.020
dorsal appendage formation GO:0046843 47 0.020
myotube cell development GO:0014904 3 0.019
rhodopsin mediated signaling pathway GO:0016056 21 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
energy taxis GO:0009453 21 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
response to temperature stimulus GO:0009266 106 0.019
oocyte development GO:0048599 124 0.019
regulation of intracellular transport GO:0032386 64 0.019
positive regulation of developmental process GO:0051094 143 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
regulation of intracellular protein transport GO:0033157 46 0.018
larval development GO:0002164 104 0.018
humoral immune response GO:0006959 117 0.018
cellular response to radiation GO:0071478 52 0.017
epithelium migration GO:0090132 148 0.017
regulation of ras gtpase activity GO:0032318 38 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
regulation of catalytic activity GO:0050790 185 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
appendage morphogenesis GO:0035107 397 0.017
oxidation reduction process GO:0055114 123 0.017
body morphogenesis GO:0010171 2 0.017
cell projection assembly GO:0030031 94 0.017
cellular response to oxygen containing compound GO:1901701 79 0.017
macromolecular complex assembly GO:0065003 256 0.017
locomotory behavior GO:0007626 176 0.017
respiratory system development GO:0060541 213 0.017
histolysis GO:0007559 102 0.017
vesicle mediated transport GO:0016192 381 0.017
regulation of cytoplasmic transport GO:1903649 47 0.017
regulation of phosphorylation GO:0042325 147 0.017
developmental maturation GO:0021700 172 0.016
negative regulation of growth GO:0045926 84 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
morphogenesis of embryonic epithelium GO:0016331 94 0.016
chemosensory behavior GO:0007635 106 0.016
muscle structure development GO:0061061 224 0.016
nuclear import GO:0051170 51 0.016
positive regulation of mapk cascade GO:0043410 63 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.016
negative regulation of cell proliferation GO:0008285 69 0.016
gland development GO:0048732 191 0.016
lateral inhibition GO:0046331 206 0.016
circulatory system development GO:0072359 82 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.015
organic substance catabolic process GO:1901575 308 0.015
phototaxis GO:0042331 21 0.015
regulation of protein localization GO:0032880 76 0.015
telencephalon development GO:0021537 2 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
single organism nuclear import GO:1902593 51 0.015
regulation of defense response GO:0031347 102 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
small molecule metabolic process GO:0044281 305 0.015
regulation of reproductive process GO:2000241 54 0.015
pigment biosynthetic process GO:0046148 36 0.014
regulation of cellular localization GO:0060341 136 0.014
regulation of membrane potential GO:0042391 35 0.014
regulation of establishment of protein localization GO:0070201 61 0.014
cellular catabolic process GO:0044248 372 0.014
exocrine system development GO:0035272 162 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
response to oxygen containing compound GO:1901700 200 0.014
cytosolic calcium ion transport GO:0060401 2 0.014
catabolic process GO:0009056 409 0.014
oocyte differentiation GO:0009994 145 0.014
developmental programmed cell death GO:0010623 138 0.014
actin cytoskeleton organization GO:0030036 206 0.013
protein targeting to nucleus GO:0044744 51 0.013
salivary gland development GO:0007431 162 0.013
pigmentation GO:0043473 75 0.013
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.013
positive regulation of cell size GO:0045793 21 0.013
cardiovascular system development GO:0072358 82 0.013
convergent extension GO:0060026 2 0.013
medium term memory GO:0072375 8 0.013
oocyte maturation GO:0001556 3 0.013
stress activated protein kinase signaling cascade GO:0031098 55 0.013
positive regulation of gtpase activity GO:0043547 43 0.013
rhythmic behavior GO:0007622 76 0.013
tissue death GO:0016271 102 0.013
developmental growth GO:0048589 280 0.013
response to inorganic substance GO:0010035 44 0.013
organ growth GO:0035265 56 0.013
regulation of hydrolase activity GO:0051336 97 0.013
circadian behavior GO:0048512 76 0.012
positive regulation of protein transport GO:0051222 37 0.012
response to organonitrogen compound GO:0010243 75 0.012
hematopoietic or lymphoid organ development GO:0048534 57 0.012
anatomical structure homeostasis GO:0060249 97 0.012
cellular lipid metabolic process GO:0044255 83 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.012
molting cycle GO:0042303 56 0.012
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.012
positive regulation of response to biotic stimulus GO:0002833 31 0.012
positive regulation of immune response GO:0050778 63 0.012
intracellular receptor signaling pathway GO:0030522 19 0.012
insulin receptor signaling pathway GO:0008286 25 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
single organism catabolic process GO:0044712 228 0.012
cellular protein complex assembly GO:0043623 71 0.012
chaeta morphogenesis GO:0008407 42 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.012
negative regulation of neuron death GO:1901215 18 0.012
establishment of planar polarity GO:0001736 87 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.012
r7 cell fate commitment GO:0007465 12 0.012
compound eye photoreceptor fate commitment GO:0001752 36 0.012
developmental growth involved in morphogenesis GO:0060560 65 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
monocarboxylic acid transport GO:0015718 3 0.011
imaginal disc fusion GO:0046528 19 0.011
skeletal muscle tissue development GO:0007519 13 0.011
ovarian follicle cell migration GO:0007297 121 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.011
regulation of hemocyte proliferation GO:0035206 37 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
positive regulation of immune system process GO:0002684 68 0.011
regulation of catabolic process GO:0009894 170 0.011
protein targeting GO:0006605 64 0.011
regulation of tube architecture open tracheal system GO:0035152 68 0.011
nephrocyte diaphragm assembly GO:0036059 3 0.011
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
long term memory GO:0007616 62 0.011
developmental pigmentation GO:0048066 68 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
negative regulation of neuron apoptotic process GO:0043524 14 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
regulation of molecular function GO:0065009 217 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
protein import GO:0017038 55 0.011
peptide biosynthetic process GO:0043043 42 0.011
response to endogenous stimulus GO:0009719 119 0.011
microtubule based transport GO:0010970 42 0.010
cell division GO:0051301 248 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
positive regulation of ras gtpase activity GO:0032320 36 0.010
positive regulation of signal transduction GO:0009967 223 0.010
immune effector process GO:0002252 98 0.010
cell cycle checkpoint GO:0000075 95 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
contractile actin filament bundle assembly GO:0030038 1 0.010
regulation of transport GO:0051049 181 0.010
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.010

inaE disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
disease of anatomical entity DOID:7 0 0.019
central nervous system disease DOID:331 0 0.014
nervous system disease DOID:863 0 0.014
neurodegenerative disease DOID:1289 0 0.011